• 8577 Citations
  • 42 h-Index
1987 …2020

Research output per year

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Research Output

Absolute quantification of the budding yeast transcriptome by means of competitive PCR between genomic and complementary DNAs

Miura, F., Kawaguchi, N., Yoshida, M., Uematsu, C., Kito, K., Sakaki, Y. & Ito, T., Nov 29 2008, In : BMC genomics. 9, 574.

Research output: Contribution to journalArticle

50 Citations (Scopus)

A comprehensive analysis of allelic methylation status of CpG islands on human chromosome 11q: Comparison with chromosome 21q

Yamada, Y., Shirakawa, T., Taylor, T. D., Okamura, K., Soejima, H., Uchiyama, M., Iwasaka, T., Mukai, T., Muramoto, K. I., Sakaki, Y. & Ito, T., Aug 2006, In : DNA Sequence - Journal of DNA Sequencing and Mapping. 17, 4, p. 300-306 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A comprehensive analysis of allelic methylation status of CpG islands on human chromosome 21q

Yamada, Y., Watanabe, H., Miura, F., Soejima, H., Uchiyama, M., Iwasaka, T., Mukai, T., Sakaki, Y. & Ito, T., Feb 2004, In : Genome Research. 14, 2, p. 247-266 20 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)

A comprehensive two-hybrid analysis to explore the yeast protein interactome

Ito, T., Chiba, T., Ozawa, R., Yoshida, M., Hattori, M. & Sakaki, Y., Apr 10 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 8, p. 4569-4574 6 p.

Research output: Contribution to journalArticle

2800 Citations (Scopus)

Activation of the phagocyte NADPH oxidase

Takeshige, K., Ito, T. & Sumimoto, H., 1996, In : Journal of Toxicological Sciences. 21, 5, p. 291-292 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Affinity capture electrophoresis for sequence-specific DNA purification.

Ito, T., Smith, C. L. & Cantor, C. R., Jun 1992, In : Genetic Analysis Techniques and Applications. 9, 3, p. 96-99

Research output: Contribution to journalArticle

8 Citations (Scopus)

A functional single-nucleotide polymorphism in the human cytidine deaminase gene contributing to ara-C sensitivity

Yue, L., Saikawa, Y., Ota, K., Tanaka, M., Nishimura, R., Uehara, T., Maeba, H., Ito, T., Sasaki, T. & Koizumi, S., Jan 2003, In : Pharmacogenetics. 13, 1, p. 29-38 10 p.

Research output: Contribution to journalArticle

101 Citations (Scopus)

A large-scale full-length cDNA analysis to explore the budding yeast transcriptome

Miura, F., Kawaguchi, N., Sese, J., Toyoda, A., Hattori, M., Morishita, S. & Ito, T., Nov 21 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 47, p. 17846-17851 6 p.

Research output: Contribution to journalArticle

175 Citations (Scopus)

Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging

Miura, F., Enomoto, Y., Dairiki, R. & Ito, T., Sep 2012, In : Nucleic acids research. 40, 17, p. e136

Research output: Contribution to journalArticle

175 Citations (Scopus)

Analysis of chromosome 21--construction of STS map and its application for contig map construction

Sakaki, Y., Hattori, M., Tanahashi, H., Ito, T. & Tashiro, K., Feb 1993, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 38, 3, p. 260-267 8 p.

Research output: Contribution to journalReview article

Analysis of gene network regulating yeast multidrug resistance by artificial activation of transcription factors: Involvement of Pdr3 in salt tolerance

Onda, M., Ota, K., Chiba, T., Sakaki, Y. & Ito, T., May 12 2004, In : Gene. 332, 1-2, p. 51-59 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

An evolutionary scenario for genomic imprinting of Impact lying between nonimprinted neighbors

Okamura, K., Yamada, Y., Sakaki, Y. & Ito, T., 2004, In : DNA Research. 11, 6, p. 381-390 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

An evolutionary scenario for genomic imprinting of Impact lying between nonimprinted neighbors.

Okamura, K., Sakaki, Y. & Ito, T., Dec 2004, In : DNA Research. 11, 6, p. 381-390

Research output: Contribution to journalArticle

A new ETV6/TEL partner gene, ARG (ABL-related gene or ABL2), identified in an AML-M3 cell line with a t(1;12)(q25;p13) translocation

Iijima, Y., Ito, T., Oikawa, T., Eguchi, M., Eguchi-Ishimae, M., Kamada, N., Kishi, K., Asano, S., Sakaki, Y. & Sato, Y., Mar 15 2000, In : Blood. 95, 6, p. 2126-2131 6 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)
7 Citations (Scopus)
68 Citations (Scopus)
29 Citations (Scopus)

A novel G-protein-coupled receptor gene expressed in striatum

Mizushima, K., Miyamoto, Y., Tsukahara, F., Hirai, M., Sakaki, Y. & Ito, T., Nov 1 2000, In : Genomics. 69, 3, p. 314-321 8 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

A novel procedure for selective cloning of Noti linking fragments from mammalian genomes

Ito, T. & Sakaki, Y., Oct 11 1988, In : Nucleic acids research. 16, 19, p. 9177-9184 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

A novel strategy to design highly specific PCR primers based on the stability and uniqueness of 3′-end subsequences

Miura, F., Uematsu, C., Sakaki, Y. & Ito, T., Dec 1 2005, In : Bioinformatics. 21, 24, p. 4363-4370 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

An SH3 domain-mediated interaction between the phagocyte NADPH oxidase factors p40phox and p47phox

Ito, T., Nakamura, R., Sumimoto, H., Takeshige, K. & Sakaki, Y., May 6 1996, In : FEBS Letters. 385, 3, p. 229-232 4 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

A nuclear factor which interacts with an at-cluster in the first intron of rat α2-macroglobulin gene

Ito, T. & Sakaki, Y., Sep 15 1987, In : Biochemical and Biophysical Research Communications. 147, 2, p. 824-830 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A parallel affinity purification method for selective isolation of polyubiquitinated proteins

Ota, K., Kito, K., Iemura, S. I., Natsume, T. & Ito, T., Aug 1 2008, In : Proteomics. 8, 15, p. 3004-3007 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A proteomic screen reveals the mitochondrial outer membrane protein Mdm34p as an essential target of the F-box protein Mdm30p

Ota, K., Kito, K., Okada, S. & Ito, T., 2008, In : Genes to Cells. 13, 10, p. 1075-1085 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Assembly and activation of the phagocyte NADPH oxidase: Specific interaction of the N-terminal Src homology 3 domain of p47(phox) with p22(phox) is required for activation of the NADPH oxidase

Sumimoto, H., Hata, K., Mizuki, K., Ito, T., Kage, Y., Sakaki, Y., Fukumaki, Y., Nakamura, M. & Takeshige, K., 1996, In : Journal of Biological Chemistry. 271, 36, p. 22152-22158 7 p.

Research output: Contribution to journalArticle

152 Citations (Scopus)

A strategy for absolute proteome quantification with mass spectrometry by hierarchical use of peptide-concatenated standards

Kito, K., Okada, M., Ishibashi, Y., Okada, S. & Ito, T., May 1 2016, In : Proteomics. 16, 10, p. 1457-1473 17 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

A synthetic protein approach toward accurate mass spectrometric quantification of component stoichiometry of multiprotein complexes

Kito, K., Ota, K., Fujita, T. & Ito, T., Feb 1 2007, In : Journal of Proteome Research. 6, 2, p. 792-800 9 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

ATF7-Dependent Epigenetic Changes Are Required for the Intergenerational Effect of a Paternal Low-Protein Diet

Yoshida, K., Maekawa, T., Ly, N. H., Fujita, S. I., Muratani, M., Ando, M., Katou, Y., Araki, H., Miura, F., Shirahige, K., Okada, M., Ito, T., Chatton, B. & Ishii, S., May 7 2020, In : Molecular Cell. 78, 3, p. 445-458.e6

Research output: Contribution to journalArticle

2 Citations (Scopus)

A yeast one-hybrid system to detect methylation-dependent DNA-protein interactions

Feng, S. Y., Ota, K., Yamada, Y., Sawabu, N. & Ito, T., Jan 23 2004, In : Biochemical and Biophysical Research Communications. 313, 4, p. 922-925 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

A yeast one-hybrid system to screen for methylated DNA-binding proteins

Feng, S. Y., Ota, K. & Ito, T., Nov 2010, In : Nucleic acids research. 38, 20, p. e189

Research output: Contribution to journalArticle

8 Citations (Scopus)

Barrier proteins remodel and modify chromatin to restrict silenced domains.

Oki, M., Valenzuela, L., Chiba, T., Ito, T. & Kamakaka, R. T., Mar 2004, In : Molecular and Cellular Biology. 24, 5, p. 1956-1967

Research output: Contribution to journalArticle

81 Citations (Scopus)

Base-Resolution Methylome of Retinal Pigment Epithelial Cells Used in the First Trial of Human Induced Pluripotent Stem Cell-Based Autologous Transplantation

Araki, H., Miura, F., Watanabe, A., Morinaga, C., Kitaoka, F., Kitano, Y., Sakai, N., Shibata, Y., Terada, M., Goto, S., Yamanaka, S., Takahashi, M. & Ito, T., Oct 8 2019, In : Stem Cell Reports. 13, 4, p. 761-774 14 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Base-resolution methylomes of gliomas bearing histone H3.3 mutations reveal a G34 mutant-specific signature shared with bone tumors

Sangatsuda, Y., Miura, F., Araki, H., Mizoguchi, M., Hata, N., Kuga, D., Hatae, R., Akagi, Y., Amemiya, T., Fujioka, Y., Arai, Y., Yoshida, A., Shibata, T., Yoshimoto, K., Iihara, K. & Ito, T., Sep 30 2020, In : Scientific reports. 10, 1, p. 16162

Research output: Contribution to journalArticle

Budding Yeast GCN1 Binds the GI Domain to Activate the eIF2α Kinase GCN2

Kubota, H., Ota, K., Sakaki, Y. & Ito, T., May 18 2001, In : Journal of Biological Chemistry. 276, 20, p. 17591-17596 6 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Changepoint detection in base-resolution methylome data reveals a robust signature of methylated domain landscape

Yokoyama, T., Miura, F., Araki, H., Okamura, K. & Ito, T., Aug 12 2015, In : BMC genomics. 16, 1, 594.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Circular permutation of ligand-binding module improves dynamic range of genetically encoded FRET-based nanosensor

Okada, S., Ota, K. & Ito, T., Dec 2009, In : Protein Science. 18, 12, p. 2518-2527 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Comparative analysis for expressed genes by polymerase chain reaction using module-shuffling primers.

Uematsu, C., Nishida, J., Okano, K., Kambara, H., Miura, F., Ito, T. & Sakaki, Y., Jan 1 2001, In : Nucleic acids research. Supplement (2001). 1, p. 91-92 2 p.

Research output: Contribution to journalArticle

Comparative genome analysis of the mouse imprinted gene Impact and its nonimprinted human homolog IMPACT: Toward the structural basis for species-specific imprinting

Okamura, K., Hagiwara-Takeuchi, Y., Li, T., Vu, T. H., Hirai, M., Hattori, M., Sakaki, Y., Hoffman, A. R. & Ito, T., 2000, In : Genome Research. 10, 12, p. 1878-1889 12 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Comparative genomics approach toward critical determinants for the imprinting of an evolutionarily conserved gene Impact

Okamura, K., Sakaki, Y. & Ito, T., Apr 15 2005, In : Biochemical and Biophysical Research Communications. 329, 3, p. 824-830 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Detecting protein – DNA interactions using a modified yeast one-hybrid system

Ota, K., Feng, S. Y. & Ito, T., 2014, In : Methods in Molecular Biology. 1164, p. 39-50 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Developmentally-regulated expression of mNapor encoding an apoptosis-induced ELAV-type RNA binding protein

Choi, D. K., Ito, T., Tsukahara, F., Hirai, M. & Sakaki, Y., Sep 3 1999, In : Gene. 237, 1, p. 135-142 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Differential display analysis of gene expression in developing embryos of Xenopus laevis

Adati, N., Ito, T., Koga, C., Kito, K., Sakaki, Y. & Shiokawa, K., May 17 1995, In : BBA - Gene Structure and Expression. 1262, 1, p. 43-51 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Differential display analysis of mutants for the transcription factor Pdr1p regulating multidrug resistance in the budding yeast

Miura, F., Yada, T., Nakai, K., Sakaki, Y. & Ito, T., Sep 7 2001, In : FEBS Letters. 505, 1, p. 103-108 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Differentially expressed MHC class II-associated invariant chain in rat stomach pyloric mucosa with N-methyl-N'-nitro-N-nitrosoguanidine exposure

Furihata, C., Oka, M., Yamamoto, M., Ito, T., Ichinose, M., Miki, K., Tatematsu, M., Sakaki, Y. & Reske, K., 1997, In : Cancer Research. 57, 8, p. 1416-1418 3 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Discovery of a novel compound: Insight into mechanisms for acrylamide-induced axonopathy and colchicine-induced apoptotic neuronal cell death

Nakagawa-Yagi, Y., Choi, D. K., Ogane, N., Shimada, S. I., Seya, M., Momoi, T., Ito, T. & Sakaki, Y., Aug 3 2001, In : Brain Research. 909, 1-2, p. 8-19 12 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Discrimination between stable and dynamic components of protein complexes by means of quantitative proteomics

Kito, K., Kawaguchi, N., Okada, S. & Ito, T., Jun 1 2008, In : Proteomics. 8, 12, p. 2366-2370 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Diverse DNA methylation statuses at alternative promoters of human genes in various tissues

Cheong, J., Yamada, Y., Yamashita, R., Irie, T., Kanai, A., Wakaguri, H., Nakai, K., Ito, T., Saito, I., Sugano, S. & Suzuki, Y., 2006, In : DNA Research. 13, 4, p. 155-167 13 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

DMS-seq for In Vivo Genome-Wide Mapping of Protein-DNA Interactions and Nucleosome Centers

Umeyama, T. & Ito, T., Jul 2018, In : Current Protocols in Molecular Biology. 123, 1, e60.

Research output: Contribution to journalArticle

DMS-Seq for In Vivo Genome-wide Mapping of Protein-DNA Interactions and Nucleosome Centers

Umeyama, T. & Ito, T., Oct 3 2017, In : Cell Reports. 21, 1, p. 289-300 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

DNA methylation and gene expression in Mimulus guttatus

Colicchio, J. M., Miura, F., Kelly, J. K., Ito, T. & Hileman, L. C., Jul 7 2015, In : BMC genomics. 16, 1, 507.

Research output: Contribution to journalArticle

13 Citations (Scopus)