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Fingerprint Dive into the research topics where Keisuke Tomohara is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 9 Similar Profiles
Hydantoins Chemical Compounds
Dimethyl Sulfoxide Chemical Compounds
Carbon Chemical Compounds
Assays Chemical Compounds
Plant Extracts Medicine & Life Sciences
Hyaluronoglucosaminidase Chemical Compounds
Amino Acids Chemical Compounds
Cyclic Ethers Chemical Compounds

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Research Output 2012 2020

  • 104 Citations
  • 5 h-Index
  • 11 Article

Early identification of promiscuous attributes of aldose reductase inhibitors using a DMSO-perturbation assay

Tomohara, K., Hasegawa, N., Adachi, I., Horino, Y. & Nose, T., Jan 15 2020, In : Bioorganic and Medicinal Chemistry Letters. 30, 2, 126815.

Research output: Contribution to journalArticle

Aldehyde Reductase
Dimethyl Sulfoxide
Assays
Detergents
Hydantoins
1 Citation (Scopus)

DMSO-Perturbing Assay for Identifying Promiscuous Enzyme Inhibitors

Tomohara, K., Adachi, I., Horino, Y., Kesamaru, H., Abe, H., Suyama, K. & Nose, T., Jan 1 2019, In : ACS Medicinal Chemistry Letters. 10, 6, p. 923-928 6 p.

Research output: Contribution to journalArticle

Enzyme Inhibitors
Dimethyl Sulfoxide
Assays
Enzymes
Conformations
3 Citations (Scopus)

Controllable Stereoselective Synthesis of (Z)- and (E)-Homoallylic Alcohols Using a Palladium-Catalyzed Three-Component Reaction

Horino, Y., Sugata, M., Mutsuura, I., Tomohara, K. & Abe, H., Nov 3 2017, In : Organic letters. 19, 21, p. 5968-5971 4 p.

Research output: Contribution to journalArticle

Palladium
palladium
alcohols
Alcohols
aldehydes
4 Citations (Scopus)

Discovery of hyaluronidase inhibitors from natural products and their mechanistic characterization under DMSO-perturbed assay conditions

Tomohara, K., Ito, T., Onikata, S., Kato, A. & Adachi, I., Jan 1 2017, In : Bioorganic and Medicinal Chemistry Letters. 27, 7, p. 1620-1623 4 p.

Research output: Contribution to journalArticle

Hyaluronoglucosaminidase
Catechin
Dimethyl Sulfoxide
Biological Products
Assays
5 Citations (Scopus)

Multiple production of α,α-disubstituted amino acid derivatives through direct chemical derivatization of natural plant extracts: An apparently difficult but successful route

Tomohara, K., Ito, T., Furusawa, K., Hasegawa, N., Tsuge, K., Kato, A. & Adachi, I., Jan 1 2017, In : Tetrahedron Letters. 58, 32, p. 3143-3147 5 p.

Research output: Contribution to journalArticle

Paeonia
Hydantoins
Ginger
Carbamates
Plant Extracts