Pediatric Dentistry & Special Needs Dentistry

Research Output 1996 2019

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Article
2019
1 Citation (Scopus)
Dental Pulp
Oxidative stress
Deciduous Tooth
Stem cells
Folic Acid

Induction of bone repair in rat calvarial defects using a combination of hydroxyapatite with phosphatidylserine liposomes

Hatakeyama, J., Anan, H., Hatakeyama, Y., Matsumoto, N., Takayama, F., Wu, Z., Matsuzaki, E., Minakami, M., Izumi, T. & Nakanishi, H., Jan 1 2019, In : Journal of Oral Science. 61, 1, p. 111-118 8 p.

Research output: Contribution to journalArticle

Open Access
Phosphatidylserines
Durapatite
Liposomes
Bone and Bones
Bone Regeneration
1 Citation (Scopus)
Open Access
Dental Pulp
Stem cells
Pulp
Stem Cells
Mutation
Leigh Disease
Bezafibrate
Deciduous Tooth
Organelle Biogenesis
Stem cells
2 Citations (Scopus)
Dental Pulp
Dopaminergic Neurons
Brain-Derived Neurotrophic Factor
Neurites
Attention Deficit Disorder with Hyperactivity
Dental Pulp
Oxidative stress
Deciduous Tooth
Neural Crest
Cleft Palate
2018
1 Citation (Scopus)
Dentinogenesis
Mitochondrial Dynamics
Dynamins
Dental Papilla
Odontoblasts
2 Citations (Scopus)

Altered development of dopaminergic neurons differentiated from stem cells from human exfoliated deciduous teeth of a patient with Down syndrome

Pham, T. T. M., Kato, H., Yamaza, H., Masuda, K., Hirofuji, Y., Sato, H., Nguyen, H. T. N., Han, X., Zhang, Y., Taguchi, T. & Nonaka, K., Aug 31 2018, In : BMC neurology. 18, 1, 132.

Research output: Contribution to journalArticle

Deciduous Tooth
Dopaminergic Neurons
Down Syndrome
Stem Cells
Dopamine
1 Citation (Scopus)
Deciduous Tooth
Dopaminergic Neurons
Neurites
Stem cells
Neurons
4 Citations (Scopus)
Methyl-CpG-Binding Protein 2
Rett Syndrome
Deciduous Tooth
Dopaminergic Neurons
Stem cells
2017
26 Citations (Scopus)

Cathepsin B plays a critical role in inducing Alzheimer's disease-like phenotypes following chronic systemic exposure to lipopolysaccharide from Porphyromonas gingivalis in mice

Wu, Z., Ni, J., Liu, Y., Teeling, J. L., Takayama, F., Collcutt, A., Ibbett, P. & Nakanishi, H., Oct 2017, In : Brain, Behavior, and Immunity. 65, p. 350-361 12 p.

Research output: Contribution to journalArticle

Cathepsin B
Porphyromonas gingivalis
Microglia
Lipopolysaccharides
Alzheimer Disease
8 Citations (Scopus)

Direct effects of mitochondrial dysfunction on poor bone health in Leigh syndrome

Kato, H., Han, X., Yamaza, H., Masuda, K., Hirofuji, Y., Sato, H., Pham, T. T. M., Taguchi, T. & Nonaka, K., Nov 4 2017, In : Biochemical and Biophysical Research Communications. 493, 1, p. 207-212 6 p.

Research output: Contribution to journalArticle

Leigh Disease
Mitochondrial Diseases
Bone
Health
Bone and Bones
5 Citations (Scopus)

Dysfunction in diurnal synaptic responses and social behavior abnormalities in cathepsin S-deficient mice

Takayama, F., Zhang, X., Hayashi, Y., Take, H. & Nakanishi, H., Aug 19 2017, In : Biochemical and Biophysical Research Communications. 490, 2, p. 447-452 6 p.

Research output: Contribution to journalArticle

cathepsin S
Social Behavior
Neurons
Clocks
Cats

Engineering of Systematic Elimination of a Targeted Chromosome in Human Cells

Sato, H., Kato, H., Yamaza, H., Masuda, K., Nguyen, H. T. N., Pham, T. T. M., Han, X., Hirofuji, Y. & Nonaka, K., Jan 1 2017, In : BioMed Research International. 2017, 6037159.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 21
Human Chromosomes
Chromosomes
Cells
Trisomy
8 Citations (Scopus)

Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice

Liu, Y., Take, H., Nakanishi, Y., Ni, J., Hayashi, Y., Takayama, F., Zhou, Y., Kadawaki, T. & Nakanishi, H., Dec 1 2017, In : Scientific reports. 7, 1, 11759.

Research output: Contribution to journalArticle

PAR-2 Receptor
Porphyromonas gingivalis
Extracellular Signal-Regulated MAP Kinases
Microglia
Cell Movement
8 Citations (Scopus)

Mitochondria regulate the differentiation of stem cells from human exfoliated deciduous teeth

Kato, H., Pham, T. T. M., Yamaza, H., Masuda, K., Hirofuji, Y., Han, X., Sato, H., Taguchi, T. & Nonaka, K., Jan 1 2017, In : Cell structure and function. 42, 2, p. 105-116 12 p.

Research output: Contribution to journalArticle

Carbonyl Cyanide m-Chlorophenyl Hydrazone
Rotenone
Deciduous Tooth
Mitochondria
Stem Cells
1 Citation (Scopus)

Overexpression of Cathepsin E Interferes with Neuronal Differentiation of P19 Embryonal Teratocarcinoma Cells by Degradation of N-cadherin

Harada, Y., Takayama, F., Tanabe, K., Ni, J., Hayashi, Y., Yamamoto, K., Wu, Z. & Nakanishi, H., Apr 1 2017, In : Cellular and molecular neurobiology. 37, 3, p. 437-443 7 p.

Research output: Contribution to journalArticle

Cathepsin E
Teratocarcinoma
Cadherins
Neurons
Cell Differentiation
2016
9 Citations (Scopus)

Dihydroorotate dehydrogenase depletion hampers mitochondrial function and osteogenic differentiation in osteoblasts

Fang, J., Yamaza, H., Uchiumi, T., Hoshino, Y., Masuda, K., Hirofuji, Y., Wagener, F. A. D. T. G., Kang, D. & Nonaka, K., Jun 1 2016, In : European Journal of Oral Sciences. 124, 3, p. 241-245 5 p.

Research output: Contribution to journalArticle

Osteoblasts
Small Interfering RNA
Adenosine Triphosphate
Cell Proliferation
dihydroorotate dehydrogenase
12 Citations (Scopus)

Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y 6 receptor system

Takayama, F., Hayashi, Y., Wu, Z., Liu, Y. & Nakanishi, H., Jul 21 2016, In : Scientific reports. 6, 30006.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Uridine Diphosphate
Microglia
Bacteria
Adenosine Triphosphate
2015
4 Citations (Scopus)
Mixed Dentition
Odontogenic Tumors
Bicuspid
Tooth Germ
Tooth
2014
1 Citation (Scopus)

Clinical approach to a suspected case of first branchial arch syndrome

Yamaguchi, N., Nakamura, S., Yamaza, H., Nishigaki, S., Masuda, K., Yanagita, K. I. & Nonaka, K., 2014, In : Case Reports in Medicine. 2014, 506804.

Research output: Contribution to journalArticle

Branchial Region
Cephalometry
Ear
Hearing Loss
Goldenhar Syndrome
2013
17 Citations (Scopus)

Brazilian green propolis suppresses the hypoxia-induced neuroinflammatory responses by inhibiting NF- B activation in microglia

Wu, Z., Zhu, A., Takayama, F., Okada, R., Liu, Y., Harada, Y., Wu, S. & Nakanishi, H., Sep 3 2013, In : Oxidative medicine and cellular longevity. 906726.

Research output: Contribution to journalArticle

Propolis
Microglia
Chemical activation
Interleukin-1
Interleukin-6
2 Citations (Scopus)

Possible involvement of aiPLA2 in the phosphatidylserine-containing liposomes induced production of PGE2 and PGD2 in microglia

Takayama, F., Wu, Z., Ma, H. M., Okada, R., Hayashi, Y. & Nakanishi, H., Jul 12 2013, In : Journal of Neuroimmunology. 262, 1-2, p. 121-124 4 p.

Research output: Contribution to journalArticle

Prostaglandin D2
Phosphatidylserines
Microglia
Dinoprostone
Liposomes
2010

Defining the immunological phenotype of Fc receptor-like B (FCRLB) deficient mice: Confounding role of the inhibitory FcγRIIb

Masuda, K., Mori, H., Ohara, O., Nakayama, M., Wang, J. Y. & Burrows, P. D., Sep 24 2010, In : Cellular Immunology. 266, 1, p. 24-31 8 p.

Research output: Contribution to journalArticle

Fc Receptors
B-Lymphocytes
Phenotype
Antibody Formation
Alleles
2009

A critical role for REV1 in regulating the induction of C:G transitions and A:T mutations during Ig gene hypermutation

Masuda, K., Ouchida, R., Li, Y., Gao, X., Mori, H. & Wang, J. Y., Aug 1 2009, In : Journal of Immunology. 183, 3, p. 1846-1850 5 p.

Research output: Contribution to journalArticle

Open Access
Immunoglobulin Genes
Mutation
Transferases
B-Lymphocytes
Deoxycytidine
546 Citations (Scopus)

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

Ishihara, N., Nomura, M., Jofuku, A., Kato, H., Suzuki, S. O., Masuda, K., Otera, H., Nakanishi, Y., Nonaka, I., Goto, Y. I., Taguchi, N., Morinaga, H., Maeda, M., Takayanagi, R., Yokota, S. & Mihara, K., Jul 6 2009, In : Nature Cell Biology. 11, 8, p. 958-966 9 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Synapses
Embryonic Development
Prosencephalon
Apoptosis
2008
44 Citations (Scopus)

A Lysosomal Protein Negatively Regulates Surface T Cell Antigen Receptor Expression by Promoting CD3ζ-Chain Degradation

Ouchida, R., Yamasaki, S., Hikida, M., Masuda, K., Kawamura, K., Wada, A., Mochizuki, S., Tagawa, M., Sakamoto, A., Hatano, M., Tokuhisa, T., Koseki, H., Saito, T., Kurosaki, T. & Wang, J. Y., Jul 18 2008, In : Immunity. 29, 1, p. 33-43 11 p.

Research output: Contribution to journalArticle

Surface Antigens
T-Cell Antigen Receptor
T-Lymphocytes
Thymocytes
Ubiquitin

DNA polymerase η is a limiting factor for A:T mutations in Ig genes and contributes to antibody affinity maturation

Masuda, K., Ouchida, R., Yokoi, M., Hanaoka, F., Azuma, T. & Wang, J. Y., Dec 1 2008, In : European Journal of Immunology. 38, 10, p. 2796-2805 10 p.

Research output: Contribution to journalArticle

Immunoglobulin Genes
Antibody Affinity
DNA-Directed DNA Polymerase
Mutation
Germinal Center
2007

DNA polymerases η and θ function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes

Masuda, K., Ouchida, R., Hikida, M., Kurosaki, T., Yokoi, M., Masutani, C., Seki, M., Wood, R. D., Hanaoka, F. & O-Wang, J., Jun 15 2007, In : Journal of Biological Chemistry. 282, 24, p. 17387-17394 8 p.

Research output: Contribution to journalArticle

Open Access
Immunoglobulin Genes
DNA-Directed DNA Polymerase
Genes
Mutation
Nucleotides
2006

Absence of DNA polymerase θ results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes

Masuda, K., Ouchida, R., Hikida, M., Nakayama, M., Ohara, O., Kurosaki, T. & O-Wang, J., Nov 8 2006, In : DNA Repair. 5, 11, p. 1384-1391 8 p.

Research output: Contribution to journalArticle

Immunoglobulin Genes
Mutation Rate
DNA-Directed DNA Polymerase
Immunoglobulins
Genes

Role of DNA polymerase θ in tolerance of endogenous and exogenous DNA damage in mouse B cells

Ukai, A., Maruyama, T., Mochizuki, S., Ouchida, R., Masuda, K., Kawamura, K., Tagawa, M., Kinoshita, K., Sakamoto, A., Tokuhisa, T. & O-Wang, J., Feb 1 2006, In : Genes to Cells. 11, 2, p. 111-121 11 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
DNA Damage
B-Lymphocytes
Methyl Methanesulfonate
DNA Repair
2005
87 Citations (Scopus)

DNA polymerase θ contributes to the generation of C/G mutations during somatic hypermutation of Ig genes

Masuda, K., Ouchida, R., Takeuchi, A., Saito, T., Koseki, H., Kawamura, K., Tagawa, M., Tokuhisa, T., Azuma, T. & O-Wang, J., Sep 27 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 39, p. 13986-13991 6 p.

Research output: Contribution to journalArticle

Open Access
Immunoglobulin Genes
DNA-Directed DNA Polymerase
Mutation
Uracil-DNA Glycosidase
Immunoglobulin Variable Region

FcRY, an Fc receptor related gene differentially expressed during B lymphocyte development and activation

Masuda, K., Davis, R. S., Maruyama, T., Zhang, J., He, T., Cooper, M. D., O-Wang, J. & Burrows, P. D., Dec 19 2005, In : Gene. 363, 1-2, p. 32-40 9 p.

Research output: Contribution to journalArticle

Fc Receptors
Lymphocyte Activation
B-Lymphocytes
Genes
Cell Cycle
2004
81 Citations (Scopus)

In situ expression of RANKL, RANK, osteoprotegerin and cytokines in osteoclasts of rat periodontal tissue

Ogasawara, T., Yoshimine, Y., Kiyoshima, T., Kobayashi, I., Matsuo, K., Akamine, A. & Sakai, H., Feb 1 2004, In : Journal of Periodontal Research. 39, 1, p. 42-49 8 p.

Research output: Contribution to journalArticle

Osteoprotegerin
Osteoclasts
Cytokines
Interleukin-1
Periodontal Ligament
2003
7 Citations (Scopus)
Glass Ionomer Cements
Zinc Oxide
Eugenol
Bone and Bones
Histocompatibility
7 Citations (Scopus)

In vitro evaluation of the cytocompatibility of a glass-ionomer cement sealer

Yoshimine, Y., Yamamoto, M., Ogasawara, T., Koishi, Y., Tanabe, K., Hashiguchi, I. & Akamine, A., Jul 2003, In : Journal of Endodontics. 29, 7, p. 453-455 3 p.

Research output: Contribution to journalArticle

Glass Ionomer Cements
Periodontal Ligament
Dental Pulp Cavity
Zinc Oxide
Eugenol
1998
42 Citations (Scopus)

Affinity maturation in Lyn kinase-deficient mice with defective germinal center formation

Kato, J., Motoyama, N., Taniuchi, I., Takeshita, H., Toyoda, M., Masuda, K. & Watanabe, T., May 15 1998, In : Journal of Immunology. 160, 10, p. 4788-4795 8 p.

Research output: Contribution to journalArticle

Germinal Center
Phosphotransferases
Immunoglobulin Class Switching
B-Lymphocytes
CD40 Ligand
1997
11 Citations (Scopus)

Reduced susceptibility to Fas-mediated apoptosis in B-1 cells

Masuda, K., Wang, J. & Watanabe, T., Mar 3 1997, In : European Journal of Immunology. 27, 2, p. 449-455 7 p.

Research output: Contribution to journalArticle

Apoptosis
CD40 Ligand
Inbred NZB Mouse
B-Lymphocytes
Peripheral Tolerance
1996
22 Citations (Scopus)

Regulation of bcl-x(L) expression and Fas susceptibility in mouse B cells by CD40 ligation, surface IgM crosslinking and IL-4

Koizumi, T., Wang, J., Suzuki, Y., Masuda, K. & Watanabe, T., Nov 1 1996, In : Molecular Immunology. 33, 16, p. 1247-1253 7 p.

Research output: Contribution to journalArticle

Interleukin-4
Ligation
Immunoglobulin M
B-Lymphocytes
Apoptosis