Research Output

LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice

Gamp, A. C., Tanaka, Y., Lüllmann-Rauch, R., Wittke, D., D'Hooge, R., De Deyn, P. P., Moser, T., Maier, H., Hartmann, D., Reiss, K., Illert, A. L., von Figura, K. & Saftig, P., Mar 15 2003, In : Human Molecular Genetics. 12, 6, p. 631-646 16 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection

Imai, T., Matsumura, T., Mayer-Lambertz, S., Wells, C. A., Ishikawa, E., Butcher, S. K., Barnett, T. C., Walker, M. J., Imamura, A., Ishida, H., Ikebe, T., Miyamoto, T., Ato, M., Ohga, S., Lepenies, B., Van Sorge, N. M. & Yamasaki, S., Nov 6 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 45, p. E10662-E10671

Research output: Contribution to journalArticle

11 Citations (Scopus)

Localization of cathepsin L in rat kidney revealed by immunoenzyme and immunogold techniques

Yokota, S., Nishimura, Y. & Kato, K., Jul 1 1988, In : Histochemistry. 90, 4, p. 277-283 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Localization of cathepsins B, D, and L in the rat osteoclast by immuno-light and -electron microscopy

Goto, T., Tanaka, T., Kiyoshima, T., Moroi, R., Tsukuba, T., Yamamoto, K., Nishimura, Y. & Himeno, M., Jan 1 1994, In : Histochemistry. 101, 1, p. 33-40 8 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)

Long inverted repeat transiently stalls DNA replication by forming hairpin structures on both leading and lagging strands

Lai, P. J., Lim, C. T., Le, H. P., Katayama, T., Leach, D. R. F., Furukohri, A. & Maki, H., Feb 1 2016, In : Genes to Cells. 21, 2, p. 136-145 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Loss of Hda activity stimulates replication initiation from I-box, but not R4 mutant origins in Escherichia coli

Riber, L., Fujimitsu, K., Katayama, T. & Løbner-Olesen, A., Jan 1 2009, In : Molecular Microbiology. 71, 1, p. 107-122 16 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Lycocasuarines A–C, Lycopodium alkaloids from Lycopodiastrum casuarinoides

Wang, L. L., Zhou, Z. B., Zhu, X. L., Yuan, F. Y., Miyamoto, T. & Pan, K., Dec 27 2017, In : Tetrahedron Letters. 58, 52, p. 4827-4831 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Lycodine-type alkaloids and their glycosides from Lycopodiastrum casuarinoides

Wang, L. L., Hao, L. J., Zhou, Z. B., Zhu, X. L., Shi, Z. H., Miyamoto, T. & Pan, K., Oct 2018, In : Phytochemistry. 154, p. 63-72 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Lysosomal acid phosphatase is transported via endosomes to lysosomes

Tanaka, Y., Yano, S., Okada, K., Ishikawa, T., Himeno, M. & Kato, K., Feb 14 1990, In : Biochemical and Biophysical Research Communications. 166, 3, p. 1176-1182 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
24 Citations (Scopus)
17 Citations (Scopus)
1 Citation (Scopus)

Lysosomal storage disease

Tanaka, Y., Fujita, H. & Himeno, M., May 2004, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 49, 7 Suppl, p. 1143-1144 2 p.

Research output: Contribution to journalReview article

Magnesium and Ammonium-Potassium Lithospermates B, the Active Principles Having a Uremia-Preventive Effect from Salvia miltiorrhiza

Tanaka, T., Morimoto, S., Nonaka, G. I., Nishioka, I., Yokozawa, T., Chung, C., Oura, H. & Young, H., Jan 1 1989, In : Chemical and Pharmaceutical Bulletin. 37, 2, p. 340-344 5 p.

Research output: Contribution to journalArticle

115 Citations (Scopus)

Magnetic particles-based enzyme immunoassay for rapid determination of secoiridoid glycoside, amarogentin

Sakamoto, S., Wada, S., Morita, Y., Yamaguchi, T., Tanaka, H. & Morimoto, S., Mar 1 2019, In : Talanta. 194, p. 731-736 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Major cytochrome P450 enzyme responsible for oxidation of secondary alcohols to the corresponding ketones in mouse hepatic microsomes: Oxidation of 7-hydroxy-Δ8-tetrahydrocannabinol to 7-oxo-Δ8-tetrahydrocannabinol

Matsunaga, T., Kishi, N., Tanaka, H., Watanabe, K., Yoshimura, H. & Yamamoto, I., Oct 1 1998, In : Drug Metabolism and Disposition. 26, 10, p. 1045-1047 3 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Malignant transformation alters intracellular trafficking of lysosomal cathepsin D in human breast epithelial cells

Nishimura, Y., Sameni, M. & Sloane, B. F., Jan 1 1998, In : Pathology and Oncology Research. 4, 4, p. 283-296 14 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B

Fujita, H., Umezuki, Y., Imamura, K., Ishikawa, D., Uchimura, S., Nara, A., Yoshimori, T., Hayashizaki, Y., Kawai, J., Ishidoh, K., Tanaka, Y. & Himeno, M., Jun 15 2004, In : Journal of cell science. 117, 14, p. 2997-3009 13 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Massspectrometric analyses of transmembrane proteins in human erythrocyte membrane

Abe, Y., Chaen, T., Jin, X. R., Hamasaki, T. & Hamasaki, N., Jul 1 2004, In : Journal of biochemistry. 136, 1, p. 97-106 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Maternal exposure to dioxin disrupts gonadotropin production in fetal rats and imprints defects in sexual behavior

Takeda, T., Matsumoto, Y., Koga, T., Mutoh, J., Nishimura, Y., Shimazoe, T., Ishii, Y., Ishida, T. & Yamada, H., Jun 2009, In : Journal of Pharmacology and Experimental Therapeutics. 329, 3, p. 1091-1099 9 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Maternal exposure to dioxin imprints sexual immaturity of the pups through fixing the status of the reduced expression of hypothalamic gonadotropin- releasing hormone

Takeda, T., Fujii, M., Hattori, Y., Yamamoto, M., Shimazoe, T., Ishii, Y., Himeno, M. & Yamada, H., Jan 1 2014, In : Molecular Pharmacology. 85, 1, p. 74-82 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Maternal exposure to dioxin reduces hypothalamic but not pituitary metabolome in fetal rats: A possible mechanism for a fetus-specific reduction in steroidogenesis

Matsumoto, Y., Ishida, T., Takeda, T., Koga, T., Fujii, M., Ishii, Y., Fujimura, Y., Miura, D., Wariishi, H. & Yamada, H., Jan 1 2010, In : Journal of Toxicological Sciences. 35, 3, p. 365-373 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Mechanism for retardation of amyloid fibril formation by sugars in Vλ6 protein

Abe, M., Abe, Y., Ohkuri, T., Mishima, T., Monji, A., Kanba, S. & Ueda, T., Apr 1 2013, In : Protein Science. 22, 4, p. 467-474 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Mechanisms of a conversion from membrane associated lysosomal acid phosphatase to content forms

Himeno, M., Nakamura, K., Tanaka, Y., Yamada, H., Imoto, T. & Kato, K., Nov 14 1991, In : Biochemical and Biophysical Research Communications. 180, 3, p. 1483-1489 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
7 Citations (Scopus)

Melanin Biosynthesis Inhibitory and Antioxidant Activities of Quercetin-3′-0-jff-D-glucoside Isolated from Allium cepa

Arung, E. T., Shimizu, K., Kondo, R., Furuta, S., Ishikawa, H. & Tanaka, H., Jun 2011, In : Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 66, 5-6, p. 209-214 6 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Melanogenesis Inhibitors from the Endophytic Fungus Aspergillus amstelodami

Elsbaey, M., Sallam, A., El-Metwally, M., Nagata, M., Tanaka, C., Shimizu, K. & Miyamoto, T., Jan 1 2019, In : Chemistry and Biodiversity. 16, 8, e1900237.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Membrane-associated RING-CH (MARCH) 8 mediates the ubiquitination and lysosomal degradation of the transferrin receptor

Fujita, H., Iwabu, Y., Tokunaga, K. & Tanaka, Y., Jul 2013, In : Journal of cell science. 126, 13, p. 2798-2809 12 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Memorial address for Dr. Hideyuki Yamada, distinguished professor

Ishii, Y., Oct 1 2016, In : Drug Metabolism Reviews. 48, 4, p. 471-472 2 p.

Research output: Contribution to journalReview article

Metabolism of drugs of abuse: Its contribution to the toxicity and the inter-individual differences in drug sensitivity

Yamada, H., Ishii, Y. & Oguri, K., May 18 2005, In : Journal of Health Science. 51, 1, p. 1-7 7 p.

Research output: Contribution to journalShort survey

7 Citations (Scopus)

Metabolomic profiling of brain tissues of mice chronically exposed to heroin

Li, R. S., Takeda, T., Ohshima, T., Yamada, H. & Ishii, Y., Feb 2017, In : Drug Metabolism and Pharmacokinetics. 32, 1, p. 108-111 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Methyl jasmonate elicitation enhances glycyrrhizin production in glycyrrhiza inflata hairy roots cultures

Wongwicha, W., Tanaka, H., Shoyama, Y. & Putalun, W., Jan 1 2011, In : Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 66 C, 7-8, p. 423-428 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Micropropagation of Actinidia polygama from fruit galls

Tanaka, H., Shoyama, Y., Sasaki, Y. & Sashida, Y., 1997, In : Plant Cell, Tissue and Organ Culture. 48, 2, p. 135-137 3 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Micro-scale and rapid expression screening of highly expressed and/or stable membrane protein variants in Saccharomyces cerevisiae

Shiroishi, M., Moriya, M. & Ueda, T., Oct 1 2016, In : Protein Science. p. 1863-1872 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Microsomal alcohol oxygenase: Purification and characterization of a cytochrome P450 responsible for oxidation of 7-hydroxy-Δ8- tetrahydrocannabinol to 7-oxo-Δ8-tetrahydrocannabinol in guinea pig liver

Matsunaga, T., Tanaka, H., Komura, A., Watanabe, K., Yamamoto, I. & Yoshimura, H., Dec 1 1997, In : Archives of Biochemistry and Biophysics. 348, 1, p. 56-64 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Mitophagy: Selective degradation of mitochondria by autophagy

Hirota, Y., Aoki, Y. & Kanki, T., Dec 1 2011, In : Seikagaku. 83, 2, p. 126-130 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways

Hirota, Y., Yamashita, S. I., Kurihara, Y., Jin, X., Aihara, M., Saigusa, T., Kang, D. & Kanki, T., Jan 1 2015, In : Autophagy. 11, 2, p. 332-343 12 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)
161 Citations (Scopus)

Modes of overinitiation, dnaA gene expression, and inhibition of cell division in a novel cold-sensitive hda mutant of Escherichia coli

Fujimitsu, K., Su'etsugu, M., Yamaguchi, Y., Mazda, K., Fu, N., Kawakami, H. & Katayama, T., Aug 2008, In : Journal of bacteriology. 190, 15, p. 5368-5381 14 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Modification of the gluconeogenesis is not involved in the co-planar PCB toxicity in highly sensitive guinea pigs

Oguri, K., Hatsumura, M., Ishii, Y., Koga, Y., Ariyoshi, N. & Yoshimura, H., Dec 1993, In : Chemosphere. 27, 11, p. 2295-2303 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Modifications of stability and function of lysozyme

Imoto, T., Yamada, H., Okazaki, K., Ueda, T., Kuroki, R. & Yasukochi, T., Apr 1 1987, In : Journal of Protein Chemistry. 6, 2, p. 95-107 13 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Modulation of compactness and long-range interactions of unfolded lysozyme by single point mutations

Wirmer, J., Schlörb, C., Klein-Seetharaman, J., Hirano, R., Ueda, T., Imoto, T. & Schwalbe, H., Nov 5 2004, In : Angewandte Chemie - International Edition. 43, 43, p. 5780-5785 6 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Modulation of plumbagin production in Plumbago zeylanica using a single-chain variable fragment antibody against plumbagin

Sakamoto, S., Putalun, W., Pongkitwitoon, B., Juengwatanatrakul, T., Shoyama, Y., Tanaka, H. & Morimoto, S., Jan 1 2012, In : Plant Cell Reports. 31, 1, p. 103-110 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Modulation of UDP-glucuronosyltransferase 2B7 function by cytochrome P450s in vitro: Differential effects of CYP1A2, CYP2C9 and CYP3A4

Takeda, S., Ishii, Y., Mackenzie, P. I., Nagata, K., Yamazoe, Y., Oguri, K. & Yamada, H., Oct 1 2005, In : Biological and Pharmaceutical Bulletin. 28, 10, p. 2026-2027 2 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Modulation of UDP-glucuronosyltransferase activity by endogenous compounds

Ishii, Y., Nurrochmad, A. & Yamada, H., Jan 1 2010, In : Drug metabolism and pharmacokinetics. 25, 2, p. 134-148 15 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)

Modulation of UDP-glucuronosyltransferase activity by protein-protein association

Ishii, Y., Takeda, S. & Yamada, H., Feb 2010, In : Drug Metabolism Reviews. 42, 1, p. 145-158 14 p.

Research output: Contribution to journalReview article

39 Citations (Scopus)

Modulation of UDP-glucuronosyltransferase function by cytochrome P450: Evidence for the alteration of UGT2B7-catalyzed glucuronidation of morphine by CYP3A4

Takeda, S., Ishii, Y., Iwanaga, M., Mackenzie, P. I., Nagata, K., Yamazoe, Y., Oguri, K. & Yamada, H., Mar 2005, In : Molecular Pharmacology. 67, 3, p. 665-672 8 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Molecular basis and functional consequences of the dominant effects of the mutant band 3 on the structure of normal band 3 in Southeast Asian ovalocytosis

Kuma, H., Abe, Y., Askin, D., Bruce, L. J., Hamasaki, T., Tanner, M. J. A. & Hamasaki, N., Mar 12 2002, In : Biochemistry. 41, 10, p. 3311-3320 10 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Molecular basis for governing the morphology of type-I collagen fibrils by Osteomodulin

Tashima, T., Nagatoishi, S., Caaveiro, J. M. M., Nakakido, M., Sagara, H., Kusano-Arai, O., Iwanari, H., Mimuro, H., Hamakubo, T., Ohnuma, S. I. & Tsumoto, K., Dec 1 2018, In : Communications Biology. 1, 1, 33.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)