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Research Output 1998 2019

2019

Nuclear co-expression of p21 and p27 induced effective cell-cycle arrest in T24 cells treated with BCG

Watanabe, S., Yamaguchi, S., Fujii, N., Eguchi, N., Katsuta, H., Sugishima, S., Iwasaka, T. & Kaku, T., Feb 15 2019, In : Cytotechnology. 71, 1, p. 219-229 11 p.

Research output: Contribution to journalArticle

Bacilli
Cell Cycle Checkpoints
Bacillus
Cells
Confocal Microscopy
2016
9 Citations (Scopus)

Adjusting the 17b-etradiol-to-androgen ratio ameliorates diabetic nephropathy

Inada, A., Inada, O., Fujii, N. L., Nagafuchi, S., Katsuta, H., Yasunami, Y., Matsubara, T., Arai, H., Fukatsu, A. & Nabeshima, Y. I., Jan 1 2016, In : Journal of the American Society of Nephrology. 27, 10, p. 3035-3050 16 p.

Research output: Contribution to journalArticle

Diabetic Nephropathies
Androgens
Transgenic Mice
Albuminuria
Hyperglycemia
2015
21 Citations (Scopus)

Reduced Tyk2 gene expression in β-cells due to natural mutation determines susceptibility to virus-induced diabetes

Izumi, K., Mine, K., Inoue, Y., Teshima, M., Ogawa, S., Kai, Y., Kurafuji, T., Hirakawa, K., Miyakawa, D., Ikeda, H., Inada, A., Hara, M., Yamada, H., Akashi, K., Niho, Y., Ina, K., Kobayashi, T., Yoshikai, Y., Anzai, K., Yamashita, T. & 6 others, Minagawa, H., Fujimoto, S., Kurisaki, H., Shimoda, K., Katsuta, H. & Nagafuchi, S., Apr 13 2015, In : Nature communications. 6, 6748.

Research output: Contribution to journalArticle

TYK2 Kinase
gene expression
tyrosine
viruses
Medical problems
15 Citations (Scopus)

TYK2 Promoter Variant and Diabetes Mellitus in the Japanese

Nagafuchi, S., Kamada-Hibio, Y., Hirakawa, K., Tsutsu, N., Minami, M., Okada, A., Kai, K., Teshima, M., Moroishi, A., Murakami, Y., Umeno, Y., Yokogawa, Y., Kogawa, K., Izumi, K., Anzai, K., Iwakiri, R., Hamaguchi, K., Sasaki, N., Nohara, S., Yoshida, E. & 16 others, Harada, M., Akashi, K., Yanase, T., Ono, J., Okeda, T., Fujimoto, R., Ihara, K., Hara, T., Kikuchi, Y., Iwase, M., Kitazono, T., Kojima, F., Kono, S., Kurisaki, H., Kondo, S. & Katsuta, H., Jul 1 2015, In : EBioMedicine. 2, 7, p. 744-749 6 p.

Research output: Contribution to journalArticle

Medical problems
Type 1 Diabetes Mellitus
Diabetes Mellitus
Type 2 Diabetes Mellitus
Genes
2014
16 Citations (Scopus)

Birth and death of human β-cells in pancreases from cadaver donors, autopsies, surgical specimens, and islets transplanted into mice

Caballero, F., Siniakowicz, K., Jennifer-Hollister-Lock, Duran, L., Katsuta, H., Yamada, T., Lei, J., Deng, S., Westermark, G. T., Markmann, J., Bonner-Weir, S. & Weir, G. C., Feb 1 2014, In : Cell Transplantation. 23, 2, p. 139-151 13 p.

Research output: Contribution to journalArticle

Cadaver
Pancreas
Autopsy
Cell Death
Tissue Donors
2013
3 Citations (Scopus)

Encephalomyocarditis virus

Nagafuchi, S., Kurisaki, H. & Katsuta, H., Mar 1 2013, Diabetes and Viruses. Springer New York, Vol. 9781461440512. p. 37-48 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Encephalomyocarditis virus
Viruses
Cercopithecine Herpesvirus 1
Autoimmunity
Type 1 Diabetes Mellitus

Errata to Liver-derived systemic factors drive β cell hyperplasia in insulin-resistant states [Cell Reports, 3 (2013) 401-410]

El Ouaamari, A., Kawamori, D., Dirice, E., Liew, C. W., Shadrach, J. L., Hu, J., Katsuta, H., Hollister-Lock, J., Qian, W. J., Wagers, A. J. & Kulkarni, R. N., Dec 24 2013, In : Cell Reports. 3, 3, 1 p.

Research output: Contribution to journalComment/debate

Liver
Insulin
93 Citations (Scopus)

Liver-Derived Systemic Factors Drive β Cell Hyperplasia in Insulin-Resistant States

El Ouaamari, A., Kawamori, D., Dirice, E., Liew, C. W., Shadrach, J. L., Hu, J., Katsuta, H., Hollister-Lock, J., Qian, W. J., Wagers, A. J. & Kulkarni, R. N., Feb 1 2013, In : Cell Reports. 3, 2, p. 401-410 10 p.

Research output: Contribution to journalArticle

Liver
Hyperplasia
Insulin
Insulin Receptor
Cell proliferation
11 Citations (Scopus)

Regulation of human autoimmune regulator (AIRE) gene translation by miR-220b

Matsuo, T., Noguchi, Y., Shindo, M., Morita, Y., Oda, Y., Yoshida, E., Hamada, H., Harada, M., Shiokawa, Y., Nishida, T., Tominaga, R., Kikushige, Y., Akashi, K., Kudoh, J., Shimizu, N., Tanaka, Y., Umemura, T., Taniguchi, T., Yoshimura, A., Kobayashi, T. & 4 others, Mitsuyama, M., Kurisaki, H., Katsuta, H. & Nagafuchi, S., Nov 1 2013, In : Gene. 530, 1, p. 19-25 7 p.

Research output: Contribution to journalArticle

Regulator Genes
3' Untranslated Regions
Autoimmune Polyendocrinopathies
Proteins
Mutation
2012
26 Citations (Scopus)

Subpopulations of GFP-marked mouse pancreatic β-cells differ in size, granularity, and insulin secretion

Katsuta, H., Aguayo-Mazzucato, C., Katsuta, R., Akashi, T., Hollister-Lock, J., Sharma, A. J., Bonner-Weir, S. & Weir, G. C., Nov 1 2012, In : Endocrinology. 153, 11, p. 5180-5187 8 p.

Research output: Contribution to journalArticle

Green Fluorescent Proteins
Insulin
Population
Transgenic Mice
Flow Cytometry
2010
27 Citations (Scopus)

Protective unfolded protein response in human pancreatic beta cells transplanted into mice

Kennedy, J., Katsuta, H., Jung, M. H., Marselli, L., Goldfine, A. B., Balis, U. J., Sgroi, D., Bonner-Weir, S. & Weir, G. C., Aug 12 2010, In : PloS one. 5, 6, e11211.

Research output: Contribution to journalArticle

unfolded protein response
Unfolded Protein Response
islets of Langerhans
Insulin-Secreting Cells
Laser Capture Microdissection
3 Citations (Scopus)

Rituximab, B-lymphocyte depletion, and beta-cell function

Nagafuchi, S., Katsuta, H. & Anzai, K., Feb 25 2010, In : New England Journal of Medicine. 362, 8, 1 p.

Research output: Contribution to journalLetter

Lymphocyte Depletion
Insulin-Secreting Cells
Immunologic Factors
Type 1 Diabetes Mellitus
B-Lymphocytes
42 Citations (Scopus)

Single pancreatic beta cells co-express multiple islet hormone genes in mice

Katsuta, H., Akashi, T., Katsuta, R., Nagaya, M., Kim, D., Arinobu, Y., Hara, M., Bonner-Weir, S., Sharma, A. J., Akashi, K. & Weir, G. C., Jan 1 2010, In : Diabetologia. 53, 1, p. 128-138 11 p.

Research output: Contribution to journalArticle

Insulin-Secreting Cells
Hormones
Green Fluorescent Proteins
Genes
Insulin
2009
52 Citations (Scopus)

Adult mouse intrahepatic biliary epithelial cells induced in vitro to become insulin-producing cells

Nagaya, M., Katsuta, H., Kaneto, H., Bonner-Weir, S. & Weir, G. C., Aug 4 2009, In : Journal of Endocrinology. 201, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

Epithelial Cells
Insulin
Homeobox Genes
Duodenum
Pancreas
16 Citations (Scopus)

Differentiation of COPAS-sorted non-endocrine pancreatic cells into insulin-positive cells in the mouse

Kikugawa, R., Katsuta, H., Akashi, T., Yatoh, S., Weir, G. C., Sharma, A. & Bonner-Weir, S., Apr 1 2009, In : Diabetologia. 52, 4, p. 645-652 8 p.

Research output: Contribution to journalArticle

Insulin
Stem Cells
Pancreas
Green Fluorescent Proteins
Real-Time Polymerase Chain Reaction
66 Citations (Scopus)

Towards better understanding of the contributions of overwork and glucotoxicity to the β-cell inadequacy of type 2 diabetes

Weir, G. C., Marselli, L., Marchetti, P., Katsuta, H., Jung, M. H. & Bonner-Weir, S., Jan 1 2009, In : Diabetes, Obesity and Metabolism. 11, SUPPL. 4, p. 82-90 9 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Phenotype
Laser Capture Microdissection
Frozen Sections
Hyperglycemia
2008
2 Citations (Scopus)

Adverse effects of obesity on β-cell function in Japanese subjects with normal glucose tolerance

Akehi, Y., Anzai, K., Katsuta, H., Yoshida, R., Ohkubo, K., Yamashita, T., Kawashima, H. & Ono, J., Sep 1 2008, In : Obesity Research and Clinical Practice. 2, 3, p. 195-202 8 p.

Research output: Contribution to journalArticle

Insulin Resistance
Obesity
Glucose
Homeostasis
Area Under Curve
307 Citations (Scopus)

Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth

Inada, A., Nienaber, C., Katsuta, H., Fujitani, Y., Levine, J., Morita, R., Sharma, A. & Bonner-Weir, S., Dec 16 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 50, p. 19915-19919 5 p.

Research output: Contribution to journalArticle

Carbonic Anhydrase II
Exocrine Pancreas
Islets of Langerhans
Stem Cells
Parturition
7 Citations (Scopus)

The significance of T cells, B cells, antibodies and macrophages against encephalomyocarditis (EMC)-D virus-induced diabetes in mice

Kounoue, E., Izumi, K. I., Ogawa, S., Kondo, S., Katsuta, H., Akashi, T., Niho, Y., Harada, M., Tamiya, S., Kurisaki, H. & Nagafuchi, S., Jul 1 2008, In : Archives of Virology. 153, 7, p. 1223-1231 9 p.

Research output: Contribution to journalArticle

Encephalomyocarditis virus
B-Lymphocytes
Macrophages
T-Lymphocytes
Antibodies
2007

Patients with dilated cardiomyopathy possess insulin resistance independently of cardiac dysfunction or serum tumor necrosis factor-α

Sakai, Y., Maruyama, T., Katsuta, H., Kogawa, K., Akashi, T., Izumi, K. I., Tominaga, H., Kono, S., Nagafuchi, S. & Harada, M., Feb 1 2007, In : International heart journal. 47, 6, p. 877-887 11 p.

Research output: Contribution to journalArticle

Dilated Cardiomyopathy
Insulin Resistance
Tumor Necrosis Factor-alpha
Serum
Heart Valve Diseases
2006
17 Citations (Scopus)

Autoimmune regulator (AIRE) gene is expressed in human activated CD4 + T-cells and regulated by mitogen-activated protein kinase pathway

Nagafuchi, S., Katsuta, H., Koyanagi-Katsuta, R., Yamasaki, S., Inoue, Y., Shimoda, K., Ikeda, Y., Shindo, M., Yoshida, E., Matsuo, T., Ohno, Y., Kogawa, K., Anzai, K., Kurisaki, H., Kudoh, J., Harada, M. & Shimizu, N., Jan 1 2006, In : MICROBIOLOGY and IMMUNOLOGY. 50, 12, p. 979-987 9 p.

Research output: Contribution to journalArticle

Regulator Genes
Mitogen-Activated Protein Kinases
Interleukin-2
T-Lymphocytes
p38 Mitogen-Activated Protein Kinases
2005

A case of metabolic syndrome with coronary artery disease advanced over 13 years. Case report

Tanigawa, T., Hayashida, A., Kamou, M., Kohno-Yoshida, E., Katsuta, H., Kaji, Y., Nagafuchi, S. & Harada, M., Jan 1 2005, In : Fukuoka igaku zasshi = Hukuoka acta medica. 96, 9, p. 346-350 5 p.

Research output: Contribution to journalArticle

Coronary Artery Disease
Hyperlipidemias
Coronary Artery Bypass
Insulin Resistance
Transplants
2 Citations (Scopus)

B cells as key contributors in determining the level of immune responses -B-cell-targeted therapy in patients with autoimmune diseases

Kondo, S., Akashi, T., Katsuta, H., Iwakiri, R., Anzai, K., Nagafuchi, S., Niho, Y. & Harada, M., Jan 1 2005, In : Fukuoka igaku zasshi = Hukuoka acta medica. 96, 4, p. 86-92 7 p.

Research output: Contribution to journalReview article

Cell- and Tissue-Based Therapy
Autoimmune Diseases
B-Lymphocytes
T-Lymphocytes
Antigen Presentation
6 Citations (Scopus)

cDNA microarray analysis after laser microdissection in proliferating islets of partially pancreatectomized mice

Katsuta, H., Koyanagi-Katsuta, R., Shiiba, M., Anzai, K., Irie, T., Aida, T., Akehi, Y., Nakano, M., Yasunami, Y., Harada, M., Nagafuchi, S., Ono, J. & Tachikawa, T., Dec 1 2005, In : Medical Molecular Morphology. 38, 1, p. 30-35 6 p.

Research output: Contribution to journalReview article

Microdissection
Microarray Analysis
Oligonucleotide Array Sequence Analysis
Lasers
Islets of Langerhans Transplantation
11 Citations (Scopus)

Mitogen-activated protein kinase pathway controls autoimmune regulator (AIRE) gene expression in granulo-monocyte colony stimulating factor (GM-CSF)-stimulated myelomonocytic leukemia OTC-4 cells

Nagafuchi, S., Katsuta, H., Ohno, Y., Inoue, Y., Shimoda, K., Kogawa, K., Ikeda, Y., Koyanagi-Katsuta, R., Yamasaki, S., Tominaga, H., Tamiya, S., Umemura, T., Otsuka, T., Miyamoto, T., Otsuka, T., Harada, M., Kudoh, J. & Shimizu, N., Jun 15 2005, In : Immunology Letters. 99, 1, p. 130-135 6 p.

Research output: Contribution to journalArticle

Colony-Stimulating Factors
Regulator Genes
Mitogen-Activated Protein Kinases
Monocytes
Leukemia
2004
2 Citations (Scopus)

A delayed type hypersensitivity (DTH) skin reaction to hepatitis B surface antigen (HBsAg) and intradermal hepatitis B vaccination.

Nagafuchi, S., Kashiwagi, S., Hayashi, J., Katsuta, H., Ikematsu, H. & Harada, M., Jan 1 2004, In : Fukuoka igaku zasshi = Hukuoka acta medica. 95, 12, p. 305-313 9 p.

Research output: Contribution to journalReview article

Delayed Hypersensitivity
Hepatitis B Surface Antigens
Hepatitis B
Vaccination
Skin
2003
17 Citations (Scopus)

Acceptance of islet allografts in the liver of mice by blockade of an inducible costimulator

Nakamura, Y., Yasunami, Y., Satoh, M., Hirakawa, E., Katsuta, H., Ono, J., Kamada, M., Todo, S., Nakayama, T., Taniguchi, M. & Ikeda, S., Apr 27 2003, In : Transplantation. 75, 8, p. 1115-1118 4 p.

Research output: Contribution to journalArticle

Inducible T-Cell Co-Stimulator Protein
Allografts
Liver
T-Lymphocytes
Antibodies
1 Citation (Scopus)

An autopsy case of Down's syndrome complicated with autoimmune diabetes mellitus and chronic thyroiditis

Akehi, Y., Ogawa, I., Asano, T., Anzai, K., Nakagawachi, R., Katsuta, H., Ohkubo, K., Nishimura, N., Tamura, K. & Ono, J., Aug 4 2003, In : Journal of the Japan Diabetes Society. 46, 6, p. 441-446 6 p.

Research output: Contribution to journalArticle

Down Syndrome
Type 1 Diabetes Mellitus
Autopsy
Diabetes Mellitus
Hashimoto Disease

Current Status of Clinical Islet Transplantation in Japan

Katsuta, H., Anzai, K., Nakano, M., Yasunami, Y. & Ono, J., Oct 31 2003, In : Journal of the Japan Diabetes Society. 46, 9, p. 715-719 5 p.

Research output: Contribution to journalShort survey

Islets of Langerhans Transplantation
Japan
2002
32 Citations (Scopus)

Distinct clinical phenotype and immunoreactivity in Japanese siblings with autoimmune polyglandular syndrome type 1 (APS-1) associated with compound heterozygous novel AIRE gene mutations

Kogawa, K., Kudoh, J., Nagafuchi, S., Ohga, S., Katsuta, H., Ishibashi, H., Harada, M., Hara, T. & Shimizu, N., Jan 1 2002, In : Clinical Immunology. 103, 3 I, p. 277-283 7 p.

Research output: Contribution to journalArticle

Autoimmune Polyendocrinopathies
Regulator Genes
Siblings
Phenotype
Mutation
102 Citations (Scopus)

Expression of AIRE gene in peripheral monocyte/dendritic cell lineage

Kogawa, K., Nagafuchi, S., Katsuta, H., Kudoh, J., Tamiya, S., Sakai, Y., Shimizu, N. & Harada, M., Mar 1 2002, In : Immunology Letters. 80, 3, p. 195-198 4 p.

Research output: Contribution to journalArticle

Cell Lineage
Regulator Genes
Dendritic Cells
Monocytes
Autoimmune Polyendocrinopathies
2 Citations (Scopus)

Retrograde intrafamilial transmission of primary herpes simplex virus type 1 infection [1]

Akashi, T., Minagawa, H., Katsuta, H., Harada, M. & Nagafuchi, S., Jan 1 2002, In : American Journal of Medicine. 113, 1, p. 79-80 2 p.

Research output: Contribution to journalLetter

Human Herpesvirus 1
Virus Diseases
2000
10 Citations (Scopus)

Suppression of insulitis and diabetes in B cell-deficient mice treated with streptozocin: B cells are essential for the TCR clonotype spreading of islet-infiltrating T cells

Kondo, S., Iwata, I., Anzai, K., Akashi, T., Wakana, S., Ohkubo, K., Katsuta, H., Ono, J., Watanabe, T., Niho, Y. & Nagafuchi, S., Jan 1 2000, In : International Immunology. 12, 7, p. 1075-1083 9 p.

Research output: Contribution to journalArticle

Streptozocin
B-Lymphocytes
T-Lymphocytes
Lymphocyte Subsets
Macrophages
1999
33 Citations (Scopus)

Establishment of an embryonic stem (ES) cell line derived from a non-obese diabetic (NOD) mouse: In vivo differentiation into lymphocytes and potential for germ line transmission

Nagafuchi, S., Katsuta, H., Kogawa, K., Akashi, T., Kondo, S., Sakai, Y., Tsukiyama, T., Kitamura, D., Niho, Y. & Watanabe, T., Jul 16 1999, In : FEBS Letters. 455, 1-2, p. 101-104 4 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Lymphocytes
Embryonic Stem Cells
Stem cells
Germ Cells
1998
23 Citations (Scopus)

Cutting edge: Lyn-mediated down-regulation of B cell antigen receptor signaling: Inhibition of protein kinase C activation by Lyn in a kinase- independent fashion

Katsuta, H., Tsuji, S., Niho, Y., Kurosaki, T. & Kitamura, D., Feb 15 1998, In : Journal of Immunology. 160, 4, p. 1547-1551 5 p.

Research output: Contribution to journalArticle

B-Cell Antigen Receptors
Protein Kinase C
B-Lymphocytes
Phosphotransferases
Down-Regulation