Shunichi Kajioka

2019

Cigarette smoking augments androgen receptor activity and promotes resistance to antiandrogen therapy

Shiota, M., Ushijima, M., Imada, K., Kashiwagi, E., Takeuchi, A., Inokuchi, J., Tatsugami, K., Kajioka, S. & Eto, M., Jul 1 2019, In : Prostate. 79, 10, p. 1147-1155 9 p.

Research output: Contribution to journal › Article

Androgen Antagonists

Androgen Receptors

docetaxel

Prostatic Neoplasms

Smoking

1 Citation (Scopus)

Contractile elements and their sympathetic regulations in the pig urinary bladder: a species and regional comparative study

Mitsui, R., Lee, K., Uchiyama, A., Hayakawa, S., Kinoshita, F., Kajioka, S., Eto, M. & Hashitani, H., Jan 1 2019, (Accepted/In press) In : Cell and tissue research.

Research output: Contribution to journal › Article

Mucous Membrane

Urinary Bladder

Swine

Smooth Muscle

Tyrosine 3-Monooxygenase

Extracellular calcium stimulates osteogenic differentiation of human adipose-derived stem cells by enhancing bone morphogenetic protein-2 expression

Yanai, R., Tetsuo, F., Ito, S., Itsumi, M., Yoshizumi, J., Maki, T., Mori, Y., Kubota, Y. & Kajioka, S., Nov 2019, In : Cell Calcium. 83, 102058.

Research output: Contribution to journal › Article

Bone Morphogenetic Protein 2

Stem Cells

Calcium

Calcium-Sensing Receptors

Messenger RNA

Fetal Membrane Inflammation Induces Preterm Birth Via Toll-Like Receptor 2 in Mice With Chronic Gingivitis

Konishi, H., Urabe, S., Miyoshi, H., Teraoka, Y., Maki, T., Furusho, H., Miyauchi, M., Takata, T., Kudo, Y. & Kajioka, S., Jul 1 2019, In : Reproductive Sciences. 26, 7, p. 869-878 10 p.

Research output: Contribution to journal › Article

Extraembryonic Membranes

Gingivitis

Premature Birth

Toll-Like Receptor 2

Inflammation

1 Citation (Scopus)

Influence of genetic polymorphisms and habitual caffeine intake on the changes in blood pressure, pulse rate, and calculation speed after caffeine intake: A prospective, double blind, randomized trial in healthy volunteers

Yoshihara, T., Zaitsu, M., Shiraishi, F., Arima, H., Takahashi-Yanaga, F., Arioka, M., Kajioka, S. & Sasaguri, T., Mar 2019, In : Journal of Pharmacological Sciences. 139, 3, p. 209-214 6 p.

Research output: Contribution to journal › Article

Open Access

Genetic Polymorphisms

Caffeine

Healthy Volunteers

Heart Rate

Blood Pressure

2 Citations (Scopus)

Mirabegron induces relaxant effects via cAMP signaling-dependent and -independent pathways in detrusor smooth muscle

Maki, T., Kajioka, S., Itsumi, M., Kareman, E., Lee, K., Shiota, M. & Eto, M., Apr 2019, In : LUTS: Lower Urinary Tract Symptoms. 11, 2, p. O209-O217

Research output: Contribution to journal › Article

Smooth Muscle

Swine

Carbachol

Escin

Adrenergic Receptors

2018

3 Citations (Scopus)

Collateral resistance to taxanes in enzalutamide-resistant prostate cancer through aberrant androgen receptor and its variants

Shiota, M., Dejima, T., Yamamoto, Y., Takeuchi, A., Imada, K., Kashiwagi, E., Inokuchi, J., Tatsugami, K., Kajioka, S., Uchiumi, T. & Eto, M., Oct 2018, In : Cancer Science. 109, 10, p. 3224-3234 11 p.

Research output: Contribution to journal › Article

Taxoids

Androgen Receptors

Prostatic Neoplasms

docetaxel

MDV 3100

3 Citations (Scopus)

Mineralocorticoid receptor signaling affects therapeutic effect of enzalutamide

Shiota, M., Fujimoto, N., Higashijima, K., Imada, K., Kashiwagi, E., Takeuchi, A., Inokuchi, J., Tatsugami, K., Kajioka, S., Uchiumi, T. & Eto, M., Oct 1 2018, In : Prostate. 78, 14, p. 1045-1052 8 p.

Research output: Contribution to journal › Article

Mineralocorticoid Receptors

Therapeutic Uses

Prostatic Neoplasms

Androgen Receptors

Adrenal Cortex Hormones

2 Citations (Scopus)

Overexpression of exchange protein directly activated by cAMP-1 (EPAC1) attenuates bladder cancer cell migration

Ichikawa, H., Itsumi, M., Kajioka, S., Maki, T., Lee, K., Tomita, M. & Yamaoka, S., Jan 1 2018, In : Biochemical and Biophysical Research Communications. 495, 1, p. 64-70 7 p.

Research output: Contribution to journal › Article

Urinary Bladder Neoplasms

Cell Movement

Cells

Proteins

Guanine Nucleotide Exchange Factors

1 Citation (Scopus)

Prognostic impact of genetic polymorphism in mineralocorticoid receptor and comorbidity with hypertension in androgen-deprivation therapy

Shiota, M., Fujimoto, N., Imada, K., Kashiwagi, E., Takeuchi, A., Inokuchi, J., Tatsugami, K., Kajioka, S., Uchiumi, T. & Eto, M., Jan 1 2018, In : Frontiers in Oncology. 8, DEC, 635.

Research output: Contribution to journal › Article

Open Access

Mineralocorticoid Receptors

Genetic Polymorphisms

Androgens

Comorbidity

Hypertension

4 Citations (Scopus)

Role of K⁺ channels in regulating spontaneous activity in the muscularis mucosae of guinea pig bladder

Lee, K., Isogai, A., Antoh, M., Kajioka, S., Eto, M. & Hashitani, H., Jan 5 2018, In : European Journal of Pharmacology. 818, p. 30-37 8 p.

Research output: Contribution to journal › Article

Action Potentials

Guinea Pigs

Mucous Membrane

Urinary Bladder

Large-Conductance Calcium-Activated Potassium Channels

6 Citations (Scopus)

The Association of Polymorphisms in the Gene Encoding Gonadotropin-Releasing Hormone with Serum Testosterone Level during Androgen Deprivation Therapy and Prognosis of Metastatic Prostate Cancer

Shiota, M., Fujimoto, N., Takeuchi, A., Kashiwagi, E., Dejima, T., Inokuchi, J., Tatsugami, K., Yokomizo, A., Kajioka, S., Uchiumi, T. & Eto, M., Mar 2018, In : Journal of Urology. 199, 3, p. 734-740 7 p.

Research output: Contribution to journal › Article

Gonadotropin-Releasing Hormone

Androgens

Testosterone

Prostatic Neoplasms

Serum

2017

12 Citations (Scopus)

Gene polymorphisms in antioxidant enzymes correlate with the efficacy of androgen-deprivation therapy for prostate cancer with implications of oxidative stress

Shiota, M., Fujimoto, N., Itsumi, M., Takeuchi, A., Inokuchi, J., Tatsugami, K., Yokomizo, A., Kajioka, S., Uchiumi, T. & Eto, M., Jan 1 2017, In : Annals of Oncology. 28, 3, p. 569-575 7 p.

Research output: Contribution to journal › Article

Androgens

Prostatic Neoplasms

Oxidative Stress

Antioxidants

Alleles

1 Citation (Scopus)

Micro-Coordination of Pacemaker Potentials in the Intestine of the Mouse

Morishita, H., Iwata, N., Takai, C., Mochizuki, N., Kaji, N., Hori, M., Kajioka, S. & Nakayama, S., Jun 1 2017, In : Gastroenterology. 152, 8, p. 1831-1833.e4

Research output: Contribution to journal › Article

Intestines

2016

8 Citations (Scopus)

Actions of cAMP on calcium sensitization in human detrusor smooth muscle contraction

Hayashi, M., Kajioka, S., Itsumi, M., Takahashi, R., Shahab, N., Ishigami, T., Takeda, M., Masuda, N., Yamaguchi, A. & Naito, S., Jan 1 2016, In : BJU international. 117, 1, p. 179-191 13 p.

Research output: Contribution to journal › Article

Muscle Contraction

Smooth Muscle

rho-Associated Kinases

Carbachol

Cyclic AMP-Dependent Protein Kinases

12 Citations (Scopus)

Equol inhibits prostate cancer growth through degradation of androgen receptor by S-phase kinase-associated protein 2

Itsumi, M., Shiota, M., Takeuchi, A., Kashiwagi, E., Inokuchi, J., Tatsugami, K., Kajioka, S., Uchiumi, T., Naito, S., Eto, M. & Yokomizo, A., Jul 1 2016, In : Cancer Science. 107, 7, p. 1022-1028 7 p.

Research output: Contribution to journal › Article

S-Phase Kinase-Associated Proteins

Equol

Androgen Receptors

Isoflavones

Prostatic Neoplasms

7 Citations (Scopus)

Role of PTHrP and Sensory Nerve Peptides in Regulating Contractility of Muscularis Mucosae and Detrusor Smooth Muscle in the Guinea Pig Bladder

Lee, K., Mitsui, R., Kajioka, S., Naito, S. & Hashitani, H., Oct 1 2016, In : Journal of Urology. 196, 4, p. 1287-1294 8 p.

Research output: Contribution to journal › Article

Parathyroid Hormone-Related Protein

Smooth Muscle

Guinea Pigs

Mucous Membrane

Urinary Bladder

3 Citations (Scopus)

Surface vacuolar ATPase in ameloblastoma contributes to tumor invasion of the jaw bone

Yoshimoto, S., Morita, H., Matsubara, R., Mitsuyasu, T., Imai, Y., Kajioka, S., Yoneda, M., Ito, Y., Hirofuji, T., Nakamura, S. & Hirata, M., Mar 2016, In : International journal of oncology. 48, 3, p. 1258-1270 13 p.

Research output: Contribution to journal › Article

Vacuolar Proton-Translocating ATPases

Ameloblastoma

Jaw

RANK Ligand

Bone and Bones

2013

7 Citations (Scopus)

Involvement of IP₃-receptor activation in endothelin-1-induced Ca²⁺ influx in rat pulmonary small artery

Kato, K., Okamura, K., Hatta, M., Morita, H., Kajioka, S., Naito, S. & Yamazaki, J., Nov 15 2013, In : European Journal of Pharmacology. 720, 1-3, p. 255-263 9 p.

Research output: Contribution to journal › Article

Inositol 1,4,5-Trisphosphate Receptors

Endothelin-1

Pulmonary Artery

Thapsigargin

Salts

3 Citations (Scopus)

Novel effect of 2-aminoethoxydiphenylborate through inhibition of calcium sensitization induced by Rho kinase activation in human detrusor smooth muscle

Shahab, N., Kajioka, S., Takahashi, R., Hayashi, M., Nakayama, S., Sakamoto, K., Takeda, M., Masuda, N. & Naito, S., May 15 2013, In : European Journal of Pharmacology. 708, 1-3, p. 14-20 7 p.

Research output: Contribution to journal › Article

rho-Associated Kinases

Smooth Muscle

Calcium

Carbachol

Protein Kinase C

3 Citations (Scopus)

Spatial Analysis of Slowly Oscillating Electric Activity in the Gut of Mice Using Low Impedance Arrayed Microelectrodes

Taniguchi, M., Kajioka, S., Shozib, H. B., Sawamura, K. & Nakayama, S., Oct 4 2013, In : PloS one. 8, 10, e75235.

Research output: Contribution to journal › Article

Spatial Analysis

Microelectrodes

impedance

Electric Impedance

digestive system

2012

13 Citations (Scopus)

Endogenous cardiac troponin T modulates Ca²⁺-mediated smooth muscle contraction

Kajioka, S., Takahashi-Yanaga, F., Shahab, N., Onimaru, M., Matsuda, M., Takahashi, R., Asano, H., Morita, H., Morimoto, S., Yonemitsu, Y., Hayashi, M., Seki, N., Sasaguri, T., Hirata, M., Nakayama, S. & Naito, S., Dec 1 2012, In : Scientific reports. 2, 979.

Research output: Contribution to journal › Article

Troponin T

Muscle Contraction

Smooth Muscle

Actin Cytoskeleton

Tropomyosin

7 Citations (Scopus)

Functional role of muscarinic receptor subtypes in calcium sensitization and their contribution to rho-kinase and protein kinase C pathways in contraction of human detrusor smooth muscle

Shahab, N., Kajioka, S., Seki, N. & Naito, S., May 2012, In : Urology. 79, 5, p. 1184.e7-1184.e13

Research output: Contribution to journal › Article

rho-Associated Kinases

Carbachol

Muscarinic Receptors

Protein Kinase C

Smooth Muscle

9 Citations (Scopus)

Obstruction enhances rho-kinase pathway and diminishes protein kinase C pathway in carbachol-induced calcium sensitization in contraction of α-toxin permeabilized guinea pig detrusor smooth muscle

Shahab, N., Kajioka, S., Takahashi-Yanaga, F., Onimaru, M., Matsuda, M., Seki, N. & Naito, S., Apr 1 2012, In : Neurourology and Urodynamics. 31, 4, p. 593-599 7 p.

Research output: Contribution to journal › Article

Urinary Bladder Neck Obstruction

rho-Associated Kinases

Carbachol

Protein Kinase C

Smooth Muscle

2011

3 Citations (Scopus)

Diphosphate regulation of adenosine triphosphate sensitive potassium channel in human bladder smooth muscle cells

Kajioka, S., Shahab, N., Asano, H., Morita, H., Sugihara, M., Takahashi-Yanaga, F., Yoshihara, T., Nakayama, S., Seki, N. & Naito, S., Aug 1 2011, In : Journal of Urology. 186, 2, p. 736-744 9 p.

Research output: Contribution to journal › Article

Diphosphates

Potassium Channels

Smooth Muscle Myocytes

Urinary Bladder

Adenosine Triphosphate

4 Citations (Scopus)

Dual signaling pathways of arterial constriction by extracellular uridine 5′-triphosphate in the rat

Sugihara, M., Morita, H., Matsuda, M., Umebayashi, H., Kajioka, S., Ito, S., Nishida, M., Inoue, R., Futatsuki, T., Yamazaki, J., Mori, Y., Inoue, R., Ito, Y., Abe, K. & Hirata, M., Mar 24 2011, In : Journal of Pharmacological Sciences. 115, 3, p. 293-308 16 p.

Research output: Contribution to journal › Article

Uridine Triphosphate

Constriction

Purinergic P2X1 Receptors

Adenosine Triphosphate

Muscle Cells

2009

7 Citations (Scopus)

The profiles and patterns of detrusor overactivity and their association with overactive bladder symptoms in men with benign prostatic enlargement associated with detrusor overactivity

Shahab, N., Seki, N., Takahashi, R., Kajioka, S., Takei, M., Yamaguchi, A. & Naito, S., Nov 1 2009, In : Neurourology and Urodynamics. 28, 8, p. 953-958 6 p.

Research output: Contribution to journal › Article

Nocturia

Overactive Urinary Bladder

Urinary Bladder

Transurethral Resection of Prostate

Urodynamics

2008

11 Citations (Scopus)

Levcromakalim and MgGDP activate small conductance ATP-sensitive K ⁺ channels of K⁺ channel pore 6.1/sulfonylurea receptor 2A in pig detrusor smooth muscle cells: Uncoupling of cAMP signal pathways

Kajioka, S., Nakayama, S., Asano, H., Seki, N., Naito, S. & Brading, A. F., Oct 1 2008, In : Journal of Pharmacology and Experimental Therapeutics. 327, 1, p. 114-123 10 p.

Research output: Contribution to journal › Article

Sulfonylurea Receptors

Cromakalim

KATP Channels

Smooth Muscle Myocytes

Signal Transduction

Mechanisms of resistance to penicillins in Enterococcus faecalis

Hiraga, N., Muratani, T., Shiozaki, K., Lee, S., Ono, S., Matsumoto, T., Kajioka, S., Naito, S., Kobayashi, T. & Saku, H., Feb 1 2008, In : Nishinihon Journal of Urology. 70, 2, p. 41-46 6 p.

Research output: Contribution to journal › Article

Penicillin Resistance

Enterococcus faecalis

Penicillins

Penicillin-Binding Proteins

beta-Lactamases

8 Citations (Scopus)

Oscillatory membrane currents paradoxically induced via NO-activated pathways in detrusor cells

Kajioka, S., Nakayama, S., Seki, N., Naito, S. & Brading, A. F., Aug 2008, In : Cell Calcium. 44, 2, p. 202-209 8 p.

Research output: Contribution to journal › Article

Nitroprusside

Nitric Oxide

Membranes

Urinary Bladder

Niflumic Acid

2007

19 Citations (Scopus)

Calcium-associated mechanisms in gut pacemaker activity: Interstitial Cajal-like Cells Review Series

Nakayama, S., Kajioka, S., Goto, K., Takaki, M. & Liu, H. N., Sep 1 2007, In : Journal of Cellular and Molecular Medicine. 11, 5, p. 958-968 11 p.

Research output: Contribution to journal › Article

Interstitial Cells of Cajal

Pacemakers

Calcium

Ion Channels

Cations

2006

12 Citations (Scopus)

Tyrosine kinase inhibitors and ATP modulate the conversion of smooth muscle L-type Ca2+ channels toward a second open state

Nakayama, S., Ito, Y., Sato, S., Kamijo, A., Liu, H. N. & Kajioka, S., Jul 2006, In : FASEB Journal. 20, 9

Research output: Contribution to journal › Article

smooth muscle

Protein-Tyrosine Kinases

Smooth Muscle

tyrosine

Muscle

2005

20 Citations (Scopus)

Involvement of ryanodine receptors in muscarinic receptor-mediated membrane current oscillation in urinary bladder smooth muscle

Kajioka, S., Nakayama, S., Asano, H. & Brading, A. F., Jan 1 2005, In : American Journal of Physiology - Cell Physiology. 288, 1 57-1, p. C100-C108

Research output: Contribution to journal › Article

Ryanodine Receptor Calcium Release Channel

Muscarinic Receptors

Smooth Muscle

Urinary Bladder

1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole

18 Citations (Scopus)

Sulphonylurea receptors differently modulate ICC pacemaker Ca²⁺ activity and smooth muscle contractility

Nakayama, S., Ohya, S., Liu, H. N., Watanabe, T., Furuzono, S., Wang, J., Nishizawa, Y., Aoyama, M., Murase, N., Matsubara, T., Ito, Y., Imaizumi, Y. & Kajioka, S., Sep 15 2005, In : Journal of Cell Science. 118, 18, p. 4163-4173 11 p.

Research output: Contribution to journal › Article

Sulfonylurea Receptors

Cromakalim

Smooth Muscle

Gastrointestinal Motility

Sulfonylurea Compounds

2004

35 Citations (Scopus)

Investigation of the effect of the c-kit inhibitor Glivec on isolated guinea-pig detrusor preparations

Kubota, Y., Kajioka, S., Biers, S. M., Yokota, E., Kohri, K. & Brading, A. F., Sep 30 2004, In : Autonomic Neuroscience: Basic and Clinical. 115, 1-2, p. 64-73 10 p.

Research output: Contribution to journal › Article

Guinea Pigs

Action Potentials

Urinary Bladder

Proto-Oncogene Proteins c-kit

Overactive Urinary Bladder

12 Citations (Scopus)

Inward current oscillation underlying tonic contraction caused via ET _A receptors in pig detrusor smooth muscle

Kajioka, S., Nakayama, S., McCoy, R., McMurray, G., Abe, K. & Brading, A. F., Jan 1 2004, In : American Journal of Physiology - Renal Physiology. 286, 1 55-1, p. F77-F85

Research output: Contribution to journal › Article

Endothelin-1

Smooth Muscle

Swine

Urinary Bladder

Endothelin-2

2002

35 Citations (Scopus)

Ca2+ channel properties in smooth muscle cells of the urinary bladder from pig and human

Kajioka, S., Nakayama, S., McMurray, G., Abe, K. & Brading, A. F., May 17 2002, In : European Journal of Pharmacology. 443, 1-3, p. 19-29 11 p.

Research output: Contribution to journal › Article

Smooth Muscle Myocytes

Urinary Bladder

Swine

Carbachol

Muscarinic Agonists

1999

8 Citations (Scopus)

Effects of phosphorylation-related drugs on slow Ca²⁺ tail current in guinea-pig detrusor cells

Smith, L. M., Kajioka, S. I., Brading, A. F. & Nakayama, S., Apr 9 1999, In : European Journal of Pharmacology. 370, 2, p. 187-193 7 p.

Research output: Contribution to journal › Article

Tail

Guinea Pigs

Phosphorylation

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine

Pharmaceutical Preparations

1993

11 Citations (Scopus)

A target K⁺ channel for the LP-805-induced hyperpolarization in smooth muscle cells of the rabbit portal vein

Kamouchi, M., Kajioka, S., Sakai, T., Kitamura, K. & Kuriyama, H., Mar 1993, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 347, 3, p. 329-335 7 p.

Research output: Contribution to journal › Article

Portal Vein

Smooth Muscle Myocytes

Rabbits

Large-Conductance Calcium-Activated Potassium Channels

Charybdotoxin

1992

Potassium channel openers open the different K channels in the smooth muscle cells of rat and rabbit portal veins

Kitamura, K., Kajioka, S. & Kuriyama, H., Jul 16 1992, In : Therapeutic Research. 13, 5, p. 61-68 8 p.

Research output: Contribution to journal › Article

Potassium Channels

Portal Vein

Smooth Muscle Myocytes

Rabbits

Properties of ATP-sensitive K⁺ channel in the smooth muscle cells of the rabbit portal vein

Kajioka, S., Kitamura, K. & Kuriyama, H., Aug 14 1992, In : Japanese Journal of Pharmacology. 58, SUPPL. 2, p. 343P

Research output: Contribution to journal › Article

Potassium Channels

Portal Vein

Vascular Smooth Muscle

Smooth Muscle Myocytes

Adenosine Triphosphate

1991

3 Citations (Scopus)

Characteristics of the voltage-dependent calcium channel in smooth muscle: Patch-clamp studies

Kitamura, K., Teramoto, N., Oike, M., Xiong, Z., Kajioka, S., Inoue, Y., Nilius, B. & Kuriyama, H., Dec 1 1991, In : Advances in experimental medicine and biology. 304, p. 209-227 19 p.

Research output: Contribution to journal › Article

Electrophysiology

Calcium Channels

Smooth Muscle

128 Citations (Scopus)

Guanosine diphosphate activates an adenosine 5'‐triphosphate‐sensitive K+ channel in the rabbit portal vein.

Kajioka, S., Kitamura, K. & Kuriyama, H., Dec 1 1991, In : The Journal of Physiology. 444, 1, p. 397-418 22 p.

Research output: Contribution to journal › Article

Pinacidil

Guanosine

Portal Vein

Adenosine Diphosphate

Rabbits

7 Citations (Scopus)

Ionic currents involved in vasodilating actions of E4080, a newly synthesized bradycardia-inducing agent, in dispersed smooth muscle cells of the rabbit portal vein

Kamouchi, M., Xiong, Z., Teramoto, N., Kajioka, S., Okabe, K. & Kitamura, K., Dec 1 1991, In : Journal of Pharmacology and Experimental Therapeutics. 259, 3, p. 1396-1403 8 p.

Research output: Contribution to journal › Article

Bradycardia

Portal Vein

Smooth Muscle Myocytes

Rabbits

Glyburide

21 Citations (Scopus)

Pinacidil inhibits the ryanodine‐sensitive outward current and glibenclamide antagonizes its action in cells from the rabbit portal vein

Xiong, Z., Kajioka, S., Sakai, T., Kitamura, K. & Kuriyama, H., Apr 1991, In : British Journal of Pharmacology. 102, 4, p. 788-790 3 p.

Research output: Contribution to journal › Article

Pinacidil

Glyburide

Portal Vein

Rabbits

Vasodilator Agents

1990

62 Citations (Scopus)

Actions of cromakalim on ionic currents recorded from single smooth muscle cells of the rat portal vein

Okabe, K., Kajioka, S., Nakao, K., Kitamura, K., Kuriyama, H. & Weston, A. H., Mar 30 1990, In : Journal of Pharmacology and Experimental Therapeutics. 252, 2, p. 832-839 8 p.

Research output: Contribution to journal › Article

Cromakalim

Portal Vein

Smooth Muscle Myocytes

Egtazic Acid

Salts

1 Citation (Scopus)

Features of the potassium channel in vascular smooth muscle cells and their modulating drugs

Kuriyama, H., Kajioka, S. & Kitamura, K., Jul 1 1990, In : European Journal of Pharmacology. 183, 1, 1 p.

Research output: Contribution to journal › Article

Potassium Channels

Vascular Smooth Muscle

Smooth Muscle Myocytes

Pharmaceutical Preparations

72 Citations (Scopus)

Nicorandil opens a calcium-dependent potassium channel in smooth muscle cells of the rat portal vein

Kajioka, S., Oike, M. & Kitamura, K., Oct 17 1990, In : Journal of Pharmacology and Experimental Therapeutics. 254, 3, p. 905-913 9 p.

Research output: Contribution to journal › Article

Nicorandil

Calcium-Activated Potassium Channels

Portal Vein

Smooth Muscle Myocytes

4-Aminopyridine

5 Citations (Scopus)

Pinacidil opens the ATP-sensitive and Ca-dependent K channel in smooth muscle cells of the rat and rabbit portal veins

Kajioka, S., Sakai, T., Kitamura, K. & Kuriyama, H., Jan 1 1990, In : European Journal of Pharmacology. 183, 2, p. 268-269 2 p.

Research output: Contribution to journal › Article

Pinacidil

Portal Vein

Smooth Muscle Myocytes

Adenosine Triphosphate

Rabbits

1989

Variety of Ca2+ channel in plasma membrane

Kajioka, S., Katsuyama, H. & Kuriyama, H., Aug 1989, In : Nippon rinsho. Japanese journal of clinical medicine. 47, 8, p. 1689-1695 7 p.

Research output: Contribution to journal › Article

Calcium Channels

Cell Membrane

Calcium