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Research Output 2011 2019

  • 73 Citations
  • 5 h-Index
  • 14 Article
  • 1 Review article
2019

Ep 4 receptor-associated protein regulates gluconeogenesis in the liver and is associated with hyperglycemia in diabetic mice

Higuchi, S., Fujikawa, R., Nakatsuji, M., Yasui, M., Ikedo, T., Nagata, M., Mishima, K., Irie, K., Matsumoto, M., Yokode, M. & Minami, M., Mar 1 2019, In : American Journal of Physiology - Endocrinology and Metabolism. 316, 3, p. E410-E417

Research output: Contribution to journalArticle

Gluconeogenesis
Hyperglycemia
Liver
Hepatocytes
Proteins

Sequential Inward Bending of Arterial Bifurcations is Associated with Intracranial Aneurysm Formation

Ikedo, T., Kataoka, H., Minami, M., Hayashi, K., Miyata, T., Nagata, M., Fujikawa, R., Yokode, M., Imai, H., Matsuda, T. & Miyamoto, S., Sep 1 2019, In : World Neurosurgery. 129, p. e361-e366

Research output: Contribution to journalArticle

Intracranial Aneurysm
Arteries
Blood Vessels
Macrophages
Magnetic Resonance Imaging
2018
1 Citation (Scopus)

Imaging mass spectroscopy delineates the thinned and thickened walls of intracranial aneurysms

Ikedo, T., Minami, M., Kataoka, H., Hayashi, K., Nagata, M., Fujikawa, R., Yamazaki, F., Setou, M., Yokode, M. & Miyamoto, S., Jan 1 2018, In : Biochemical and Biophysical Research Communications. 495, 1, p. 332-338 7 p.

Research output: Contribution to journalArticle

Intracranial Aneurysm
Muscle
Mass Spectrometry
Smooth Muscle Myocytes
Spectroscopy
2 Citations (Scopus)

The Japanese Angelica acutiloba root and yokukansan increase hippocampal acetylcholine level, prevent apoptosis and improve memory in a rat model of repeated cerebral ischemia

Nogami-Hara, A., Nagao, M., Takasaki, K., Egashira, N., Fujikawa, R., Kubota, K., Watanabe, T., Katsurabayashi, S., Hatip, F. B., Hatip-Al-Khatib, I. & Iwasaki, K., Mar 25 2018, In : Journal of Ethnopharmacology. 214, p. 190-196 7 p.

Research output: Contribution to journalArticle

Angelica
Brain Ischemia
Acetylcholine
Apoptosis
Neuroprotective Agents
2017
1 Citation (Scopus)

Behavioral abnormalities and reduced norepinephrine in EP4 receptor-associated protein (EPRAP)-deficient mice

Fujikawa, R., Higuchi, S., Ikedo, T., Nagata, M., Hayashi, K., Yang, T., Miyata, T., Yokode, M. & Minami, M., Apr 29 2017, In : Biochemical and Biophysical Research Communications. 486, 2, p. 584-588 5 p.

Research output: Contribution to journalArticle

Norepinephrine
Proteins
Inbred C57BL Mouse
Brain
Startle Reflex
1 Citation (Scopus)

Deficiency in EP4 Receptor–Associated Protein Ameliorates Abnormal Anxiety-Like Behavior and Brain Inflammation in a Mouse Model of Alzheimer Disease

Fujikawa, R., Higuchi, S., Nakatsuji, M., Yasui, M., Ikedo, T., Nagata, M., Hayashi, K., Yokode, M. & Minami, M., Aug 2017, In : American Journal of Pathology. 187, 8, p. 1848-1854 7 p.

Research output: Contribution to journalArticle

Encephalitis
Alzheimer Disease
Anxiety
Proteins
Microglia
12 Citations (Scopus)

Dipeptidyl Peptidase-4 Inhibitor Anagliptin Prevents Intracranial Aneurysm Growth by Suppressing Macrophage Infiltration and Activation

Ikedo, T., Minami, M., Kataoka, H., Hayashi, K., Nagata, M., Fujikawa, R., Higuchi, S., Yasui, M., Aoki, T., Fukuda, M., Yokode, M. & Miyamoto, S., Jun 19 2017, In : Journal of the American Heart Association. 6, 6

Research output: Contribution to journalArticle

Dipeptidyl-Peptidase IV Inhibitors
Macrophage Activation
Intracranial Aneurysm
Mitogen-Activated Protein Kinase 7
Growth

EPRAP: A key regulator of inflammation

Fujikawa, R., Higuchi, S., Nakatsuji, M., Yasui, M., Yokode, M. & Minami, M., Jan 1 2017, In : Folia Pharmacologica Japonica. 150, 2, p. 114-115 2 p.

Research output: Contribution to journalReview article

Inflammation
2016
4 Citations (Scopus)

EP4 receptor-associated protein in macrophages protects against bleomycin-induced pulmonary inflammation in mice

Higuchi, S., Fujikawa, R., Ikedo, T., Hayashi, K., Yasui, M., Nagata, M., Nakatsuji, M., Yokode, M. & Minami, M., Dec 1 2016, In : Journal of Immunology. 197, 11, p. 4436-4443 8 p.

Research output: Contribution to journalArticle

Bleomycin
Pneumonia
Macrophages
Proteins
Embryonic Structures
4 Citations (Scopus)

EP4 Receptor-Associated Protein in Microglia Promotes Inflammation in the Brain

Fujikawa, R., Higuchi, S., Nakatsuji, M., Yasui, M., Ikedo, T., Nagata, M., Yokode, M. & Minami, M., Aug 1 2016, In : American Journal of Pathology. 186, 8, p. 1982-1988 7 p.

Research output: Contribution to journalArticle

Microglia
Encephalitis
Proteins
Lipopolysaccharides
Protein Deficiency
2015
12 Citations (Scopus)

EP4 Receptor–Associated Protein in Macrophages Ameliorates Colitis and Colitis-Associated Tumorigenesis

Nakatsuji, M., Minami, M., Seno, H., Yasui, M., Komekado, H., Higuchi, S., Fujikawa, R., Nakanishi, Y., Fukuda, A., Kawada, K., Sakai, Y., Kita, T., Libby, P., Ikeuchi, H., Yokode, M. & Chiba, T., Jan 1 2015, In : PLoS genetics. 11, 10, e1005542.

Research output: Contribution to journalArticle

Dextran Sulfate
colitis
sodium sulfate
Colitis
dextran
3 Citations (Scopus)

Expression of vasohibin-1 in human carotid atherosclerotic plaque

Fukumitsu, R., Minami, M., Yoshida, K., Nagata, M., Yasui, M., Higuchi, S., Fujikawa, R., Ikedo, T., Yamagata, S., Sato, Y., Arai, H., Yokode, M. & Miyamoto, S., Sep 18 2015, In : Journal of atherosclerosis and thrombosis. 22, 9, p. 942-948 7 p.

Research output: Contribution to journalArticle

Endothelial cells
Atherosclerotic Plaques
Microvessels
Biomarkers
Endothelial Cells
10 Citations (Scopus)

The prostaglandin E2 receptor EP4 regulates obesity-related inflammation and insulin sensitivity

Yasui, M., Tamura, Y., Minami, M., Higuchi, S., Fujikawa, R., Ikedo, T., Nagata, M., Arai, H., Murayama, T. & Yokode, M., Aug 26 2015, In : PloS one. 10, 8, e0136304.

Research output: Contribution to journalArticle

Prostaglandin Receptors
Macrophages
Dinoprostone
insulin resistance
prostaglandins
2013
8 Citations (Scopus)

Effect of yokukansan on memory disturbance in an animal model of cerebrovascular dementia

Nogami, A., Takasaki, K., Kubota, K., Yamaguchi, K., Kawasaki, C., Nakamura, K., Fujikawa, R., Uchida, N., Katsurabayashi, S., Mishima, K., Nishimura, R., Fujiwara, M. & Iwasaki, K., Jan 1 2013, In : Journal of Traditional Medicines. 30, 4, p. 164-175 12 p.

Research output: Contribution to journalArticle

Dementia
Animal Models
Brain Ischemia
Ischemia
Acetylcholine
2011
15 Citations (Scopus)

Neuroprotective effects of citidine-5-diphosphocholine on impaired spatial memory in a rat model of cerebrovascular dementia

Takasaki, K., Uchida, K., Fujikawa, R., Nogami, A., Nakamura, K., Kawasaki, C., Yamaguchi, K., Morita, M., Morishita, K., Kubota, K., Katsurabayashi, S., Mishima, K., Fujiwara, M. & Iwasaki, K., Jun 24 2011, In : Journal of Pharmacological Sciences. 116, 2, p. 232-237 6 p.

Research output: Contribution to journalArticle

Cytidine Diphosphate Choline
Neuroprotective Agents
Dementia
Cell Death
Brain Ischemia