Research Output

1997
18 Citations (Scopus)

Production of antibody against cytosolic 54kDa protein in rat liver evidence of the significant induction by a highly toxic coplanar polychlorinated biphenyl

Ishida, T., Ishii, Y., Tasaki, K., Ariyoshi, N. & Oguri, K., Jan 1 1997, In : Fukuoka Acta Medica. 88, 5, p. 3-11 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Quaternary structure-dependent idiotope and antigen binding of a monoclonal antibody specific for conformational epitope on type II collagen

Ito, H. O., Ueda, T., Hashimoto, Y., Imoto, T. & Koga, T., Sep 22 1997, In : Cellular and Molecular Life Sciences. 53, 1, p. 51-60 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Significant suppression of aldolase B, carbonic anhydrase III and alcohol dehydrogenase in liver cytosol of rats treated with a highly toxic coplanar PCB

Kato, H., Ishii, Y., Hatsumura, M., Ishida, T., Nakayama, I., Ariyoshi, N. & Oguri, K., Jan 1 1997, In : Japanese Journal of Toxicology and Environmental Health. 43, 1, p. P20

Research output: Contribution to journalArticle

Significant suppression of rat liver aldolase B by a toxic coplanar polychlorinated biphenyl, 3,3',4,4',5-pentachlorobiphenyl

Ishii, Y., Kato, H., Hatsumura, M., Ishida, T., Ariyoshi, N. & Oguri, K., Jan 15 1997, In : Toxicology. 116, 1-3, p. 193-199 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Sinulobatins A ~ D, new amphilectane-type diterpenoids from the Japanese soft coral Sinularia nanolobata

Yamada, K., Ujiie, T., Yoshida, K., Miyamoto, T. & Higuchi, R., Mar 31 1997, In : Tetrahedron. 53, 13, p. 4569-4578 10 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Synthesis of a hematoside analog containing phytosphingosine and α-hydroxfatty acid

Sugata, T., Kan, Y., Nagaregawa, Y., Miyamoto, T. & Higuchi, R., Jan 1 1997, In : Journal of Carbohydrate Chemistry. 16, 6, p. 917-925 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
1996

A coplanar PCB induces a selenium binding protein as a major cytosolic protein in rat liver

Ishii, Y., Hatsumura, M., Ishida, T., Ariyoshi, N. & Oguri, K., Jan 1 1996, In : Chemosphere. 32, 3, p. 509-515 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

A mutation study of catalytic residue Asp 52 in hen egg lysozyme

Hashimoto, Y., Yamada, K., Motoshima, H., Omura, T., Yamada, H., Yasukochi, T., Miki, T., Ueda, T. & Imoto, T., Jan 1996, In : Journal of biochemistry. 119, 1, p. 145-150 6 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Analysis of the transition state in the unfolding of hen lysozyme by introduction of Gly-Pro and Pro-Gly sequences at the same site

Motoshima, H., Ueda, T. & Imoto, T., Jun 1996, In : Journal of biochemistry. 119, 6, p. 1019-1023 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Biologically active glycosides from asteroida, XXXIV: Isolation and structure of cerebrosides from the starfish Stellaster equestris

Higuchi, R., Harano, Y., Mitsuyuki, M., Isobe, R., Yamada, K., Miyamoto, T. & Komori, T., Apr 1996, In : Liebigs Annales. 4, p. 593-599 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Biologically active glycosides from asteroidea, 35: Isolation and structure of four new steroid glycoside di-O-sulfates from the starfish Asteropecten latespinosus

Higuchi, R., Fujita, M., Matsumoto, S., Yamada, K., Miyamoto, T. & Sasaki, T., May 1996, In : Liebigs Annales. 5, p. 837-840 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Cannabis 25, biotransformation of cannabidiol and cannabidiolic acid by Pinellia ternata tissue segments

Tanaka, H., Takahashi, R., Morimoto, S. & Shoyama, Y., Jan 1 1996, In : Plant Cell Reports. 15, 11, p. 819-823 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Cathepsin B in the Growth of Colorectal Cancer: Suppressive Effect of Leupeptin on the Growth of DMH-induced Rat Colon Neoplasm

Satoh, Y., Higashi, T., Nouso, K., Shiota, T., Kinugasa, N., Yoshida, K., Uematsu, S., Nakatsukasa, H., Nishimura, Y. & Tsuji, T., Dec 1 1996, In : Acta medica Okayama. 50, 6, p. 299-303 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Cathepsin B in the Growth of Colorectal Cancer: Increased Activity of Cathepsin B in Human Colorectal Cancer

Satoh, Y., Higashi, T., Nouso, K., Shiota, T., Kinugasa, N., Yoshida, K., Uematsu, S., Nakatsukasa, H., Nishimura, Y. & Tsuji, T., Dec 1 1996, In : Acta medica Okayama. 50, 6, p. 305-311 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
12 Citations (Scopus)

Dorisenones, cytotoxic spongian diterpenoids, from the nudibranch Chromodoris obsoleta

Miyamoto, T., Sakamoto, K., Arao, K., Komori, T., Higuchi, R. & Sasaki, T., Jun 10 1996, In : Tetrahedron. 52, 24, p. 8187-8198 12 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Effective renaturation of denatured and reduced immunoglobulin G in vitro without assistance of chaperone

Maeda, Y., Ueda, T. & Imoto, T., Jan 1996, In : Protein Engineering. 9, 1, p. 95-100 6 p.

Research output: Contribution to journalArticle

Open Access
28 Citations (Scopus)

Effect of additives on the renaturation of reduced lysozyme in the presence of 4 M urea

Maeda, Y., Yamada, H., Ueda, T. & Imoto, T., May 1996, In : Protein Engineering. 9, 5, p. 461-465 5 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)

Effect on DNA topology by DnaA protein, the initiation factor of chromosomal DNA replication in Escherichia coli

Mizushima, T., Katayama, T. & Sekimizu, K., Sep 22 1996, In : Biochemistry. 35, 35, p. 11512-11516 5 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
11 Citations (Scopus)

Immunoaffinity column chromatography against forskolin using an anti-forskolin monoclonal antibody and its application

Yanagihara, H., Sakata, R., Minami, H., Tanaka, H., Shoyama, Y. & Murakami, H., Dec 10 1996, In : Analytica Chimica Acta. 335, 1-2, p. 63-70 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Influence of cluster formation of acidic phospholipids on decrease in the affinity for ATP of DnaA protein

Mizushima, T., Ishikawa, Y., Obana, E., Hase, M., Kubota, T., Katayama, T., Kunitake, T., Watanabe, E. & Sekimizu, K., Feb 16 1996, In : Journal of Biological Chemistry. 271, 7, p. 3633-3638 6 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Molecular design of inhibitors of in vitro oriC DNA replication based on the potential to block the ATP binding of DnaA protein

Mizushima, T., Sasaki, S., Ohishi, H., Kobayashi, M., Katayama, T., Miki, T., Maeda, M. & Sekimizu, K., Oct 19 1996, In : Journal of Biological Chemistry. 271, 41, p. 25178-25183 6 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Monoclonal antibody based enzyme immunoassay for marihuana (cannabinoid) compounds

Tanaka, H., Goto, Y. & Shoyama, Y., Jan 1 1996, In : Journal of Immunoassay. 17, 4, p. 321-342 22 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)
81 Citations (Scopus)

Purification of a phenobarbital-inducible UDP-glucuronosyltransferase isoform from dog liver which catalyzes morphine and testosterone glucuronidation

Oguri, K., Kurogi, A., Yamabe, K. I., Tanaka, M., Yoshisue, K., Ishii, Y. & Yoshimura, H., Jan 15 1996, In : Archives of Biochemistry and Biophysics. 325, 2, p. 159-166 8 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Rat primary T cells expressing HTLV-I tax gene transduced by a retroviral vector: In vitro and in vivo characterization

Murata, K., Fujita, M., Honda, T., Yamada, Y., Tomonaga, M. & Shiku, H., 1996, In : International Journal of Cancer. 68, 1, p. 102-108 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Reduced immunogenicity of monomethoxypolyethylene glycol-modified lysozyme for activation of T cells

So, T., Ito, H. O., Koga, T., Ueda, T. & Imoto, T., Jan 1 1996, In : Immunology Letters. 49, 1-2, p. 91-97 7 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Roles of dopamine D1 receptors in Δ9-tetrahydrocannabinol-induced expression of Fos protein in the rat brain

Miyamoto, A., Yamamoto, T., Ohno, M., Watanabe, S., Tanaka, H., Morimoto, S. & Shoyama, Y., Feb 26 1996, In : Brain Research. 710, 1-2, p. 234-240 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
20 Citations (Scopus)

Situation of monomethoxypolyethylene glycol covalently attached to lysozyme

So, T., Ueda, T., Abe, Y., Nakamata, T. & Imoto, T., Jun 1996, In : Journal of biochemistry. 119, 6, p. 1086-1093 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Stabilization of lysozyme by introducing N-glycosylation signal sequence

Ueda, T., Iwashita, H., Hashimoto, Y. & Imoto, T., Jan 1 1996, In : Journal of Biochemistry. 119, 1, p. 157-161 5 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

The nucleoid protein H-NS facilitates chromosome DNA replication in Escherichia coli dnaA mutants

Katayama, T., Takata, M. & Sekimizu, K., Jan 1 1996, In : Journal of bacteriology. 178, 19, p. 5790-5792 3 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

The possible role of nitric oxide in relaxations and excitatory neuroeffector transmission in the cat airway

Tanaka, H., Jing, L., Takahashi, S. & Ito, Y., Jun 15 1996, In : Journal of Physiology. 493, 3, p. 785-791 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
1995

Aplyparvunin, a bioactive acetogenin from the sea hare Aplysia parvula

Miyamoto, T., Ebisawa, Y. & Higuchi, R., Aug 21 1995, In : Tetrahedron Letters. 36, 34, p. 6073-6074 2 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Bioactive diterpenoids from octocorallia, 2. deoxyxeniolide B, a novel ichthyotoxic diterpenoid from the soft coral xenia elongata

Miyamoto, T., Takenaka, Y., Yamada, K. & Higuchi, R., Jun 1995, In : Journal of Natural Products. 58, 6, p. 924-928 5 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Biochemical characterization of liver microsomal, golgi, lysosomal, and serum β-glucuronidases in dibuty1 phosphate-treated rats

Nishimura, Y., Kato, K. & Himeno, M., Jan 1 1995, In : Journal of biochemistry. 118, 1, p. 56-66 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Biochemical Properties and Intracellular Processing of Lysosomal Cathepsins B and H

Nishimura, Y., Tsuji, H., Kato, K., Sato, H., Amano, J., Himeno, M. & Tsuji, H., Jan 1 1995, In : Biological and Pharmaceutical Bulletin. 18, 6, p. 829-836 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Biosynthesis, processing, and lysosome targeting of acid phosphatase

Himeno, M. & Tanaka, Y., Jan 1 1995, In : Nippon rinsho. Japanese journal of clinical medicine. 53, 12, p. 2898-2903 6 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Biosynthesis and Processing of Lysosomal Cathepsin D in Primary Cultures of Rat Hepatocytes

Nishimura, Y., Kato, K., Himeno, M. & Koji, F., Jan 1 1995, In : Biological and Pharmaceutical Bulletin. 18, 6, p. 825-828 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Cannabinerolic acid, a cannabinoid from Cannabis sativa

Taura, F., Morimoto, S. & Shoyama, Y., Jan 1 1995, In : Phytochemistry. 39, 2, p. 457-458 2 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Cathepsin D associates with lysosomal membranous protein

Nishimura, Y. & Himeno, M., Jan 1 1995, In : Biological and Pharmaceutical Bulletin. 18, 10, p. 1340-1346 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Characterization of Escherichia coli DnaAcos protein in replication systems reconstituted with highly purified proteins

Katayama, T., Crooke, E. & Sekimizu, K., Dec 1995, In : Molecular Microbiology. 18, 5, p. 813-820 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Correlation between the differences in the free energy change and conformational energy in the folded state of hen lysozymes with gly-pro and pro-gly sequences introduced to the same site

Motoshima, H., Ueda, T., Hashimoto, Y., Tsutsumi, M. & Imoto, T., Dec 1995, In : Journal of biochemistry. 118, 6, p. 1138-1144 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Effective renaturation of reduced lysozyme by gentle removal of urea

Maeda, Y., Koga, H., Yamada, H., Ueda, T. & Imoto, T., Feb 1 1995, In : Protein Engineering, Design and Selection. 8, 2, p. 201-205 5 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Effect of a coplanar PCB on lipid metabolism: the remarkable difference between rats and guinea pigs

Hatsumura, M., Ishida, T., Ishii, Y., Ariyoshi, N., Oguri, K. & Yoshimura, H., Jan 1 1995, In : Fukuoka igaku zasshi = Hukuoka acta medica. 86, 5, p. 135-143 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Effect of salt concentration on the pKa of acidic residues in lysozyme

Abe, Y., Ueda, T., Iwashita, H., Hashimoto, Y., Motoshima, H., Tanaka, Y. & Imoto, T., Oct 1995, In : Journal of biochemistry. 118, 5, p. 946-952 7 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Expression of rat cathepsin D cDNA in Saccharomyces cerevisiae: Intracellular sorting of cathepsin D to yeast vacuole

Nishimura, Y., Fujita, H., Kato, K. & Himeno, M., 1995, In : Advances in experimental medicine and biology. 362, p. 289-292 4 p.

Research output: Contribution to journalArticle

Expression of rat cathepsin D cDNA in Saccharomyces cerevisiae: Implications for intracellular targeting of cathepsin D to vacuoles

Nishimura, Y., Takeshima, H., Sakaguchi, M., Mihara, K., Omura, T., Kato, K. & Himeno, M., Jul 1995, In : Journal of biochemistry. 118, 1, p. 168-177 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)