Research Output

Forced retraction of spinal root injury enhances activation of p38 MAPK cascade in infiltrating macrophages

Nomura, H., Furuta, A., Tanaka, Y. & Iwaki, T., Mar 1 2005, In : Neuropathology. 25, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Formation of a monoclonal antibody against glycyrrhizin and development of an ELISA

Tanaka, H. & Shoyama, Y., Jan 1 1998, In : Biological and Pharmaceutical Bulletin. 21, 12, p. 1391-1393 3 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Formation of an ATP-DnaA-specific initiation complex requires DnaA arginine 285, a conserved motif in the AAA+ protein family

Kawakamii, H., Keyamura, K. & Katayama, T., Jul 22 2005, In : Journal of Biological Chemistry. 280, 29, p. 27420-27430 11 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Formation of ginsenoside-protein conjugates

Park, H., Shoyama, Y., Xuan, L. J. & Tanaka, H., Dec 1 1999, In : Studies in Plant Science. 6, C, p. 83-86 4 p.

Research output: Contribution to journalArticle

Formation of highly analgesic morphine-6-glucuronide following physiologic concentration of morphine in human brain

Yamada, H., Ishii, K., Ishii, Y., Ieiri, I., Nishio, S., Morioka, T. & Oguri, K., Dec 1 2003, In : Journal of Toxicological Sciences. 28, 5, p. 395-401 7 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Formation of monoclonal antibody against a major ginseng component, ginsenoside Rb1 and its characterization

Tanaka, H., Fukuda, N. & Shoyama, Y., Jan 1 1999, In : Cytotechnology. 29, 2, p. 115-120 6 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Formation of monoclonal antibody against a major ginseng component, ginsenoside Rg1 and its characterization: Monoclonal antibody for a ginseng saponin

Fukuda, N., Tanaka, H. & Shoyama, Y., Jan 1 2000, In : Cytotechnology. 34, 3, p. 197-204 8 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Formation of monoclonal antibody against naturally occurring biologically active compounds and their application

Tanaka, H., Jun 1 2000, In : Natural Medicines. 54, 3, p. 123-128 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Formation of α-helix 88-98 is essential in the establishment of higher-order structure from reduced lysozyme

Ueda, T., Nakashima, A., Hashimoto, Y., Miki, T., Yamada, H. & Imoto, T., Jan 27 1994, In : Journal of Molecular Biology. 235, 4, p. 1312-1317 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Four new cembrane diterpenes isolated from an Okinawan soft coral Lobophytum crassum with inhibitory effects on nitric oxide production

Wanzola, M., Furuta, T., Kohno, Y., Fukumitsu, S., Yasukochi, S., Watari, K., Tanaka, C., Higuchi, R. & Miyamoto, T., Sep 1 2010, In : Chemical and Pharmaceutical Bulletin. 58, 9, p. 1203-1209 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Functional analysis of CedA based on its structure: Residues important in binding of DNA and RNA polymerase and in the cell division regulation

Abe, Y., Fujisaki, N., Miyoshi, T., Watanabe, N., Katayama, T. & Ueda, T., May 13 2015, In : Journal of biochemistry. 159, 2, p. 217-223 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Functional characterization of Val60, a key residue involved in the membrane-oligomerization of fragaceatoxin C, an actinoporin from Actinia fragacea

Morante, K., Caaveiro, J. M. M., Viguera, A. R., Tsumoto, K. & González-Mañas, J. M., 2015, In : FEBS Letters. 589, p. 1840-1846 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane

Rujas, E., Insausti, S., García-Porras, M., Sánchez-Eugenia, R., Tsumoto, K., Nieva, J. L. & Caaveiro, J. M. M., Apr 21 2017, In : Journal of Molecular Biology. 429, 8, p. 1213-1226 14 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Functional induction and de-induction of P-glycoprotein by St. John's wort and its ingredients in a human colon adenocarcinoma cell line

Tian, R., Koyabu, N., Morimoto, S., Shoyama, Y., Ohtani, H. & Sawada, Y., Apr 1 2005, In : Drug Metabolism and Disposition. 33, 4, p. 547-554 8 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Functional protein-protein interaction of drug metabolizing enzymes.

Ishii, Y., Takeda, S., Yamada, H. & Oguri, K., Jan 1 2005, In : Frontiers in bioscience : a journal and virtual library. 10, p. 887-895 9 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Furostane-type steroidal saponins from the roots of Chlorophytum borivilianum

Acharya, D., Mitaine-Offer, A. C., Kaushik, N., Miyamoto, T., Paululat, T. & Lacaille-Dubois, M. A., Dec 1 2008, In : Helvetica Chimica Acta. 91, 12, p. 2262-2269 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Gemcitabine induces Parkin-independent mitophagy through mitochondrial-resident E3 ligase MUL1-mediated stabilization of PINK1

Igarashi, R., Yamashita, S-I., Yamashita, T., Inoue, K., Fukuda, T., Fukuchi, T. & Kanki, T., Jan 30 2020, In : Scientific reports. 10, 1, p. 1465

Research output: Contribution to journalArticle

Generation of a monoclonal antibody for INI1/hSNF5/BAF47

Harada, A., Hayashi, M., Kuniyoshi, Y., Semba, Y., Sugahara, S., Tachibana, T., Ohkawa, Y. & Fujita, M., Feb 1 2014, In : Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33, 1, p. 49-51 3 p.

Research output: Contribution to journalArticle

Gene Therapy for Hepatoma Cells Using a Retrovirus Vector Carrying Herpes Simplex Virus Thymidine Kinase Gene under the Control of Human α-Fetoprotein Gene Promoter

Ido, A., Nakata, K., Kato, Y., Nakao, K., Murata, K., Fujita, M., Ishii, N., Tamaoki, T., Shiku, H. & Nagataki, S., Jul 15 1995, In : Cancer Research. 55, 14, p. 3105-3109 5 p.

Research output: Contribution to journalArticle

168 Citations (Scopus)

Genetic and alkaloid analysis of Papaver species and their F1 hybrid by RAPD, HPLC and ELISA

Shoyama, Y., Kawachi, F., Tanaka, H., Nakai, R., Shibata, T. & Nishi, K., Feb 16 1998, In : Forensic Science International. 91, 3, p. 207-217 11 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Genetic background of Japanese thrombophilia

Hamasaki, N., Kinoshita, S. & Abe, Y., Nov 2002, In : Rinsho byori. The Japanese journal of clinical pathology. Suppl 123, p. 104-111 8 p.

Research output: Contribution to journalReview article

Genetic variability of the major histocompatibility complex class I homologue encoded by human cytomegalovirus leads to differential binding to the inhibitory receptor ILT2

Valés-Gómez, M., Shiroishi, M., Maenaka, K. & Reyburn, H. T., Feb 2005, In : Journal of virology. 79, 4, p. 2251-2260 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Genetic variants of IL-13 signalling and human asthma and atopy

Heinzmann, A., Mao, X. Q., Akaiwa, M., Kreomer, R. T., Gao, P. S., Ohshima, K., Umeshita, R., Abe, Y., Braun, S., Yamashita, T., Roberts, M. H., Sugimoto, R., Arima, K., Arinobu, Y., Yu, B., Kruse, S., Enomoto, T., Dake, Y., Kawai, M., Shimazu, S. & 12 others, Sasaki, S., Adra, C. N., Kitaichi, M., Inoue, H., Yamauchi, K., Tomichi, N., Kurimoto, F., Hamasaki, N., Hopkin, J. M., Izuhara, K., Shirakawa, T. & Deichmann, K. A., Mar 1 2000, In : Human Molecular Genetics. 9, 4, p. 549-559 11 p.

Research output: Contribution to journalArticle

372 Citations (Scopus)

Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., Jul 27 2018, In : Nucleic Acids Research. 46, 13, p. 6683-6696 14 p.

Research output: Contribution to journalArticle

Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., Jan 1 2018, In : Nucleic acids research. 46, 13, p. 6683-6696 14 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Gestational dioxin exposure suppresses prolactin-stimulated nursing in lactating dam rats to impair development of postnatal offspring

Takeda, T., Fujii, M., Izumoto, W., Hattori, Y., Matsushita, T., Yamada, H. & Ishii, Y., Aug 2020, In : Biochemical Pharmacology. 178, 114106.

Research output: Contribution to journalArticle

Glandulosides A-D, triterpene saponins from Acanthophyllum glandulosum

Gaidi, G., Miyamoto, T., Ramezani, M. & Lacaille-Dubois, M. A., Jul 1 2004, In : Journal of Natural Products. 67, 7, p. 1114-1118 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Glaucasides A-C, three saikosaponins from Atriplex glauca L. var. ifiniensis (Caball) Maire

Jabrane, A., Ben Jannet, H., Miyamoto, T., Tanaka, C., Mirjolet, J. F., Duchamp, O., Harzallah-Skhiri, F. & Lacaille-Dubois, M. A., Feb 2011, In : Magnetic Resonance in Chemistry. 49, 2, p. 83-89 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Glucuronidation and the UDP-glucuronosyltransferases in health and disease

Wells, P. G., Mackenzie, P. I., Chowdhury, J. R., Guillemette, C., Gregory, P. A., Ishii, Y., Hansen, A. J., Kessler, F. K., Kim, P. M., Chowdhury, N. R. & Ritter, J. K., Mar 1 2004, In : Drug Metabolism and Disposition. 32, 3, p. 281-290 10 p.

Research output: Contribution to journalArticle

191 Citations (Scopus)

Glucuronide triterpene saponins from Bersama engleriana

Tapondjou, A. L., Miyamoto, T. & Lacaille-Dubois, M. A., Oct 1 2006, In : Phytochemistry. 67, 19, p. 2126-2132 7 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2 Citations (Scopus)

Glycosylation of IgG-Fc: A molecular perspective

Kiyoshi, M., Tsumoto, K., Ishii-Watabe, A. & Caaveiro, J. M. M., Jul 1 2017, In : International immunology. 29, 7, p. 311-317 7 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)

Green Pharma: A new strategy for drug discovery in academia by targeting glial cells and ATP receptors

Yamashita, T., Makoto, T., Saitoh, H. & Inoue, K., Jan 1 2018, In : Yakugaku Zasshi. 138, 8, p. 1027-1031 5 p.

Research output: Contribution to journalReview article

GRWD1, a new player among oncogenesis-related ribosomal/nucleolar proteins

Takafuji, T., Kayama, K., Sugimoto, N. & Fujita, M., Aug 3 2017, In : Cell Cycle. 16, 15, p. 1397-1403 7 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)

GRWD1 directly interacts with p53 and negatively regulates p53 transcriptional activity

Fujiyama, H., Tsuji, T., Hironaka, K., Yoshida, K., Sugimoto, N. & Fujita, M., Jan 1 2020, In : Journal of biochemistry. 167, 1, p. 15-24 10 p.

Research output: Contribution to journalArticle

GRWD1 negatively regulates p53 via the RPL11–MDM2 pathway and promotes tumorigenesis

Kayama, K., Watanabe, S., Takafuji, T., Tsuji, T., Hironaka, K., Matsumoto, M., Nakayama, K. I., Enari, M., Kohno, T., Shiraishi, K., Kiyono, T., Yoshida, K., Sugimoto, N. & Fujita, M., Jan 1 2017, In : EMBO Reports. 18, 1, p. 123-137 15 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, K. I., Yoshida, K., Sugimoto, N. & Fujita, M., Aug 1 2018, In : Journal of cell science. 131, 15

Research output: Contribution to journalArticle

5 Citations (Scopus)

Guest-Induced Conformational Change of 6-Monosubstituted Cyclodextrin

Fujita, K., Ueda, T., Matsunaga, A. & Imoto, T., Jan 1 1983, In : NIPPON KAGAKU KAISHI. 1983, 2, p. 207-213 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Guest-induced conformational change of β-cyclodextrin capped with an environmentally sensitive chromophore

Fujita, K., Ueda, T., Imoto, T., Tabushi, I., Toh, N. & Koga, T., Mar 1982, In : Bioorganic Chemistry. 11, 1, p. 72-84 13 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Hda, a novel DnaA-related protein, regulates the replication cycle in Escherichia coli

Kato, J. I. & Katayama, T., Aug 1 2001, In : EMBO Journal. 20, 15, p. 4253-4262 10 p.

Research output: Contribution to journalArticle

199 Citations (Scopus)

Hda monomerization by ADP binding promotes replicase clamp-mediated DnaA-ATP hydrolysis

Su'etsugu, M., Nakamura, K., Keyamura, K., Kudo, Y. & Katayama, T., Dec 26 2008, In : Journal of Biological Chemistry. 283, 52, p. 36118-36131 14 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Hederagenin glycosides from the fruits of Blighia unijugata

Petit, B., Mitaine-Offer, A. C., Delaude, C., Miyamoto, T., Tanaka, C. & Lacaille-Dubois, M. A., Jun 1 2019, In : Phytochemistry. 162, p. 260-269 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Helical image reconstruction of the outward-open human erythrocyte band 3 membrane domain in tubular crystals

Yamaguchi, T., Fujii, T., Abe, Y., Hirai, T., Kang, D., Namba, K., Hamasaki, N. & Mitsuoka, K., Mar 1 2010, In : Journal of structural biology. 169, 3, p. 406-412 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Helicase and its interacting factors: Regulation mechanism, characterization, structure, and application for drug design

Huang, C. Y., Abe, Y., Ding, H. & Chung, I. F., Jan 1 2015, In : BioMed Research International. 2015, 909047.

Research output: Contribution to journalEditorial

Heterocomplex formation by Arp4 and β-actin is involved in the integrity of the Brg1 chromatin remodeling complex

Nishimoto, N., Watanabe, M., Watanabe, S., Sugimoto, N., Yugawa, T., Ikura, T., Koiwai, O., Kiyono, T. & Fujita, M., Aug 15 2012, In : Journal of Cell Science. 125, 16, p. 3870-3882 13 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Heterogeneous packing in the folding/unfolding intermediate state of bitter gourd trypsin inhibitor

Takahashi, D., Matsumoto, S., Nishimoto, E., Otosu, T. & Yamashita, S., Jul 1 2008, In : Bioscience, Biotechnology and Biochemistry. 72, 6, p. 1498-1505 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT

Miyauchi, Y., Kurita, A., Yamashita, R., Takamatsu, T., Ikushiro, S., Mackenzie, P. I., Tanaka, Y. & Ishii, Y., Apr 30 2020, In : Biochemical and Biophysical Research Communications. 525, 2, p. 348-353 6 p.

Research output: Contribution to journalArticle

Heterooligomer of type 1 and type 2 inositol 1, 4, 5-trisphosphate receptor expressed in rat liver membrane fraction exists as tetrameric complex

Onoue, H., Tanaka, H., Tanaka, K., Doira, N. & Ito, Y., Jan 27 2000, In : Biochemical and Biophysical Research Communications. 267, 3, p. 928-933 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

High-level expression of uniformly 15N-labeled hen lysozyme in Pichia pastoris and identification of the site in hen lysozyme where phosphate ion binds using NMR measurements

Mine, S., Ueda, T., Hashimoto, Y., Tanaka, Y. & Imoto, T., Apr 2 1999, In : FEBS Letters. 448, 1, p. 33-37 5 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Highly controlled carbodiimide reaction for the modification of lysozyme. Modification of leu129 or asp119

Ueda, T., Yamada, H. & Imoto, T., Jun 1 1987, In : Protein Engineering, Design and Selection. 1, 3, p. 189-193 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)