Research Center for Transomics Medicine

Research Output

64 Citations (Scopus)

Monoclonal antibodies 2F12H4 and 3C3F1 against mouse Pax7

Ohkawa, Y., Feb 1 2010, In : Hybridoma. 29, 1, 1 p.

Research output: Contribution to journalShort survey

Monoclonal antibodies 6D2 and 8H3 against mouse Chd2

Ohkawa, Y., Jun 1 2010, In : Hybridoma. 29, 3, 1 p.

Research output: Contribution to journalShort survey

Monoclonal antibody 1E2G4 against mouse Myf5

Ohkawa, Y., Feb 1 2010, In : Hybridoma. 29, 1, 1 p.

Research output: Contribution to journalShort survey

Monoclonal antibody 1H7A10 against mouse Brm

Ohkawa, Y., Feb 1 2010, In : Hybridoma. 29, 1, 1 p.

Research output: Contribution to journalShort survey

Monoclonal antibody 8E3 against mouse Dhx9/NDHII/RHA

Ohkawa, Y., Jun 1 2010, In : Hybridoma. 29, 3, 1 p.

Research output: Contribution to journalShort survey

Monoclonal antibody specific for Dhx9/NDHII/RHA

Kotani, M., Harada, A., Odawara, J., Azuma, M., Okada, S., Nishiyama, Y., Nakamura, M., Tachibana, T. & Ohkawa, Y., Jun 1 2010, In : Hybridoma. 29, 3, p. 259-261 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Mouse polycomb group gene Cbx2 promotes osteoblastic but suppresses adipogenic differentiation in postnatal long bones

Katoh-Fukui, Y., Baba, T., Sato, T., Otake, H., Nagakui-Noguchi, Y., Shindo, M., Suyama, M., Ohkawa, Y., Tsumura, H., Morohashi, K. I. & Fukami, M., Mar 2019, In : Bone. 120, p. 219-231 13 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

MTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide

Matsumoto, A., Pasut, A., Matsumoto, M., Yamashita, R., Fung, J., Monteleone, E., Saghatelian, A., Nakayama, K. I., Clohessy, J. G. & Pandolfi, P. P., Jan 12 2017, In : Nature. 541, 7636, p. 228-232 5 p.

Research output: Contribution to journalArticle

178 Citations (Scopus)

mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide.

Matsumoto, A., Pasut, A., Matsumoto, M., Yamashita, R., Fung, J., Monteleone, E., Saghatelian, A., Nakayama, K., Clohessy, J. & Pandolfi, P. P., 2017, In : Nature. 541, 7636, p. 228 5 p., 541.

Research output: Contribution to journalArticle

Mucosal dysbiosis in patients with gastrointestinal follicular lymphoma

Zeze, K., Hirano, A., Torisu, T., Esaki, M., Shibata, H., Moriyama, T., Umeno, J., Fujioka, S., Okamoto, Y., Fuyuno, Y., Matsuno, Y. & Kitazono, T., Apr 1 2020, In : Hematological Oncology. 38, 2, p. 181-188 8 p.

Research output: Contribution to journalArticle

Myeloperoxidase exacerbates secondary injury by generating highly reactive oxygen species and mediating neutrophil recruitment in experimental spinal cord injury

Kubota, K., Saiwai, H., Kumamaru, H., Maeda, T., Ohkawa, Y., Aratani, Y., Nagano, T., Iwamoto, Y. & Okada, S., Jul 15 2012, In : Spine. 37, 16, p. 1363-1369 7 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

MyoD targets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex

De La Serna, I. L., Ohkawa, Y., Berkes, C. A., Bergstrom, D. A., Dacwag, C. S., Tapscott, S. J. & Imbalzano, A. N., May 1 2005, In : Molecular and cellular biology. 25, 10, p. 3997-4009 13 p.

Research output: Contribution to journalArticle

194 Citations (Scopus)

Myogenic microRNA expression requires ATP-dependent chromatin remodeling enzyme function

Mallappa, C., Nasipak, B. T., Etheridge, L., Androphy, E. J., Jones, S. N., Sagerström, C. G., Ohkawa, Y. & Imbalzano, A. N., Jul 1 2010, In : Molecular and cellular biology. 30, 13, p. 3176-3186 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Nedd4-interacting protein 2, a short half-life membrane protein degraded in lysosomes, negatively controls down-regulation of connexin43

Ohzono, C., Etoh, S., Matsumoto, M., Nakayama, K. I., Hirota, Y., Tanaka, Y. & Fujita, H., Jun 17 2010, In : Biological and Pharmaceutical Bulletin. 33, 6, p. 951-957 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

New horizons in biological research developed by nextgeneration proteomics: Say good-bye to western blotting

Nakatsumi, H., Matsumoto, M. & Nakayama, K., Dec 1 2012, In : Seikagaku. 84, 1, p. 53-57 5 p.

Research output: Contribution to journalArticle

Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages

Nakatsumi, H., Matsumoto, M. & Nakayama, K. I., Nov 28 2017, In : Cell Reports. 21, 9, p. 2471-2486 16 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Novel localizations and interactions of intercellular bridge proteins revealed by proteomic profiling†

Iwamori, T., Iwamori, N., Matsumoto, M., Imai, H. & Ono, E., Apr 24 2020, In : Biology of reproduction. 102, 5, p. 1134-1144 11 p.

Research output: Contribution to journalArticle

Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36

Endo, A., Matsumoto, M., Inada, T., Yamamoto, A., Nakayama, K. I., Kitamura, N. & Komada, M., Mar 1 2009, In : Journal of cell science. 122, 5, p. 678-686 9 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Opposing calcium-dependent signalling pathways control skeletal muscle differentiation by regulating a chromatin remodelling enzyme

Nasipak, B. T., Padilla-Benavides, T., Green, K. M., Leszyk, J. D., Mao, W., Konda, S., Sif, S., Shaffer, S. A., Ohkawa, Y. & Imbalzano, A. N., Jun 17 2015, In : Nature communications. 6, 7441.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Ossification of the posterior longitudinal ligament of the lumbar spine: A case series

Okada, S., Maeda, T., Saiwai, H., Ohkawa, Y., Shiba, K. & Iwamoto, Y., Nov 1 2010, In : Neurosurgery. 67, 5, p. 1311-1318 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Overexpression of Ephrin A2 receptors in cancer stromal cells is a prognostic factor for the relapse of gastric cancer

Kikuchi, S., Kaibe, N., Morimoto, K., Fukui, H., Niwa, H., Maeyama, Y., Takemura, M., Matsumoto, M., Nakamori, S., Miwa, H., Hirota, S. & Sasako, M., Jul 27 2015, In : Gastric Cancer. 18, 3, p. 485-494 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Partial SPAST and DPY30 deletions in a Japanese spastic paraplegia type 4 family

Miura, S., Shibata, H., Kida, H., Noda, K., Toyama, T., Iwasaki, N., Iwaki, A., Ayabe, M., Aizawa, H., Taniwaki, T. & Fukumaki, Y., Feb 1 2011, In : Neurogenetics. 12, 1, p. 25-31 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Pathological changes of distal motor neurons after complete spinal cord injury

Yokota, K., Kubota, K., Kobayakawa, K., Saito, T., Hara, M., Kijima, K., Maeda, T., Katoh, H., Ohkawa, Y., Nakashima, Y. & Okada, S., Jan 9 2019, In : Molecular Brain. 12, 1, 4.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Performance of small-domain monolithic silica columns in nano-liquid chromatography and comparison with commercial packed bed columns with 2 µm particles

Hara, T., Izumi, Y., Hata, K., Baron, V. G., Bamba, T. & Desmet, G., Apr 12 2020, In : Journal of Chromatography A. 1616, 460804.

Research output: Contribution to journalArticle

Periostin Promotes Scar Formation through the Interaction between Pericytes and Infiltrating Monocytes/Macrophages after Spinal Cord Injury

Yokota, K., Kobayakawa, K., Saito, T., Hara, M., Kijima, K., Ohkawa, Y., Harada, A., Okazaki, K., Ishihara, K., Yoshida, S., Kudo, A., Iwamoto, Y. & Okada, S., Mar 1 2017, In : American Journal of Pathology. 187, 3, p. 639-653 15 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Persistent detection of alternatively spliced BCR-ABL variant results in a failure to achieve deep molecular response

Yuda, J., Miyamoto, T., Odawara, J., Ohkawa, Y., Semba, Y., Hayashi, M., Miyamura, K., Tanimoto, M., Yamamoto, K., Taniwaki, M. & Akashi, K., Nov 2017, In : Cancer Science. 108, 11, p. 2204-2212 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Phosphoproteomics analyses show subnetwork systems in T-cell receptor signaling

Hatano, A., Matsumoto, M. & Nakayama, K. I., Oct 1 2016, In : Genes to Cells. 21, 10, p. 1095-1112 18 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Phosphorylation of Noxo1 at threonine 341 regulates its interaction with Noxa1 and the superoxide-producing activity of Nox1

Yamamoto, A., Takeya, R., Matsumoto, M., Nakayama, K. I. & Sumimoto, H., Oct 1 2013, In : FEBS Journal. 280, 20, p. 5145-5159 15 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Phosphorylation of the chromodomain changes the binding specificity of Cbx2 for methylated histone H3

Hatano, A., Matsumoto, M., Higashinakagawa, T. & Nakayama, K. I., Jun 18 2010, In : Biochemical and Biophysical Research Communications. 397, 1, p. 93-99 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth

Morita, M., Sato, T., Nomura, M., Sakamoto, Y., Inoue, Y., Tanaka, R., Ito, S., Kurosawa, K., Yamaguchi, K., Sugiura, Y., Takizaki, H., Yamashita, Y., Katakura, R., Sato, I., Kawai, M., Okada, Y., Watanabe, H., Kondoh, G., Matsumoto, S., Kishimoto, A. & 12 others, Obata, M., Matsumoto, M., Fukuhara, T., Motohashi, H., Suematsu, M., Komatsu, M., Nakayama, K. I., Watanabe, T., Soga, T., Shima, H., Maemondo, M. & Tanuma, N., Mar 12 2018, In : Cancer Cell. 33, 3, p. 355-367.e7

Research output: Contribution to journalArticle

32 Citations (Scopus)

Planteose as a storage carbohydrate required for early stage of germination of Orobanche minor and its metabolism as a possible target for selective control

Wakabayashi, T., Joseph, B., Yasumoto, S., Akashi, T., Aoki, T., Harada, K., Muranaka, S., Bamba, T., Fukusaki, E., Takeuchi, Y., Yoneyama, K., Muranaka, T., Sugimoto, Y. & Okazawa, A., Jun 1 2015, In : Journal of Experimental Botany. 66, 11, p. 3085-3097 13 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Plasma gelsolin facilitates interaction between β2 glycoprotein I and α5β1 integrin

Bohgaki, M., Matsumoto, M., Atsumi, T., Kondo, T., Yasuda, S., Horita, T., Nakayama, K. I., Okumura, F., Hatakeyama, S. & Koike, T., Jan 1 2011, In : Journal of Cellular and Molecular Medicine. 15, 1, p. 141-151 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Polymorphism analysis of the upstream region of the human N-methyl-D-aspartate receptor subunit NR1 gene (GRIN1): Implications for schizophrenia

Tani, A., Kikuta, R., Itoh, K., Joo, A., Shibata, H., Ninomiya, H., Tashiro, N. & Fukumaki, Y., Nov 1 2002, In : Schizophrenia research. 58, 1, p. 83-86 4 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Positive association of Phencyclidine-responsive genes, PDE4A and PLAT, with schizophrenia

Deng, X., Takaki, H., Wang, L., Kuroki, T., Nakahara, T., Hashimoto, K., Ninomiya, H., Arinami, T., Inada, T., Ujike, H., Itokawa, M., Tochigi, M., Watanabe, Y., Someya, T., Kunugi, H., Iwata, N., Ozaki, N., Shibata, H. & Fukumaki, Y., Dec 1 2011, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 156, 7, p. 850-858 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Positive association of the AMPA receptor subunit GluR4 gene (GRIA4) haplotype with schizophrenia: Linkage disequilibrium mapping using SNPs evenly distributed across the gene region

Makino, C., Fujii, Y., Kikuta, R., Hirata, N., Tani, A., Shibata, A., Ninomiya, H., Tashiro, N., Shibata, H. & Fukumaki, Y., Jan 1 2003, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 116 B, 1, p. 17-22 6 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Positive associations of polymorphisms in the metabotropic glutamate receptor type 3 gene (GRM3) with schizophrenia

Fujii, Y., Shibata, H., Kikuta, R., Makino, C., Tani, A., Hirata, N., Shibata, A., Ninomiya, H., Tashiro, N. & Fukumaki, Y., Jun 2003, In : Psychiatric Genetics. 13, 2, p. 71-76 6 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)

Positive associations of polymorphisms in the metabotropic glutamate receptor type 8 gene (GRM8) with schizophrenia

Takaki, H., Kikuta, R., Shibata, H., Ninomiya, H., Tashiro, N. & Fukumaki, Y., Jul 1 2004, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 128 B, 1, p. 6-14 9 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Prediction of periodontal inflammation via metabolic profiling of saliva

Kuboniwa, M., Sakanaka, A., Hashino, E., Bamba, T., Fukusaki, E. & Amano, A., Nov 1 2016, In : Journal of Dental Research. 95, 12, p. 1381-1386 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Preferential interaction of TIP120A with Cul1 that is not modified by NEDD8 and not associated with Skp1

Oshikawa, K., Matsumoto, M., Yada, M., Kamura, T., Hatakeyama, S. & Nakayama, K. I., Apr 18 2003, In : Biochemical and Biophysical Research Communications. 303, 4, p. 1209-1216 8 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Production of a rat monoclonal antibody against Brg1

Ohkawa, Y., Harada, A., Nakamura, M., Yoshimura, S. & Tachibana, T., Dec 1 2009, In : Hybridoma. 28, 6, p. 463-466 4 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Production of a rat monoclonal antibody specific for Myf5

Harada, A., Okada, S., Odawara, J., Kumamaru, H., Saiwai, H., Aoki, M., Nakamura, M., Nishiyama, Y. & Ohkawa, Y., Feb 1 2010, In : Hybridoma. 29, 1, p. 59-62 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Production of BBF2H7-derived small peptide fragments via endoplasmic reticulum stress-dependent regulated intramembrane proteolysis

Matsuhisa, K., Saito, A., Cai, L., Kaneko, M., Okamoto, T., Sakaue, F., Asada, R., Urano, F., Yanagida, K., Okochi, M., Kudo, Y., Matsumoto, M., Nakayama, K. I. & Imaizumi, K., Jan 1 2020, In : FASEB Journal. 34, 1, p. 865-880 16 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Prolonged inhibition of hepatocellular carcinoma cell proliferation by combinatorial expression of defined transcription factors

Takashima, Y., Horisawa, K., Udono, M., Ohkawa, Y. & Suzuki, A., Nov 2018, In : Cancer Science. 109, 11, p. 3543-3553 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Protection of stromal cell-derived factor 2 by heat shock protein 72 prevents oxaliplatin-induced cell death in oxaliplatin-resistant human gastric cancer cells

Takahashi, K., Tanaka, M., Yashiro, M., Matsumoto, M., Ohtsuka, A., Nakayama, K. I., Izumi, Y., Nagayama, K., Miura, K., Iwao, H. & Shiota, M., Aug 1 2016, In : Cancer Letters. 378, 1, p. 8-15 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Proteome of ubiquitin/MVB pathway: Possible involvement of iron-induced ubiquitylation of transferrin receptor in lysosomal degradation

Tachiyama, R., Ishikawa, D., Matsumoto, M., Nakayama, K. I., Yoshimori, T., Yokota, S., Himeno, M., Tanaka, Y. & Fujita, H., Apr 1 2011, In : Genes to Cells. 16, 4, p. 448-466 19 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin

Oshikawa, K., Matsumoto, M., Oyamada, K. & Nakayama, K. I., Feb 3 2012, In : Journal of Proteome Research. 11, 2, p. 796-807 12 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
71 Citations (Scopus)