Research Output 1983 2020

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2020
1 Citation (Scopus)

Japan Society of Clinical Oncology provisional clinical opinion for the diagnosis and use of immunotherapy in patients with deficient DNA mismatch repair tumors, cooperated by Japanese Society of Medical Oncology, First Edition

Mishima, S., Taniguchi, H., Akagi, K., Baba, E., Fujiwara, Y., Hirasawa, A., Ikeda, M., Maeda, O., Muro, K., Nishihara, H., Nishiyama, H., Takano, T., Tsuchihara, K., Yatabe, Y., Kodera, Y. & Yoshino, T., Feb 1 2020, In : International Journal of Clinical Oncology. 25, 2, p. 217-239 23 p.

Research output: Contribution to journalArticle

Open Access
DNA Repair-Deficiency Disorders
DNA Mismatch Repair
Medical Oncology
Immunotherapy
Japan

Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein–Barr virus-associated gastric cancer

Ohmura, H., Ito, M., Uchino, K., Okada, C., Tanishima, S., Yamada, Y., Momosaki, S., Komoda, M., Kuwayama, M., Yamaguchi, K., Okumura, Y., Nakano, M., Tsuchihashi, K., Isobe, T., Ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., Jan 1 2020, In : FEBS Open Bio. 10, 1, p. 147-157 11 p.

Research output: Contribution to journalArticle

Open Access
Methylation
Chemotherapy
DNA Methylation
Viruses
Drug Resistance
2019

aCGH Analysis of Predictive Biomarkers for Response to Bevacizumab plus Oxaliplatin- or Irinotecan-Based Chemotherapy in Patients with Metastatic Colorectal Cancer

Fujita, Y., Taguri, M., Yamazaki, K., Tsurutani, J., Sakai, K., Tsushima, T., Nagase, M., Tamagawa, H., Ueda, S., Tamura, T., Tsuji, Y., Murata, K., Taira, K., Denda, T., Moriwaki, T., Funai, S., Nakajima, T. E., Muro, K., Tsuji, A., Yoshida, M. & 11 others, Suyama, K., Kurimoto, T., Sugimoto, N., Baba, E., Seki, N., Sato, M., Shimura, T., Boku, N., Hyodo, I., Yamanaka, T. & Nishio, K., Mar 2019, In : Oncologist. 24, 3, p. 327-337 11 p.

Research output: Contribution to journalArticle

irinotecan
oxaliplatin
Comparative Genomic Hybridization
Colorectal Neoplasms
Biomarkers
1 Citation (Scopus)

Apparent Treatment-Resistant Hypertension and Cardiovascular Risk in Hemodialysis Patients: Ten-Year Outcomes of the Q-Cohort Study

Tanaka, S., Ninomiya, T., Hiyamuta, H., Taniguchi, M., Tokumoto, M., Masutani, K., Ooboshi, H., Nakano, T., Tsuruya, K. & Kitazono, T., Dec 1 2019, In : Scientific reports. 9, 1, 1043.

Research output: Contribution to journalArticle

Renal Dialysis
Cohort Studies
Hypertension
Confidence Intervals
Peripheral Arterial Disease

Association between Axial Length and Myopic Maculopathy: The Hisayama Study

Hashimoto, S., Yasuda, M., Fujiwara, K., Ueda, E., Hata, J., Hirakawa, Y., Ninomiya, T. & Sonoda, K. H., Oct 2019, In : Ophthalmology Retina. 3, 10, p. 867-873 7 p.

Research output: Contribution to journalArticle

Open Access
Odds Ratio
Confidence Intervals
Atrophy
Macular Degeneration
ROC Curve
2 Citations (Scopus)

Association between Genetic Risk and Development of Type 2 Diabetes in a General Japanese Population: The Hisayama Study

Inaishi, J., Hirakawa, Y., Horikoshi, M., Akiyama, M., Higashioka, M., Yoshinari, M., Hata, J., Mukai, N., Kamatani, Y., Momozawa, Y., Kubo, M. & Ninomiya, T., Jun 19 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 8, p. 3213-3222 10 p.

Research output: Contribution to journalArticle

Medical problems
Type 2 Diabetes Mellitus
Population
Hazards
Precision Medicine

Association between Serum β-Alanine and Risk of Dementia

Hata, J., Ohara, T., Katakura, Y., Shimizu, K., Yamashita, S., Yoshida, D., Honda, T., Hirakawa, Y., Shibata, M., Sakata, S., Kitazono, T., Kuhara, S. & Ninomiya, T., Sep 1 2019, In : American journal of epidemiology. 188, 9, p. 1637-1645 9 p.

Research output: Contribution to journalArticle

Alanine
Dementia
Anserine
Carnosine
Confidence Intervals
15 Citations (Scopus)

Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality: An Individual-Level Pooled Analysis of 30 Cohort Studies

Marklund, M., Wu, J. H. Y., Imamura, F., Del Gobbo, L. C., Fretts, A., De Goede, J., Shi, P., Tintle, N., Wennberg, M., Aslibekyan, S., Chen, T. A., De Oliveira Otto, M. C., Hirakawa, Y., Eriksen, H. H., Kröger, J., Laguzzi, F., Lankinen, M., Murphy, R. A., Prem, K., Samieri, C. & 67 others, Virtanen, J., Wood, A. C., Wong, K., Yang, W. S., Zhou, X., Baylin, A., Boer, J. M. A., Brouwer, I. A., Campos, H., Chaves, P. H. M., Chien, K. L., De Faire, U., Djoussé, L., Eiriksdottir, G., El-Abbadi, N., Forouhi, N. G., Michael Gaziano, J., Geleijnse, J. M., Gigante, B., Giles, G., Guallar, E., Gudnason, V., Harris, T., Harris, W. S., Helmer, C., Hellenius, M. L., Hodge, A., Hu, F. B., Jacques, P. F., Jansson, J. H., Kalsbeek, A., Khaw, K. T., Koh, W. P., Laakso, M., Leander, K., Lin, H. J., Lind, L., Luben, R., Luo, J., Mcknight, B., Mursu, J., Ninomiya, T., Overvad, K., Psaty, B. M., Rimm, E., Schulze, M. B., Siscovick, D., Skjelbo Nielsen, M., Smith, A. V., Steffen, B. T., Steffen, L., Sun, Q., Sundström, J., Tsai, M. Y., Tunstall-Pedoe, H., Uusitupa, M. I. J., Van Dam, R. M., Veenstra, J., Monique Verschuren, W. M., Wareham, N., Willett, W., Woodward, M., Yuan, J. M., Micha, R., Lemaitre, R. N., Mozaffarian, D. & Risérus, U., May 21 2019, In : Circulation. 139, 21, p. 2422-2436 15 p.

Research output: Contribution to journalArticle

Omega-6 Fatty Acids
Linoleic Acid
Cohort Studies
Cardiovascular Diseases
Biomarkers
10 Citations (Scopus)

Cardiovascular Risk Factors Associated with Venous Thromboembolism

Gregson, J., Kaptoge, S., Bolton, T., Pennells, L., Willeit, P., Burgess, S., Bell, S., Sweeting, M., Rimm, E. B., Kabrhel, C., Zöller, B., Assmann, G., Gudnason, V., Folsom, A. R., Arndt, V., Fletcher, A., Norman, P. E., Nordestgaard, B. G., Kitamura, A., Mahmoodi, B. K. & 54 others, Whincup, P. H., Knuiman, M., Salomaa, V., Meisinger, C., Koenig, W., Kavousi, M., Völzke, H., Cooper, J. A., Ninomiya, T., Casiglia, E., Rodriguez, B., Ben-Shlomo, Y., Després, J. P., Simons, L., Barrett-Connor, E., Björkelund, C., Notdurfter, M., Kromhout, D., Price, J., Sutherland, S. E., Sundström, J., Kauhanen, J., Gallacher, J., Beulens, J. W. J., Dankner, R., Cooper, C., Giampaoli, S., Deen, J. F., Gómez De La Cámara, A., Kuller, L. H., Rosengren, A., Svensson, P. J., Nagel, D., Crespo, C. J., Brenner, H., Albertorio-Diaz, J. R., Atkins, R., Brunner, E. J., Shipley, M., Njølstad, I., Lawlor, D. A., Van Der Schouw, Y. T., Selmer, R. M., Trevisan, M., Verschuren, W. M. M., Greenland, P., Wassertheil-Smoller, S., Lowe, G. D. O., Wood, A. M., Butterworth, A. S., Thompson, S. G., Danesh, J., Di Angelantonio, E. & Meade, T., Feb 2019, In : JAMA Cardiology. 4, 2, p. 163-173 11 p.

Research output: Contribution to journalArticle

Venous Thromboembolism
Adiposity
Pulmonary Embolism
Coronary Disease
Body Mass Index

Characteristics of the salivary microbiota in patients with various digestive tract cancers

Kageyama, S., Takeshita, T., Takeuchi, K., Asakawa, M., Matsumi, R., Furuta, M., Shibata, Y., Nagai, K., Ikebe, M., Morita, M., Masuda, M., Toh, Y., Kiyohara, Y., Ninomiya, T. & Yamashita, Y., Jan 1 2019, In : Frontiers in Microbiology. 10, 1780.

Research output: Contribution to journalArticle

Open Access
Microbiota
Gastrointestinal Tract
Neoplasms
Saliva
Pharyngeal Neoplasms
1 Citation (Scopus)

Dietary Sodium Reduction Reduces Albuminuria: A Cluster Randomized Trial

Jardine, M. J., Li, N., Ninomiya, T., Feng, X., Zhang, J., Shi, J., Zhang, Y., Zhang, R., Zhang, J., Hao, J., Perkovic, V., Heerspink, H. L., Wu, Y., Yan, L. L. & Neal, B., Jul 2019, In : Journal of Renal Nutrition. 29, 4, p. 276-284 9 p.

Research output: Contribution to journalArticle

Dietary Sodium
Albuminuria
Sodium
Albumins
Creatinine
17 Citations (Scopus)

Effect of SGLT2 inhibitors on cardiovascular, renal and safety outcomes in patients with type 2 diabetes mellitus and chronic kidney disease: A systematic review and meta-analysis

Toyama, T., Neuen, B. L., Jun, M., Ohkuma, T., Neal, B., Jardine, M. J., Heerspink, H. L., Wong, M. G., Ninomiya, T., Wada, T. & Perkovic, V., May 2019, In : Diabetes, Obesity and Metabolism. 21, 5, p. 1237-1250 14 p.

Research output: Contribution to journalArticle

Sodium-Glucose Transporter 2
Symporters
Chronic Renal Insufficiency
Type 2 Diabetes Mellitus
Meta-Analysis
10 Citations (Scopus)

Equalization of four cardiovascular risk algorithms after systematic recalibration: Individual-participant meta-analysis of 86 prospective studies

Pennells, L., Kaptoge, S., Wood, A., Sweeting, M., Zhao, X., White, I., Burgess, S., Willeit, P., Bolton, T., Moons, K. G. M., Van Der Schouw, Y. T., Selmer, R., Khaw, K. T., Gudnason, V., Assmann, G., Amouyel, P., Salomaa, V., Kivimaki, M., Nordestgaard, B. G., Blaha, M. J. & 200 others, Kuller, L. H., Brenner, H., Gillum, R. F., Meisinger, C., Ford, I., Knuiman, M. W., Rosengren, A., Lawlor, D. A., Völzke, H., Cooper, C., Marín Ibañez, A., Casiglia, E., Kauhanen, J., Cooper, J. A., Rodriguez, B., Sundström, J., Barrett-Connor, E., Dankner, R., Nietert, P. J., Davidson, K. W., Wallace, R. B., Blazer, D. G., Björkelund, C., Donfrancesco, C., Krumholz, H. M., Nissinen, A., Davis, B. R., Coady, S., Whincup, P. H., Jørgensen, T., Ducimetiere, P., Trevisan, M., Engström, G., Crespo, C. J., Meade, T. W., Visser, M., Kromhout, D., Kiechl, S., Daimon, M., Price, J. F., Gómez De La Cámara, A., Wouter Jukema, J., Lamarche, B., Onat, A., Simons, L. A., Kavousi, M., Ben-Shlomo, Y., Gallacher, J., Dekker, J. M., Arima, H., Shara, N., Tipping, R. W., Roussel, R., Brunner, E. J., Koenig, W., Sakurai, M., Pavlovic, J., Gansevoort, R. T., Nagel, D., Goldbourt, U., Barr, E. L. M., Palmieri, L., Njølstad, I., Sato, S., Monique Verschuren, W. M., Varghese, C. V., Graham, I., Onuma, O., Greenland, P., Woodward, M., Ezzati, M., Psaty, B. M., Sattar, N., Jackson, R., Ridker, P. M., Cook, N. R., D'Agostino, R. B., Thompson, S. G., Danesh, J., Di Angelantonio, E., Simpson, L. M., Pressel, S. L., Couper, D. J., Nambi, V., Matsushita, K., Folsom, A. R., Shaw, J. E., Magliano, D. J., Zimmet, P. Z., Wannamethee, S. G., Willeit, J., Santer, P., Egger, G., Casas, J. P., Amuzu, A., Tikhonoff, V., Sutherland, S. E., Cushman, M., Søgaard, A. J., Håheim, L. L., Ariansen, I., Tybjærg-Hansen, A., Jensen, G. B., Schnohr, P., Giampaoli, S., Vanuzzo, D., Panico, S., Balkau, B., Bonnet, F., Marre, M., De La Cámara, A. G., Rubio Herrera, M. A., Friedlander, Y., McCallum, J., McLachlan, S., Guralnik, J., Phillips, C. L., Wareham, N., Schöttker, B., Saum, K. U., Holleczek, B., Tolonen, H., Vartiainen, E., Jousilahti, P., Harald, K., Massaro, J. M., Pencina, M., Vasan, R., Kayama, T., Kato, T., Oizumi, T., Jespersen, J., Møller, L., Bladbjerg, E. M., Chetrit, A., Wilhelmsen, L., Lissner, L., Dennison, E., Kiyohara, Y., Ninomiya, T., Doi, Y., Nijpels, G., Stehouwer, C. D. A., Kazumasa, Y., Iso, H., Kurl, S., Tuomainen, T. P., Salonen, J. T., Deeg, D. J. H., Nilsson, P. M., Bo, H., Melander, O., De Boer, I. H., DeFilippis, A. P., Verschuren, W. M. M., Watt, G., Verschuren, W. M. M., Tverdal, A., Kirkland, S., Shimbo, D., Shaffer, J., Bakker, S. J. L., Van Der Harst, P., Hillege, H. L., Dallongeville, J., Schulte, H., Trompet, S., Smit, R. A. J., Stott, D. J., Després, J. P., Cantin, B., Dagenais, G. R., Laughlin, G., Wingard, D., Aspelund, T., Eiriksdottir, G., Gudmundsson, E. F., Ikram, A., Van Rooij, F. J. A., Franco, O. H., Rueda-Ochoa, O. L., Muka, T., Glisic, M., Tunstall-Pedoe, H., Howard, B. V., Ying, Z., Jolly, S., Davey-Smith, G., Can, G., Yüksel, H., Nakagawa, H., Morikawa, Y., Miura, K., Ingelsson, M., Giedraitis, V., Gaziano, J. M., Shipley, M., Arndt, V., Ibañez, A. M. & Geleijnse, J. M., Feb 14 2019, In : European heart journal. 40, 7, p. 621-631 11 p.

Research output: Contribution to journalArticle

Open Access
Meta-Analysis
Prospective Studies
Cardiovascular Diseases
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Health Services Needs and Demand
1 Citation (Scopus)

Estimation of nephron number in living humans by combining unenhanced computed tomography with biopsy-based stereology

Sasaki, T., Tsuboi, N., Okabayashi, Y., Haruhara, K., Kanzaki, G., Koike, K., Kobayashi, A., Yamamoto, I., Takahashi, S., Ninomiya, T., Shimizu, A., Rule, A. D., Bertram, J. F. & Yokoo, T., Dec 1 2019, In : Scientific reports. 9, 1, 14400.

Research output: Contribution to journalArticle

Open Access
Nephrons
Tomography
Biopsy
Kidney
Tissue Donors

Glucose Tolerance Levels and Circumpapillary Retinal Nerve Fiber Layer Thickness in a General Japanese Population: The Hisayama Study

Fujiwara, K., Yasuda, M., Hata, J., Hirakawa, Y., Hashimoto, S., Ueda, E., Iwase, A., Araie, M., Yoshitomi, T., Ninomiya, T. & Sonoda, K. H., Sep 2019, In : American journal of ophthalmology. 205, p. 140-146 7 p.

Research output: Contribution to journalArticle

Nerve Fibers
Glucose
Population
Prediabetic State
Glucose Intolerance
3 Citations (Scopus)

Having few remaining teeth is associated with a low nutrient intake and low serum albumin levels in middle-aged and older Japanese individuals: Findings from the NIPPON DATA2010

Nakamura, M., Ojima, T., Nagahata, T., Kondo, I., Ninomiya, T., Yoshita, K., Arai, Y., Ohkubo, T., Murakami, K., Nishi, N., Murakami, Y., Takashima, N., Okuda, N., Kadota, A., Miyagawa, N., Kondo, K., Okamura, T., Ueshima, H., Okayama, A. & Miura, K., Jan 5 2019, In : Environmental health and preventive medicine. 24, 1, 1.

Research output: Contribution to journalArticle

Serum Albumin
Tooth
Food
Social Class
Oral Health
Exercise
Population
Independent Living
Japan
Light

Long-term regular exercise and intraocular pressure: the Hisayama Study

Fujiwara, K., Yasuda, M., Hata, J., Yoshida, D., Kishimoto, H., Hashimoto, S., Yoshitomi, T., Ninomiya, T. & Sonoda, K. H., Nov 1 2019, In : Graefe's Archive for Clinical and Experimental Ophthalmology. 257, 11, p. 2461-2469 9 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Exercise
Linear Models
Blood Pressure
Waist Circumference
4 Citations (Scopus)

Moyamoya Disease Susceptibility Variant RNF213 p.R4810K Increases the Risk of Ischemic Stroke Attributable to Large-Artery Atherosclerosis

Okazaki, S., Morimoto, T., Kamatani, Y., Kamimura, T., Kobayashi, H., Harada, K., Tomita, T., Higashiyama, A., Takahashi, J. C., Nakagawara, J., Koga, M., Toyoda, K., Washida, K., Saito, S., Takahashi, A., Hirata, M., Matsuda, K., Mochizuki, H., Chong, M., Paré, G. & 9 others, O'Donnell, M., Ago, T., Hata, J., Ninomiya, T., Dichgans, M., Debette, S., Kubo, M., Koizumi, A. & Ihara, M., Jan 8 2019, In : Circulation. 139, 2, p. 295-298 4 p.

Research output: Contribution to journalArticle

RING Finger Domains
Moyamoya Disease
Disease Susceptibility
Genetic Predisposition to Disease
Atherosclerosis
Open Access
Brain Natriuretic Peptide
Dementia
Population
Serum
Alzheimer Disease
Open Access
Diabetes Mellitus
Insulin Resistance
Population
Homeostasis
Energy Intake
2 Citations (Scopus)

Periodontitis Is Associated with Chronic Obstructive Pulmonary Disease

Takeuchi, K., Matsumoto, K., Furuta, M., Fukuyama, S., Takeshita, T., Ogata, H., Suma, S., Shibata, Y., Shimazaki, Y., Hata, J., Ninomiya, T., Nakanishi, Y., Inoue, H. & Yamashita, Y., May 1 2019, In : Journal of Dental Research. 98, 5, p. 534-540 7 p.

Research output: Contribution to journalArticle

Periodontitis
Chronic Obstructive Pulmonary Disease
Vital Capacity
Forced Expiratory Volume
Confidence Intervals
2 Citations (Scopus)

Physical component quality of life reflects the impact of time and moderate chronic kidney disease, unlike SF-6D utility and mental component SF-36 quality of life: An AusDiab analysis

Wong, M. G., Ninomiya, T., Liyanage, T., Sukkar, L., Hirakawa, Y., Wang, Y., Wyld, M. L. R., Morton, R. L., Chadban, S., Howard, K. & Jardine, M. J., Jun 2019, In : Nephrology. 24, 6, p. 605-614 10 p.

Research output: Contribution to journalArticle

Glomerular Filtration Rate
Chronic Renal Insufficiency
Albuminuria
Quality of Life
Social Adjustment

Poor glycemic control and posterior circulation ischemic stroke

Kuroda, J., Matsuo, R., Yamaguchi, Y., Sato, N., Kamouchi, M., Hata, J., Wakisaka, Y., Ago, T. & Kitazono, T., Apr 1 2019, In : Neurology: Clinical Practice. 9, 2, p. 129-139 11 p.

Research output: Contribution to journalArticle

Stroke
Propensity Score
Hemoglobins
Glucose
Insulin Resistance

Poor glycemic control and posterior circulation ischemic stroke

Fukuoka Stroke Registry Investigators, Apr 1 2019, In : Neurology: Clinical Practice. 9, 2, p. 129-139 11 p.

Research output: Contribution to journalArticle

Stroke
Propensity Score
Hemoglobins
Glucose
Insulin Resistance
1 Citation (Scopus)

Possibility of lung cancer risk in indium-exposed workers: An 11-year multicenter cohort study

Nakano, M., Omae, K., Tanaka, A. & Hirata, M., May 2019, In : Journal of Occupational Health. 61, 3, p. 251-256 6 p.

Research output: Contribution to journalArticle

Open Access
Indium
Multicenter Studies
Lung Neoplasms
Cohort Studies
Tomography

Prevalence of adult epilepsy in a general Japanese population: The Hisayama study

Tanaka, A., Hata, J., Akamatsu, N., Mukai, N., Hirakawa, Y., Yoshida, D., Kishimoto, H., Ohara, T., Mizuno, T., Tsuji, S., Kitazono, T. & Ninomiya, T., Mar 2019, In : Epilepsia Open. 4, 1, p. 182-186 5 p.

Research output: Contribution to journalArticle

Open Access
Epilepsy
Population
Cerebrovascular Disorders
Confidence Intervals
Tonic-Clonic Epilepsy
Open Access
Resistin
Eicosapentaenoic Acid
Docosahexaenoic Acids
Arachidonic Acid
Serum

Reduced Estimated GFR and Cardiac Remodeling: A Population-Based Autopsy Study

Izumaru, K., Hata, J., Nakano, T., Nakashima, Y., Nagata, M., Fukuhara, M., Oda, Y., Kitazono, T. & Ninomiya, T., Sep 2019, In : American Journal of Kidney Diseases. 74, 3, p. 373-381 9 p.

Research output: Contribution to journalArticle

Open Access
Glomerular Filtration Rate
Autopsy
Population
Fibrosis
Cell Size

Serum elaidic acid concentration and risk of dementia: The Hisayama Study

Honda, T., Ohara, T., Shinohara, M., Hata, J., Toh, R., Yoshida, D., Shibata, M., Ishida, T., Hirakawa, Y., Irino, Y., Sakata, S., Uchida, K., Kitazono, T., Kanba, S., Hirata, K. I. & Ninomiya, T., Nov 26 2019, In : Neurology. 93, 22, p. e2053-e2064

Research output: Contribution to journalArticle

Dementia
Alzheimer Disease
Serum
Vascular Dementia
Trans Fatty Acids

Serum ethylamine levels as an indicator of l-theanine consumption and the risk of type 2 diabetes in a general Japanese population: The hisayama study

Ninomiya, T., Kanzaki, N., Hirakawa, Y., Yoshinari, M., Higashioka, M., Honda, T., Shibata, M., Sakata, S., Yoshida, D., Teramoto, T., Takemoto, S., Nishimoto, S., Hata, J. & Kitazono, T., Jan 1 2019, In : Diabetes care. 42, 7, p. 1234-1240 7 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Serum
Population
Eating
Independent Living
Open Access
Cardiovascular Diseases
Incidence
Serum
Population
Independent Living
3 Citations (Scopus)

Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study

Larsson, S. C., Traylor, M., Burgess, S., Boncoraglio, G. B., Jern, C., Michaëlsson, K., Markus, H. S., Malik, R., Chauhan, G., Sargurupremraj, M., Okada, Y., Mishra, A., Rutten-Jacobs, L., Giese, A. K., Van Der Laan, S. W., Gretarsdottir, S., Anderson, C. D., Chong, M., Adams, H. H. H., Ago, T. & 237 others, Almgren, P., Amouyel, P., Ay, H., Bartz, R. M., Benavente, O. R., Bevan, S., Brown, R. D., Butterworth, A. S., Carrera, C., Carty, C. L., Chasman, D. I., Chen, W. M., Cole, J. W., Correa, A., Cotlarciuc, I., Cruchaga, C., Danesh, J., De Bakker, P. I. W., Destefano, A. L., Hoed, M. D., Duan, Q., Engelter, S. T., Falcone, G. J., Gottesman, R. F., Grewal, R. P., Gudnason, V., Gustafsson, S., Haessler, J., Harris, T. B., Hassan, A., Havulinna, A. S., Heckbert, S. R., Holliday, E. G., Howard, G., Hsu, F. C., Hyacinth, H. I., Ikram, M. A., Ingelsson, E., Irvin, M. R., Jian, X., Jiménez-Conde, J., Johnson, J. A., Jukema, J. W., Kanai, M., Keene, K. L., Kissela, B. M., Kleindorfer, D. O., Kooperberg, C., Kubo, M., Lange, L. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. M., Lemmens, R., Leys, D., Lewis, C. M., Lin, W. Y., Lindgren, A. G., Lorentzen, E., Magnusson, P. K., Maguire, J., Manichaikul, A., McArdle, P. F., Meschia, J. F., Mitchell, B. D., Mosley, T. H., Nalls, M. A., Ninomiya, T., O'Donnell, M. J., Psaty, B. M., Pulit, S. L., Rannikmäe, K., Reiner, A. P., Rexrode, K. M., Rice, K., Rich, S. S., Ridker, P. M., Rost, N. S., Rothwell, P. M., Rotter, J. I., Rundek, T., Sacco, R. L., Sakaue, S., Sale, M. M., Salomaa, V., Sapkota, B. R., Schmidt, R., Schmidt, C. O., Schminke, U., Sharma, P., Slowik, A., Sudlow, C. L. M., Tanislav, C., Tatlisumak, T., Taylor, K. D., Thijs, V. N. S., Thorleifsson, G., Thorsteinsdottir, U., Tiedt, S., Trompet, S., Tzourio, C., Van Duijn, C. M., Walters, M., Wareham, N. J., Wassertheil-Smoller, S., Wilson, J. G., Wiggins, K. L., Yang, Q., Yusuf, S., Amin, N., Aparicio, H. S., Arnett, D. K., Attia, J., Beiser, A. S., Berr, C., Buring, J. E., Bustamante, M., Caso, V., Cheng, Y. C., Choi, S. H., Chowhan, A., Cullell, N., Dartigues, J. F., Delavaran, H., Delgado, P., Dörr, M., Engström, G., Ford, I., Gurpreet, W. S., Hamsten, A., Heitsch, L., Hozawa, A., Ibanez, L., Ilinca, A., Ingelsson, M., Iwasaki, M., Jackson, R. D., Jood, K., Jousilahti, P., Kaffashian, S., Kalra, L., Kamouchi, M., Kitazono, T., Kjartansson, O., Kloss, M., Koudstaal, P. J., Krupinski, J., Labovitz, D. L., Laurie, C. C., Levi, C. R., Li, L., Lind, L., Lindgren, C. M., Lioutas, V., Liu, Y. M., Lopez, O. L., Makoto, H., Martinez-Majander, N., Matsuda, K., Minegishi, N., Montaner, J., Morris, A. P., Muiño, E., Müller-Nurasyid, M., Norrving, B., Ogishima, S., Parati, E. A., Peddareddygari, L. R., Pedersen, N. L., Pera, J., Perola, M., Pezzini, A., Pileggi, S., Rabionet, R., Riba-Llena, I., Ribasés, M., Romero, J. R., Roquer, J., Rudd, A. G., Sarin, A. P., Sarju, R., Sarnowski, C., Sasaki, M., Satizabal, C. L., Satoh, M., Sattar, N., Sawada, N., Sibolt, G., Sigurdsson, Á., Smith, A., Sobue, K., Soriano-Tárraga, C., Stanne, T., Stine, O. C., Stott, D. J., Strauch, K., Takai, T., Tanaka, H., Tanno, K., Teumer, A., Tomppo, L., Torres-Aguila, N. P., Touze, E., Tsugane, S., Uitterlinden, A. G., Valdimarsson, E. M., Van Der Lee, S. J., Völzke, H., Wakai, K., Weir, D., Williams, S. R., Wolfe, C. D. A., Wong, Q., Xu, H., Yamaji, T., Sanghera, D. K., Melander, O., Strbian, D., Fernandez-Cadenas, I., Longstreth, W. T., Rolfs, A., Hata, J., Woo, D., Rosand, J., Pare, G., Hopewell, J. C., Saleheen, D., Stefansson, K., Worrall, B. B., Kittner, S. J., Seshadri, S., Fornage, M., Howson, J. M. M., Kamatani, Y., Debette, S. & Dichgans, M., Feb 26 2019, In : Neurology. 92, 9, p. E944-E950

Research output: Contribution to journalArticle

Open Access
Random Allocation
Magnesium
Stroke
Calcium
Serum
4 Citations (Scopus)

Serum Soluble Triggering Receptor Expressed on Myeloid Cells 2 as a Biomarker for Incident Dementia: The Hisayama Study

Ohara, T., Hata, J., Tanaka, M., Honda, T., Yamakage, H., Yoshida, D., Inoue, T., Hirakawa, Y., Kusakabe, T., Shibata, M., Teraoka, T., Kitazono, T., Kanba, S., Satoh-Asahara, N. & Ninomiya, T., Jan 2019, In : Annals of Neurology. 85, 1, p. 47-58 12 p.

Research output: Contribution to journalArticle

Myeloid Cells
Dementia
Biomarkers
Alzheimer Disease
Vascular Dementia
1 Citation (Scopus)

Steno-stiffness approach for cardiovascular disease risk assessment in primary prevention

Tomiyama, H., Ohkuma, T., Ninomiya, T., Mastumoto, C., Kario, K., Hoshide, S., Kita, Y., Inoguchi, T., Maeda, Y., Kohara, K., Tabara, Y., Nakamura, M., Ohkubo, T., Watada, H., Munakata, M., Ohishi, M., Ito, N., Nakamura, M., Shoji, T., Vlachopoulos, C. & 2 others, Aboyans, V. & Yamashina, A., Mar 1 2019, In : Hypertension. 73, 3, p. 508-513 6 p.

Research output: Contribution to journalArticle

Primary Prevention
Cardiovascular Diseases
Open Access
Tauopathies
Basal Ganglia
Microtubule-Associated Proteins
Alzheimer Disease
Parkinsonian Disorders

Trends in the prevalence of myopia and myopic maculopathy in a Japanese population: The hisayama study

Ueda, E., Yasuda, M., Fujiwara, K., Hashimoto, S., Ohno-Matsui, K., Hata, J., Ishibashi, T., Ninomiya, T. & Sonoda, K. H., Jul 2019, In : Investigative Ophthalmology and Visual Science. 60, 8, p. 2781-2786 6 p.

Research output: Contribution to journalArticle

Open Access
Myopia
Atrophy
Population
Refractive Errors
Photography
2 Citations (Scopus)
Prediabetic State
Type 2 Diabetes Mellitus
Body Mass Index
Glucose Tolerance Test
Obesity
1 Citation (Scopus)

World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions

Kaptoge, S., Pennells, L., De Bacquer, D., Cooney, M. T., Kavousi, M., Stevens, G., Riley, L. M., Savin, S., Khan, T., Altay, S., Amouyel, P., Assmann, G., Bell, S., Ben-Shlomo, Y., Berkman, L., Beulens, J. W., Björkelund, C., Blaha, M., Blazer, D. G., Bolton, T. & 81 others, Bonita Beaglehole, R., Brenner, H., Brunner, E. J., Casiglia, E., Chamnan, P., Choi, Y. H., Chowdry, R., Coady, S., Crespo, C. J., Cushman, M., Dagenais, G. R., D'Agostino, R. B., Daimon, M., Davidson, K. W., Engström, G., Ford, I., Gallacher, J., Gansevoort, R. T., Gaziano, T. A., Giampaoli, S., Grandits, G., Grimsgaard, S., Grobbee, D. E., Gudnason, V., Guo, Q., Tolonen, H., Humphries, S., Iso, H., Jukema, J. W., Kauhanen, J., Kengne, A. P., Khalili, D., Koenig, W., Kromhout, D., Krumholz, H., Lam, T. H., Laughlin, G., Marín Ibañez, A., Meade, T. W., Moons, K. G. M., Nietert, P. J., Ninomiya, T., Nordestgaard, B. G., O'Donnell, C., Palmieri, L., Patel, A., Perel, P., Price, J. F., Providencia, R., Ridker, P. M., Rodriguez, B., Rosengren, A., Roussel, R., Sakurai, M., Salomaa, V., Sato, S., Schöttker, B., Shara, N., Shaw, J. E., Shin, H. C., Simons, L. A., Sofianopoulou, E., Sundström, J., Völzke, H., Wallace, R. B., Wareham, N. J., Willeit, P., Wood, D., Wood, A., Zhao, D., Woodward, M., Danaei, G., Roth, G., Mendis, S., Onuma, O., Varghese, C., Ezzati, M., Graham, I., Jackson, R., Danesh, J. & Di Angelantonio, E., Oct 2019, In : The Lancet Global Health. 7, 10, p. e1332-e1345

Research output: Contribution to journalArticle

Open Access
Cardiovascular Diseases
Blood Pressure
Stroke
Myocardial Infarction
Cholesterol
2018
4 Citations (Scopus)
Independent Living
Vascular Dementia
Albuminuria
Alzheimer Disease
Glomerular Filtration Rate
9 Citations (Scopus)

Ankle-brachial index measured by oscillometry is predictive for cardiovascular disease and premature death in the Japanese population: An individual participant data meta-analysis

collaborative group for the Japan Brachial-Ankle pulse wave VELocity individual participant data meta-analysis of prospective studies to examine the significance of the Ankle-Brachial Index (J-BAVEL-ABI), Aug 2018, In : Atherosclerosis. 275, p. 141-148 8 p.

Research output: Contribution to journalArticle

Oscillometry
Ankle Brachial Index
Premature Mortality
Meta-Analysis
Cardiovascular Diseases
1 Citation (Scopus)
Myeloid Cells
Insulin Resistance
Serum
Population
Fats
5 Citations (Scopus)
Dementia
Sleep
Mortality
Hypnotics and Sedatives
Confidence Intervals
3 Citations (Scopus)
Eicosapentaenoic Acid
Arachidonic Acid
Depression
Serum
Population
10 Citations (Scopus)

Association of adipocyte enhancer-binding protein 1 with Alzheimer's disease pathology in human hippocampi

Shijo, M., Honda, H., Suzuki, S. O., Hamasaki, H., Hokama, M., Abolhassani, N., Nakabeppu, Y., Ninomiya, T., Kitazono, T. & Iwaki, T., Jan 2018, In : Brain Pathology. 28, 1, p. 58-71 14 p.

Research output: Contribution to journalArticle

Adipocytes
Hippocampus
Carrier Proteins
Pathology
Alzheimer Disease
1 Citation (Scopus)

Association of Embolic Sources With Cause-Specific Functional Outcomes Among Adults With Cryptogenic Stroke

Fukuoka Stroke Registry Investigators, Sep 7 2018, In : JAMA network open. 1, 5, p. e182953

Research output: Contribution to journalArticle

Open Access
Stroke
Paradoxical Embolism
Embolism
Registries
National Institutes of Health (U.S.)

Association of Embolic Sources With Cause-Specific Functional Outcomes Among Adults With Cryptogenic Stroke

Fukuoka Stroke Registry Investigators, Sep 7 2018, In : JAMA network open. 1, 5, p. e182953

Research output: Contribution to journalArticle

Stroke
Paradoxical Embolism
Embolism
Registries
National Institutes of Health (U.S.)
15 Citations (Scopus)

Association of extremely high levels of high-density lipoprotein cholesterol with cardiovascular mortality in a pooled analysis of 9 cohort studies including 43,407 individuals: The EPOCH–JAPAN study

Evidence for Cardiovascular Prevention from Observational Cohorts in Japan (EPOCH–JAPAN) Research Group, May 1 2018, In : Journal of Clinical Lipidology. 12, 3, p. 674-684.e5

Research output: Contribution to journalArticle

HDL Cholesterol
Cohort Studies
Mortality
Cardiovascular Diseases
Cause of Death
4 Citations (Scopus)

Clustering of risk factors and the risk of incident cardiovascular disease in Asian and Caucasian populations: Results from the Asia Pacific Cohort Studies Collaboration

Peters, S. A. E., Wang, X., Lam, T. H., Kim, H. C., Ho, S., Ninomiya, T., Knuiman, M., Vaartjes, I., Bots, M. L. & Woodward, M., Mar 1 2018, In : BMJ open. 8, 3, e019335.

Research output: Contribution to journalArticle

Cluster Analysis
Cohort Studies
Cardiovascular Diseases
Population
Blood Pressure

Comparison of the periodontal condition in Korean and Japanese adults: A cross-sectional study

Furuta, M., Takeuchi, K., Shimazaki, Y., Takeshita, T., Shibata, Y., Hata, J., Yoshida, D., Park, D. Y., Ninomiya, T. & Yamashita, Y., Nov 1 2018, In : BMJ open. 8, 11, e024332.

Research output: Contribution to journalArticle

Japan
Cross-Sectional Studies
Periodontal Diseases
Republic of Korea
Korea