Research Output

Cooperative working of bacterial chromosome replication proteins generated by a reconstituted protein expression system

Fujiwara, K., Katayama, T. & Nomura, S. I. M., Aug 2013, In : Nucleic acids research. 41, 14, p. 7176-7183 8 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2 Citations (Scopus)

Correlation between the differences in the free energy change and conformational energy in the folded state of hen lysozymes with gly-pro and pro-gly sequences introduced to the same site

Motoshima, H., Ueda, T., Hashimoto, Y., Tsutsumi, M. & Imoto, T., Dec 1995, In : Journal of biochemistry. 118, 6, p. 1138-1144 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Costunolide, a sesquiterpene lactone from Saussurea lappa, inhibits the VEGFR KDR/Flk-1 signaling pathway

Jeong, S. J., Itokawa, T., Shibuya, M., Kuwano, M., Ono, M., Higuchi, R. & Miyamoto, T., Dec 10 2002, In : Cancer Letters. 187, 1-2, p. 129-133 5 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Covalent binding of nitroso-sulfonamides to glutathione S-transferase in guinea pigs with delayed type hypersensitivity

Eyanagi, R., Toda, A., Imoto, M., Uchiyama, H., Ishii, Y., Kuroki, H., Kuramoto, Y., Soeda, S. & Shimeno, H., Apr 1 2012, In : International Immunopharmacology. 12, 4, p. 694-700 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Creating a unique environment for selecting reactive enzymes with DNA: 'Sticky' binding of oligocation-grafted polymers to DNA

Tanaka, H., Mori, T., Niidome, T. & Katayama, Y., Feb 1 2012, In : Bioorganic and Medicinal Chemistry. 20, 3, p. 1346-1353 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Crocin and crocetin derivatives inhibit skin tumour promotion in mice

Konoshima, T., Takasaki, M., Tokuda, H., Morimoto, S., Tanaka, H., Kawata, E., Xuan, L. J., Saito, H., Sugiura, M., Molnar, J. & Shoyama, Y., Sep 1 1998, In : Phytotherapy Research. 12, 6, p. 400-404 5 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Crocin prevents the death of PC-12 cells through sphingomyelinase-ceramide signaling by increasing glutathione synthesis

Ochiai, T., Soeda, S., Ohno, S., Tanaka, H., Shoyama, Y. & Shimeno, H., Apr 2004, In : Neurochemistry International. 44, 5, p. 321-330 10 p.

Research output: Contribution to journalArticle

95 Citations (Scopus)

Crocin prevents the death of rat pheochromyctoma (PC-12) cells by its antioxidant effects stronger than those of α-tocopherol

Ochiai, T., Ohno, S., Soeda, S., Tanaka, H., Shoyama, Y. & Shimeno, H., May 13 2004, In : Neuroscience Letters. 362, 1, p. 61-64 4 p.

Research output: Contribution to journalArticle

186 Citations (Scopus)

Crocin promotes non-rapid eye movement sleep in mice

Masaki, M., Aritake, K., Tanaka, H., Shoyama, Y., Huang, Z. L. & Urade, Y., Feb 1 2012, In : Molecular Nutrition and Food Research. 56, 2, p. 304-308 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Crocin suppresses tumor necrosis factor-α-induced cell death of neuronally differentiated PC-12 cells

Soeda, S., Ochiai, T., Paopong, L., Tanaka, H., Shoyama, Y. & Shimeno, H., Nov 2 2001, In : Life Sciences. 69, 24, p. 2887-2898 12 p.

Research output: Contribution to journalArticle

126 Citations (Scopus)

Cross-reactivity of various tetrahydrocannabinol metabolites with a monoclonal antibody against tetrahydrocannabinolic acid

Watanabe, K., Matsuda, M., Tateoka, Y., Kimura, T., Matsunaga, T., Tanaka, H., Shoyama, Y. & Yamamoto, I., Jan 1 2000, In : Journal of Health Science. 46, 4, p. 310-313 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA

Sun, J., Evrin, C., Samel, S. A., Fernández-Cid, A., Riera, A., Kawakami, H., Stillman, B., Speck, C. & Li, H., Aug 1 2013, In : Nature Structural and Molecular Biology. 20, 8, p. 944-951 8 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)
1 Citation (Scopus)

Crystallization and preliminary X-ray diffraction studies of polyketide synthase-1 (PKS-1) from Cannabis sativa

Taguchi, C., Taura, F., Tamada, T., Shoyama, Y., Shoyama, Y., Tanaka, H., Kuroki, R. & Morimoto, S., Mar 13 2008, In : Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 64, 3, p. 217-220 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Crystallization of Human Erythrocyte Band 3, the anion exchanger, at the International Space Station “KIBO”

Hatae, H., Inaka, K., Okamura, R., Furubayashi, N., Kamo, M., Kobayashi, T., Abe, Y., Iwata, S. & Hamasaki, N., Oct 15 2018, In : Analytical Biochemistry. 559, p. 91-93 3 p.

Research output: Contribution to journalArticle

Crystallization of Δ1-tetrahydrocannabinolic acid (THCA) synthase from Cannabis sativa

Shoyama, Y., Takeuchi, A., Taura, F., Tamada, T., Adachi, M., Kuroki, R., Shoyama, Y. & Morimoto, S., Aug 1 2005, In : Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 61, 8, p. 799-801 3 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Crystal structure and calcium-induced conformational changes of diacylglycerol kinase α EF-hand domains

Takahashi, D., Suzuki, K., Sakamoto, T., Iwamoto, T., Murata, T. & Sakane, F., Apr 2019, In : Protein Science. 28, 4, p. 694-706 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Crystal structure-based virtual screening for fragment-like ligands of the human histamine H 1 receptor

De Graaf, C., Kooistra, A. J., Vischer, H. F., Katritch, V., Kuijer, M., Shiroishi, M., Iwata, S., Shimamura, T., Stevens, R. C., De Esch, I. J. P. & Leurs, R., Dec 8 2011, In : Journal of Medicinal Chemistry. 54, 23, p. 8195-8206 12 p.

Research output: Contribution to journalArticle

162 Citations (Scopus)

Crystal structure of a biologically functional form of PriB from Escherichia coli reveals a potential single-stranded DNA-binding site

Shioi, S., Ose, T., Maenaka, K., Shiroishi, M., Abe, Y., Kohda, D., Katayama, T. & Ueda, T., Jan 28 2005, In : Biochemical and Biophysical Research Communications. 326, 4, p. 766-776 11 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
64 Citations (Scopus)
59 Citations (Scopus)

Crystal structure of the anion exchanger domain of human erythrocyte band 3

Arakawa, T., Kobayashi-Yurugi, T., Alguel, Y., Iwanari, H., Hatae, H., Iwata, M., Abe, Y., Hino, T., Ikeda-Suno, C., Kuma, H., Kang, D., Murata, T., Hamakubo, T., Cameron, A. D., Kobayashi, T., Hamasaki, N. & Iwata, S., Nov 6 2015, In : Science. 350, 6261, p. 680-684 5 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

Crystal structure of the complex of the interaction domains of Escherichia coli DnaB helicase and DnaC helicase loader: Structural basis implying a distortion-accumulation mechanism for the DnaB ring opening caused by DnaC binding

Nagata, K., Okada, A., Ohtsuka, J., Ohkuri, T., Akama, Y., Sakiyama, Y., Miyazaki, E., Horita, S., Katayama, T., Ueda, T. & Tanokura, M., Jan 1 2020, In : Journal of biochemistry. 167, 1, p. 1-14 14 p.

Research output: Contribution to journalArticle

Open Access

Crystal structure of the enzyme CapF of Staphyloccus aureus reveals a unique architecture composed of two functional domains

Miyafusa, T., Caaveiro, J. M. M., Tanaka, Y. & Tsumoto, K., 2012, In : Biochemical Journal. 443, p. 671-680 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Crystal structure of the human monocyte-activating receptor, "Group 2" leukocyte Ig-like receptor A5 (LILRA5/LIR9/ILT11)

Shiroishi, M., Kajikawa, M., Kuroki, K., Ose, T., Kohda, D. & Maenaka, K., Jul 14 2006, In : Journal of Biological Chemistry. 281, 28, p. 19536-19544 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Crystal structures of K33 mutant hen lysozymes with enhanced activities

Goto, T., Ohkuri, T., Shioi, S., Abe, Y., Imoto, T. & Ueda, T., Nov 1 2008, In : Journal of biochemistry. 144, 5, p. 619-623 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Crystal structures of the ribonuclease MC1 mutants N71T and N71S in complex with 5′-GMP: Structural basis for alterations in substrate specificity

Numata, T., Suzuki, A., Kakuta, Y., Kimura, K., Yao, M., Tanaka, I., Yoshida, Y., Ueda, T. & Kimura, M., May 13 2003, In : Biochemistry. 42, 18, p. 5270-5278 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

C-terminal cysteine PEGylation of adalimumab fab with an engineered interchain SS bond

Nakamura, H., Anraku, M., Oda-Ueda, N., Ueda, T. & Ohkuri, T., Mar 1 2020, In : Biological and Pharmaceutical Bulletin. 43, 3, p. 418-423 6 p.

Research output: Contribution to journalArticle

Open Access

C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia

Behler-Janbeck, F., Takano, T., Maus, R., Stolper, J., Jonigk, D., Tort Tarrés, M., Fuehner, T., Prasse, A., Welte, T., Timmer, M. S. M., Stocker, B. L., Nakanishi, Y., Miyamoto, T., Yamasaki, S. & Maus, U. A., Dec 6 2016, In : PLoS pathogens. 12, 12, e1006038.

Research output: Contribution to journalArticle

25 Citations (Scopus)

C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection

Toyonaga, K., Torigoe, S., Motomura, Y., Kamichi, T., Hayashi, J. M., Morita, Y. S., Noguchi, N., Chuma, Y., Kiyohara, H., Matsuo, K., Tanaka, H., Nakagawa, Y., Sakuma, T., Ohmuraya, M., Yamamoto, T., Umemura, M., Matsuzaki, G., Yoshikai, Y., Yano, I., Miyamoto, T. & 1 others, Yamasaki, S., Dec 20 2016, In : Immunity. 45, 6, p. 1245-1257 13 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Curcumin anticipates the suppressed body weight gain with 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice

Ishida, T., Taketoh, J., Nakatsune, E., Kan-o, S., Naito, E., Takeda, S., Mutoh, J., Ishii, Y. & Yamada, H., Oct 1 2004, In : Journal of Health Science. 50, 5, p. 474-482 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Cyclic di-GMP acts as a cell cycle oscillator to drive chromosome replication

Lori, C., Ozaki, S., Steiner, S., Böhm, R., Abel, S., Dubey, B. N., Schirmer, T., Hiller, S. & Jenal, U., Jul 9 2015, In : Nature. 523, 7559, p. 236-239 4 p.

Research output: Contribution to journalArticle

90 Citations (Scopus)

Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking

Dubey, B. N., Lori, C., Ozaki, S., Fucile, G., Plaza-Menacho, I., Jenal, U. & Schirmer, T., Sep 2016, In : Science Advances. 2, 9, e1600823.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Cycloartane glycosides from three species of Astragalus (Fabaceae)

Linnek, J., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Paululat, T., Avunduk, S., Alankuş-Çalişkan, Ö. & Lacaille-Dubois, M. A., Feb 1 2011, In : Helvetica Chimica Acta. 94, 2, p. 230-237 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Cycloartane-type glycosides from two species of Astragalus (Fabaceae)

Linnek, J., Mitaine-Offer, A. C., Miyamoto, T., Duchamp, O., Mirjolet, J. F. & Lacaille-Dubois, M. A., 2009, In : Natural product communications. 4, 4, p. 477-478 2 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Cycloartane-type saponins from astragalus tmoleus var. tmoleus

Avunduk, S., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C. & Lacaille-Dubois, M. A., Jan 23 2016, In : Natural product communications. 11, 1, p. 37-38 2 p.

Research output: Contribution to journalArticle

Open Access

Cysteine-to-serine shuffling using a Saccharomyces cerevisiae expression system improves protein secretion: Case of a nonglycosylated mutant of miraculin, a taste-modifying protein

Ito, K., Sugawara, T., Koizumi, A., Nakajima, K. I., Shimizu-Ibuka, A., Shiroishi, M., Asada, H., Yurugi-Kobayashi, T., Shimamura, T., Asakura, T., Misaka, T., Iwata, S., Kobayashi, T. & Abe, K., Jan 1 2011, In : Biotechnology letters. 33, 1, p. 103-107 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
19 Citations (Scopus)

Cytochrome P450-dependent change in UDP-glucuronosyltransferase function and its reverse regulation

Ishii, Y., Miyauchi, Y. & Yamada, H., Jan 1 2014, Fifty Years of Cytochrome P450 Research. Springer Japan, p. 307-326 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cytotoxic acacic acid glycosides from the roots of Albizia coriaria

Noté, O. P., Mitaine-Offer, A. C., Miyamoto, T., Paululat, T., Mirjolet, J. F., Duchamp, O., Pegnyemb, D. E. & Lacaille-Dubois, M. A., Oct 23 2009, In : Journal of Natural Products. 72, 10, p. 1725-1730 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Cytotoxic and ichthyotoxic compounds from marine Opisthobranchia and soft coral

Higuchi, R., Miyamoto, T., Yamada, K. & Komori, T., Jan 1 1998, In : Toxicon. 36, 11, p. 1703-1705 3 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Cytotoxic lavandulyl flavanones from Sophora flavescens

Kang, T. H., Jeong, S. J., Ko, W. G., Kim, N. Y., Lee, B. H., Inagaki, M., Miyamoto, T., Higuchi, R. & Kim, Y. C., May 1 2000, In : Journal of Natural Products. 63, 5, p. 680-681 2 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)

Cytotoxic spirostane-type saponins from the roots of Chlorophytum borivilianum

Acharya, D., Mitaine-Offer, A. C., Kaushik, N., Miyamoto, T., Paululat, T., Mirjolet, J. F., Duchamp, O. & Lacaille-Dubois, M. A., Jan 1 2009, In : Journal of Natural Products. 72, 1, p. 177-181 5 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

De- and repolarization mechanism of flagellar morphogenesis during a bacterial cell cycle

Davis, N. J., Cohen, Y., Sanselicio, S., Fumeaux, C., Ozaki, S., Luciano, J., Guerrero-Ferreira, R. C., Wright, E. R., Jenal, U. & Viollier, P. H., Sep 2013, In : Genes and Development. 27, 18, p. 2049-2062 14 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Decrease in expression of the master operon of flagellin synthesis in a dnaA46 mutant of Escherichia coli

Mizushima, T., Koyanagi, R., Katayama, T., Miki, T. & Sekimizu, K., Jan 1 1997, In : Biological and Pharmaceutical Bulletin. 20, 4, p. 327-331 5 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Decrease in prostaglandin level is a prerequisite for the expression of cannabinoid withdrawal: A quasi abstinence approach

Anggadiredja, K., Yamaguchi, T., Tanaka, H., Shoyama, Y., Watanabe, S. & Yamamoto, T., Dec 20 2005, In : Brain Research. 1066, 1-2, p. 201-205 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Delta(9)-tetrahydrocannabinol enhances an increase of plasma corticosterone levels induced by forced swim-stress

Sano, K., Koushi, E., Irie, K., Higuchi, S., Tsuchihashi, R., Kinjo, J., Egashira, N., Oishi, R., Uchida, N., Nagai, H., Nishimura, R., Tanaka, H., Morimoto, S., Mishima, K., Iwasaki, K. & Fujiwara, M., Dec 1 2009, In : Biological and Pharmaceutical Bulletin. 32, 12, p. 2065-2067 3 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Demethylation of methylmercury and the enhanced production of formaldehyde in mouse liver

Uchikawa, T., Kanno, T., Maruyama, I., Mori, N., Yasutake, A., Ishii, Y. & Yamada, H., Jan 1 2016, In : Journal of Toxicological Sciences. 41, 4, p. 479-487 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Denatured mammalian protein mixtures exhibit unusually high solubility in nucleic acid-free pure water

Futami, J., Fujiyama, H., Kinoshita, R., Nonomura, H., Honjo, T., Tada, H., Matsushita, H., Abe, Y. & Kakimi, K., Nov 18 2014, In : PloS one. 9, 11, e113295.

Research output: Contribution to journalArticle

6 Citations (Scopus)