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Fingerprint Dive into the research topics where Takashi Imai is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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C-Type Lectins Medicine & Life Sciences
Macrophages Medicine & Life Sciences
Mucopolysaccharidosis II Medicine & Life Sciences
Enzyme Replacement Therapy Medicine & Life Sciences
Hydronephrosis Medicine & Life Sciences
Mucopolysaccharidosis I Medicine & Life Sciences
Streptococcus Medicine & Life Sciences
Immunity Medicine & Life Sciences

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Research Output 2017 2019

  • 12 Citations
  • 2 h-Index
  • 4 Article
1 Citation (Scopus)

Synthesis of 12- O-Mono- and Diglycosyl-oxystearates, a New Class of Agonists for the C-type Lectin Receptor Mincle

Van Huy, L., Tanaka, C., Imai, T., Yamasaki, S. & Miyamoto, T., Oct 1 2019, In : ACS Medicinal Chemistry Letters. 10, 1, p. 44-49 6 p.

Research output: Contribution to journalArticle

C-Type Lectins
Macrophages
NFATC Transcription Factors
Structure-Activity Relationship
Green Fluorescent Proteins
7 Citations (Scopus)

Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection

Imai, T., Matsumura, T., Mayer-Lambertz, S., Wells, C. A., Ishikawa, E., Butcher, S. K., Barnett, T. C., Walker, M. J., Imamura, A., Ishida, H., Ikebe, T., Miyamoto, T., Ato, M., Ohga, S., Lepenies, B., Van Sorge, N. M. & Yamasaki, S., Nov 6 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 45, p. E10662-E10671

Research output: Contribution to journalArticle

C-Type Lectins
Streptococcus
Immunity
Macrophages
Infection
4 Citations (Scopus)

Dectin-1 intracellular domain determines species-specific ligand spectrum by modulating receptor sensitivity

Takano, T., Motozono, C., Imai, T., Sonoda, K. H., Nakanishi, Y. & Yamasaki, S., Jan 1 2017, In : Journal of Biological Chemistry. 292, 41, p. 16933-16941 9 p.

Research output: Contribution to journalArticle

Ligands
Glucans
C-Type Lectins
dectin 1
Seaweed

Resolution of Hydronephrosis in a Patient With Mucopolysaccharidosis Type II With Enzyme Replacement Therapy

Nishiyama, K., Imai, T., Ohkubo, K., Sanefuji, M. & Takada, H., Mar 1 2017, In : Urology. 101, p. 163-165 3 p.

Research output: Contribution to journalArticle

Mucopolysaccharidosis II
Enzyme Replacement Therapy
Hydronephrosis
Mucopolysaccharidosis I
Iduronate Sulfatase