Research & Clinical Center for Yusho & Dioxin

Research Output 2001 2019

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2019

A Case of Atrophic Dermatofibroma Overexpressing Matrix Metalloproteinase-1

Yano-Takamori, A., Tsuji, G., Nakahara, T., Kido-Nakahara, M. & Furue, M., Sep 1 2019, In : Case Reports in Dermatology. 11, 3, p. 264-267 4 p.

Research output: Contribution to journalArticle

Open Access
Benign Fibrous Histiocytoma
Matrix Metalloproteinase 1
Differential Diagnosis
Neoplasms
2 Citations (Scopus)

Cross-sectional multicenter observational study of psoriatic arthritis in Japanese patients: Relationship between skin and joint symptoms and results of treatment with tumor necrosis factor-α inhibitors

Tsuruta, N., Narisawa, Y., Imafuku, S., Ito, K., Yamaguchi, K., Miyagi, T., Takahashi, K., Fukamatsu, H., Morizane, S., Koketsu, H., Yamaguchi, M., Hino, R., Nakamura, M., Ohyama, B., Ohata, C., Kuwashiro, M., Sato, T., Saito, K., Kaneko, S., Yonekura, K. & 10 others, Hayashi, H., Yanase, T., Morimoto, K., Sugita, K., Yanagihara, S., Kikuchi, S., Mitoma, C., Nakahara, T., Furue, M. & Okazaki, F., Mar 2019, In : Journal of Dermatology. 46, 3, p. 193-198 6 p.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Multicenter Studies
Observational Studies
Tumor Necrosis Factor-alpha
Joints
3 Citations (Scopus)

Cyto/chemokine profile of in vitro scratched keratinocyte model: Implications of significant upregulation of CCL20, CXCL8 and IL36G in Koebner phenomenon

Furue, K., Ito, T., Tanaka, Y., Yumine, A., Hashimoto-Hachiya, A., Takemura, M., Murata, M., Yamamura, K., Tsuji, G. & Furue, M., Apr 2019, In : Journal of Dermatological Science. 94, 1, p. 244-251 8 p.

Research output: Contribution to journalArticle

Keratinocytes
Chemokines
Psoriasis
Up-Regulation
Benzo(a)pyrene
1 Citation (Scopus)
Open Access
dermatitis
Atopic Dermatitis
Interleukin-4
Dendritic Cells
bone marrow
2 Citations (Scopus)

Psoriasis and the TNF/IL23/IL17 axis

Furue, K., Ito, T., Tsuji, G., Kadono, T. & Furue, M., Aug 1 2019, In : Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia. 154, 4, p. 418-424 7 p.

Research output: Contribution to journalArticle

Psoriasis
Interleukin-17
Biological Products
Keratinocytes
Interleukin-23

Pulmonary thromboembolism induced by intravenous immunoglobulin therapy for Stevens-Johnson syndrome: A case report

Ide, T., Ohno, M., Ito, T., Tsukamoto, K., Hirano, A., Sonoyama, H., Nakano, T., Furue, M. & Mashino, T., Jan 1 2019, In : Nishinihon Journal of Dermatology. 81, 3, p. 170-174 5 p.

Research output: Contribution to journalArticle

Stevens-Johnson Syndrome
Passive Immunization
Intravenous Immunoglobulins
Pulmonary Embolism
Tarsal Bones

Scratching counteracts il-13 signaling by upregulating the decoy receptor il-13rα2 in keratinocytes

Ulzii, D., Kido-Nakahara, M., Nakahara, T., Tsuji, G., Furue, K., Hashimoto-Hachiya, A. & Furue, M., Jul 1 2019, In : International journal of molecular sciences. 20, 13, 3324.

Research output: Contribution to journalArticle

Open Access
decoys
Interleukin-13
Keratinocytes
Interleukin-13 Receptors
dermatitis

Serum squamous cell carcinoma antigen (SCCA)-2 correlates with clinical severity of pediatric atopic dermatitis in Ishigaki cohort

Takeuchi, S., Furusyo, N., Ono, J., Azuma, Y., Takemura, M., Esaki, H., Yamamura, K., Mitamura, Y., Tsuji, G., Kiyomatsu-Oda, M., Hayashi, J., Izuhara, K. & Furue, M., Aug 2019, In : Journal of Dermatological Science. 95, 2, p. 70-75 6 p.

Research output: Contribution to journalArticle

Pediatrics
Atopic Dermatitis
Chemokine CCL17
Serum
Dermatitis
2018

A case of recalcitrant chronic urticaria successfully controlled by warfarin

Maehara, E., Mitoma, C., Takamatsu, H., Harada, K., Wada, N., Matsuda, T., Ishida, N., Imayama, S. & Urabe, K., Jan 1 2018, In : Nishinihon Journal of Dermatology. 80, 1, p. 15-19 5 p.

Research output: Contribution to journalArticle

Urticaria
Warfarin
Cyclosporine
Famotidine
Thrombin

A case of recurrent cutaneous Mycobacterium chelonae infection after treatment

Eto, A., Nakamura, M., Ito, S., Tanaka, M., Tsuji, G., Matsuda, T. & Furue, M., Jan 1 2018, In : Nishinihon Journal of Dermatology. 80, 6, p. 546-549 4 p.

Research output: Contribution to journalArticle

Mycobacterium chelonae
Mycobacterium Infections
Skin
Anti-Bacterial Agents
Infection

A case of unilateral Darier's disease

Isotani, T., Kimura, N., Shigyou, A., Kiryu, H. & Furue, M., Jan 1 2018, In : Nishinihon Journal of Dermatology. 80, 2, p. 113-116 4 p.

Research output: Contribution to journalArticle

Darier Disease
Etretinate
Skin
Cholecalciferol
Nails
1 Citation (Scopus)

Accumulation properties of polychlorinated biphenyl congeners in Yusho patients and prediction of their cytochrome P450-dependent metabolism by in silico analysis

Hirakawa, S., Miyawaki, T., Hori, T., Kajiwara, J., Katsuki, S., Hirano, M., Yoshinouchi, Y., Iwata, H., Mitoma, C. & Furue, M., Jun 1 2018, In : Environmental Science and Pollution Research. 25, 17, p. 16455-16463 9 p.

Research output: Contribution to journalArticle

Polychlorinated Biphenyls
Polychlorinated biphenyls
Metabolism
Computer Simulation
Cytochrome P-450 Enzyme System
12 Citations (Scopus)

An endogenous tryptophan photo-product, FICZ, is potentially involved in photo-aging by reducing TGF-β-regulated collagen homeostasis

Murai, M., Tsuji, G., Hashimoto-Hachiya, A., Kawakami, Y., Furue, M. & Mitoma, C., Jan 2018, In : Journal of Dermatological Science. 89, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Procollagen
Tryptophan
Collagen Type I
Aryl Hydrocarbon Receptors
3 Citations (Scopus)

Clinical condition and management of 114 mamushi (Gloydius blomhoffii) bites in a general hospital in Japan

Chiba, T., Koga, H., Kimura, N., Murata, M., Jinnai, S., Suenaga, A., Kohda, F. & Furue, M., Jan 1 2018, In : Internal Medicine. 57, 8, p. 1075-1080 6 p.

Research output: Contribution to journalArticle

Snake Bites
Bites and Stings
General Hospitals
Japan
Literature

Compound-specific isotopic and congener-specific analyses of polychlorinated biphenyl in the heat medium and rice oil of the Yusho incident

Miyawaki, T., Sugihara, M., Hirakawa, S., Hori, T., Kajiwara, J., Katsuki, S., Mitoma, C. & Furue, M., Jun 1 2018, In : Environmental Science and Pollution Research. 25, 17, p. 16464-16471 8 p.

Research output: Contribution to journalArticle

Polychlorinated Biphenyls
Polychlorinated biphenyls
heat transfer
PCB
Oils
3 Citations (Scopus)

Current state of yusho and prospects for therapeutic strategies

Mitoma, C., Uchi, H., Tsukimori, K., Todaka, T., Kajiwara, J., Shimose, T., Akahane, M., Imamura, T. & Furue, M., Jun 1 2018, In : Environmental Science and Pollution Research. 25, 17, p. 16472-16480 9 p.

Research output: Contribution to journalArticle

Dioxins
dioxin
Toxicity
Chelation
Bioactivity
6 Citations (Scopus)

Long-Term Health Effects of PCBs and Related Compounds: A Comparative Analysis of Patients Suffering from Yusho and the General Population

Akahane, M., Matsumoto, S., Kanagawa, Y., Mitoma, C., Uchi, H., Yoshimura, T., Furue, M. & Imamura, T., Feb 1 2018, In : Archives of Environmental Contamination and Toxicology. 74, 2, p. 203-217 15 p.

Research output: Contribution to journalArticle

Polychlorinated Biphenyls
Polychlorinated biphenyls
Health
Population
Aging of materials
3 Citations (Scopus)
Fibroblasts
Chemical activation
Interleukin-13
Skin
Oxidative stress
4 Citations (Scopus)

Perillaldehyde Inhibits AHR Signaling and Activates NRF2 Antioxidant Pathway in Human Keratinocytes

Fuyuno, Y., Uchi, H., Yasumatsu, M., Morino-Koga, S., Tanaka, Y., Mitoma, C. & Furue, M., Jan 1 2018, In : Oxidative medicine and cellular longevity. 2018, 1 p.

Research output: Contribution to journalArticle

Open Access
Aryl Hydrocarbon Receptors
Keratinocytes
Heme Oxygenase-1
Antioxidants
Reactive Oxygen Species

Recurrent varicella in a patient with systemic lupus erythematosus treated with immunosuppressants

Kimura, N., Urabe, K. & Furue, M., Jan 1 2018, In : Nishinihon Journal of Dermatology. 80, 4, p. 354-357 4 p.

Research output: Contribution to journalArticle

Human Herpesvirus 3
Chickenpox
Immunosuppressive Agents
Systemic Lupus Erythematosus
Simplexvirus
1 Citation (Scopus)

Sleep disorders among Yusho patients highly intoxicated with dioxin-related compounds: A 140-case series

Kondo, H., Tanio, K., Nagaura, Y., Nagayoshi, M., Mitoma, C., Furue, M. & Maeda, T., Oct 1 2018, In : Environmental Research. 166, p. 261-268 8 p.

Research output: Contribution to journalArticle

Restless Legs Syndrome
Dioxins
sleep
dioxin
Sleep
5 Citations (Scopus)

Tryptophan photo-product FICZ upregulates AHR/MEK/ERK-mediated MMP1 expression: Implications in anti-fibrotic phototherapy

Murai, M., Yamamura, K., Hashimoto-Hachiya, A., Tsuji, G., Furue, M. & Mitoma, C., Jul 2018, In : Journal of Dermatological Science. 91, 1, p. 97-103 7 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinases
Aryl Hydrocarbon Receptors
Phototherapy
Microtubule-Associated Proteins
Extracellular Signal-Regulated MAP Kinases
2017
8 Citations (Scopus)

6-Formylindolo[3,2-b]Carbazole Accelerates Skin Wound Healing via Activation of ERK, but Not Aryl Hydrocarbon Receptor

Morino-Koga, S., Uchi, H., Mitoma, C., Wu, Z., Kiyomatsu, M., Fuyuno, Y., Nagae, K., Yasumatsu, M., Suico, M. A., Kai, H. & Furue, M., Oct 2017, In : Journal of Investigative Dermatology. 137, 10, p. 2217-2226 10 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Wound Healing
Skin
Chemical activation
Keratinocytes

A case of angiosarcoma successfully treated with chemoradiation therapy

Nakaie, R., Mitoma, C., Takahara, M., Uchi, H. & Furue, M., Jan 1 2017, In : Nishinihon Journal of Dermatology. 79, 5, p. 482-486 5 p.

Research output: Contribution to journalArticle

docetaxel
Hemangiosarcoma
Neoplasms
Head
Paclitaxel

A case of cutaneous polyarteritis nodosa improved by drinking bidens pilosa tea as an alternative therapy

Nakagawa, R., Ichiki, T., Jinnai, S., Kohda, F., Mitoma, C. & Furue, M., Jan 1 2017, In : Nishinihon Journal of Dermatology. 79, 1, p. 24-27 4 p.

Research output: Contribution to journalArticle

Bidens
Polyarteritis Nodosa
Tea
Complementary Therapies
Drinking

A case of giant rhinophyma treated by surgical excision

Usagawa, Y., Mitoma, C., Wada, N., Uchi, H. & Furue, M., Jan 1 2017, In : Nishinihon Journal of Dermatology. 79, 4, p. 345-348 4 p.

Research output: Contribution to journalArticle

Rhinophyma
Nose
Sebaceous Glands
Neoplasms
Suppuration

A case of non-pigmented basal cell carcinoma on the dorsum of the nose

Maemura, H., Kimura, N., Takamatsu, H., Harada, K., Urabe, K. & Furue, M., Jan 1 2017, In : Nishinihon Journal of Dermatology. 79, 4, p. 371-375 5 p.

Research output: Contribution to journalArticle

Melanocytes
Basal Cell Carcinoma
Nose
MART-1 Antigen
Dermoscopy

A case of unilateral pustular pyoderma gangrenosum

Morioka, Y., Tsuji, G., Kawahara, S., Mizote, Y., Nakahara, T., Uchi, H. & Furue, M., Jan 1 2017, In : Nishinihon Journal of Dermatology. 79, 2, p. 136-139 4 p.

Research output: Contribution to journalArticle

Negative-Pressure Wound Therapy
Pyoderma Gangrenosum
Thigh
Ulcer
Sulfasalazine

A case report of vogt-koyanagi-harada disease with generalized vitiligo

Kimura, N., Maemura, H., Takamatsu, H., Harada, K., Urabe, K. & Furue, M., Jan 1 2017, In : Nishinihon Journal of Dermatology. 79, 3, p. 242-245 4 p.

Research output: Contribution to journalArticle

Uveomeningoencephalitic Syndrome
Vitiligo
Uveitis
Eyelids
Epidermis
3 Citations (Scopus)

Analysis of clinical symptoms and ABCC6 mutations in 76 Japanese patients with pseudoxanthoma elasticum

Iwanaga, A., Okubo, Y., Yozaki, M., Koike, Y., Kuwatsuka, Y., Tomimura, S., Yamamoto, Y., Tamura, H., Ikeda, S., Maemura, K., Tsuiki, E., Kitaoka, T., Endo, Y., Mishima, H., Yoshiura, K. I., Ogi, T., Tanizaki, H., Wataya-Kaneda, M., Hattori, T. & Utani, A., Jun 1 2017, In : Journal of Dermatology. 44, 6, p. 644-650 7 p.

Research output: Contribution to journalArticle

Pseudoxanthoma Elasticum
Mutation
Databases
Skin
Blood Vessels
24 Citations (Scopus)

Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis

Tsuji, G., Hashimoto-Hachiya, A., Kiyomatsu-Oda, M., Takemura, M., Ohno, F., Ito, T., Morino-Koga, S., Mitoma, C., Nakahara, T., Uchi, H. & Furue, M., Jul 13 2017, In : Cell death & disease. 8, 7, p. e2931

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Atopic Dermatitis
Keratinocytes
Up-Regulation
Skin
2 Citations (Scopus)

Calcification in dermal fibroblasts from a patient with GGCX syndrome accompanied by upregulation of osteogenic molecules

Okubo, Y., Masuyama, R., Iwanaga, A., Koike, Y., Kuwatsuka, Y., Ogi, T., Yamamoto, Y., Endo, Y., Tamura, H. & Utani, A., May 2017, In : PloS one. 12, 5, e0177375.

Research output: Contribution to journalArticle

calcification
Fibroblasts
fibroblasts
Up-Regulation
Skin

Dystrophic xanthomatization after radiotherapy for primary cutaneous anaplastic large cell lymphoma

Kitagawa, N., Mitoma, C., Yasukochi, Y., Sasaki, T., Uchi, H. & Furue, M., Jan 1 2017, In : Nishinihon Journal of Dermatology. 79, 2, p. 171-175 5 p.

Research output: Contribution to journalArticle

Primary Cutaneous Anaplastic Large Cell Lymphoma
Radiotherapy
Dermis
Ear
Neoplasms
11 Citations (Scopus)

Height is an indicator of vascular maintenance capacity in older men

Shimizu, Y., Sato, S., Koyamatsu, J., Yamanashi, H., Nagayoshi, M., Kadota, K. & Maeda, T., Oct 2017, In : Geriatrics and Gerontology International. 17, 10, p. 1729-1736 8 p.

Research output: Contribution to journalArticle

Blood Vessels
hypertension
Maintenance
Hypertension
Masked Hypertension
20 Citations (Scopus)

Inhibition of aryl hydrocarbon receptor signaling and induction of NRF2-mediated antioxidant activity by cinnamaldehyde in human keratinocytes

Uchi, H., Yasumatsu, M., Morino-Koga, S., Mitoma, C. & Furue, M., Jan 1 2017, In : Journal of Dermatological Science. 85, 1, p. 36-43 8 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Keratinocytes
Antioxidants
Chemical activation
Dioxins
20 Citations (Scopus)

Isolated ACTH deficiency probably induced by autoimmune-related mechanism evoked with nivolumab

Kitajima, K., Ashida, K., Wada, N., Suetsugu, R., Takeichi, Y., Sakamoto, S., Uchi, H., Matsushima, T., Shiratsuchi, M., Ohnaka, K., Furue, M. & Nomura, M., May 1 2017, In : Japanese journal of clinical oncology. 47, 5, p. 463-466 4 p., hyx018.

Research output: Contribution to journalArticle

Adrenocorticotropic Hormone
Hydrocortisone
Melanoma
Magnetic Resonance Imaging
Anterior Pituitary Hormones
7 Citations (Scopus)

Non-invasive evaluation of atopic dermatitis based on redox status using in vivo dynamic nuclear polarization magnetic resonance imaging

Eto, H., Tsuji, G., Chiba, T., Furue, M. & Hyodo, F., Feb 1 2017, In : Free Radical Biology and Medicine. 103, p. 209-215 7 p.

Research output: Contribution to journalArticle

Magnetic resonance
Atopic Dermatitis
Oxidation-Reduction
Skin
Magnetic Resonance Spectroscopy

Plantar fibromatosis accompanied with multiple keloids-Possible pathogenesis of fibromatosis-

Nakaie, R., Mitoma, C., Takahara, M., Uchi, H. & Furue, M., Jan 1 2017, In : Nishinihon Journal of Dermatology. 79, 4, p. 357-360 4 p.

Research output: Contribution to journalArticle

Keloid
Fibroma
Actins
Foot
Collagen
15 Citations (Scopus)

Platelets and circulating CD34-positive cells as an indicator of the activity of the vicious cycle between hypertension and endothelial dysfunction in elderly Japanese men

Shimizu, Y., Sato, S., Koyamatsu, J., Yamanashi, H., Nagayoshi, M., Kadota, K., Kawashiri, S. Y., Inoue, K., Nagata, Y. & Maeda, T., Apr 1 2017, In : Atherosclerosis. 259, p. 26-31 6 p.

Research output: Contribution to journalArticle

Activity Cycles
Blood Platelets
Hypertension
Cell Count
Platelet Count
1 Citation (Scopus)

Prevalence and clinical features of restless legs syndrome among Japanese pregnant women without gestational complications

Hatanaka, A., Eto, H., Kato, C., Yamaguchi, Y., Sakamoto, H. & Kondo, H., Apr 1 2017, In : Sleep and Biological Rhythms. 15, 2, p. 183-186 4 p.

Research output: Contribution to journalArticle

Restless Legs Syndrome
Pregnant Women
Third Pregnancy Trimester
Ferritins
Folic Acid
2016

A case of Basaloid Follicular Hamartoma

Usagawa, Y., Mitoma, C., Ito, T., Ito, S., Kiryu, H., Uchi, H. & Furue, M., Aug 1 2016, In : Fukuoka igaku zasshi = Hukuoka acta medica. 107, 8, p. 155-160 6 p.

Research output: Contribution to journalArticle

Hamartoma
Germ Cells
Neoplasms
Basal Cell Carcinoma
Follicular Cyst

A case of erythrodermic bullous pemphigoid

Morioka, Y., Tsuji, G., Kawahara, S., Mizote, Y., Nakahara, T., Uchi, H., Ishii, N. & Furue, M., Jan 1 2016, In : Nishinihon Journal of Dermatology. 78, 3, p. 248-251 4 p.

Research output: Contribution to journalArticle

Exfoliative Dermatitis
Bullous Pemphigoid
Drug Eruptions
Direct Fluorescent Antibody Technique
Eczema
9 Citations (Scopus)

Activation of the OVOL1-OVOL2 axis in the hair bulb and in pilomatricoma

Ito, T., Tsuji, G., Ohno, F., Uchi, H., Nakahara, T., Hashimoto-Hachiya, A., Yoshida, Y., Yamamoto, O., Oda, Y. & Furue, M., Apr 1 2016, In : American Journal of Pathology. 186, 4, p. 1036-1043 8 p.

Research output: Contribution to journalArticle

Pilomatrixoma
Hair
Keratinocytes
Cell Differentiation
Cell Proliferation
11 Citations (Scopus)

Alterations of hepatic metabolism in chronic kidney disease via D-box-binding protein aggravate the renal dysfunction

Hamamura, K., Matsunaga, N., Ikeda, E., Kondo, H., Ikeyama, H., Tokushige, K., Itcho, K., Furuichi, Y., Yoshida, Y., Matsuda, M., Yasuda, K., Doi, A., Yokota, Y., Amamoto, T., Aramaki, H., Irino, Y., Koyanagi, S. & Ohdo, S., Mar 4 2016, In : Journal of Biological Chemistry. 291, 10, p. 4913-4927 15 p.

Research output: Contribution to journalArticle

Vitamin A
Chronic Renal Insufficiency
Metabolism
Carrier Proteins
Kidney
1 Citation (Scopus)

Association between circulating CD34- positive cells and serum alkaline phosphatase in relation to body mass index for elderly Japanese men

Shimizu, Y., Sato, S., Koyamatsu, J., Yamanashi, H., Nagayoshi, M., Kadota, K., Tsuruda, K., Hayashida, N., Abiru, N., Yamasaki, H., Takamura, N. & Maeda, T., Jan 14 2016, In : Journal of physiological anthropology. 35, 1, 2.

Research output: Contribution to journalArticle

Phosphatases
Alkaline Phosphatase
Body Mass Index
Cells
Serum
3 Citations (Scopus)

Change in decay rates of dioxin-like compounds in Yusho patients

Matsumoto, S., Akahane, M., Kanagawa, Y., Kajiwara, J., Mitoma, C., Uchi, H., Furue, M. & Imamura, T., Sep 7 2016, In : Environmental Health: A Global Access Science Source. 15, 1, 95.

Research output: Contribution to journalArticle

Dioxins
Half-Life
Eating
Theoretical Models
Dioxins and Dioxin-like Compounds
16 Citations (Scopus)
Hemangiosarcoma
Japan
Head
Taxoids
Skin
3 Citations (Scopus)
Polychlorinated Biphenyls
Dioxins
Clinical Trials
Polychlorinated Dibenzodioxins
colestimide
11 Citations (Scopus)

Effects of dioxin-related compounds on bone mineral density in patients affected by the Yusho incident

Fukushi, J. I., Tokunaga, S., Nakashima, Y., Motomura, G., Mitoma, C., Uchi, H., Furue, M. & Iwamoto, Y., Feb 1 2016, In : Chemosphere. 145, p. 25-33 9 p.

Research output: Contribution to journalArticle

Dioxins
dioxin
Bone Density
Minerals
bone

Group G streptococcal necrotizing soft tissue infection

Maehara, E., Tsuji, G., Mizote, Y., Takeuchi, N. & Furue, M., Jan 1 2016, In : Nishinihon Journal of Dermatology. 78, 6, p. 644-649 6 p.

Research output: Contribution to journalArticle

Soft Tissue Infections
Subcutaneous Tissue
Leg
Muscles
Magnetic Resonance Imaging