Research Output 1976 2019

Article
17 Citations (Scopus)

(-)-Axinyssene: A novel cytotoxic diterpene from a Japanese marine sponge Axinyssa sp

Kodama, K., Higuchi, R., Miyamoto, T. & Van Soest, R. W. M., Jan 23 2003, In : Organic Letters. 5, 2, p. 169-171 3 p.

Research output: Contribution to journalArticle

leukemias
Diterpenes
Military Personnel
Porifera
methylene
5 Citations (Scopus)

[The effect of maternal exposure to dioxin on fetal steroidogenesis in the steroidogenic organs].

Takeda, T., Taura, J., Fujii, M., Koga, T., Ishii, Y. & Yamada, H., Apr 2011, In : Fukuoka Acta Medica. 102, 4, p. 159-166 8 p.

Research output: Contribution to journalArticle

Maternal Exposure
Dioxins
Steroid 17-alpha-Hydroxylase
Fetus
Adrenal Glands
3 Citations (Scopus)

[The gender-specific effect of maternal exposure to dioxin on fetal steroidogenesis in the adrenal gland].

Takeda, T., Hattori, Y., Fujii, M., Taura, J., Ishi, Y. & Yamada, H., Jan 1 2013, In : Unknown Journal. 104, 4, p. 143-151 9 p.

Research output: Contribution to journalArticle

Maternal Exposure
Dioxins
Adrenal Glands
Poisons
Fetus
12 Citations (Scopus)

1,3-Dimethylisoguaninium, an antiangiogenic purine analog from the sponge Amphimedon paraviridis

Jeong, S. J., Inagaki, M., Higuchi, R., Miyamoto, T., Ono, M., Kuwano, M. & Van Soest, R. W. M., Jun 2003, In : Chemical and Pharmaceutical Bulletin. 51, 6, p. 731-733 3 p.

Research output: Contribution to journalArticle

Endothelial cells
Porifera
Aorta
Endothelial Cells
Fibroblast Growth Factor 2

181 IL-13の遺伝的多型と気管支喘息との相関

有馬和彦, 白川太郎, Klaus, A. D., 阿部義人, 山下哲次, 榎本雅夫, 嶽良博, 佐々木聖, 赤岩美奈, 于彬, 濱崎直孝, Julian, M. H. & 出原賢治, 2000, In : Japanese Journal of Allergology. 49, 9, p. 938

Research output: Contribution to journalArticle

3 Citations (Scopus)

1H-NMR study of the intramolecular interaction of a substrate analogue covalently attached to aspartic acid-101 in lysozyme

Ueda, T., Isakari, Y., Aoki, H., Yasukochi, T., Masutomo, S. I., Kawano, K., Terada, Y., Yamada, H. & Imoto, T., Jan 1 1991, In : Journal of Biochemistry. 109, 5, p. 690-698 9 p.

Research output: Contribution to journalArticle

Muramidase
Aspartic Acid
Nuclear magnetic resonance
Catalytic Domain
Substrates
4 Citations (Scopus)

2,3,4,7,8-Pentachlorodibenzofuran is far less potent than 2,3,7,8-tetrachlorodibenzo-p-dioxin in disrupting the pituitary-gonad axis of the rat fetus

Taura, J., Takeda, T., Fujii, M., Hattori, Y., Ishii, Y., Kuroki, H., Tsukimori, K., Uchi, H., Furue, M. & Yamada, H., Nov 5 2014, In : Toxicology and Applied Pharmacology. 281, 1, p. 48-57 10 p.

Research output: Contribution to journalArticle

Gonads
Rats
Fetus
Fetal Development
Dioxins
24 Citations (Scopus)

2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced change in intestinal function and pathology: Evidence for the involvement of arylhydrocarbon receptor-mediated alteration of glucose transportation

Ishida, T., Kan-O, S., Mutoh, J., Takeda, S., Ishii, Y., Hashiguchi, I., Akamine, A. & Yamada, H., May 15 2005, In : Toxicology and Applied Pharmacology. 205, 1, p. 89-97 9 p.

Research output: Contribution to journalArticle

Pathology
Sodium-Glucose Transporter 1
Symporters
Glucose
Inbred C57BL Mouse
6 Citations (Scopus)

2,3,7,8-Tetrachlorodibenzo-p-dioxin potentially attenuates the gene expression of pituitary gonadotropin β-subunits in a fetal age-specific fashion: A comparative study using cultured pituitaries

Takeda, T., Yamamoto, M., Himeno, M., Takechi, S., Yamaguchi, T., Ishida, T., Ishii, Y. & Yamada, H., Apr 1 2011, In : Journal of Toxicological Sciences. 36, 2, p. 221-229 9 p.

Research output: Contribution to journalArticle

Pituitary Gonadotropins
Gonadotropins
Gene expression
Gestational Age
Gene Expression
19 Citations (Scopus)

3-Methyladenine specifically inhibits retrograde transport of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor from the early endosome to the TGN

Hirosako, K., Imasato, H., Hirota, Y., Kuronita, T., Masuyama, N., Nishioka, M., Umeda, A., Fujita, H., Himeno, M. & Tanaka, Y., Apr 9 2004, In : Biochemical and Biophysical Research Communications. 316, 3, p. 845-852 8 p.

Research output: Contribution to journalArticle

IGF Type 2 Receptor
trans-Golgi Network
Endosomes
Cations
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
24 Citations (Scopus)

3-Prenyl luteolin, a new prenylated flavone with melanin biosynthesis inhibitory activity from wood of Artocarpus heterophyllus

Arung, E. T., Shimizu, K., Tanaka, H. & Kondo, R., Sep 1 2010, In : Fitoterapia. 81, 6, p. 640-643 4 p.

Research output: Contribution to journalArticle

flavone
Artocarpus
Monophenol Monooxygenase
Melanins
Bleaching Agents

3SD04 ヒト赤血球膜タンパク質Band3の機能と構造(構造から見た膜輸送)

Translated title of the contribution: 3SD04 Functon and Structure of human erythrocyte membrane protein Band 3阿部義人 & 濱崎直孝, 2004, In : 生物物理. 44, 0, p. S24

Research output: Contribution to journalArticle

3 Citations (Scopus)

5′-Nucleotidase in Rat Liver Lysosomal Membranes is anchored via Glycosyl-Phosphatidylinositol

Tanaka, Y., Himeno, M., Taguchi, R., Ikezawa, H. & Kato, K., Jan 1 1989, In : Cell structure and function. 14, 5, p. 597-603 7 p.

Research output: Contribution to journalArticle

Glycosylphosphatidylinositols
5'-Nucleotidase
Membranes
Liver
Phosphoinositide Phospholipase C
34 Citations (Scopus)

70-kDa peroxisomal membrane protein related protein (P70R/ABCD4) localizes to endoplasmic reticulum not peroxisomes, and NH2-terminal hydrophobic property determines the subcellular localization of ABC subfamily D proteins

Kashiwayama, Y., Seki, M., Yasui, A., Murasaki, Y., Morita, M., Yamashita, Y., Sakaguchi, M., Tanaka, Y. & Imanaka, T., Jan 15 2009, In : Experimental Cell Research. 315, 2, p. 190-205 16 p.

Research output: Contribution to journalArticle

Peroxisomes
Endoplasmic Reticulum
Membrane Proteins
Adenosine Triphosphate
Proteins

Abnormalities of the serotonergic system in diacylglycerol kinase δ-deficient mouse brain

Lu, Q., Komenoi, S., Usuki, T., Takahashi, D. & Sakane, F., Mar 18 2018, In : Biochemical and Biophysical Research Communications. 497, 4, p. 1031-1037 7 p.

Research output: Contribution to journalArticle

Diacylglycerol Kinase
Brain
Obsessive-Compulsive Disorder
Knockout Mice
Serotonin
603 Citations (Scopus)

Accumulation of autophagic vacuoles and cardiomyopathy LAMP-2-deficient mice

Tanaka, Y., Guhde, G., Suter, A., Eskelinen, E. L., Hartmann, D., Lüllmann-Rauch, R., Janssen, P. M. L., Blanz, J., Von Figura, K. & Saftig, P., Aug 24 2000, In : Nature. 406, 6798, p. 902-906 5 p.

Research output: Contribution to journalArticle

Lysosome-Associated Membrane Glycoproteins
Vacuoles
Cardiomyopathies
Protein Deficiency
Glycogen Storage Disease Type IIb
15 Citations (Scopus)

A chimera of green fluorescent protein with single chain variable fragment antibody against ginsenosides for fluorescence-linked immunosorbent assay

Sakamoto, S., Tanizaki, Y., Pongkitwitoon, B., Tanaka, H. & Morimoto, S., May 1 2011, In : Protein Expression and Purification. 77, 1, p. 124-130 7 p.

Research output: Contribution to journalArticle

Ginsenosides
Single-Chain Antibodies
Immunosorbents
Green Fluorescent Proteins
Fluorescence
85 Citations (Scopus)

A common mechanism for the ATP-DnaA-dependent formation of open complexes at the replication origin

Ozaki, S., Kawakami, H., Nakamura, K., Fujikawa, N., Kagawa, W., Park, S. Y., Yokoyama, S., Kurumizaka, H. & Katayama, T., Mar 28 2008, In : Journal of Biological Chemistry. 283, 13, p. 8351-8362 12 p.

Research output: Contribution to journalArticle

Replication Origin
Adenosine Triphosphate
Adenosine Diphosphate
Thermotoga maritima
Eubacterium
16 Citations (Scopus)

A coplanar PCB induces a selenium binding protein as a major cytosolic protein in rat liver

Ishii, Y., Hatsumura, M., Ishida, T., Ariyoshi, N. & Oguri, K., Jan 1 1996, In : Chemosphere. 32, 3, p. 509-515 7 p.

Research output: Contribution to journalArticle

Selenium-Binding Proteins
Polychlorinated Biphenyls
Selenium
Polychlorinated biphenyls
selenium
9 Citations (Scopus)

A critical role of MYC for transformation of human cells by HPV16 E6E7 and oncogenic HRAS

Narisawa-Saito, M., Inagawa, Y., Yoshimatsu, Y., Haga, K., Tanaka, K., Egawa, N., Ohno, S. I., Ichikawa, H., Yugawa, T., Fujita, M. & Kiyono, T., Apr 16 2012, In : Carcinogenesis. 33, 4, p. 910-917 8 p.

Research output: Contribution to journalArticle

Keratinocytes
Neoplastic Cell Transformation
Sirolimus
Neoplasms
Foreskin
2 Citations (Scopus)

Activation of a refolded, berberine-specific, single-chain Fv fragment by addition of free berberine

Kim, J. S., Masaki, T., Sirikantaramas, S., Shoyama, Y. & Tanaka, H., Jul 1 2006, In : Biotechnology letters. 28, 13, p. 999-1006 8 p.

Research output: Contribution to journalArticle

Immunoglobulin Variable Region
Berberine
Single-Chain Antibodies
Assays
Enzymes
6 Citations (Scopus)

Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity: A comparative study in humans and rodents including chimeric mice carrying human liver

Nurrochmad, A., Ishii, Y., Nakanoh, H., Inoue, T., Horie, T., Sugihara, K., Ohta, S., Taketomi, A., Maehara, Y. & Yamada, H., Jan 1 2010, In : Drug metabolism and pharmacokinetics. 25, 3, p. 262-273 12 p.

Research output: Contribution to journalArticle

Microsomes
Morphine
Rodentia
Uridine Diphosphate Glucuronic Acid
Liver
16 Citations (Scopus)

Acylated preatroxigenin glycosides from Atroxima congolana

Elbandy, M., Miyamoto, T., Delaude, C. & Lacaille-Dubois, M. A., Sep 1 2003, In : Journal of Natural Products. 66, 9, p. 1154-1158 5 p.

Research output: Contribution to journalArticle

Saponins
Glycosides
Isomers
glycosides
Spectroscopic analysis
5 Citations (Scopus)

Acylated triterpene saponins from Atroxima liberica STAPF

Tabopda, T. K., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Mirjolet, J. F., Duchamp, O., Ngadjui, B. T. & Lacaille-Dubois, M. A., Nov 1 2011, In : Helvetica Chimica Acta. 94, 11, p. 2066-2076 11 p.

Research output: Contribution to journalArticle

Triterpenes
Saponins
Isomers
Esters
isomers
37 Citations (Scopus)

Acylated triterpene saponins from the roots of Securidaca longepedunculata

Mitaine-Offer, A. C., Pénez, N., Miyamoto, T., Delaude, C., Mirjolet, J. F., Duchamp, O. & Lacaille-Dubois, M. A., Jan 1 2010, In : Phytochemistry. 71, 1, p. 90-94 5 p.

Research output: Contribution to journalArticle

Securidaca
Triterpenes
triterpenoid saponins
Saponins
Esters
3 Citations (Scopus)

Adhesive Dimerization of Human P-Cadherin Catalyzed by a Chaperone-like Mechanism

Kudo, S., Caaveiro, J. M. M. & Tsumoto, K., Sep 6 2016, In : Structure. 24, 9, p. 1523-1536 14 p.

Research output: Contribution to journalArticle

Dimerization
Cadherins
Adhesives
Motion Pictures
Thermodynamics
1 Citation (Scopus)

A dihydrochalcone derivative and further steroidal saponins from Sansevieria trifasciata Prain

Tchegnitegni, B. T., Teponno, R. B., Jenett-Siems, K., Melzig, M. F., Miyamoto, T. & Tapondjou, L. A., Oct 26 2017, In : Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 72, 11-12, p. 477-482 6 p.

Research output: Contribution to journalArticle

Sansevieria
Aconitic Acid
Saponins
Derivatives
Spectroscopic analysis
26 Citations (Scopus)

Advanced method for high-throughput expression of mutated eukaryotic membrane proteins in Saccharomyces cerevisiae

Ito, K., Sugawara, T., Shiroishi, M., Tokuda, N., Kurokawa, A., Misaka, T., Makyio, H., Yurugi-Kobayashi, T., Shimamura, T., Nomura, N., Murata, T., Abe, K., Iwata, S. & Kobayashi, T., Jul 11 2008, In : Biochemical and Biophysical Research Communications. 371, 4, p. 841-845 5 p.

Research output: Contribution to journalArticle

Yeast
Saccharomyces cerevisiae
Membrane Proteins
Yeasts
Homologous Recombination
34 Citations (Scopus)

Affinity improvement of a therapeutic antibody by structure-based computational design: generation of electrostatic interactions in the transition state stabilizes the antibody-antigen complex

Kiyoshi, M., Caaveiro, J. M. M., Miura, E., Nagatoishi, S., Nakakido, M., Soga, S., Shirai, H., Kawabata, S. & Tsumoto, K., 2014, In : PLoS One. 9, 1, 9 p., e87099.

Research output: Contribution to journalArticle

Open Access
antigen-antibody complex
electrostatic interactions
Coulomb interactions
Antigen-Antibody Complex
Static Electricity
22 Citations (Scopus)
Cathepsin H
Epithelial Attachment
Cathepsin B
Cysteine Proteases
Horseradish Peroxidase
8 Citations (Scopus)

A fluorescent single domain antibody against plumbagin expressed in silkworm larvae for fluorescence-linked immunosorbent assay (FLISA)

Sakamoto, S., Pongkitwitoon, B., Sasaki-Tabata, K., Putalun, W., Maenaka, K., Tanaka, H. & Morimoto, S., May 21 2011, In : Analyst. 136, 10, p. 2056-2063 8 p.

Research output: Contribution to journalArticle

Single-Domain Antibodies
Immunosorbents
Bombyx
chimera
Antibodies
25 Citations (Scopus)

Age-related disruption of autophagy in dermal fibroblasts modulates extracellular matrix components

Tashiro, K., Shishido, M., Fujimoto, K., Hirota, Y., Yo, K., Gomi, T. & Tanaka, Y., Jan 3 2014, In : Biochemical and Biophysical Research Communications. 443, 1, p. 167-172 6 p.

Research output: Contribution to journalArticle

Autophagy
Fibroblasts
Extracellular Matrix
Skin
Aging of materials
29 Citations (Scopus)

Aggregates with lysozyme and ovalbumin show features of amyloid-like fibrils

Sugimoto, Y., Kamada, Y., Tokunaga, Y., Shinohara, H., Matsumoto, M., Kusakabe, T., Ohkuri, T. & Ueda, T., Dec 2011, In : Biochemistry and Cell Biology. 89, 6, p. 533-544 12 p.

Research output: Contribution to journalArticle

Ovalbumin
Muramidase
Amyloid
Egg White
Peptides
37 Citations (Scopus)

Aggregation and chemical reaction in hen lysozyme caused by heating at pH 6 are depressed by osmolytes, sucrose and trehalose

Ueda, T., Nagata, M. & Imoto, T., Jan 1 2001, In : Journal of Biochemistry. 130, 4, p. 491-496 6 p.

Research output: Contribution to journalArticle

Trehalose
Muramidase
Heating
Sucrose
Chemical reactions
26 Citations (Scopus)
Biphenyl Compounds
Poisons
Polychlorinated Biphenyls
Unsaturated Fatty Acids
Arachidonic Acid
26 Citations (Scopus)

A highly toxic PCB produces unusual changes in the fatty acid composition of rat liver

Matsusue, K., Ishii, Y., Ariyoshi, N. & Oguri, K., Apr 28 1997, In : Toxicology Letters. 91, 2, p. 99-104 6 p.

Research output: Contribution to journalArticle

Glycerophospholipids
3,4,5,3',4'-pentachlorobiphenyl
Poisons
Polychlorinated Biphenyls
Lipid Metabolism
4 Citations (Scopus)

A lateral flow colloidal gold-based immunoassay for rapid detection of miroestrol in samples of White Kwao Krua, a phytoestrogen-rich plant

Kitisripanya, T., Inyai, C., Komaikul, J., Krittanai, S., Juengwatanatrakul, T., Sakamoto, S., Tanaka, H., Morimoto, S. & Putalun, W., Oct 1 2017, In : Journal of Natural Medicines. 71, 4, p. 659-664 6 p.

Research output: Contribution to journalArticle

Gold Colloid
Phytoestrogens
Immunoassay
Assays
Immunosorbents

Alginate immobilization of Morus alba L. cell suspension cultures improved the accumulation and secretion of stilbenoids

Inyai, C., Boonsnongcheep, P., Komaikul, J., Sritularak, B., Tanaka, H. & Putalun, W., Jan 30 2019, In : Bioprocess and Biosystems Engineering. 42, 1, p. 131-141 11 p.

Research output: Contribution to journalArticle

Morus
Alginate
Resveratrol
Immobilized Cells
Immobilization
2 Citations (Scopus)

Alleviation of fatty liver in a rat model by enhancing N 1 -methylnicotinamide bioavailability through aldehyde oxidase inhibition

Takeuchi, K., Yokouchi, C., Goto, H., Umehara, K., Yamada, H. & Ishii, Y., Dec 9 2018, In : Biochemical and Biophysical Research Communications. 507, 1-4, p. 203-210 8 p.

Research output: Contribution to journalArticle

Open Access
Aldehyde Oxidase
Fatty Liver
Liver
Biological Availability
Rats

Alpha-mangostin ameliorates bleomycin-induced pulmonary fibrosis in mice partly through activating adenosine 5′-monophosphate-activated protein kinase

Li, R. S., Xu, G. H., Cao, J., Liu, B., Xie, H. F., Ishii, Y. & Zhang, C. F., Jan 1 2019, In : Frontiers in Pharmacology. 10, 1305.

Research output: Contribution to journalArticle

Open Access
Pulmonary Fibrosis
Bleomycin
Adenosine Monophosphate
Protein Kinases
Lung
15 Citations (Scopus)

Alteration of the function of the UDP-glucuronosyltransferase 1A subfamily by cytochrome P450 3A4: Different susceptibility for UGT isoforms and UGT1A1/7 variantss

Ishii, Y., Koba, H., Kinoshita, K., Oizaki, T., Iwamoto, Y., Takeda, S., Miyauchi, Y., Nishimura, Y., Egoshi, N., Taura, F., Morimoto, S., Ikushiro, SI., Nagata, K., Yamazoe, Y., MacKenzie, P. I. & Yamada, H., Feb 1 2014, In : Drug Metabolism and Disposition. 42, 2, p. 229-238 10 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Glucuronosyltransferase
Protein Isoforms
irinotecan
Acids

A metal binding in the polypeptide chain improves the folding efficiency of a denatured and reduced protein

Ohkuri, T., Ueda, T., Yoshida, Y., Abe, Y., Hamasaki, N. & Imoto, T., Jul 5 2002, In : Biopolymers. 64, 2, p. 106-114 9 p.

Research output: Contribution to journalArticle

Polypeptides
Muramidase
Enzymes
Metals
Proteins
26 Citations (Scopus)
endoproteinase Asp-N
Asparagine
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Muramidase
Viperidae

A method to induce hen egg lysozyme-specific humoral immune tolerance in mice by pre-exposition with the protein's oligomers

Ohkuri, T., Yuge, N., Sato, K. & Ueda, T., Dec 1 2019, In : Biochemistry and Biophysics Reports. 20, 100679.

Research output: Contribution to journalArticle

Open Access
Immune Tolerance
Oligomers
Antibodies
Anti-Idiotypic Antibodies
Proteins
2 Citations (Scopus)

A Monoclonal Antibody-Based Enzyme-Linked Immunosorbent Assay for Determination of Homoharringtonine

Pongkitwitoon, B., Sakamoto, S., Nagamitsu, R., Putalun, W., Tanaka, H. & Morimoto, S., Feb 28 2018, In : Planta medica. 84, 14, p. 1038-1044 7 p.

Research output: Contribution to journalArticle

Immunosorbents
Assays
Enzyme-Linked Immunosorbent Assay
Monoclonal Antibodies
Enzymes
1 Citation (Scopus)

A monoclonal antibody-based immunoassay for the determination of oxyresveratrol from Artocarpus lacucha Buch.-Ham

Kitisripanya, T., Inyai, C., Krittanai, S., Likhitwitayawuid, K., Sritularak, B., Ploypradith, P., Tanaka, H., Morimoto, S. & Putalun, W., Jul 1 2017, In : Journal of Natural Medicines. 71, 3, p. 523-530 8 p.

Research output: Contribution to journalArticle

Artocarpus
Immunoassay
Monoclonal Antibodies
Assays
Immunosorbents
6 Citations (Scopus)

Amounts of proteins altered by mutations in the dnaA gene of Escherichia coli

Ohba, A., Mizushima, T., Katayama, T. & Sekimizu, K., Mar 10 1997, In : FEBS Letters. 404, 2-3, p. 125-128 4 p.

Research output: Contribution to journalArticle

Escherichia coli
Genes
Mutation
holo-(acyl-carrier-protein) synthase
Fatty Acid Transport Proteins
12 Citations (Scopus)

Amphimelibiosides A-F, six new ceramide dihexosides isolated from a Japanese marine sponge Amphimedon sp.

Emura, C., Higuchi, R., Miyamoto, T. & Van Soest, R. W. M., Apr 15 2005, In : Journal of Organic Chemistry. 70, 8, p. 3031-3038 8 p.

Research output: Contribution to journalArticle

Nuclear magnetic resonance
Degradation
ceramide dihexoside
1-octadecene
45 Citations (Scopus)

A mutation study of catalytic residue Asp 52 in hen egg lysozyme

Hashimoto, Y., Yamada, K., Motoshima, H., Omura, T., Yamada, H., Yasukochi, T., Miki, T., Ueda, T. & Imoto, T., Jan 1 1996, In : Journal of Biochemistry. 119, 1, p. 145-150 6 p.

Research output: Contribution to journalArticle

Muramidase
Yeast
Mutation
Extremities
Yeasts
16 Citations (Scopus)

Amyloid formation in denatured single-mutant lysozymes where residual structures are modulated

Mishima, T., Ohkuri, T., Monji, A., Imoto, T. & Ueda, T., Oct 9 2006, In : Protein Science. 15, 10, p. 2448-2452 5 p.

Research output: Contribution to journalArticle

Muramidase
Amyloid
Ports and harbors
Spectrum Analysis
Fluorescence