• 1459 Citations
  • 22 h-Index
19972020

Research output per year

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Research Output

  • 1459 Citations
  • 22 h-Index
  • 32 Article
  • 6 Chapter
  • 4 Review article
  • 1 Letter
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Article
2020

Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway

Dubreuil, M. M., Morgens, D. W., Okumoto, K., Honsho, M., Contrepois, K., Lee-McMullen, B., Traber, G. M. A., Sood, R. S., Dixon, S. J., Snyder, M. P., Fujiki, Y. & Bassik, M. C., Feb 4 2020, In : Cell Reports. 30, 5, p. 1417-1433.e7

Research output: Contribution to journalArticle

Open Access
2019

A newly identified mutation in the PEX26 gene is associated with a milder form of Zellweger spectrum disorder

Tanaka, A. J., Okumoto, K., Tamura, S., Abe, Y., Hirsch, Y., Deng, L., Ekstein, J., Chung, W. K. & Fujiki, Y., Jan 1 2019, In : Cold Spring Harbor Molecular Case Studies. 5, 1, a003483.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

A newly isolated Pex7-binding, atypical PTS2 protein P7BP2 is a novel dynein-type AAA+ protein

Niwa, H., Miyauchi-Nanri, Y., Okumoto, K., Mukai, S., Noi, K., Ogura, T. & Fujiki, Y., Dec 1 2018, In : Journal of Biochemistry. 164, 6, p. 437-447 11 p.

Research output: Contribution to journalArticle

New splicing variants of mitochondrial Rho GTPase-1 (Miro1) transport peroxisomes

Okumoto, K., Ono, T., Toyama, R., Shimomura, A., Nagata, A. & Fujiki, Y., Feb 1 2018, In : Journal of Cell Biology. 217, 2, p. 619-633 15 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Onsite GTP fuelling via DYNAMO1 drives division of mitochondria and peroxisomes

Imoto, Y., Abe, Y., Honsho, M., Okumoto, K., Ohnuma, M., Kuroiwa, H., Kuroiwa, T. & Fujiki, Y., Dec 1 2018, In : Nature communications. 9, 1, 4634.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2017

BAK regulates catalase release from peroxisomes

Fujiki, Y., Miyata, N., Mukai, S., Okumoto, K. & Cheng, E. H., Mar 17 2017, In : Molecular & Cellular Oncology . 4, 3, e1306610.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Defining the dynamin-based ring organizing center on the peroxisome-dividing machinery isolated from Cyanidioschyzon merolae

Imoto, Y., Abe, Y., Okumoto, K., Honsho, M., Kuroiwa, H., Kuroiwa, T. & Fujiki, Y., Jan 1 2017, In : Journal of cell science. 130, 5, p. 853-867 15 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Localization of protein kinase NDR2 to peroxisomes and its role in ciliogenesis

Abe, S., Nagai, T., Masukawa, M., Okumoto, K., Homma, Y., Fujiki, Y. & Mizuno, K., Mar 10 2017, In : Journal of Biological Chemistry. 292, 10, p. 4089-4098 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The VDAC2-BAK axis regulates peroxisomal membrane permeability

Hosoi, K., Miyata, N., Mukai, S., Furuki, S., Okumoto, K., Cheng, E. H. & Fujiki, Y., Mar 6 2017, In : Journal of Cell Biology. 216, 3, p. 709-722

Research output: Contribution to journalArticle

22 Citations (Scopus)
2014

Distinct modes of ubiquitination of peroxisome-targeting signal type 1 (PTS1) receptor Pex5p regulate PTS1 protein import

Okumoto, K., Noda, H. & Fujiki, Y., May 16 2014, In : Journal of Biological Chemistry. 289, 20, p. 14089-14108 20 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2013

Pex5p stabilizes Pex14p: A study using a newly isolated pex5 CHO cell mutant, ZPEG101

Natsuyama, R., Okumoto, K. & Fujiki, Y., Jan 1 2013, In : Biochemical Journal. 449, 1, p. 195-207 13 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

System to quantify the import of peroxisomal matrix proteins by fluorescence intensity

Noguchi, M., Okumoto, K. & Fujiki, Y., Jun 1 2013, In : Genes to Cells. 18, 6, p. 476-492 17 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2012

AWP1/ZFAND6 functions in Pex5 export by interacting with cys-monoubiquitinated Pex5 and Pex6 AAA ATPase

Miyata, N., Okumoto, K., Mukai, S., Noguchi, M. & Fujiki, Y., Jan 1 2012, In : Traffic. 13, 1, p. 168-183 16 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
2011

Cysteine ubiquitination of PTS1 receptor Pex5p regulates Pex5p recycling

Okumoto, K., Misono, S., Miyata, N., Matsumoto, Y., Mukai, S. & Fujiki, Y., Aug 1 2011, In : Traffic. 12, 8, p. 1067-1083 17 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)
36 Citations (Scopus)
2003

CDNA cloning and characterization of the third isoform of human peroxin Pex11p

Tanaka, A., Okumoto, K. & Fujiki, Y., Jan 24 2003, In : Biochemical and Biophysical Research Communications. 300, 4, p. 819-823 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2000
91 Citations (Scopus)

Peroxisome Biogenesis and Molecular Defects in Peroxisome Assembly Disorders

Fujiki, Y., Okumoto, K., Otera, H. & Tamura, S., Jan 1 2000, In : Cell Biochemistry and Biophysics. 32, p. 155-164 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The peroxin Pex3p initiates membrane assembly in peroxisome biogenesis

Ghaedi, K., Tamura, S., Okumoto, K., Matsuzono, Y. & Fujiki, Y., Jun 2000, In : Molecular biology of the cell. 11, 6, p. 2085-2102 18 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)
1999

Isolation and characterization of novel peroxisome biogenesis-defective chinese hamster ovary cell mutants using green fluorescent-protein

Ghaedi, K., Kawai, A., Okumoto, K., Tamura, S., Shimozawa, N., Suzuki, Y., Kondo, N. & Fujiki, Y., May 1 1999, In : Experimental Cell Research. 248, 2, p. 489-497 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

The peroxin Pex14p: cDNA cloning by functional complementation on a Chinese hamster ovary cell mutant, characterization, and functional analysis

Shimizu, N., Itoh, R., Hirono, Y., Otera, H., Ghaedi, K., Tateishi, K., Tamura, S., Okumoto, K., Harano, T., Mukai, S. & Fujiki, Y., Apr 30 1999, In : Journal of Biological Chemistry. 274, 18, p. 12593-12604 12 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)
1998

Clofibrate-inducible, 28-kDa peroxisomal integral membrane protein is encoded by PEX11

Abe, I., Okumoto, K., Tamura, S. & Fujiki, Y., Jul 24 1998, In : FEBS Letters. 431, 3, p. 468-472 5 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Human PEX1 cloned by functional complementation on a CHO cell mutant is responsible for peroxisome-deficient Zellweger syndrome of complementation group I

Tamura, S., Okumoto, K., Toyama, R., Shimozawa, N., Tsukamoto, T., Suzuki, Y., Osumi, T., Kondo, N. & Fujiki, Y., Apr 14 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 8, p. 4350-4355 6 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Mutations in PEX10 is the cause of Zellweger peroxisome deficiency syndrome of complementation group B

Okumoto, K., Itoh, R., Shimozawa, N., Suzuki, Y., Tamura, S., Kondo, N. & Fujiki, Y., Sep 1 1998, In : Human Molecular Genetics. 7, 9, p. 1399-1405 7 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

Newly identified Chinese hamster ovary cell mutants are defective in biogenesis of peroxisomal membrane vesicles (peroxisomal ghosts), representing a novel complementation group in mammals

Kinoshita, N., Ghaedi, K., Shimozawa, N., Wanders, R. J. A., Matsuzono, Y., Imanaka, T., Okumoto, K., Suzuki, Y., Kondo, N. & Fujiki, Y., Sep 11 1998, In : Journal of Biological Chemistry. 273, 37, p. 24122-24130 9 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Peroxisome biogenesis disorders: Identification of a new complementation group distinct from peroxisome-deficient CHO mutants and not complemented by human PEX 13

Shimozawa, N., Suzuki, Y., Zhang, Z., Imamura, A., Tsukamoto, T., Osumi, T., Tateishi, K., Okumoto, K., Fujiki, Y., Orii, T., Barth, P. G., Wanders, R. J. A. & Kondo, N., Feb 13 1998, In : Biochemical and Biophysical Research Communications. 243, 2, p. 368-371 4 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: Studies with PEX5-defective CHO cell mutants

Otera, H., Okumoto, K., Tateishi, K., Ikoma, Y., Matsuda, E., Nishimura, M., Tsukamoto, T., Osumi, T., Ohashi, K., Higuchi, O. & Fujiki, Y., Jan 1 1998, In : Molecular and cellular biology. 18, 1, p. 388-399 12 p.

Research output: Contribution to journalArticle

154 Citations (Scopus)

PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of Pex12p

Okumoto, K., Shimozawa, N., Kawai, A., Tamura, S., Tsukamoto, T., Osumi, T., Moser, H., Wanders, R. J. A., Suzuki, Y., Kondo, N. & Fujiki, Y., Jul 1998, In : Molecular and cellular biology. 18, 7, p. 4324-4336 13 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)
1997

Isolation and characterization of peroxisome-deficient Chinese hamster ovary cell mutants representing human complementation group III

Okumoto, K., Bogaki, A., Tateishi, K., Tsukamoto, T., Osumi, T., Shimozawa, N., Suzuki, Y., Orii, T. & Fujiki, Y., May 25 1997, In : Experimental Cell Research. 233, 1, p. 11-20 10 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Isolation of a new peroxisome-deficient CHO cell mutant defective in peroxisome targeting signal-1 receptor

Tsukamoto, T., Bogaki, A., Okumoto, K., Tateishi, K., Fujiki, Y., Shimozawa, N., Suzuki, Y., Kondo, N. & Osumi, T., Jan 13 1997, In : Biochemical and Biophysical Research Communications. 230, 2, p. 402-406 5 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Newly identified Chinese hamster ovary cell mutants defective in peroxisome biogenesis represent two novel complementation groups in mammals

Tateishi, K., Okumoto, K., Shimozawa, N., Tsukamoto, T., Osumi, T., Suzuki, Y., Kondo, N., Okano, I. & Fujiki, Y., Jan 1 1997, In : European Journal of Cell Biology. 73, 4, p. 352-359 8 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)