• 3886 Citations
  • 31 h-Index
19952020

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2013

A minimally invasive and simple screening test for detection of pancreatic ductal adenocarcinoma using biomarkers in duodenal juice

Mori, Y., Ohtsuka, T., Kono, H., Nagayoshi, Y., Ideno, N., Aso, T., Kozono, S., Ohuchida, K., Takahata, S., Nakamura, M., Mizumoto, K. & Tanaka, M., Mar 1 2013, In : Pancreas. 42, 2, p. 187-192 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Combination therapy of portal vein resection and adjuvant gemcitabine improved prognosis of advanced pancreatic cancer

Nakamura, M., Kayashima, T., Fujiwara, K., Nagayoshi, Y., Kono, H., Ohtsuka, T., Takahata, S., Mizumoto, K. & Tanaka, M., Jan 1 2013, In : Hepato-gastroenterology. 60, 121, p. 354-357 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Extensive distal pancreatectomy for pancreatic tumor

Nakamura, M., Ohtsuka, T., Nakashima, H., Nagayoshi, Y., Kono, H., Tsutsumi, K., Takahata, S. & Tanaka, M., Jan 1 2013, In : Anticancer research. 33, 1, p. 267-270 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

High expression of microRNA-155 is associated with the aggressive malignant behavior of gallbladder carcinoma.

Kono, H., Nakamura, M., Ohtsuka, T., Nagayoshi, Y., Mori, Y., Takahata, S., Aishima, S. & Tanaka, M., Jul 2013, In : Oncology reports. 30, 1, p. 17-24 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Hypoxia enhances the interaction between pancreatic stellate cells and cancer cells via increased secretion of connective tissue growth factor

Eguchi, D., Ikenaga, N., Ohuchida, K., Kozono, S., Cui, L., Fujiwara, K., Fujino, M., Ohtsuka, T., Mizumoto, K. & Tanaka, M., May 15 2013, In : Journal of Surgical Research. 181, 2, p. 225-233 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Intraductal papillary mucinous neoplasms of the pancreas with distinct pancreatic ductal adenocarcinomas are frequently of gastric subtype

Ideno, N., Ohtsuka, T., Kono, H., Fujiwara, K., Oda, Y., Aishima, S., Ito, T., Ishigami, K., Tokunaga, S., Ohuchida, K., Takahata, S., Nakamura, M., Mizumoto, K. & Tanaka, M., Jul 1 2013, In : Annals of surgery. 258, 1, p. 141-151 11 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Kindlin-1 expression is involved in migration and invasion of pancreatic cancer

Mahawithitwong, P., Ohuchida, K., Ikenaga, N., Fujita, H., Zhao, M., Kozono, S., Shindo, K., Ohtsuka, T., Aishima, S., Mizumoto, K. & Tanaka, M., Apr 1 2013, In : International journal of oncology. 42, 4, p. 1360-1366 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Kindlin-2 expression in peritumoral stroma is associated with poor prognosis in pancreatic ductal adenocarcinoma

Mahawithitwong, P., Ohuchida, K., Ikenaga, N., Fujita, H., Zhao, M., Kozono, S., Shindo, K., Ohtsuka, T., Mizumoto, K. & Tanaka, M., May 1 2013, In : Pancreas. 42, 4, p. 663-669 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

MAL2 expression predicts distant metastasis and short survival in pancreatic cancer

Eguchi, D., Ohuchida, K., Kozono, S., Ikenaga, N., Shindo, K., Cui, L., Fujiwara, K., Akagawa, S., Ohtsuka, T., Takahata, S., Tokunaga, S., Mizumoto, K. & Tanaka, M., Sep 1 2013, In : Surgery (United States). 154, 3, p. 573-582 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Migratory activity of CD105+ pancreatic cancer cells is strongly enhanced by pancreatic stellate cells

Fujiwara, K., Ohuchida, K., Ohtsuka, T., Mizumoto, K., Shindo, K., Ikenaga, N., Cui, L., Takahata, S., Aishima, S. & Tanaka, M., Nov 1 2013, In : Pancreas. 42, 8, p. 1283-1290 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Role of endoscopic retrograde pancreatography for early detection of pancreatic ductal adenocarcinoma concomitant with intraductal papillary mucinous neoplasm of the pancreas

Ohtsuka, T., Ideno, N., Aso, T., Nagayoshi, Y., Kono, H., Mori, Y., Takahata, S., Oda, Y., Aishima, S., Igarashi, H., Ito, T., Ishigami, K., Nakamura, M., Mizumoto, K. & Tanaka, M., Mar 1 2013, In : Journal of Hepato-Biliary-Pancreatic Sciences. 20, 3, p. 356-361 6 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

S100A4 mRNA expression level is a predictor of radioresistance of pancreatic cancer cells

Kozono, S., Ohuchida, K., Ohtsuka, T., Cui, L., Eguchi, D., Fujiwara, K., Zhao, M., Mizumoto, K. & Tanaka, M., Oct 1 2013, In : Oncology reports. 30, 4, p. 1601-1608 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Small-sized, flat-type invasive branch duct intraductal papillary mucinous neoplasm: A case report

Shindo, K., Ueda, J., Aishima, S., Aso, A., Ohtsuka, T., Takahata, S., Ishigami, K., Oda, Y. & Tanaka, M., Sep 1 2013, In : Case Reports in Gastroenterology. 7, 3, p. 449-454 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Surgery for chronic pancreatitis decreases the risk for pancreatic cancer: A multicenter retrospective analysis

Ueda, J., Tanaka, M., Ohtsuka, T., Tokunaga, S. & Shimosegawa, T., Mar 1 2013, In : Surgery (United States). 153, 3, p. 357-364 8 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Surgical treatment of gastroentero-pancreatic neuroendocrine tumor

Ohtsuka, T., Takahata, S., Ueda, J., Ueki, T., Nagai, E., Mizumoto, K., Shimizu, S. & Tanaka, M., Jul 2013, In : Japanese Journal of Cancer and Chemotherapy. 40, 7, p. 843-846 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Unresectable pancreatic ductal adenocarcinoma in the remnant pancreas diagnosed during every-6-month surveillance after resection of branch duct intraductal papillary mucinous neoplasm: A case report

Tamura, K., Ohtsuka, T., Ideno, N., Aso, T., Kono, H., Nagayoshi, Y., Shindo, K., Ushijima, Y., Ueda, J., Takahata, S., Ito, T., Oda, Y., Mizumoto, K. & Tanaka, M., Jul 17 2013, In : Journal of the Pancreas. 14, 4, p. 450-453 4 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2012

Analysis of lymph node metastasis in pancreatic neuroendocrine tumors (PNETs) based on the tumor size and hormonal production

Tsutsumi, K., Ohtsuka, T., Mori, Y., Fujino, M., Yasui, T., Aishima, S., Takahata, S., Nakamura, M., Ito, T. & Tanaka, M., Jun 1 2012, In : Journal of gastroenterology. 47, 6, p. 678-685 8 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

An increase in the number of predictive factors augments the likelihood of malignancy in branch duct intraductal papillary mucinous neoplasm of the pancreas

Ohtsuka, T., Kono, H., Nagayoshi, Y., Mori, Y., Tsutsumi, K., Sadakari, Y., Takahata, S., Morimatsu, K., Aishima, S., Igarashi, H., Ito, T., Ishigami, K., Nakamura, M., Mizumoto, K. & Tanaka, M., Jan 1 2012, In : Surgery. 151, 1, p. 76-83 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

CD271+ Subpopulation of Pancreatic Stellate Cells Correlates with Prognosis of Pancreatic Cancer and Is Regulated by Interaction with Cancer Cells

Fujiwara, K., Ohuchida, K., Mizumoto, K., Shindo, K., Eguchi, D., Kozono, S., Ikenaga, N., Ohtsuka, T., Takahata, S., Aishima, S. & Tanaka, M., Dec 27 2012, In : PloS one. 7, 12, e52682.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Claudin-4 expression predicts survival in pancreatic ductal adenocarcinoma

Tsutsumi, K., Sato, N., Tanabe, R., Mizumoto, K., Morimatsu, K., Kayashima, T., Fujita, H., Ohuchida, K., Ohtsuka, T., Takahata, S., Nakamura, M. & Tanaka, M., Jul 1 2012, In : Annals of Surgical Oncology. 19, SUPPL. 3, p. S491-S499

Research output: Contribution to journalArticle

27 Citations (Scopus)

Diagnostic significance of a dilated orifice of the duodenal papilla in intraductal papillary mucinous neoplasm of the pancreas

Aso, T., Ohtsuka, T., Ideno, N., Kono, H., Nagayoshi, Y., Mori, Y., Ohuchida, K., Ueda, J., Takahata, S., Morimatsu, K., Aishima, S., Igarashi, H., Ito, T., Ishigami, K., Mizumoto, K. & Tanaka, M., Aug 1 2012, In : Gastrointestinal endoscopy. 76, 2, p. 313-320 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Different incretin responses after pancreatoduodenectomy and distal pancreatectomy

Mori, Y., Ohtsuka, T., Tsutsumi, K., Yasui, T., Ueda, J., Takahata, S., Nakamura, M. & Tanaka, M., Apr 1 2012, In : Pancreas. 41, 3, p. 455-460 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Follow-up study after resection of intraductal papillary mucinous neoplasm of the pancreas; special references to the multifocal lesions and development of ductal carcinoma in the remnant pancreas

Ohtsuka, T., Kono, H., Tanabe, R., Nagayoshi, Y., Mori, Y., Sadakari, Y., Takahata, S., Oda, Y., Aishima, S., Igarashi, H., Ito, T., Ishigami, K., Nakamura, M., Mizumoto, K. & Tanaka, M., Jul 1 2012, In : American Journal of Surgery. 204, 1, p. 44-48 5 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Is cholecystectomy necessary after endoscopic treatment of bile duct stones in patients older than 80 years of age?

Yasui, T., Takahata, S., Kono, H., Nagayoshi, Y., Mori, Y., Tsutsumi, K., Sadakari, Y., Ohtsuka, T., Nakamura, M. & Tanaka, M., Jan 1 2012, In : Journal of gastroenterology. 47, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Management strategy for multifocal branch duct intraductal papillary mucinous neoplasms of the pancreas

Mori, Y., Ohtsuka, T., Kono, H., Ideno, N., Aso, T., Nagayoshi, Y., Takahata, S., Nakamura, M., Ishigami, K., Aishima, S., Oda, Y. & Tanaka, M., Oct 1 2012, In : Pancreas. 41, 7, p. 1008-1012 5 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Manometric evidence of earlier recovery of fasting gastric motility after antecolic duodenojejunostomy than after retrocolic duodenojejunostomy following PPPD

Tanabe, R., Ohtsuka, T., Miyatake, E., Kawamoto, M., Nakamura, M., Takahata, S. & Tanaka, M., Sep 1 2012, In : Hepato-gastroenterology. 59, 118, p. 1981-1985 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

MicroRNA-10a is overexpressed in human pancreatic cancer and involved in its invasiveness partially via suppression of the HOXA1 gene

Ohuchida, K., Mizumoto, K., Lin, C., Yamaguchi, H., Ohtsuka, T., Sato, N., Toma, H., Nakamura, M., Nagai, E., Hashizume, M. & Tanaka, M., Jul 1 2012, In : Annals of Surgical Oncology. 19, 7, p. 2394-2402 9 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Pancreatic cancer cells enhance the ability of collagen internalization during epithelial-mesenchymal transition

Ikenaga, N., Ohuchida, K., Mizumoto, K., Akagawa, S., Fujiwara, K., Eguchi, D., Kozono, S., Ohtsuka, T., Takahata, S. & Tanaka, M., Jul 5 2012, In : PloS one. 7, 7, e40434.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Targeting the hedgehog signaling pathway with interacting peptides to Patched-1

Nakamura, M., Tanaka, H., Nagayoshi, Y., Nakashima, H., Tsutsumi, K., Takao, O., Takahata, S., Tanaka, M. & Okada, H., Apr 2012, In : Journal of Gastroenterology. 47, 4, p. 452-460 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

The risk of lymph node metastasis in mucosal gastric carcinoma: Especially for a mixture of differentiated and undifferentiated adenocarcinoma

Nakata, K., Nagai, E., Miyasaka, Y., Ohuchida, K., Ohtsuka, T., Toma, H., Hirahashi, M., Aishima, S., Oda, Y. & Tanaka, M., Sep 1 2012, In : Hepato-gastroenterology. 59, 118, p. 1855-1858 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Type II congenital biliary dilation (biliary diverticulum) with pancreaticobiliary maljunction successfully treated by laparoscopic surgery: Report of a case

Kono, H., Ohtsuka, T., Fujino, M., Ideno, N., Aso, T., Nagasyoshi, Y., Mori, Y., Takahata, S., Nakamura, M., Ueki, T. & Tanaka, M., Feb 1 2012, In : Clinical Journal of Gastroenterology. 5, 1, p. 88-92 5 p.

Research output: Contribution to journalArticle

2011

Adenoviral therapy is more effective in gemcitabine-resistant pancreatic cancer than in gemcitabine-sensitive cells

Yasui, T., Ohuchida, K., Zhao, M., Cui, L., Onimaru, M., Egami, T., Fujita, H., Ohtsuka, T., Mizumoto, K., Matsumoto, K. & Tanaka, M., Apr 1 2011, In : Anticancer research. 31, 4, p. 1279-1287 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A history of acute pancreatitis in intraductal papillary mucinous neoplasms of the pancreas is a potential predictive factor for malignant papillary subtype

Tsutsumi, K., Ohtsuka, T., Oda, Y., Sadakari, Y., Mori, Y., Aishima, S., Takahata, S., Nakamura, M., Mizumoto, K. & Tanaka, M., Mar 2011, In : Pancreatology. 10, 6, p. 707-712 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Expression of claudin-4 (CLDN4) mRNA in intraductal papillary mucinous neoplasms of the pancreas

Tsutsumi, K., Sato, N., Cui, L., Mizumoto, K., Sadakari, Y., Fujita, H., Ohuchida, K., Ohtsuka, T., Takahata, S. & Tanaka, M., Apr 1 2011, In : Modern Pathology. 24, 4, p. 533-541 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Factors in intraductal papillary mucinous neoplasms of the pancreas predictive of lymph node metastasis

Kobayashi, K., Sadakari, Y., Ohtsuka, T., Takahata, S., Nakamura, M., Mizumoto, K. & Tanaka, M., Mar 2011, In : Pancreatology. 10, 6, p. 720-725 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

High EGFR mRNA expression is a prognostic factor for reduced survival in pancreatic cancer after gemcitabine-based adjuvant chemotherapy

Fujita, H., Ohchida, K., Mizumoto, K., Itaba, S., Ito, T., Nakata, K., Yu, J., Kayashima, T., Hayashi, A., Souzaki, R., Tajiri, T., Onimaru, M., Manabe, T., OHTSuka, T. & Tanaka, M., Mar 1 2011, In : International journal of oncology. 38, 3, p. 629-641 13 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Lateral approach for laparoscopic splenic vessel-preserving distal pancreatectomy

Nakamura, M., Nagayoshi, Y., Kono, H., Mori, Y., Ohtsuka, T., Takahata, S., Shimizu, S. & Tanaka, M., Aug 1 2011, In : Surgery. 150, 2, p. 326-331 6 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

MicroRNA-10b is overexpressed in pancreatic cancer, promotes its invasiveness, and correlates with a poor prognosis

Nakata, K., Ohuchida, K., Mizumoto, K., Kayashima, T., Ikenaga, N., Sakai, H., Lin, C., Fujita, H., Otsuka, T., Aishima, S., Nagai, E., Oda, Y. & Tanaka, M., Nov 1 2011, In : Surgery. 150, 5, p. 916-922 7 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)

MicroRNA expression as a predictive marker for gemcitabine response after surgical resection of pancreatic cancer

Ohuchida, K., Mizumoto, K., Kayashima, T., Fujita, H., Moriyama, T., Ohtsuka, T., Ueda, J., Nagai, E., Hashizume, M. & Tanaka, M., Aug 1 2011, In : Annals of Surgical Oncology. 18, 8, p. 2381-2387 7 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Predicting the chemosensitivity of pancreatic cancer cells by quantifying the expression levels of genes associated with the metabolism of gemcitabine and 5-fluorouracil

Kurata, N., Fujita, H., Ohuchida, K., Mizumoto, K., Mahawithitwong, P., Sakai, H., Onimaru, M., Manabe, T., Ohtsuka, T. & Tanaka, M., Aug 1 2011, In : International journal of oncology. 39, 2, p. 473-482 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Single-incision laparoscopy-assisted surgery for bowel obstruction: Report of three cases

Ohtsuka, T., Nagai, E., Toma, H., Ohuchida, K., Takanami, H., Odate, S., Eguchi, D., Ueki, T., Shimizu, S. & Tanaka, M., Nov 1 2011, In : Surgery today. 41, 11, p. 1519-1523 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Tumor-stroma interactions reduce the efficacy of adenoviral therapy through the HGF-MET pathway

Yasui, T., Ohuchida, K., Zhao, M., Onimaru, M., Egami, T., Fujita, H., Ohtsuka, T., Mizumoto, K. & Tanaka, M., Feb 1 2011, In : Cancer Science. 102, 2, p. 484-491 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2010

Gene expression levels as predictive markers of outcome in pancreatic cancer after gemcitabine-based adjuvant chemotherapy

Fujita, H., Ohuchida, K., Mizumoto, K., Itaba, S., Ito, T., Nakata, K., Yu, J., Kayashima, T., Souzaki, R., Tajiri, T., Manabe, T., Ohtsuka, T. & Tanaka, M., Oct 2010, In : Neoplasia. 12, 10, p. 807-817 11 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)
70 Citations (Scopus)

MicroRNA expression analyses in preoperative pancreatic juice samples of pancreatic ductal adenocarcinoma

Sadakari, Y., Ohtsuka, T., Ohuchida, K., Tsutsumi, K., Takahata, S., Nakamura, M., Mizumoto, K. & Tanaka, M., Nov 1 2010, In : Journal of the Pancreas. 11, 6, p. 587-592 6 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Multifocal pancreatic ductal adenocarcinomas concomitant with intraductal papillary mucinous neoplasms of the pancreas detected by intraoperative pancreatic juice cytology. A case report

Mori, Y., Ohtsuka, T., Tsutsumi, K., Yasui, T., Sadakari, Y., Ueda, J., Takahata, S., Nakamura, M. & Tanaka, M., Jul 2010, In : Journal of the Pancreas. 11, 4, p. 389-392 4 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

α-Smooth muscle actin expressing stroma promotes an aggressive tumor biology in pancreatic ductal adenocarcinoma

Fujita, H., Ohuchida, K., Mizumoto, K., Nakata, K., Yu, J., Kayashima, T., Cui, L., Manabe, T., Ohtsuka, T. & Tanaka, M., Nov 1 2010, In : Pancreas. 39, 8, p. 1254-1262 9 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)
2009

A case of unresectable hilar bile duct cancer responding to chemo-radiotherapy by gemcitabine

Kohya, N., Hashiguchi, K., Yakabe, T., Miyoshi, A., Ohtsuka, T., Kitahara, K. & Miyazaki, K., Oct 2009, In : Japanese Journal of Cancer and Chemotherapy. 36, 10, p. 1753-1755 3 p.

Research output: Contribution to journalArticle

A long-time survivor of alpha-fetoprotein-producing gastric cancer successfully treated by fluoropyrimidine-based chemotherapy: A case study

Hiraki, M., Sato, S., Kai, K., Ohtsuka, T., Kohya, N., Kitajima, Y., Nakafusa, Y., Tokunaga, O. & Miyazaki, K., Oct 1 2009, In : Clinical Journal of Gastroenterology. 2, 5, p. 331-337 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Complete response obtained with first-line therapy as S-1, followed by second-line 5′-DFUR plus paclitaxel therapy in a patient with multiple liver and lymphnode metastases from gastric cancer

Kitajima, Y., Yakabe, T., Ohtsuka, T., Tanaka, M., Sato, S., Nakafusa, Y. & Miyazaki, K., May 2009, In : Japanese Journal of Cancer and Chemotherapy. 36, 5, p. 851-854 4 p.

Research output: Contribution to journalArticle