Research Institute for Deseases of the Chest

Research output

Research output per year 1983 2004 2005 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2023

• 490 Article
• 41 Review article
• 8 Letter
• 4 Editorial
• 4 More
  • 3 Comment/debate
  • 1 Chapter

Research output per year

Research output per year

Search results

• 2021

  Emerging therapeutic targets for idiopathic pulmonary fibrosis: preclinical progress and therapeutic implications

  Yanagihara, T., Scallan, C., Ask, K. & Kolb, M. R. J., 2021, In: Expert Opinion on Therapeutic Targets. 25, 11, p. 939-948 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Fibrosing Alveolitis 100%
  • Drug 50%
  • Biological Marker 25%
  • Combination Therapy 25%
  • Disease Course 25%
  4 Citations (Scopus)
• 2020

  Current models of pulmonary fibrosis for future drug discovery efforts

  Yanagihara, T., Chong, S. G., Vierhout, M., Hirota, J. A., Ask, K. & Kolb, M., Aug 2 2020, In: Expert Opinion on Drug Discovery. 15, 8, p. 931-941 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Lung Fibrosis 100%
  • Fibrosing Alveolitis 40%
  • Drug Discovery 40%
  • Drug 20%
  • Animal 20%
  22 Citations (Scopus)

• Insights into pathogenesis and clinical implications in myositis-associated interstitial lung diseases

  Yanagihara, T. & Inoue, Y., Sept 1 2020, In: Current Opinion in Pulmonary Medicine. 26, 5, p. 507-517 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Myositis 100%
  • Interstitial Lung Disease 85%
  • Lung 85%
  • Pathogenesis 57%
  • Dermatomyositis 57%
  8 Citations (Scopus)
• 2019

  Trends in the prevalence of airflow limitation in a general Japanese population: Two serial cross-sectional surveys from the Hisayama Study

  Ogata, H., Hirakawa, Y., Matsumoto, K., Hata, J., Yoshida, D., Fukuyama, S., Inoue, H., Kitazono, T., Ninomiya, T. & Nakanishi, Y., Mar 1 2019, In: BMJ open. 9, 3, e023673.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Airflow 100%
  • Prevalence 53%
  • Smoking 30%
  • Age 15%
  • Ethinylestradiol Plus Megestrol Acetate 15%
  2 Citations (Scopus)

• What have we learned from basic science studies on idiopathic pulmonary fibrosis?

  Yanagihara, T., Sato, S., Upagupta, C. & Kolb, M., Sept 30 2019, In: European Respiratory Review. 28, 153, 190029.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Idiopathic Pulmonary Fibrosis 100%
  • Fibrosing Alveolitis 100%
  • Combination Therapy 33%
  • Pathogenesis 33%
  • Age 33%
  24 Citations (Scopus)
• 2018

  Anticancer drug treatment for advanced lung cancer with interstitial lung disease

  Otsubo, K., Okamoto, I., Hamada, N. & Nakanishi, Y., Jul 2018, In: Respiratory Investigation. 56, 4, p. 307-311 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Interstitial Lung Disease 100%
  • Lung Cancer 90%
  • Chemotherapy 60%
  • Patient 50%
  • Therapeutic Procedure 30%
  15 Citations (Scopus)

• Preclinical Toxicity Studies for Regenerative Medicine in Japan

  Shigeto, J., Ichiki, T., Nii, T., Konno, K., Nakanishi, Y. & Sugiyama, D., Nov 2018, In: Clinical Therapeutics. 40, 11, p. 1813-1822 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Toxicity 100%
  • Neoplasm 28%
  • Drug 28%
  • Carcinogenesis 14%
  • Animal 14%
  6 Citations (Scopus)
• 2016

  Biomimetic peptides for the treatment of cancer

  Mine, Y., Munir, H., Nakanishi, Y. & Sugiyama, D., Jan 1 2016, In: Anticancer research. 36, 7, p. 3565-3570 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Peptide 100%
  • Biomimetics 71%
  • Protein 71%
  • Molecule 57%
  • Cells 42%
  14 Citations (Scopus)
• 2015

  Implementation of modern therapy approaches and research for non-small cell lung cancer in Japan

  Nakanishi, Y., Feb 1 2015, In: Respirology. 20, 2, p. 199-208 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Lung Cancer 100%
  • Patient 66%
  • Therapeutic Procedure 66%
  • Combination Therapy 33%
  • Biological Marker 33%
  6 Citations (Scopus)
• 2014

  [Personalized medicine in non-small-cell carcinoma].

  Iwama, E., Takayama, K., Baba, E. & Nakanishi, Y., Jan 1 2014, In: Fukuoka igaku zasshi = Hukuoka acta medica. 105, 3, p. 57-66 10 p.

  Research output: Contribution to journal › Review article › peer-review
  1 Citation (Scopus)

• Current status and future perspectives of cooperative study groups for lung cancer in Japan

  Kawano, Y., Okamoto, I., Fukuda, H., Ohe, Y., Nakamura, S., Nakagawa, K., Hotta, K., Kiura, K., Takiguchi, Y., Saka, H., Okamoto, H., Takayama, K., Semba, H., Kobayashi, K., Kenmotsu, H., Tsuboi, M., Yamamoto, N., Nukiwa, T. & Nakanishi, Y., Nov 1 2014, In: Respiratory Investigation. 52, 6, p. 339-347 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Clinical Trial 100%
  • Lung Cancer 77%
  • Groups 66%
  • Diseases 11%
  • Ensure 11%
  3 Citations (Scopus)

• Development of anaplastic lymphoma kinase (ALK) inhibitors and molecular diagnosis in ALK rearrangement-positive lung cancer

  Iwama, E., Okamoto, I., Harada, T., Takayama, K. & Nakanishi, Y., Mar 5 2014, In: OncoTargets and Therapy. 7, p. 375-385 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Anaplastic Lymphoma Kinase 100%
  • Non Small Cell Lung Cancer 40%
  • Anaplastic Lymphoma Kinase Inhibitor 40%
  • Lung Cancer 20%
  • Clinical Trial 20%
  40 Citations (Scopus)

• Intrinsic and extrinsic regulation of mammalian hematopoiesis in the fetal liver

  Swain, A., Inoue, T., Tan, K. S., Nakanishi, Y. & Sugiyama, D., Sept 2014, In: Histology and histopathology. 29, 9, p. 1077-1082 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Hematopoiesis 100%
  • Liver 88%
  • Regulatory Mechanism 55%
  • Stromal Cell 22%
  • Endothelial Cell 22%
  15 Citations (Scopus)
• 2011

  [Roles of costimulatory molecules in bronchial asthma].

  Matsumoto, K. & Nakanishi, Y., Aug 2011, In: Fukuoka igaku zasshi = Hukuoka acta medica. 102, 8, p. 243-253 11 p.

  Research output: Contribution to journal › Review article › peer-review
• 2010

  Lung cancer risk and genetic polymorphisms in DNA repair pathways: A meta-analysis

  Kiyohara, C., Takayama, K. & Nakanishi, Y., 2010, In: Journal of Nucleic Acids. 2010, 701760.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • DNA Repair 100%
  • Nested Gene 50%
  • Association 50%
  • Sample 25%
  • thought 25%
  46 Citations (Scopus)
• 2007

  Lung cancer susceptibility: Are we on our way to identifying a high-risk group?

  Kiyohara, C., Yoshimasu, K., Takayama, K. & Nakanishi, Y., Dec 1 2007, In: Future Oncology. 3, 6, p. 617-627 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • DNA 100%
  • High Risk Population 75%
  • DNA Repair 50%
  • Lung Cancer 50%
  • Cancer Susceptibility 50%
  14 Citations (Scopus)

• Major drug-induced lung diseases: adverse effects of anti-neoplastic agents in general

  Nakanishi, Y., Harada, T. & Takayama, K., Jun 10 2007, In: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 96, 6, p. 1123-1128 6 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• Role of endogenous inhibitors of cytokine signaling in allergic asthma

  Inoue, H., Fukuyama, S., Matsumoto, K., Kubo, M. & Yoshimura, A., Jan 2007, In: Current Medicinal Chemistry. 14, 2, p. 181-189 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cytokine Signaling 100%
  • Allergic Asthma 100%
  • Signal Transduction 66%
  • Differentiation 66%
  • Protein Family 66%
  23 Citations (Scopus)

• The pathogenesis of COPD: Lessons learned from in vivo animal models

  Fujita, M. & Nakanishi, Y., Feb 2007, In: Medical Science Monitor. 13, 2, p. RA19-RA24

  Research output: Contribution to journal › Review article › peer-review

  • Chronic Obstructive Lung Disease 100%
  • Pathogenesis 40%
  • Chronic Inflammation 20%
  • Animal 10%
  • Matrix Metalloproteinase 10%
  30 Citations (Scopus)

• Two different functions of doxycycline which is both an antimicrobial agent and an immune modulator

  Fujita, M. & Nakanishi, Y., Oct 2007, In: Anti-Infective Agents in Medicinal Chemistry. 6, 4, p. 222-227 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Doxycycline 100%
  • Clinical Trial 30%
  • Antiinfective Agent 20%
  • Therapeutic Procedure 10%
  • Analysis 10%
  1 Citation (Scopus)
• 2006

  Association of genetic polymorphisms in the base excision repair pathway with lung cancer risk: A meta-analysis

  Kiyohara, C., Takayama, K. & Nakanishi, Y., Dec 2006, In: Lung Cancer. 54, 3, p. 267-283 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • DNA Repair 100%
  • Nested Gene 60%
  • Association 60%
  • DNA 40%
  • Smoking 40%
  161 Citations (Scopus)

• EPHX1 polymorphisms and the risk of lung cancer: A HuGE review

  Kiyohara, C., Yoshimasu, K., Takayama, K. & Nakanishi, Y., Jan 2006, In: Epidemiology. 17, 1, p. 89-99 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • EPHX1 100%
  • Genotyping 40%
  • Nested Gene 30%
  • Exon 30%
  • Lysozyme 20%
  77 Citations (Scopus)
• 2005

  Apoptosis signaling pathways in lung diseases.

  Kuwano, K., Yoshimi, M., Maeyama, T., Hamada, N., Yamada, M. & Nakanishi, Y., Jan 2005, In: Medicinal chemistry. 1, 1, p. 49-56 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Programmed Cell Death 100%
  • Apoptosis 87%
  • Silo-Filler's Disease 50%
  • Lung Disease 50%
  • Signal Transduction 25%
  24 Citations (Scopus)

• Clinical evaluation of pulmonary cryptococcosis: Including a case report of pulmonary cryptoccosis mimicking COP and a review of 17 cases

  Ouchi, H., Fujita, M., Minami, T., Inoshima, I. & Nakanishi, Y., 2005, In: Japanese Journal of Chest Diseases. 64, 2, p. 161-166 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Pulmonary Cryptococcosis 100%
  • Hospital 50%
  • Clinical Trial 25%
  • Examination 25%
  • Case Report 25%
  2 Citations (Scopus)

• Lymphocytes in bronchial asthma

  Matsumoto, K., Inoue, H. & Nakanishi, Y., Feb 2005, In: Respiration and Circulation. 53, 2, p. 167-175 9 p.

  Research output: Contribution to journal › Review article › peer-review

• NQO1, MPO, and the risk of lung cancer: A HuGE review

  Kiyohara, C., Yoshimasu, K., Takayama, K. & Nakanishi, Y., Sept 2005, In: Genetics in Medicine. 7, 7, p. 463-478 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • Lung Cancer 100%
  • Myeloperoxidase 71%
  • Nested Gene 42%
  • Genotyping 42%
  • Haplotype 28%
  37 Citations (Scopus)
• 2004

  ALI/ARDS and corticosteroids

  Fujita, M. & Nakanishi, Y., Aug 2004, In: Respiration and Circulation. 52, 8, p. 775-780 6 p.

  Research output: Contribution to journal › Review article › peer-review

• Cytokines and Lung Diseases

  Kuwano, K., Hagimoto, N., Inoue, H. & Nakanishi, Y., Mar 2004, In: Respiration and Circulation. 52, 3, p. 271-278 8 p.

  Research output: Contribution to journal › Review article › peer-review

• Does molecular targeted therapy change the treatment for lung cancer?

  Nakanishi, Y., Sept 2004, In: Fukuoka igaku zasshi = Hukuoka acta medica. 95, 9, p. 205-209 5 p.

  Research output: Contribution to journal › Review article › peer-review

• The role of apoptosis in pulmonary fibrosis

  Kuwano, K., Hagimoto, N. & Nakanishi, Y., Jul 2004, In: Histology and histopathology. 19, 3, p. 867-881 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Lung Fibrosis 100%
  • Apoptosis 75%
  • Injury 50%
  • Inflammation 25%
  • Animal 25%
  40 Citations (Scopus)
• 2003

  EBM and molecular biology from the perspective of lung cancer due to tobacco smoking

  Nakanishi, Y. & Takayama, K., Jun 10 2003, In: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 92, 6, p. 1089-1095 7 p.

  Research output: Contribution to journal › Review article › peer-review

• Refractory Asthma and Airway Hyperresponsiveness

  Komori, M., Inoue, H., Matsumoto, K., Fukuyama, S. & Nakanishi, Y., Dec 2003, In: Respiration and Circulation. 51, 12, p. 1203-1207 5 p.

  Research output: Contribution to journal › Review article › peer-review
• 2002

  Management of paraneoplastic syndrome in lung cancer

  Inoue, K. & Nakanishi, Y., May 2002, In: Nippon rinsho. Japanese journal of clinical medicine. 60 Suppl 5, p. 536-539 4 p.

  Research output: Contribution to journal › Review article › peer-review

• Molecular mechanism of lung carcinogenesis

  Nakanishi, Y. & Hara, N., May 2002, In: Nippon rinsho. Japanese journal of clinical medicine. 60 Suppl 5, p. 58-62 5 p.

  Research output: Contribution to journal › Review article › peer-review

• Why does smoking cause lung cancer?

  Nakanishi, Y., Jan 2002, In: Fukuoka igaku zasshi = Hukuoka acta medica. 93, 1, p. 6-10 5 p.

  Research output: Contribution to journal › Review article › peer-review
• 2001

  Lung cancer

  Hara, N. & Nakanishi, Y., Nov 2001, In: Nippon rinsho. Japanese journal of clinical medicine. 59 Suppl 7, p. 322-328 7 p.

  Research output: Contribution to journal › Review article › peer-review
  1 Citation (Scopus)
• 2000

  Epidemiology of lung cancer in Japan

  Hara, N., Nakanishi, Y. & Izumi, M., May 2000, In: Nippon rinsho. Japanese journal of clinical medicine. 58, 5, p. 1005-1011 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Case-Control Study 100%
  • Cancer Screening 100%
  • Lung Cancer 66%
  • Diseases 66%
  • Lung Cancer Screening 66%
  8 Citations (Scopus)

• Gene therapy for lung cancer treatment

  Takayama, K., Nakanishi, Y. & Hara, N., May 2000, In: Nippon rinsho. Japanese journal of clinical medicine. 58, 5, p. 1048-1052 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cancer Cell 100%
  • Gene Therapy 75%
  • Gene 50%
  • Cancer Therapy 50%
  • Antiangiogenic 50%

• Treatment of lung cancer--state of the art in 2000

  Nakanishi, Y., Inoue, K. & Hara, N., Jul 2000, In: Gan to kagaku ryoho. Cancer & chemotherapy. 27, 8, p. 1247-1252 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Chemotherapy 100%
  • Combination Therapy 83%
  • Survival 66%
  • Patient 50%
  • Therapeutic Procedure 50%
  1 Citation (Scopus)
• 1997

  Paraneoplastic syndrome

  Nakanishi, Y., Takayama, K. & Hara, N., Oct 1997, In: Gan to kagaku ryoho. Cancer & chemotherapy. 24 Suppl 3, p. 445-450 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Hyponatremia 100%
  • Paraneoplastic Syndrome 100%
  • Patient 66%
  • Combination Therapy 66%
  • Lung Cancer 66%
  2 Citations (Scopus)
• 1994

  Primary mediastinal germ cell tumors

  Hara, N. & Nakanishi, Y., 1994, In: Ryōikibetsu shōkōgun shirīzu. 4, p. 421-424 4 p.

  Research output: Contribution to journal › Review article › peer-review