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Research Output 1981 2019

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Article
2019
1 Citation (Scopus)

A novel model for treatment of hypertrophic pachymeningitis

Cui, Y., Masaki, K., Zhang, X., Yamasaki, R., Fujii, T., Ogata, H., Hayashida, S., Yamaguchi, H., Hyodo, F., Eto, H., Koyama, S., Iinuma, K., Yonekawa, T., Matsushita, T., Yoshida, M., Yamada, K., Kawano, M., Malissen, M., Malissen, B. & Kira, J., Mar 2019, In : Annals of Clinical and Translational Neurology. 6, 3, p. 431-444 14 p.

Research output: Contribution to journalArticle

Open Access
Transforming Growth Factors
Meningitis
irbesartan
Immunoglobulin G
B-Lymphocytes

A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis

International Multiple Sclerosis Genetics Consortium, Dec 1 2019, In : Nature communications. 10, 1, 2236.

Research output: Contribution to journalArticle

Open Access
Systems Biology
Regulator Genes
biology
genes
genome

Brainstem posterior reversible encephalopathy syndrome in a case with Guillain–Barré syndrome

Yokoyama, J., Yamaguchi, H., Koge, J., Matsushita, T., Isobe, N., Yamasaki, R. & Kira, J. I., Nov 1 2019, In : Clinical and Experimental Neuroimmunology. 10, 4, p. 267-271 5 p.

Research output: Contribution to journalArticle

Posterior Leukoencephalopathy Syndrome
Brain Stem
Consciousness
Passive Immunization
Intravenous Immunoglobulins

Case of central nervous system inflammatory disease in late pregnancy

Isobe, N., Baba, T., Nakamura, Y., Shinoda, K., Watanabe, M., Matsushita, T. & Kira, J. I., Mar 2019, In : Clinical and Experimental Neuroimmunology. 10, S1, p. 54-58 5 p.

Research output: Contribution to journalArticle

Open Access
Central Nervous System Diseases
Pregnancy
Dysarthria
Myoclonus
Hypesthesia
1 Citation (Scopus)

Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis

Harada, Y., Zhang, J., Imari, K., Yamasaki, R., Ni, J., Take, H., Yamamoto, K., Kira, J-I., Nakanishi, H. & Hayashi, Y., Sep 1 2019, In : Pain. 160, 9, p. 2050-2062 13 p.

Research output: Contribution to journalArticle

Cathepsin E
Autoimmune Experimental Encephalomyelitis
Neuralgia
Neutrophils
Hyperalgesia

Cerebrospinal fluid cytokine/chemokine/growth factor profiles in idiopathic hypertrophic pachymeningitis

Zhang, X., Fujii, T., Ogata, H., Yamasaki, R., Masaki, K., Cui, Y., Matsushita, T., Isobe, N. & Kira, J-I., May 15 2019, In : Journal of Neuroimmunology. 330, p. 38-43 6 p.

Research output: Contribution to journalArticle

Nervous System Diseases
Meningitis
Chemokines
Cerebrospinal Fluid
Intercellular Signaling Peptides and Proteins

Cognition with magnetic resonance imaging findings and social activities in patients with multiple sclerosis in a Japanese cohort

Niino, M., Fukazawa, T., Kira, J. I., Okuno, T., Mori, M., Sanjo, N., Ohashi, T., Fukaura, H., Fujimori, J., Shimizu, Y., Mifune, N., Miyazaki, Y., Takahashi, E., Kikuchi, S., Langdon, D., Benedict, R. H. B. & Matsui, M., Feb 1 2019, In : Clinical and Experimental Neuroimmunology. 10, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

Cognition
Multiple Sclerosis
Magnetic Resonance Imaging
Verbal Learning
Analysis of Variance
Chronic Progressive Multiple Sclerosis
Neuroimaging
Cross-Sectional Studies
Oligoclonal Bands
Colony-Stimulating Factor Receptors
1 Citation (Scopus)
Gyrus Cinguli
Alzheimer Disease
Temporal Lobe
Brain
Frontal Lobe

Grand Total EEG score can differentiate Parkinson's disease from Parkinson-related disorders

Barcelon, E. A., Mukaino, T., Yokoyama, J., Uehara, T., Ogata, K., Kira, J. I. & Tobimatsu, S., Jan 1 2019, In : Frontiers in Neurology. 10, APR, 398.

Research output: Contribution to journalArticle

Open Access
Parkinson Disease
Electroencephalography
Parkinsonian Disorders
Multiple System Atrophy
Paralysis

Higher postictal parasympathetic activity following greater ictal heart rate increase in right- than left-sided seizures

Shimmura, M., Uehara, T., Ogata, K., Shigeto, H., Maeda, T., Sakata, A., Yamasaki, R. & Kira, J-I., Aug 1 2019, In : Epilepsy and Behavior. 97, p. 161-168 8 p.

Research output: Contribution to journalArticle

Seizures
Heart Rate
Stroke
ROC Curve
Partial Epilepsy

Intractable axonal neuropathy with multifocal peripheral nerve swelling in neuromyelitis optica spectrum disorders: A case report

Mizuno, Y., Shinoda, K., Watanabe, M., Ogata, H., Isobe, N., Matsushita, T., Yamasaki, R., Tanaka, K., Koike, H., Katsuno, M. & Kira, J. I., Oct 2019, In : Multiple Sclerosis and Related Disorders. 35, p. 16-18 3 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Peripheral Nerves
Upper Extremity
Aquaporin 4
Magnetic Resonance Spectroscopy

Intrathecal cytokine profile in neuropathy with anti-neurofascin 155 antibody

Ogata, H., Zhang, X., Yamasaki, R., Fujii, T., Machida, A., Morimoto, N., Kaida, K., Masuda, T., Ando, Y., Kuwahara, M., Kusunoki, S., Nakamura, Y., Matsushita, T., Isobe, N. & Kira, J. I., Nov 1 2019, In : Annals of Clinical and Translational Neurology. 6, 11, p. 2304-2316 13 p.

Research output: Contribution to journalArticle

Open Access
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Cytokines
Antibodies
Interleukin-13
Interleukin-8

Long-term use of interferon-β in multiple sclerosis increases Vδ1-Vδ2-Vγ9- γδ T cells that are associated with a better outcome

Maimaitijiang, G., watanabe, M., Shinoda, K., Isobe, N., Nakamura, Y., Masaki, K., Matsushita, T., Yoshikai, Y. & Kira, J-I., Sep 13 2019, In : Journal of neuroinflammation. 16, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Interferons
Multiple Sclerosis
T-Lymphocytes
B-Lymphocytes
T-Lymphocyte Subsets
3 Citations (Scopus)

MOG antibody disease manifesting as progressive cognitive deterioration and behavioral changes with primary central nervous system vasculitis

Baba, T., Shinoda, K., watanabe, M., Sadashima, S., Matsuse, D., Isobe, N., Yamasaki, R., Kaneko, K., Takahashi, T., Iwaki, T. & Kira, J-I., May 1 2019, In : Multiple Sclerosis and Related Disorders. 30, p. 48-50 3 p.

Research output: Contribution to journalArticle

Myelin-Oligodendrocyte Glycoprotein
Central Nervous System Vasculitis
Immunotherapy
Antibodies
Cerebrum

Serum GFAP and neurofilament light as biomarkers of disease activity and disability in NMOSD

Watanabe, M., Nakamura, Y., Michalak, Z., Isobe, N., Barro, C., Leppert, D., Matsushita, T., Hayashi, F., Yamasaki, R., Kuhle, J. & Kira, J. I., Sep 24 2019, In : Neurology. 93, 13, p. e1299-e1311

Research output: Contribution to journalArticle

Neuromyelitis Optica
Intermediate Filaments
Glial Fibrillary Acidic Protein
Blood Proteins
Biomarkers
3 Citations (Scopus)

Simultaneous MR neurography and apparent T2 mapping in brachial plexus: Evaluation of patients with chronic inflammatory demyelinating polyradiculoneuropathy

Akio, H., Togao, O., Yamashita, K., kikuchi, K., Momosaka, D., Nakatake, H., Yamasaki, R., Ogata, H., Yoneyama, M., Kira, J-I. & Honda, H., Jan 1 2019, In : Magnetic Resonance Imaging. 55, p. 112-117 6 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Brachial Plexus
Relaxation time
Healthy Volunteers
Ganglia

Spinal cord involvement by atrophy and associations with disability are different between multiple sclerosis and neuromyelitis optica spectrum disorder

Nakamura, Y., Liu, Z., Fukumoto, S., Shinoda, K., Sakoda, A., Matsushita, T., Hayashida, S., Isobe, N., Watanabe, M., Hiwatashi, A., Yamasaki, R. & Kira, J-I., Jan 1 2019, (Accepted/In press) In : European Journal of Neurology.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Multiple Sclerosis
Atrophy
Spinal Cord
Thorax
1 Citation (Scopus)

Temporal Trends in Clinical Characteristics and Door-to-Needle Time in Patients Receiving Intravenous Tissue Plasminogen Activator: A Retrospective Study of 4 Hospitals in Japan

Tanaka, K., Matsumoto, S., Yamada, T., Nagano, S., Takase, K. I., Hatano, T., Yamasaki, R. & Kira, J-I., Jan 1 2019, (Accepted/In press) In : Journal of Stroke and Cerebrovascular Diseases. 104305.

Research output: Contribution to journalArticle

Tissue Plasminogen Activator
Needles
Japan
Retrospective Studies
Stroke
2 Citations (Scopus)

Toxic myopathy with multiple deletions in mitochondrial DNA associated with long-term use of oral anti-viral drugs for hepatitis B: A case study

Fujii, T., Takase, K. I., Honda, H., Kawamura, N., Yamasaki, R., Urata, M., Uchiumi, T., Iwaki, T. & Kira, J-I., Apr 1 2019, In : Neuropathology. 39, 2, p. 162-167 6 p.

Research output: Contribution to journalArticle

Poisons
Muscular Diseases
Hepatitis B
Mitochondrial DNA
Nucleosides
2018
1 Citation (Scopus)

A case of multiple system atrophy-parkinsonian type with stuttering- and palilalia-like dysfluencies and putaminal atrophy

Kikuchi, Y., Umezaki, T., Uehara, T., yamaguchi, H., Yamashita, K., Akio, H., Sawatsubashi, M., Adachi, K., Yamaguchi, Y., Murakami, D., Kira, J-I. & Nakagawa, T., Sep 1 2018, In : Journal of Fluency Disorders. 57, p. 51-58 8 p.

Research output: Contribution to journalArticle

Multiple System Atrophy
Stuttering
Atrophy
deficit
Putamen
2 Citations (Scopus)

A comparison of brain magnetic resonance imaging lesions in multiple sclerosis by race with reference to disability progression

Nakamura, Y., Gaetano, L., Matsushita, T., Anna, A., Sprenger, T., Radue, E. W., Wuerfel, J., Bauer, L., Amann, M., Shinoda, K., Isobe, N., Yamasaki, R., Saida, T., Kappos, L. & Kira, J. I., Sep 5 2018, In : Journal of neuroinflammation. 15, 1, 255.

Research output: Contribution to journalArticle

Multiple Sclerosis
Magnetic Resonance Imaging
Brain
Atrophy
Relapsing-Remitting Multiple Sclerosis
1 Citation (Scopus)

A Novel Autoantibody against Plexin D1 in Patients with Neuropathic Pain

Fujii, T., Yamasaki, R., Iinuma, K., Tsuchimoto, D., Hayashi, Y., Saitoh, B. Y., Matsushita, T., Kido, M. A., Aishima, S., Nakanishi, H., Nakabeppu, Y. & Kira, J. I., Aug 2018, In : Annals of Neurology. 84, 2, p. 208-224 17 p.

Research output: Contribution to journalArticle

Neuralgia
Autoantibodies
Spinal Ganglia
Neurons
Unmyelinated Nerve Fibers
2 Citations (Scopus)

Association of decreased percentage of Vδ2+Vγ9+ γδ T cells with disease severity in multiple sclerosis

Maimaitijiang, G., Shinoda, K., Nakamura, Y., Masaki, K., Matsushita, T., Isobe, N., Yamasaki, R., Yoshikai, Y. & Kira, J. I., Apr 10 2018, In : Frontiers in Immunology. 9, APR, 748.

Research output: Contribution to journalArticle

Multiple Sclerosis
T-Lymphocytes
Interferons
T-Cell Receptor Genes
T-Lymphocyte Gene Rearrangement
4 Citations (Scopus)

Chronic inflammatory demyelinating polyneuropathy with concurrent membranous nephropathy: An anti-paranode and podocyte protein antibody study and literature survey

Hashimoto, Y., Ogata, H., Yamasaki, R., Sasaguri, T., Ko, S., yamashita, K., Xu, Z., Matsushita, T., Tateishi, T., Akiyama, SI., Maruyama, S., Yamamoto, A. & Kira, J-I., Nov 27 2018, In : Frontiers in Neurology. 9, NOV, 00997.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Contactin 1
Podocytes
Membranous Glomerulonephritis
Antibodies
5 Citations (Scopus)
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Connexins
varespladib methyl
Astrocytes
Parkinson Disease
2 Citations (Scopus)
Connexins
Autoimmune Experimental Encephalomyelitis
Microglia
Connexin 43
Knockout Mice
Electrical Synapses
Anterior Horn Cells
Presynaptic Terminals
Amyotrophic Lateral Sclerosis
Down-Regulation
1 Citation (Scopus)

Duplication and deletion upstream of LMNB1 in autosomal dominant adult-onset leukodystrophy

Mezaki, N., Miura, T., Ogaki, K., Eriguchi, M., Mizuno, Y., Komatsu, K., Yamazaki, H., Suetsugi, N., Kawajiri, S., Yamasaki, R., Ishiguro, T., Konno, T., Nozaki, H., Kasuga, K., Okuma, Y., Kira, J-I., Hara, H., Onodera, O. & Ikeuchi, T., Dec 1 2018, In : Neurology: Genetics. 4, 6, e292.

Research output: Contribution to journalArticle

lamin B1
Leukoencephalopathies
Temporal Lobe
Reverse Transcription
Leukocytes
7 Citations (Scopus)

ELectron microscopic abnormality and therapeutic efficacy in chronic inflammatory demyelinating polyneuropathy with anti-neurofascin155 immunoglobulin G4 antibody

Kuwahara, M., Suzuki, H., Oka, N., Ogata, H., Yanagimoto, S., Sadakane, S., Fukumoto, Y., Yamana, M., Yuhara, Y., Yoshikawa, K., Morikawa, M., Kawai, S., Okazaki, M., Tsujimoto, T., Kira, J-I. & Kusunoki, S., Mar 1 2018, In : Muscle and Nerve. 57, 3, p. 498-502 5 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Immunoglobulins
Electrons
Antibodies
Sural Nerve

Elevated end-diastolic ratio of the common carotid artery due to cerebral arteriovenous malformation: Two case reports

Tanaka, K., Matsumoto, S., Yamada, T., Kondo, D., Chihara, H., Koga, M., Hatano, T., Miyagi, T., Yamasaki, R. & Kira, J. I., Aug 2018, In : Radiology Case Reports. 13, 4, p. 917-920 4 p.

Research output: Contribution to journalArticle

Intracranial Arteriovenous Malformations
Common Carotid Artery
Cerebral Veins
Nervous System Malformations
Headache Disorders

Hopkins syndrome following the first episode of bronchial asthma associated with enterovirus D68: A case report

Hayashi, F., Hayashi, S., Matsuse, D., Yamasaki, R., Yonekura, K. & Kira, J. I., May 23 2018, In : BMC neurology. 18, 1, 71.

Research output: Contribution to journalArticle

Enterovirus
Asthma
Respiratory Hypersensitivity
Lower Extremity
Adult Respiratory Distress Syndrome
2 Citations (Scopus)

Lumbar plexus in patients with chronic inflammatory demyelinating polyradiculoneuropathy: Evaluation with simultaneous T 2 mapping and neurography method with SHINKEI

Akio, H., Togao, O., Yamashita, K., kikuchi, K., Momosaka, D., Nakatake, H., Yamasaki, R., Ogata, H., Yoneyama, M., Kira, J-I. & Honda, H., Jan 1 2018, In : British Journal of Radiology. 91, 1092, 20180501.

Research output: Contribution to journalArticle

Lumbosacral Plexus
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Spinal Ganglia
ROC Curve
Research Ethics Committees

Mitochondrial dysfunction and altered ribostasis in hippocampal neurons with cytoplasmic inclusions of multiple system atrophy

Maeda, N., Honda, H., Suzuki, S., Fujii, N., Kira, J-I. & Iwaki, T., Aug 1 2018, In : Neuropathology. 38, 4, p. 361-371 11 p.

Research output: Contribution to journalArticle

Multiple System Atrophy
Inclusion Bodies
Neurons
Hippocampus
Heterogeneous-Nuclear Ribonucleoproteins
5 Citations (Scopus)
Antirheumatic Agents
Autoimmune Experimental Encephalomyelitis
Macrophage Activation
Microglia
Demyelinating Diseases

Oral phase dysphagia in facial onset sensory and motor neuronopathy

watanabe, M., Shiraishi, W., Yamasaki, R., Isobe, N., Sawatsubashi, M., Yasumatsu, R., Nakagawa, T. & Kira, J-I., Jun 1 2018, In : Brain and Behavior. 8, 6, e00999.

Research output: Contribution to journalArticle

Deglutition Disorders
Deglutition
Pharynx
Aspiration Pneumonia
Gastrostomy
6 Citations (Scopus)
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Antibodies
Neural Conduction
Immunotherapy
Cerebrospinal Fluid Proteins
3 Citations (Scopus)

Restoration of a conduction block after the long-term treatment of CIDP with anti-neurofascin 155 antibodies: Follow-up of a case over 23 years

Koike, H., Nishi, R., Ikeda, S., Kawagashira, Y., Iijima, M., Atsuta, N., Nakamura, T., Hirayama, M., Ogata, H., Yamasaki, R., Kira, J. I., Katsuno, M. & Sobue, G., Jan 1 2018, In : Internal Medicine. 57, 14, p. 2061-2066 6 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Hypesthesia
Antibodies
Neural Conduction
Action Potentials

The contribution of glial inflammation in the pathogenesis of multiple sclerosis

Yamasaki, R. & Kira, J-I., Jan 1 2018, In : Neuro-Ophthalmology Japan. 35, 1, p. 4-10 7 p.

Research output: Contribution to journalArticle

Connexins
Neuroglia
Multiple Sclerosis
Inflammation
Recurrence

The neuropathological study of myelin oligodendrocyte glycoprotein in the temporal lobe of schizophrenia patients

Marui, T., Torii, Y., Iritani, S., Sekiguchi, H., Habuchi, C., Fujishiro, H., Oshima, K., Niizato, K., Hayashida, S., Masaki, K., Kira, J-I. & Ozaki, N., Aug 1 2018, In : Acta Neuropsychiatrica. 30, 4, p. 232-240 9 p.

Research output: Contribution to journalArticle

Myelin-Oligodendrocyte Glycoprotein
Temporal Lobe
Schizophrenia
Oligodendroglia
Brain
Vesicular Glutamate Transport Protein 2
STAT3 Transcription Factor
Transcriptional Activation
Glutamic Acid
Spinal Cord
2017
3 Citations (Scopus)

A case of anti-neurofascin 155 antibody-positive combined central and peripheral demyelination successfully treated with plasma exchange

Shimizu, M., Koda, T., Nakatsuji, Y., Ogata, H., Kira, J-I. & Mochizuki, H., Jan 1 2017, In : Clinical Neurology. 57, 1, p. 41-44 4 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Plasma Exchange
Demyelinating Diseases
Cerebrospinal Fluid
Anti-Idiotypic Antibodies

A case of stiff-person syndrome due to secondary adrenal insufficiency

Mizuno, Y., yamaguchi, H., Uehara, T., yamashita, K., Yamasaki, R. & Kira, J-I., Jan 1 2017, In : Clinical Neurology. 57, 6, p. 298-302 5 p.

Research output: Contribution to journalArticle

Stiff-Person Syndrome
Adrenal Insufficiency
Contracture
Hypopituitarism
Muscles

A case of superficial siderosis ameliorated after closure of dural deficit detected by MRI-CISS (constructive interference in steady state) imaging

Sakoda, A., Yamashita, K. I., Hayashida, M., Iwamoto, Y., Yamasaki, R. & Kira, J. I., Jan 1 2017, In : Clinical Neurology. 57, 4, p. 180-183 4 p.

Research output: Contribution to journalArticle

Siderosis
Dizziness
Ataxia
Headache
Cerebrospinal Fluid
2 Citations (Scopus)

A novel mutation in FGD4 causes Charcot–Marie–Tooth disease type 4H with cranial nerve involvement

Kondo, D., Shinoda, K., yamashita, K., Yamasaki, R., Hashiguchi, A., Takashima, H. & Kira, J-I., Oct 1 2017, In : Neuromuscular Disorders. 27, 10, p. 959-961 3 p.

Research output: Contribution to journalArticle

Cranial Nerves
Muscle Weakness
Scoliosis
Bilateral Hearing Loss
Facial Muscles
5 Citations (Scopus)

Apomorphine Therapy for Neuronal Insulin Resistance in a Mouse Model of Alzheimer's Disease

Nakamura, N., Ohyagi, Y., Imamura, T., Yanagihara, Y. T., Iinuma, K. M., Soejima, N., Murai, H., Yamasaki, R. & Kira, J-I., Jan 1 2017, In : Journal of Alzheimer's Disease. 58, 4, p. 1151-1161 11 p.

Research output: Contribution to journalArticle

Apomorphine
Insulin Resistance
Alzheimer Disease
Insulysin
Brain
3 Citations (Scopus)

Cerebral blood flow laterality derived from arterial spin labeling as a biomarker for assessing the disease severity of parkinson's disease

Yamashita, K., Akio, H., Togao, O., kikuchi, K., yamaguchi, H., Suzuki, Y., Kamei, R., Yamasaki, R., Kira, J-I. & Honda, H., Jun 1 2017, In : Journal of Magnetic Resonance Imaging. 45, 6, p. 1821-1826 6 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Parkinson Disease
Biomarkers
Caudate Nucleus
Globus Pallidus
1 Citation (Scopus)

Clinical characteristics of atrial fibrillation-related cardioembolic stroke in patients aged 80 years or older

Tanaka, K., Yamada, T., Torii, T., Matsumoto, S., Yoshimura, T., Takase, K. I., Wakata, Y., Nakashima, N., Kira, J. I. & Murai, H., May 2017, In : Geriatrics and Gerontology International. 17, 5, p. 708-713 6 p.

Research output: Contribution to journalArticle

stroke
Atrial Fibrillation
Stroke
mortality
Mortality
Amyotrophic Lateral Sclerosis
Neuroglia
Motor Neurons
Spinal Cord
Microglia
3 Citations (Scopus)
Amyotrophic Lateral Sclerosis
Neuroglia
Motor Neurons
Spinal Cord
Microglia