• 535 Citations
  • 13 h-Index
20012018

Research output per year

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Research Output

  • 535 Citations
  • 13 h-Index
  • 53 Article
  • 1 Chapter
  • 1 Letter
2018

Competencies necessary for becoming a leader in the field of community medicine: A Japanese qualitative interview study

Kainuma, M., Kikukawa, M., Nagata, M. & Yoshida, M., Apr 1 2018, In : BMJ open. 8, 4, e020082.

Research output: Contribution to journalArticle

Secondary syphilis with pulmonary involvement

Ohta, A., Furusyo, N., Kishihara, Y., Eiraku, K., Murata, M., Kainuma, M., Toyoda, K., Ogawa, E., Hayashi, T. & Koga, T., Jan 1 2018, In : Internal Medicine. 57, 1, p. 121-126 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017

The traditional Japanese herbal medicine Hachimijiogan Elicits neurite outgrowth effects in PC12 cells and improves cognitive in AD model rats via phosphorylation of CREB

Kubota, K., Fukue, H., Sato, H., Hashimoto, K., Fujikane, A., Moriyama, H., Watanabe, T., Katsurabayashi, S., Kainuma, M. & Iwasaki, K., Nov 21 2017, In : Frontiers in Pharmacology. 8, NOV, 850.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2016

Association of IL28B rs8099917 genotype and female sex with spontaneous clearance of hepatitis C virus infection: a Japanese cross-sectional study

Ikezaki, H., Furusyo, N., Hiramine, S., Ura, K., Mitsumoto-Kaseida, F., Takayama, K., Shimizu, M., Toyoda, K., Ogawa, E., Kainuma, M., Murata, M. & Hayashi, J., Mar 1 2016, In : Archives of Virology. 161, 3, p. 641-648 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Kampo diagnosis based on Sho

Kainuma, M., Jan 1 2016, Methods in Pharmacology and Toxicology. Humana Press Inc., p. 9-18 10 p. (Methods in Pharmacology and Toxicology).

Research output: Chapter in Book/Report/Conference proceedingChapter

The relation between hepatotoxicity and the total coumarin intake from traditional Japanese medicines containing cinnamon bark

Iwata, N., Kainuma, M., Kobayashi, D., Kubota, T., Sugawara, N., Uchida, A., Ozono, S., Yamamuro, Y., Furusyo, N., Ueda, K., Tahara, E. & Shimazoe, T., Jun 20 2016, In : Frontiers in Pharmacology. 7, JUN, 174.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The relation of postprandial plasma glucose and serum endostatin to the urinary albumin excretion of residents with prediabetes: results from the Kyushu and Okinawa Population Study (KOPS)

Shimizu, M., Furusyo, N., Tanaka, Y., Kato, Y., Mitsumoto-Kaseida, F., Takayama, K., Ura, K., Hiramine, S., Hayashi, T., Ikezaki, H., Ihara, T., Mukae, H., Ogawa, E., Toyoda, K., Kainuma, M., Murata, M. & Hayashi, J., Jun 1 2016, In : International Urology and Nephrology. 48, 6, p. 851-857 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2015

A case of granulomatosis with polyangiitis preceded by subacute thyroiditis

Mukae, H., Furusyo, N., Murata, M., Ogawa, E., Kainuma, M., Shimizu, M., Ihara, T. & Hayashi, J., Mar 1 2015, In : Clinical Case Reports. 3, 3, p. 139-144 6 p.

Research output: Contribution to journalArticle

Subclinical carotid atherosclerosis and triglycerides predict the incidence of chronic kidney disease in the Japanese general population: Results from the Kyushu and Okinawa Population Study (KOPS)

Shimizu, M., Furusyo, N., Mitsumoto, F., Takayama, K., Ura, K., Hiramine, S., Ikezaki, H., Ihara, T., Mukae, H., Ogawa, E., Toyoda, K., Kainuma, M., Murata, M. & Hayashi, J., Feb 1 2015, In : Atherosclerosis. 238, 2, p. 207-212 6 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

The association between objective tongue color and endoscopic findings: Results from the Kyushu and Okinawa population study (KOPS)

Kainuma, M., Furusyo, N., Urita, Y., Nagata, M., Ihara, T., Oji, T., Nakaguchi, T., Namiki, T. & Hayashi, J., Oct 16 2015, In : BMC Complementary and Alternative Medicine. 15, 1

Research output: Contribution to journalArticle

6 Citations (Scopus)
2014
2 Citations (Scopus)

Nocturnal difference in the ultra low frequency band of heart rate variability in patients stratified by Kampo medicine prescription

Kainuma, M., Furusyo, N., Ando, S. I., Mukae, H., Ogawa, E., Toyoda, K., Murata, M. & Hayashi, J., 2014, In : Circulation Journal. 78, 8, p. 1924-1927 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Therapeutic drug monitoring of telaprevir in chronic hepatitis C patients receiving telaprevir-based triple therapy is useful for predicting virological response

Furusyo, N., Ogawa, E., Murata, M., Toyoda, K., Ohnishi, H., Eiraku, K., Shimizu, M., Harada, Y., Mitsumoto, F., Takayama, K., Kainuma, M., Okada, K. & Hayashi, J., Feb 1 2014, In : Journal of Antimicrobial Chemotherapy. 69, 2, p. 483-490 8 p., dkt371.

Research output: Contribution to journalArticle

16 Citations (Scopus)

The utility of urinary myo-inositol as a marker of glucose intolerance

Ikezaki, H., Furusyo, N., Okada, K., Ihara, T., Hayashi, T., Ogawa, E., Kainuma, M., Murata, M. & Hayashi, J., Jan 1 2014, In : Diabetes Research and Clinical Practice. 103, 1, p. 88-96 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2013

A case of Fanconi's syndrome caused by long-term administration of adefovir by a patient with chronic hepatitis B

Kumade, E., Furusyo, N., Mitsumoto, F., Ogawa, E., Toyoda, K., Kainuma, M., Masayuki, M. & Hayashi, J., Jan 1 2013, In : Acta Hepatologica Japonica. 54, 3, p. 187-193 7 p.

Research output: Contribution to journalArticle

A case report of human immunodeficiency virus-associated anaplastic lymphoma kinase protein-negative anaplastic large cell lymphoma

Taniai, H., Furusyo, N., Murata, M., Mitsumoto, F., Shimizu, M., Toyoda, K., Ogawa, E., Kainuma, M., Okada, K. & Hayashi, J., Jan 1 2013, In : SpringerPlus. 2, 1, p. 1-5 5 p., 400.

Research output: Contribution to journalArticle

Association between chronic hepatitis C virus infection and high levels of circulating N-terminal pro-brain natriuretic peptide

Okada, K., Furusyo, N., Ogawa, E., Ikezaki, H., Ihara, T., Hayashi, T., Kainuma, M., Murata, M. & Hayashi, J., Feb 1 2013, In : Endocrine. 43, 1, p. 200-205 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Early phase viral kinetics of chronic hepatitis C patients receiving telaprevir-based triple therapy: A comparison of two real-time PCR assays

Ogawa, E., Furusyo, N., Masayuki, M., Toyoda, K., Eiraku, K., Shimizu, M., Harada, Y., Mitsumoto, F., Takayama, K., Okada, K., Kainuma, M. & Hayashi, J., Aug 1 2013, In : Antiviral Research. 99, 2, p. 119-124 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Investigation of Encephalopathy Caused by Shiga Toxin 2c-Producing Escherichia coli Infection in Mice

Amran, M. Y., Fujii, J., Suzuki, S. O., Kolling, G. L., Villanueva, S. Y. A. M., Kainuma, M., Kobayashi, H., Kameyama, H. & Yoshida, S. I., Mar 13 2013, In : PloS one. 8, 3, e58959.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Proposal for effective treatment of Shiga toxin-producing Escherichia coli infection in mice

Amran, M. Y., Fujii, J., Kolling, G. L., Villanueva, S. Y. A. M., Kainuma, M., Kobayashi, H., Kameyama, H. & Yoshida, S. I., Dec 1 2013, In : Microbial Pathogenesis. 65, p. 57-62 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The serum undercarboxylated osteocalcin level and the diet of a Japanese population: Results from the Kyushu and Okinawa Population Study (KOPS)

Furusyo, N., Ihara, T., Hayashi, T., Ikezaki, H., Toyoda, K., Ogawa, E., Okada, K., Kainuma, M., Murata, M. & Hayashi, J., Jun 1 2013, In : Endocrine. 43, 3, p. 635-642 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Valuable antiviral therapeutic options for the treatment of chronic hepatitis C patients with thrombocytopenia

Ogawa, E., Furusyo, N., Murata, M., Ikezaki, H., Ihara, T., Hayashi, T., Toyoda, K., Okada, K., Kainuma, M., Kajiwara, E., Takahashi, K., Satoh, T. & Hayashi, J., Dec 1 2013, In : Journal of Viral Hepatitis. 20, 12, p. 838-846 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2012
2 Citations (Scopus)

A hypertriglyceridemic state increases high sensitivity C-reactive protein of Japanese men with normal glucose tolerance

Okada, K., Furusyo, N., Murata, M., Sawayama, Y., Kainuma, M. & Hayashi, J., Feb 1 2012, In : Endocrine. 41, 1, p. 96-102 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Combination therapy with tsumyakushigyakuto (tong-mai-si-ni-tang) and sekiganryo (chi-wan-liao) and the sequence of medication

Yano, H., Tahara, E., Iwanaga, J., Inutsuka, H., Kubota, M., Kainuma, M., Kimura, H., Kuriyama, K. & Mitsuma, T., Jan 1 2012, In : Journal of Traditional Medicines. 29, 2, p. 74-80 7 p.

Research output: Contribution to journalArticle

Insulin resistance undermines the advantages of IL28B polymorphism in the pegylated interferon alpha-2b and ribavirin treatment of chronic hepatitis C patients with genotype 1

Ogawa, E., Furusyo, N., Murata, M., Ikezaki, H., Ihara, T., Hayashi, T., Toyoda, K., Taniai, H., Okada, K., Kainuma, M. & Hayashi, J., Sep 1 2012, In : Journal of Hepatology. 57, 3, p. 534-540 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Pegylated interferon α-2b plus ribavirin for Japanese chronic hepatitis C patients with normal alanine aminotransferase

Kainuma, M., Furusyo, N., Azuma, K., Kajiwara, E., Takahashi, K., Nomura, H., Tanabe, Y., Satoh, T., Maruyama, T., Nakamuta, M., Kotoh, K., Shimoda, S. & Hayashi, J., Jan 1 2012, In : Hepatology Research. 42, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Raloxifene hydrochloride is an adjuvant antiviral treatment of postmenopausal women with chronic hepatitis C: A randomized trial

Furusyo, N., Ogawa, E., Sudoh, M., Murata, M., Ihara, T., Hayashi, T., Ikezaki, H., Hiramine, S., Mukae, H., Toyoda, K., Taniai, H., Okada, K., Kainuma, M., Kajiwara, E. & Hayashi, J., Dec 1 2012, In : Journal of Hepatology. 57, 6, p. 1186-1192 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2011

[A case of AIDS-associated Kaposi's sarcoma with systemic invasion].

Ikezaki, H., Ogawa, E., Murata, M., Ihara, T., Toyoda, K., Taniai, H., Otaguro, S., Kainuma, M., Sawayama, Y., Furusyo, N. & Hayashi, J., Jan 2011, In : Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 85, 1, p. 54-58 5 p.

Research output: Contribution to journalArticle

Abbott RealTime PCR assay is useful for evaluating virological response to antiviral treatment for chronic hepatitis C

Ikezaki, H., Furusyo, N., Ihara, T., Hayashi, T., Ogawa, E., Toyoda, K., Taniai, H., Kainuma, M., Murata, M. & Hayashi, J., Dec 2011, In : Journal of Infection and Chemotherapy. 17, 6, p. 737-743 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A case of type I diabetes mellitus caused by low-dose, long-term natural interferon a therapy for a patient with chronic hepatitis C

Hayashi, T., Kainuma, M., Taniai, H., Murata, M., Okada, K., Sawayama, Y., Furusyo, N. & Hayashi, J., Jul 14 2011, In : Acta Hepatologica Japonica. 52, 6, p. 335-343 9 p.

Research output: Contribution to journalArticle

Longitudinal assessment of liver stiffness by transient elastography for chronic hepatitis B patients treated with nucleoside analog

Ogawa, E., Furusyo, N., Murata, M., Ohnishi, H., Toyoda, K., Taniai, H., Ihara, T., Ikezaki, H., Hayashi, T., Kainuma, M. & Hayashi, J., Dec 1 2011, In : Hepatology Research. 41, 12, p. 1178-1188 11 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Ribavirin concentration in the later stages of 48 week pegylated interferon-α2b plus ribavirin therapy for chronic hepatitis C is useful for predicting virological response

Furusyo, N., Murata, M., Ogawa, E., Toyoda, K., Ihara, T., Ikezaki, H., Hayashi, T., Koga, T., Kainuma, M. & Hayashi, J., May 1 2011, In : Journal of Antimicrobial Chemotherapy. 66, 5, p. 1127-1139 13 p., dkr034.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Treatment for eradication of Helicobacter pylori infection among chronic hepatitis C patients

Furusyo, N., Walaa, A. H., Eiraku, K., Toyoda, K., Ogawa, E., Ikezaki, H., Ihara, T., Hayashi, T., Kainuma, M., Murata, M. & Hayashi, J., Dec 1 2011, In : Gut and Liver. 5, 4, p. 447-453 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2010

Comparison of the effects of keishibukuryogan and atorvastatin on balloon injury-induced intimal thickening in rat carotid artery

Morimoto, Y., Shibata, Y., Ochiai, S., Ogino, F., Kainuma, M. & Mitsuma, T., Jan 1 2010, In : Journal of Traditional Medicines. 27, 1, p. 30-38 9 p.

Research output: Contribution to journalArticle

Excellent superiority and specificity of COBAS TaqMan HCV assay in an early viral kinetic change during pegylated interferon alpha-2b plus ribavirin treatment

Ogawa, E., Furusyo, N., Toyoda, K., Taniai, H., Otaguro, S., Kainuma, M., Murata, M., Sawayama, Y. & Hayashi, J., Apr 16 2010, In : BMC Gastroenterology. 10, 38.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Pegylated interferon α-2b plus ribavirin for older patients with chronic hepatitis C

Kainuma, M., Furusyo, N., Kajiwara, E., Takahashi, K., Nomura, H., Tanabe, Y., Satoh, T., Maruyama, T., Nakamuta, M., Kotoh, K., Azuma, K., Shimono, J., Shimoda, S. & Hayashi, J., Sep 21 2010, In : World Journal of Gastroenterology. 16, 35, p. 4400-4409 10 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2009

Protein-losing enteropathy during highly active antiretroviral therapy in a patient with AIDS-related disseminated Mycobacterial avium complex infection

Ogawa, E., Murata, M., Unno, M., Otaguro, S., Kainuma, M., Sawayama, Y., Furusyo, N., Yanai, S., Matsumoto, T. & Hayashi, J., Aug 2009, In : Journal of Infection and Chemotherapy. 15, 4, p. 252-256 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2008

Evidence-based efficacy of kampo formulas in a model of non alcoholic fatty liver

Fujimoto, M., Tsuneyama, K., Kainuma, M., Sekiya, N., Goto, H., Takano, Y., Terasawa, K., Selmi, C., Gershwin, M. E. & Shimada, Y., Mar 1 2008, In : Experimental Biology and Medicine. 233, 3, p. 328-337 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Intravenous immunoglobulin therapy for severe arthritis associated with human parvovirus B19 infection

Ogawa, E., Otaguro, S., Murata, M., Kainuma, M., Sawayama, Y., Furusyo, N. & Hayashi, J., Oct 2008, In : Journal of Infection and Chemotherapy. 14, 5, p. 377-382 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2006

Cholesterol-fed rabbit as a unique model of nonalcoholic, nonobese, non-insulin-resistant fatty liver disease with characteristic fibrosis

Kainuma, M., Fujimoto, M., Sekiya, N., Tsuneyama, K., Cheng, C., Takano, Y., Terasawa, K. & Shimada, Y., Oct 1 2006, In : Journal of gastroenterology. 41, 10, p. 971-980 10 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)
2005

Changes of peripheral lymphocyte population in patients with chronic hepatitis C treated with herbal medicine (Maoto) and IFN-ß

Kainuma, M., Kogure, T., Sekiya, N., Mitsuma, T., Shimada, Y. & Terasawa, K., Jan 1 2005, In : Journal of Traditional Medicines. 22, 42403, p. 29-33 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Oren-gedoku-to and Keishi-bukuryo-gan-ryo inhibit the progression of atherosclerosis in diet-induced hypercholesterolemic rabbits

Sekiya, N., Kainuma, M., Hikiami, H., Nakagawa, T., Kouta, K., Shibahara, N., Shimada, Y. & Terasawa, K., Feb 1 2005, In : Biological and Pharmaceutical Bulletin. 28, 2, p. 294-298 5 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2004

A case of interferon rebound therapy treated with combination of IFNβ and Mao-to

Kainuma, M., Sakai, S., Shimada, Y. & Terasawa, K., Jan 1 2004, In : Acta Hepatologica Japonica. 45, 6, p. 303-307 5 p.

Research output: Contribution to journalArticle

Kampo medicine and new criteria for diagnosis of drug-induced liver injury: Sensitivity and specificity

Mantani, N., Kogure, T., Kainuma, M., Shimada, Y. & Terasawa, K., Jan 1 2004, In : Acta Hepatologica Japonica. 45, 7, p. 345-349 5 p.

Research output: Contribution to journalArticle

The effect of a herbal medicine (Mao-to) for the prevention of interferon-induced psychiatric complications in chronic hepatitis C: A pilot study

Kainuma, M., Hikiami, H., Nozaki, K., Hayashi, K., Shimada, Y. & Terasawa, K., Jun 1 2004, In : Human Psychopharmacology. 19, 4, p. 235-241 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

The effects of a herbal medicine (Mao-to) in patients with chronic hepatitis C after injection of IFN-β

Kainuma, M., Sakai, S., Sekiya, N., Mantani, N., Ogata, N., Shimada, Y. & Terasawa, K., Jan 2004, In : Phytomedicine. 11, 1, p. 5-10 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)