Research Output

Identification of novel human Cdt1-binding proteins by a proteomics approach: Proteolytic regulation by APC/CCdh1

Sugimoto, N., Kitabayashi, I., Osano, S., Tatsumi, Y., Yugawa, T., Narisawa-Saito, M., Matsukage, A., Kiyono, T. & Fujita, M., Mar 2008, In : Molecular biology of the cell. 19, 3, p. 1007-1021 15 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Identification of lipophilic ligands of Siglec5 and -14 that modulate innate immune responses

Suematsu, R., Miyamoto, T., Saijo, S., Yamasaki, S., Tada, Y., Yoshida, H. & Miyake, Y., Nov 8 2019, In : Journal of Biological Chemistry. 294, 45, p. 16776-16788 13 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Identification of latent procathepsins B and L in microsomal lumen: Characterization of enzymatic activation and proteolytic processing in vitro

Nishimura, Y., Kawabata, T. & Kato, K., Feb 15 1988, In : Archives of Biochemistry and Biophysics. 261, 1, p. 64-71 8 p.

Research output: Contribution to journalArticle

148 Citations (Scopus)

Identification of latent procathepsin H in microsomal lumen: Characterization of proteolytic processing and enzyme activation

Nishimura, Y. & Kato, K., Feb 1 1988, In : Archives of Biochemistry and Biophysics. 260, 2, p. 712-718 7 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Identification of immunoglobulin gene sequences from a small read number of mRNA-seq using hybridomas

Kuniyoshi, Y., Maehara, K., Iwasaki, T., Hayashi, M., Semba, Y., Fujita, M., Sato, Y., Kimura, H., Harada, A. & Ohkawa, Y., Oct 2016, In : PloS one. 11, 10, e0165473.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Identification of distinct ligands for the C-type lectin receptors mincle and dectin-2 in the pathogenic fungus Malassezia

Ishikawa, T., Itoh, F., Yoshida, S., Saijo, S., Matsuzawa, T., Gonoi, T., Saito, T., Okawa, Y., Shibata, N., Miyamoto, T. & Yamasaki, S., Apr 17 2013, In : Cell Host and Microbe. 13, 4, p. 477-488 12 p.

Research output: Contribution to journalArticle

111 Citations (Scopus)

Identification of Cannabis pollens using an allergic patient's immunoglobulin E and purification and characterization of allergens in Cannabis pollens

Tanaka, H., Degawa, M., Kawata, E., Hayashi, J. & Shoyama, Y., Nov 9 1998, In : Forensic Science International. 97, 2-3, p. 139-153 15 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10

Yokoyama, T., Yukuhiro, M., Iwasaki, Y., Tanaka, C., Sankoda, K., Fujiwara, R., Shibuta, A., Higashi, T., Motoyama, K., Arima, H., Yoshida, K., Sugimoto, N., Morimoto, H., Kosako, H., Ohshima, T. & Fujita, M., Dec 1 2019, In : Scientific reports. 9, 1, 16825.

Research output: Contribution to journalArticle

Open Access
36 Citations (Scopus)

Identification and molecular characterization of novel peroxidase with structural protein-like properties

Morimoto, S., Tateishi, N., Inuyama, M., Taura, F., Tanaka, H. & Shoyama, Y., Sep 10 1999, In : Journal of Biological Chemistry. 274, 37, p. 26192-26198 7 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Identification and differentiation of Panax species using ELISA, RAPD and eastern blotting

Tanaka, H., Fukuda, N. & Shoyama, Y., Jan 1 2006, In : Phytochemical Analysis. 17, 1, p. 46-55 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Identification and characterization of major histocompatibility complex class II compartments in cortical thymic epithelial cells

Arudchelvan, Y., Nishimura, Y., Tokuda, N., Sawada, T., Ueyama, Y. & Fukumoto, T., Sep 1 2003, In : Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology. 274, 1, p. 798-806 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Identification and characterization of cannabinoids that induce cell death through mitochondrial permeability transition in cannabis leaf cells

Morimoto, S., Tanaka, Y., Sasaki, K., Tanaka, H., Fukamizu, T., Shoyama, Y., Shoyama, Y. & Taura, F., Jul 13 2007, In : Journal of Biological Chemistry. 282, 28, p. 20739-20751 13 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Ibudilast attenuates doxorubicin-induced cytotoxicity by suppressing formation of TRPC3 channel and NADPH oxidase 2 protein complexes

Nishiyama, K., Numaga-Tomita, T., Fujimoto, Y., Tanaka, T., Toyama, C., Nishimura, A., Yamashita, T., Naoya, M., Satoru, K., Azuma, Y. T., Ibuki, Y., Uchida, K., Ohdo, S. & Nishida, M., Sep 1 2019, In : British Journal of Pharmacology. 176, 18, p. 3723-3738 16 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Hyperactive initiation of chromosomal replication in vivo and in vitro by a mutant initiator protein, DnaAcos, of Escherichia coli

Katayama, T. & Kornberg, A., Apr 29 1994, In : Journal of Biological Chemistry. 269, 17, p. 12698-12703 6 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Hydrogen peroxide induced responses of cat tracheal smooth muscle cells

Bauer, V., Oike, M., Tanaka, H., Inoue, R. & Ito, Y., 1997, In : British Journal of Pharmacology. 121, 5, p. 867-874 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Hyaluronidase inhibitory active 6H-dibenzo[b,d]pyran-6-ones from the feces of Trogopterus xanthipes

Jeong, S. J., Kim, N. Y., Kim, D. H., Kang, T. H., Ahn, N. H., Miyamoto, T., Higuchi, R. & Kim, Y. C., 2000, In : Planta medica. 66, 1, p. 76-77 2 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Human mitochondrial DNA is packaged with TFAM

Alam, T. I., Kanki, T., Muta, T., Ukaji, K., Abe, Y., Nakayama, H., Takio, K., Hamasaki, N. & Kang, D., Mar 15 2003, In : Nucleic acids research. 31, 6, p. 1640-1645 6 p.

Research output: Contribution to journalReview article

226 Citations (Scopus)

Human mincle binds to cholesterol crystals and triggers innate immune responses

Kiyotake, R., Oh-Hora, M., Ishikawa, E., Miyamoto, T., Ishibashi, T. & Yamasaki, S., Oct 16 2015, In : Journal of Biological Chemistry. 290, 42, p. 25322-25332 11 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G

Shiroishi, M., Tsumoto, K., Amano, K., Shirakihara, Y., Colonna, M., Braud, V. M., Allan, D. S. J., Makadzange, A., Rowland-Jones, S., Willcox, B., Jones, E. Y., Van Der Merwe, P. A., Kumagai, I. & Maenaka, K., Jul 22 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 15, p. 8856-8861 6 p.

Research output: Contribution to journalArticle

361 Citations (Scopus)

HM1.24 is internalized from lipid rafts by Clathrin-mediated endocytosis through interaction with α-adaptin

Masuyama, N., Kuronita, T., Tanaka, R., Muto, T., Hirota, Y., Takigawa, A., Fujita, H., Aso, Y., Amano, J. & Tanaka, Y., Jun 5 2009, In : Journal of Biological Chemistry. 284, 23, p. 15927-15941 15 p.

Research output: Contribution to journalArticle

114 Citations (Scopus)

HM1.24/BST-2 is constitutively poly-ubiquitinated at the N-terminal amino acid in the cytoplasmic domain

Fujimoto, K., Nakashima, S., Uchida, S., Amen, R. N. S., Ishii, Y., Hirota, Y. & Tanaka, Y., Sep 2020, In : Biochemistry and Biophysics Reports. 23, 100784.

Research output: Contribution to journalArticle

Open Access

HIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomes

Iwabu, Y., Fujita, H., Kinomoto, M., Kaneko, K., Ishizaka, Y., Tanaka, Y., Sata, T. & Tokunaga, K., Dec 11 2009, In : Journal of Biological Chemistry. 284, 50, p. 35060-35072 13 p.

Research output: Contribution to journalArticle

171 Citations (Scopus)

Histone acetyltransferase Hbo1: Catalytic activity, cellular abundance, and links to primary cancers

Iizuka, M., Takahashi, Y., Mizzen, C. A., Cook, R. G., Fujita, M., Allis, C. D., Frierson, H. F., Fukusato, T. & Smith, M. M., May 1 2009, In : Gene. 436, 1-2, p. 108-114 7 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Histochemical investigation of β-glucuronidase in culture cells and regenerated plants of Scutellaria baicalensis Georgi

Matsuda, T., Hatano, K., Harioka, T., Taura, F., Tanaka, H., Tateishi, N., Shan, S., Morimoto, S. & Shoyama, Y., Mar 2000, In : Plant Cell Reports. 19, 4, p. 390-394 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Histidinylated poly-L-lysine-based vectors for cancer-specific gene expression via enhancing the endosomal escape

Zhao, G. X., Tanaka, H., Kim, C. W., Li, K., Funamoto, D., Nobori, T., Nakamura, Y., Niidome, T., Kishimura, A., Mori, T. & Katayama, Y., Mar 24 2014, In : Journal of Biomaterials Science, Polymer Edition. 25, 5, p. 519-534 16 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Histidine-834 of Human Erythrocyte Band 3 Has an Essential Role in the Conformational Changes That Occur during the Band 3-Mediated Anion Exchange

Jin, X. R., Abe, Y., Li, C. Y. & Hamasaki, N., Nov 11 2003, In : Biochemistry. 42, 44, p. 12927-12932 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

High-throughput determination of free d-aspartic acid in mammals by enzyme immunoassay using specific monoclonal antibody

Ohgusu, T., Hamase, K., Tanaka, H., Shoyama, Y. & Zaitsu, K., Oct 1 2006, In : Analytical Biochemistry. 357, 1, p. 15-20 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

High performance enzyme-linked immunosorbent assay for determination of miroestrol, a potent phytoestrogen from Pueraria candollei

Yusakul, G., Udomsin, O., Juengwatanatrakul, T., Tanaka, H., Chaichantipyuth, C. & Putalun, W., Jun 27 2013, In : Analytica Chimica Acta. 785, p. 104-110 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Highly sensitive regenerable immunosensor for label-free detection of 2,4-dichlorophenoxyacetic acid at ppb levels by using surface plasmon resonance imaging

Gobi, K. V., Tanaka, H., Shoyama, Y. & Miura, N., Nov 11 2005, In : Sensors and Actuators, B: Chemical. 111-112, SUPPL., p. 562-571 10 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Highly selective and sensitive determination of deoxymiroestrol using a polyclonal antibody-based enzyme-linked immunosorbent assay

Yusakul, G., Udomsin, O., Juengwatanatrakul, T., Tanaka, H., Chaichantipyuth, C. & Putalun, W., Jan 1 2013, In : Talanta. 114, p. 73-78 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Highly organized DnaA-oriC complexes recruit the single-stranded DNA for replication initiation

Ozaki, S. & Katayama, T., Feb 1 2012, In : Nucleic acids research. 40, 4, p. 1648-1665 18 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Highly controlled carbodiimide reaction for the modification of lysozyme. Modification of leu129 or asp119

Ueda, T., Yamada, H. & Imoto, T., Jun 1 1987, In : Protein Engineering, Design and Selection. 1, 3, p. 189-193 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

High-level expression of uniformly 15N-labeled hen lysozyme in Pichia pastoris and identification of the site in hen lysozyme where phosphate ion binds using NMR measurements

Mine, S., Ueda, T., Hashimoto, Y., Tanaka, Y. & Imoto, T., Apr 2 1999, In : FEBS Letters. 448, 1, p. 33-37 5 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Heterooligomer of type 1 and type 2 inositol 1, 4, 5-trisphosphate receptor expressed in rat liver membrane fraction exists as tetrameric complex

Onoue, H., Tanaka, H., Tanaka, K., Doira, N. & Ito, Y., Jan 27 2000, In : Biochemical and Biophysical Research Communications. 267, 3, p. 928-933 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT

Miyauchi, Y., Kurita, A., Yamashita, R., Takamatsu, T., Ikushiro, S., Mackenzie, P. I., Tanaka, Y. & Ishii, Y., Apr 30 2020, In : Biochemical and Biophysical Research Communications. 525, 2, p. 348-353 6 p.

Research output: Contribution to journalArticle

Heterogeneous packing in the folding/unfolding intermediate state of bitter gourd trypsin inhibitor

Takahashi, D., Matsumoto, S., Nishimoto, E., Otosu, T. & Yamashita, S., 2008, In : Bioscience, Biotechnology and Biochemistry. 72, 6, p. 1498-1505 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Heterocomplex formation by Arp4 and β-actin is involved in the integrity of the Brg1 chromatin remodeling complex

Nishimoto, N., Watanabe, M., Watanabe, S., Sugimoto, N., Yugawa, T., Ikura, T., Koiwai, O., Kiyono, T. & Fujita, M., Aug 15 2012, In : Journal of Cell Science. 125, 16, p. 3870-3882 13 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Helicase and its interacting factors: Regulation mechanism, characterization, structure, and application for drug design

Huang, C. Y., Abe, Y., Ding, H. & Chung, I. F., 2015, In : BioMed Research International. 2015, 909047.

Research output: Contribution to journalEditorial

Helical image reconstruction of the outward-open human erythrocyte band 3 membrane domain in tubular crystals

Yamaguchi, T., Fujii, T., Abe, Y., Hirai, T., Kang, D., Namba, K., Hamasaki, N. & Mitsuoka, K., Mar 2010, In : Journal of structural biology. 169, 3, p. 406-412 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Hederagenin glycosides from the fruits of Blighia unijugata

Petit, B., Mitaine-Offer, A. C., Delaude, C., Miyamoto, T., Tanaka, C. & Lacaille-Dubois, M. A., Jun 1 2019, In : Phytochemistry. 162, p. 260-269 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Hda monomerization by ADP binding promotes replicase clamp-mediated DnaA-ATP hydrolysis

Su'etsugu, M., Nakamura, K., Keyamura, K., Kudo, Y. & Katayama, T., Dec 26 2008, In : Journal of Biological Chemistry. 283, 52, p. 36118-36131 14 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Hda, a novel DnaA-related protein, regulates the replication cycle in Escherichia coli

Kato, J. I. & Katayama, T., Aug 1 2001, In : EMBO Journal. 20, 15, p. 4253-4262 10 p.

Research output: Contribution to journalArticle

199 Citations (Scopus)

Guest-induced conformational change of β-cyclodextrin capped with an environmentally sensitive chromophore

Fujita, K., Ueda, T., Imoto, T., Tabushi, I., Toh, N. & Koga, T., Mar 1982, In : Bioorganic Chemistry. 11, 1, p. 72-84 13 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Guest-Induced Conformational Change of 6-Monosubstituted Cyclodextrin

Fujita, K., Ueda, T., Matsunaga, A. & Imoto, T., Jan 1 1983, In : NIPPON KAGAKU KAISHI. 1983, 2, p. 207-213 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, K. I., Yoshida, K., Sugimoto, N. & Fujita, M., Aug 1 2018, In : Journal of cell science. 131, 15

Research output: Contribution to journalArticle

5 Citations (Scopus)

GRWD1 negatively regulates p53 via the RPL11–MDM2 pathway and promotes tumorigenesis

Kayama, K., Watanabe, S., Takafuji, T., Tsuji, T., Hironaka, K., Matsumoto, M., Nakayama, K. I., Enari, M., Kohno, T., Shiraishi, K., Kiyono, T., Yoshida, K., Sugimoto, N. & Fujita, M., Jan 1 2017, In : EMBO Reports. 18, 1, p. 123-137 15 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

GRWD1 directly interacts with p53 and negatively regulates p53 transcriptional activity

Fujiyama, H., Tsuji, T., Hironaka, K., Yoshida, K., Sugimoto, N. & Fujita, M., Jan 1 2020, In : Journal of biochemistry. 167, 1, p. 15-24 10 p.

Research output: Contribution to journalArticle

GRWD1, a new player among oncogenesis-related ribosomal/nucleolar proteins

Takafuji, T., Kayama, K., Sugimoto, N. & Fujita, M., Aug 3 2017, In : Cell Cycle. 16, 15, p. 1397-1403 7 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Green Pharma: A new strategy for drug discovery in academia by targeting glial cells and ATP receptors

Yamashita, T., Makoto, T., Saitoh, H. & Inoue, K., Jan 1 2018, In : Yakugaku Zasshi. 138, 8, p. 1027-1031 5 p.

Research output: Contribution to journalReview article