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Research Output 1987 2020

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4 Citations (Scopus)

4D ASL-based MR angiography for visualization of distal arteries and leptomeningeal collateral vessels in moyamoya disease: a comparison of techniques

Togao, O., Hiwatashi, A., Obara, M., Yamashita, K., Momosaka, D., Nishimura, A., Arimura, K., Hata, N., Yoshimoto, K., Iihara, K., Van Cauteren, M. & Honda, H., Nov 1 2018, In : European Radiology. 28, 11, p. 4871-4881 11 p.

Research output: Contribution to journalArticle

Moyamoya Disease
Angiography
Arteries
Digital Subtraction Angiography
Cerebral Arteries

A case of concurrent schwannoma and meningioma at the same cervical level

Karashima, S., Arimura, K., Hashiguchi, K., Akagi, Y., Mukae, N., Nishimura, A., Kuga, D., Yoshimoto, K., Sayama, T., Suzuki, S. O. & Iihara, K., Jan 1 2017, In : Japanese Journal of Neurosurgery. 26, 10, p. 750-756 7 p.

Research output: Contribution to journalArticle

Neurilemmoma
Meningioma
Neurofibromatosis 2
Neoplasms

A case of diffuse midline glioma, H3 K27M mutant mimicking a hemispheric malignant glioma in an elderly patient

Fujioka, Y., Hata, N., Hatae, R., Suzuki, S. O., Sangatsuda, Y., Nakahara, Y., Mizoguchi, M. & Iihara, K., Feb 1 2020, In : Neuropathology. 40, 1, p. 99-103 5 p.

Research output: Contribution to journalArticle

Glioma
temozolomide
Molecular Pathology
Thalamus
Hippocampus
1 Citation (Scopus)
Epidermal Cyst
Differential Diagnosis
Arachnoid Cysts
Chordoma
Dermoid Cyst

Acceleration-selective arterial spin labeling MR angiography for visualization of brain arteriovenous malformations

Togao, O., Hiwatashi, A., Yamashita, K., Momosaka, D., Obara, M., Nishimura, A., Arimura, K., Hata, N., Iihara, K., Van Cauteren, M. & Honda, H., Sep 1 2019, In : Neuroradiology. 61, 9, p. 979-989 11 p.

Research output: Contribution to journalArticle

Arteriovenous Malformations
Angiography
Digital Subtraction Angiography
Brain
Drainage
6 Citations (Scopus)

Acceleration-selective arterial spin-labeling MR angiography used to visualize distal cerebral arteries and collateral vessels in moyamoya disease

Togao, O., Hiwatashi, A., Obara, M., Yamashita, K., Kikuchi, K., Kamei, R., Nishimura, A., Arimura, K., Yoshimoto, K., Iihara, K., Cauteren, M. V. & Honda, H., Feb 2018, In : Radiology. 286, 2, p. 611-621 11 p.

Research output: Contribution to journalArticle

Moyamoya Disease
Cerebral Arteries
Magnetic Resonance Angiography
Angiography
Internal Carotid Artery
1 Citation (Scopus)

A comparison of the prevalence and risk factors of complications in intracranial tumor embolization between the Japanese Registry of NeuroEndovascular Therapy 2 (JR-NET2) and JR-NET3

on behalf of the JR-NET2 and JR-NET3 study groups, Aug 1 2019, In : Acta Neurochirurgica. 161, 8, p. 1675-1682 8 p.

Research output: Contribution to journalArticle

Registries
External Carotid Artery
Neoplasms
Therapeutics
Odds Ratio
14 Citations (Scopus)

A comprehensive analysis identifies BRAF hotspot mutations associated with gliomas with peculiar epithelial morphology

Hatae, R., Hata, N., Suzuki, S. O., Yoshimoto, K., Kuga, D., Murata, H., Akagi, Y., Sangatsuda, Y., Iwaki, T., Mizoguchi, M. & Iihara, K., Jun 2017, In : Neuropathology. 37, 3, p. 191-199 9 p.

Research output: Contribution to journalArticle

Glioma
Mutation
Glioblastoma
Ganglioglioma
Neuroepithelial Neoplasms
3 Citations (Scopus)
Glioblastoma
Survival
temozolomide
Radiotherapy
Survival Rate
569 Citations (Scopus)

A Key Role for TRPM7 Channels in Anoxic Neuronal Death

Aarts, M., Iihara, K., Wei, W. L., Xiong, Z. G., Arundine, M., Cerwinski, W., MacDonald, J. F. & Tymianski, M., Dec 26 2003, In : Cell. 115, 7, p. 863-877 15 p.

Research output: Contribution to journalArticle

Reactive Nitrogen Species
Neurons
Oxygen
Reactive Oxygen Species
Nitrogen
36 Citations (Scopus)

Alogliptin, a dipeptidylpeptidase-4 inhibitor, for patients with diabetes mellitus type 2, induces tolerance to focal cerebral ischemia in non-diabetic, normal mice

Yang, D., Nakajo, Y., Iihara, K., Kataoka, H. & Yanamoto, H., Jun 23 2013, In : Brain Research. 1517, p. 104-113 10 p.

Research output: Contribution to journalArticle

Benzoates
Brain Ischemia
Type 2 Diabetes Mellitus
Glucagon-Like Peptide 1
Ischemia
48 Citations (Scopus)

Altered expression balance of matrix metalloproteinases and their inhibitors in human carotid plaque disruption: Results of quantitative tissue analysis using real-time RT-PCR method

Higashikata, T., Yamagishi, M., Higashi, T., Nagata, I., Iihara, K., Miyamoto, S., Ishibashi-Ueda, H., Nagaya, N., Iwase, T., Tomoike, H. & Sakamoto, A., Mar 1 2006, In : Atherosclerosis. 185, 1, p. 165-172 8 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-1
Matrix Metalloproteinase Inhibitors
Reverse Transcription
Matrix Metalloproteinase 9
Matrix Metalloproteinase 1

Analysis of expression and secretion of PDGF-B chain o£ cultured aortic endothelial cell of stroke-prone SHR

Iihara, K., Sesahara, M., Saeki, Y., Hashimoto, N., Kikuchi, H. & Hazama, F., Jan 1 1993, In : japanese heart journal. 34, 4, 1 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

ANALYSIS OF SECRETION AND EXPRESSION OF PLATELET‐DERIVED GROWTH FACTOR IN CULTURED ENDOTHELIAL CELLS FROM STROKE‐PRONE SPONTANEOUSLY HYPERTENSIVE RAT

Iihara, K., Sasahara, M., Saeki, Y., Hashimoto, N., Kikuchi, H. & Hazama, F., 1993, In : Clinical and Experimental Pharmacology and Physiology. 20, 7-8, p. 515-521 7 p.

Research output: Contribution to journalArticle

Endothelial Growth Factors
Inbred SHR Rats
Proto-Oncogene Proteins c-sis
Cultured Cells
Intercellular Signaling Peptides and Proteins

Analysis of the risk of ischemic stroke in intracranial atherosclerotic stenosis by CBF measurement and plaque characterization

Egashira, Y., Iihara, K., Satow, T., Takahashi, J., Yamada, N. & Miyamoto, S., Jan 1 2009, In : Japanese Journal of Neurosurgery. 18, 7, p. 502-508 7 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Pathologic Constriction
Stroke
Carotid Stenosis
Single-Photon Emission-Computed Tomography
4 Citations (Scopus)

A nationwide survey on pregnancy and delivery management in association with moyamoya disease

Takahashi, J. C., Ikeda, T., Iihara, K. & Miyamoto, S., Jan 1 2009, In : Japanese Journal of Neurosurgery. 18, 5, p. 367-375 9 p.

Research output: Contribution to journalArticle

Moyamoya Disease
Pregnancy
Cerebral Infarction
Cerebral Hemorrhage
Patient Compliance
Astrocytoma
Glioma
Hemorrhage
Neoplasms
Neuroglia
8 Citations (Scopus)

An integrated stroke model with a consistent penumbra for the assessment of neuroprotective interventions

Yang, D., Nakajo, Y., Iihara, K., Kataoka, H., Nakagawara, J., Zhao, Q. & Yanamoto, H., Feb 28 2014, In : European Neurology. 71, 1-2, p. 4-18 15 p.

Research output: Contribution to journalArticle

Stroke
Zygoma
Ischemia
Mortality
Fascia
4 Citations (Scopus)

Arterial spin-labeling is useful for the diagnosis of residual or recurrent meningiomas

Kikuchi, K., Hiwatashi, A., Togao, O., Yamashita, K., Kamei, R., Yoshimoto, K., Iihara, K., Suzuki, S. O., Iwaki, T., Suzuki, Y. & Honda, H., Oct 1 2018, In : European Radiology. 28, 10, p. 4334-4342 9 p.

Research output: Contribution to journalArticle

Meningioma
Radiology
ROC Curve
Reading
Neoplasms
36 Citations (Scopus)

Aspergillosis of the central nervous system causing subarachnoid hemorrhage from mycotic aneurysm of the basilar artery. Case report

Iihara, K., Makita, Y., Nabeshima, S., Tei, T., Keyaki, A. & Nioka, H., Jan 1 1990, In : Neurologia medico-chirurgica. 30, 8, p. 618-623 6 p.

Research output: Contribution to journalArticle

Infected Aneurysm
Basilar Artery
Aspergillosis
X Ray Computed Tomography
Cerebral Infarction
28 Citations (Scopus)

Assessment of necrotic core with intraplaque hemorrhage in atherosclerotic carotid artery plaque by MR imaging with 3D gradient-echo sequence in patients with high-grade stenosis: Clinical article

Hishikawa, T., Iihara, K., Yamada, N., Ishibashi-Ueda, H. & Miyamoto, S., Oct 2010, In : Journal of Neurosurgery. 113, 4, p. 890-896 7 p.

Research output: Contribution to journalArticle

Carotid Stenosis
Pathologic Constriction
Hemorrhage
Glycophorin
Carotid Endarterectomy
103 Citations (Scopus)

Association between signal hyperintensity on T1-weighted MR imaging of carotid plaques and ipsilateral ischemic events

Yamada, N., Higashi, M., Otsubo, R., Sakuma, T., Oyama, N., Tanaka, R., Iihara, K., Naritomi, H., Minematsu, K. & Naito, H., Feb 1 2007, In : American Journal of Neuroradiology. 28, 2, p. 287-292 6 p.

Research output: Contribution to journalArticle

Pathologic Constriction
Arteries
Carotid Stenosis
Carotid Arteries
Clinical Trials
1 Citation (Scopus)

Bony and Cartilaginous Tissues in Lumbosacral Lipomas

Shimogawa, T., Morioka, T., Murakami, N., Mukae, N., Hashiguchi, K., Suzuki, S. O. & Iihara, K., Sep 1 2018, In : Pediatric Neurosurgery. 53, 5, p. 305-310 6 p.

Research output: Contribution to journalArticle

Lipoma
Neurulation
Hyaline Cartilage
Spine
Bone Marrow
1 Citation (Scopus)
Carotid Stenosis
Carotid Arteries
Radiation
Vertebrobasilar Insufficiency
Common Carotid Artery
1 Citation (Scopus)
Carotid Stenosis
Carotid Arteries
Radiation
Vertebrobasilar Insufficiency
Common Carotid Artery
1 Citation (Scopus)
Carotid Stenosis
Carotid Arteries
Radiation
Vertebrobasilar Insufficiency
Common Carotid Artery
1 Citation (Scopus)

Carotid artery stenting for radiation-induced carotid stenosis

Egashira, Y., Satow, T., Masuda, K., Okawa, M., Ohnishi, H., Okazaki, T., Takahashi, J. C., Murao, K. I., Iihara, K. & Miyamoto, S., Oct 1 2010, In : Neurological Surgery. 38, 10, p. 913-920 8 p.

Research output: Contribution to journalArticle

Carotid Stenosis
Carotid Arteries
Radiation
Vertebrobasilar Insufficiency
Common Carotid Artery

Carotid endarterectomy(CEA): Basic procedure and variations

Nishimura, A. & Iihara, K., Jan 1 2017, In : Japanese Journal of Neurosurgery. 26, 10, p. 738-744 7 p.

Research output: Contribution to journalArticle

Carotid Endarterectomy
Carotid Stenosis
Internal Carotid Artery
Radiation
39 Citations (Scopus)

Cerebral blood flow and metabolism of hyperperfusion after cerebral revascularization in patients with moyamoya disease

Kaku, Y., Iihara, K., Nakajima, N., Kataoka, H., Fukuda, K., Masuoka, J., Fukushima, K., Iida, H. & Hashimoto, N., Nov 1 2012, In : Journal of Cerebral Blood Flow and Metabolism. 32, 11, p. 2066-2075 10 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Cerebral Revascularization
Moyamoya Disease
Positron-Emission Tomography
Oxygen

Changing paradigms of periprocedural antithrombotic therapy in neuroendovascular therapy: Analysis of JR-NET 3

Japanese Registry of Neuroendovascular Therapy (JR-NET) investigators, Jan 1 2019, In : Neurologia medico-chirurgica. 59, 7, p. 247-256 10 p.

Research output: Contribution to journalArticle

Open Access
Registries
Therapeutics
Anticoagulants
Japan

Characteristics of cerebral aneurysms in Japan

Ikawa, F., Hidaka, T., Yoshiyama, M., Ohba, H., Matsuda, S., Ozono, I., Iihara, K., Kinouchi, H., Nozaki, K., Kato, Y., Morita, A., Michihata, N., Yasunaga, H. & Kurisu, K., Jan 1 2019, In : Neurologia medico-chirurgica. 59, 11, p. 399-406 8 p.

Research output: Contribution to journalArticle

Open Access
Intracranial Aneurysm
Japan
Subarachnoid Hemorrhage
Rupture
Incidence
2 Citations (Scopus)

Clinical analysis of 270 cases of microsurgical lumbar discectomy

Hanakita, J., Suwa, H., Nishihara, K., Iihara, K., Sakaida, H. & Nishi, S., Jan 1 1991, In : Neurological Surgery. 19, 5, p. 429-434 6 p.

Research output: Contribution to journalArticle

Lumbosacral Region
Diskectomy
Intervertebral Disc Displacement
Microsurgery
Intervertebral Disc

Clinical characteristics and endovascular treatment for spinal dural arteriovenous fistula in Japan: Japanese registry of neuroendovascular therapy 2 and 3

Tsuruta, W., Matsumaru, Y., Iihara, K., Satow, T., Sakai, N., Katsumata, M., Hosoo, H., Sato, M., Ito, Y., Marushima, A., Hayakawa, M., Ishikawa, E. & Matsumura, A., Jan 1 2019, In : Neurologia medico-chirurgica. 59, 12, p. 492-497 6 p.

Research output: Contribution to journalArticle

Open Access
Central Nervous System Vascular Malformations
Registries
Japan
Therapeutics
Incidence
1 Citation (Scopus)

Clinical Characteristics of Transient Ischemic Attack Patients with Atrial Fibrillation: Analyses of a Multicenter Retrospective Study

Hama, Y., Uehara, T., Ohara, T., Kimura, K., Okada, Y., Hasegawa, Y., Tanahashi, N., Suzuki, A., Takagi, S., Nakagawara, J., Arii, K., Nagahiro, S., Ogasawara, K., Nagao, T., Uchiyama, S., Matsumoto, M., Iihara, K., Toyoda, K. & Minematsu, K., May 1 2015, In : Cerebrovascular diseases extra. 5, 2, p. 84-90 7 p.

Research output: Contribution to journalArticle

Transient Ischemic Attack
Atrial Fibrillation
Multicenter Studies
Retrospective Studies
Odds Ratio

Clinical experience with recently produced devices for use in spinal surgery

Hanakita, J., Suwa, H., Iihara, K., Mizuno, M., Namura, S., Shibata, O. & Otsuka, T., 1992, In : Neurological Surgery. 20, 3, p. 243-248 6 p.

Research output: Contribution to journalArticle

Orthopedic Fixation Devices
Bone Screws
Spinal Fusion
Surgical Instruments
Spine
19 Citations (Scopus)

Clinical features of intradural neurinomas in the cauda equina and around the conus medullaris

Hanakita, J., Suwa, H., Nagayasu, S., Nishi, S., Iihara, K. & Sakaida, H., Jan 1 1992, In : Neurochirurgia. 35, 5, p. 145-149 5 p.

Research output: Contribution to journalArticle

Cauda Equina
Neurilemmoma
Spinal Cord
Neoplasms
Spontaneous Remission
19 Citations (Scopus)

Clinical implications of the cortical hyperintensity belt sign in fluid-attenuated inversion recovery images after bypass surgery for moyamoya disease

Hamano, E., Kataoka, H., Morita, N., Maruyama, D., Satow, T., Iihara, K. & Takahashi, J. C., Jan 2017, In : Journal of Neurosurgery. 126, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Moyamoya Disease
Regional Blood Flow
Middle Cerebral Artery
Infarction
7 Citations (Scopus)

Clinical significance of PD-L1 expression in brain metastases from non-small cell lung cancer

Takamori, S., Toyokawa, G., Okamoto, I., Takada, K., Kinoshita, F., Kozuma, Y., Matsubara, T., Haratake, N., Akamine, T., Mukae, N., Hirai, F., Tagawa, T., Oda, Y., Iwaki, T., Iihara, K., Nakanishi, Y. & Maehara, Y., Jan 2018, In : Anticancer research. 38, 1, p. 553-557 5 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cell Death
Neoplasm Metastasis
Ligands
Brain
1 Citation (Scopus)

Clinical Significance of Prenatal and Postnatal Heavily T2-Weighted Magnetic Resonance Images in Patients with Myelomeningocele

Hashiguchi, K., Morioka, T., Murakami, N., Yamashita, K., Hiwatashi, A., Ochiai, M., Morokuma, S. & Iihara, K., Nov 1 2015, In : Pediatric Neurosurgery. 50, 6, p. 310-320 11 p.

Research output: Contribution to journalArticle

Meningomyelocele
Magnetic Resonance Spectroscopy
Rhombencephalon
Magnetic Resonance Imaging
Anatomy
13 Citations (Scopus)

Clinical validity of cerebral oxygen saturation measured by time-resolved spectroscopy during carotid endarterectomy

Yoshitani, K., Kuwajima, K., Irie, T., Inatomi, Y., Miyazaki, A., Iihara, K. & Ohnishi, Y., Jul 2013, In : Journal of Neurosurgical Anesthesiology. 25, 3, p. 248-253 6 p.

Research output: Contribution to journalArticle

Carotid Endarterectomy
Spectrum Analysis
Oxygen
Carotid Arteries
Constriction
27 Citations (Scopus)

Cobb syndrome in an infant: Treatment with endovascular embolization and corticosteroid therapy: Case report

Soeda, A., Sakai, N., Iihara, K., Nagata, I., Humphreys, R. P., McComb, J. G., Higashida, R. T. & Chapman, P. H., Mar 1 2003, In : Neurosurgery. 52, 3, p. 711-715 5 p.

Research output: Contribution to journalArticle

Adrenal Cortex Hormones
Hemangioma
Therapeutics
Enbucrilate
Paraparesis
7 Citations (Scopus)

Cognitive dysfunction survey of the japanese patients with moyamoya disease (Cosmo-japan study): Study protocol

COSMO-Japan Study Group, Feb 20 2015, In : Neurologia medico-chirurgica. 55, 3, p. 199-203 5 p.

Research output: Contribution to journalArticle

Moyamoya Disease
Japan
Cerebrovascular Disorders
Social Welfare
Brain Diseases
13 Citations (Scopus)

Comparing intracerebral hemorrhages associated with direct oral anticoagulants or warfarin

Kurogi, R., Nishimura, K., Nakai, M., Kada, A., Kamitani, S., Nakagawara, J., Toyoda, K., Ogasawara, K., Ono, J., Shiokawa, Y., Aruga, T., Miyachi, S., Nagata, I., Matsuda, S., Yoshimura, S., Okuchi, K., Suzuki, A., Nakamura, F., Onozuka, D., Ido, K. & 7 others, Kurogi, A., Mukae, N., Nishimura, A., Arimura, K., Kitazono, T., Hagihara, A. & Iihara, K., Mar 27 2018, In : Neurology. 90, 13, p. e1143-e1149

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Warfarin
Anticoagulants
Odds Ratio
Hematoma
1 Citation (Scopus)
Amaurosis Fugax
Transient Ischemic Attack
Hemianopsia
Registries
Diplopia
2 Citations (Scopus)
Open Access
end effectors
End effectors
strokes
Brain computer interface
recovery

Comprehensive stroke care capabilities in Japan: A neurovascular surgeon's perspective

Iihara, K., Aug 1 2015, In : Neurosurgery. 62, p. 107-116 10 p.

Research output: Contribution to journalArticle

Japan
Stroke
Surgeons
17 Citations (Scopus)

Consciousness level and off-hour admission affect discharge outcome of acute stroke patients: A J-ASPECT study

Kamitani, S., Nishimura, K., Nakamura, F., Kada, A., Nakagawara, J., Toyoda, K., Ogasawara, K., Ono, J., Shiokawa, Y., Aruga, T., Miyachi, S., Nagata, I., Matsuda, S., Miyamoto, Y., Iwata, M., Suzuki, A., Ishikawa, K. B., Kataoka, H., Morita, K., Kobayashi, Y. & 1 others, Iihara, K., Jan 1 2014, In : Journal of the American Heart Association. 3, 5, e001059.

Research output: Contribution to journalArticle

Consciousness
Stroke
Logistic Models
Patient Discharge
Cerebral Hemorrhage
Terminally Ill
Resuscitation
Japan
Living Wills
Euthanasia
79 Citations (Scopus)

Continued growth of and increased symptoms from a thrombosed giant aneurysm of the vertebral artery after complete endovascular occlusion and trapping: The role of vasa vasorum: Case report

Iihara, K., Murao, K., Sakai, N., Soeda, A., Ishibashi-Ueda, H., Yutani, C., Yamada, N. & Nagata, I., Feb 1 2003, In : Journal of Neurosurgery. 98, 2, p. 407-413 7 p.

Research output: Contribution to journalArticle

Vasa Vasorum
Vertebral Artery
Aneurysm
Thrombosis
Growth
Open Access
Temporal Lobe
Hippocampus
Stroke
Radiation
Epilepsy