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Research Output 1998 2019

2019
3 Citations (Scopus)

A Clinicopathological and Prognostic Analysis of PD-L2 Expression in Surgically Resected Primary Lung Squamous Cell Carcinoma

Matsubara, T., Takada, K., Azuma, K., Takamori, S., Toyokawa, G., Haro, A., Osoegawa, A., Tagawa, T., Kawahara, A., Akiba, J., Okamoto, I., Nakanishi, Y., Oda, Y., Hoshino, T. & Maehara, Y., Jun 15 2019, In : Annals of Surgical Oncology. 26, 6, p. 1925-1933 9 p.

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
Ligands
Lung
CD274 Antigen
Immunotherapy

Association between peripheral blood markers and immune-related factors on tumor cells in patients with resected primary lung adenocarcinoma

Takada, K., Shimokawa, M., Tanaka, K., Kouhashi, K., Haro, A., Osoegawa, A., Tagawa, T., Azuma, K., Okamoto, I., Oda, Y. & Mori, M., Jun 1 2019, In : PloS one. 14, 6, e0217991.

Research output: Contribution to journalArticle

Open Access
Indoleamine-Pyrrole 2,3,-Dioxygenase
Immunologic Factors
adenocarcinoma
Cell death
Tumors

Clinical significance of monitoring EGFR mutation in plasma using multiplexed digital PCR in EGFR mutated patients treated with afatinib (West Japan Oncology Group 8114LTR study)

Akamatsu, H., Koh, Y., Okamoto, I., Fujimoto, D., Bessho, A., Azuma, K., Morita, S., Yamamoto, N. & Nakagawa, K., May 1 2019, In : Lung Cancer. 131, p. 128-133 6 p.

Research output: Contribution to journalArticle

Open Access
Epidermal Growth Factor Receptor
Japan
Polymerase Chain Reaction
Mutation
Non-Small Cell Lung Carcinoma
1 Citation (Scopus)

First-line afatinib for the treatment of EGFR mutation-positive non-small-cell lung cancer in the ‘real-world’ clinical setting

Park, K., Wan-Teck Lim, D., Okamoto, I. & Yang, J. C. H., Apr 1 2019, In : Therapeutic Advances in Medical Oncology. 11

Research output: Contribution to journalReview article

Open Access
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Mutation
Lung
Therapeutics

Genetic Profiling of Non-Small Cell Lung Cancer at Development of Resistance to First- or Second-Generation EGFR-TKIs by CAPP-Seq Analysis of Circulating Tumor DNA

Otsubo, K., Sakai, K., Takeshita, M., Harada, D., Azuma, K., ota, K., Akamatsu, H., Goto, K., Horiike, A., Kurata, T., Nakagaki, N., Nosaki, K., Iwama, E., Nakanishi, Y., Nishio, K. & Okamoto, I., Jan 1 2019, In : Oncologist.

Research output: Contribution to journalArticle

High-Throughput Nucleotide Sequencing
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
DNA

Identification of genomic alterations acquired during treatment with EGFR-TKIs in non-small cell lung cancer

Kubo, N., Harada, T., Shiraishi, Y., Nosaki, K., Nakagaki, N., Takeshita, M., Ouchi, H., Iwama, E., Tanaka, K., Okamoto, I., Sasaki, H. & Nakanishi, Y., Feb 1 2019, In : Anticancer research. 39, 2, p. 671-677 7 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Therapeutics
Exome

Japanese subgroup analysis of a phase III study of S-1 versus docetaxel in non-small cell lung cancer patients after platinum-based treatment: EAST-LC

Sugawara, S., Nakagawa, K., Yamamoto, N., Nokihara, H., Ohe, Y., Nishio, M., Takahashi, T., Goto, K., Maemondo, M., Ichinose, Y., Seto, T., Sakai, H., Gemma, A., Imamura, F., Shingyoji, M., Saka, H., Inoue, A., Takeda, K., Okamoto, I., Kiura, K. & 2 others, Morita, S. & Tamura, T., May 15 2019, In : International Journal of Clinical Oncology. 24, 5, p. 485-493 9 p.

Research output: Contribution to journalArticle

Open Access
docetaxel
Far East
Platinum
Non-Small Cell Lung Carcinoma
Lung Neoplasms

Localized malignant pleural mesothelioma mimicking an anterior mediastinal tumor

Hino, T., Kamitani, T., Sagiyama, K., Yamasaki, Y., Okamoto, I., Tagawa, T., Ijichi, K., Yamamoto, H., Yabuuchi, H. & Honda, H., Jan 1 2019, In : European Journal of Radiology Open. 6, p. 72-77 6 p.

Research output: Contribution to journalArticle

Neoplasms
Pleura
Mediastinum
Differential Diagnosis
Malignant Mesothelioma

Osimertinib versus standard-of-care EGFR-TKI as first-line treatment for EGFRm advanced NSCLC: FLAURA Japanese subset

Ohe, Y., Imamura, F., Nogami, N., Okamoto, I., Kurata, T., Kato, T., Sugawara, S., Ramalingam, S. S., Uchida, H., Hodge, R., Vowler, S. L., Walding, A. & Nakagawa, K., Jan 1 2019, In : Japanese journal of clinical oncology. 49, 1, p. 29-36 8 p.

Research output: Contribution to journalArticle

Standard of Care
Confidence Intervals
Disease-Free Survival
Safety
Therapeutics
2 Citations (Scopus)

Osimertinib versus Standard of Care EGFR TKI as First-Line Treatment in Patients with EGFRm Advanced NSCLC: FLAURA Asian Subset

Cho, B. C., Chewaskulyong, B., Lee, K. H., Dechaphunkul, A., Sriuranpong, V., Imamura, F., Nogami, N., Kurata, T., Okamoto, I., Zhou, C., Cheng, Y., Cho, E. K., Voon, P. J., Lee, J. S., Mann, H., Saggese, M., Reungwetwattana, T., Ramalingam, S. S. & Ohe, Y., Jan 1 2019, In : Journal of Thoracic Oncology. 14, 1, p. 99-106 8 p.

Research output: Contribution to journalArticle

Standard of Care
Protein-Tyrosine Kinases
Disease-Free Survival
Safety
Therapeutics
1 Citation (Scopus)

Pemetrexed and carboplatin combination therapy followed by pemetrexed maintenance in Japanese patients with non-squamous non-small cell lung cancer: A subgroup analysis of elderly patients

Nogami, N., Nishio, M., Okamoto, I., Enatsu, S., Suzukawa, K., Takai, H., Nakagawa, K. & Tamura, T., Jan 1 2019, In : Respiratory Investigation. 57, 1, p. 27-33 7 p.

Research output: Contribution to journalArticle

Pemetrexed
Carboplatin
Non-Small Cell Lung Carcinoma
Maintenance
Therapeutics

Phase I safety and pharmacokinetics study of rovalpituzumab tesirine in Japanese patients with advanced, recurrent small cell lung cancer

Udagawa, H., Akamatsu, H., Tanaka, K., Takeda, M., Kanda, S., Kirita, K., Teraoka, S., Nakagawa, K., Fujiwara, Y., Yasuda, I., Okubo, S., Shintani, M., Kosloski, M. P., Scripture, C., Tamura, T. & Okamoto, I., Sep 1 2019, In : Lung Cancer. 135, p. 145-150 6 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
Pharmacokinetics
Safety
Hypoalbuminemia
Retreatment
2 Citations (Scopus)

Prognostic Impact of Programmed Death-Ligand 2 Expression in Primary Lung Adenocarcinoma Patients

Takamori, S., Takada, K., Azuma, K., Jogo, T., Shimokawa, M., Toyokawa, G., Hirai, F., Tagawa, T., Kawahara, A., Akiba, J., Okamoto, I., Nakanishi, Y., Oda, Y., Hoshino, T. & Maehara, Y., Jun 15 2019, In : Annals of Surgical Oncology. 26, 6, p. 1916-1924 9 p.

Research output: Contribution to journalArticle

Ligands
Adenocarcinoma of lung
Immunotherapy
Disease-Free Survival
Survival

Randomized phase II study of pemetrexed or pemetrexed plus bevacizumab for elderly patients with previously untreated non-squamous non-small cell lung cancer: Results of the Lung Oncology Group in Kyushu (LOGIK1201)

Fukuda, M., Kitazaki, T., Ogawara, D., Ichiki, M., Mukae, H., Maruyama, R., Nakagaki, N., Shimada, M., Ikeda, T., Kishimoto, J., Harada, T., Seto, T., Ebi, N., Takayama, K., Okamoto, I., Ichinose, Y. & Sugio, K., Jun 1 2019, In : Lung Cancer. 132, p. 1-8 8 p.

Research output: Contribution to journalArticle

Pemetrexed
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Disease-Free Survival
Bevacizumab

Safety and efficacy of PD-1 inhibitors in non–small cell lung cancer patients positive for antinuclear antibodies

Yoneshima, Y., Tanaka, K., Shiraishi, Y., Hata, K., Watanabe, H., Harada, T., Otsubo, K., Iwama, E., Inoue, H., Masuda, S., Nakanishi, Y. & Okamoto, I., Apr 1 2019, In : Lung Cancer. 130, p. 5-9 5 p.

Research output: Contribution to journalArticle

Antinuclear Antibodies
Non-Small Cell Lung Carcinoma
Safety
Autoimmune Diseases
Disease-Free Survival
2018
1 Citation (Scopus)

Anticancer drug treatment for advanced lung cancer with interstitial lung disease

Otsubo, K., Okamoto, I., Hamada, N. & Nakanishi, Y., Jul 1 2018, In : Respiratory Investigation. 56, 4, p. 307-311 5 p.

Research output: Contribution to journalReview article

Interstitial Lung Diseases
Lung Neoplasms
Pharmaceutical Preparations
Drug Therapy
Therapeutics

Association of nephrotoxicity during platinum-etoposide doublet therapy with UGT1A1 polymorphisms in small cell lung cancer patients

Anai, S., Iwama, E., Yoneshima, Y., Otsubo, K., Tanaka, K., Nakanishi, Y. & Okamoto, I., Dec 1 2018, In : Lung Cancer. 126, p. 156-161 6 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
Etoposide
Platinum
Alleles
irinotecan
9 Citations (Scopus)

Association of preoperative serum CRP with PD-L1 expression in 508 patients with non-small cell lung cancer: A comprehensive analysis of systemic inflammatory markers

Akamine, T., Takada, K., Toyokawa, G., Kinoshita, F., Matsubara, T., Kozuma, Y., Haratake, N., Takamori, S., Hirai, F., Tagawa, T., Okamoto, T., Yoneshima, Y., Okamoto, I., Shimokawa, M., Oda, Y., Nakanishi, Y. & Maehara, Y., Mar 1 2018, In : Surgical Oncology. 27, 1, p. 88-94 7 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
C-Reactive Protein
Blood Proteins
Ligands
Lymphocytes
5 Citations (Scopus)

Clinical significance of PD-L1 expression in brain metastases from non-small cell lung cancer

Takamori, S., Toyokawa, G., Okamoto, I., Takada, K., Kinoshita, F., Kozuma, Y., Matsubara, T., Haratake, N., Akamine, T., Mukae, N., Hirai, F., Tagawa, T., Oda, Y., Iwaki, T., Iihara, K., Nakanishi, Y. & Maehara, Y., Jan 1 2018, In : Anticancer research. 38, 1, p. 553-557 5 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cell Death
Neoplasm Metastasis
Ligands
Brain
24 Citations (Scopus)

CNS response to osimertinib versus standard epidermal growth factor receptor tyrosine kinase inhibitors in patients with untreated EGFR-mutated advanced non-small-cell lung cancer

Reungwetwattana, T., Nakagawa, K., Cho, B. C., Cobo, M., Cho, E. K., Bertolini, A., Bohnet, S., Zhou, C., Lee, K. H., Nogami, N., Okamoto, I., Leighl, N., Hodge, R., McKeown, A., Brown, A. P., Rukazenkov, Y., Ramalingam, S. S. & Vansteenkiste, J., Nov 20 2018, In : Journal of Clinical Oncology. 36, 33, p. 3290-3297 8 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
osimertinib
Disease-Free Survival
1 Citation (Scopus)

Combined therapy with epidermal growth factor receptor tyrosine kinase inhibitors for non–small cell lung cancer

Iwama, E., Nakanishi, Y. & Okamoto, I., Mar 4 2018, In : Expert Review of Anticancer Therapy. 18, 3, p. 267-276 10 p.

Research output: Contribution to journalReview article

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Mutation
Therapeutics

Detection of identical T cell clones in peritumoral pleural effusion and pneumonitis lesions in a cancer patient during immune-checkpoint blockade

Tanaka, K., Yanagihara, T., Ikematsu, Y., Inoue, H., ota, K., Kashiwagi, E., Suzuki, K., Hamada, N., takeuchi, A., Tatsugami, K., Eto, M., Ijichi, K., Oda, Y., Otsubo, K., Yoneshima, Y., Iwama, E., Nakanishi, Y. & Okamoto, I., Jul 17 2018, In : Oncotarget. 9, 55, p. 30587-30593 7 p.

Research output: Contribution to journalArticle

Bronchoalveolar Lavage Fluid
Pleural Effusion
Pneumonia
Clone Cells
T-Cell Antigen Receptor
1 Citation (Scopus)

Development of leptomeningeal carcinomatosis during a marked response of brain metastases to pembrolizumab in a patient with non-small-cell lung cancer

Otsubo, K., Seki, N., Nakanishi, Y. & Okamoto, I., Mar 1 2018, In : Annals of Oncology. 29, 3, p. 780-781 2 p.

Research output: Contribution to journalLetter

Meningeal Carcinomatosis
Non-Small Cell Lung Carcinoma
Neoplasm Metastasis
Brain
pembrolizumab
1 Citation (Scopus)

Durable response to nivolumab in a lung adenocarcinoma patient with idiopathic pulmonary fibrosis

Ide, M., Tanaka, K., Sunami, S., Asoh, T., Maeyama, T., Tsuruta, N., Nakanishi, Y. & Okamoto, I., Nov 1 2018, In : Thoracic Cancer. 9, 11, p. 1519-1521 3 p.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Non-Small Cell Lung Carcinoma
Pleurisy
Respiratory Function Tests
Neoplasms
4 Citations (Scopus)

Erlotinib Plus Bevacizumab Phase ll Study in Patients with Advanced Non-small-Cell Lung Cancer (JO25567): Updated Safety Results

Kato, T., Seto, T., Nishio, M., Goto, K., Yamamoto, N., Okamoto, I., Tao, L., Yu, W., Khaznadar, T., Tajima, K., Shibata, M., Seki, A. & Yamamoto, N., Feb 1 2018, In : Drug Safety. 41, 2, p. 229-237 9 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cells
Safety
Epidermal Growth Factor Receptor
Mutation
1 Citation (Scopus)

Exploration of resistance mechanisms for epidermal growth factor receptor-tyrosine kinase inhibitors based on plasma analysis by digital polymerase chain reaction and next-generation sequencing

Iwama, E., Sakai, K., Azuma, K., Harada, D., Nosaki, K., Hotta, K., Nishio, M., Kurata, T., Fukuhara, T., Akamatsu, H., Goto, K., Shimose, T., Kishimoto, J., Nakanishi, Y., Nishio, K. & Okamoto, I., Dec 1 2018, In : Cancer Science. 109, 12, p. 3921-3933 13 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Polymerase Chain Reaction
Mutation
Neoplasms

Expression of brain-derived neurotrophic factor and its receptor TrkB is associated with poor prognosis and a malignant phenotype in small cell lung cancer

Kimura, S., Harada, T., Ijichi, K., Tanaka, K., Liu, R., Shibahara, D., Kawano, Y., Otsubo, K., Yoneshima, Y., Iwama, E., Nakanishi, Y. & Okamoto, I., Jun 1 2018, In : Lung Cancer. 120, p. 98-107 10 p.

Research output: Contribution to journalArticle

trkB Receptor
Brain-Derived Neurotrophic Factor
Small Cell Lung Carcinoma
Phenotype
Non-Small Cell Lung Carcinoma
2 Citations (Scopus)

Heterogeneous distribution of alectinib in neuroblastoma xenografts revealed by matrix-assisted laser desorption ionization mass spectrometry imaging: a pilot study

Ryu, S., Hayashi, M., Aikawa, H., Okamoto, I., Fujiwara, Y. & Hamada, A., Jan 1 2018, In : British Journal of Pharmacology. 175, 1, p. 29-37 9 p.

Research output: Contribution to journalArticle

Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Neuroblastoma
Heterografts
Lasers
Ions
4 Citations (Scopus)

Intrinsic and Extrinsic Regulation of PD-L2 Expression in Oncogene-Driven Non–Small Cell Lung Cancer

Shibahara, D., Tanaka, K., Iwama, E., Kubo, N., ota, K., Azuma, K., Harada, T., Fujita, J., Nakanishi, Y. & Okamoto, I., Jul 1 2018, In : Journal of Thoracic Oncology. 13, 7, p. 926-937 12 p.

Research output: Contribution to journalArticle

Oncogenes
Non-Small Cell Lung Carcinoma
Cell Death
Ligands
STAT3 Transcription Factor

Metastatic lung adenocarcinoma mimicking meningioma

Yanagihara, T., Seki, N., Akio, H., Arimura, K., Suzuki, S. & Okamoto, I., Jan 1 2018, In : Internal Medicine. 57, 7, p. 1057-1058 2 p.

Research output: Contribution to journalComment/debate

Meningioma
Adenocarcinoma of lung
5 Citations (Scopus)

Osimertinib in Japanese patients with EGFR T790M mutation-positive advanced non-small-cell lung cancer: AURA3 trial

Akamatsu, H., Katakami, N., Okamoto, I., Kato, T., Kim, Y. H., Imamura, F., Shinkai, M., Hodge, R. A., Uchida, H. & Hida, T., Jun 1 2018, In : Cancer Science. 109, 6, p. 1930-1938 9 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Pemetrexed
Mutation
Protein-Tyrosine Kinases

Osimertinib in patients with epidermal growth factor receptor T790M advanced non-small cell lung cancer selected using cytology samples

Kiura, K., Yoh, K., Katakami, N., Nogami, N., Kasahara, K., Takahashi, T., Okamoto, I., Cantarini, M., Hodge, R. & Uchida, H., Apr 1 2018, In : Cancer Science. 109, 4, p. 1177-1184 8 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Cell Biology
Mutation
Confidence Intervals
409 Citations (Scopus)

Osimertinib in untreated EGFR-Mutated advanced non-small-cell lung cancer

Soria, J. C., Ohe, Y., Vansteenkiste, J., Reungwetwattana, T., Chewaskulyong, B., Lee, K. H., Dechaphunkul, A., Imamura, F., Nogami, N., Kurata, T., Okamoto, I., Zhou, C., Cho, B. C., Cheng, Y., Cho, E. K., Voon, P. J., Planchard, D., Su, W. C., Gray, J. E., Lee, S. M. & 4 others, Hodge, R., Marotti, M., Rukazenkov, Y. & Ramalingam, S. S., Jan 11 2018, In : New England Journal of Medicine. 378, 2, p. 113-125 13 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Confidence Intervals
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Mutation
10 Citations (Scopus)

PD-L1 expression in lung adenocarcinoma harboring EGFR mutations or ALK rearrangements

Yoneshima, Y., Ijichi, K., Anai, S., ota, K., Otsubo, K., Iwama, E., Tanaka, K., Oda, Y., Nakanishi, Y. & Okamoto, I., Apr 1 2018, In : Lung Cancer. 118, p. 36-40 5 p.

Research output: Contribution to journalArticle

Mutation
Neoplasms
Adenocarcinoma of lung
Protein-Tyrosine Kinases
Oncogenes
5 Citations (Scopus)

PD-L2 expression as a potential predictive biomarker for the response to anti-PD-1 drugs in patients with non-small cell lung cancer

Takamori, S., Takada, K., Toyokawa, G., Azuma, K., Shimokawa, M., Jogo, T., Yamada, Y., Hirai, F., Tagawa, T., Kawahara, A., Akiba, J., Okamoto, I., Nakanishi, Y., Oda, Y., Hoshino, T. & Maehara, Y., Oct 1 2018, In : Anticancer research. 38, 10, p. 5897-5901 5 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cell Death
Biomarkers
Ligands
Pharmaceutical Preparations
4 Citations (Scopus)

Phase 3 study of ceritinib vs chemotherapy in ALK-rearranged NSCLC patients previously treated with chemotherapy and crizotinib (ASCEND-5): Japanese subset

Kiura, K., Imamura, F., Kagamu, H., Matsumoto, S., Hida, T., Nakagawa, K., Satouchi, M., Okamoto, I., Takenoyama, M., Fujisaka, Y., Kurata, T., Ito, M., Tokushige, K., Hatano, B. & Nishio, M., Apr 1 2018, In : Japanese journal of clinical oncology. 48, 4, p. 367-375 9 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Drug Therapy
docetaxel
Pemetrexed
Disease-Free Survival
2 Citations (Scopus)

Phase I/II study of carboplatin plus nab-paclitaxel and concurrent radiotherapy for patients with locally advanced non–small cell lung cancer

Kawano, Y., Sasaki, T., Yamaguchi, H., Hirano, K., Horiike, A., Satouchi, M., Hosokawa, S., Morinaga, R., Komiya, K., Inoue, K., Fujita, Y., Toyozawa, R., Kimura, T., Takahashi, K., Nishikawa, K., Kishimoto, J., Nakanishi, Y. & Okamoto, I., Nov 1 2018, In : Lung Cancer. 125, p. 136-141 6 p.

Research output: Contribution to journalArticle

Carboplatin
Non-Small Cell Lung Carcinoma
Radiotherapy
Leukopenia
Confidence Intervals
1 Citation (Scopus)
Therapeutic Uses
Platinum
Non-Small Cell Lung Carcinoma
Perfusion
Tomography
11 Citations (Scopus)

Prevalence of Delta-like protein 3 expression in patients with small cell lung cancer

Tanaka, K., Isse, K., Fujihira, T., Takenoyama, M., Saunders, L., Bheddah, S., Nakanishi, Y. & Okamoto, I., Jan 1 2018, In : Lung Cancer. 115, p. 116-120 5 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
delta protein
Neoplasms
Sex Characteristics
Japan
1 Citation (Scopus)

Prognostic impact of PD-L2 expression and association with PD-L1 in patients with small-cell lung cancer

Takamori, S., Takada, K., Azuma, K., Jogo, Y., Kinoshita, F., Kozuma, Y., Matsubara, T., Haratake, N., Akamine, T., Toyokawa, G., Hirai, F., Tagawa, T., Okamoto, I., Nakanishi, Y., Kawahara, A., Akiba, J., Oda, Y. & Maehara, Y., Oct 1 2018, In : Anticancer research. 38, 10, p. 5903-5907 5 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
Cell Death
Ligands
Lung Neoplasms
Programmed Cell Death 1 Ligand 2 Protein
1 Citation (Scopus)

Radiological features of programmed cell death-ligand 2-positive lung adenocarcinoma: A single-institution retrospective study

Takada, K., Toyokawa, G., Azuma, K., Takamori, S., Jogo, T., Hirai, F., Tagawa, T., Kawahara, A., Akiba, J., Okamoto, I., Nakanishi, Y., Oda, Y., Hoshino, T. & Maehara, Y., Nov 1 2018, In : In Vivo. 32, 6, p. 1541-1550 10 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Cell death
Tomography
Cell Death
Retrospective Studies
10 Citations (Scopus)

Real world treatment and outcomes in EGFR mutation-positive non-small cell lung cancer: Long-term follow-up of a large patient cohort

Okamoto, I., Morita, S., Tashiro, N., Imamura, F., Inoue, A., Seto, T., Yamamoto, N., Ohe, Y., Nakagawa, K. & Fukuoka, M., Mar 1 2018, In : Lung Cancer. 117, p. 14-19 6 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Mutation
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Survival

Sensitivity of epidermal growth factor receptor with single or double uncommon mutations to afatinib confirmed by a visual assay

Kimura, S., Tanaka, K., Harada, T., Liu, R., Shibahara, D., Kawano, Y., Nakanishi, Y. & Okamoto, I., Nov 1 2018, In : Cancer Science. 109, 11, p. 3657-3661 5 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Mutation
Protein-Tyrosine Kinases
Non-Small Cell Lung Carcinoma
BIBW 2992
8 Citations (Scopus)

Treatment Rationale and Design for J-SONIC: A Randomized Study of Carboplatin Plus Nab-paclitaxel With or Without Nintedanib for Advanced Non–Small-cell Lung Cancer With Idiopathic Pulmonary Fibrosis

Otsubo, K., Kishimoto, J., Kenmotsu, H., Minegishi, Y., Ichihara, E., Shiraki, A., Kato, T., Atagi, S., Horinouchi, H., Ando, M., Kondoh, Y., Kusumoto, M., Ichikado, K., Yamamoto, N., Nakanishi, Y. & Okamoto, I., Jan 1 2018, In : Clinical Lung Cancer. 19, 1, p. e5-e9

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Carboplatin
Non-Small Cell Lung Carcinoma
Nanoparticles
Therapeutics
2017
11 Citations (Scopus)

Alectinib for Patients with ALK Rearrangement–Positive Non–Small Cell Lung Cancer and a Poor Performance Status (Lung Oncology Group in Kyushu 1401)

Iwama, E., Goto, Y., Murakami, H., Harada, T., Tsumura, S., Sakashita, H., Mori, Y., Nakagaki, N., Fujita, Y., Seike, M., Bessho, A., Ono, M., Okazaki, A., Akamatsu, H., Morinaga, R., Ushijima, S., Shimose, T., Tokunaga, S., Hamada, A., Yamamoto, N. & 3 others, Nakanishi, Y., Sugio, K. & Okamoto, I., Jul 1 2017, In : Journal of Thoracic Oncology. 12, 7, p. 1161-1166 6 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Lung
Confidence Intervals
Patient Safety
CH5424802
6 Citations (Scopus)

A Randomized Phase II Study Comparing Nivolumab With Carboplatin-Pemetrexed for Patients With EGFR Mutation–Positive Nonsquamous Non–Small-Cell Lung Cancer Who Acquire Resistance to Tyrosine Kinase Inhibitors Not Due to a Secondary T790M Mutation: Rationale and Protocol Design for the WJOG8515L Study

Hayashi, H., Chiba, Y., Sakai, K., Fujita, T., Yoshioka, H., Sakai, D., Kitagawa, C., Naito, T., Takeda, K., Okamoto, I., Mitsudomi, T., Kawakami, Y., Nishio, K., Nakamura, S., Yamamoto, N. & Nakagawa, K., Nov 1 2017, In : Clinical Lung Cancer. 18, 6, p. 719-723 5 p.

Research output: Contribution to journalArticle

Pemetrexed
erbB-1 Genes
Carboplatin
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
3 Citations (Scopus)

CD44 variant–dependent regulation of redox balance in EGFR mutation–positive non–small cell lung cancer: A target for treatment

Kawano, Y., Iwama, E., Tsuchihashi, K., Shibahara, D., Harada, T., Tanaka, K., Nagano, O., Saya, H., Nakanishi, Y. & Okamoto, I., Nov 1 2017, In : Lung Cancer. 113, p. 72-78 7 p.

Research output: Contribution to journalArticle

erbB-1 Genes
Non-Small Cell Lung Carcinoma
Oxidation-Reduction
Reactive Oxygen Species
Cisplatin
1 Citation (Scopus)

Chronic myelomonocytic leukemia blast crisis in a patient with advanced non-small cell lung cancer treated with EGFR tyrosine kinase inhibitors

Ogata, H., Okamoto, I., Yoshimoto, G., Obara, T., Ijichi, K., Iwama, E., Harada, T., Akashi, K. & Nakanishi, Y., Mar 1 2017, In : Respiratory Investigation. 55, 2, p. 181-183 3 p.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
erbB-1 Genes
Blast Crisis
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
12 Citations (Scopus)

Discrepancy in programmed cell death-ligand 1 between primary and metastatic non-small cell lung cancer

Takamori, S., Toyokawa, G., Okamoto, I., Takada, K., Kozuma, Y., Matsubara, T., Haratake, N., Akamine, T., Katsura, M., Mukae, N., Shoji, F., Okamoto, T., Oda, Y., Iwaki, T., Iihara, K., Nakanishi, Y. & Maehara, Y., Aug 1 2017, In : Anticancer research. 37, 8, p. 4223-4228 6 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cell Death
Ligands
Radiotherapy
Brain
5 Citations (Scopus)

Marked response to pembrolizumab in a patient with pulmonary pleomorphic carcinoma highly positive for PD-L1

Ikematsu, Y., Yoneshima, Y., Ijichi, K., Tanaka, K., Harada, T., Oda, Y., Nakanishi, Y. & Okamoto, I., Oct 1 2017, In : Lung Cancer. 112, p. 230-231 2 p.

Research output: Contribution to journalLetter

Carcinoma
Lung
pembrolizumab