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Research Output

  • 5262 Citations
  • 41 h-Index
  • 226 Article
  • 6 Review article
  • 5 Chapter
  • 4 Letter
2020

Cancer cell selective probe by mimicking EGCG

Kumazoe, M., Hiroi, S., Tanimoto, Y., Miyakawa, J., Yamanouchi, M., Suemasu, Y., Yoshitomi, R., Murata, M., Fujimura, Y., Takahashi, T., Tanaka, H. & Tachibana, H., May 14 2020, In : Biochemical and Biophysical Research Communications. 525, 4, p. 974-981 8 p.

Research output: Contribution to journalArticle

Procyanidin C1 Inhibits Melanoma Cell Growth by Activating 67-kDa Laminin Receptor Signaling

Bae, J., Kumazoe, M., Murata, K., Fujimura, Y. & Tachibana, H., Apr 1 2020, In : Molecular Nutrition and Food Research. 64, 7, 1900986.

Research output: Contribution to journalArticle

2019

Alkali-soluble pectin suppresses IgE production in human myeloma cell line in vitro

Iwamoto, A., Inoue, Y., Tachibana, H. & Kawahara, H., Apr 15 2019, In : Cytotechnology. 71, 2, p. 573-581 9 p.

Research output: Contribution to journalArticle

Diallyl disulfide potentiates anti-obesity effect of green tea in high-fat/high-sucrose diet-induced obesity

Bae, J., Kumazoe, M., Fujimura, Y. & Tachibana, H., Feb 1 2019, In : Journal of Nutritional Biochemistry. 64, p. 152-161 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Epigallocatechin-3-O-gallate induces acid sphingomyelinase activation through activation of phospholipase C

Bae, J., Kumazoe, M., Takeuchi, C., Hidaka, S., Fujimura, Y. & Tachibana, H., Nov 26 2019, In : Biochemical and Biophysical Research Communications. 520, 1, p. 186-191 6 p.

Research output: Contribution to journalArticle

Long-term dietary supplementation with the green tea cultivar Sunrouge prevents age-related cognitive decline in the senescence-accelerated mouse Prone8

Wasai, M., Nonaka, H., Murata, M., Kitamura, R., Sato, Y. & Tachibana, H., Jan 1 2019, In : Bioscience, Biotechnology and Biochemistry. 83, 2, p. 339-347 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

A harmonized immunoassay with liquid chromatography-mass spectrometry analysis in egg allergen determination

Nimata, M., Okada, H., Kurihara, K., Sugimoto, T., Honjoh, T., Kuroda, K., Yano, T., Tachibana, H. & Shoji, M., Jan 1 2018, In : Analytical and Bioanalytical Chemistry. 410, 2, p. 325-335 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A randomized, placebo-controlled study on the safety and efficacy of daily ingestion of green tea (Camellia sinensis l.) cv. “Yabukita” and “Sunrouge” on eyestrain and blood pressure in healthy adults

Maeda-Yamamoto, M., Nishimura, M., Kitaichi, N., Nesumi, A., Monobe, M., Nomura, S., Horie, Y., Tachibana, H. & Nishihira, J., May 2018, In : Nutrients. 10, 5, 569.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Inhibition of amyloid fibril formation in the variable domain of λ6 light chain mutant Wil caused by the interaction between its unfolded state and epigallocatechin-3-O-gallate

Abe, Y., Odawara, N., Aeimhirunkailas, N., Shibata, H., Fujisaki, N., Tachibana, H. & Ueda, T., Dec 2018, In : Biochimica et Biophysica Acta - General Subjects. 1862, 12, p. 2570-2578 9 p.

Research output: Contribution to journalArticle

Inhibition of amyloid fibril formation in the variable domain of λ6 light chain mutant Wil caused by the interaction between its unfolded state and epigallocatechin-3-O-gallate

Abe, Y., Odawara, N., Aeimhirunkailas, N., Shibata, H., Fujisaki, N., Tachibana, H. & Ueda, T., Dec 2018, In : Biochimica et Biophysica Acta - General Subjects. 1862, 12, p. 2570-2578 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Relationships among personality traits, metabolic syndrome, and metabolic syndrome scores: The Kakegawa cohort study

Ohseto, H., Ishikuro, M., Kikuya, M., Obara, T., Igarashi, Y., Takahashi, S., Kikuchi, D., Shigihara, M., Yamanaka, C., Miyashita, M., Mizuno, S., Nagai, M., Matsubara, H., Sato, Y., Metoki, H., Tachibana, H., Maeda-Yamamoto, M. & Kuriyama, S., Apr 2018, In : Journal of Psychosomatic Research. 107, p. 20-25 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Saturated fatty acid attenuates anti-obesity effect of green tea

Yamashita, S., Hirashima, A., Lin, I. C., Bae, J., Nakahara, K., Murata, M., Yamada, S., Kumazoe, M., Yoshitomi, R., Kadomatsu, M., Sato, Y., Nezu, A., Hikida, A., Fujino, K., Murata, K., Maeda-Yamamoto, M. & Tachibana, H., Dec 1 2018, In : Scientific reports. 8, 1, 10023.

Research output: Contribution to journalArticle

3 Citations (Scopus)

“Benifuuki” extract reduces serum levels of lectin-like oxidized low-density lipoprotein receptor-1 ligands containing apolipoprotein B: A double-blind placebo-controlled randomized trial

Miyawaki, M., Sano, H., Imbe, H., Fujisawa, R., Tanimoto, K., Terasaki, J., Maeda-Yamamoto, M., Tachibana, H., Hanafusa, T. & Imagawa, A., Jul 19 2018, In : Nutrients. 10, 7, 924.

Research output: Contribution to journalArticle

2017

A Chemometrics-driven Strategy for the Bioactivity Evaluation of Complex Multicomponent Systems and the Effective Selection of Bioactivity-predictive Chemical Combinations

Fujimura, Y., Kawano, C., Maeda-Murayama, A., Nakamura, A., Koike-Miki, A., Yukihira, D., Hayakawa, E., Ishii, T., Tachibana, H., Wariishi, H. & Miura, D., Dec 1 2017, In : Scientific reports. 7, 1, 2257.

Research output: Contribution to journalArticle

4 Citations (Scopus)
3 Citations (Scopus)

Delphinidin prevents muscle atrophy and upregulates MIR-23a expression

Murata, M., Nonaka, H., Komatsu, S., Goto, M., Morozumi, M., Yamada, S., Lin, I. C., Yamashita, S. & Tachibana, H., Jan 1 2017, In : Journal of Agricultural and Food Chemistry. 65, 1, p. 45-50 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Effect of Sunrouge on the postprandial blood glucose level - A randomized, double-blind, crossover-study

Wasai, M., Urata, N., Fujii, Y., Kawaoka, A., Tachibana, H., Fujiwara, S., Sakano, K., Hayashi, M. & Ebihara, S., Jan 1 2017, In : Japanese Pharmacology and Therapeutics. 45, 1, p. 105-111 7 p.

Research output: Contribution to journalArticle

FOXO3 is essential for CD44 expression in pancreatic cancer cells

Kumazoe, M., Takai, M., Bae, J., Hiroi, S., Huang, Y., Takamatsu, K., Won, Y., Yamashita, M., Hidaka, S., Yamashita, S., Yamada, S., Murata, M., Tsukamoto, S. & Tachibana, H., May 11 2017, In : Oncogene. 36, 19, p. 2643-2654 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Green tea cultivar ‘Benifuuki’ potentiates split vaccine-induced immunoglobulin A production

Won, Y. S., Kumazoe, M., Takamatsu, K., Shinoda, Y., Sonoda, S., Okada, K., Okamoto, T. & Tachibana, H., Jan 1 2017, In : Journal of Natural Medicines. 71, 1, p. 68-75 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Green tea polyphenol egcg upregulates tollip expression by suppressing ELF-1 expression

Kumazoe, M., Yamashita, M., Nakamura, Y., Takamatsu, K., Bae, J., Yamashita, S., Yamada, S., Onda, H., Nojiri, T., Kangawa, K. & Tachibana, H., Nov 1 2017, In : Journal of Immunology. 199, 9, p. 3261-3269 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Green tea polyphenol epigallocatechin-3-gallate suppresses toll-like receptor 4 expression via up-regulation of E3 ubiquitin-protein ligase RNF216

Kumazoe, M., Nakamura, Y., Yamashita, M., Suzuki, T., Takamatsu, K., Huang, Y., Bae, J., Yamashita, S., Murata, M., Yamada, S., Shinoda, Y., Yamaguchi, W., Toyoda, Y. & Tachibana, H., Mar 10 2017, In : Journal of Biological Chemistry. 292, 10, p. 4077-4088 12 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Hydrogen sulphide donors selectively potentiate a green tea polyphenol EGCG-induced apoptosis of multiple myeloma cells

Bae, J., Kumazoe, M., Yamashita, S. & Tachibana, H., Dec 1 2017, In : Scientific reports. 7, 1, 6665.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor

Huang, Y., Sumida, M., Kumazoe, M., Sugihara, K., Suemasu, Y., Yamada, S., Yamashita, S., Miyakawa, J., Takahashi, T., Tanaka, H., Fujimura, Y. & Tachibana, H., Jan 1 2017, In : Chemical Communications. 53, 12, p. 1941-1944 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

PDE3 inhibitor and EGCG combination treatment suppress cancer stem cell properties in pancreatic ductal adenocarcinoma

Kumazoe, M., Takai, M., Hiroi, S., Takeuchi, C., Yamanouchi, M., Nojiri, T., Onda, H., Bae, J., Huang, Y., Takamatsu, K., Yamashita, S., Yamada, S., Kangawa, K., Takahashi, T., Tanaka, H. & Tachibana, H., Dec 1 2017, In : Scientific reports. 7, 1, 1917.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Randomized controlled trial of the effects of consumption of ‘Yabukita’ or ‘Benifuuki’ encapsulated tea-powder on low-density lipoprotein cholesterol level and body weight

Igarashi, Y., Obara, T., Ishikuro, M., Matsubara, H., Shigihara, M., Metoki, H., Kikuya, M., Sameshima, Y., Tachibana, H., Maeda-Yamamoto, M. & Kuriyama, S., Jan 1 2017, In : Food and Nutrition Research. 61, 1334484.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

SphK1 inhibitor potentiates the anti-cancer effect of EGCG on leukaemia cells

Tsukamoto, S., Kumazoe, M., Huang, Y., Lesnick, C., Kay, N. E., Shanafelt, T. D. & Tachibana, H., Jul 2017, In : British Journal of Haematology. 178, 1, p. 155-158 4 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)

The FOXO3/PGC-1β signaling axis is essential for cancer stem cell properties of pancreatic ductal adenocarcinoma

Kumazoe, M., Takai, M., Hiroi, S., Takeuchi, C., Kadomatsu, M., Nojiri, T., Onda, H., Bae, J., Huang, Y., Takamatsu, K., Yamashita, S., Kangawa, K. & Tachibana, H., Jun 30 2017, In : Journal of Biological Chemistry. 292, 26, p. 10813-10823 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2016

6-Azido-6-deoxy-l-idose as a Hetero-Bifunctional Spacer for the Synthesis of Azido-Containing Chemical Probes

Hamagami, H., Kumazoe, M., Yamaguchi, Y., Fuse, S., Tachibana, H. & Tanaka, H., Jan 1 2016, In : Chemistry - A European Journal. 22, 36, p. 12884-12890 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

"Benifuuki" green tea, containing O-methylated EGCG, reduces serum low-density lipoprotein cholesterol and lectin-like oxidized low-density lipoprotein receptor-1 ligands containing apolipoprotein B: A double-blind, placebo-controlled randomized trial

Imbe, H., Sano, H., Miyawaki, M., Fujisawa, R., Miyasato, M., Nakatsuji, F., Haseda, F., Tanimoto, K., Terasaki, J., Maeda-Yamamoto, M., Tachibana, H. & Hanafusa, T., Aug 1 2016, In : Journal of Functional Foods. 25, p. 25-37 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Delphinidin prevents disuse muscle atrophy and reduces stress-related gene expression

Murata, M., Kosaka, R., Kurihara, K., Yamashita, S. & Tachibana, H., Jan 1 2016, In : Bioscience, Biotechnology and Biochemistry. 80, 8, p. 1636-1640 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Epigallocatechin-3-O-gallate up-regulates microRNA-let-7b expression by activating 67-kDa laminin receptor signaling in melanoma cells

Yamada, S., Tsukamoto, S., Huang, Y., Makio, A., Kumazoe, M., Yamashita, S. & Tachibana, H., Jan 12 2016, In : Scientific reports. 6, 19225.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Equol suppresses inflammatory response and bone erosion due to rheumatoid arthritis in mice

Lin, I. C., Yamashita, S., Murata, M., Kumazoe, M. & Tachibana, H., Jun 1 2016, In : Journal of Nutritional Biochemistry. 32, p. 101-106 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Green Tea Catechin Metabolites Exert Immunoregulatory Effects on CD4+ T Cell and Natural Killer Cell Activities

Kim, Y. H., Won, Y. S., Yang, X., Kumazoe, M., Yamashita, S., Hara, A., Takagaki, A., Goto, K., Nanjo, F. & Tachibana, H., May 11 2016, In : Journal of Agricultural and Food Chemistry. 64, 18, p. 3591-3597 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Involvement of polyphenol compounds in histamine release suppression by pomegranate vinegar

Miyazaki, Y., Kurata, Y., Koga, H., Yamaguchi, S., Tachibana, H. & Yamada, K., Jan 1 2016, In : Nippon Shokuhin Kagaku Kogaku Kaishi. 63, 2, p. 63-69 7 p.

Research output: Contribution to journalArticle

Oxidative deamination of serum albumins by (-)-epigallocatechin-3-O-gallate: A potential mechanism for the formation of innate antigens by antioxidants

Hatasa, Y., Chikazawa, M., Furuhashi, M., Nakashima, F., Shibata, T., Kondo, T., Akagawa, M., Hamagami, H., Tanaka, H., Tachibana, H. & Uchida, K., Apr 2016, In : PloS one. 11, 4, e0153002.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The combination of green tea extract and eriodictyol inhibited high-fat/high-sucrose diet-induced cholesterol upregulation is accompanied by suppression of cholesterol synthesis enzymes

Yamashita, M., Kumazoe, M., Nakamura, Y., Won, Y. S., Bae, J., Yamashita, S. & Tachibana, H., Jan 1 2016, In : Journal of Nutritional Science and Vitaminology. 62, 4, p. 249-256 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The Synthesis of trans-Flavan-3-ol Gallates by Regioselective Oxidative Etherification and Their Cytotoxicity Mediated by 67 LR

Shiraishi, N., Kumazoe, M., Fuse, S., Tachibana, H. & Tanaka, H., Jan 1 2016, In : Chemistry - A European Journal. 22, 37, p. 13050-13053 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

γ-Tocotrienol upregulates aryl hydrocarbon receptor expression and enhances the anticancer effect of baicalein

Yamashita, S., Baba, K., Makio, A., Kumazoe, M., Huang, Y., Lin, I. C., Bae, J., Murata, M., Yamada, S. & Tachibana, H., May 13 2016, In : Biochemical and Biophysical Research Communications. 473, 4, p. 801-807 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2015

1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose increases a population of T regulatory cells and inhibits IgE production in ovalbumin-sensitized mice

Kim, Y. H., Yang, X., Yamashita, S., Kumazoe, M., Huang, Y., Nakahara, K., Won, Y. S., Murata, M., Lin, I. C. & Tachibana, H., Jan 1 2015, In : International Immunopharmacology. 26, 1, p. 30-36 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Determination of vitamin C, S-methylmethionine and polyphenol contents, and functional activities of different parts of broccoli (Brassica Oleracea var. Italica)

Ueda, K., Tsukatani, T., Murayama, K., Kurata, Y., Takeda, E., Otsuka, T., Takai, M., Miyazaki, Y., Tachibana, H. & Yamada, K., Jan 1 2015, In : Nippon Shokuhin Kagaku Kogaku Kaishi. 62, 5, p. 242-249 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Green tea polyphenol epigallocatechin-O-gallate induces cell death by acid sphingomyelinase activation in chronic myeloid leukemia cells

Huang, Y., Kumazoe, M., Bae, J., Yamada, S., Takai, M., Hidaka, S., Yamashita, S., Kim, Y., Won, Y., Murata, M., Tsukamoto, S. & Tachibana, H., Sep 1 2015, In : Oncology reports. 34, 3, p. 1162-1168 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Metabolic Profiling-based Data-mining for an Effective Chemical Combination to Induce Apoptosis of Cancer Cells

Kumazoe, M., Fujimura, Y., Hidaka, S., Kim, Y., Murayama, K., Takai, M., Huang, Y., Yamashita, S., Murata, M., Miura, D., Wariishi, H., Maeda-Yamamoto, M. & Tachibana, H., Mar 2015, In : Scientific reports. 5, 9474.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Metabolomics of Green Tea

Fujimura, Y. & Tachibana, H., Oct 5 2015, Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods: Second Edition. Wiley-Blackwell, p. 397-406 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sphingosine kinase-1 protects multiple myeloma from apoptosis driven by cancer-specific inhibition of RTKs

Tsukamoto, S., Huang, Y., Kumazoe, M., Lesnick, C., Yamada, S., Ueda, N., Suzuki, T., Yamashita, S., Kim, Y. H., Fujimura, Y., Miura, D., Kay, N. E., Shanafelt, T. D. & Tachibana, H., Oct 1 2015, In : Molecular Cancer Therapeutics. 14, 10, p. 2303-2312 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Vardenafil, a clinically available phosphodiesterase inhibitor, potentiates the killing effect of EGCG on CLL cells

Kumazoe, M., Tsukamoto, S., Lesnick, C., Kay, N. E., Yamada, K., Shanafelt, T. D. & Tachibana, H., Feb 1 2015, In : British Journal of Haematology. 168, 4, p. 610-613 4 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2014

67-kDa laminin receptor-dependent Protein Phosphatase 2A (PP2A) activation elicits melanoma-specific antitumor activity overcoming drug resistance

Tsukamoto, S., Huang, Y., Umeda, D., Yamada, S., Yamashita, S., Kumazoe, M., Kim, Y., Murata, M., Yamada, K. & Tachibana, H., Nov 21 2014, In : Journal of Biological Chemistry. 289, 47, p. 32671-32681 11 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

IL-4 receptor α in non-lipid rafts is the target molecule of strictinin in inhibiting STAT6 activation

Kim, Y. H., Ninomiya, Y., Yamashita, S., Kumazoe, M., Huang, Y., Nakahara, K., Won, Y. S., Murata, M., Fujimura, Y., Yamada, K. & Tachibana, H., Jul 18 2014, In : Biochemical and Biophysical Research Communications. 450, 1, p. 824-830 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

In situ label-free visualization of orally dosed strictinin within mouse kidney by MALDI-MS imaging

Kim, Y. H., Fujimura, Y., Sasaki, M., Yang, X., Yukihira, D., Miura, D., Unno, Y., Ogata, K., Nakajima, H., Yamashita, S., Nakahara, K., Murata, M., Lin, I. C., Wariishi, H., Yamada, K. & Tachibana, H., Sep 24 2014, In : Journal of Agricultural and Food Chemistry. 62, 38, p. 9279-9285 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
7 Citations (Scopus)