Organic and Biological Chemistry

Research Output

Article

Structural analysis and identification of novel isoforms of the circadian clock gene period in the silk moth Bombyx mori

Takeda, Y., Chuman, Y., Shirasu, N., Sato, S., Matsushima, A., Kaneki, A., Tominaga, Y., Shimohigashi, Y. & Shimohigashi, M., Sep 1 2004, In : Zoological science. 21, 9, p. 903-915 13 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Structural Basis of Mitochondrial Scaffolds by Prohibitin Complexes: Insight into a Role of the Coiled-Coil Region

Yoshinaka, T., Kosako, H., Yoshizumi, T., Furukawa, R., Hirano, Y., Kuge, O., Tamada, T. & Koshiba, T., Sep 27 2019, In : iScience. 19, p. 1065-1078 14 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Structural evidence for endocrine disruptor bisphenol A binding to human nuclear receptor ERRγ

Matsushima, A., Kakuta, Y., Teramoto, T., Koshiba, T., Liu, X., Okada, H., Tokunaga, T., Kawabata, S. I., Kimura, M. & Shimohigashi, Y., Oct 1 2007, In : Journal of biochemistry. 142, 4, p. 517-524 8 p.

Research output: Contribution to journalArticle

147 Citations (Scopus)

Structural isoforms of the circadian neuropeptide PDF expressed in the optic lobes of the cricket Gryllus bimaculatus: Immunocytochemical evidence from specific monoclonal antibodies

Honda, T., Matsushima, A., Sumida, K., Chuman, Y., Sakaguchi, K., Onoue, H., Meinertzhagen, I. A., Shimohigashi, Y. & Shimohigashi, M., Nov 20 2006, In : Journal of Comparative Neurology. 499, 3, p. 404-421 18 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Subcellular localization of human neutral ceramidase expressed in HEK293 cells

Hwang, Y. H., Tani, M., Nakagawa, T., Okino, N. & Ito, M., May 27 2005, In : Biochemical and Biophysical Research Communications. 331, 1, p. 37-42 6 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Substrate recognition by mitochondrial processing peptidase toward the malate dehydrogenase precursor

Shimokata, K., Nishio, T., Song, M. C., Kitada, S., Ogishima, T. & Ito, A., Jan 1 1997, In : Journal of biochemistry. 122, 5, p. 1019-1023 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Suppression of fetal testicular cytochrome P450 17 by maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: A mechanism involving an initial effect on gonadotropin synthesis in the pituitary

Taketoh, J., Mutoh, J., Takeda, T., Ogishima, T., Takeda, S., Ishii, Y., Ishida, T. & Yamada, H., Mar 13 2007, In : Life Sciences. 80, 14, p. 1259-1267 9 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Synergistic effect of basic residues at positions 14-15 of nociceptin on binding affinity and receptor activation

Okada, K., Isozaki, K., Li, J., Matsushima, A., Nose, T., Costa, T. & Shimohigashi, Y., Oct 15 2008, In : Bioorganic and Medicinal Chemistry. 16, 20, p. 9261-9267 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Syntheses and Biological Activities of the LMNO, ent-LMNO, and NOPQR(S) Ring Systems of Maitotoxin

Onoue, H., Marubayashi, R., Ishikawa, E., Konoki, K., Torikai, K., Ebine, M., Murata, M. & Oishi, T., Jan 1 2017, In : Journal of Organic Chemistry. 82, 18, p. 9595-9618 24 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Synthesis and biological activity of the C'D'E'F' ring system of maitotoxin

Kunitake, M., Oshima, T., Konoki, K., Ebine, M., Torikai, K., Murata, M. & Oishi, T., Jun 6 2014, In : Journal of Organic Chemistry. 79, 11, p. 4948-4962 15 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Synthesis and biological activity of the QRS ring system of maitotoxin

Onoue, H., Baba, T., Konoki, K., Torikai, K., Ebine, M. & Oishi, T., Jan 1 2014, In : Chemistry Letters. 43, 12, p. 1904-1906 3 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Synthesis and complete structure determination of a sperm-activating and -attracting factor isolated from the ascidian ascidia sydneiensis

Watanabe, T., Shibata, H., Ebine, M., Tsuchikawa, H., Matsumori, N., Murata, M., Yoshida, M., Morisawa, M., Lin, S., Yamauchi, K., Sakai, K. & Oishi, T., Apr 27 2018, In : Journal of Natural Products. 81, 4, p. 985-997 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Synthesis and properties of fullerene (C70) complexes of 2,6-bis(porphyrin)-substituted pyrazine derivatives bound to a Pd(II) ion

Eda, Y., Itoh, K., Ito, Y. N., Fujitsuka, M., Majima, T. & Kawato, T., Sep 1 2010, In : Supramolecular Chemistry. 22, 9, p. 517-523 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Synthesis and Stereochemical Revision of the C31–C67 Fragment of Amphidinol 3

Wakamiya, Y., Ebine, M., Murayama, M., Omizu, H., Matsumori, N., Murata, M. & Oishi, T., May 22 2018, In : Angewandte Chemie - International Edition. 57, 21, p. 6060-6064 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Synthesis and structure revision of the C43-C67 part of amphidinol 3

Ebine, M., Kanemoto, M., Manabe, Y., Konno, Y., Sakai, K., Matsumori, N., Murata, M. & Oishi, T., Jun 26 2013, In : Organic Letters. 15, 11, p. 2846-2849 4 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Synthesis of 6/6/6-tricyclic ether system via Achmatowicz and intramolecular oxa-michael reactions

Yamamoto, H., Torikai, K., Ebine, M. & Oishi, T., Jan 1 2018, In : Heterocycles. 97, 1, p. 158-162 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Synthesis of 6-F-ergosterol and its influence on membrane-permeabilization of amphotericin B and amphidinol 3

Kasai, Y., Matsumori, N., Ueno, H., Nonomura, K., Yano, S., Michio, M. & Oishi, T., Mar 1 2011, In : Organic and Biomolecular Chemistry. 9, 5, p. 1437-1442 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Synthesis of a complete set of L-difluorophenylalanines, L-(F2)Phe, as molecular explorers for the CH/π interaction between peptide ligand and receptor

Fujita, T., Nose, T., Matsushima, A., Okada, K., Asai, D., Yamauchi, Y., Shirasu, N., Honda, T., Shigehiro, D. & Shimohigashi, Y., Feb 5 2000, In : Tetrahedron Letters. 41, 6, p. 923-927 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Synthesis of an analog of amphidinol 3 corresponding to the c31-c67 section

Koge, T., Wakamiya, Y., Ebine, M. & Oishi, T., Jan 1 2018, In : Heterocycles. 96, 7, p. 1197-1202 6 p.

Research output: Contribution to journalArticle

Synthesis of anti-tubercular marine alkaloids denigrins A and B

Karak, M., Oishi, T. & Torikai, K., Jul 18 2018, In : Tetrahedron Letters. 59, 29, p. 2800-2803 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Synthesis of a truncated analog of amphidinol 3 corresponding to the C21C39/C52C67 section

Ebine, M., Takada, Y., Yanai, N. & Oishi, T., Jan 1 2017, In : Chemistry Letters. 46, 5, p. 662-664 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Synthesis of mannosylinositol phosphorylceramides is involved in maintenance of cell integrity of yeast Saccharomyces cerevisiae

Morimoto, Y. & Tani, M., Feb 1 2015, In : Molecular Microbiology. 95, 4, p. 706-722 17 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Synthesis of pyrazine acetals by the biased reaction of symmetric 2,5-bis(chloromethyl) or 2,3,5,6-tetrakis(chloromethyl) substituents on pyrazine ring with sodium alkoxides

Eda, Y., Odazaki, Y., Mizutani, A., Ito, Y. N. & Kawato, T., Apr 14 2008, In : Tetrahedron Letters. 49, 16, p. 2519-2522 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Synthesis of the CDE/FG ring models of prymnesins: Reassignment of the relative configuration of the E/F ring juncture

Sasaki, M., Ebine, M., Takagi, H., Takakura, H., Shida, T., Satake, M., Oshima, Y., Igarashi, T. & Yasumoto, T., Apr 29 2004, In : Organic Letters. 6, 9, p. 1501-1504 4 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Synthetic study of ciguatoxin. Absolute configuration of the C2 hydroxy group

Oguri, H., Hishiyama, S., Sato, O., Oishi, T., Hirama, M., Murata, M., Yasumoto, T. & Harada, N., Mar 3 1997, In : Tetrahedron. 53, 9, p. 3057-3072 16 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Tam41 is a CDP-diacylglycerol synthase required for cardiolipin biosynthesis in mitochondria

Tamura, Y., Harada, Y., Nishikawa, S. I., Yamano, K., Kamiya, M., Shiota, T., Kuroda, T., Kuge, O., Sesaki, H., Imai, K., Tomii, K. & Endo, T., May 7 2013, In : Cell metabolism. 17, 5, p. 709-718 10 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Ten-membered neocarzinostatin chromophore analogs leading to σ,σ-biradical via a cumulene intermediate

Kawata, S., Oishi, T. & Hirama, M., Jun 27 1994, In : Tetrahedron Letters. 35, 26, p. 4595-4598 4 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

The AAA+ ATPase ATAD3A controls mitochondrial dynamics at the interface of the inner and outer membranes

Gilquin, B., Taillebourg, E., Cherradi, N., Hubstenberger, A., Gay, O., Merle, N., Assard, N., Fauvarque, M. O., Tomohiro, S., Kuge, O. & Baudier, J., Apr 2010, In : Molecular and cellular biology. 30, 8, p. 1984-1996 13 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

The first asymmetric epoxidation using a combination of achiral (salen)manganese(III) complex and chiral amine

Hashihayata, T., Ito, Y. & Katsuki, T., Jul 14 1997, In : Tetrahedron. 53, 28, p. 9541-9552 12 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

The mucin box and signal/anchor sequence of rat neutral ceramidase recruit bacterial sphingomyelinase to the plasma membrane

Nakagawa, T., Tani, M., Sueyoshi, N. & Ito, M., Jun 6 2011, In : Bioscience, Biotechnology and Biochemistry. 75, 5, p. 987-990 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

The Structure of the Bimolecular Complex between Amphotericin B and Ergosterol in Membranes Is Stabilized by Face-to-Face van der Waals Interaction with Their Rigid Cyclic Cores

Nakagawa, Y., Umegawa, Y., Matsushita, N., Yamamoto, T., Tsuchikawa, H., Hanashima, S., Oishi, T., Matsumori, N. & Murata, M., Jun 21 2016, In : Biochemistry. 55, 24, p. 3392-3402 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The VDAC2-BAK axis regulates peroxisomal membrane permeability

Hosoi, K., Miyata, N., Mukai, S., Furuki, S., Okumoto, K., Cheng, E. H. & Fujiki, Y., Mar 6 2017, In : Journal of Cell Biology. 216, 3, p. 709-722

Research output: Contribution to journalArticle

22 Citations (Scopus)

TMEM14C is required for erythroid mitochondrial heme metabolism

Yien, Y. Y., Robledo, R. F., Schultz, I. J., Takahashi-Makise, N., Gwynn, B., Bauer, D. E., Dass, A., Yi, G., Li, L., Hildick-Smith, G. J., Cooney, J. D., Pierce, E. L., Mohler, K., Dailey, T. A., Miyata, N., Kingsley, P. D., Garone, C., Hattangadi, S. M., Huang, H., Chen, W. & 15 others, Keenan, E. M., Shah, D. I., Schlaeger, T. M., Dimauro, S., Orkin, S. H., Cantor, A. B., Palis, J., Koehler, C. M., Lodish, H. F., Kaplan, J., Ward, D. M., Dailey, H. A., Phillips, J. D., Peters, L. L. & Paw, B. H., Oct 1 2014, In : Journal of Clinical Investigation. 124, 10, p. 4294-4304 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Total synthesis, structure revision, and absolute configuration of (-)-brevenal

Fuwa, H., Ebine, M., Bourdelais, A. J., Baden, D. G. & Sasaki, M., Dec 27 2006, In : Journal of the American Chemical Society. 128, 51, p. 16989-16999 11 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)

Total synthesis of (-)-brevenal: A streamlined strategy for practical synthesis of polycyclic ethers

Ebine, M., Fuwa, H. & Sasaki, M., Dec 2 2011, In : Chemistry - A European Journal. 17, 49, p. 13754-13761 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Total synthesis of (-)-brevenal: A concise synthetic entry to the pentacyclic polyether core

Ebine, M., Fuwa, H. & Sasaki, M., Jun 5 2008, In : Organic Letters. 10, 11, p. 2275-2278 4 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Total Synthesis of Amphidinol 3: A General Strategy for Synthesizing Amphidinol Analogues and Structure-Activity Relationship Study

Wakamiya, Y., Ebine, M., Matsumori, N. & Oishi, T., Feb 19 2020, In : Journal of the American Chemical Society. 142, 7, p. 3472-3478 7 p.

Research output: Contribution to journalArticle

Total synthesis of the proposed structure of brevenal

Fuwa, H., Ebine, M. & Sasaki, M., Aug 2 2006, In : Journal of the American Chemical Society. 128, 30, p. 9648-9650 3 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Triazoyl-phenyl linker system enhancing the aqueous solubility of a molecular probe and its efficiency in affinity labeling of a target protein for jasmonate glucoside

Tamura, S., Inomata, S., Ebine, M., Genji, T., Iwakura, I., Mukai, M., Shoji, M., Sugai, T. & Ueda, M., Jan 1 2013, In : Bioorganic and Medicinal Chemistry Letters. 23, 1, p. 188-193 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Tritium-labelled isovaleryl-RYYRIK-NH2 as potential antagonist probe for ORL1 nociceptin receptor

Inamine, S., Nishimura, H., Li, J., Isozaki, K., Matsushima, A., Costa, T. & Shimohigashi, Y., Nov 1 2014, In : Bioorganic and Medicinal Chemistry. 22, 21, p. 5902-5909 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Tuned Classical Thermal Aromatization Furnishing an Estrogenic Benzoacridine

Koga, R., Oishi, T. & Torikai, K., Dec 17 2015, In : Synlett. 26, 20, p. 2801-2805 5 p., st-2015-s0585-c.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Unified synthesis of the DEF and GhI ring systems of maitotoxin

Yasudomi, T., Yakushiji, H., Torikai, K., Ebine, M. & Oishi, T., Jan 1 2019, In : Chemistry Letters. 48, 9, p. 1156-1159 4 p.

Research output: Contribution to journalArticle

VID22 is required for transcriptional activation of the PSD2 gene in the yeast Saccharomyces cerevisiae

Miyata, N., Miyoshi, T., Yamaguchi, T., Nakazono, T., Tani, M. & Kuge, O., Dec 15 2015, In : Biochemical Journal. 472, 3, p. 319-328 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Voltammetric study of the boric acid-salicylaldehyde-H-acid ternary system and its application to the voltammetric determination of boron

Kajiwara, M., Ito, Y. N., Miyazaki, Y., Fujimori, T., Takehara, K. & Yoshimura, K., Feb 14 2015, In : Physical Chemistry Chemical Physics. 17, 6, p. 4578-4588 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
62 Citations (Scopus)

Yeast lacking the amphiphysin family protein Rvs167 is sensitive to disruptions in sphingolipid levels

Toume, M. & Tani, M., Aug 1 2016, In : FEBS Journal. p. 2911-2928 18 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

α-Helix-peptides comprising the human nuclear receptor ERRγ competitively provoke inhibition of functional homomeric dimerization

Liu, X., Nishimura, H., Fujiyama, A., Matsushima, A., Shimohigashi, M. & Shimohigashi, Y., Nov 4 2016, In : Biopolymers. p. 547-554 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

ζ-COP, a subunit of coatomer, is required for COP-coated vesicle assembly

Kuge, O., Hara-Kuge, S., Orci, L., Ravazzola, M., Amherdt, M., Tanigawa, G., Wieland, F. T. & Rothman, J. E., Dec 1 1993, In : Journal of Cell Biology. 123, 6 II, p. 1727-1734 8 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

核内受容体が示す有害化学物質ビスフェノール応答

Translated title of the contribution: Structure-function studies between the hormone-disrupting chemical bisphenols and the nuclear receptorsMatsushima, A., Dec 2016, In : Seikagaku. The Journal of Japanese Biochemical Society. 88, 6, p. 733-43 11 p.

Research output: Contribution to journalArticle