If you made any changes in Pure these will be visible here soon.

Fingerprint Dive into the research topics where Atsushi Nonami is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Leukemia Medicine & Life Sciences
Acute Myeloid Leukemia Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Chemical activation Chemical Compounds
Therapeutics Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Lymphoma Medicine & Life Sciences
Protein-Tyrosine Kinases Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2003 2019

  • 1109 Citations
  • 18 h-Index
  • 31 Article
  • 2 Letter
  • 2 Review article
5 Citations (Scopus)

Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth

Oshima, T., Niwa, Y., Kuwata, K., Srivastava, A., Hyoda, T., Tsuchiya, Y., Kumagai, M., Tsuyuguchi, M., Tamaru, T., Sugiyama, A., Ono, N., Zolboot, N., Aikawa, Y., Oishi, S., Nonami, A., Arai, F., Hagihara, S., Yamaguchi, J., Tama, F., Kunisaki, Y. & 6 others, Yagita, K., Ikeda, M., Kinoshita, T., Kay, S. A., Itami, K. & Hirota, T., Jan 23 2019, In : Science Advances. 5, 1, eaau9060.

Research output: Contribution to journalArticle

Open Access
Circadian Rhythm
Circadian Clocks
Phosphotransferases
Growth
Neoplasms
17 Citations (Scopus)

Inhibition of USP10 induces degradation of oncogenic FLT3

Weisberg, E. L., Schauer, N. J., Yang, J., Lamberto, I., Doherty, L., Bhatt, S., Nonami, A., Meng, C., Letai, A., Wright, R., Tiv, H., Gokhale, P. C., Ritorto, M. S., De Cesare, V., Trost, M., Christodoulou, A., Christie, A., Weinstock, D. M., Adamia, S., Stone, R. & 8 others, Chauhan, D., Anderson, K. C., Seo, H. S., Dhe-Paganon, S., Sattler, M., Gray, N. S., Griffin, J. D. & Buhrlage, S. J., Dec 1 2017, In : Nature Chemical Biology. 13, 12, p. 1207-1215 9 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Phosphotransferases
Proteasome Endopeptidase Complex
Ubiquitin
Point Mutation
5 Citations (Scopus)

Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors

Tan, L., Rao, S., Mowafy, S., Du, G., Gray, N. S., Gurbani, D., Weisberg, E. L., Jones, D. S., Singer, W. D., Bernard, F. M., Jenney, A., Nonami, A., Griffin, J. D., Lauffenburger, D. A., Westover, K. D. & Sorger, P. K., Jan 1 2017, In : Bioorganic and Medicinal Chemistry. 25, 4, p. 1320-1328 9 p.

Research output: Contribution to journalArticle

Polypharmacology
Phosphotransferases
Neoplasms
Cells
Derivatives
20 Citations (Scopus)

Discovery of a BTK/MNK dual inhibitor for lymphoma and leukemia

Wu, H., Hu, C., Wang, A., Weisberg, E. L., Chen, Y., Yun, C. H., Wang, W., Liu, Y., Liu, X., Tian, B., Wang, J., Zhao, Z., Liang, Y., Li, B., Wang, L., Wang, B., Chen, C., Buhrlage, S. J., Qi, Z., Zou, F. & 14 others, Nonami, A., Li, Y., Fernandes, S. M., Adamia, S., Stone, R. M., Galinsky, I. A., Wang, X., Yang, G., Griffin, J. D., Brown, J. R., Eck, M. J., Liu, J., Gray, N. S. & Liu, Q., Jan 1 2016, In : Leukemia. 30, 1, p. 173-181 9 p.

Research output: Contribution to journalArticle

Lymphoma
Leukemia
Phosphotransferases
B-Lymphocytes
Acute Myeloid Leukemia
13 Citations (Scopus)

Ibrutinib selectively targets FLT3-ITD in mutant FLT3-positive AML

Wu, H., Hu, C., Wang, A., Weisberg, E. L., Wang, W., Chen, C., Zhao, Z., Yu, K., Liu, J., Wu, J., Nonami, A., Wang, L., Wang, B., Stone, R. M., Liu, S., Griffin, J. D., Liu, J. & Liu, Q., Mar 1 2016, In : Leukemia. 30, 3, p. 754-757 4 p.

Research output: Contribution to journalLetter

Leukemic Gene Expression Regulation
Heterocyclic Bridged Bicyclo Compounds
fms-Like Tyrosine Kinase 3
Benzamides
Pyrazoles