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Research Output 1990 2019

  • 4836 Citations
  • 32 h-Index
  • 124 Article
  • 16 Review article
  • 3 Comment/debate
2019

A case of acute exacerbation of chronic adrenal insufficiency due to ipilimumab treatment for advanced melanoma

Sakaguchi, C., Yano, S., Ashida, K., Wada, N., Ohe, K., Nagata, H., Matsuda, Y., Sakamoto, S., Sakamoto, R., Ohnaka, K., Uchi, H., Furue, M., Nomura, M. & Ogawa, Y., Jan 1 2019, In : American Journal of Case Reports. 20, p. 106-110 5 p.

Research output: Contribution to journalArticle

Adrenal Insufficiency
Melanoma
Therapeutics
Programmed Cell Death 1 Receptor
ipilimumab

Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout

Kawamura, Y., Nakaoka, H., Nakayama, A., Okada, Y., Yamamoto, K., Higashino, T., Sakiyama, M., Shimizu, T., Ooyama, H., Ooyama, K., Nagase, M., Hidaka, Y., Shirahama, Y., Hosomichi, K., Nishida, Y., Shimoshikiryo, I., Hishida, A., Katsuura-Kamano, S., Shimizu, S., Kawaguchi, M. & 29 others, Uemura, H., Ibusuki, R., Hara, M., Naito, M., Takao, M., Nakajima, M., Iwasawa, S., Nakashima, H., Ohnaka, K., Nakamura, T., Stiburkova, B., Merriman, T. R., Nakatochi, M., Ichihara, S., Yokota, M., Takada, T., Saitoh, T., Kamatani, Y., Takahashi, A., Arisawa, K., Takezaki, T., Tanaka, K., Wakai, K., Kubo, M., Hosoya, T., Ichida, K., Inoue, I., Shinomiya, N. & Matsuo, H., Oct 1 2019, In : Annals of the Rheumatic Diseases. 78, 10, p. 1430-1437 8 p.

Research output: Contribution to journalArticle

Open Access
Gout
Genome-Wide Association Study
Uric Acid
Genes
Crystals
2018
2 Citations (Scopus)

Effect of early treatment on physical function in daily management of rheumatoid arthritis: A 5-year longitudinal study of rheumatoid arthritis patients in the national database of rheumatic diseases in Japan

Hirata, A., Suenaga, Y., Miyamura, T., Matsui, T., Tohma, S., Suematsu, E., Ohnaka, K. & Takayanagi, R., Jan 1 2018, In : International Journal of Rheumatic Diseases. 21, 4, p. 828-835 8 p.

Research output: Contribution to journalArticle

Biological Factors
Rheumatic Diseases
Longitudinal Studies
Rheumatoid Arthritis
Japan
3 Citations (Scopus)

Genomewide association study of leisure-time exercise behavior in Japanese Adults

Hara, M., Hachiya, T., Sutoh, Y., Matsuo, K., Nishida, Y., Shimanoe, C., Tanaka, K., Shimizu, A., Ohnaka, K., Kawaguchi, T., Oze, I., Matsuda, F., Ito, H., Kawai, S., Hishida, A., Okada, R., Sasakabe, T., Hirata, A., Ibusuki, R., Nindita, Y. & 19 others, Furusyo, N., Ikezaki, H., Kuriyama, N., Ozaki, E., Mikami, H., Nakamura, Y., Suzuki, S., Hosono, A., Katsuura-Kamano, S., Arisawa, K., Kuriki, K., Endoh, K., Takashima, N., Kadota, A., Nakatochi, M., Momozawa, Y., Kubo, M., Naito, M. & Wakai, K., Dec 1 2018, In : Medicine and Science in Sports and Exercise. 50, 12, p. 2433-2441 9 p.

Research output: Contribution to journalArticle

Leisure Activities
Exercise
Single Nucleotide Polymorphism
Meta-Analysis
Linear Models
2017
2 Citations (Scopus)

Comparison of weighed food record procedures for the reference methods in two validation studies of food frequency questionnaires

Ishii, Y., Ishihara, J., Takachi, R., Shinozawac, Y., Imaeda, N., Goto, C., Wakai, K., Takahashi, T., Iso, H., Nakamura, K., Tanaka, J., Shimazu, T., Yamaji, T., Sasazuki, S., Sawada, N., Iwasaki, M., Mikami, H., Kuriki, K., Naito, M., Okamoto, N. & 13 others, Kondo, F., Hosono, S., Miyagawa, N., Ozaki, E., Katsuura-Kamano, S., Ohnaka, K., Nanri, H., Tsunematsu-Nakahata, N., Kayama, T., Kurihara, A., Kojima, S., Tanaka, H. & Tsugane, S., Jan 1 2017, In : Journal of epidemiology. 27, 7, p. 331-337 7 p.

Research output: Contribution to journalArticle

Validation Studies
Food
Portion Size
Surveys and Questionnaires
Diet Records
4 Citations (Scopus)

Effect modification of green tea on the association between rice intake and the risk of diabetes mellitus: A prospective study in Japanese men and women

Hirata, A., Ohnaka, K., Tashiro, N., Wang, Z., Kohno, M., Kiyohara, C., Kono, S. & Takayanagi, R., May 1 2017, In : Asia Pacific Journal of Clinical Nutrition. 26, 3, p. 545-555 11 p.

Research output: Contribution to journalArticle

Tea
Diabetes Mellitus
Prospective Studies
Coffee
Oryza
1 Citation (Scopus)

Genome-wide DNA methylation analysis reveals hypomethylation in the low-CpG promoter regions in lymphoblastoid cell lines

Taniguchi, I., Iwaya, C., Ohnaka, K., Shibata, H. & Yamamoto, K., Mar 4 2017, In : Human Genomics. 11, 1, 8.

Research output: Contribution to journalArticle

DNA Methylation
Genetic Promoter Regions
Methylation
Genome
Blood Cells
20 Citations (Scopus)

Isolated ACTH deficiency probably induced by autoimmune-related mechanism evoked with nivolumab

Kitajima, K., Ashida, K., Wada, N., Suetsugu, R., Takeichi, Y., Sakamoto, S., Uchi, H., Matsushima, T., Shiratsuchi, M., Ohnaka, K., Furue, M. & Nomura, M., May 1 2017, In : Japanese journal of clinical oncology. 47, 5, p. 463-466 4 p., hyx018.

Research output: Contribution to journalArticle

Adrenocorticotropic Hormone
Hydrocortisone
Melanoma
Magnetic Resonance Imaging
Anterior Pituitary Hormones
2 Citations (Scopus)

Macronutrient intakes and serum oestrogen, and interaction with polymorphisms in CYP19A1 and HSD17B1 genes: A cross-sectional study in postmenopausal Japanese women

Takagi, S., Naito, M., Kawai, S., Okada, R., Nagata, C., Hosono, S., Nishida, Y., Takashima, N., Suzuki, S., Shimoshikiryo, I., Mikami, H., Uemura, H., Kuriyama, N., Ohnaka, K., Kubo, M., Hamajima, N., Tanaka, H. & Wakai, K., Sep 28 2017, In : British Journal of Nutrition. 118, 6, p. 463-472 10 p.

Research output: Contribution to journalArticle

Estrogens
Cross-Sectional Studies
Serum
Genes
Unsaturated Fatty Acids
7 Citations (Scopus)

Matrix metalloproteinase 9 gene polymorphisms are associated with a multiple family history of gastric cancer

The Japan Multi-institutional Collaborative Cohort Study Group, Mar 1 2017, In : Gastric Cancer. 20, 2, p. 246-253 8 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Genes
Tissue Inhibitor of Metalloproteinases
Odds Ratio
Matrix Metalloproteinase Inhibitors
5 Citations (Scopus)

The fine-scale genetic structure and evolution of the Japanese population

Japanese Genome Variation Consortium, Nov 2017, In : PloS one. 12, 11, e0185487.

Research output: Contribution to journalArticle

Molecular Evolution
Genetic Structures
Polymorphism
Principal component analysis
Statistical methods
2016
2 Citations (Scopus)

Dehydroepiandrosterone(DHEA)and bone metabolism

Ohnaka, K., Jul 1 2016, In : Clinical calcium. 26, 7, p. 987-993 7 p.

Research output: Contribution to journalReview article

Dehydroepiandrosterone
Bone and Bones
Androgens
Osteoporosis
Aromatase
2 Citations (Scopus)

Effects of self-reported calorie restriction on correlations between SIRT1 polymorphisms and body mass index and long-term weight change

Higashibata, T., Wakai, K., Naito, M., Morita, E., Hishida, A., Hamajima, N., Hara, M., Suzuki, S., Hosono, S., Takashima, N., Ohnaka, K., Takada, A., Mikami, H., Watanabe, Y., Uemura, H., Kubo, M. & Tanaka, H., Dec 5 2016, In : Gene. 594, 1, p. 16-22 7 p.

Research output: Contribution to journalArticle

Body Mass Index
Weights and Measures
Alleles
Japan
Cohort Studies
10 Citations (Scopus)

Eplerenone improves carotid intima-media thickness (IMT) in patients with primary aldosteronism

Matsuda, Y., Kawate, H., Matsuzaki, C., Sakamoto, R., Shibue, K., Ohnaka, K., Anzai, K., Nomura, M. & Takayanagi, R., Mar 31 2016, In : Endocrine Journal. 63, 3, p. 249-255 7 p.

Research output: Contribution to journalArticle

Carotid Intima-Media Thickness
Hyperaldosteronism
Adrenalectomy
Aldosterone
Blood Vessels
27 Citations (Scopus)

Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference

Wen, W., Kato, N., Hwang, J. Y., Guo, X., Tabara, Y., Li, H., Dorajoo, R., Yang, X., Tsai, F. J., Li, S., Wu, Y., Wu, T., Kim, S., Guo, X., Liang, J., Shungin, D., Adair, L. S., Akiyama, K., Allison, M., Cai, Q. & 56 others, Chang, L. C., Chen, C. H., Chen, Y. T., Cho, Y. S., Choi, B. Y., Gao, Y., Go, M. J., Gu, D., Han, B. G., He, M., Hixson, J. E., Hu, Y., Huang, T., Isono, M., Jung, K. J., Kang, D., Kim, Y. J., Kita, Y., Lee, J., Lee, N. R., Lee, J., Wang, Y., Liu, J. J., Long, J., Moon, S., Nakamura, Y., Nakatochi, M., Ohnaka, K., Rao, D., Shi, J., Sull, J. W., Tan, A., Ueshima, H., Wu, C., Xiang, Y. B., Yamamoto, K., Yao, J., Ye, X., Yokota, M., Zhang, X., Zheng, Y., Qi, L., Rotter, J. I., Jee, S. H., Lin, D., Mohlke, K. L., He, J., Mo, Z., Wu, J. Y., Tai, E. S., Lin, X., Miki, T., Kim, B. J., Takeuchi, F., Zheng, W. & Shu, X. O., Jan 20 2016, In : Scientific reports. 6, 17985.

Research output: Contribution to journalArticle

Waist-Hip Ratio
Genome-Wide Association Study
Waist Circumference
Abdominal Obesity
Body Mass Index
5 Citations (Scopus)

High-sensitivity C-reactive protein and risks of all-cause and cause-specific mortality in a Japanese population

Nisa, H., Hirata, A., Kohno, M., Kiyohara, C. & Ohnaka, K., Jun 1 2016, In : Asian Pacific Journal of Cancer Prevention. 17, 5, p. 2643-2648 6 p.

Research output: Contribution to journalArticle

C-Reactive Protein
Mortality
Population
Cause of Death
Cardiovascular Diseases
9 Citations (Scopus)

Variant of the clock circadian regulator (CLOCK) gene and related haplotypes are associated with the prevalence of type 2 diabetes in the Japanese population

for the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group, Sep 1 2016, In : Journal of Diabetes. 8, 5, p. 667-676 10 p.

Research output: Contribution to journalArticle

Circadian Clocks
Regulator Genes
Type 2 Diabetes Mellitus
Haplotypes
Population
2015
9 Citations (Scopus)
ARNTL Transcription Factors
Type 2 Diabetes Mellitus
Japan
Cohort Studies
Cross-Sectional Studies
6 Citations (Scopus)
Aspartate Aminotransferases
Interleukin-6
Japan
Cohort Studies
Cross-Sectional Studies
10 Citations (Scopus)

Associations between Vitamin D receptor (VDR) gene polymorphisms and colorectal cancer risk and effect modifications of dietary calcium and Vitamin D in a Japanese population

Takeshige, N., Yin, G., Ohnaka, K., Kono, S., Ueki, T., Tanaka, M., Maehara, Y., Okamura, T., Ikejiri, K., Maekawa, T., Yasunami, Y., Takenaka, K., Ichimiya, H. & Terasaka, R., Jan 1 2015, In : Asian Pacific Journal of Cancer Prevention. 16, 5, p. 2019-2026 8 p.

Research output: Contribution to journalArticle

Dietary Calcium
Calcitriol Receptors
Vitamin D
Colorectal Neoplasms
Population
6 Citations (Scopus)

Epigenome-wide association study suggests that SNPs in the promoter region of RETN influence plasma resistin level via effects on DNA methylation at neighbouring sites

Nakatochi, M., Ichihara, S., Yamamoto, K., Ohnaka, K., Kato, Y., Yokota, S., Hirashiki, A., Naruse, K., Asano, H., Izawa, H., Matsubara, T. & Yokota, M., Sep 24 2015, In : Diabetologia. 58, 12, p. 2781-2790 10 p.

Research output: Contribution to journalArticle

Resistin
DNA Methylation
Genetic Promoter Regions
Single Nucleotide Polymorphism
Genes
3 Citations (Scopus)

Mapping the genetic diversity of HLA haplotypes in the Japanese populations

Japanese Genome Variation Consortium, Dec 9 2015, In : Scientific reports. 5, 17855.

Research output: Contribution to journalArticle

Haplotypes
Japan
Major Histocompatibility Complex
Population
Human Genome
4 Citations (Scopus)

Polymorphisms in CYP19A1, HSD17B1 and HSD17B2 genes and serum sex hormone level among postmenopausal Japanese women

Hosono, S., Ito, H., Oze, I., Higaki, Y., Morita, E., Takashima, N., Suzuki, S., Shimatani, K., Mikami, H., Ohnaka, K., Ozaki, E., Katsuura-Kamano, S., Kubo, M., Nagata, C., Naito, M., Hamajima, N. & Tanaka, H., Dec 2015, In : Maturitas. 82, 4, p. 394-401 8 p.

Research output: Contribution to journalArticle

Gonadal Steroid Hormones
Polymorphism
Genes
Single Nucleotide Polymorphism
Serum
140 Citations (Scopus)

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

Kato, N., Loh, M., Takeuchi, F., Verweij, N., Wang, X., Zhang, W., NKelly, T., Saleheen, D., Lehne, B., Leach, I. M., Drong, A. W., Abbott, J., Wahl, S., Tan, S. T., Scott, W. R., Campanella, G., Chadeau-Hyam, M., Afzal, U., Ahluwalia, T. S., Bonder, M. J. & 225 others, Chen, P., Dehghan, A., Edwards, T. L., Esko, T., Go, M. J., Harris, S. E., Hartiala, J., Kasela, S., Kasturiratne, A., Khor, C. C., Kleber, M. E., Li, H., Mok, Z. Y., Nakatochi, M., Sapari, N. S., Saxena, R., Stewart, A. F. R., Stolk, L., Tabara, Y., Teh, A. L., Wu, Y., Wu, J. Y., Zhang, Y., Aits, I., Da Silva Couto Alves, A., Das, S., Dorajoo, R., CHopewell, J., Kim, Y. K., WKoivula, R., Luan, JA., Lyytikäinen, L. P., NNguyen, Q., Pereira, M. A., Postmus, I., TRaitakari, O., Scannell Bryan, M., Scott, R. A., Sorice, R., Tragante, V., Traglia, M., White, J., Yamamoto, K., Zhang, Y., Adair, L. S., Ahmed, A., Akiyama, K., Asif, R., Aung, T., Barroso, I., Bjonnes, A., Braun, T. R., Cai, H., Chang, L. C., Chen, C. H., Cheng, C. Y., Chong, Y. S., Collins, R., Courtney, R., Davies, G., Delgado, G., Do, L. D., Doevendans, P. A., Gansevoort, R. T., Gao, Y. T., Grammer, T. B., Grarup, N., Grewal, J., Gu, D., SWander, G., Hartikainen, A. L., Hazen, S. L., He, J., Heng, C. K., Hixso, E. J. A., Hofman, A., Hsu, C., Huang, W., Husemoen, L. L. N., Hwang, J. Y., Ichihara, S., Igase, M., Isono, M., Justesen, J. M., Katsuya, T., GKibriya, M., Kim, Y. J., Kishimoto, M., Koh, W. P., Kohara, K., Kumari, M., Kwek, K., Lee, N. R., Lee, J., Liao, J., Lieb, W., Liewald, D. C. M., Matsubara, T., Matsushita, Y., Meitinger, T., Mihailov, E., Milani, L., Mills, R., Mononen, N., Müller-Nurasyid, M., Nabika, T., Nakashima, E., Ng, H. K., Nikus, K., Nutile, T., Ohkubo, T., Ohnaka, K., Parish, S., Paternoster, L., Peng, H., Peters, A., TPham, S., Pinidiyapathirage, M. J., Rahman, M., Rakugi, H., Rolandsson, O., Rozario, M. A., Ruggiero, D., Sala, C. F., Sarju, R., Shimokawa, K., Snieder, H., SparsØ, T., Spiering, W., Starr, J. M., Stott, D. J., OStram, D., Sugiyama, T., Szymczak, S., Tang, W. H. W., Tong, L., Trompet, S., Turjanmaa, V., Ueshima, H., Uitterlinden, A. G., Umemura, S., Vaarasmaki, M., Dam, R. M., Van Gilst, W. H., Van Veldhuisen, D. J., Viikari, J. S., Waldenberger, M., Wang, Y., Wang, A., Wilson, R., Wong, T. Y., Xiang, Y. B., Yamaguchi, S., Ye, X., Young, R. D., Young, T. L., Yuan, J. M., Zhou, X., Asselbergs, F. W., Ciullo, M., Clarke, R., Deloukas, P., Franke, A., Paul, W. F., Franks, S., Friedlander, Y., Gross, M. D., Guo, Z., Hansen, T., Jarvelin, M. R., JØrgensen, T., Jukema, J. W., Kähönen, M., Kajio, H., Kivimaki, M., Lee, J. Y., Lehtimäki, T., Linneberg, A., Miki, T., Pedersen, O., Samani, N. J., SØrensen, T. I. A., Takayanagi, R., Toniolo, D., Ahsan, H., Allayee, H., Chen, Y. T., Danesh, J., Deary, I. J., Franco, O. H., Franke, L., THeijman, B., Holbrook, J. D., Isaacs, A., Kim, B. J., Lin, X., Liu, J., März, W., Metspalu, A., Mohlke, K. L., Sangher, K., Harambir, D., Shu, X. O., Van Meurs, J. B. J., Vithana, E., Wickremasinghe, A. R., Wijmenga, C., Wolffenbuttel, B. H. W., Yokota, M., Zheng, W., Zhu, D., Vineis, P., Kyrtopoulos, S. A., Kleinjans, J. C. S., McCarthy, M. I., Soong, R., Gieger, C., Scott, J., Teo, Y. Y., He, J., Elliott, P., Tai, E. S., Van Der Harst, P., Kooner, J. S. & Chambers, J. C., Nov 1 2015, In : Nature genetics. 47, 11, p. 1282-1293 12 p.

Research output: Contribution to journalArticle

Genetic Loci
Genome-Wide Association Study
DNA Methylation
Blood Pressure
Single Nucleotide Polymorphism
2014
7 Citations (Scopus)

A polymorphism near MC4R gene (rs17782313) is associated with serum triglyceride levels in the general Japanese population: The J-MICC Study

Katsuura-Kamano, S., Uemura, H., Arisawa, K., Yamaguchi, M., Hamajima, N., Wakai, K., Okada, R., Suzuki, S., Taguchi, N., Kita, Y., Ohnaka, K., Kairupan, T. S., Matsui, D., Oze, I., Mikami, H., Kubo, M. & Tanaka, H., Jan 1 2014, In : Endocrine. 47, 1, p. 81-89 9 p.

Research output: Contribution to journalArticle

Receptor, Melanocortin, Type 4
Japan
Triglycerides
Cohort Studies
Body Mass Index
4 Citations (Scopus)

Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose level in the Japanese general population

Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group, Jan 1 2014, In : Journal of epidemiology. 24, 5, p. 379-384 6 p.

Research output: Contribution to journalArticle

Fasting
Body Mass Index
Genotype
Glucose
Blood Glucose
5 Citations (Scopus)

GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese individuals: Data from the J-MICC Study

Hishida, A., Takashima, N., Turin, T. C., Kawai, S., Wakai, K., Hamajima, N., Hosono, S., Nishida, Y., Suzuki, S., Nakahata, N., Mikami, H., Ohnaka, K., Matsui, D., Katsuura-Kamano, S., Kubo, M., Tanaka, H. & Kita, Y., Apr 2014, In : Journal of Nephrology. 27, 2, p. 143-149 7 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Genotype
Japan
Smoking
Odds Ratio
528 Citations (Scopus)

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Mahajan, A., Go, M. J., Zhang, W., Below, J. E., Gaulton, K. J., Ferreira, T., Horikoshi, M., Johnson, A. D., Ng, M. C. Y., Prokopenko, I., Saleheen, D., Wang, X., Zeggini, E., Abecasis, G. R., Adair, L. S., Almgren, P., Atalay, M., Aung, T., Baldassarre, D., Balkau, B. & 312 others, Bao, Y., Barnett, A. H., Barroso, I., Basit, A., Been, L. F., Beilby, J., Bell, G. I., Benediktsson, R., Bergman, R. N., OBoehm, B., Boerwinkle, E., Bonnycastle, L. L., Burtt, N., Cai, Q., Campbell, H., Carey, J., Cauchi, S., Caulfield, M., Chan, J. C. N., Chang, L. C., Chang, T. J., Chang, Y. C., Charpentier, G., Chen, C. H., Chen, H., Chen, Y. T., Chia, K. S., Chidambaram, M., Chines, P. S., Cho, N. H., Cho, Y. M., Chuang, L. M., Collins, F. S., Cornelis, M. C., Couper, D. J., Crenshaw, A. T., Van Dam, R. M., Danesh, J., Das, D., De Faire, U., Dedoussis, G., Deloukas, P., Dimas, A. S., Dina, C., Doney, A. S. F., Donnelly, P. J., Dorkhan, M., Van Duijn, C., Dupuis, J., Edkins, S., Elliott, P., Emilsson, V., Erbel, R., Eriksson, J. G., Escobedo, J., Esko, T., Eury, E., Florez, J. C., Fontanillas, P., Forouhi, N. G., Forsen, T., Fox, C., Fraser, R. M., Frayling, T. M., Froguel, P., Frossard, P., Gao, Y., Gertow, K., Gieger, C., Gigante, B., Grallert, H., Grant, G. B., Groop, L. C., Groves, C. J., Grundberg, E., Guiducci, C., Hamsten, A., Han, B. G., Hara, K., Hassanali, N., Hattersley, A. T., Hayward, C., Hedman, A. K., Herder, C., Hofman, A., Holmen, O. L., Hovingh, K., Hreidarsson, A. B., Hu, C., Hu, F. B., Hui, J., Humphries, S. E., Hunt, S. E., Hunter, D. J., Hveem, K., Hydrie, Z. I., Ikegami, H., Illig, T., Ingelsson, E., Islam, M., Isomaa, B., Jackson, A. U., Jafar, T., James, A., Jia, W., Jöckel, K. H., Jonsson, A., Jowett, J. B. M., Kadowaki, T., Kang, H. M., Kanoni, S., Kao, W. H. L., Kathiresan, S., Kato, N., Katulanda, P., Keinanen-Kiukaanniemi, S. M., Kelly, A. M., Khan, H., Khaw, K. T., Khor, C. C., Kim, H. L., Kim, S., Kim, Y. J., Kinnunen, L., Klopp, N., Kong, A., Korpi-Hyövälti, E., Kowlessur, S., Kraft, P., Kravic, J., Kristensen, M. M., Krithika, S., Kumar, A., Kumate, J., Kuusisto, J., Kwak, S. H., Laakso, M., Lagou, V., Lakka, T. A., Langenberg, C., Langford, C., Lawrence, R., Leander, K., Lee, J. M., Lee, N. R., Li, M., Li, X., Li, Y., Liang, J., Liju, S., Lim, W. Y., Lind, L., Lindgren, C. M., Lindholm, E., Liu, C. T., Liu, J. J., Lobbens, S., Long, J., Loos, R. J. F., Lu, W., Luan, J., Lyssenko, V., WMa, R. C., Maeda, S., Mägi, R., Männistö, S., Matthews, D. R., Meigs, J. B., Melander, O., Metspalu, A., Meyer, J., Mirza, G., Mihailov, E., Moebus, S., Mohan, V., Mohlke, K. L., Morris, A. D., WMühleisen, T., Müller-Nurasyid, M., Musk, B., Nakamura, J., Nakashima, E., Navarro, P., Ng, P. K., Nica, A. C., Nilsson, P. M., Njølstad, I., Nöthen, M. M., Ohnaka, K., Ong, T. H., Owen, K. R., Palmer, C. N. A., Pankow, J. S., Park, K. S., Parkin, M., Pechlivanis, S., Pedersen, N. L., Peltonen, L., Perry, J. R. B., Peters, A., Pinidiyapathirage, J. M., Platou, C. G. P., Potter, S., Price, J. F., Qi, L., Radha, V., Rallidis, L., Rasheed, A., Rathmann, W., Rauramaa, R., Raychaudhuri, S., Rayner, N. W., Rees, S. D., Rehnberg, E., Ripatti, S., Robertson, N., Roden, M., Rossin, E. J., Rudan, I., Rybin, D., Saaristo, T. E., Salomaa, V., Saltevo, J., Samuel, M., KSanghera, D., Saramies, J., Scott, J., Scott, L. J., Scott, R. A., Segrè, A. V., Sehmi, J., Sennblad, B., Shah, N., Shah, S., Shera, A. S., Shu, X. O., Shuldiner, A. R., Sigurosson, G., Sijbrands, E., Silveira, A., Sim, X., Sivapalaratnam, S., Small, K. S., So, W. Y., Stančáková, A., Stefansson, K., Steinbach, G., Steinthorsdottir, V., Stirrups, K., Strawbridge, R. J., Stringham, H. M., Sun, Q., Suo, C., Syvänen, A. C., Takayanagi, R., Takeuchi, F., Tay, W. T., Teslovich, T. M., Thorand, B., Thorleifsson, G., Thorsteinsdottir, U., Tikkanen, E., Trakalo, J., Tremoli, E., Trip, M. D., Tsai, F. J., Tuomi, T., Tuomilehto, J., Uitterlinden, A. G., Valladares-Salgado, A., Vedantam, S., Veglia, F., Voight, B. F., Wang, C., Wareham, N. J., Wennauer, R., Wickremasinghe, A. R., Wilsgaard, T., Wilson, J. F., Wiltshire, S., Winckler, W., Wong, T. Y., Wood, A. R., Wu, J. Y., Wu, Y., Yamamoto, K., Yamauchi, T., Yang, M., Yengo, L., Yokota, M., Young, R., Zabaneh, D., Zhang, F., Zhang, R., Zheng, W., Zimmet, P. Z., Altshuler, D., Bowden, D. W., Cho, Y. S., Cox, N. J., Cruz, M., Hanis, C. L., Kooner, J., Lee, J. Y., Seielstad, M., Teo, Y. Y., Boehnke, M., Parra, E. J., Chambers, J. C., Tai, E. S., McCarthy, M. I. & Morris, A. P., Mar 2014, In : Nature genetics. 46, 3, p. 234-244 11 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Meta-Analysis
Genome
Genome-Wide Association Study
Single Nucleotide Polymorphism
11 Citations (Scopus)

Long-term study of subclinical Cushing’s syndrome shows high prevalence of extra-adrenal malignancy in patients with functioning bilateral adrenal tumors

Kawate, H., Kohno, M., Yayoi, M., Akehi, Y., Tanabe, M., Horiuchi, T., Ohnaka, K., Nomura, M., Yanase, T. & Takayanagi, R., Jan 1 2014, In : Endocrine Journal. 61, 12, p. 1205-1212 8 p.

Research output: Contribution to journalArticle

Glandular and Epithelial Neoplasms
Cushing Syndrome
Neoplasms
Hydrocortisone
Diabetes Mellitus
35 Citations (Scopus)

Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians

Chen, P., Takeuchi, F., Lee, J. Y., Li, H., Wu, J. Y., Liang, J., Long, J., Tabara, Y., Goodarzi, M. O., Pereira, M. A., Kim, Y. J., Go, M. J., Stram, D. O., Vithana, E., Khor, C. C., Liu, J., Liao, J., Ye, X., Wang, Y., Lu, L. & 50 others, Young, T. L., Lee, J., Thai, A. C., Cheng, C. Y., Van Dam, R. M., Friedlander, Y., Heng, C. K., Koh, W. P., Chen, C. H., Chang, L. C., Pan, W. H., Qi, B., Isono, M., Zheng, W., Cai, Q., Gao, Y., Yamamoto, K., Ohnaka, K., Takayanagi, R., Kita, Y., Ueshima, H., Hsiung, C. A., Cui, J., Sheu, W. H. H., Rotter, J. I., Chen, Y. D. I., Hsu, C., Okada, Y., Kubo, M., Takahashi, A., Tanaka, T., Van Rooij, F. J. A., Ganesh, S. K., Huang, J., Huang, T., Yuan, J., Hwang, J. Y., Gross, M. D., Assimes, T. L., Miki, T., Shu, X. O., Qi, L., Chen, Y. T., Lin, X., Aung, T., Wong, T. Y., Teo, Y. Y., Kim, B. J., Kato, N. & Tai, E. S., Jul 2014, In : Diabetes. 63, 7, p. 2551-2562 12 p.

Research output: Contribution to journalArticle

Glycosylated Hemoglobin A
Hemoglobins
Genome-Wide Association Study
Meta-Analysis
Glucose
3 Citations (Scopus)

Perioperative sequential monitoring of hemodynamic parameters in patients with pheochromocytoma using the Non-Invasive Cardiac System (NICaS)

Matsuda, Y., Kawate, H., Shimada, S., Matsuzaki, C., Nagata, H., Adachi, M., Ohnaka, K., Nomura, M. & Takayanagi, R., 2014, In : Endocrine Journal. 61, 6, p. 571-575 5 p.

Research output: Contribution to journalArticle

Pheochromocytoma
Blood Volume
Cardiac Output
Hemodynamics
Serum Albumin
3 Citations (Scopus)

Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese - Cross-sectional data from the J-MICC study

Hishida, A., Wakai, K., Naito, M., Suma, S., Sasakabe, T., Hamajima, N., Hosono, S., Horita, M., Turin, T. C., Suzuki, S., Kairupan, T. S., Mikami, H., Ohnaka, K., Watanabe, I., Uemura, H., Kubo, M. & Tanaka, H., Oct 14 2014, In : Lipids in Health and Disease. 13, 1, 162.

Research output: Contribution to journalArticle

Polymorphism
Chronic Renal Insufficiency
Lipid Metabolism
Japan
Cohort Studies
8 Citations (Scopus)

Sugars, sucrose and colorectal cancer risk: the Fukuoka colorectal cancer study

Wang, Z., Uchida, K., Ohnaka, K., Morita, M., Toyomura, K., Kono, S., Ueki, T., Tanaka, M., Kakeji, Y., Maehara, Y., Okamura, T., Ikejiri, K., Futami, K., Maekawa, T., Yasunami, Y., Takenaka, K., Ichimiya, H. & Terasaka, R., May 2014, In : Scandinavian Journal of Gastroenterology. 49, 5, p. 581-588 8 p.

Research output: Contribution to journalArticle

Sucrose
Colorectal Neoplasms
Logistic Models
Alcohols
Portion Size
2013

A potential improvement of rheumatoid arthritis in a patient treated with liraglutide for glucocorticoid-induced diabetes

Kohno, M., Nomura, M., Abe, I., Matsumura, Y., Matsuda, Y., Adachi, M., Kawate, H., Ohnaka, K., Horiuchi, T. & Takayanagi, R., Mar 1 2013, In : Journal of the Japan Diabetes Society. 56, 3, p. 179-184 6 p.

Research output: Contribution to journalArticle

Glucocorticoids
Rheumatoid Arthritis
glimepiride
Prednisolone
Insulin
8 Citations (Scopus)

Behavioral and clinical correlates of serum bilirubin concentrations in Japanese men and women

Tanaka, M., Budhathoki, S., Hirata, A., Morita, M., Kono, S., Adachi, M., Kawate, H., Ohnaka, K. & Takayanagi, R., Oct 4 2013, In : BMC Endocrine Disorders. 13, 39.

Research output: Contribution to journalArticle

Bilirubin
Serum
Coffee
Smoking
HDL Cholesterol
5 Citations (Scopus)

Coffee consumption, serum γ-glutamyltransferase, and glucose tolerance status in middle-aged Japanese men

Hiramatsu, T., Tajima, O., Uezono, K., Tabata, S., Abe, H., Ohnaka, K. & Kono, S., Jun 1 2013, In : Clinical Chemistry and Laboratory Medicine. 51, 6, p. 1233-1239 7 p.

Research output: Contribution to journalArticle

Coffee
Medical problems
Glucose
Serum
Type 2 Diabetes Mellitus
10 Citations (Scopus)

CYP1A1, GSTM1, GSTT1 and NQO1 polymorphisms and colorectal adenomas in japanese men

Hamachi, T., Tajima, O., Uezono, K., Tabata, S., Abe, H., Ohnaka, K. & Kono, S., Jul 7 2013, In : World Journal of Gastroenterology. 19, 25, p. 4023-4030 8 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP1A1
Adenoma
Genotype
Smoking
Genetic Polymorphisms
36 Citations (Scopus)

Dietary polyphenols and colorectal cancer risk: The Fukuoka colorectal cancer study

Wang, Z. J., Ohnaka, K., Morita, M., Toyomura, K., Kono, S., Ueki, T., Tanaka, M., Kakeji, Y., Maehara, Y., Okamura, T., Ikejiri, K., Futami, K., Maekawa, T., Yasunami, Y., Takenaka, K., Ichimiya, H. & Terasaka, R., May 7 2013, In : World Journal of Gastroenterology. 19, 17, p. 2683-2690 8 p.

Research output: Contribution to journalArticle

Polyphenols
Colorectal Neoplasms
Coffee
Colonic Neoplasms
Odds Ratio
17 Citations (Scopus)

Folate-related nutrients, genetic polymorphisms, and colorectal cancer risk: The Fukuoka colorectal cancer study

Morita, M., Yin, G., Yoshimitsu, S. I., Ohnaka, K., Toyomura, K., Kono, S., Ueki, T., Tanaka, M., Kakeji, Y., Maehara, Y., Okamura, T., Ikejiri, K., Futami, K., Maekawa, T., Yasunami, Y., Takenaka, K., Ichimiya, H. & Terasaka, R., 2013, In : Asian Pacific Journal of Cancer Prevention. 14, 11, p. 6249-6256 8 p.

Research output: Contribution to journalArticle

Genetic Polymorphisms
Folic Acid
Colorectal Neoplasms
Food
Vitamin B 6
6 Citations (Scopus)

Gene-gene combination effect and interactions among ABCA1, APOA1, SR-B1, and CETP polymorphisms for serum high-density lipoprotein-cholesterol in the japanese population

Nakamura, A., Niimura, H., Kuwabara, K., Takezaki, T., Morita, E., Wakai, K., Hamajima, N., Nishida, Y., Turin, T. C., Suzuki, S., Ohnaka, K., Uemura, H., Ozaki, E., Hosono, S., Mikami, H., Kubo, M. & Tanaka, H., Dec 20 2013, In : PloS one. 8, 12, e82046.

Research output: Contribution to journalArticle

Polymorphism
high density lipoprotein cholesterol
HDL Cholesterol
Genes
genetic polymorphism
10 Citations (Scopus)

Genetic impact on Uric acid concentration and hyperuricemia in the Japanese population

Takeuchi, F., Yamamoto, K., Isono, M., Katsuya, T., Akiyama, K., Ohnaka, K., Rakugi, H., Yamori, Y., Ogihara, T., Takayanagi, R. & Kato, N., May 3 2013, In : Journal of atherosclerosis and thrombosis. 20, 4, p. 351-367 17 p.

Research output: Contribution to journalArticle

Hyperuricemia
Uric Acid
Population
Polymorphism
Single Nucleotide Polymorphism
5 Citations (Scopus)

Genome-wide association study of genetic factors related to confectionery intake: Potential roles of the ADIPOQ gene

Wakai, K., Matsuo, K., Matsuda, F., Yamada, R., Takahashi, M., Kawaguchi, T., Yatabe, Y., Ito, H., Hosono, S., Tajima, K., Naito, M., Morita, E., Yin, G., Sakamoto, T., Takashima, N., Suzuki, S., Nakahata, N., Mikami, H., Ohnaka, K., Watanabe, Y. & 4 others, Arisawa, K., Kubo, M., Hamajima, N. & Tanaka, H., Nov 1 2013, In : Obesity. 21, 11, p. 2413-2419 7 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Single Nucleotide Polymorphism
Genes
Cancer Care Facilities
Adipokines
13 Citations (Scopus)

Microsomal epoxide hydrolase polymorphisms, cigarette smoking, and risk of colorectal cancer: The Fukuoka colorectal cancer study

Nisa, H., Budhathoki, S., Morita, M., Toyomura, K., Nagano, J., Ohnaka, K., Kono, S., Ueki, T., Tanaka, M., Kakeji, Y., Maehara, Y., Okamura, T., Ikejiri, K., Futami, K., Maekawa, T., Yasunami, Y., Takenaka, K., Ichimiya, H. & Terasaka, R., Aug 1 2013, In : Molecular Carcinogenesis. 52, 8, p. 619-626 8 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Colorectal Neoplasms
Smoking
Phenotype
Exons
3 Citations (Scopus)

Polymorphisms in PPAR genes (PPARD, PPARG, and PPARGC1A) and the risk of chronic kidney disease in Japanese: Cross-sectional data from the J-MICC study

Hishida, A., Wakai, K., Naito, M., Tamura, T., Kawai, S., Hamajima, N., Oze, I., Imaizumi, T., Turin, T. C., Suzuki, S., Kheradmand, M., Mikami, H., Ohnaka, K., Watanabe, Y., Arisawa, K., Kubo, M. & Tanaka, H., Dec 6 2013, In : PPAR Research. 980471.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Chronic Renal Insufficiency
Japan
Cohort Studies
Genes
5 Citations (Scopus)

Reduced arterial stiffness in patients with acromegaly: Noninvasive assessment by the cardio-ankle vascular index (CAVI)

Matsuda, Y., Kawate, H., Matsuzaki, C., Sakamoto, R., Abe, I., Shibue, K., Kohno, M., Adachi, M., Ohnaka, K., Nomura, M. & Takayanagi, R., Feb 13 2013, In : Endocrine Journal. 60, 1, p. 29-36 8 p.

Research output: Contribution to journalArticle

Vascular Stiffness
Acromegaly
Ankle
Blood Vessels
Insulin-Like Growth Factor I
2012

[Series: Clinical study from Japan and its reflections; Kyushu University Fukuoka Cohort Study].

Ohnaka, K., Inoguchi, T., Kono, S. & Takayanagi, R., Apr 10 2012, In : Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 101, 4, p. 1141-1144 4 p.

Research output: Contribution to journalArticle

Life Style
Japan
Cohort Studies
Clinical Studies
4 Citations (Scopus)

Association between the catechol-O-methyltransferase (rs4680: Val158Met) polymorphism and serum alanine aminotransferase activity

Hiyoshi, M., Uemura, H., Arisawa, K., Nakamoto, M., Hishida, A., Okada, R., Matsuo, K., Kita, Y., Niimura, H., Kuriyama, N., Nanri, H., Ohnaka, K., Suzuki, S., Mikami, H., Kubo, M., Tanaka, H. & Hamajima, N., Apr 1 2012, In : Gene. 496, 2, p. 97-102 6 p.

Research output: Contribution to journalArticle

Catechol O-Methyltransferase
Alanine Transaminase
Homozygote
Serum
Liver
22 Citations (Scopus)

Associations of apolipoprotein A5 (APOA5), glucokinase (GCK) and glucokinase regulatory protein (GCKR) polymorphisms and lifestyle factors with the risk of dyslipidemia and dysglycemia in Japanese - A cross-sectional data from the J-MICC study

Hishida, A., Morita, E., Naito, M., Okada, R., Wakai, K., Matsuo, K., Nakamura, K., Takashima, N., Suzuki, S., Takezaki, T., Mikami, H., Keizo, O., Watanabe, Y., Uemura, H., Kubo, M., Tanaka, H. & Hamajima, N., Sep 6 2012, In : Endocrine Journal. 59, 7, p. 589-599 11 p.

Research output: Contribution to journalArticle

Glucokinase
Apolipoproteins
Dyslipidemias
Life Style
Fasting
4 Citations (Scopus)

Behavioral and clinical correlates of high-sensitivity C-reactive protein in Japanese men and women

Hirata, A., Ohnaka, K., Morita, M., Toyomura, K., Kono, S., Yamamoto, K., Adachi, M., Kawate, H. & Takayanagi, R., Oct 1 2012, In : Clinical Chemistry and Laboratory Medicine. 50, 8, p. 1469-1476 8 p.

Research output: Contribution to journalArticle

C-Reactive Protein
Body Mass Index
Smoking
Medical problems
Type 2 Diabetes Mellitus
16 Citations (Scopus)

Deletion of CDKAL1 Affects High-Fat Diet-Induced Fat Accumulation and Glucose-Stimulated Insulin Secretion in Mice, Indicating Relevance to Diabetes

Okamura, T., Yanobu-Takanashi, R., Takeuchi, F., Isono, M., Akiyama, K., Shimizu, Y., Goto, M., Liang, Y. Q., Yamamoto, K., Katsuya, T., Fujioka, A., Ohnaka, K., Takayanagi, R., Ogihara, T., Yamori, Y. & Kato, N., Nov 16 2012, In : PloS one. 7, 11, e49055.

Research output: Contribution to journalArticle

insulin secretion
High Fat Diet
high fat diet
Nutrition
Medical problems