• 1015 Citations
  • 16 h-Index
19962020

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Article
2020

Oxidative-stress-driven mutagenesis in the small intestine of the gpt delta mouse induced by oral administration of potassium bromate

Aoki, Y., Taniguchi, Y., Matsumoto, M., Matsumoto, M., Ohno, M., Masumura, K., Sasaki, S., Tsuzuki, T., Yamamoto, M. & Nohmi, T., Feb 1 2020, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 850-851, 503136.

Research output: Contribution to journalArticle

2019

Spontaneous de novo germline mutations in humans and mice: rates, spectra, causes and consequences

Ohno, M., Jan 1 2019, In : Genes and Genetic Systems. 94, 1, p. 13-22 10 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2015

Germline mutation rates and the long-term phenotypic effects of mutation accumulation in wild-type laboratory mice and mutator mice

Uchimura, A., Higuchi, M., Minakuchi, Y., Ohno, M., Toyoda, A., Fujiyama, A., Miura, I., Wakana, S., Nishino, J. & Yagi, T., Aug 1 2015, In : Genome Research. 25, 8, p. 1125-1134 10 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

PSMC5, a 19S proteasomal ATPase, regulates cocaine action in the nucleus accumbens

Ohnishi, Y. H., Ohnishi, Y. N., Nakamura, T., Ohno, M., Kennedy, P. J., Yasuyuki, O., Nishi, A., Neve, R., Tsuzuki, T. & Nestler, E. J., May 11 2015, In : PloS one. 10, 5, e0126710.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2014

8-Oxoguanine causes spontaneous de novo germline mutations in mice

Ohno, M., Sakumi, K., Fukumura, R., Furuichi, M., Iwasaki, Y., Hokama, M., Ikemura, T., Tsuzuki, T., Gondo, Y. & Nakabeppu, Y., Apr 1 2014, In : Scientific reports. 4, 4689.

Research output: Contribution to journalArticle

76 Citations (Scopus)
2013

Mismatch repair deficient mice show susceptibility to oxidative stress-induced intestinal carcinogenesis.

Piao, J., Nakatsu, Y., Ohno, M., Taguchi, K. I. & Tsuzuki, T., 2013, In : International journal of biological sciences. 10, 1, p. 73-79 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Nature of nontargeted radiation effects observed during fractionated irradiation-induced thymic lymphomagenesis in mice

Tsuji, H., Ishii-Ohba, H., Shiomi, T., Shiomi, N., Katsube, T., Mori, M., Nenoi, M., Ohno, M., Yoshimura, D., Oka, S., Nakabeppu, Y., Tatsumi, K., Muto, M. & Sado, T., May 1 2013, In : Journal of radiation research. 54, 3, p. 453-466 14 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2010

NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals

Abolhassani, N., Iyama, T., Tsuchimoto, D., Sakumi, K., Ohno, M., Behmanesh, M. & Nakabeppu, Y., Jan 15 2010, In : Nucleic acids research. 38, 9, p. 2891-2903 13 p., gkp1250.

Research output: Contribution to journalArticle

41 Citations (Scopus)
2009

Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

Fujita, K., Seike, T., Yutsudo, N., Ohno, M., Yamada, H., Yamaguchi, H., Sakumi, K., Yamakawa, Y., Kido, M. A., Takaki, A., Katafuchi, T., Tanaka, Y., Nakabeppu, Y. & Noda, M., Sep 30 2009, In : PloS one. 4, 9, e7247.

Research output: Contribution to journalArticle

121 Citations (Scopus)
2008

Altered gene expression profiles and higher frequency of spontaneous DNA strand breaks in APEX2-null thymus

Dan, Y., Ohta, Y., Tsuchimoto, D., Mizuki, O., Ide, Y., Sami, M., Kanda, T., Kunihiko, S. & Nakabeppu, Y., Sep 1 2008, In : DNA Repair. 7, 9, p. 1437-1454 18 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death

Ichikawa, J., Tsuchimoto, D., Oka, S., Ohno, M., Furuichi, M., Sakumi, K. & Nakabeppu, Y., Mar 1 2008, In : DNA Repair. 7, 3, p. 418-430 13 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs

Oka, S., Ohno, M., Tsuchimoto, D., Sakumi, K., Furuichi, M. & Nakabeppu, Y., Jan 23 2008, In : EMBO Journal. 27, 2, p. 421-432 12 p.

Research output: Contribution to journalArticle

149 Citations (Scopus)
2006
57 Citations (Scopus)
57 Citations (Scopus)
2005

Selective induction of ΔFosB in the brain after transient forebrain ischemia accompanied by an increased expression of galectin-1, and the implication of ΔFosB and galectin-1 in neuroprotection and neurogenesis

Kurushima, H., Ohno, M., Miura, T., Nakamura, T. Y., Horie, H., Kadoya, T., Ooboshi, H., Kitazono, T., Ibayashi, S., Iida, M. & Nakabeppu, Y., Aug 1 2005, In : Cell Death and Differentiation. 12, 8, p. 1078-1096 19 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2004

Growth retardation and dyslymphopoiesis accompanied by G2/M arrest in APEX2-null mice

Ide, Y., Tsuchimoto, D., Tominaga, Y., Nakashima, M., Watanabe, T., Sakumi, K., Ohno, M. & Nakabeppu, Y., Dec 15 2004, In : Blood. 104, 13, p. 4097-4103 7 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2003

An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress

Yoshimura, D., Sakumi, K., Ohno, M., Sakai, Y., Furuichi, M., Iwai, S. & Nakabeppu, Y., Sep 26 2003, In : Journal of Biological Chemistry. 278, 39, p. 37965-37973 9 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)

Mammalian Elongin A is not essential for cell viability but is required for proper cell cycle progression with limited alteration of gene expression

Yamazaki, K., Aso, T., Ohnishi, Y., Mizuki, O., Tamura, K., Shuin, T., Kitajima, S. & Nakabeppu, Y., Apr 11 2003, In : Journal of Biological Chemistry. 278, 15, p. 13585-13589 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2002

Triplex-forming DNAs in the human interphase nucleus visualized in situ by polypurine/polypyrimidine DNA probes and antitriplex antibodies

Ohno, M., Fukagawa, T., Lee, J. S. & Ikemura, T., Sep 2002, In : Chromosoma. 111, 3, p. 201-213 13 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)
2001
27 Citations (Scopus)
1999

Position-independent human β-globin gene expression mediated by a recombinant adeno-associated virus vector carrying the chicken β-globin insulator

Inoue, T., Yamaza, H., Sakai, Y., Mizuno, S., Mizuki, O., Hamasaki, N. & Fukumaki, Y., Jan 1 1999, In : Journal of Human Genetics. 44, 3, p. 152-162 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)