Research & Clinical Center for Yusho & Dioxin

Research Output 2001 2019

2019

A Case of Atrophic Dermatofibroma Overexpressing Matrix Metalloproteinase-1

Yano-Takamori, A., Tsuji, G., Nakahara, T., Kido-Nakahara, M. & Furue, M., Sep 1 2019, In : Case Reports in Dermatology. 11, 3, p. 264-267 4 p.

Research output: Contribution to journalArticle

Open Access
Benign Fibrous Histiocytoma
Matrix Metalloproteinase 1
Differential Diagnosis
Neoplasms
Keratinocytes
Fermentation
Down-Regulation
Antioxidants
Chemical activation

Aryl hydrocarbon receptor in atopic dermatitis and psoriasis

Furue, M., Hashimoto-Hachiya, A. & Tsuji, G., Nov 1 2019, In : International journal of molecular sciences. 20, 21, 5424.

Research output: Contribution to journalReview article

Open Access
dermatitis
Aryl Hydrocarbon Receptors
Atopic Dermatitis
Psoriasis
Aryl Hydrocarbon Receptor Nuclear Translocator
Open Access
Chloracne
Aryl Hydrocarbon Receptors
Hyperpigmentation
Dioxins
Melanocytes
2 Citations (Scopus)

Cross-sectional multicenter observational study of psoriatic arthritis in Japanese patients: Relationship between skin and joint symptoms and results of treatment with tumor necrosis factor-α inhibitors

Tsuruta, N., Narisawa, Y., Imafuku, S., Ito, K., Yamaguchi, K., Miyagi, T., Takahashi, K., Fukamatsu, H., Morizane, S., Koketsu, H., Yamaguchi, M., Hino, R., Nakamura, M., Ohyama, B., Ohata, C., Kuwashiro, M., Sato, T., Saito, K., Kaneko, S., Yonekura, K. & 10 others, Hayashi, H., Yanase, T., Morimoto, K., Sugita, K., Yanagihara, S., Kikuchi, S., Mitoma, C., Nakahara, T., Furue, M. & Okazaki, F., Mar 2019, In : Journal of Dermatology. 46, 3, p. 193-198 6 p.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Multicenter Studies
Observational Studies
Tumor Necrosis Factor-alpha
Joints
3 Citations (Scopus)

Cyto/chemokine profile of in vitro scratched keratinocyte model: Implications of significant upregulation of CCL20, CXCL8 and IL36G in Koebner phenomenon

Furue, K., Ito, T., Tanaka, Y., Yumine, A., Hashimoto-Hachiya, A., Takemura, M., Murata, M., Yamamura, K., Tsuji, G. & Furue, M., Apr 2019, In : Journal of Dermatological Science. 94, 1, p. 244-251 8 p.

Research output: Contribution to journalArticle

Keratinocytes
Chemokines
Psoriasis
Up-Regulation
Benzo(a)pyrene

Does mechanical scratching cause the recruitment of T-helper 17 cells in atopic dermatitis?

Furue, K., Ito, T., Tsuji, G., Esaki, H., Kido-Nakahara, M., Nakahara, T. & Furue, M., Nov 1 2019, In : Journal of Dermatology. 46, 11, p. e436-e437

Research output: Contribution to journalLetter

Th17 Cells
Atopic Dermatitis
1 Citation (Scopus)
Open Access
dermatitis
Atopic Dermatitis
Interleukin-4
Dendritic Cells
bone marrow
4 Citations (Scopus)

Implications of tryptophan photoproduct FICZ in oxidative stress and terminal differentiation of keratinocytes

Furue, M., Uchi, H., Mitoma, C., Hashimoto-Hachiya, A., Tanaka, Y., Ito, T. & Tsuji, G., Feb 2019, In : Giornale Italiano di Dermatologia e Venereologia. 154, 1, p. 37-41 5 p.

Research output: Contribution to journalReview article

Aryl Hydrocarbon Receptors
Keratinocytes
Tryptophan
Reactive Oxygen Species
Oxidative Stress
2 Citations (Scopus)

Pathogenesis of Atopic Dermatitis: Current Paradigm

Furue, M., Ulzii, D., Vu, Y. H., Tsuji, G., Kido-Nakahara, M. & Nakahara, T., Jun 1 2019, In : Iranian journal of immunology : IJI. 16, 2, p. 97-107 11 p.

Research output: Contribution to journalReview article

Interleukin-13
Atopic Dermatitis
Interleukin-4
Keratinocytes
Interleukin-4 Receptors
2 Citations (Scopus)

Potential role of PM2.5 in melanogenesis

Peng, F., Tsuji, G., Zhang, J. Z., Chen, Z. & Furue, M., Nov 2019, In : Environment International. 132, 105063.

Research output: Contribution to journalReview article

Open Access
particulate matter
skin
homeostasis
hydrocarbon
PAH
2 Citations (Scopus)

Psoriasis and the TNF/IL23/IL17 axis

Furue, K., Ito, T., Tsuji, G., Kadono, T. & Furue, M., Aug 1 2019, In : Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia. 154, 4, p. 418-424 7 p.

Research output: Contribution to journalArticle

Psoriasis
Interleukin-17
Biological Products
Keratinocytes
Interleukin-23

Pulmonary thromboembolism induced by intravenous immunoglobulin therapy for Stevens-Johnson syndrome: A case report

Ide, T., Ohno, M., Ito, T., Tsukamoto, K., Hirano, A., Sonoyama, H., Nakano, T., Furue, M. & Mashino, T., Jan 1 2019, In : Nishinihon Journal of Dermatology. 81, 3, p. 170-174 5 p.

Research output: Contribution to journalArticle

Stevens-Johnson Syndrome
Passive Immunization
Intravenous Immunoglobulins
Pulmonary Embolism
Tarsal Bones

Scratching counteracts il-13 signaling by upregulating the decoy receptor il-13rα2 in keratinocytes

Ulzii, D., Kido-Nakahara, M., Nakahara, T., Tsuji, G., Furue, K., Hashimoto-Hachiya, A. & Furue, M., Jul 1 2019, In : International journal of molecular sciences. 20, 13, 3324.

Research output: Contribution to journalArticle

Open Access
decoys
Interleukin-13
Keratinocytes
Interleukin-13 Receptors
dermatitis

Serum squamous cell carcinoma antigen (SCCA)-2 correlates with clinical severity of pediatric atopic dermatitis in Ishigaki cohort

Takeuchi, S., Furusyo, N., Ono, J., Azuma, Y., Takemura, M., Esaki, H., Yamamura, K., Mitamura, Y., Tsuji, G., Kiyomatsu-Oda, M., Hayashi, J., Izuhara, K. & Furue, M., Aug 2019, In : Journal of Dermatological Science. 95, 2, p. 70-75 6 p.

Research output: Contribution to journalArticle

Pediatrics
Atopic Dermatitis
Chemokine CCL17
Serum
Dermatitis

Successful treatment of acrodermatitis continua of Hallopeau with apremilast

Kurihara, Y., Nakano, K., Eto, A. & Furue, M., Oct 1 2019, In : Journal of Dermatology. 46, 10, p. e370-e371

Research output: Contribution to journalLetter

Acrodermatitis
apremilast

The IL-13–OVOL1–FLG axis in atopic dermatitis

Furue, K., Ito, T., Tsuji, G., Ulzii, D., Vu, Y. H., Kido-Nakahara, M., Nakahara, T. & Furue, M., Dec 1 2019, In : Immunology. 158, 4, p. 281-286 6 p.

Research output: Contribution to journalReview article

Open Access
Interleukin-13
Atopic Dermatitis
Interleukin-4 Receptors
Interleukin-4
Genome-Wide Association Study
1 Citation (Scopus)

Three cases of palmoplantar pustulosis successfully treated with apremilast

Eto, A., Nakao, M. & Furue, M., Jan 2019, In : Journal of Dermatology. 46, 1, p. e29-e30

Research output: Contribution to journalLetter

apremilast
1 Citation (Scopus)

Thrombocytopenia in a psoriatic patient sequentially treated with adalimumab, secukinumab and ustekinumab

Nakahara, T., Konishi, S., Yasukochi, Y., Esaki, H., Tsuji, G., Kido-Nakahara, M. & Furue, M., May 2019, In : Journal of Dermatology. 46, 5, p. e157-e158

Research output: Contribution to journalLetter

Thrombocytopenia
Adalimumab
Ustekinumab
secukinumab
2018

A case of recalcitrant chronic urticaria successfully controlled by warfarin

Maehara, E., Mitoma, C., Takamatsu, H., Harada, K., Wada, N., Matsuda, T., Ishida, N., Imayama, S. & Urabe, K., Jan 1 2018, In : Nishinihon Journal of Dermatology. 80, 1, p. 15-19 5 p.

Research output: Contribution to journalArticle

Urticaria
Warfarin
Cyclosporine
Famotidine
Thrombin

A case of recurrent cutaneous Mycobacterium chelonae infection after treatment

Eto, A., Nakamura, M., Ito, S., Tanaka, M., Tsuji, G., Matsuda, T. & Furue, M., Jan 1 2018, In : Nishinihon Journal of Dermatology. 80, 6, p. 546-549 4 p.

Research output: Contribution to journalArticle

Mycobacterium chelonae
Mycobacterium Infections
Skin
Anti-Bacterial Agents
Infection

A case of unilateral Darier's disease

Isotani, T., Kimura, N., Shigyou, A., Kiryu, H. & Furue, M., Jan 1 2018, In : Nishinihon Journal of Dermatology. 80, 2, p. 113-116 4 p.

Research output: Contribution to journalArticle

Darier Disease
Etretinate
Skin
Cholecalciferol
Nails
1 Citation (Scopus)

Accumulation properties of polychlorinated biphenyl congeners in Yusho patients and prediction of their cytochrome P450-dependent metabolism by in silico analysis

Hirakawa, S., Miyawaki, T., Hori, T., Kajiwara, J., Katsuki, S., Hirano, M., Yoshinouchi, Y., Iwata, H., Mitoma, C. & Furue, M., Jun 1 2018, In : Environmental Science and Pollution Research. 25, 17, p. 16455-16463 9 p.

Research output: Contribution to journalArticle

Polychlorinated Biphenyls
Polychlorinated biphenyls
Metabolism
Computer Simulation
Cytochrome P-450 Enzyme System

Acquired perforating collagenosis in a non-diabetic patient with advanced prostate carcinoma: A review of perforating dermatosis associated with malignancy

Kawahara, S., Mitoma, C., Murai, M. & Furue, M., Aug 2018, In : Journal of Dermatology. 45, 8, p. e219-e220

Research output: Contribution to journalLetter

Skin Diseases
Prostate
Carcinoma
Neoplasms
12 Citations (Scopus)

An endogenous tryptophan photo-product, FICZ, is potentially involved in photo-aging by reducing TGF-β-regulated collagen homeostasis

Murai, M., Tsuji, G., Hashimoto-Hachiya, A., Kawakami, Y., Furue, M. & Mitoma, C., Jan 2018, In : Journal of Dermatological Science. 89, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Procollagen
Tryptophan
Collagen Type I
Aryl Hydrocarbon Receptors
6 Citations (Scopus)

Bullous pemphigoid induced by ipilimumab in a patient with metastatic malignant melanoma after unsuccessful treatment with nivolumab

Kuwatsuka, Y., Iwanaga, A., Kuwatsuka, S., Okubo, Y., Murayama, N., Ishii, N., Hashimoto, T. & Utani, A., Jan 1 2018, In : Journal of Dermatology. 45, 1, p. e21-e22

Research output: Contribution to journalLetter

Bullous Pemphigoid
Melanoma
Therapeutics
ipilimumab
nivolumab
5 Citations (Scopus)

Case of angiosarcoma of the scalp successfully controlled by eribulin

Wada, N., Uchi, H. & Furue, M., Jan 2018, In : Journal of Dermatology. 45, 1, p. 116-117 2 p.

Research output: Contribution to journalLetter

eribulin
Hemangiosarcoma
Scalp
3 Citations (Scopus)

Clinical condition and management of 114 mamushi (Gloydius blomhoffii) bites in a general hospital in Japan

Chiba, T., Koga, H., Kimura, N., Murata, M., Jinnai, S., Suenaga, A., Kohda, F. & Furue, M., Jan 1 2018, In : Internal Medicine. 57, 8, p. 1075-1080 6 p.

Research output: Contribution to journalArticle

Snake Bites
Bites and Stings
General Hospitals
Japan
Literature

Compound-specific isotopic and congener-specific analyses of polychlorinated biphenyl in the heat medium and rice oil of the Yusho incident

Miyawaki, T., Sugihara, M., Hirakawa, S., Hori, T., Kajiwara, J., Katsuki, S., Mitoma, C. & Furue, M., Jun 1 2018, In : Environmental Science and Pollution Research. 25, 17, p. 16464-16471 8 p.

Research output: Contribution to journalArticle

Polychlorinated Biphenyls
Polychlorinated biphenyls
heat transfer
PCB
Oils

Corrigendum to “Familial primary localized cutaneous amyloidosis in a Japanese family” [J. Dermatol. Sci. 83 (2016) 162–164](S0923181116300779)(10.1016/j.jdermsci.2016.05.007)

Ueo, D., Utani, A., Okubo, Y., Yozaki, M., Mine, Y., Anan, T., Nishida, H., Takahashi, D., Sakai, T., Hatano, Y. & Fujiwara, S., Jan 1 2018, In : Journal of Dermatological Science. 89, 1, 1 p.

Research output: Contribution to journalComment/debate

Missense Mutation
Mutation
Exons
Substitution reactions
DNA

Crystallization granuloma by nifekalant hydrochloride infusion

Ichiki, T., Wada, M., Yasukouchi, Y., Nakahara, T., Mitoma, C., Hiroshi, U., Nishizaki, A., Mukai, Y. & Furue, M., Jul 1 2018, In : Geriatrics and Gerontology International. 18, 7, p. 1133-1134 2 p.

Research output: Contribution to journalLetter

Crystallization
Granuloma
nifekalant
3 Citations (Scopus)

Current state of yusho and prospects for therapeutic strategies

Mitoma, C., Uchi, H., Tsukimori, K., Todaka, T., Kajiwara, J., Shimose, T., Akahane, M., Imamura, T. & Furue, M., Jun 1 2018, In : Environmental Science and Pollution Research. 25, 17, p. 16472-16480 9 p.

Research output: Contribution to journalArticle

Dioxins
dioxin
Toxicity
Chelation
Bioactivity
18 Citations (Scopus)

Highlighting interleukin-36 signalling in plaque psoriasis and pustular psoriasis

Furue, K., Yamamura, K., Tsuji, G., Mitoma, C., Uchi, H., Nakahara, T., Kido-Nakahara, M., Kadono, T. & Furue, M., Jan 1 2018, In : Acta Dermato-Venereologica. 98, 1, p. 5-13 9 p.

Research output: Contribution to journalReview article

Interleukins
Psoriasis
Interleukin-23
Interleukin-17
Interleukin Receptors
6 Citations (Scopus)

Long-Term Health Effects of PCBs and Related Compounds: A Comparative Analysis of Patients Suffering from Yusho and the General Population

Akahane, M., Matsumoto, S., Kanagawa, Y., Mitoma, C., Uchi, H., Yoshimura, T., Furue, M. & Imamura, T., Feb 1 2018, In : Archives of Environmental Contamination and Toxicology. 74, 2, p. 203-217 15 p.

Research output: Contribution to journalArticle

Polychlorinated Biphenyls
Polychlorinated biphenyls
Health
Population
Aging of materials
10 Citations (Scopus)

Melanoma and Immune Checkpoint Inhibitors

Furue, M., Ito, T., Wada, N., Wada, M., Kadono, T. & Hiroshi, U., Mar 1 2018, In : Current Oncology Reports. 20, 3, 29.

Research output: Contribution to journalReview article

Melanoma
Survival
Disease-Free Survival
Quality of Life
Clinical Trials

Necrobiosis lipoidica with mucin deposition in a patient with autoimmune thyroiditis

Take, N., Mitoma, C. & Furue, M., Jul 2018, In : Journal of Dermatology. 45, 7, p. e193-e194

Research output: Contribution to journalLetter

Necrobiosis Lipoidica
Autoimmune Thyroiditis
Mucins
3 Citations (Scopus)
Fibroblasts
Chemical activation
Interleukin-13
Skin
Oxidative stress
Porokeratosis
Proteins
4 Citations (Scopus)

Perillaldehyde Inhibits AHR Signaling and Activates NRF2 Antioxidant Pathway in Human Keratinocytes

Fuyuno, Y., Uchi, H., Yasumatsu, M., Morino-Koga, S., Tanaka, Y., Mitoma, C. & Furue, M., Jan 1 2018, In : Oxidative medicine and cellular longevity. 2018, 1 p.

Research output: Contribution to journalArticle

Open Access
Aryl Hydrocarbon Receptors
Keratinocytes
Heme Oxygenase-1
Antioxidants
Reactive Oxygen Species
6 Citations (Scopus)

Protective role of peroxisome proliferator-activated receptor α agonists in skin barrier and inflammation

Furue, K., Mitoma, C., Tsuji, G. & Furue, M., Mar 1 2018, In : Immunobiology. 223, 3, p. 327-330 4 p.

Research output: Contribution to journalReview article

Peroxisome Proliferator-Activated Receptors
Inflammation
Skin
Protein Isoforms
Eczema

Recurrent varicella in a patient with systemic lupus erythematosus treated with immunosuppressants

Kimura, N., Urabe, K. & Furue, M., Jan 1 2018, In : Nishinihon Journal of Dermatology. 80, 4, p. 354-357 4 p.

Research output: Contribution to journalArticle

Human Herpesvirus 3
Chickenpox
Immunosuppressive Agents
Systemic Lupus Erythematosus
Simplexvirus
1 Citation (Scopus)

Sleep disorders among Yusho patients highly intoxicated with dioxin-related compounds: A 140-case series

Kondo, H., Tanio, K., Nagaura, Y., Nagayoshi, M., Mitoma, C., Furue, M. & Maeda, T., Oct 1 2018, In : Environmental Research. 166, p. 261-268 8 p.

Research output: Contribution to journalArticle

Restless Legs Syndrome
Dioxins
sleep
dioxin
Sleep
6 Citations (Scopus)

Therapeutic agents with AHR inhibiting and NRF2 activating activity for managing chloracne

Furue, M., Fuyuno, Y., Mitoma, C., Uchi, H. & Tsuji, G., Jul 13 2018, In : Antioxidants. 7, 7, 90.

Research output: Contribution to journalReview article

Chloracne
Aryl Hydrocarbon Receptors
Dioxins
Kampo Medicine
Health hazards
9 Citations (Scopus)

The role of the OVOL1–OVOL2 axis in normal and diseased human skin

Tsuji, G., Ito, T., Chiba, T., Mitoma, C., Nakahara, T., Uchi, H. & Furue, M., Jun 2018, In : Journal of Dermatological Science. 90, 3, p. 227-231 5 p.

Research output: Contribution to journalReview article

Atopic Dermatitis
Skin Diseases
Skin
Genes
Tissue
5 Citations (Scopus)

Tryptophan photo-product FICZ upregulates AHR/MEK/ERK-mediated MMP1 expression: Implications in anti-fibrotic phototherapy

Murai, M., Yamamura, K., Hashimoto-Hachiya, A., Tsuji, G., Furue, M. & Mitoma, C., Jul 2018, In : Journal of Dermatological Science. 91, 1, p. 97-103 7 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinases
Aryl Hydrocarbon Receptors
Phototherapy
Microtubule-Associated Proteins
Extracellular Signal-Regulated MAP Kinases
2017
8 Citations (Scopus)

6-Formylindolo[3,2-b]Carbazole Accelerates Skin Wound Healing via Activation of ERK, but Not Aryl Hydrocarbon Receptor

Morino-Koga, S., Uchi, H., Mitoma, C., Wu, Z., Kiyomatsu, M., Fuyuno, Y., Nagae, K., Yasumatsu, M., Suico, M. A., Kai, H. & Furue, M., Oct 2017, In : Journal of Investigative Dermatology. 137, 10, p. 2217-2226 10 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Wound Healing
Skin
Chemical activation
Keratinocytes

A case of angiosarcoma successfully treated with chemoradiation therapy

Nakaie, R., Mitoma, C., Takahara, M., Uchi, H. & Furue, M., Jan 1 2017, In : Nishinihon Journal of Dermatology. 79, 5, p. 482-486 5 p.

Research output: Contribution to journalArticle

docetaxel
Hemangiosarcoma
Neoplasms
Head
Paclitaxel

A case of cutaneous polyarteritis nodosa improved by drinking bidens pilosa tea as an alternative therapy

Nakagawa, R., Ichiki, T., Jinnai, S., Kohda, F., Mitoma, C. & Furue, M., Jan 1 2017, In : Nishinihon Journal of Dermatology. 79, 1, p. 24-27 4 p.

Research output: Contribution to journalArticle

Bidens
Polyarteritis Nodosa
Tea
Complementary Therapies
Drinking

A case of giant rhinophyma treated by surgical excision

Usagawa, Y., Mitoma, C., Wada, N., Uchi, H. & Furue, M., Jan 1 2017, In : Nishinihon Journal of Dermatology. 79, 4, p. 345-348 4 p.

Research output: Contribution to journalArticle

Rhinophyma
Nose
Sebaceous Glands
Neoplasms
Suppuration

A case of non-pigmented basal cell carcinoma on the dorsum of the nose

Maemura, H., Kimura, N., Takamatsu, H., Harada, K., Urabe, K. & Furue, M., Jan 1 2017, In : Nishinihon Journal of Dermatology. 79, 4, p. 371-375 5 p.

Research output: Contribution to journalArticle

Melanocytes
Basal Cell Carcinoma
Nose
MART-1 Antigen
Dermoscopy