Research Output

Structural analysis of the histamine H1 receptor

Shiroishi, M. & Kobayashi, T., Jan 1 2017, Handbook of Experimental Pharmacology. Springer New York LLC, p. 21-30 10 p. (Handbook of Experimental Pharmacology; vol. 241).

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Structural and In Vitro Functional Analyses of Novel Plant-Produced Anti-Human PD1 Antibody

Rattanapisit, K., Phakham, T., Buranapraditkun, S., Siriwattananon, K., Boonkrai, C., Pisitkun, T., Hirankarn, N., Strasser, R., Abe, Y. & Phoolcharoen, W., Dec 1 2019, In : Scientific reports. 9, 1, 15205.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Structural and thermodynamic characterization of the self-adhesive properties of human P-cadherin

Kudo, S., Caaveiro, J. M. M., Miyafusa, T., Goda, S., Ishii, K., Matsuura, T., Sudou, Y., Kodama, T., Hamakubo, T. & Tsumoto, K., 2012, In : Molecular BioSystems. 8, p. 2050-2053 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface.

Rujas, E., Caaveiro, J. M. M., Partida-Hanon, A., Gulzar, N., Morante, K., Apellaniz, B., García-Porras, M., Bruix, M., Tsumoto, K., Scott, J. K., Jimenez, M. A. & Nieva, J. L., 2016, In : Scientific Reports. 6, 13 p., 38177.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)

Shiroishi, M., Kuroki, K., Rasubala, L., Tsumoto, K., Kumagai, I., Kurimoto, E., Kato, K., Kohda, D. & Maenaka, K., Oct 31 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 44, p. 16412-16417 6 p.

Research output: Contribution to journalArticle

174 Citations (Scopus)

Structural basis of replication origin recognition by the DnaA protein

Fujikawa, N., Kurumizaka, H., Nureki, O., Terada, T., Shirouzu, M., Katayama, T. & Yokoyama, S., Apr 15 2003, In : Nucleic acids research. 31, 8, p. 2077-2086 10 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)

Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex: The case of HyHEL-10-HEL

Shiroishi, M., Tsumoto, K., Tanaka, Y., Yokota, A., Nakanishi, T., Kondo, H. & Kumagai, I., Mar 2 2007, In : Journal of Biological Chemistry. 282, 9, p. 6783-6791 9 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Structural elucidation of the ceramide moiety of starfish gangliosides by collision-induced dissociation of the sodium ion complex

Inagaki, M., Isobe, R., Miyamoto, T. & Higuchi, R., Jan 1 1999, In : Chemical and Pharmaceutical Bulletin. 47, 8, p. 1184-1187 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction. The case of hen lysozyme-HyHEL-10 Fv complex

Shiroishi, M., Yokota, A., Tsumoto, K., Kondo, H., Nishimiya, Y., Horii, K., Matsushima, M., Ogasahara, K., Yutani, K. & Kumagai, I., Jun 22 2001, In : Journal of Biological Chemistry. 276, 25, p. 23042-23050 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Structure, synthesis, and biological activity of a C-20 bisacetylenic alcohol from a marine sponge Callyspongia sp.

Shirouzu, T., Watari, K., Ono, M., Koizumi, K., Saiki, I., Tanaka, C., Van Soest, R. W. M. & Miyamoto, T., Jul 26 2013, In : Journal of Natural Products. 76, 7, p. 1337-1342 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Structure and cytotoxicity of steroidal glycosides from Allium schoenoprasum

Timité, G., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Mirjolet, J. F., Duchamp, O. & Lacaille-Dubois, M. A., Apr 1 2013, In : Phytochemistry. 88, p. 61-66 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Structure and function of DnaA N-terminal domains: Specific sites and mechanisms in inter-DnaA interaction and in DnaB helicase loading on oriC

Abe, Y., Jo, T., Matsuda, Y., Matsunaga, C., Katayama, T. & Ueda, T., Jun 15 2007, In : Journal of Biological Chemistry. 282, 24, p. 17816-17827 12 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)

Structure and function of tapes japonica lysozyme

Abe, Y. & Ueda, T., Sep 9 2009, In : Seikagaku. 81, 4, p. 314-319 6 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Structure and function of Δ1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa

Shoyama, Y., Tamada, T., Kurihara, K., Takeuchi, A., Taura, F., Arai, S., Blaber, M., Shoyama, Y., Morimoto, S. & Kuroki, R., Oct 12 2012, In : Journal of Molecular Biology. 423, 1, p. 96-105 10 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Structure and mechanism of the primosome protein DnaT-functional structures for homotrimerization, dissociation of ssDNA from the PriB·ssDNA complex, and formation of the DnaT·ssDNA complex

Fujiyama, S., Abe, Y., Tani, J., Urabe, M., Sato, K., Aramaki, T., Katayama, T. & Ueda, T., Dec 2014, In : FEBS Journal. 281, 23, p. 5356-5370 15 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Structure determination of the major component of the starfish ganglioside molecular species LG-2 by tandem mass spectrometry

Higuchi, R., Matsumoto, S., Isobe, R. & Miyamoto, T., Aug 14 1995, In : Tetrahedron. 51, 33, p. 8961-8968 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum

Lacaille-Dubois, M. A., Timité, G., Mitaine-Offer, A. C., Miyamoto, T., Ramezani, M., Rustaiyan, A., Mirjolet, J. F. & Duchamp, O., May 1 2010, In : Magnetic Resonance in Chemistry. 48, 5, p. 370-374 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Structure–function analyses of a stereotypic rheumatoid factor unravel the structural basis for germline-encoded antibody autoreactivity

Shiroishi, M., Ito, Y., Shimokawa, K., Lee, J. M., Kusakabe, T. & Ueda, T., May 4 2018, In : Journal of Biological Chemistry. 293, 18, p. 7008-7016 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Structure of a new neuritogenic-active ganglioside from the sea cucumber Stichopus japonicus

Kaneko, M., Kisa, F., Yamada, K., Miyamoto, T. & Higuchi, R., Jan 1 2003, In : European Journal of Organic Chemistry. 6, p. 1004-1008 5 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Structure of a novel multidrug resistance modulator, irciniasulfonic acid, isolated from a marine sponge, Ircinia sp.

Kawakami, A., Miyamoto, T., Higuchi, R., Uchiumi, T., Kuwano, M. & Van Soest, R. W. M., May 7 2001, In : Tetrahedron Letters. 42, 19, p. 3335-3337 3 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Structure of the human histamine H 1 receptor complex with doxepin

Shimamura, T., Shiroishi, M., Weyand, S., Tsujimoto, H., Winter, G., Katritch, V., Abagyan, R., Cherezov, V., Liu, W., Han, G. W., Kobayashi, T., Stevens, R. C. & Iwata, S., Jul 7 2011, In : Nature. 475, 7354, p. 65-72 8 p.

Research output: Contribution to journalArticle

557 Citations (Scopus)

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

Haga, K., Kruse, A. C., Asada, H., Yurugi-Kobayashi, T., Shiroishi, M., Zhang, C., Weis, W. I., Okada, T., Kobilka, B. K., Haga, T. & Kobayashi, T., Feb 23 2012, In : Nature. 482, 7386, p. 547-551 5 p.

Research output: Contribution to journalArticle

558 Citations (Scopus)

Structure of the Membrane Domain of Human Erythrocyte Anion Exchanger 1 Revealed by Electron Crystallography

Yamaguchi, T., Ikeda, Y., Abe, Y., Kuma, H., Kang, D., Hamasaki, N. & Hirai, T., Mar 19 2010, In : Journal of Molecular Biology. 397, 1, p. 179-189 11 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Structures of four new triterpenoid oligoglycosides: DS-penaustrosides A, B, C, and D from the sea cucumber pentacta australis

Miyamoto, T., Togawa, K., Higuchi, R., Komori, T. & Sasaki, T., Jul 1 1992, In : Journal of Natural Products. 55, 7, p. 940-946 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Structures of sugar chains of a p-nitrophenyl acetate-hydrolyzing esterase from the microsomes of rat liver

Natsuka, S., Himeno, M., Hase, S., Ito, H., Ueda, T., Kato, K. & Ikenaka, T., Jan 1 1988, In : Journal of biochemistry. 103, 6, p. 986-991 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
8 Citations (Scopus)

Studies on lymphangiogenesis inhibitors from Korean and Japanese crude drugs

Jeong, D., Watari, K., Shirouzu, T., Ono, M., Koizumi, K., Saiki, I., Kim, Y. C., Tanaka, C., Higuchi, R. & Miyamoto, T., Jan 1 2013, In : Biological and Pharmaceutical Bulletin. 36, 1, p. 152-157 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
5 Citations (Scopus)
17 Citations (Scopus)

Studies on the constituents of marine opisthobranchia, IV. Two new polyhalogenated monoterpenes from the sea hare Aplysia kurodai

Miyamoto, T., Higuchi, R., Marubayashi, N. & Komori, T., Jan 1 1988, In : Liebigs Annalen der Chemie. 1988, 12, p. 1191-1193 3 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Studies on the αL-iduronidase activity of β-glucuronidase preparations from bovine liver, rat liver, and rat preputial gland

Kosaka, H., Isemura, M., Ono, T., Nishimura, Y. & Kato, K., Jul 1 1980, In : Journal of biochemistry. 88, 1, p. 69-75 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Study of the Physiological Role of 3, 3′, 4, 4′, 5-Pentachlorobiphenyl Inducible 54 KDa Protein in Cytosol of Rat Liver

Ishida, T., Hatsumura, M., Tasaki, K., Fukuda, A., Yoshioka, Y., Ishii, Y. & Oguri, K., Jan 1 1998, In : Japanese Journal of Toxicology and Environmental Health. 44, 1

Research output: Contribution to journalArticle

Sulfated lupane triterpene derivatives and a flavone C-glycoside from Gypsophila repens

Elbandy, M., Miyamoto, T. & Lacaille-Dubois, M. A., May 1 2007, In : Chemical and Pharmaceutical Bulletin. 55, 5, p. 808-811 4 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Suppression of carbonic anhydrase III in rat liver by a dioxin-related toxic compound, coplanar polychlorinated biphenyl, 3,3',4,4',5-pentachlorobiphenyl

Ikeda, M., Ishii, Y., Kato, H., Akazawa, D., Hatsumura, M., Ishida, T., Matsusue, K., Yamada, H. & Oguri, K., Aug 1 2000, In : Archives of Biochemistry and Biophysics. 380, 1, p. 159-164 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Suppression of carbonic anhydrase III mRNA level by an aryl hydrocarbon receptor ligand in primary cultured hepatocytes of rat

Ishii, Y., Akazawa, D., Aoki, Y., Yamada, H. & Oguri, K., Jun 1 2005, In : Biological and Pharmaceutical Bulletin. 28, 6, p. 1087-1090 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Suppression of cytochrome P450 3A4 function by UDP-glucuronosyltransferase 2B7 through a protein-protein interaction: Cooperative roles of the cytosolic carboxyl-terminal domain and the luminal anchoring region

Miyauchi, Y., Nagata, K., Yamazoe, Y., Mackenzie, P. I., Yamada, H. & Ishii, Y., Oct 1 2015, In : Molecular Pharmacology. 88, 4, p. 800-812 13 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Suppression of fetal testicular cytochrome P450 17 by maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: A mechanism involving an initial effect on gonadotropin synthesis in the pituitary

Taketoh, J., Mutoh, J., Takeda, T., Ogishima, T., Takeda, S., Ishii, Y., Ishida, T. & Yamada, H., Mar 13 2007, In : Life Sciences. 80, 14, p. 1259-1267 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Suppression of stress proteins, GRP78, GRP94, calreticulin and calnexin in liver endoplasmic reticulum of rat treated with a highly toxic coplanar PCB

Yoshioka, Y., Ishii, Y., Ishida, T., Yamada, H., Oguri, K. & Motojima, K., Jan 1 2001, In : Fukuoka igaku zasshi = Hukuoka acta medica. 92, 5, p. 201-216 16 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Suppression of stress proteins in endoplasmic reticulum in liver cytosol of rats treated with a highly toxic coplanar PCB

Tasaki, K., Ishii, Y., Ishida, T. & Oguri, K., Sep 3 1999, In : Fukuoka Acta Medica. 90, 5, p. 251-258 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Suppressors of DnaAATP imposed overinitiation in Escherichia coli

Charbon, G., Riber, L., Cohen, M., Skovgaard, O., Fujimitsu, K., Katayama, T. & Løbner-Olesen, A., Feb 1 2011, In : Molecular Microbiology. 79, 4, p. 914-928 15 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Survey of solasodine-type glycoalkaloids by western blotting and ELISA using anti-solamargine monoclonal antibody

Putalun, W., Tanaka, H., Yahara, S., Lhieochaiphan, S. & Shoyama, Y., Jan 2000, In : Biological and Pharmaceutical Bulletin. 23, 1, p. 72-75 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Synthesis and absolute stereochemistry of the acyl moiety of quillajasaponins

Zhu, X., Yu, B., Hui, Y., Higuchi, R., Kusano, T. & Miyamoto, T., Jan 29 2000, In : Tetrahedron Letters. 41, 5, p. 717-719 3 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Synthesis and properties of a mercapto[15]annulenone: A 14π diatropic annulene triply characterised by a fast chemical exchange, tautomerisation, and cis-trans-isomerisation

Ogawa, H., Yoshikawa, M., Tanaka, H., Imoto, T., Miyamoto, I., Kato, H., Taniguchi, Y., Nogami, Y. & Koga, T., Jan 1 1989, In : Journal of the Chemical Society, Chemical Communications. 8, p. 505-507 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Synthesis of 12- O-Mono- and Diglycosyl-oxystearates, a New Class of Agonists for the C-type Lectin Receptor Mincle

Van Huy, L., Tanaka, C., Imai, T., Yamasaki, S. & Miyamoto, T., Oct 1 2019, In : ACS Medicinal Chemistry Letters. 10, 1, p. 44-49 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Synthesis of a hematoside analog containing phytosphingosine and α-hydroxfatty acid

Sugata, T., Kan, Y., Nagaregawa, Y., Miyamoto, T. & Higuchi, R., Jan 1 1997, In : Journal of Carbohydrate Chemistry. 16, 6, p. 917-925 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Synthesis of simple sea cucumber ganglioside analogs

Higuchi, R., Mori, T., Sugata, T., Yamada, K. & Miyamoto, T., Nov 1 1999, In : European Journal of Organic Chemistry. 11, p. 3175-3178 4 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Synthetic studies on the natural multidrug resistance modulator, irciniasulfonic acid B

Emura, C., Higuchi, R. & Miyamoto, T., 2010, In : Chemistry Letters. 39, 9, p. 1002-1003 2 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Tannins and Related Compounds. L.1) Structures of Proanthocyanidin A-l and Related Compounds

Nonaka, G. I., Morimoto, S., Nishioka, I., Kinjo, J. E. & Nohara, T., Jan 1 1987, In : Chemical and Pharmaceutical Bulletin. 35, 1, p. 149-155 7 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Tannins and Related Compounds. LIX.1)Aesculitannins, Novel Proanthocyanidins with Doubly-Bonded Structures from Aesculus hippocastanum L.

Morimoto, S., Nonaka, G. I. & Nishioka, I., Jan 1 1987, In : Chemical and Pharmaceutical Bulletin. 35, 12, p. 4717-4729 13 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
31 Citations (Scopus)