Research Output per year
Research Output 2000 2018
- 1043 Citations
- 19 h-Index
- 41 Article
BubR1 insufficiency impairs angiogenesis in aging and in experimental critical limb ischemic mice
Okadome, J., Matsumoto, T., Yoshiya, K., Matsuda, D., Tamada, K., Onimaru, M., Nakano, K., Egashira, K., Yonemitsu, Y. & Maehara, Y., Aug 1 2018, In : Journal of Vascular Surgery. 68, 2, p. 576-586.e1Research output: Contribution to journal › Article
Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease
Murata, K., Motomura, Y., Tanaka, T., Kanno, S., Yano, T., Onimaru, M., Shimoyama, A., Nishio, H., Sakai, Y., Oh-Hora, M., Hara, H., Fukase, K., Takada, H., Masuda, S., Ohga, S., Yamasaki, S. & Hara, T., Oct 2017, In : Clinical and Experimental Immunology. 190, 1, p. 54-67 14 p.Research output: Contribution to journal › Article
Chd2 regulates chromatin for proper gene expression toward differentiation in mouse embryonic stem cells
Semba, Y., Harada, A., Maehara, K., Oki, S., Meno, C., Ueda, J., Yamagata, K., Suzuki, A., Onimaru, M., Nogami, J., Okada, S., Akashi, K. & Ohkawa, Y., Sep 1 2017, In : Nucleic acids research. 45, 15, p. 8758-8772 15 p.Research output: Contribution to journal › Article
Activation of Nod1 signaling induces fetal growth restriction and death through fetal and maternal vasculopathy
Inoue, H., Nishio, H., Takada, H., Sakai, Y., Nanishi, E., Ochiai, M., Onimaru, M., Chen, S. J., Matsui, T. & Hara, T., Mar 15 2016, In : Journal of Immunology. 196, 6, p. 2779-2787 9 p.Research output: Contribution to journal › Article
BubR1 Insufficiency Impairs Liver Regeneration in Aged Mice after Hepatectomy through Intercalated Disc Abnormality
Ikawa-Yoshida, A., Matsumoto, T., Okano, S., Aoyagi, Y., Matsubara, Y., Furuyama, T., Nakatsu, Y., Tsuzuki, T., Onimaru, M., Ohkusa, T., Nomura, M. & Maehara, Y., Aug 26 2016, In : Scientific reports. 6, 32399.Research output: Contribution to journal › Article
BUBR1 insufficiency in mice increases their sensitivity to oxidative stress
Matsuda, D., matsumoto, T., Honma, K., Ikawa-Yoshida, A., Onimaru, M., Furuyama, T., Nakatsu, Y., Tsuzuki, T. & Maehara, Y., Nov 1 2016, In : In Vivo. 30, 6, p. 769-776 8 p.Research output: Contribution to journal › Article
Peritoneal dissemination requires an Sp1-dependent CXCR4/CXCL12 signaling axis and extracellular matrix-directed spheroid formation
Kasagi, Y., Harada, Y., Morodomi, Y., Iwai, T., Saito, S., Yoshida, K., Oki, E., Saeki, H., Ohgaki, K., Sugiyama, M., Onimaru, M., Maehara, Y. & Yonemitsu, Y., Jan 15 2016, In : Cancer Research. 76, 2, p. 347-357 11 p.Research output: Contribution to journal › Article
Activation of an innate immune receptor, Nod1, accelerates atherogenesis in Apoe2/2 mice
Kanno, S., Nishio, H., Tanaka, T., Motomura, Y., Murata, K., Ihara, K., Onimaru, M., Yamasaki, S., Kono, H., Sueishi, K. & Hara, T., Jan 15 2015, In : Journal of Immunology. 194, 2, p. 773-780 8 p.Research output: Contribution to journal › Article
BubR1 insufficiency inhibits neointimal hyperplasia through impaired vascular smooth muscle cell proliferation in mice
Kyuragi, R., Matsumoto, T., Harada, Y., Saito, S., Onimaru, M., Nakatsu, Y., Tsuzuki, T., Nomura, M., Yonemitsu, Y. & Maehara, Y., Feb 2 2015, In : Arteriosclerosis, thrombosis, and vascular biology. 35, 2, p. 341-347 7 p.Research output: Contribution to journal › Article
Biological characterization and analysis of metastasis-related genes in cell lines derived from the primary lesion and lymph node metastasis of a squamous cell carcinoma arising in the mandibular gingiva
Fujinaga, T., Wataru, K., Sugiura, T., Kobayashi, Y., Ohyama, Y., Ikari, T., Onimaru, M., Akimoto, N., Jogo, R. & Mori, Y., Jan 1 2014, In : International journal of oncology. 44, 5, p. 1614-1624 11 p.Research output: Contribution to journal › Article
Effects of transforming growth factor beta 1 on the plasminogen activation system, collagen and integrin synthesis, and proliferation of rabbit mandibular condylar chondrocytes
Ishibashi, H., Nariai, Y., Kanno, T., Onimaru, M. & Sekine, J., Apr 1 2014, In : International Journal of Oral and Maxillofacial Surgery. 43, 4, p. 470-475 6 p.Research output: Contribution to journal › Article
Chronic kidney disease is associated with neovascularization and intraplaque hemorrhage in coronary atherosclerosis in elders: Results from the Hisayama Study
Nakano, T., Ninomiya, T., Sumiyoshi, S., Onimaru, M., Fujii, H., Itabe, H., Nakashima, Y., Sueishi, K., Tsuruya, K., Oda, Y., Kitazono, T. & Kiyohara, Y., Jan 1 2013, In : Kidney International. 84, 2, p. 373-380 8 p.Research output: Contribution to journal › Article
DVC1-0101 to treat peripheral arterial disease: A phase I/IIa open-label dose-escalation clinical trial
Yonemitsu, Y., matsumoto, T., Itoh, H., Okazaki, J., Uchiyama, M., Yoshida, K., Onimaru, M., Onohara, T., Inoguchi, H., Kyuragi, R., Shimokawa, M., Ban, H., Tanaka, M., Inoue, M., Shu, T., Hasegawa, M., Nakanishi, Y. & Maehara, Y., Jan 1 2013, In : Molecular Therapy. 21, 3, p. 707-714 8 p.Research output: Contribution to journal › Article
Ex vivo generation of highly purified and activated natural killer cells from human peripheral blood
Saito, S., Harada, Y., Morodomi, Y., Onimaru, M., Yoshida, K., Kyuragi, R., Matsubara, H. & Yonemitsu, Y., Aug 1 2013, In : Human Gene Therapy Methods. 24, 4, p. 241-252 12 p.Research output: Contribution to journal › Article
BioKnife, a uPA activity-dependent oncolytic sendai virus, eliminates pleural spread of malignant mesothelioma via simultaneous stimulation of uPA expression
Morodomi, Y., Yano, T., Kinoh, H., Harada, Y., Saito, S., Kyuragi, R., Yoshida, K., Onimaru, M., Shoji, F., Yoshida, T., Ito, K., Shikada, Y., Maruyama, R., Hasegawa, M., Maehara, Y. & Yonemitsu, Y., Jan 1 2012, In : Molecular Therapy. 20, 4, p. 769-777 9 p.Research output: Contribution to journal › Article
Endogenous cardiac troponin T modulates Ca2+-mediated smooth muscle contraction
Kajioka, S., Takahashi-Yanaga, F., Shahab, N., Onimaru, M., Matsuda, M., Takahashi, R., Asano, H., Morita, H., Morimoto, S., Yonemitsu, Y., Hayashi, M., Seki, N., Sasaguri, T., Hirata, M., Nakayama, S. & Naito, S., Dec 1 2012, In : Scientific reports. 2, 979.Research output: Contribution to journal › Article
Obstruction enhances rho-kinase pathway and diminishes protein kinase C pathway in carbachol-induced calcium sensitization in contraction of α-toxin permeabilized guinea pig detrusor smooth muscle
Shahab, N., Kajioka, S., Takahashi, F., Onimaru, M., Matsuda, M., Seki, N. & Naito, S., Apr 1 2012, In : Neurourology and Urodynamics. 31, 4, p. 593-599 7 p.Research output: Contribution to journal › Article
Transfection of hypoxia-inducible factor-1 decoy oligodeoxynucleotides suppresses expression of vascular endothelial growth factor in oral squamous cell carcinoma cells
Imai, M., Ishibashi, H., Nariai, Y., Kanno, T., Sekine, J., Onimaru, M. & Mori, Y., Oct 1 2012, In : Journal of Oral Pathology and Medicine. 41, 9, p. 675-681 7 p.Research output: Contribution to journal › Article
Angiogenic and lymphangiogenic cascades in the tumor microenvironment
Onimaru, M. & Yonemitsu, Y., Jan 1 2011, In : Frontiers in Bioscience - Scholar. 3 S, 1, p. 216-225 10 p.Research output: Contribution to journal › Article
Antagonism of VEGF by genetically engineered dendritic cells is essential to induce antitumor immunity against malignant ascites
Sugiyama, M., Kakeji, Y., Tsujitani, S., Harada, Y., Onimaru, M., Yoshida, K., Tanaka, S., Emi, Y., Morita, M., Morodomi, Y., Hasegawa, M., Maehara, Y. & Yonemitsu, Y., Mar 1 2011, In : Molecular Cancer Therapeutics. 10, 3, p. 540-549 10 p.Research output: Contribution to journal › Article
High podoplanin expression in cancer cells predicts lower incidence of nodal metastasis in patients with lung squamous cell carcinoma
Suzuki, H., Onimaru, M., Koga, T., Takeshita, M., Yano, T., Maehara, Y., Nakamura, S. & Sueishi, K., Feb 15 2011, In : Pathology Research and Practice. 207, 2, p. 111-115 5 p.Research output: Contribution to journal › Article
An autocrine linkage between matrix metalloproteinase-14 and tie-2 via ectodomain shedding modulates angiopoietin-1-dependent function in endothelial cells
Onimaru, M., Yonemitsu, Y., Suzuki, H., Fujii, T. & Sueishi, K., Apr 1 2010, In : Arteriosclerosis, thrombosis, and vascular biology. 30, 4, p. 818-826 9 p.Research output: Contribution to journal › Article
Podoplanin in cancer cells is experimentally able to attenuate prolymphangiogenic and lymphogenous metastatic potentials of lung squamoid cancer cells
Suzuki, H., Onimaru, M., Yonemitsu, Y., Maehara, Y., Nakamura, S. & Sueishi, K., Oct 31 2010, In : Molecular cancer. 9, 287.Research output: Contribution to journal › Article
Urokinase-targeted fusion by oncolytic sendai virus eradicates orthotopic glioblastomas by pronounced synergy with interferon-β gene
Hasegawa, Y., Kinoh, H., Iwadate, Y., Onimaru, M., Ueda, Y., Harada, Y., Saito, S., Furuya, A., Saegusa, T., Morodomi, Y., Hasegawa, M., Saito, S., Aoki, I., Saeki, N. & Yonemitsu, Y., Jan 1 2010, In : Molecular Therapy. 18, 10, p. 1778-1786 9 p.Research output: Contribution to journal › Article
Autocrine Loop between Vascular Endothelial Growth Factor (VEGF)-C and VEGF Receptor-3 Positively Regulates Tumor-Associated Lymphangiogenesis in Oral Squamoid Cancer Cells
Matsuura, M., Onimaru, M., Yonemitsu, Y., Suzuki, H., Nakano, T., Ishibashi, H., Shirasuna, K. & Sueishi, K., Jan 1 2009, In : American Journal of Pathology. 175, 4, p. 1709-1721 13 p.Research output: Contribution to journal › Article
VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGF-B
Onimaru, M., Yonemitsu, Y., Fujii, T., Tanii, M., Nakano, T., Nakagawa, K., Kohno, R. I., Hasegawa, M., Nishikawa, S. I. & Sueishi, K., Nov 1 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 297, 5, p. H1685-H1696Research output: Contribution to journal › Article
Inhibition of nuclear translocation of apoptosis-inducing factor is an essential mechanism of the neuroprotective activity of pigment epithelium-derived factor in a rat model of retinal degeneration
murakami, Y., Ikeda, Y., Yonemitsu, Y., Onimaru, M., Nakagawa, K., Kohno, R. I., Miyazaki, M., Hisatomi, T., Nakamura, M., Yabe, T., Hasegawa, M., Ishibashi, T. & Sueishi, K., Jan 1 2008, In : American Journal of Pathology. 173, 5, p. 1326-1338 13 p.Research output: Contribution to journal › Article
Statins restore ischemic limb blood flow in diabetic microangiopathy via eNOS/NO upregulation but not via PDGF-BB expression
Fujii, T., Onimaru, M., Yonemitsu, Y., Kuwano, H. & Sueishi, K., Jun 1 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 294, 6, p. H2785-H2791Research output: Contribution to journal › Article
VEGF function for upregulation of endogenous PlGF expression during FGF-2-mediated therapeutic angiogenesis
Fujii, T., Yonemitsu, Y., Onimaru, M., Inoue, M., Hasegawa, M., Kuwano, H. & Sueishi, K., Sep 1 2008, In : Atherosclerosis. 200, 1, p. 51-57 7 p.Research output: Contribution to journal › Article
A free radical scavenger but not FGF-2-mediated angiogenic therapy rescues myonephropathic metabolic syndrome in severe hindlimb ischemia
Kaneko, K., Yonemitsu, Y., Fujii, T., Onimaru, M., Jin, C. H., Inoue, M., Hasegawa, M., Onohara, T., Maehara, Y. & Sueishi, K., Apr 1 2006, In : American Journal of Physiology - Heart and Circulatory Physiology. 290, 4, p. H1484-H1492Research output: Contribution to journal › Article
Diabetic microangiopathy in ischemic limb is a disease of disturbance of the platelet-derived growth factor-BB/protein kinase C axis but not of impaired expression of angiogenic factors
Tanii, M., Yonemitsu, Y., Fujii, T., Shikada, Y., Kohno, R. I., Onimaru, M., Okano, S., Inoue, M., Hasegawa, M., Onohara, T., Maehara, Y. & Sueishi, K., Jan 1 2006, In : Circulation research. 98, 1, p. 55-62 8 p.Research output: Contribution to journal › Article
Induction of efficient antitumor immunity using dendritic cells activated by recombinant Sendai virus and its modulation by exogenous IFN-β gene
Shibata, S., Okano, S., Yonemitsu, Y., Onimaru, M., Sata, S., Nagata-Takeshita, H., Inoue, M., Zhu, T., Hasegawa, M., Moroi, Y., Furue, M. & Sueishi, K., Sep 15 2006, In : Journal of Immunology. 177, 6, p. 3564-3576 13 p.Research output: Contribution to journal › Article
Nonendothelial mesenchymal cell-derived MCP-1 is required for FGF-2-mediated therapeutic neovascularization: Critical role of the inflammatory/arteriogenic pathway
Fujii, T., Yonemitsu, Y., Onimaru, M., Tanii, M., Nakano, T., Egashira, K., Takehara, T., Inoue, M., Hasegawa, M., Kuwano, H. & Sueishi, K., Nov 1 2006, In : Arteriosclerosis, thrombosis, and vascular biology. 26, 11, p. 2483-2489 7 p.Research output: Contribution to journal › Article
The regulation of vascular endothelial growth factors (VEGF-A, -C, and -D) expression in the retinal pigment epithelium
Ikeda, Y., Yonemitsu, Y., Onimaru, M., Nakano, T., Miyazaki, M., Kohno, R. I., Nakagawa, K., Ueno, A., Sueishi, K. & Ishibashi, T., Nov 1 2006, In : Experimental Eye Research. 83, 5, p. 1031-1040 10 p.Research output: Contribution to journal › Article
Cytoplasmic expression and extracellular deposition of an antiangiogenic factor, pigment epithelium-derived factor, in human atherosclerotic plaques
Baba, H., Yonemitsu, Y., Nakano, T., Onimaru, M., Miyazaki, M., Ikeda, Y., Sumiyoshi, S., Ueda, Y., Hasegawa, M., Yoshino, I., Maehara, Y. & Sueishi, K., Sep 1 2005, In : Arteriosclerosis, thrombosis, and vascular biology. 25, 9, p. 1938-1944 7 p.Research output: Contribution to journal › Article
Platelet-derived growth factor-AA is an essential and autocrine regulator of vascular endothelial growth factor expression in non-small cell lung carcinomas
Shikada, Y., Yonemitsu, Y., Koga, T., Onimaru, M., Nakano, T., Okano, S., Sata, S., Nakagawa, K., Yoshino, I., Maehara, Y. & Sueishi, K., Aug 15 2005, In : Cancer Research. 65, 16, p. 7241-7248 8 p.Research output: Contribution to journal › Article
Essential role of PDGFRα-p70S6K signaling in mesenchymal cells during therapeutic and tumor angiogenesis in vivo role of PDGFRα during angiogenesis
Tsutsumi, N., Yonemitsu, Y., Shikada, Y., Onimaru, M., Tanii, M., Okano, S., Kaneko, K., Hasegawa, M., Hashizume, M., Maehara, Y. & Sueishi, K., May 14 2004, In : Circulation Research. 94, 9, p. 1186-1194 9 p.Research output: Contribution to journal › Article
Recombinant Sendai virus vectors for activated T lymphocytes
Okano, S., Yonemitsu, Y., Nagata, S., Sata, S., Onimaru, M., Nakagawa, K., Tomita, Y., Kishihara, K., Hashimoto, S., Nakashima, Y., Sugimachi, K., Hasegawa, M. & Sueishi, K., Aug 1 2003, In : Gene Therapy. 10, 16, p. 1381-1391 11 p.Research output: Contribution to journal › Article
Fibroblast growth factor-2 gene transfer can stimulate hepatocyte growth factor expression irrespective of hypoxia-mediated downregulation in ischemic limbs
Onimaru, M., Yonemitsu, Y., Tanii, M., Nakagawa, K., Masaki, I., Okano, S., Ishibashi, H., Shirasuna, K., Hasegawa, M. & Sueishi, K., Nov 15 2002, In : Circulation research. 91, 10, p. 923-930 8 p.Research output: Contribution to journal › Article
Hypoxia-induced angiogenesis of cultured human salivary gland carcinoma cells enhances vascular endothelial growth factor production and basic fibroblast growth factor release
Ishibashi, H., Shiratuchi, T., Nakagawa, K., Onimaru, M., Sugiura, T., Sueishi, K. & Shirasuna, K., Jan 1 2001, In : Oral Oncology. 37, 1, p. 77-83 7 p.Research output: Contribution to journal › Article
Sp1 decoy transfected to carcinoma cells suppresses the expression of vascular endothelial growth factor, transforming growth factor/β1, and tissue factor and also cell growth and invasion activities
Ishibashi, H., Nakagawa, K., Onimaru, M., Castellanous, E. J., Kaneda, Y., Nakashima, Y., Shirasuna, K. & Sueishi, K., Dec 7 2000, In : Cancer Research. 60, 22, p. 6531-6536 6 p.Research output: Contribution to journal › Article