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Research Output 1995 2020

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Article
2012
3 Citations (Scopus)

Possible conformation of amphotericin B dimer in membrane-bound assembly as deduced from solid-state NMR

Umegawa, Y., Adachi, T., Matsumori, N. & Murata, M., Oct 1 2012, In : Bioorganic and Medicinal Chemistry. 20, 19, p. 5699-5704 6 p.

Research output: Contribution to journalArticle

Amphotericin B
Dimers
Conformations
Nuclear magnetic resonance
Membranes
2011
9 Citations (Scopus)

Channels formed by amphotericin B covalent dimers exhibit rectification

Hirano, M., Takeuchi, Y., Matsumori, N., Murata, M. & Ide, T., Apr 1 2011, In : Journal of Membrane Biology. 240, 3, p. 159-164 6 p.

Research output: Contribution to journalArticle

Amphotericin B
Antifungal Agents
Ion Channels
Fungi
4 Citations (Scopus)

Conformations of spermine in adenosine triphosphate complex: The structural basis for weak bimolecular interactions of major cellular electrolytes

Maruyoshi, K., Yamaguchi, T., Demura, T., Matsumori, N., Oishi, T. & Murata, M., Apr 18 2011, In : Chemistry - A European Journal. 17, 17, p. 4788-4795 8 p.

Research output: Contribution to journalArticle

Spermine
Electrolytes
Nuclear magnetic resonance spectroscopy
Conformations
Phosphates
6 Citations (Scopus)

Design and synthesis of sphingomyelin-cholesterol conjugates and their formation of ordered membranes

Matsumori, N., Tanada, N., Nozu, K., Okazaki, H., Oishi, T. & Murata, M., Jul 25 2011, In : Chemistry - A European Journal. 17, 31, p. 8568-8575 8 p.

Research output: Contribution to journalArticle

Sphingomyelins
Cholesterol
Membranes
Lipids
Molecular recognition
11 Citations (Scopus)

Fluorinated cholesterol retains domain-forming activity in sphingomyelin bilayers

Matsumori, N., Okazaki, H., Nomura, K. & Murata, M., Jul 2011, In : Chemistry and Physics of Lipids. 164, 5, p. 401-408 8 p.

Research output: Contribution to journalArticle

Sphingomyelins
Cholesterol
Dimyristoylphosphatidylcholine
Molecular Probes
Nuclear magnetic resonance
3 Citations (Scopus)

Lysine proximity significantly affects glycation of lysine-containing collagen model peptides

Kitamura, A., Matsui, K., Konoki, K., Matsumori, N., Murata, M., Kawakami, T. & Aimoto, S., Apr 1 2011, In : Bioorganic and Medicinal Chemistry. 19, 7, p. 2125-2129 5 p.

Research output: Contribution to journalArticle

Advanced Glycosylation End Products
Lysine
Collagen
Peptides
Glucose
5 Citations (Scopus)

Synthesis of 6-F-ergosterol and its influence on membrane-permeabilization of amphotericin B and amphidinol 3

Kasai, Y., Matsumori, N., Ueno, H., Nonomura, K., Yano, S., Michio, M. & Oishi, T., Mar 1 2011, In : Organic and Biomolecular Chemistry. 9, 5, p. 1437-1442 6 p.

Research output: Contribution to journalArticle

Amphotericin B
Ergosterol
membranes
Membranes
Sterols
2010
10 Citations (Scopus)

Detection of Rap1A as a yessotoxin binding protein from blood cell membranes

Ujihara, S., Oishi, T., Mouri, R., Tamate, R., Konoki, K., Matsumori, N., Murata, M., Oshima, Y., Sugiyama, N., Tomita, M. & Ishihama, Y., Nov 15 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 22, p. 6443-6446 4 p.

Research output: Contribution to journalArticle

Cell membranes
Blood Cells
Carrier Proteins
Blood
Polyethers
17 Citations (Scopus)

Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance

Swasono, R. T., Mouri, R., Morsy, N., Matsumori, N., Oishi, T. & Murata, M., Apr 1 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 7, p. 2215-2218 4 p.

Research output: Contribution to journalArticle

Surface Plasmon Resonance
Surface plasmon resonance
Sterols
Membranes
Ergosterol
10 Citations (Scopus)

Structural reevaluations of amphidinol 3, a potent antifungal compound from dinoflagellate

Swasono, R. T., Kanemoto, M., Matsumori, N., Oishi, T. & Murata, M., Feb 28 2010, In : Heterocycles. 82, 2, p. 1359-1369 11 p.

Research output: Contribution to journalArticle

Dinoflagellida
Organic solvents
Nuclear magnetic resonance
Membranes
amphidinol 3
2009
9 Citations (Scopus)

Amphotericin B-induced ion flux is markedly attenuated in phosphatidylglycerol membrane as evidenced by a newly devised fluorometric method

Takano, T., Konoki, K., Matsumori, N. & Murata, M., Sep 1 2009, In : Bioorganic and Medicinal Chemistry. 17, 17, p. 6301-6304 4 p.

Research output: Contribution to journalArticle

Phosphatidylglycerols
Amphotericin B
Liposomes
Ions
Fluxes
7 Citations (Scopus)

Conformational change of spermidine upon interaction with adenosine triphosphate in aqueous solution

Maruyoshi, K., Nonaka, K., Sagane, T., Demura, T., Yamaguchi, T., Matsumori, N., Oishi, T. & Murata, M., Feb 2 2009, In : Chemistry - A European Journal. 15, 7, p. 1618-1626 9 p.

Research output: Contribution to journalArticle

Spermidine
Conformations
Adenosine Triphosphate
Polyamines
Phospholipids
50 Citations (Scopus)

Direct interaction between amphotericin B and ergosterol in lipid bilayers as revealed by 2H NMR spectroscopy

Matsumori, N., Tahara, K., Yamamoto, H., Morooka, A., Doi, M., Oishi, T. & Murata, M., Aug 26 2009, In : Journal of the American Chemical Society. 131, 33, p. 11855-11860 6 p.

Research output: Contribution to journalArticle

Ergosterol
Lipid bilayers
Cholesterol
Lipid Bilayers
Amphotericin B
13 Citations (Scopus)

Ion channel complex of antibiotics as viewed by NMR

Murata, M., Kasai, Y., Umegawa, Y., Matsushita, N., Tsuchikawa, H., Matsumori, N. & Oishi, T., Jul 24 2009, In : Pure and Applied Chemistry. 81, 6, p. 1123-1129 7 p.

Research output: Contribution to journalArticle

Amphotericin B
Antibiotics
Ion Channels
Nuclear magnetic resonance
Ergosterol
10 Citations (Scopus)

Surface plasmon resonance-based detection of ladder-shaped polyethers by inhibition detection method

Mouri, R., Oishi, T., Torikai, K., Ujihara, S., Matsumori, N., Murata, M. & Oshima, Y., May 15 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 10, p. 2824-2828 5 p.

Research output: Contribution to journalArticle

Surface Plasmon Resonance
Polyethers
Ladders
Surface plasmon resonance
Ciguatoxins
7 Citations (Scopus)

Synthesis of 25- 13c-amphotericin B methyl ester: A molecular probe for solid-state NMR measurements

Matsushita, N., Matsuo, Y., Tsuchikawa, H., Matsumori, N., Murata, M. & Oishi, T., Jul 20 2009, In : Chemistry Letters. 38, 2, p. 114-115 2 p.

Research output: Contribution to journalArticle

Molecular Probes
Amphotericin B
Nuclear magnetic resonance
Polyenes
Biological Products
2008
3 Citations (Scopus)

Accurate measurement of vicinal carbon-hydrogen coupling constants via ammonium nitrogen based on HMBC experiments

Yamaguchi, T., Marayoshi, K., Matsumori, N. & Murata, M., Dec 1 2008, In : Chemistry Letters. 37, 11, p. 1172-1173 2 p.

Research output: Contribution to journalArticle

1-Deoxynojirimycin
Ammonium Compounds
Conformations
Hydrogen
Nitrogen
47 Citations (Scopus)

Combinatorial synthesis of the 1,5-polyol system based on cross metathesis: Structure revision of amphidinol 3

Oishi, T., Kanemoto, M., Swasono, R., Matsumori, N. & Murata, M., Dec 1 2008, In : Organic Letters. 10, 22, p. 5203-5206 4 p.

Research output: Contribution to journalArticle

metathesis
degradation
nuclear magnetic resonance
synthesis
products
42 Citations (Scopus)

Complex formation of amphotericin B in sterol-containing membranes as evidenced by surface plasmon resonance

Mouri, R., Konoki, K., Matsumori, N., Oishi, T. & Murata, M., Jul 29 2008, In : Biochemistry. 47, 30, p. 7807-7815 9 p.

Research output: Contribution to journalArticle

Surface Plasmon Resonance
Surface plasmon resonance
Amphotericin B
Sterols
Membranes
30 Citations (Scopus)

Convergent synthesis and biological activity of the WXYZA′B′ C′ ring system of maitotoxin

Oishi, T., Hasegawa, F., Torikai, K., Konoki, K., Matsumori, N. & Murata, M., Dec 1 2008, In : Organic Letters. 10, 16, p. 3599-3602 4 p.

Research output: Contribution to journalArticle

activity (biology)
Bioactivity
rings
synthesis
fragments
25 Citations (Scopus)

Design and synthesis of ladder-shaped tetracyclic, heptacyclic, and decacyclic ethers and evaluation of the interaction with transmembrane proteins

Torikai, K., Oishi, T., Ujihara, S., Matsumori, N., Konoki, K., Murata, M. & Aimoto, S., Aug 6 2008, In : Journal of the American Chemical Society. 130, 31, p. 10217-10226 10 p.

Research output: Contribution to journalArticle

Ethers
Polyethers
Ladders
Proteins
Glycophorin
25 Citations (Scopus)

Effects of lipid constituents on membrane-permeabilizing activity of amphidinols

Morsy, N., Houdai, T., Konoki, K., Matsumori, N., Oishi, T. & Murata, M., Mar 15 2008, In : Bioorganic and Medicinal Chemistry. 16, 6, p. 3084-3090 7 p.

Research output: Contribution to journalArticle

Sterols
Membranes
Lipids
Phosphatidylcholines
Polyenes
30 Citations (Scopus)

Ergosterol increases the intermolecular distance of amphotericin B in the membrane-bound assembly as evidenced by solid-state NMR

Umegawa, Y., Matsumori, N., Oishi, T. & Murata, M., Dec 23 2008, In : Biochemistry. 47, 51, p. 13463-13469 7 p.

Research output: Contribution to journalArticle

Ergosterol
Amphotericin B
Nuclear magnetic resonance
Membranes
Sterols
14 Citations (Scopus)

Interaction of ladder-shaped polyethers with transmembrane α-helix of glycophorin A as evidenced by saturation transfer difference NMR and surface plasmon resonance

Ujihara, S., Oishi, T., Torikai, K., Konoki, K., Matsumori, N., Murata, M., Oshima, Y. & Aimoto, S., Dec 1 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 23, p. 6115-6118 4 p.

Research output: Contribution to journalArticle

Glycophorin
Surface Plasmon Resonance
Polyethers
Ladders
Surface plasmon resonance
16 Citations (Scopus)

Orientation of fluorinated cholesterol in lipid bilayers analyzed by 19F tensor calculation and solid-state NMR

Matsumori, N., Kasai, Y., Oishi, T., Murata, M. & Nomura, K., Apr 9 2008, In : Journal of the American Chemical Society. 130, 14, p. 4757-4766 10 p.

Research output: Contribution to journalArticle

Lipid bilayers
Cholesterol
Lipid Bilayers
Tensors
Nuclear magnetic resonance
10 Citations (Scopus)

Roles of integral protein in membrane permeabilization by amphidinols

Morsy, N., Konoki, K., Houdai, T., Matsumori, N., Oishi, T., Murata, M. & Aimoto, S., Jun 1 2008, In : Biochimica et Biophysica Acta - Biomembranes. 1778, 6, p. 1453-1459 7 p.

Research output: Contribution to journalArticle

Glycophorin
Membrane Proteins
Membranes
Lipid bilayers
Surface Plasmon Resonance
37 Citations (Scopus)

Self-assembled amphotericin B is probably surrounded by ergosterol: Bimolecular interactions as evidenced by solid-state NMR and CD spectra

Kasai, Y., Matsumori, N., Umegawa, Y., Matsuoka, S., Ueno, H., Ikeuchi, H., Oishi, T. & Murata, M., Feb 11 2008, In : Chemistry - A European Journal. 14, 4, p. 1178-1185 8 p.

Research output: Contribution to journalArticle

Ergosterol
Amphotericin B
Cholesterol
Nuclear magnetic resonance
Membranes
26 Citations (Scopus)

Structure of membrane-bound amphidinol 3 in isotropic small bicelles

Houdai, T., Matsumori, N. & Murata, M., Dec 1 2008, In : Organic Letters. 10, 19, p. 4191-4194 4 p.

Research output: Contribution to journalArticle

membranes
Membranes
Biological membranes
Micelles
Conformations
2007
17 Citations (Scopus)

Amphotericin B covalent dimers with carbonyl-amino linkage: a new probe for investigating ion channel assemblies

Umegawa, Y., Matsumori, N., Oishi, T. & Murata, M., May 7 2007, In : Tetrahedron Letters. 48, 19, p. 3393-3396 4 p.

Research output: Contribution to journalArticle

Amphotericin B
Ion Channels
Dimers
Ions
Molecules
11 Citations (Scopus)

Assignment of the absolute configuration of blasticidin A and revision of that of aflastatin A

Sakuda, S., Matsumori, N., Furihata, K. & Nagasawa, H., Apr 2 2007, In : Tetrahedron Letters. 48, 14, p. 2527-2531 5 p.

Research output: Contribution to journalArticle

Stereochemistry
Aflatoxins
Aspergillus
Nuclear magnetic resonance
blasticidin A
33 Citations (Scopus)

Conformation and location of membrane-bound salinomycin-sodium complex deduced from NMR in isotropic bicelles

Matsumori, N., Morooka, A. & Murata, M., Dec 5 2007, In : Journal of the American Chemical Society. 129, 48, p. 14989-14995 7 p.

Research output: Contribution to journalArticle

Conformations
Sodium
Nuclear magnetic resonance
Membranes
Biological membranes
14 Citations (Scopus)

Conformation and position of membrane-bound amphotericin B deduced from NMR in SDS micelles

Matsumori, N., Houdai, T. & Murata, M., Feb 2 2007, In : Journal of Organic Chemistry. 72, 3, p. 700-706 7 p.

Research output: Contribution to journalArticle

Micelles
Amphotericin B
Conformations
Nuclear magnetic resonance
Membranes
2006
3 Citations (Scopus)
Amphotericin B
Ion Channels
Isotopes
Labeling
Ergosterol
21 Citations (Scopus)

Design and synthesis of an artificial ladder-shaped polyether that interacts with glycophorin A

Torikai, K., Yari, H., Mori, M., Ujihara, S., Matsumori, N., Murata, M. & Oishi, T., Dec 15 2006, In : Bioorganic and Medicinal Chemistry Letters. 16, 24, p. 6355-6359 5 p.

Research output: Contribution to journalArticle

Glycophorin
Polyethers
Ladders
Ether
Ciguatoxins
21 Citations (Scopus)

Detailed description of the conformation and location of membrane-bound erythromycin A using isotropic bicelles

Matsumori, N., Morooka, A. & Murata, M., Jun 15 2006, In : Journal of Medicinal Chemistry. 49, 12, p. 3501-3508 8 p.

Research output: Contribution to journalArticle

Erythromycin
Conformations
Membranes
Pharmaceutical Preparations
Biological membranes
26 Citations (Scopus)
Ergosterol
Amphotericin B
Ion Channels
Dimyristoylphosphatidylcholine
Conformations
24 Citations (Scopus)

Membrane interaction of amphotericin B as single-length assembly examined by solid state NMR for uniformly 13C-enriched agent

Matsuoka, S., Ikeuchi, H., Umegawa, Y., Matsumori, N. & Murata, M., Oct 1 2006, In : Bioorganic and Medicinal Chemistry. 14, 19, p. 6608-6614 7 p.

Research output: Contribution to journalArticle

Amphotericin B
Nuclear magnetic resonance
Membranes
Bearings (structural)
Pharmaceutical Preparations
51 Citations (Scopus)

Structures of new amphidinols with truncated polyhydroxyl chain and their membrane-permeabilizing activities

Morsy, N., Houdai, T., Matsuoka, S., Matsumori, N., Adachi, S., Oishi, T., Murata, M., Iwashita, T. & Fujita, T., Oct 1 2006, In : Bioorganic and Medicinal Chemistry. 14, 19, p. 6548-6554 7 p.

Research output: Contribution to journalArticle

Polyenes
Dinoflagellida
Structure-Activity Relationship
Bioactivity
Chain length
35 Citations (Scopus)

Synthesis of 28- 19 F-amphotericin B methyl ester

Tsuchikawa, H., Matsushita, N., Matsumori, N., Murata, M. & Oishi, T., Aug 28 2006, In : Tetrahedron Letters. 47, 35, p. 6187-6191 5 p.

Research output: Contribution to journalArticle

Amphotericin B
Derivatives
Polyenes
Cross Reactions
Biological Products
2005
21 Citations (Scopus)

Bioactive fluorinated derivative of amphotericin B

Matsumori, N., Umegawa, Y., Oishi, T. & Murata, M., Aug 1 2005, In : Bioorganic and Medicinal Chemistry Letters. 15, 15, p. 3565-3567 3 p.

Research output: Contribution to journalArticle

Amphotericin B
Derivatives
Fluorination
Fluorine
Halogenation
42 Citations (Scopus)

Dominant formation of a single-length channel by amphotericin B in dimyristoylphosphatidylcholine membrane evidenced by 13C- 31P rotational echo double resonance

Matsuoka, S., Ikeuchi, H., Matsumori, N. & Murata, M., Jan 18 2005, In : Biochemistry. 44, 2, p. 704-710 7 p.

Research output: Contribution to journalArticle

Dimyristoylphosphatidylcholine
Amphotericin B
Membranes
Carbon
Experiments
48 Citations (Scopus)

Hairpin conformation of amphidinols possibly accounting for potent membrane permeabilizing activities

Houdai, T., Matsuoka, S., Morsy, N., Matsumori, N., Satake, M. & Murata, M., Mar 14 2005, In : Tetrahedron. 61, 11, p. 2795-2802 8 p.

Research output: Contribution to journalArticle

Conformations
Membranes
Polyenes
Lipid bilayers
Dinoflagellida
53 Citations (Scopus)

Isolation and structure elucidation of a new amphidinol with a truncated polyhydroxyl chain from Amphidinium klebsii

Morsy, N., Matsuoka, S., Houdai, T., Matsumori, N., Adachi, S., Murata, M., Iwashita, T. & Fujita, T., Sep 5 2005, In : Tetrahedron. 61, 36, p. 8606-8610 5 p.

Research output: Contribution to journalArticle

Polyenes
Dinoflagellida
Sulfates
Esters
Carbon
27 Citations (Scopus)

Ladder-shaped polyether compound, desulfated yessotoxin, interacts with membrane-integral α-helix peptides

Mori, M., Oishi, T., Matsuoka, S., Ujihara, S., Matsumori, N., Murata, M., Satake, M., Oshima, Y., Matsushita, N. & Aimoto, S., Sep 1 2005, In : Bioorganic and Medicinal Chemistry. 13, 17, p. 5099-5103 5 p.

Research output: Contribution to journalArticle

Polyethers
Ladders
Ciguatoxins
Membranes
Oligomers
69 Citations (Scopus)
Amino Sugars
Ergosterol
Amino sugars
Amphotericin B
Sterols
2004
16 Citations (Scopus)

Amphotericin B covalent dimers bearing a tartarate linkage

Matsumori, N., Masuda, R. & Murata, M., Dec 1 2004, In : Chemistry and Biodiversity. 1, 2, p. 346-352 7 p.

Research output: Contribution to journalArticle

Bearings (structural)
Amphotericin B
Ion Channels
Dimers
Ions
33 Citations (Scopus)

An amphotericin B-ergosterol covalent conjugate with powerful membrane permeabilizing activity

Matsumori, N., Eiraku, N., Matsuoka, S., Oishi, T., Murata, M., Aoki, T. & Ide, T., May 1 2004, In : Chemistry and Biology. 11, 5, p. 673-679 7 p.

Research output: Contribution to journalArticle

Ergosterol
Amphotericin B
Membranes
Cholesterol
Bearings (structural)
43 Citations (Scopus)

Membrane-permeabilizing activities of amphidinol 3, polyene-polyhydroxy antifungal from a marine dinoflagellate

Houdai, T., Matsuoka, S., Matsumori, N. & Murata, M., Nov 17 2004, In : Biochimica et Biophysica Acta - Biomembranes. 1667, 1, p. 91-100 10 p.

Research output: Contribution to journalArticle

Polyenes
Dinoflagellida
Membranes
Filipin
Liposomes
4 Citations (Scopus)

Synthesis and conformation of deuterated spermidine for investigating weak interaction with polyanionic biomolecules

Maruyoshi, K., Demura, T., Sagane, T., Matsumori, N., Oishi, T. & Murata, M., Jun 7 2004, In : Tetrahedron. 60, 24, p. 5163-5170 8 p.

Research output: Contribution to journalArticle

Spermidine
Biomolecules
Conformations
Polyamines
Spermine
2003
27 Citations (Scopus)

Amphotericin B-phospholipid covalent conjugates: Dependence of membrane-permeabilizing activity on acyl-chain length

Matsuoka, S., Matsumori, N. & Murata, M., Nov 21 2003, In : Organic and Biomolecular Chemistry. 1, 22, p. 3882-3884 3 p.

Research output: Contribution to journalArticle

Amphotericin B
Ion Channels
Chain length
Phospholipids
membranes