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Research Output 1989 2019

  • 653 Citations
  • 12 h-Index
  • 50 Article
  • 3 Review article
2019
1 Citation (Scopus)
Androgen Antagonists
Androgen Receptors
docetaxel
Prostatic Neoplasms
Smoking
1 Citation (Scopus)

Contractile elements and their sympathetic regulations in the pig urinary bladder: a species and regional comparative study

Mitsui, R., Lee, K., Uchiyama, A., Hayakawa, S., Kinoshita, F., Kajioka, S., Eto, M. & Hashitani, H., Jan 1 2019, (Accepted/In press) In : Cell and tissue research.

Research output: Contribution to journalArticle

Mucous Membrane
Urinary Bladder
Swine
Smooth Muscle
Tyrosine 3-Monooxygenase

Extracellular calcium stimulates osteogenic differentiation of human adipose-derived stem cells by enhancing bone morphogenetic protein-2 expression

Yanai, R., Tetsuo, F., Ito, S., Itsumi, M., Yoshizumi, J., Maki, T., Mori, Y., Kubota, Y. & Kajioka, S., Nov 2019, In : Cell Calcium. 83, 102058.

Research output: Contribution to journalArticle

Bone Morphogenetic Protein 2
Stem Cells
Calcium
Calcium-Sensing Receptors
Messenger RNA

Fetal Membrane Inflammation Induces Preterm Birth Via Toll-Like Receptor 2 in Mice With Chronic Gingivitis

Konishi, H., Urabe, S., Miyoshi, H., Teraoka, Y., Maki, T., Furusho, H., Miyauchi, M., Takata, T., Kudo, Y. & Kajioka, S., Jul 1 2019, In : Reproductive Sciences. 26, 7, p. 869-878 10 p.

Research output: Contribution to journalArticle

Extraembryonic Membranes
Gingivitis
Premature Birth
Toll-Like Receptor 2
Inflammation
1 Citation (Scopus)
Open Access
Genetic Polymorphisms
Caffeine
Healthy Volunteers
Heart Rate
Blood Pressure
2 Citations (Scopus)

Mirabegron induces relaxant effects via cAMP signaling-dependent and -independent pathways in detrusor smooth muscle

Maki, T., Kajioka, S., Itsumi, M., Kareman, E., Lee, K., Shiota, M. & Eto, M., Apr 2019, In : LUTS: Lower Urinary Tract Symptoms. 11, 2, p. O209-O217

Research output: Contribution to journalArticle

Smooth Muscle
Swine
Carbachol
Escin
Adrenergic Receptors
2018
3 Citations (Scopus)
Taxoids
Androgen Receptors
Prostatic Neoplasms
docetaxel
MDV 3100
3 Citations (Scopus)

Mineralocorticoid receptor signaling affects therapeutic effect of enzalutamide

Shiota, M., Fujimoto, N., Higashijima, K., Imada, K., Kashiwagi, E., Takeuchi, A., Inokuchi, J., Tatsugami, K., Kajioka, S., Uchiumi, T. & Eto, M., Oct 1 2018, In : Prostate. 78, 14, p. 1045-1052 8 p.

Research output: Contribution to journalArticle

Mineralocorticoid Receptors
Therapeutic Uses
Prostatic Neoplasms
Androgen Receptors
Adrenal Cortex Hormones
2 Citations (Scopus)

Overexpression of exchange protein directly activated by cAMP-1 (EPAC1) attenuates bladder cancer cell migration

Ichikawa, H., Itsumi, M., Kajioka, S., Maki, T., Lee, K., Tomita, M. & Yamaoka, S., Jan 1 2018, In : Biochemical and Biophysical Research Communications. 495, 1, p. 64-70 7 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Cell Movement
Cells
Proteins
Guanine Nucleotide Exchange Factors
1 Citation (Scopus)
Open Access
Mineralocorticoid Receptors
Genetic Polymorphisms
Androgens
Comorbidity
Hypertension
4 Citations (Scopus)

Role of K+ channels in regulating spontaneous activity in the muscularis mucosae of guinea pig bladder

Lee, K., Isogai, A., Antoh, M., Kajioka, S., Eto, M. & Hashitani, H., Jan 5 2018, In : European Journal of Pharmacology. 818, p. 30-37 8 p.

Research output: Contribution to journalArticle

Action Potentials
Guinea Pigs
Mucous Membrane
Urinary Bladder
Large-Conductance Calcium-Activated Potassium Channels
6 Citations (Scopus)
Gonadotropin-Releasing Hormone
Androgens
Testosterone
Prostatic Neoplasms
Serum
2017
12 Citations (Scopus)
Androgens
Prostatic Neoplasms
Oxidative Stress
Antioxidants
Alleles
1 Citation (Scopus)

Micro-Coordination of Pacemaker Potentials in the Intestine of the Mouse

Morishita, H., Iwata, N., Takai, C., Mochizuki, N., Kaji, N., Hori, M., Kajioka, S. & Nakayama, S., Jun 1 2017, In : Gastroenterology. 152, 8, p. 1831-1833.e4

Research output: Contribution to journalArticle

Intestines
2016
8 Citations (Scopus)

Actions of cAMP on calcium sensitization in human detrusor smooth muscle contraction

Hayashi, M., Kajioka, S., Itsumi, M., Takahashi, R., Shahab, N., Ishigami, T., Takeda, M., Masuda, N., Yamaguchi, A. & Naito, S., Jan 1 2016, In : BJU international. 117, 1, p. 179-191 13 p.

Research output: Contribution to journalArticle

Muscle Contraction
Smooth Muscle
rho-Associated Kinases
Carbachol
Cyclic AMP-Dependent Protein Kinases
12 Citations (Scopus)

Equol inhibits prostate cancer growth through degradation of androgen receptor by S-phase kinase-associated protein 2

Itsumi, M., Shiota, M., Takeuchi, A., Kashiwagi, E., Inokuchi, J., Tatsugami, K., Kajioka, S., Uchiumi, T., Naito, S., Eto, M. & Yokomizo, A., Jul 1 2016, In : Cancer Science. 107, 7, p. 1022-1028 7 p.

Research output: Contribution to journalArticle

S-Phase Kinase-Associated Proteins
Equol
Androgen Receptors
Isoflavones
Prostatic Neoplasms
7 Citations (Scopus)

Role of PTHrP and Sensory Nerve Peptides in Regulating Contractility of Muscularis Mucosae and Detrusor Smooth Muscle in the Guinea Pig Bladder

Lee, K., Mitsui, R., Kajioka, S., Naito, S. & Hashitani, H., Oct 1 2016, In : Journal of Urology. 196, 4, p. 1287-1294 8 p.

Research output: Contribution to journalArticle

Parathyroid Hormone-Related Protein
Smooth Muscle
Guinea Pigs
Mucous Membrane
Urinary Bladder
3 Citations (Scopus)

Surface vacuolar ATPase in ameloblastoma contributes to tumor invasion of the jaw bone

Yoshimoto, S., Morita, H., Matsubara, R., Mitsuyasu, T., Imai, Y., Kajioka, S., Yoneda, M., Ito, Y., Hirofuji, T., Nakamura, S. & Hirata, M., Mar 2016, In : International journal of oncology. 48, 3, p. 1258-1270 13 p.

Research output: Contribution to journalArticle

Vacuolar Proton-Translocating ATPases
Ameloblastoma
Jaw
RANK Ligand
Bone and Bones
2013
7 Citations (Scopus)

Involvement of IP3-receptor activation in endothelin-1-induced Ca2+ influx in rat pulmonary small artery

Kato, K., Okamura, K., Hatta, M., Morita, H., Kajioka, S., Naito, S. & Yamazaki, J., Nov 15 2013, In : European Journal of Pharmacology. 720, 1-3, p. 255-263 9 p.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate Receptors
Endothelin-1
Pulmonary Artery
Thapsigargin
Salts
3 Citations (Scopus)

Novel effect of 2-aminoethoxydiphenylborate through inhibition of calcium sensitization induced by Rho kinase activation in human detrusor smooth muscle

Shahab, N., Kajioka, S., Takahashi, R., Hayashi, M., Nakayama, S., Sakamoto, K., Takeda, M., Masuda, N. & Naito, S., May 15 2013, In : European Journal of Pharmacology. 708, 1-3, p. 14-20 7 p.

Research output: Contribution to journalArticle

rho-Associated Kinases
Smooth Muscle
Calcium
Carbachol
Protein Kinase C
3 Citations (Scopus)

Spatial Analysis of Slowly Oscillating Electric Activity in the Gut of Mice Using Low Impedance Arrayed Microelectrodes

Taniguchi, M., Kajioka, S., Shozib, H. B., Sawamura, K. & Nakayama, S., Oct 4 2013, In : PloS one. 8, 10, e75235.

Research output: Contribution to journalArticle

Spatial Analysis
Microelectrodes
impedance
Electric Impedance
digestive system
2012
13 Citations (Scopus)

Endogenous cardiac troponin T modulates Ca2+-mediated smooth muscle contraction

Kajioka, S., Takahashi-Yanaga, F., Shahab, N., Onimaru, M., Matsuda, M., Takahashi, R., Asano, H., Morita, H., Morimoto, S., Yonemitsu, Y., Hayashi, M., Seki, N., Sasaguri, T., Hirata, M., Nakayama, S. & Naito, S., Dec 1 2012, In : Scientific reports. 2, 979.

Research output: Contribution to journalArticle

Troponin T
Muscle Contraction
Smooth Muscle
Actin Cytoskeleton
Tropomyosin
7 Citations (Scopus)
rho-Associated Kinases
Carbachol
Muscarinic Receptors
Protein Kinase C
Smooth Muscle
9 Citations (Scopus)
Urinary Bladder Neck Obstruction
rho-Associated Kinases
Carbachol
Protein Kinase C
Smooth Muscle
2011
3 Citations (Scopus)

Diphosphate regulation of adenosine triphosphate sensitive potassium channel in human bladder smooth muscle cells

Kajioka, S., Shahab, N., Asano, H., Morita, H., Sugihara, M., Takahashi-Yanaga, F., Yoshihara, T., Nakayama, S., Seki, N. & Naito, S., Aug 1 2011, In : Journal of Urology. 186, 2, p. 736-744 9 p.

Research output: Contribution to journalArticle

Diphosphates
Potassium Channels
Smooth Muscle Myocytes
Urinary Bladder
Adenosine Triphosphate
4 Citations (Scopus)

Dual signaling pathways of arterial constriction by extracellular uridine 5′-triphosphate in the rat

Sugihara, M., Morita, H., Matsuda, M., Umebayashi, H., Kajioka, S., Ito, S., Nishida, M., Inoue, R., Futatsuki, T., Yamazaki, J., Mori, Y., Inoue, R., Ito, Y., Abe, K. & Hirata, M., Mar 24 2011, In : Journal of Pharmacological Sciences. 115, 3, p. 293-308 16 p.

Research output: Contribution to journalArticle

Uridine Triphosphate
Constriction
Purinergic P2X1 Receptors
Adenosine Triphosphate
Muscle Cells
2010
1 Citation (Scopus)

[Etiology of overactive bladder and its therapeutic perspective--focusing on a myogenic basis for the overactive bladder].

Kajioka, S., Seki, N., Shahab, N., Yunoki, T. & Naito, S., May 1 2010, In : Fukuoka igaku zasshi = Hukuoka acta medica. 101, 5, p. 94-100 7 p.

Research output: Contribution to journalReview article

Interstitial Cells of Cajal
Overactive Urinary Bladder
Therapeutics
2009
7 Citations (Scopus)

The profiles and patterns of detrusor overactivity and their association with overactive bladder symptoms in men with benign prostatic enlargement associated with detrusor overactivity

Shahab, N., Seki, N., Takahashi, R., Kajioka, S., Takei, M., Yamaguchi, A. & Naito, S., Nov 1 2009, In : Neurourology and Urodynamics. 28, 8, p. 953-958 6 p.

Research output: Contribution to journalArticle

Nocturia
Overactive Urinary Bladder
Urinary Bladder
Transurethral Resection of Prostate
Urodynamics
2008
11 Citations (Scopus)
Sulfonylurea Receptors
Cromakalim
KATP Channels
Smooth Muscle Myocytes
Signal Transduction

Mechanisms of resistance to penicillins in Enterococcus faecalis

Hiraga, N., Muratani, T., Shiozaki, K., Lee, S., Ono, S., Matsumoto, T., Kajioka, S., Naito, S., Kobayashi, T. & Saku, H., Feb 1 2008, In : Nishinihon Journal of Urology. 70, 2, p. 41-46 6 p.

Research output: Contribution to journalArticle

Penicillin Resistance
Enterococcus faecalis
Penicillins
Penicillin-Binding Proteins
beta-Lactamases
8 Citations (Scopus)

Oscillatory membrane currents paradoxically induced via NO-activated pathways in detrusor cells

Kajioka, S., Nakayama, S., Seki, N., Naito, S. & Brading, A. F., Aug 2008, In : Cell Calcium. 44, 2, p. 202-209 8 p.

Research output: Contribution to journalArticle

Nitroprusside
Nitric Oxide
Membranes
Urinary Bladder
Niflumic Acid
2007
19 Citations (Scopus)

Calcium-associated mechanisms in gut pacemaker activity: Interstitial Cajal-like Cells Review Series

Nakayama, S., Kajioka, S., Goto, K., Takaki, M. & Liu, H. N., Sep 1 2007, In : Journal of Cellular and Molecular Medicine. 11, 5, p. 958-968 11 p.

Research output: Contribution to journalArticle

Interstitial Cells of Cajal
Pacemakers
Calcium
Ion Channels
Cations
2006
12 Citations (Scopus)

Tyrosine kinase inhibitors and ATP modulate the conversion of smooth muscle L-type Ca2+ channels toward a second open state

Nakayama, S., Ito, Y., Sato, S., Kamijo, A., Liu, H. N. & Kajioka, S., Jul 2006, In : FASEB Journal. 20, 9

Research output: Contribution to journalArticle

smooth muscle
Protein-Tyrosine Kinases
Smooth Muscle
tyrosine
Muscle
2005
20 Citations (Scopus)

Involvement of ryanodine receptors in muscarinic receptor-mediated membrane current oscillation in urinary bladder smooth muscle

Kajioka, S., Nakayama, S., Asano, H. & Brading, A. F., Jan 1 2005, In : American Journal of Physiology - Cell Physiology. 288, 1 57-1, p. C100-C108

Research output: Contribution to journalArticle

Ryanodine Receptor Calcium Release Channel
Muscarinic Receptors
Smooth Muscle
Urinary Bladder
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole
18 Citations (Scopus)

Sulphonylurea receptors differently modulate ICC pacemaker Ca2+ activity and smooth muscle contractility

Nakayama, S., Ohya, S., Liu, H. N., Watanabe, T., Furuzono, S., Wang, J., Nishizawa, Y., Aoyama, M., Murase, N., Matsubara, T., Ito, Y., Imaizumi, Y. & Kajioka, S., Sep 15 2005, In : Journal of Cell Science. 118, 18, p. 4163-4173 11 p.

Research output: Contribution to journalArticle

Sulfonylurea Receptors
Cromakalim
Smooth Muscle
Gastrointestinal Motility
Sulfonylurea Compounds
2004
35 Citations (Scopus)

Investigation of the effect of the c-kit inhibitor Glivec on isolated guinea-pig detrusor preparations

Kubota, Y., Kajioka, S., Biers, S. M., Yokota, E., Kohri, K. & Brading, A. F., Sep 30 2004, In : Autonomic Neuroscience: Basic and Clinical. 115, 1-2, p. 64-73 10 p.

Research output: Contribution to journalArticle

Guinea Pigs
Action Potentials
Urinary Bladder
Proto-Oncogene Proteins c-kit
Overactive Urinary Bladder
12 Citations (Scopus)

Inward current oscillation underlying tonic contraction caused via ET A receptors in pig detrusor smooth muscle

Kajioka, S., Nakayama, S., McCoy, R., McMurray, G., Abe, K. & Brading, A. F., Jan 1 2004, In : American Journal of Physiology - Renal Physiology. 286, 1 55-1, p. F77-F85

Research output: Contribution to journalArticle

Endothelin-1
Smooth Muscle
Swine
Urinary Bladder
Endothelin-2
2002
35 Citations (Scopus)

Ca2+ channel properties in smooth muscle cells of the urinary bladder from pig and human

Kajioka, S., Nakayama, S., McMurray, G., Abe, K. & Brading, A. F., May 17 2002, In : European Journal of Pharmacology. 443, 1-3, p. 19-29 11 p.

Research output: Contribution to journalArticle

Smooth Muscle Myocytes
Urinary Bladder
Swine
Carbachol
Muscarinic Agonists
1999
8 Citations (Scopus)

Effects of phosphorylation-related drugs on slow Ca2+ tail current in guinea-pig detrusor cells

Smith, L. M., Kajioka, S. I., Brading, A. F. & Nakayama, S., Apr 9 1999, In : European Journal of Pharmacology. 370, 2, p. 187-193 7 p.

Research output: Contribution to journalArticle

Tail
Guinea Pigs
Phosphorylation
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
Pharmaceutical Preparations
1993
11 Citations (Scopus)

A target K+ channel for the LP-805-induced hyperpolarization in smooth muscle cells of the rabbit portal vein

Kamouchi, M., Kajioka, S., Sakai, T., Kitamura, K. & Kuriyama, H., Mar 1993, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 347, 3, p. 329-335 7 p.

Research output: Contribution to journalArticle

Portal Vein
Smooth Muscle Myocytes
Rabbits
Large-Conductance Calcium-Activated Potassium Channels
Charybdotoxin
1992

Potassium channel openers open the different K channels in the smooth muscle cells of rat and rabbit portal veins

Kitamura, K., Kajioka, S. & Kuriyama, H., Jul 16 1992, In : Therapeutic Research. 13, 5, p. 61-68 8 p.

Research output: Contribution to journalArticle

Potassium Channels
Portal Vein
Smooth Muscle Myocytes
Rabbits

Properties of ATP-sensitive K+ channel in the smooth muscle cells of the rabbit portal vein

Kajioka, S., Kitamura, K. & Kuriyama, H., Aug 14 1992, In : Japanese Journal of Pharmacology. 58, SUPPL. 2, p. 343P

Research output: Contribution to journalArticle

Potassium Channels
Portal Vein
Vascular Smooth Muscle
Smooth Muscle Myocytes
Adenosine Triphosphate
1991
3 Citations (Scopus)

Characteristics of the voltage-dependent calcium channel in smooth muscle: Patch-clamp studies

Kitamura, K., Teramoto, N., Oike, M., Xiong, Z., Kajioka, S., Inoue, Y., Nilius, B. & Kuriyama, H., Dec 1 1991, In : Advances in experimental medicine and biology. 304, p. 209-227 19 p.

Research output: Contribution to journalArticle

Electrophysiology
Calcium Channels
Smooth Muscle
128 Citations (Scopus)

Guanosine diphosphate activates an adenosine 5'‐triphosphate‐sensitive K+ channel in the rabbit portal vein.

Kajioka, S., Kitamura, K. & Kuriyama, H., Dec 1 1991, In : The Journal of Physiology. 444, 1, p. 397-418 22 p.

Research output: Contribution to journalArticle

Pinacidil
Guanosine
Portal Vein
Adenosine Diphosphate
Rabbits
7 Citations (Scopus)
Bradycardia
Portal Vein
Smooth Muscle Myocytes
Rabbits
Glyburide
29 Citations (Scopus)

Mechanisms of vasodilatation induced by potassium-channel activators

Kajioka, S., Nakashima, M., Kitamura, K. & Kuriyama, H., Jan 1 1991, In : Clinical Science. 81, 2, p. 129-139 11 p.

Research output: Contribution to journalReview article

Tetraethylammonium Compounds
Tetraethylammonium
Glyburide
Potassium Channels
Vascular Smooth Muscle
21 Citations (Scopus)

Pinacidil inhibits the ryanodine‐sensitive outward current and glibenclamide antagonizes its action in cells from the rabbit portal vein

Xiong, Z., Kajioka, S., Sakai, T., Kitamura, K. & Kuriyama, H., Apr 1991, In : British Journal of Pharmacology. 102, 4, p. 788-790 3 p.

Research output: Contribution to journalArticle

Pinacidil
Glyburide
Portal Vein
Rabbits
Vasodilator Agents
1990
62 Citations (Scopus)

Actions of cromakalim on ionic currents recorded from single smooth muscle cells of the rat portal vein

Okabe, K., Kajioka, S., Nakao, K., Kitamura, K., Kuriyama, H. & Weston, A. H., Mar 30 1990, In : Journal of Pharmacology and Experimental Therapeutics. 252, 2, p. 832-839 8 p.

Research output: Contribution to journalArticle

Cromakalim
Portal Vein
Smooth Muscle Myocytes
Egtazic Acid
Salts
1 Citation (Scopus)

Features of the potassium channel in vascular smooth muscle cells and their modulating drugs

Kuriyama, H., Kajioka, S. & Kitamura, K., Jul 1 1990, In : European Journal of Pharmacology. 183, 1, 1 p.

Research output: Contribution to journalArticle

Potassium Channels
Vascular Smooth Muscle
Smooth Muscle Myocytes
Pharmaceutical Preparations
72 Citations (Scopus)
Nicorandil
Calcium-Activated Potassium Channels
Portal Vein
Smooth Muscle Myocytes
4-Aminopyridine