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Research Output 2002 2019

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Article
2019
1 Citation (Scopus)

A novel model for treatment of hypertrophic pachymeningitis

Cui, Y., Masaki, K., Zhang, X., Yamasaki, R., Fujii, T., Ogata, H., Hayashida, S., Yamaguchi, H., Hyodo, F., Eto, H., Koyama, S., Iinuma, K., Yonekawa, T., Matsushita, T., Yoshida, M., Yamada, K., Kawano, M., Malissen, M., Malissen, B. & Kira, J-I., Mar 1 2019, In : Annals of Clinical and Translational Neurology. 6, 3, p. 431-444 14 p.

Research output: Contribution to journalArticle

Open Access
Transforming Growth Factors
Meningitis
irbesartan
Immunoglobulin G
B-Lymphocytes

Brainstem posterior reversible encephalopathy syndrome in a case with Guillain–Barré syndrome

Yokoyama, J., Yamaguchi, H., Koge, J., Matsushita, T., Isobe, N., Yamasaki, R. & Kira, J. I., Nov 1 2019, In : Clinical and Experimental Neuroimmunology. 10, 4, p. 267-271 5 p.

Research output: Contribution to journalArticle

Posterior Leukoencephalopathy Syndrome
Brain Stem
Consciousness
Passive Immunization
Intravenous Immunoglobulins
1 Citation (Scopus)

Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis

Harada, Y., Zhang, J., Imari, K., Yamasaki, R., Ni, J., Take, H., Yamamoto, K., Kira, J-I., Nakanishi, H. & Hayashi, Y., Sep 1 2019, In : Pain. 160, 9, p. 2050-2062 13 p.

Research output: Contribution to journalArticle

Cathepsin E
Autoimmune Experimental Encephalomyelitis
Neuralgia
Neutrophils
Hyperalgesia

Cerebrospinal fluid cytokine/chemokine/growth factor profiles in idiopathic hypertrophic pachymeningitis

Zhang, X., Fujii, T., Ogata, H., Yamasaki, R., Masaki, K., Cui, Y., Matsushita, T., Isobe, N. & Kira, J-I., May 15 2019, In : Journal of Neuroimmunology. 330, p. 38-43 6 p.

Research output: Contribution to journalArticle

Nervous System Diseases
Meningitis
Chemokines
Cerebrospinal Fluid
Intercellular Signaling Peptides and Proteins
Chronic Progressive Multiple Sclerosis
Neuroimaging
Cross-Sectional Studies
Oligoclonal Bands
Colony-Stimulating Factor Receptors
Gyrus Cinguli
Alzheimer Disease
Temporal Lobe
Brain
Frontal Lobe

Higher postictal parasympathetic activity following greater ictal heart rate increase in right- than left-sided seizures

Shimmura, M., Uehara, T., Ogata, K., Shigeto, H., Maeda, T., Sakata, A., Yamasaki, R. & Kira, J-I., Aug 1 2019, In : Epilepsy and Behavior. 97, p. 161-168 8 p.

Research output: Contribution to journalArticle

Seizures
Heart Rate
Stroke
ROC Curve
Partial Epilepsy

Intractable axonal neuropathy with multifocal peripheral nerve swelling in neuromyelitis optica spectrum disorders: A case report

Mizuno, Y., Shinoda, K., Watanabe, M., Ogata, H., Isobe, N., Matsushita, T., Yamasaki, R., Tanaka, K., Koike, H., Katsuno, M. & Kira, J. I., Oct 2019, In : Multiple Sclerosis and Related Disorders. 35, p. 16-18 3 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Peripheral Nerves
Upper Extremity
Aquaporin 4
Magnetic Resonance Spectroscopy
2 Citations (Scopus)

MOG antibody disease manifesting as progressive cognitive deterioration and behavioral changes with primary central nervous system vasculitis

Baba, T., Shinoda, K., watanabe, M., Sadashima, S., Matsuse, D., Isobe, N., Yamasaki, R., Kaneko, K., Takahashi, T., Iwaki, T. & Kira, J-I., May 1 2019, In : Multiple Sclerosis and Related Disorders. 30, p. 48-50 3 p.

Research output: Contribution to journalArticle

Myelin-Oligodendrocyte Glycoprotein
Central Nervous System Vasculitis
Immunotherapy
Antibodies
Cerebrum

Novel pathogenic XK mutations in McLeod syndrome and interaction between XK protein and chorein

Urata, Y., Nakamura, M., Sasaki, N., Shiokawa, N., Nishida, Y., Arai, K., Hiwatashi, H., Yokoyama, I., Narumi, S., Terayama, Y., Murakami, T., Ugawa, Y., Sakamoto, H., Kaneko, S., Nakazawa, Y., Yamasaki, R., Sadashima, S., Sakai, T., Arai, H. & Sano, A., Jun 1 2019, In : Neurology: Genetics. 5, 3, e328.

Research output: Contribution to journalArticle

Open Access
Neuroacanthocytosis
Mutation
Proteins
Immunoblotting
Mcleod Type Neuroacanthocytosis

Serum GFAP and neurofilament light as biomarkers of disease activity and disability in NMOSD

Watanabe, M., Nakamura, Y., Michalak, Z., Isobe, N., Barro, C., Leppert, D., Matsushita, T., Hayashi, F., Yamasaki, R., Kuhle, J. & Kira, J. I., Sep 24 2019, In : Neurology. 93, 13, p. e1299-e1311

Research output: Contribution to journalArticle

Neuromyelitis Optica
Intermediate Filaments
Glial Fibrillary Acidic Protein
Blood Proteins
Biomarkers
3 Citations (Scopus)

Simultaneous MR neurography and apparent T2 mapping in brachial plexus: Evaluation of patients with chronic inflammatory demyelinating polyradiculoneuropathy

Akio, H., Togao, O., Yamashita, K., kikuchi, K., Momosaka, D., Nakatake, H., Yamasaki, R., Ogata, H., Yoneyama, M., Kira, J-I. & Honda, H., Jan 1 2019, In : Magnetic Resonance Imaging. 55, p. 112-117 6 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Brachial Plexus
Relaxation time
Healthy Volunteers
Ganglia

Spinal cord involvement by atrophy and associations with disability are different between multiple sclerosis and neuromyelitis optica spectrum disorder

Nakamura, Y., Liu, Z., Fukumoto, S., Shinoda, K., Sakoda, A., Matsushita, T., Hayashida, S., Isobe, N., Watanabe, M., Hiwatashi, A., Yamasaki, R. & Kira, J-I., Jan 1 2019, (Accepted/In press) In : European Journal of Neurology.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Multiple Sclerosis
Atrophy
Spinal Cord
Thorax

Temporal Trends in Clinical Characteristics and Door-to-Needle Time in Patients Receiving Intravenous Tissue Plasminogen Activator: A Retrospective Study of 4 Hospitals in Japan

Tanaka, K., Matsumoto, S., Yamada, T., Nagano, S., Takase, K. I., Hatano, T., Yamasaki, R. & Kira, J-I., Jan 1 2019, (Accepted/In press) In : Journal of Stroke and Cerebrovascular Diseases. 104305.

Research output: Contribution to journalArticle

Tissue Plasminogen Activator
Needles
Japan
Retrospective Studies
Stroke
2 Citations (Scopus)

Toxic myopathy with multiple deletions in mitochondrial DNA associated with long-term use of oral anti-viral drugs for hepatitis B: A case study

Fujii, T., Takase, K. I., Honda, H., Kawamura, N., Yamasaki, R., Urata, M., Uchiumi, T., Iwaki, T. & Kira, J-I., Apr 1 2019, In : Neuropathology. 39, 2, p. 162-167 6 p.

Research output: Contribution to journalArticle

Poisons
Muscular Diseases
Hepatitis B
Mitochondrial DNA
Nucleosides
2018
2 Citations (Scopus)

A comparison of brain magnetic resonance imaging lesions in multiple sclerosis by race with reference to disability progression

Nakamura, Y., Gaetano, L., Matsushita, T., Anna, A., Sprenger, T., Radue, E. W., Wuerfel, J., Bauer, L., Amann, M., Shinoda, K., Isobe, N., Yamasaki, R., Saida, T., Kappos, L. & Kira, J. I., Sep 5 2018, In : Journal of neuroinflammation. 15, 1, 255.

Research output: Contribution to journalArticle

Multiple Sclerosis
Magnetic Resonance Imaging
Brain
Atrophy
Relapsing-Remitting Multiple Sclerosis
1 Citation (Scopus)

A Novel Autoantibody against Plexin D1 in Patients with Neuropathic Pain

Fujii, T., Yamasaki, R., Iinuma, K., Tsuchimoto, D., Hayashi, Y., Saitoh, B. Y., Matsushita, T., Kido, M. A., Aishima, S., Nakanishi, H., Nakabeppu, Y. & Kira, J. I., Aug 2018, In : Annals of Neurology. 84, 2, p. 208-224 17 p.

Research output: Contribution to journalArticle

Neuralgia
Autoantibodies
Spinal Ganglia
Neurons
Unmyelinated Nerve Fibers
2 Citations (Scopus)

Association of decreased percentage of Vδ2+Vγ9+ γδ T cells with disease severity in multiple sclerosis

Maimaitijiang, G., Shinoda, K., nakamura, Y., Masaki, K., Matsushita, T., Isobe, N., Yamasaki, R., Yoshikai, Y. & Kira, J-I., Apr 10 2018, In : Frontiers in Immunology. 9, APR, 748.

Research output: Contribution to journalArticle

Multiple Sclerosis
T-Lymphocytes
Interferons
T-Cell Receptor Genes
T-Lymphocyte Gene Rearrangement
3 Citations (Scopus)

Chronic inflammatory demyelinating polyneuropathy with concurrent membranous nephropathy: An anti-paranode and podocyte protein antibody study and literature survey

Hashimoto, Y., Ogata, H., Yamasaki, R., Sasaguri, T., Ko, S., yamashita, K., Xu, Z., Matsushita, T., Tateishi, T., Akiyama, SI., Maruyama, S., Yamamoto, A. & Kira, J-I., Nov 27 2018, In : Frontiers in Neurology. 9, NOV, 00997.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Contactin 1
Podocytes
Membranous Glomerulonephritis
Antibodies
5 Citations (Scopus)
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Connexins
varespladib methyl
Astrocytes
Parkinson Disease
2 Citations (Scopus)
Connexins
Autoimmune Experimental Encephalomyelitis
Microglia
Connexin 43
Knockout Mice
Electrical Synapses
Anterior Horn Cells
Presynaptic Terminals
Amyotrophic Lateral Sclerosis
Down-Regulation

Duplication and deletion upstream of LMNB1 in autosomal dominant adult-onset leukodystrophy

Mezaki, N., Miura, T., Ogaki, K., Eriguchi, M., Mizuno, Y., Komatsu, K., Yamazaki, H., Suetsugi, N., Kawajiri, S., Yamasaki, R., Ishiguro, T., Konno, T., Nozaki, H., Kasuga, K., Okuma, Y., Kira, J-I., Hara, H., Onodera, O. & Ikeuchi, T., Dec 1 2018, In : Neurology: Genetics. 4, 6, e292.

Research output: Contribution to journalArticle

lamin B1
Leukoencephalopathies
Temporal Lobe
Reverse Transcription
Leukocytes

Elevated end-diastolic ratio of the common carotid artery due to cerebral arteriovenous malformation: Two case reports

Tanaka, K., Matsumoto, S., Yamada, T., Kondo, D., Chihara, H., Koga, M., Hatano, T., Miyagi, T., Yamasaki, R. & Kira, J-I., Aug 1 2018, In : Radiology Case Reports. 13, 4, p. 917-920 4 p.

Research output: Contribution to journalArticle

Intracranial Arteriovenous Malformations
Common Carotid Artery
Cerebral Veins
Nervous System Malformations
Headache Disorders
38 Citations (Scopus)

Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy

Ishiura, H., Doi, K., Mitsui, J., Yoshimura, J., Matsukawa, M. K., Fujiyama, A., Toyoshima, Y., Kakita, A., Takahashi, H., Suzuki, Y., Sugano, S., Qu, W., Ichikawa, K., Yurino, H., Higasa, K., Shibata, S., Mitsue, A., Tanaka, M., Ichikawa, Y., Takahashi, Y. & 47 others, Date, H., Matsukawa, T., Kanda, J., Nakamoto, F. K., Higashihara, M., Abe, K., Koike, R., Sasagawa, M., Kuroha, Y., Hasegawa, N., Kanesawa, N., Kondo, T., Hitomi, T., Tada, M., Takano, H., Saito, Y., Sanpei, K., Onodera, O., Nishizawa, M., Nakamura, M., Yasuda, T., Sakiyama, Y., Otsuka, M., Ueki, A., Kaida, K. I., Shimizu, J., Hanajima, R., Hayashi, T., Terao, Y., Inomata-Terada, S., Hamada, M., Shirota, Y., Kubota, A., Ugawa, Y., Koh, K., Takiyama, Y., Ohsawa-Yoshida, N., Ishiura, S., Yamasaki, R., Tamaoka, A., Akiyama, H., Otsuki, T., Sano, A., Ikeda, A., Goto, J., Morishita, S. & Tsuji, S., Apr 1 2018, In : Nature genetics. 50, 4, p. 581-590 10 p.

Research output: Contribution to journalArticle

Myoclonic Epilepsy
Introns
Epilepsy
Nanopores
Neurotransmitter Receptor

Hopkins syndrome following the first episode of bronchial asthma associated with enterovirus D68: A case report

Hayashi, F., Hayashi, S., Matsuse, D., Yamasaki, R., Yonekura, K. & Kira, J. I., May 23 2018, In : BMC neurology. 18, 1, 71.

Research output: Contribution to journalArticle

Enterovirus
Asthma
Respiratory Hypersensitivity
Lower Extremity
Adult Respiratory Distress Syndrome
2 Citations (Scopus)

Lumbar plexus in patients with chronic inflammatory demyelinating polyradiculoneuropathy: Evaluation with simultaneous T 2 mapping and neurography method with SHINKEI

Akio, H., Togao, O., Yamashita, K., kikuchi, K., Momosaka, D., Nakatake, H., Yamasaki, R., Ogata, H., Yoneyama, M., Kira, J-I. & Honda, H., Jan 1 2018, In : British Journal of Radiology. 91, 1092, 20180501.

Research output: Contribution to journalArticle

Lumbosacral Plexus
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Spinal Ganglia
ROC Curve
Research Ethics Committees
5 Citations (Scopus)
Antirheumatic Agents
Autoimmune Experimental Encephalomyelitis
Macrophage Activation
Microglia
Demyelinating Diseases

Oral phase dysphagia in facial onset sensory and motor neuronopathy

watanabe, M., Shiraishi, W., Yamasaki, R., Isobe, N., Sawatsubashi, M., Yasumatsu, R., Nakagawa, T. & Kira, J-I., Jun 1 2018, In : Brain and Behavior. 8, 6, e00999.

Research output: Contribution to journalArticle

Deglutition Disorders
Deglutition
Pharynx
Aspiration Pneumonia
Gastrostomy
5 Citations (Scopus)
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Antibodies
Neural Conduction
Immunotherapy
Cerebrospinal Fluid Proteins
3 Citations (Scopus)

Restoration of a conduction block after the long-term treatment of CIDP with anti-neurofascin 155 antibodies: Follow-up of a case over 23 years

Koike, H., Nishi, R., Ikeda, S., Kawagashira, Y., Iijima, M., Atsuta, N., Nakamura, T., Hirayama, M., Ogata, H., Yamasaki, R., Kira, J-I., Katsuno, M. & Sobue, G., Jan 1 2018, In : Internal Medicine. 57, 14, p. 2061-2066 6 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Hypesthesia
Antibodies
Neural Conduction
Action Potentials
10 Citations (Scopus)

Safety and efficacy of eculizumab in Guillain-Barré syndrome: a multicentre, double-blind, randomised phase 2 trial

Japanese Eculizumab Trial for GBS (JET-GBS) Study Group, Jun 2018, In : The Lancet Neurology. 17, 6, p. 519-529 11 p.

Research output: Contribution to journalArticle

Safety
Placebos
Anaphylaxis
Abscess
Japan

The contribution of glial inflammation in the pathogenesis of multiple sclerosis

Yamasaki, R. & Kira, J-I., Jan 1 2018, In : Neuro-Ophthalmology Japan. 35, 1, p. 4-10 7 p.

Research output: Contribution to journalArticle

Connexins
Neuroglia
Multiple Sclerosis
Inflammation
Recurrence
Vesicular Glutamate Transport Protein 2
STAT3 Transcription Factor
Transcriptional Activation
Glutamic Acid
Spinal Cord
2017

A case of stiff-person syndrome due to secondary adrenal insufficiency

Mizuno, Y., yamaguchi, H., Uehara, T., yamashita, K., Yamasaki, R. & Kira, J-I., Jan 1 2017, In : Clinical Neurology. 57, 6, p. 298-302 5 p.

Research output: Contribution to journalArticle

Stiff-Person Syndrome
Adrenal Insufficiency
Contracture
Hypopituitarism
Muscles

A case of superficial siderosis ameliorated after closure of dural deficit detected by MRI-CISS (constructive interference in steady state) imaging

Sakoda, A., Yamashita, K. I., Hayashida, M., Iwamoto, Y., Yamasaki, R. & Kira, J. I., Jan 1 2017, In : Clinical Neurology. 57, 4, p. 180-183 4 p.

Research output: Contribution to journalArticle

Siderosis
Dizziness
Ataxia
Headache
Cerebrospinal Fluid
2 Citations (Scopus)

A novel mutation in FGD4 causes Charcot–Marie–Tooth disease type 4H with cranial nerve involvement

Kondo, D., Shinoda, K., yamashita, K., Yamasaki, R., Hashiguchi, A., Takashima, H. & Kira, J-I., Oct 1 2017, In : Neuromuscular Disorders. 27, 10, p. 959-961 3 p.

Research output: Contribution to journalArticle

Cranial Nerves
Muscle Weakness
Scoliosis
Bilateral Hearing Loss
Facial Muscles
5 Citations (Scopus)

Apomorphine Therapy for Neuronal Insulin Resistance in a Mouse Model of Alzheimer's Disease

Nakamura, N., Ohyagi, Y., Imamura, T., Yanagihara, Y. T., Iinuma, K. M., Soejima, N., Murai, H., Yamasaki, R. & Kira, J-I., Jan 1 2017, In : Journal of Alzheimer's Disease. 58, 4, p. 1151-1161 11 p.

Research output: Contribution to journalArticle

Apomorphine
Insulin Resistance
Alzheimer Disease
Insulysin
Brain
3 Citations (Scopus)

Cerebral blood flow laterality derived from arterial spin labeling as a biomarker for assessing the disease severity of parkinson's disease

Yamashita, K., Akio, H., Togao, O., kikuchi, K., yamaguchi, H., Suzuki, Y., Kamei, R., Yamasaki, R., Kira, J-I. & Honda, H., Jun 1 2017, In : Journal of Magnetic Resonance Imaging. 45, 6, p. 1821-1826 6 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Parkinson Disease
Biomarkers
Caudate Nucleus
Globus Pallidus
Amyotrophic Lateral Sclerosis
Neuroglia
Motor Neurons
Spinal Cord
Microglia
3 Citations (Scopus)
Amyotrophic Lateral Sclerosis
Neuroglia
Motor Neurons
Spinal Cord
Microglia
1 Citation (Scopus)
Vesicular Glutamate Transport Proteins
Amino Acid Transport System X-AG
Amyotrophic Lateral Sclerosis
Motor Neurons
Neuroglia
8 Citations (Scopus)

Early and extensive spinal white matter involvement in neuromyelitis optica

Hayashida, S., Masaki, K., Yonekawa, T., Suzuki, S., Akio, H., Matsushita, T., watanabe, M., Yamasaki, R., Suenaga, T., Iwaki, T., Murai, H. & Kira, J-I., May 1 2017, In : Brain Pathology. 27, 3, p. 249-265 17 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Aquaporin 4
Spinal Cord
Horns
Antibodies
8 Citations (Scopus)
Multiple System Atrophy
Chemokines
Cerebrospinal Fluid
Case-Control Studies
Cytokines
9 Citations (Scopus)
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Ganglia
Brachial Plexus
Signal-To-Noise Ratio
Research Ethics Committees
3 Citations (Scopus)

HLA-DRB1*04:05 allele is associated with intracortical lesions on three-dimensional double inversion recovery images in Japanese patients with multiple sclerosis

Shinoda, K., Matsushita, T., Nakamura, Y., Masaki, K., Yamasaki, R., Yamaguchi, H., Togao, O., Hiwatashi, A. & Kira, J-I., May 1 2017, In : Multiple Sclerosis. p. 1352458517707067

Research output: Contribution to journalArticle

Multiple Sclerosis
Alleles
HLA-DRB1 Chains
HLA-DRB1*04 antigen
Logistic Models
9 Citations (Scopus)
Lumbosacral Plexus
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Polyneuropathies
Ganglia
ROC Curve
7 Citations (Scopus)

Markers for Guillain-Barré syndrome with poor prognosis: a multi-center study

Yamagishi, Y., Suzuki, H., Sonoo, M., Kuwabara, S., Yokota, T., Nomura, K., Chiba, A., Kaji, R., Kanda, T., Kaida, K., Ikeda, S. I., Mutoh, T., Yamasaki, R., Takashima, H., Matsui, M., Nishiyama, K., Sobue, G. & Kusunoki, S., Dec 1 2017, In : Journal of the Peripheral Nervous System. 22, 4, p. 433-439 7 p.

Research output: Contribution to journalArticle

Immunoglobulin G
Respiratory Insufficiency
Japan
Intravenous Immunoglobulins
Artificial Respiration
Common Carotid Artery
Arteries
Middle Cerebral Artery
Internal Carotid Artery
Ultrasonography
10 Citations (Scopus)

Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer’s disease

Mano, T., Nagata, K., Nonaka, T., Tarutani, A., Imamura, T., Hashimoto, T., Bannai, T., Koshi-Mano, K., Tsuchida, T., Ohtomo, R., Takahashi-Fujigasaki, J., Yamashita, S., Ohyagi, Y., Yamasaki, R., Tsuji, S., Tamaoka, A., Ikeuchi, T., Saido, T. C., Iwatsubo, T., Ushijima, T. & 3 others, Murayama, S., Hasegawa, M. & Iwata, A., Nov 7 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 45, p. E9645-E9654

Research output: Contribution to journalArticle

Epigenomics
Alzheimer Disease
Neurons
Brain
Genetic Promoter Regions