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Research Output

  • 808 Citations
  • 13 h-Index
  • 37 Article
  • 1 Conference contribution
  • 1 Comment/debate
2020

Necroptosis in pancreatic cancer promotes cancer cell migration and invasion by release of CXCL5

Ando, Y., Ohuchida, K., Otsubo, Y., Kibe, S., Takesue, S., Abe, T., Iwamoto, C., Shindo, K., Moriyama, T., Nakata, K., Miyasaka, Y., Ohtsuka, T., Oda, Y. & Nakamura, M., Jan 1 2020, In : PloS one. 15, 1, e0228015.

Research output: Contribution to journalArticle

Open Access

Neutrophil extracellular traps promote liver micrometastasis in pancreatic ductal adenocarcinoma via the activation of cancer‑associated fibroblasts

Takesue, S., Ohuchida, K., Shinkawa, T., Otsubo, Y., Matsumoto, S., Sagara, A., Yonenaga, A., Ando, Y., Kibe, S., Nakayama, H., Iwamoto, C., Shindo, K., Moriyama, T., Nakata, K., Miyasaka, Y., Ohtsuka, T., Toma, H., Tominaga, Y., Mizumoto, K., Hashizume, M. & 1 others, Nakamura, M., Jan 1 2020, In : International journal of oncology. 56, 2, p. 596-605 10 p.

Research output: Contribution to journalArticle

2019

Adipose tissue-derived stromal cells are sources of cancer-associated fibroblasts and enhance tumor progression by dense collagen matrix

Okumura, T., Ohuchida, K., Kibe, S., Iwamoto, C., Ando, Y., Takesue, S., Nakayama, H., Abe, T., Endo, S., Koikawa, K., Sada, M., Horioka, K., Mochidome, N., Arita, M., Moriyama, T., Nakata, K., Miyasaka, Y., Ohtsuka, T., Mizumoto, K., Oda, Y. & 2 others, Hashizume, M. & Nakamura, M., Mar 15 2019, In : International Journal of Cancer. 144, 6, p. 1401-1413 13 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Cancer-associated acinar-to-ductal metaplasia within the invasive front of pancreatic cancer contributes to local invasion

Kibe, S., Ohuchida, K., Ando, Y., Takesue, S., Nakayama, H., Abe, T., Endo, S., Koikawa, K., Okumura, T., Iwamoto, C., Shindo, K., Moriyama, T., Nakata, K., Miyasaka, Y., Shimamoto, M., Ohtsuka, T., Mizumoto, K., Oda, Y. & Nakamura, M., Mar 1 2019, In : Cancer Letters. 444, p. 70-81 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

CD110 promotes pancreatic cancer progression and its expression is correlated with poor prognosis

Yan, Z., Ohuchida, K., Zheng, B., Okumura, T., Takesue, S., Nakayama, H., Iwamoto, C., Shindo, K., Moriyama, T., Nakata, K., Miyasaka, Y., Ohtsuka, T., Mizumoto, K., Oda, Y., Hashizume, M. & Nakamura, M., May 1 2019, In : Journal of Cancer Research and Clinical Oncology. 145, 5, p. 1147-1164 18 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Development of a pointing device that directly measures the tilt angles of a head

Uchino, S., Nakashima, Y., Moriyama, T., Nakamura, M. & Yamamoto, M., Oct 2019, 2019 IEEE International Conference on Systems, Man and Cybernetics, SMC 2019. Institute of Electrical and Electronics Engineers Inc., p. 2851-2856 6 p. 8913882. (Conference Proceedings - IEEE International Conference on Systems, Man and Cybernetics; vol. 2019-October).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Inhibition of ERK1/2 in cancer-associated pancreatic stellate cells suppresses cancer-stromal interaction and metastasis

Yan, Z., Ohuchida, K., Fei, S., Zheng, B., Guan, W., Feng, H., Kibe, S., Ando, Y., Koikawa, K., Abe, T., Iwamoto, C., Shindo, K., Moriyama, T., Nakata, K., Miyasaka, Y., Ohtsuka, T., Mizumoto, K., Hashizume, M. & Nakamura, M., May 27 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 221.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

S100P regulates the collective invasion of pancreatic cancer cells into the lymphatic endothelial monolayer

Nakayama, H., Yonenaga, A., Sagara, A., Ando, Y., Kibe, S., Takesue, S., Abe, T., Endo, S., Koikawa, K., Okumura, T., Shido, K., Miyoshi, K., Nakata, K., Moriyama, T., Miyasaka, Y., Inoue, S., Ohtsuka, T., Mizumoto, K., Ohuchida, K. & Nakamura, M., Jan 1 2019, In : International journal of oncology. 55, 1, p. 211-222 12 p.

Research output: Contribution to journalArticle

2018

Basement membrane destruction by pancreatic stellate cells leads to local invasion in pancreatic ductal adenocarcinoma

Koikawa, K., Ohuchida, K., Ando, Y., Kibe, S., Nakayama, H., Takesue, S., Endo, S., Abe, T., Okumura, T., Iwamoto, C., Moriyama, T., Nakata, K., Miyasaka, Y., Ohtsuka, T., Nagai, E., Mizumoto, K., Hashizume, M. & Nakamura, M., Jul 1 2018, In : Cancer Letters. 425, p. 65-77 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

International telemedicine activities in Thailand

Shimizu, S., Kudo, K., Tomimatsu, S., Moriyama, T., Moriyama, T., Sadakari, Y., Nakashima, N. & Akaraviputh, T., Sep 1 2018, In : Siriraj Medical Journal. 70, 5, p. 471-475 5 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Metastatic esophageal carcinosarcoma comprising neuroendocrine carcinoma, squamous cell carcinoma, and sarcoma A case report

Tsuchihashi, K., Arita, S., Fujiwara, M., Iwasaki, K., Hirano, A., Yoshihiro, T., Nio, K., Koga, Y., Esaki, M., Ariyama, H., Kusaba, H., Moriyama, T., Ohuchida, K., Nagai, E., Nakamura, M., Oda, Y., Akashi, K. & Baba, E., Oct 1 2018, In : Medicine (United States). 97, 41, e12796.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Pancreatic stellate cells reorganize matrix components and lead pancreatic cancer invasion via the function of Endo180

Koikawa, K., Ohuchida, K., Takesue, S., Ando, Y., Kibe, S., Nakayama, H., Endo, S., Abe, T., Okumura, T., Horioka, K., Sada, M., Iwamoto, C., Moriyama, T., Nakata, K., Miyasaka, Y., Ohuchida, R., Manabe, T., Ohtsuka, T., Nagai, E., Mizumoto, K. & 2 others, Hashizume, M. & Nakamura, M., Jan 1 2018, In : Cancer Letters. 412, p. 143-154 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2017

Autophagy inhibition enhances antiproliferative effect of salinomycin in pancreatic cancer cells

Endo, S., Nakata, K., Sagara, A., Koikawa, K., Ando, Y., Kibe, S., Takesue, S., Nakayama, H., Abe, T., Okumura, T., Moriyama, T., Miyasaka, Y., Ohuchida, K., Ohtsuka, T., Mizumoto, K. & Nakamura, M., Nov 2017, In : Pancreatology. 17, 6, p. 990-996 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Autophagy Is Required for Activation of Pancreatic Stellate Cells, Associated With Pancreatic Cancer Progression and Promotes Growth of Pancreatic Tumors in Mice

Endo, S., Nakata, K., Ohuchida, K., Takesue, S., Nakayama, H., Abe, T., Koikawa, K., Okumura, T., Sada, M., Horioka, K., Zheng, B., Mizuuchi, Y., Iwamoto, C., Murata, M., Moriyama, T., Miyasaka, Y., Ohtsuka, T., Mizumoto, K., Oda, Y., Hashizume, M. & 1 others, Nakamura, M., May 2017, In : Gastroenterology. 152, 6, p. 1492-1506.e24

Research output: Contribution to journalArticle

53 Citations (Scopus)

Cancer-associated peritoneal mesothelial cells lead the formation of pancreatic cancer peritoneal dissemination

Abe, T., Ohuchida, K., Koikawa, K., Endo, S., Okumura, T., Sada, M., Horioka, K., Zheng, B., Moriyama, T., Nakata, K., Miyasaka, Y., Manabe, T., Ohtsuka, T., Nagai, E., Mizumoto, K., Hashizume, M. & Nakamura, M., Feb 2017, In : International journal of oncology. 50, 2, p. 457-467 11 p.

Research output: Contribution to journalArticle

Degree of desmoplasia in metastatic lymph node lesions is associated with lesion size and poor prognosis in pancreatic cancer patients

Nakayama, H., Ohuchida, K., Yoshida, M., Miyazaki, T., Takesue, S., Abe, T., Endo, S., Koikawa, K., Okumura, T., Moriyama, T., Nakata, K., Miyasaka, Y., Shirahane, K., Manabe, T., Ohtsuka, T., Toma, H., Tominaga, Y., Nagai, E., Mizumoto, K., Oda, Y. & 1 others, Nakamura, M., Jan 1 2017, In : Oncology Letters. 14, 3, p. 3141-3147 7 p.

Research output: Contribution to journalArticle

Extra-pancreatic invasion induces lipolytic and fibrotic changes in the adipose microenvironment, with released fatty acids enhancing the invasiveness of pancreatic cancer cells

Okumura, T., Ohuchida, K., Sada, M., Abe, T., Endo, S., Koikawa, K., Iwamoto, C., Miura, D., Mizuuchi, Y., Moriyama, T., Nakata, K., Miyasaka, Y., Manabe, T., Ohtsuka, T., Nagai, E., Mizumoto, K., Oda, Y., Hashizume, M. & Nakamura, M., Jan 1 2017, In : Oncotarget. 8, 11, p. 18280-18295 16 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Five-year Technological Changes of Distant Medical Education in Asia

Kudo, K., Tomimatsu, S., Houkabe, Y., Moriyama, T., Nakashima, N. & Shimizu, S., 2017, In : J Int Soc Telemed eHealth. 5, p. e10

Research output: Contribution to journalArticle

Open Access

インドネシア国内での定例遠隔医療カンファレンス導入に向けた取り組み (JTTA 2017 UTSUNOMIYA 第21回日本遠隔医療学会学術大会)

Translated title of the contribution: Installation of regular medical videoconference inside Indonesia富松俊太, 工藤孔梨子, 波々伯部佳子, 北村泰一, 森山大樹, 麻生暁, 中島直樹 & 清水周次, Sep 2017, In : 日本遠隔医療学会雑誌 = Japanese journal of telemedicine and telecare. 13, 2, p. 120-123 4 p.

Research output: Contribution to journalArticle

国際的な遠隔医療カンファレンス運営のための情報デザイン: イベントプログラム管理システムの構築・公開運用 (JTTA 2017 UTSUNOMIYA 第21回日本遠隔医療学会学術大会)

Translated title of the contribution: Information design for handling international medical teleconference: Development and publication for event programs management system工藤孔梨子, 工藤達郎, 安徳恭彰, 寅田信博, 森山大樹, 中島直樹 & 清水周次, Sep 2017, In : 日本遠隔医療学会雑誌 = Japanese journal of telemedicine and telecare. 13, 2, p. 116-119 4 p.

Research output: Contribution to journalArticle

2016

Feasibility of laparoscopic surgery for complex Crohn's disease of the small intestine

Manabe, T., Ueki, T., Nagayoshi, K., Moriyama, T., Yanai, K., Nagai, S., Esaki, M., Nakamura, K. & Nakamura, M., Nov 1 2016, In : Asian journal of endoscopic surgery. 9, 4, p. 265-269 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Hypoxic stellate cells of pancreatic cancer stroma regulate extracellular matrix fiber organization and cancer cell motility

Sada, M., Ohuchida, K., Horioka, K., Okumura, T., Moriyama, T., Miyasaka, Y., Ohtsuka, T., Mizumoto, K., Oda, Y. & Nakamura, M., Mar 28 2016, In : Cancer Letters. 372, 2, p. 210-218 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Laparoscopic lateral pelvic lymph node dissection is achievable and offers advantages as a minimally invasive surgery over the open approach

Nagayoshi, K., Ueki, T., Manabe, T., Moriyama, T., Yanai, K., Oda, Y. & Tanaka, M., May 1 2016, In : Surgical endoscopy. 30, 5, p. 1938-1947 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Overexpression of microRNA-5100 decreases the aggressive phenotype of pancreatic cancer cells by targeting PODXL

Chijiiwa, Y., Moriyama, T., Ohuchida, K., Nabae, T., Ohtsuka, T., Miyasaka, Y., Fujita, H., Maeyama, R., Mana be, T., Abe, A., Mizuuchi, Y., Oda, Y., Mizumoto, K. & Nakamura, M., Apr 2016, In : International journal of oncology. 48, 4, p. 1688-1700 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Suppression of CD51 in pancreatic stellate cells inhibits tumor growth by reducing stroma and altering tumor-stromal interaction in pancreatic cancer

Horioka, K., Ohuchida, K., Sada, M., Zheng, B., Moriyama, T., Fujita, H., Manabe, T., Ohtsuka, T., Shimamoto, M., Miyazaki, T., Mizumoto, K., Oda, Y. & Nakamura, M., Apr 2016, In : International journal of oncology. 48, 4, p. 1499-1508 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2015

Reduced-port laparoscopic restorative proctocolectomy without diverting ileostomy

Ueki, T., Manabe, T., Nagayoshi, K., Yanai, K., Moriyama, T., Shimizu, S. & Tanaka, M., Nov 1 2015, In : Asian journal of endoscopic surgery. 8, 4, p. 487-490 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

TM4SF1 as a prognostic marker of pancreatic ductal adenocarcinoma is involved in migration and invasion of cancer cells

Zheng, B., Ohuchida, K., Cui, L., Zhao, M., Shindo, K., Fujiwara, K., Manabe, T., Torata, N., Moriyama, T., Miyasaka, Y., Ohtsuka, T., Takahata, S., Mizumoto, K., Oda, Y. & Tanaka, M., Aug 1 2015, In : International journal of oncology. 47, 2, p. 490-498 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2013

How to Prevent Technical Issues in Large Multiparty Medical Videoconferencing

Tomimatsu, S., Kudo, K., Moriyama, T., Tomohiko, M., Taguchi, T. & Shimizu, S., 2013, In : J Int Soc Telemed eHealth. 6, e10, p. 5-8 4 p.

Research output: Contribution to journalArticle

Open Access
2011

MicroRNA expression as a predictive marker for gemcitabine response after surgical resection of pancreatic cancer

Ohuchida, K., Mizumoto, K., Kayashima, T., Fujita, H., Moriyama, T., Ohtsuka, T., Ueda, J., Nagai, E., Hashizume, M. & Tanaka, M., Aug 1 2011, In : Annals of Surgical Oncology. 18, 8, p. 2381-2387 7 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)
2010

CD10+ pancreatic stellate cells enhance the progression of pancreatic cancer

Ikenaga, N., Ohuchida, K., Mizumoto, K., Cui, L., Kayashima, T., Morimatsu, K., Moriyama, T., Nakata, K., Fujita, H. & Tanaka, M., Sep 2010, In : Gastroenterology. 139, 3, p. 1041-1051.e8

Research output: Contribution to journalArticle

109 Citations (Scopus)

Enhanced cell migration and invasion of CD133+ pancreatic cancer cells cocultured with pancreatic stromal cells

Moriyama, T., Ohuchida, K., Mizumoto, K., Cui, L., Ikenaga, N., Sato, N. & Tanaka, M., Jul 15 2010, In : Cancer. 116, 14, p. 3357-3368 12 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Prospectively isolated cancer-associated CD10+fibroblasts have stronger interactions with CD133+colon cancer cells than with CD133-cancer cells

Cui, L., Ohuchida, K., Mizumoto, K., Moriyama, T., Onimaru, M., Nakata, K., Nabae, T., Ueki, T., Sato, N., Tominaga, Y. & Tanaka, M., Oct 19 2010, In : PloS one. 5, 8, e12121.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2009

MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance

Moriyama, T., Ohuchida, K., Mizumoto, K., Yu, J., Sato, N., Nabae, T., Takahata, S., Toma, H., Nagai, E. & Tanaka, M., May 1 2009, In : Molecular Cancer Therapeutics. 8, 5, p. 1067-1074 8 p.

Research output: Contribution to journalArticle

270 Citations (Scopus)

Tumor-stromal interactions with direct cell contacts enhance proliferation of human pancreatic carcinoma cells

Fujita, H., Ohuchida, K., Mizumoto, K., Egami, T., Miyoshi, K., Moriyama, T., Cui, L., Yu, J., Zhao, M., Manabe, T. & Tanaka, M., Dec 1 2009, In : Cancer Science. 100, 12, p. 2309-2317 9 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
2008

Intraoperative parathyroid hormone levels measured by intact and whole parathyroid hormone assays in patients with Graves' disease

Kai, M., Yamashita, H., Cantor, T., Moriyama, T., Rai, M., Ogawa, T., Watanabe, S., Uchino, S. & Noguchi, S., Mar 1 2008, In : Surgery today. 38, 3, p. 214-221 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2005

Intraoperative parathyroid hormone assay in patients with graves' disease for prediction of postoperative tetany

Moriyama, T., Yamashita, H., Noguchi, S., Takamatsu, Y., Ogawa, T., Watanabe, S., Uchino, S., Ohshima, A., Kuroki, S. & Tanaka, M., Oct 1 2005, In : World journal of surgery. 29, 10, p. 1282-1287 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Reelevation of parathyroid hormone level after parathyroidectomy in patients with primary hyperparathyroidism: Importance of decreased renal parathyroid hormone sensitivity

Yamashita, H., Noguchi, S., Moriyama, T., Takamatsu, Y., Sadanaga, K., Uchino, S., Watanabe, S. & Ogawa, T., Apr 2005, In : Surgery. 137, 4, p. 419-425 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Sequential changes in plasma intact and whole parathyroid hormone levels during parathyroidectomy for secondary hyperparathyroidism

Yamashita, H., Cantor, T., Uchino, S., Watanabe, S., Ogawa, T., Moriyama, T., Takamatsu, Y., Fukagawa, M. & Noguchi, S., Feb 1 2005, In : World journal of surgery. 29, 2, p. 169-173 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)