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Research Output 1995 2020

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1995
54 Citations (Scopus)

Conformational analysis of natural products using long-range carbon-proton coupling constants: Three-dimensional structure of okadaic acid in solution

Matsumori, N., Murata, M. & Tachibana, K., Nov 6 1995, In : Tetrahedron. 51, 45, p. 12229-12238 10 p.

Research output: Contribution to journalArticle

Okadaic Acid
Biological Products
Conformations
Protons
Carbon
93 Citations (Scopus)

Isolation and chemical structure of amphidinol 2, a potent hemolytic compound from marine dinoflagellate Amphidinium klebsii

Paul, G. K., Matsumori, N., Murata, M. & Tachibana, K., Aug 28 1995, In : Tetrahedron Letters. 36, 35, p. 6279-6282 4 p.

Research output: Contribution to journalArticle

Hemolytic Agents
Polyenes
Dinoflagellida
Antifungal Agents
amphidinol 2
41 Citations (Scopus)

Stereochemical assignment of the C35-C39 Acyclic linkage in maitotoxin: completion of stereochemical determination of C15-C134

Sasaki, M., Matsumori, N., Murata, M., Tachibana, K. & Yasumoto, T., Dec 4 1995, In : Tetrahedron Letters. 36, 49, p. 9011-9014 4 p.

Research output: Contribution to journalArticle

Carbon
Nuclear magnetic resonance
Molecules
maitotoxin
C 39
1996
41 Citations (Scopus)

Long-range carbon-proton coupling constants for stereochemical assignment of acyclic structures in natural products: Configuration of the C5-C9 portion of maitotoxin

Matsumori, N., Nonomura, T., Sasaki, M., Murata, M., Tachibana, K., Satake, M. & Yasumoto, T., Feb 19 1996, In : Tetrahedron Letters. 37, 8, p. 1269-1272 4 p.

Research output: Contribution to journalArticle

Biological Products
Protons
Carbon
Experiments
maitotoxin
99 Citations (Scopus)

The Complete Structure of Maitotoxin, Part I: Configuration of the C1-C14 Side Chain

Sasaki, M., Matsumori, N., Maruyama, T., Nonomura, T., Murata, M., Tachibana, K. & Yasumoto, T., Jan 1 1996, In : Angewandte Chemie (International Edition in English). 35, 15, p. 1672-1675 4 p.

Research output: Contribution to journalArticle

maitotoxin
99 Citations (Scopus)

The Complete Structure of Maitotoxin, Part II: Configuration of the C135-C142 Side Chain and Absolute Configuration of the Entire Molecule

Nonomura, T., Sasaki, M., Matsumori, N., Murata, M., Tachibana, K. & Yasumoto, T., Jan 1 1996, In : Angewandte Chemie (International Edition in English). 35, 15, p. 1675-1678 4 p.

Research output: Contribution to journalArticle

Molecules
1997
3 Citations (Scopus)

Analysis of relative configuration of acyclic compounds based on long-range carbon-proton coupling constants determined by two dimensional NMR

Murata, M., Matsumori, N. & Tachibana, K., Jan 1 1997, In : Unknown Journal. 11, p. 749-757 9 p.

Research output: Contribution to journalArticle

nuclear magnetic resonance
Protons
Carbon
Nuclear magnetic resonance
Biological Products
91 Citations (Scopus)

Chemical structures of amphidinols 5 and 6 isolated from marine dinoflagellate Amphidinium klebsii and their cholesterol-dependent membrane disruption

Paul, G. K., Matsumori, N., Konoki, K., Murata, M. & Tachibana, K., Dec 1 1997, In : Journal of Marine Biotechnology. 5, 2-3, p. 124-128 5 p.

Research output: Contribution to journalArticle

Dinoflagellida
Hemolytic Agents
Cholesterol
Membranes
Polyenes
30 Citations (Scopus)

Involvement of AfsA in A-factor biosynthesis as a key enzyme

Ando, N., Matsumori, N., Sakuda, S., Beppu, T. & Horinouchi, S., Jan 1 1997, In : Journal of Antibiotics. 50, 10, p. 847-852 6 p.

Research output: Contribution to journalArticle

Streptomyces griseus
Enzymes
Fatty Acids
Cerulenin
Keto Acids
1998
13 Citations (Scopus)

Absolute structure and total synthesis of lipogrammistin-A, a lipophilic ichthyotoxin of the soapfish

Onuki, H., Ito, K., Kobayashi, Y., Matsumori, N., Tachibana, K. & Fusetani, N., Jun 12 1998, In : Journal of Organic Chemistry. 63, 12, p. 3925-3932 8 p.

Research output: Contribution to journalArticle

Stereochemistry
Fish
Skin
Derivatives
Degradation
1999
741 Citations (Scopus)

Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

Kudo, N., Matsumori, N., Taoka, H., Fujiwara, D., Schreiner, E. P., Wolff, B., Yoshida, M. & Horinouchi, S., Aug 3 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 16, p. 9112-9117 6 p.

Research output: Contribution to journalArticle

Cysteine
Ethylmaleimide
Nuclear Export Signals
Cell Nucleus Active Transport
leptomycin B
524 Citations (Scopus)

Stereochemical determination of acyclic structures based on carbon- proton spin-coupling constants. A method of configuration analysis for natural products

Matsumori, N., Kaneno, D., Murata, M., Nakamura, H. & Tachibana, K., Feb 5 1999, In : Journal of Organic Chemistry. 64, 3, p. 866-876 11 p.

Research output: Contribution to journalArticle

Biological Products
Protons
Carbon
Stereochemistry
Carboxylic Acids
2000
41 Citations (Scopus)

Absolute configuration of aflastatin A, a specific inhibitor of aflatoxin production by Aspergillus parasiticus

Ikeda, H., Matsumori, N., Ono, M., Suzuki, A., Isogai, A., Nagasawa, H. & Sakuda, S., Jan 28 2000, In : Journal of Organic Chemistry. 65, 2, p. 438-444 7 p.

Research output: Contribution to journalArticle

Aflatoxins
Aspergillus
Stereochemistry
Molecules
Methyl Ethers
2002
58 Citations (Scopus)

Amphotericin B covalent dimers forming sterol-dependent ion-permeable membrane channels

Matsumori, N., Yamaji, N., Matsuoka, S., Oishi, T. & Murata, M., Apr 24 2002, In : Journal of the American Chemical Society. 124, 16, p. 4180-4181 2 p.

Research output: Contribution to journalArticle

Amphotericin B
Sterols
Ion Channels
Dimers
Ions
32 Citations (Scopus)

Amphotericin B Dimers with Bisamide Linkage Bearing Powerful Membrane-Permeabilizing Activity

Yamaji, N., Matsumori, N., Matsuoka, S., Oishi, T. & Murata, M., Jun 13 2002, In : Organic Letters. 4, 12, p. 2087-2089 3 p.

Research output: Contribution to journalArticle

Bearings (structural)
1,6-diaminohexane
Amphotericin B
linkages
Dimers
2003
27 Citations (Scopus)

Amphotericin B-phospholipid covalent conjugates: Dependence of membrane-permeabilizing activity on acyl-chain length

Matsuoka, S., Matsumori, N. & Murata, M., Nov 21 2003, In : Organic and Biomolecular Chemistry. 1, 22, p. 3882-3884 3 p.

Research output: Contribution to journalArticle

Amphotericin B
Ion Channels
Chain length
Phospholipids
membranes
2004
16 Citations (Scopus)

Amphotericin B covalent dimers bearing a tartarate linkage

Matsumori, N., Masuda, R. & Murata, M., Dec 1 2004, In : Chemistry and Biodiversity. 1, 2, p. 346-352 7 p.

Research output: Contribution to journalArticle

Bearings (structural)
Amphotericin B
Ion Channels
Dimers
Ions
33 Citations (Scopus)

An amphotericin B-ergosterol covalent conjugate with powerful membrane permeabilizing activity

Matsumori, N., Eiraku, N., Matsuoka, S., Oishi, T., Murata, M., Aoki, T. & Ide, T., May 1 2004, In : Chemistry and Biology. 11, 5, p. 673-679 7 p.

Research output: Contribution to journalArticle

Ergosterol
Amphotericin B
Membranes
Cholesterol
Bearings (structural)
43 Citations (Scopus)

Membrane-permeabilizing activities of amphidinol 3, polyene-polyhydroxy antifungal from a marine dinoflagellate

Houdai, T., Matsuoka, S., Matsumori, N. & Murata, M., Nov 17 2004, In : Biochimica et Biophysica Acta - Biomembranes. 1667, 1, p. 91-100 10 p.

Research output: Contribution to journalArticle

Polyenes
Dinoflagellida
Membranes
Filipin
Liposomes
4 Citations (Scopus)

Synthesis and conformation of deuterated spermidine for investigating weak interaction with polyanionic biomolecules

Maruyoshi, K., Demura, T., Sagane, T., Matsumori, N., Oishi, T. & Murata, M., Jun 7 2004, In : Tetrahedron. 60, 24, p. 5163-5170 8 p.

Research output: Contribution to journalArticle

Spermidine
Biomolecules
Conformations
Polyamines
Spermine
2005
21 Citations (Scopus)

Bioactive fluorinated derivative of amphotericin B

Matsumori, N., Umegawa, Y., Oishi, T. & Murata, M., Aug 1 2005, In : Bioorganic and Medicinal Chemistry Letters. 15, 15, p. 3565-3567 3 p.

Research output: Contribution to journalArticle

Amphotericin B
Derivatives
Fluorination
Fluorine
Halogenation
42 Citations (Scopus)

Dominant formation of a single-length channel by amphotericin B in dimyristoylphosphatidylcholine membrane evidenced by 13C- 31P rotational echo double resonance

Matsuoka, S., Ikeuchi, H., Matsumori, N. & Murata, M., Jan 18 2005, In : Biochemistry. 44, 2, p. 704-710 7 p.

Research output: Contribution to journalArticle

Dimyristoylphosphatidylcholine
Amphotericin B
Membranes
Carbon
Experiments
48 Citations (Scopus)

Hairpin conformation of amphidinols possibly accounting for potent membrane permeabilizing activities

Houdai, T., Matsuoka, S., Morsy, N., Matsumori, N., Satake, M. & Murata, M., Mar 14 2005, In : Tetrahedron. 61, 11, p. 2795-2802 8 p.

Research output: Contribution to journalArticle

Conformations
Membranes
Polyenes
Lipid bilayers
Dinoflagellida
53 Citations (Scopus)

Isolation and structure elucidation of a new amphidinol with a truncated polyhydroxyl chain from Amphidinium klebsii

Morsy, N., Matsuoka, S., Houdai, T., Matsumori, N., Adachi, S., Murata, M., Iwashita, T. & Fujita, T., Sep 5 2005, In : Tetrahedron. 61, 36, p. 8606-8610 5 p.

Research output: Contribution to journalArticle

Polyenes
Dinoflagellida
Sulfates
Esters
Carbon
27 Citations (Scopus)

Ladder-shaped polyether compound, desulfated yessotoxin, interacts with membrane-integral α-helix peptides

Mori, M., Oishi, T., Matsuoka, S., Ujihara, S., Matsumori, N., Murata, M., Satake, M., Oshima, Y., Matsushita, N. & Aimoto, S., Sep 1 2005, In : Bioorganic and Medicinal Chemistry. 13, 17, p. 5099-5103 5 p.

Research output: Contribution to journalArticle

Polyethers
Ladders
Ciguatoxins
Membranes
Oligomers
69 Citations (Scopus)
Amino Sugars
Ergosterol
Amino sugars
Amphotericin B
Sterols
2006
3 Citations (Scopus)
Amphotericin B
Ion Channels
Isotopes
Labeling
Ergosterol
21 Citations (Scopus)

Design and synthesis of an artificial ladder-shaped polyether that interacts with glycophorin A

Torikai, K., Yari, H., Mori, M., Ujihara, S., Matsumori, N., Murata, M. & Oishi, T., Dec 15 2006, In : Bioorganic and Medicinal Chemistry Letters. 16, 24, p. 6355-6359 5 p.

Research output: Contribution to journalArticle

Glycophorin
Polyethers
Ladders
Ether
Ciguatoxins
21 Citations (Scopus)

Detailed description of the conformation and location of membrane-bound erythromycin A using isotropic bicelles

Matsumori, N., Morooka, A. & Murata, M., Jun 15 2006, In : Journal of Medicinal Chemistry. 49, 12, p. 3501-3508 8 p.

Research output: Contribution to journalArticle

Erythromycin
Conformations
Membranes
Pharmaceutical Preparations
Biological membranes
26 Citations (Scopus)
Ergosterol
Amphotericin B
Ion Channels
Dimyristoylphosphatidylcholine
Conformations
24 Citations (Scopus)

Membrane interaction of amphotericin B as single-length assembly examined by solid state NMR for uniformly 13C-enriched agent

Matsuoka, S., Ikeuchi, H., Umegawa, Y., Matsumori, N. & Murata, M., Oct 1 2006, In : Bioorganic and Medicinal Chemistry. 14, 19, p. 6608-6614 7 p.

Research output: Contribution to journalArticle

Amphotericin B
Nuclear magnetic resonance
Membranes
Bearings (structural)
Pharmaceutical Preparations
51 Citations (Scopus)

Structures of new amphidinols with truncated polyhydroxyl chain and their membrane-permeabilizing activities

Morsy, N., Houdai, T., Matsuoka, S., Matsumori, N., Adachi, S., Oishi, T., Murata, M., Iwashita, T. & Fujita, T., Oct 1 2006, In : Bioorganic and Medicinal Chemistry. 14, 19, p. 6548-6554 7 p.

Research output: Contribution to journalArticle

Polyenes
Dinoflagellida
Structure-Activity Relationship
Bioactivity
Chain length
35 Citations (Scopus)

Synthesis of 28- 19 F-amphotericin B methyl ester

Tsuchikawa, H., Matsushita, N., Matsumori, N., Murata, M. & Oishi, T., Aug 28 2006, In : Tetrahedron Letters. 47, 35, p. 6187-6191 5 p.

Research output: Contribution to journalArticle

Amphotericin B
Derivatives
Polyenes
Cross Reactions
Biological Products
2007
17 Citations (Scopus)

Amphotericin B covalent dimers with carbonyl-amino linkage: a new probe for investigating ion channel assemblies

Umegawa, Y., Matsumori, N., Oishi, T. & Murata, M., May 7 2007, In : Tetrahedron Letters. 48, 19, p. 3393-3396 4 p.

Research output: Contribution to journalArticle

Amphotericin B
Ion Channels
Dimers
Ions
Molecules
11 Citations (Scopus)

Assignment of the absolute configuration of blasticidin A and revision of that of aflastatin A

Sakuda, S., Matsumori, N., Furihata, K. & Nagasawa, H., Apr 2 2007, In : Tetrahedron Letters. 48, 14, p. 2527-2531 5 p.

Research output: Contribution to journalArticle

Stereochemistry
Aflatoxins
Aspergillus
Nuclear magnetic resonance
blasticidin A
33 Citations (Scopus)

Conformation and location of membrane-bound salinomycin-sodium complex deduced from NMR in isotropic bicelles

Matsumori, N., Morooka, A. & Murata, M., Dec 5 2007, In : Journal of the American Chemical Society. 129, 48, p. 14989-14995 7 p.

Research output: Contribution to journalArticle

Conformations
Sodium
Nuclear magnetic resonance
Membranes
Biological membranes
14 Citations (Scopus)

Conformation and position of membrane-bound amphotericin B deduced from NMR in SDS micelles

Matsumori, N., Houdai, T. & Murata, M., Feb 2 2007, In : Journal of Organic Chemistry. 72, 3, p. 700-706 7 p.

Research output: Contribution to journalArticle

Micelles
Amphotericin B
Conformations
Nuclear magnetic resonance
Membranes
2008
3 Citations (Scopus)

Accurate measurement of vicinal carbon-hydrogen coupling constants via ammonium nitrogen based on HMBC experiments

Yamaguchi, T., Marayoshi, K., Matsumori, N. & Murata, M., Dec 1 2008, In : Chemistry Letters. 37, 11, p. 1172-1173 2 p.

Research output: Contribution to journalArticle

1-Deoxynojirimycin
Ammonium Compounds
Conformations
Hydrogen
Nitrogen
47 Citations (Scopus)

Combinatorial synthesis of the 1,5-polyol system based on cross metathesis: Structure revision of amphidinol 3

Oishi, T., Kanemoto, M., Swasono, R., Matsumori, N. & Murata, M., Dec 1 2008, In : Organic Letters. 10, 22, p. 5203-5206 4 p.

Research output: Contribution to journalArticle

metathesis
degradation
nuclear magnetic resonance
synthesis
products
42 Citations (Scopus)

Complex formation of amphotericin B in sterol-containing membranes as evidenced by surface plasmon resonance

Mouri, R., Konoki, K., Matsumori, N., Oishi, T. & Murata, M., Jul 29 2008, In : Biochemistry. 47, 30, p. 7807-7815 9 p.

Research output: Contribution to journalArticle

Surface Plasmon Resonance
Surface plasmon resonance
Amphotericin B
Sterols
Membranes
30 Citations (Scopus)

Convergent synthesis and biological activity of the WXYZA′B′ C′ ring system of maitotoxin

Oishi, T., Hasegawa, F., Torikai, K., Konoki, K., Matsumori, N. & Murata, M., Dec 1 2008, In : Organic Letters. 10, 16, p. 3599-3602 4 p.

Research output: Contribution to journalArticle

activity (biology)
Bioactivity
rings
synthesis
fragments
25 Citations (Scopus)

Design and synthesis of ladder-shaped tetracyclic, heptacyclic, and decacyclic ethers and evaluation of the interaction with transmembrane proteins

Torikai, K., Oishi, T., Ujihara, S., Matsumori, N., Konoki, K., Murata, M. & Aimoto, S., Aug 6 2008, In : Journal of the American Chemical Society. 130, 31, p. 10217-10226 10 p.

Research output: Contribution to journalArticle

Ethers
Polyethers
Ladders
Proteins
Glycophorin
25 Citations (Scopus)

Effects of lipid constituents on membrane-permeabilizing activity of amphidinols

Morsy, N., Houdai, T., Konoki, K., Matsumori, N., Oishi, T. & Murata, M., Mar 15 2008, In : Bioorganic and Medicinal Chemistry. 16, 6, p. 3084-3090 7 p.

Research output: Contribution to journalArticle

Sterols
Membranes
Lipids
Phosphatidylcholines
Polyenes
30 Citations (Scopus)

Ergosterol increases the intermolecular distance of amphotericin B in the membrane-bound assembly as evidenced by solid-state NMR

Umegawa, Y., Matsumori, N., Oishi, T. & Murata, M., Dec 23 2008, In : Biochemistry. 47, 51, p. 13463-13469 7 p.

Research output: Contribution to journalArticle

Ergosterol
Amphotericin B
Nuclear magnetic resonance
Membranes
Sterols
14 Citations (Scopus)

Interaction of ladder-shaped polyethers with transmembrane α-helix of glycophorin A as evidenced by saturation transfer difference NMR and surface plasmon resonance

Ujihara, S., Oishi, T., Torikai, K., Konoki, K., Matsumori, N., Murata, M., Oshima, Y. & Aimoto, S., Dec 1 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 23, p. 6115-6118 4 p.

Research output: Contribution to journalArticle

Glycophorin
Surface Plasmon Resonance
Polyethers
Ladders
Surface plasmon resonance
16 Citations (Scopus)

Orientation of fluorinated cholesterol in lipid bilayers analyzed by 19F tensor calculation and solid-state NMR

Matsumori, N., Kasai, Y., Oishi, T., Murata, M. & Nomura, K., Apr 9 2008, In : Journal of the American Chemical Society. 130, 14, p. 4757-4766 10 p.

Research output: Contribution to journalArticle

Lipid bilayers
Cholesterol
Lipid Bilayers
Tensors
Nuclear magnetic resonance
10 Citations (Scopus)

Roles of integral protein in membrane permeabilization by amphidinols

Morsy, N., Konoki, K., Houdai, T., Matsumori, N., Oishi, T., Murata, M. & Aimoto, S., Jun 1 2008, In : Biochimica et Biophysica Acta - Biomembranes. 1778, 6, p. 1453-1459 7 p.

Research output: Contribution to journalArticle

Glycophorin
Membrane Proteins
Membranes
Lipid bilayers
Surface Plasmon Resonance
37 Citations (Scopus)

Self-assembled amphotericin B is probably surrounded by ergosterol: Bimolecular interactions as evidenced by solid-state NMR and CD spectra

Kasai, Y., Matsumori, N., Umegawa, Y., Matsuoka, S., Ueno, H., Ikeuchi, H., Oishi, T. & Murata, M., Feb 11 2008, In : Chemistry - A European Journal. 14, 4, p. 1178-1185 8 p.

Research output: Contribution to journalArticle

Ergosterol
Amphotericin B
Cholesterol
Nuclear magnetic resonance
Membranes
26 Citations (Scopus)

Structure of membrane-bound amphidinol 3 in isotropic small bicelles

Houdai, T., Matsumori, N. & Murata, M., Dec 1 2008, In : Organic Letters. 10, 19, p. 4191-4194 4 p.

Research output: Contribution to journalArticle

membranes
Membranes
Biological membranes
Micelles
Conformations
2009
9 Citations (Scopus)

Amphotericin B-induced ion flux is markedly attenuated in phosphatidylglycerol membrane as evidenced by a newly devised fluorometric method

Takano, T., Konoki, K., Matsumori, N. & Murata, M., Sep 1 2009, In : Bioorganic and Medicinal Chemistry. 17, 17, p. 6301-6304 4 p.

Research output: Contribution to journalArticle

Phosphatidylglycerols
Amphotericin B
Liposomes
Ions
Fluxes