• 8460 Citations
  • 42 h-Index
1987 …2020

Research output per year

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Research Output

2006

A large-scale full-length cDNA analysis to explore the budding yeast transcriptome

Miura, F., Kawaguchi, N., Sese, J., Toyoda, A., Hattori, M., Morishita, S. & Ito, T., Nov 21 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 47, p. 17846-17851 6 p.

Research output: Contribution to journalArticle

173 Citations (Scopus)

Diverse DNA methylation statuses at alternative promoters of human genes in various tissues

Cheong, J., Yamada, Y., Yamashita, R., Irie, T., Kanai, A., Wakaguri, H., Nakai, K., Ito, T., Saito, I., Sugano, S. & Suzuki, Y., Nov 16 2006, In : DNA Research. 13, 4, p. 155-167 13 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Lessons from comparative analysis of species-specific imprinted genes

Okamura, K. & Ito, T., Mar 1 2006, In : Cytogenetic and Genome Research. 113, 1-4, p. 159-164 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Transcriptional activators in yeast

Titz, B., Thomas, S., Rajagopala, S. V., Chiba, T., Ito, T. & Uetz, P., Mar 20 2006, In : Nucleic acids research. 34, 3, p. 955-967 13 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)
2005

A novel strategy to design highly specific PCR primers based on the stability and uniqueness of 3′-end subsequences

Miura, F., Uematsu, C., Sakaki, Y. & Ito, T., Dec 1 2005, In : Bioinformatics. 21, 24, p. 4363-4370 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Comparative genomics approach toward critical determinants for the imprinting of an evolutionarily conserved gene Impact

Okamura, K., Sakaki, Y. & Ito, T., Apr 15 2005, In : Biochemical and Biophysical Research Communications. 329, 3, p. 824-830 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

The yeast eIF4E-associated protein Eap1p attenuates GCN4 translation upon TOR-inactivation

Matsuo, R., Kubota, H., Obata, T., Kito, K., Ota, K., Kitazono, T., Ibayashi, S., Sasaki, T., Iida, M. & Ito, T., Apr 25 2005, In : FEBS Letters. 579, 11, p. 2433-2438 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2004

A comprehensive analysis of allelic methylation status of CpG islands on human chromosome 21q

Yamada, Y., Watanabe, H., Miura, F., Soejima, H., Uchiyama, M., Iwasaka, T., Mukai, T., Sakaki, Y. & Ito, T., Feb 1 2004, In : Genome Research. 14, 2, p. 247-266 20 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)

Analysis of gene network regulating yeast multidrug resistance by artificial activation of transcription factors: Involvement of Pdr3 in salt tolerance

Onda, M., Ota, K., Chiba, T., Sakaki, Y. & Ito, T., May 12 2004, In : Gene. 332, 1-2, p. 51-59 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

An evolutionary scenario for genomic imprinting of Impact lying between nonimprinted neighbors

Okamura, K., Yamada, Y., Sakaki, Y. & Ito, T., Dec 1 2004, In : DNA Research. 11, 6, p. 381-390 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

An evolutionary scenario for genomic imprinting of Impact lying between nonimprinted neighbors.

Okamura, K., Sakaki, Y. & Ito, T., Dec 2004, In : DNA Research. 11, 6, p. 381-390

Research output: Contribution to journalArticle

A yeast one-hybrid system to detect methylation-dependent DNA-protein interactions

Feng, S. Y., Ota, K., Yamada, Y., Sawabu, N. & Ito, T., Jan 23 2004, In : Biochemical and Biophysical Research Communications. 313, 4, p. 922-925 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Barrier proteins remodel and modify chromatin to restrict silenced domains.

Oki, M., Valenzuela, L., Chiba, T., Ito, T. & Kamakaka, R. T., Mar 2004, In : Molecular and Cellular Biology. 24, 5, p. 1956-1967

Research output: Contribution to journalArticle

81 Citations (Scopus)

Mass spectrometry-based proteomics for quantitative description of cellular events

Kito, K. & Ito, T., Dec 1 2004, In : Current Genomics. 5, 8, p. 629-635 7 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Scaffold protein JSAP1 is transported to growth cones of neurites independent of JNK signaling pathways in PC12h cells

Sato, S., Ito, M., Ito, T. & Yoshioka, K., Mar 31 2004, In : Gene. 329, 1-2, p. 51-60 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

SKIP modifies gene expression by affecting both transcription and splicing

Nagai, K., Yamaguchi, T., Takami, T., Kawasumi, A., Aizawa, M., Masuda, N., Shimizu, M., Tominaga, S., Ito, T., Tsukamoto, T. & Osumi, T., Apr 2 2004, In : Biochemical and Biophysical Research Communications. 316, 2, p. 512-517 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Transcriptomic and proteomic analysis of a 14-3-3 gene-deficient yeast

Ichimura, T., Kubota, H., Goma, T., Mizushima, N., Ohsumi, Y., Iwago, M., Kakiuchi, K., Shekhar, H. U., Shinkawa, T., Taoka, M., Ito, T. & Isobe, T., May 25 2004, In : Biochemistry. 43, 20, p. 6149-6158 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2003

A functional single-nucleotide polymorphism in the human cytidine deaminase gene contributing to ara-C sensitivity

Yue, L., Saikawa, Y., Ota, K., Tanaka, M., Nishimura, R., Uehara, T., Maeba, H., Ito, T., Sasaki, T. & Koizumi, S., Jan 1 2003, In : Pharmacogenetics. 13, 1, p. 29-38 10 p.

Research output: Contribution to journalArticle

101 Citations (Scopus)

Identification of a five-pass transmembrane protein family localizing in the Golgi apparatus and the ER

Shakoori, A., Fujii, G., Yoshimura, S. I., Kitamura, M., Nakayama, K., Ito, T., Ohno, H. & Nakamura, N., Dec 19 2003, In : Biochemical and Biophysical Research Communications. 312, 3, p. 850-857 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Molecular Recognition in Dimerization between PB1 Domains

Noda, Y., Kohjima, M., Izaki, T., Ota, K., Yoshinaga, S., Inagaki, F., Ito, T. & Sumimoto, H., Oct 31 2003, In : Journal of Biological Chemistry. 278, 44, p. 43516-43524 9 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)
168 Citations (Scopus)

Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2α kinase GCN2

Kubota, H., Obata, T., Ota, K., Sasaki, T. & Ito, T., Jun 6 2003, In : Journal of Biological Chemistry. 278, 23, p. 20457-20460 4 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

The PB1 domain and the PC motif-containing region are structurally similar protein binding modules

Yoshinaga, S., Kohjima, M., Ogura, K., Yokochi, M., Takeya, R., Ito, T., Sumimoto, H. & Inagaki, F., Oct 1 2003, In : EMBO Journal. 22, 19, p. 4888-4897 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2002

Erratum: Extraction of knowledge on protein-protein interaction by association rule discovery (Bioinformatics (2002) vol. 18 (705-714))

Oyama, T., Kitano, K., Satou, K. & Ito, T., Aug 1 2002, In : Bioinformatics. 18, 8, 1 p.

Research output: Contribution to journalComment/debate

Extraction of knowledge on protein-protein interaction by association rule discovery

Oyama, T., Kitano, K., Satou, K. & Ito, T., Jan 1 2002, In : Bioinformatics. 18, 5, p. 705-714 10 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

OPR, PC and AID: All in the PB1 family

Ponting, C. P., Ito, T., Moscat, J., Diaz-Meco, M. T., Inagaki, F. & Sumimoto, H., Jan 1 2002, In : Trends in Biochemical Sciences. 27, 1, 1 p.

Research output: Contribution to journalLetter

52 Citations (Scopus)

Roles for the two-hybrid system in exploration of the yeast protein interactome.

Ito, T., Ota, K., Kubota, H., Yamaguchi, Y., Chiba, T., Sakuraba, K. & Yoshida, M., Aug 2002, In : Molecular & cellular proteomics : MCP. 1, 8, p. 561-566 6 p.

Research output: Contribution to journalReview article

96 Citations (Scopus)

The adaptor protein p40 phox as a positive regulator of the superoxide-producing phagocyte oxidase

Kuribayashi, F., Nunoi, H., Wakamatsu, K., Tsunawaki, S., Sato, K., Ito, T. & Sumimoto, H., Dec 2 2002, In : EMBO Journal. 21, 23, p. 6312-6320 9 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)
2001

A comprehensive two-hybrid analysis to explore the yeast protein interactome

Ito, T., Chiba, T., Ozawa, R., Yoshida, M., Hattori, M. & Sakaki, Y., Apr 10 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 8, p. 4569-4574 6 p.

Research output: Contribution to journalArticle

2781 Citations (Scopus)

Budding Yeast GCN1 Binds the GI Domain to Activate the eIF2α Kinase GCN2

Kubota, H., Ota, K., Sakaki, Y. & Ito, T., May 18 2001, In : Journal of Biological Chemistry. 276, 20, p. 17591-17596 6 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Comparative analysis for expressed genes by polymerase chain reaction using module-shuffling primers.

Uematsu, C., Nishida, J., Okano, K., Kambara, H., Miura, F., Ito, T. & Sakaki, Y., Jan 1 2001, In : Nucleic acids research. Supplement (2001). 1, p. 91-92 2 p.

Research output: Contribution to journalArticle

Differential display analysis of mutants for the transcription factor Pdr1p regulating multidrug resistance in the budding yeast

Miura, F., Yada, T., Nakai, K., Sakaki, Y. & Ito, T., Sep 7 2001, In : FEBS Letters. 505, 1, p. 103-108 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Discovery of a novel compound: Insight into mechanisms for acrylamide-induced axonopathy and colchicine-induced apoptotic neuronal cell death

Nakagawa-Yagi, Y., Choi, D. K., Ogane, N., Shimada, S. I., Seya, M., Momoi, T., Ito, T. & Sakaki, Y., Aug 3 2001, In : Brain Research. 909, 1-2, p. 8-19 12 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Exploring the protein interactome using comprehensive two-hybrid projects.

Ito, T., Chiba, T. & Yoshida, M., Jan 1 2001, In : Trends in biotechnology. 19, 10 Suppl

Research output: Contribution to journalReview article

62 Citations (Scopus)

Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C

Noda, Y., Takeya, R., Ohno, S., Naito, S., Ito, T. & Sumimoto, H., Apr 17 2001, In : Genes to Cells. 6, 2, p. 107-119 13 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)

Multiplex polymerase chain reaction (PCR) with color-tagged module-shuffling primers for comparing gene expression levels in various cells

Uematsu, C., Nishida, J., Okano, K., Miura, F., Ito, T., Sakaki, Y. & Kambara, H., Aug 15 2001, In : Nucleic acids research. 29, 16, 1 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Novel modular domain PB1 recognizes pc motif to mediate functional protein-protein interactions

Ito, T., Matsui, Y., Ago, T., Ota, K. & Sumimoto, H., Aug 1 2001, In : EMBO Journal. 20, 15, p. 3938-3946 9 p.

Research output: Contribution to journalArticle

126 Citations (Scopus)

Solution structure of the PX domain, a target of the SH3 domain

Hiroaki, H., Ago, T., Ito, T., Sumimoto, H. & Kohda, D., Jun 21 2001, In : Nature Structural Biology. 8, 6, p. 526-530 5 p.

Research output: Contribution to journalArticle

141 Citations (Scopus)

Structure and ligand recognition of the PB1 domain: A novel protein module binding to the PC motif

Terasawa, H., Noda, Y., Ito, T., Hatanaka, H., Ichikawa, S., Ogura, K., Sumimoto, H. & Inagaki, F., Aug 1 2001, In : EMBO Journal. 20, 15, p. 3947-3956 10 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

The PX domain as a novel phosphoinositide-binding module

Ago, T., Takeya, R., Hiroaki, H., Kuribayashi, F., Ito, T., Kohda, D. & Sumimoto, H., Sep 28 2001, In : Biochemical and Biophysical Research Communications. 287, 3, p. 733-738 6 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)
2000

A new ETV6/TEL partner gene, ARG (ABL-related gene or ABL2), identified in an AML-M3 cell line with a t(1;12)(q25;p13) translocation

Iijima, Y., Ito, T., Oikawa, T., Eguchi, M., Eguchi-Ishimae, M., Kamada, N., Kishi, K., Asano, S., Sakaki, Y. & Sato, Y., Mar 15 2000, In : Blood. 95, 6, p. 2126-2131 6 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

A novel G-protein-coupled receptor gene expressed in striatum

Mizushima, K., Miyamoto, Y., Tsukahara, F., Hirai, M., Sakaki, Y. & Ito, T., Nov 1 2000, In : Genomics. 69, 3, p. 314-321 8 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Comparative genome analysis of the mouse imprinted gene Impact and its nonimprinted human homolog IMPACT: Toward the structural basis for species-specific imprinting

Okamura, K., Hagiwara-Takeuchi, Y., Li, T., Vu, T. H., Hirai, M., Hattori, M., Sakaki, Y., Hoffman, A. R. & Ito, T., Dec 1 2000, In : Genome Research. 10, 12, p. 1878-1889 12 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)
41 Citations (Scopus)
641 Citations (Scopus)
1999

Developmentally-regulated expression of mNapor encoding an apoptosis-induced ELAV-type RNA binding protein

Choi, D. K., Ito, T., Tsukahara, F., Hirai, M. & Sakaki, Y., Sep 3 1999, In : Gene. 237, 1, p. 135-142 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Fluorescent differential display: A fast and reliable method for message display polymerase chain reaction

Ito, T. & Sakaki, Y., Jan 1 1999, In : Methods in enzymology. 303, p. 298-309 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Spatiotemporal, allelic, and enforced expression of Ximpact, the Xenopus homolog of mouse imprinted gene Impact

Yamada, Y., Hagiwara, Y., Shiokawa, K., Sakaki, Y. & Ito, T., Mar 5 1999, In : Biochemical and Biophysical Research Communications. 256, 1, p. 162-169 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
1998
67 Citations (Scopus)