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Fingerprint Dive into the research topics where Naoki Ikenaga is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 14 Similar Profiles
Pancreatic Neoplasms Medicine & Life Sciences
Pancreatic Stellate Cells Medicine & Life Sciences
Fibrosis Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Protein-Lysine 6-Oxidase Medicine & Life Sciences
Epithelial-Mesenchymal Transition Medicine & Life Sciences
gemcitabine Medicine & Life Sciences
Collagen Medicine & Life Sciences

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Research Output 2005 2017

  • 881 Citations
  • 15 h-Index
  • 24 Article
72 Citations (Scopus)

Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal

Ikenaga, N., Peng, Z. W., Vaid, K. A., Liu, S. B., Yoshida, S., Sverdlov, D. Y., Mikels-Vigdal, A., Smith, V., Schuppan, D. & Popov, Y. V., Sep 1 2017, In : Gut. 66, 9, p. 1697-1708 12 p.

Research output: Contribution to journalArticle

Open Access
Protein-Lysine 6-Oxidase
Fibrosis
Liver
Hepatocytes
Collagen
34 Citations (Scopus)

Integrin αvβ6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis

Peng, Z. W., Ikenaga, N., Liu, S. B., Sverdlov, D. Y., Vaid, K. A., Dixit, R., Weinreb, P. H., Violette, S., Sheppard, D., Schuppan, D. & Popov, Y., Jan 1 2016, In : Hepatology. 63, 1, p. 217-232 16 p.

Research output: Contribution to journalArticle

Open Access
Integrins
Transforming Growth Factor beta
Hepatocytes
Carcinogenesis
Fibrosis
51 Citations (Scopus)

Lysyl oxidase activity contributes to collagen stabilization during liver fibrosis progression and limits spontaneous fibrosis reversal in mice

Liu, S. B., Ikenaga, N., Peng, Z. W., Sverdlov, D. Y., Greenstein, A., Smith, V., Schuppan, D. & Popov, Y., Apr 1 2016, In : FASEB Journal. 30, 4, p. 1599-1609 11 p.

Research output: Contribution to journalArticle

Protein-Lysine 6-Oxidase
Aminopropionitrile
Liver Cirrhosis
Liver
Fibrosis
21 Citations (Scopus)

A new mdr2-/- mouse model of sclerosing cholangitis with rapid fibrosis progression, early-onset portal hypertension, and liver cancer

Ikenaga, N., Liu, S. B., Sverdlov, D. Y., Yoshida, S., Nasser, I., Ke, Q., Kang, P. M. & Popov, Y., Jan 1 2015, In : American Journal of Pathology. 185, 2, p. 325-334 10 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Portal Hypertension
Liver Neoplasms
Fibrosis
Tumor Burden
50 Citations (Scopus)

Extrahepatic platelet-derived growth factor-β, delivered by platelets, promotes activation of hepatic stellate cells and biliary fibrosis in mice

Yoshida, S., Ikenaga, N., Liu, S. B., Peng, Z. W., Chung, J., Sverdlov, D. Y., Miyamoto, M., Kim, Y. O., Ogawa, S., Arch, R. H., Schuppan, D. & Popov, Y., Dec 1 2014, In : Gastroenterology. 147, 6, p. 1378-1392 15 p.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Platelet-Derived Growth Factor
Proto-Oncogene Proteins c-sis
Platelet Activation
Fibrosis