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Research Output 1995 2016

  • 3137 Citations
  • 21 h-Index
  • 21 Article
  • 4 Review article
  • 2 Comment/debate
  • 1 Chapter
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Article
2016
72 Citations (Scopus)

Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

Otera, H., Miyata, N., Kuge, O. & Mihara, K., Jan 1 2016, In : Journal of Cell Biology. 212, 5, p. 531-544 14 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Cytochromes c
Apoptosis
Cytoplasm
Phenotype
40 Citations (Scopus)

Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy

Yamashita, S. I., Jin, X., Furukawa, K., Hamasaki, M., Nezu, A., Otera, H., Saigusa, T., Yoshimori, T., Sakai, Y., Mihara, K. & Kanki, T., Jan 1 2016, In : Journal of Cell Biology. 215, 5, p. 649-665 17 p.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Mitochondria
Membranes
Autophagosomes
Quality Control
2014
70 Citations (Scopus)

Influenza a virus protein PB1-F2 translocates into mitochondria via Tom40 channels and impairs innate immunity

Yoshizumi, T., Ichinohe, T., Sasaki, O., Otera, H., Kawabata, S-I., Mihara, K. & Koshiba, T., Aug 20 2014, In : Nature communications. 5, 4713.

Research output: Contribution to journalArticle

influenza
Mitochondria
mitochondria
immunity
viruses
2013
52 Citations (Scopus)

Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology

Onoue, K., Jofuku, A., Ban-Ishihara, R., Ishihara, T., Maeda, M., Koshiba, T., Itoh, T., Fukuda, M., Otera, H., Oka, T., Takano, H., Mizushima, N., Mihara, K. & Ishihara, N., Jan 1 2013, In : Journal of Cell Science. 126, 1, p. 176-185 10 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
HeLa Cells
GTP Phosphohydrolases
Mitochondrial Proteins
Cell Extracts
2012
16 Citations (Scopus)

Pex5p imports folded tetrameric catalase by interaction with pex13p

Otera, H. & Fujiki, Y., Oct 1 2012, In : Traffic. 13, 10, p. 1364-1377 14 p.

Research output: Contribution to journalArticle

Catalase
Peroxisomes
Chloramphenicol O-Acetyltransferase
Protein Sorting Signals
Cytoplasm
2011
36 Citations (Scopus)

Discovery of the membrane receptor for mitochondrial fission GTPase Drp1

Otera, H. & Mihara, K., Jan 1 2011, In : Small GTPases. 2, 3, p. 1-6 6 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Guanosine
Yeast
Membranes
Yeasts
2010
502 Citations (Scopus)

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

Otera, H., Wang, C., Cleland, M. M., Setoguchi, K., Yokota, S., Youle, R. J. & Mihara, K., Dec 13 2010, In : Journal of Cell Biology. 191, 6, p. 1141-1158 18 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Dynamins
Guanosine
Mitochondrial Membranes
2009
543 Citations (Scopus)

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

Ishihara, N., Nomura, M., Jofuku, A., Kato, H., Suzuki, S. O., Masuda, K., Otera, H., Nakanishi, Y., Nonaka, I., Goto, Y. I., Taguchi, N., Morinaga, H., Maeda, M., Takayanagi, R., Yokota, S. & Mihara, K., Jul 6 2009, In : Nature Cell Biology. 11, 8, p. 958-966 9 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Synapses
Embryonic Development
Prosencephalon
Apoptosis
2007
69 Citations (Scopus)

A novel insertion pathway of mitochondrial outer membrane proteins with multiple transmembrane segments

Otera, H., Taira, Y., Horie, C., Suzuki, Y., Suzuki, H., Setoguchi, K., Kato, H., Oka, T. & Mihara, K., Dec 31 2007, In : Journal of Cell Biology. 179, 7, p. 1355-1363 9 p.

Research output: Contribution to journalArticle

Membrane Proteins
Membranes
Mitochondrial Membranes
GABA-A Receptors
Mitochondria
2006
119 Citations (Scopus)

Cytosolic factor- and TOM-independent import of C-tail-anchored mitochondrial outer membrane proteins

Setoguchi, K., Otera, H. & Mihara, K., Dec 13 2006, In : EMBO Journal. 25, 24, p. 5635-5647 13 p.

Research output: Contribution to journalArticle

Mitochondrial Membranes
Membrane Proteins
Protein C
Membranes
Digitonin
2005
27 Citations (Scopus)

A novel myc-target gene, mimitin, that is involved in cell proliferation of esophageal squamous cell carcinoma

Tsuneoka, M., Teye, K., Arima, N., Soejima, M., Otera, H., Ohashi, K., Koga, Y., Fujita, H., Shirouzu, K., Kimura, H. & Koda, Y., May 20 2005, In : Journal of Biological Chemistry. 280, 20, p. 19977-19985 9 p.

Research output: Contribution to journalArticle

myc Genes
Mitochondrial Proteins
Cell proliferation
Genes
Cell Proliferation
244 Citations (Scopus)

Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space

Otera, H., Ohsakaya, S., Nagaura, Z. I., Ishihara, N. & Mihara, K., Apr 6 2005, In : EMBO Journal. 24, 7, p. 1375-1386 12 p.

Research output: Contribution to journalArticle

Apoptosis Inducing Factor
Processing
Mitochondria
Apoptosis
Caspases
2002
151 Citations (Scopus)
Proteins
Amino Acids
Peroxisomes
Terminal Repeat Sequences
Alanine
2001
14 Citations (Scopus)

Biogenesis of nonspecific lipid transfer protein and sterol carrier protein x. Studies using peroxisome assembly-defective pex cell mutants

Otera, H., Nishimura, M., Setoguchi, K., Mori, T. & Fujiki, Y., Jan 26 2001, In : Journal of Biological Chemistry. 276, 4, p. 2858-2864 7 p.

Research output: Contribution to journalArticle

Peroxisomes
Cells
Cricetulus
Ovary
Molecular mass
2000
89 Citations (Scopus)
Mammals
Peroxisomes
Cricetulus
Ovary
Protein Isoforms
9 Citations (Scopus)

Peroxisome Biogenesis and Molecular Defects in Peroxisome Assembly Disorders

Fujiki, Y., Okumoto, K., Otera, H. & Tamura, S., Jan 1 2000, In : Cell Biochemistry and Biophysics. 32, p. 155-164 10 p.

Research output: Contribution to journalArticle

Peroxisomes
Membrane Proteins
Genes
Defects
Cricetulus
156 Citations (Scopus)

The mammalian peroxin Pex5pl, the longer isoform of the mobile peroxisome targeting signal (PTS) type 1 transporter, translocates the Pex7p·PTS2 protein complex into peroxisomes via its initial docking site, Pex14p

Otera, H., Harano, T., Honsho, M., Ghaedi, K., Mukai, S., Tanaka, A., Kawai, A., Shimizu, N. & Fujiki, Y., Jul 14 2000, In : Journal of Biological Chemistry. 275, 28, p. 21703-21714 12 p.

Research output: Contribution to journalArticle

Peroxisomes
Protein Isoforms
Proteins
Cytosol
Docks
1999
128 Citations (Scopus)

The peroxin Pex14p: cDNA cloning by functional complementation on a Chinese hamster ovary cell mutant, characterization, and functional analysis

Shimizu, N., Itoh, R., Hirono, Y., Otera, H., Ghaedi, K., Tateishi, K., Tamura, S., Okumoto, K., Harano, T., Mukai, S. & Fujiki, Y., Apr 30 1999, In : Journal of Biological Chemistry. 274, 18, p. 12593-12604 12 p.

Research output: Contribution to journalArticle

Functional analysis
Peroxisomes
Cloning
Cricetulus
Rats
18 Citations (Scopus)

Transmembrane topology of the peroxin, Pex2p, an essential component for the peroxisome assembly

Harano, T., Shimizu, N., Otera, H. & Fujiki, Y., 1999, In : Journal of Biochemistry. 125, 6, p. 1168-1174 7 p.

Research output: Contribution to journalArticle

Peroxisomes
Topology
Antibodies
Rats
Cytosol
1998
153 Citations (Scopus)

Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: Studies with PEX5-defective CHO cell mutants

Otera, H., Okumoto, K., Tateishi, K., Ikoma, Y., Matsuda, E., Nishimura, M., Tsukamoto, T., Osumi, T., Ohashi, K., Higuchi, O. & Fujiki, Y., Jan 1 1998, In : Molecular and cellular biology. 18, 1, p. 388-399 12 p.

Research output: Contribution to journalArticle

Peroxisomes
CHO Cells
Amino Acids
Protein Isoforms
Mutation
1995
161 Citations (Scopus)

Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs

Okano, I., Hiraoka, J., Otera, H., Nunoue, K., Ohashi, K., Iwashita, S., Hirai, M. & Mizuno, K., Dec 29 1995, In : Journal of Biological Chemistry. 270, 52, p. 31321-31330 10 p.

Research output: Contribution to journalArticle

Lim Kinases
Protein-Serine-Threonine Kinases
Protein Kinases
COS Cells
Ashes