Research Output

Inducing ability of co-planar PCBs toward bilirubin UDP-glucuronyltransferase of liver microsomes: the remarkable difference between guinea pigs and rats

Oguri, K., Koga, Y., Tsuda, M., Ariyoshi, N., Ishii, Y., Yamada, H. & Yoshimura, H., Jan 1 1993, In : Fukuoka igaku zasshi = Hukuoka acta medica. 84, 5, p. 175-180 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Induction of a cytosolic 54 kDa protein in rat liver that is highly homologous to selenium-binding protein

Ishida, T., Tasaki, K., Fukuda, A., Ishii, Y. & Oguri, K., Dec 1 1998, In : Environmental Toxicology and Pharmacology. 6, 4, p. 249-255 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Induction of bilirubin UDP-glucuronyltransferase and CYP4A1 P450 by co-planar PCBs: Different responsiveness of guinea pigs and rats

Koga, Y., Tsuda, M., Ariyoshi, N., Ishii, Y., Yamada, H., Oguri, K., Funae, Y. & Yoshimura, H., Feb 1994, In : Chemosphere. 28, 3, p. 639-645 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Induction of bilirubin UDP-glucuronyltransferase and P-450 4A subfamily in guinea pigs by treatment with coplanar PCB

Koga, Y., Tsuda, M., Ariyoshi, N., Ishii, Y., Yamada, H., Oguri, K., Yoshimura, H. & Funae, Y., 1993, In : Japanese Journal of Toxicology and Environmental Health. 39, 1

Research output: Contribution to journalArticle

Induction of molecular chaperones HSP70 and HSP90 in rat liver cytosol by a highly toxic coplanar PCB

Fukuda, A., Ishii, Y., Tasaki, K., Matsusue, K., Ishida, T. & Oguri, K., 1999, In : Fukuoka Acta Medica. 90, 5, p. 259-271 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Induction of the hepatic cytochrome P450 2B subfamily by xenobiotics: Research history, evolutionary aspect, relation to tumorigenesis, and mechanism

Yamada, H., Ishii, Y., Yamamoto, M. & Oguri, K., May 1 2006, In : Current Drug Metabolism. 7, 4, p. 397-409 13 p.

Research output: Contribution to journalReview article

32 Citations (Scopus)

Influence of cluster formation of acidic phospholipids on decrease in the affinity for ATP of DnaA protein

Mizushima, T., Ishikawa, Y., Obana, E., Hase, M., Kubota, T., Katayama, T., Kunitake, T., Watanabe, E. & Sekimizu, K., Feb 16 1996, In : Journal of Biological Chemistry. 271, 7, p. 3633-3638 6 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Influence of hydrogen and frequency on fatigue crack growth behavior of Cr-Mo steel

Matsuoka, S., Tanaka, H., Homma, N. & Murakami, Y., Mar 1 2011, In : International Journal of Fracture. 168, 1, p. 101-112 12 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Influence of mutations of the N-cap residue, Gly4, on stability and structure of hen lysozyme

Motoshima, H., Ueda, T., Masumoto, K., Hashimoto, Y., Chijiiwa, Y. & Imoto, T., Jul 1997, In : Journal of biochemistry. 122, 1, p. 25-31 7 p.

Research output: Contribution to journalArticle

Influence of seasons, different plant parts, and plant growth stages on saponin quantity and distribution in Bacopa monnieri

Phrompittayarat, W., Jetiyanon, K., Wittaya-Areekul, S., Putalun, W., Tanaka, H., Khan, I. & Ingkaninan, K., Aug 22 2011, In : Songklanakarin Journal of Science and Technology. 33, 2, p. 193-199 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Inhibiting the MCM8-9 complex selectively sensitizes cancer cells to cisplatin and olaparib

Morii, I., Iwabuchi, Y., Mori, S., Suekuni, M., Natsume, T., Yoshida, K., Sugimoto, N., Kanemaki, M. T. & Fujita, M., Mar 2019, In : Cancer Science. 110, 3, p. 1044-1053 10 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Inhibition of amyloid fibril formation in the variable domain of λ6 light chain mutant Wil caused by the interaction between its unfolded state and epigallocatechin-3-O-gallate

Abe, Y., Odawara, N., Aeimhirunkailas, N., Shibata, H., Fujisaki, N., Tachibana, H. & Ueda, T., Dec 2018, In : Biochimica et Biophysica Acta - General Subjects. 1862, 12, p. 2570-2578 9 p.

Research output: Contribution to journalArticle

Inhibition of amyloid fibril formation in the variable domain of λ6 light chain mutant Wil caused by the interaction between its unfolded state and epigallocatechin-3-O-gallate

Abe, Y., Odawara, N., Aeimhirunkailas, N., Shibata, H., Fujisaki, N., Tachibana, H. & Ueda, T., Dec 2018, In : Biochimica et Biophysica Acta - General Subjects. 1862, 12, p. 2570-2578 9 p.

Research output: Contribution to journalArticle

Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease

Matsunaga, N., Ikeda, E., Kakimoto, K., Watanabe, M., Shindo, N., Tsuruta, A., Ikeyama, H., Hamamura, K., Higashi, K., Yamashita, T., Kondo, H., Yoshida, Y., Matsuda, M., Ogino, T., Tokushige, K., Itcho, K., Furuichi, Y., Nakao, T., Yasuda, K., Doi, A. & 7 others, Amamoto, T., Aramaki, H., Tsuda, M., Inoue, K., Ojida, A., Koyanagi, S. & Ohdo, S., Nov 1 2016, In : EBioMedicine. 13, p. 262-273 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Inhibition of intracellular sorting and processing of lysosomal cathepsins H and L at reduced temperature in primary cultures of rat hepatocytes

Nishimura, Y., Kawabata, T., Yano, S. & Kato, K., Jan 1 1990, In : Archives of Biochemistry and Biophysics. 283, 2, p. 458-463 6 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Inhibition of morphine glucuronidation in the liver microsomes of rats and humans by monoterpenoid alcohols

Ishii, Y., Iida, N., Miyauchi, Y., Mackenzie, P. I. & Yamada, H., Oct 1 2012, In : Biological and Pharmaceutical Bulletin. 35, 10, p. 1811-1817 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Inhibition of P-glycoprotein by orange juice components, polymethoxyflavones in adriamycin-resistant human myelogenous leukemia (K562/ADM) cells

Ikegawa, T., Ushigome, F., Koyabu, N., Morimoto, S., Shoyama, Y., Naito, M., Tsuruo, T., Ohtani, H. & Sawada, Y., Nov 10 2000, In : Cancer Letters. 160, 1, p. 21-28 8 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

Inhibition of S-Phase Cyclin-Dependent Kinase Activity Blocks Expression of Epstein-Barr Virus Immediate-Early and Early Genes, Preventing Viral Lytic Replication

Kudoh, A., Daikoku, T., Sugaya, Y., Isomura, H., Fujita, M., Kiyono, T., Nishiyama, Y. & Tsurumi, T., Jan 2004, In : Journal of virology. 78, 1, p. 104-115 12 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Inhibition of UDP-glucuronosyltransferase 2B7-catalyzed morphine glucuronidation by ketoconazole: Dual mechanisms involving a novel noncompetitive mode

Takeda, S., Kitajima, Y., Ishii, Y., Nishimura, Y., Mackenzie, P. I., Oguri, K. & Yamada, H., 2006, In : Drug Metabolism and Disposition. 34, 8, p. 1277-1282 6 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Inhibitory Effect of Ethanol and Colchicine on the Intracellular Processing of β-Glucuronidase Which Occurs in the Golgi Complex

Nishimura, Y., Kato, K., Himeno, M. & Oda, K., Jan 1 1995, In : Biological and Pharmaceutical Bulletin. 18, 7, p. 938-944 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Inhibitory Effect of Leupeptin on the Intracellular Maturation of Lysosomal Cathepsin L in Primary Cultures of Rat Hepatocytes

Nishimura, Y., Kato, K., Himeno, M. & Furuno, K., Jan 1 1995, In : Biological and Pharmaceutical Bulletin. 18, 7, p. 945-950 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Inhibitory effect of norditerpenes on LPS-induced TNF-α production from the Okinawan soft coral, Sinularia sp.

Takaki, H., Koganemaru, R., Iwakawa, Y., Higuchi, R. & Miyamoto, T., Jan 1 2003, In : Biological and Pharmaceutical Bulletin. 26, 3, p. 380-382 3 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Inhibitory effects of 16-hydroxy-9-oxo-10E,12E,14E-octadecatrienoic acid (Corchorifatty acid B) isolated from Melissa officinalis Linné on melanogenesis

Fujita, H., Hongo, M., Mochizuki, M., Yokoyama, K. & Tanaka, Y., May 1 2011, In : Experimental Dermatology. 20, 5, p. 420-424 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Inhibitory effects of adenine nucleotides and related substances on UDP-glucuronosyltransferase: Structure-effect relationships and evidence for an allosteric mechanism

Nishimura, Y., Maeda, S., Ikushiro, S. I., Mackenzie, P. I., Ishii, Y. & Yamada, H., Nov 1 2007, In : Biochimica et Biophysica Acta - General Subjects. 1770, 11, p. 1557-1566 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Inhibitory effects of SSRIs on IFN-γ induced microglial activation through the regulation of intracellular calcium

Horikawa, H., Kato, T. A., Mizoguchi, Y., Monji, A., Seki, Y., Ohkuri, T., Gotoh, L., Yonaha, M., Ueda, T., Hashioka, S. & Kanba, S., Oct 1 2010, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 34, 7, p. 1306-1316 11 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)
26 Citations (Scopus)

Initiation of DNA replication at the chromosomal origin of E. coli, oriC

Katayama, T., Jan 1 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 79-98 20 p. (Advances in Experimental Medicine and Biology; vol. 1042).

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Citations (Scopus)
1 Citation (Scopus)

Interaction between cytochrome P450 and other drug-metabolizing enzymes: Evidence for an association of CYP1A1 with microsomal epoxide hydrolase and UDP-glucuronosyltransferase

Taura, K. I., Yamada, H., Hagino, Y., Ishii, Y., Mori, M. A. & Oguri, K., Jul 14 2000, In : Biochemical and Biophysical Research Communications. 273, 3, p. 1048-1052 5 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Interaction of cytochrome P450 3A4 and UDP-glucuronosyltransferase 2B7: Evidence for protein-protein association and possible involvement of CYP3A4 J-helix in the interaction

Takeda, S., Ishii, Y., Iwanaga, M., Nurrochmad, A., Ito, Y., Mackenzie, P. I., Nagata, K., Yamazoe, Y., Oguri, K. & Yamada, H., Apr 1 2009, In : Molecular Pharmacology. 75, 4, p. 956-964 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Interaction of saposins, acidic lipids, and glucosylceramidase

Morimoto, S., Kishimoto, Y., Tomich, J., Weiler, S., Ohashi, T., Barranger, J. A., Kretz, K. A. & O'Brien, J. S., Feb 5 1990, In : Journal of Biological Chemistry. 265, 4, p. 1933-7 5 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Intracellular dynamics and fate of a humanized anti-interleukin-6 receptor monoclonal antibody, Tocilizumab

Fujimoto, K., Ida, H., Hirota, Y., Ishigai, M., Amano, J. & Tanaka, Y., Oct 1 2015, In : Molecular Pharmacology. 88, 4, p. 660-675 16 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Intracellular logistics of BST-2/Tetherin

Fujita, H., Fujimoto, K., Tokunaga, K. & Tanaka, Y., Jun 2012, In : Current HIV Research. 10, 4, p. 321-326 6 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity

Nagata, M., Izumi, Y., Ishikawa, E., Kiyotake, R., Doi, R., Iwai, S., Omahdi, Z., Yamaji, T., Miyamoto, T., Bamba, T. & Yamasaki, S., Apr 18 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 16, p. E3285-E3294

Research output: Contribution to journalArticle

39 Citations (Scopus)

Intracellular sorting of lysosomal β-glucuronidase is altered due to administaration of dibutyl phosphate

Nishimura, Y., Kato, K., Oda, K., Ishikawa, T., Ikehara, Y. & Himeno, M., Jan 1 1995, In : Journal of biochemistry. 118, 1, p. 46-55 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Intracellular targeting of lysosomal cathepsin D in COS cells

Takeshima, H., Sakaguchi, M., Mihara, K., Murakami, K., Omura, T., Himeno, M. & Nishimura, Y., Oct 1 1995, In : Journal of biochemistry. 118, 5, p. 981-988 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Intracellular transport and processing of lysosomal cathepsin B

Nishimura, Y. & Kato, K., Oct 14 1987, In : Biochemical and Biophysical Research Communications. 148, 1, p. 254-259 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Intracellular transport and processing of lysosomal cathepsin H

Nishimura, Y. & Kato, K., Oct 14 1987, In : Biochemical and Biophysical Research Communications. 148, 1, p. 329-334 6 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody

Miyanabe, K., Akiba, H., Kuroda, D., Nakakido, M., Kusano-Arai, O., Iwanari, H., Hamakubo, T., Caaveiro, J. M. M. & Tsumoto, K., Jul 1 2018, In : Journal of biochemistry. 164, 1, p. 65-76 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Intrinsic nuclear import activity of geminin is essential to prevent re-initiation of DNA replication in Xenopus eggs

Yoshida, K., Takisawa, H. & Kubota, Y., Jan 2005, In : Genes to Cells. 10, 1, p. 63-73 11 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Introduction of a glycosylation site in the constant region decreases the aggregation of adalimumab Fab

Nakamura, H., Oda-Ueda, N., Ueda, T. & Ohkuri, T., Sep 5 2018, In : Biochemical and Biophysical Research Communications. 503, 2, p. 752-756 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Introduction of an N-glycosylation site into UDP-glucuronosyltransferase 2B3 alters its sensitivity to cytochrome P450 3A1-dependent modulation

Nakamura, T., Yamaguchi, N., Miyauchi, Y., Takeda, T., Yamazoe, Y., Nagata, K., Mackenzie, P. I., Yamada, H. & Ishii, Y., Nov 14 2016, In : Frontiers in Pharmacology. 7, NOV, 427.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Inulavosin, a melanogenesis inhibitor, leads to mistargeting of tyrosinase to lysosomes and accelerates its degradation

Fujita, H., Motokawa, T., Katagiri, T., Yokota, S., Yamamoto, A., Himeno, M. & Tanaka, Y., Jun 2009, In : Journal of Investigative Dermatology. 129, 6, p. 1489-1499 11 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Inulavosin and its benzo-derivatives, melanogenesis inhibitors, target the copper loading mechanism to the active site of tyrosinase

Fujita, H., Menezes, J. C. J. M. D. S., Santos, S. M., Yokota, S., Kamat, S. P., Cavaleiro, J. A. S., Motokawa, T., Kato, T., Mochizuki, M., Fujiwara, T., Fujii, Y. & Tanaka, Y., May 2014, In : Pigment Cell and Melanoma Research. 27, 3, p. 376-386 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Investigation of the endoplasmic reticulum localization of UDP-glucuronosyltransferase 2B7 with systematic deletion mutants

Miyauchi, Y., Kimura, S., Kimura, A., Kurohara, K., Hirota, Y., Fujimoto, K., Mackenzie, P. I., Tanaka, Y. & Ishii, Y., May 2019, In : Molecular Pharmacology. 95, 5, p. 551-562 12 p.

Research output: Contribution to journalArticle

Investigation of the structural basis for thermostability of DNA- binding protein HU from Bacillus stearothermophilus

Kawamura, S., Abe, Y., Ueda, T., Masumoto, K., Imoto, T., Yamasaki, N. & Kimura, M., Aug 7 1998, In : Journal of Biological Chemistry. 273, 32, p. 19982-19987 6 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

In vitro binding study of adaptor protein complex (AP-1) to lysosomal targeting motif (LI-motif)

Fujita, H., Saeki, M., Yasunaga, K., Ueda, T., Imoto, T. & Himeno, M., Feb 5 1999, In : Biochemical and Biophysical Research Communications. 255, 1, p. 54-58 5 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

In vitro biosynthesis of the lysosomal cathepsin H

Nishimura, Y. & Kato, K., Jul 15 1987, In : Biochemical and Biophysical Research Communications. 146, 1, p. 159-164 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Involvement of COX-1 and up-regulated prostaglandin e synthases in phosphatidylserine liposome-induced prostaglandin E2 production by microglia

Zhang, J., Fujii, S., Wu, Z., Hashioka, S., Tanaka, Y., Shiratsuchi, A., Nakanishi, Y. & Nakanishi, H., Mar 1 2006, In : Journal of Neuroimmunology. 172, 1-2, p. 112-120 9 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
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