• 8436 Citations
  • 42 h-Index
1987 …2019

Research output per year

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Research Output

Epigenetic landscape influences the liver cancer genome architecture

Hama, N., Totoki, Y., Miura, F., Tatsuno, K., Saito-Adachi, M., Nakamura, H., Arai, Y., Hosoda, F., Urushidate, T., Ohashi, S., Mukai, W., Hiraoka, N., Aburatani, H., Ito, T. & Shibata, T., Dec 1 2018, In : Nature communications. 9, 1, 1643.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Epigenome mapping of human normal purified hepatocytes: Personal epigenome variation and genome-epigenome correlation

Arai, E., Miura, F., Totoki, Y., Yamashita, S., Tian, Y., Gotoh, M., Ojima, H., Nakagawa, H., Takahashi, Y., Nakamura, H., Hama, N., Kato, M., Kimura, H., Suzuki, Y., Ito, T., Shibata, T. & Kanai, Y., Jul 2018, In : Epigenomics. 10, 7, p. 955-979 25 p.

Research output: Contribution to journalArticle

Erratum: Extraction of knowledge on protein-protein interaction by association rule discovery (Bioinformatics (2002) vol. 18 (705-714))

Oyama, T., Kitano, K., Satou, K. & Ito, T., Aug 1 2002, In : Bioinformatics. 18, 8, 1 p.

Research output: Contribution to journalComment/debate

Erratum: The adaptor protein p40phox as a positive regulator of the superoxide-producing phagocyte oxidase (EMBO Journal (2002) 21 (6312-6320) DOI 10.1093/emboj/cdf642)

Kuribayashi, F., Nunoi, H., Wakamatsu, K., Tsunawaki, S., Sato, K., Ito, T. & Sumimoto, H., Feb 1 2016, In : EMBO Journal. 35, 3, p. 369-370 2 p.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

Exploring the protein interactome using comprehensive two-hybrid projects.

Ito, T., Chiba, T. & Yoshida, M., Jan 1 2001, In : Trends in biotechnology. 19, 10 Suppl

Research output: Contribution to journalReview article

62 Citations (Scopus)

Expression of the α 2 -macroglobulin-encoding gene in rat brain and cultured astrocytes

Higuchi, M., Ito, T., Imai, Y., Iwaki, T., Hattori, M., Kohsaka, S., Niho, Y. & Sakaki, Y., Apr 20 1994, In : Gene. 141, 2, p. 155-162 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Extraction of knowledge on protein-protein interaction by association rule discovery

Oyama, T., Kitano, K., Satou, K. & Ito, T., Jan 1 2002, In : Bioinformatics. 18, 5, p. 705-714 10 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Fluorescent differential display: A fast and reliable method for message display polymerase chain reaction

Ito, T. & Sakaki, Y., Jan 1 1999, In : Methods in enzymology. 303, p. 298-309 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Fluorescent differential display: Arbitrarily primed RT-PCR fingerprinting on an automated DNA sequencer

Ito, T., Kito, K., Adati, N., Mitsui, Y., Hagiwara, H. & Sakaki, Y., Sep 5 1994, In : FEBS Letters. 351, 2, p. 231-236 6 p.

Research output: Contribution to journalArticle

184 Citations (Scopus)

Fluorescent differential display.

Ito, T. & Sakaki, Y., Jan 1 1997, In : Methods in molecular biology (Clifton, N.J.). 85, p. 37-44 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Fluorescent differential display analysis of gene expression in apoptotic neuroblastoma cells

Choi, D. K., Ito, T., Mitsui, Y. & Sakaki, Y., Nov 26 1998, In : Gene. 223, 1-2, p. 21-31 11 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Fluorescent differential display analysis of gene expression in differentiating neuroblastoma cells

Kito, K., Ito, T. & Sakaki, Y., Jan 3 1997, In : Gene. 184, 1, p. 73-81 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Fluorescent differential display method for high-speed scanning of tissue- or cell-specific transcripts

Ito, T. & Sakaki, Y., Dec 1 1996, In : Methods in Molecular Genetics. 8, C, p. 229-245 17 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Functional modules and expression of mouse p40(phox) and p67(phox), SH3- domain-containing proteins involved in the phagocyte NADPH oxidase complex

Mizuki, K., Kadomatsu, K., Hata, K., Ito, T., Fan, Q. W., Kage, Y., Fukumaki, Y., Sakaki, Y., Takeshige, K. & Sumimoto, H., Feb 1 1998, In : European Journal of Biochemistry. 251, 3, p. 573-582 10 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)
41 Citations (Scopus)

Highly efficient PCR assay to discriminate allelic DNA methylation status using whole genome amplification

Yamada, Y. & Ito, T., Jun 14 2011, In : BMC research notes. 4, 179.

Research output: Contribution to journalArticle

2 Citations (Scopus)
Open Access
1 Citation (Scopus)

Highly sensitive targeted methylome sequencing by post-bisulfite adaptor tagging

Miura, F. & Ito, T., Jan 1 2015, In : DNA Research. 22, 1, p. 13-18 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

High-resolution DNA methylome analysis of primordial germ cells identifies gender-specific reprogramming in mice

Kobayashi, H., Sakurai, T., Miura, F., Imai, M., Mochiduki, K., Yanagisawa, E., Sakashita, A., Wakai, T., Suzuki, Y., Ito, T., Matsui, Y. & Kono, T., Apr 1 2013, In : Genome Research. 23, 4, p. 616-627 12 p.

Research output: Contribution to journalArticle

156 Citations (Scopus)

High-throughput fluorescence labelling of full-length cDNA products based on a reconstituted translation system

Kawahashi, Y., Doi, N., Oishi, Y., Tsuda, C., Takashima, H., Baba, T., Mori, H., Ito, T. & Yanagawa, H., Jan 1 2007, In : Journal of biochemistry. 141, 1, p. 19-24 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C

Noda, Y., Takeya, R., Ohno, S., Naito, S., Ito, T. & Sumimoto, H., Apr 17 2001, In : Genes to Cells. 6, 2, p. 107-119 13 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)

Identification of a five-pass transmembrane protein family localizing in the Golgi apparatus and the ER

Shakoori, A., Fujii, G., Yoshimura, S. I., Kitamura, M., Nakayama, K., Ito, T., Ohno, H. & Nakamura, N., Dec 19 2003, In : Biochemical and Biophysical Research Communications. 312, 3, p. 850-857 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Involvement of dendritic cell response to resistance of stomach carcinogenesis caused by N-methyl-N'-nitro-N-nitrosoguanidine in rats

Oka, M., Furihata, C., Kitoh, K., Yamamoto, M., Tatematsu, M., Ichinose, M., Miki, K., Ito, T., Sakaki, Y. & Reske, K., Sep 15 1998, In : Cancer Research. 58, 18, p. 4107-4112 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Isolation and expression study of a maternally expressed novel xenopus gene Xem1 encoding a putative evolutionarily conserved membrane protein

Adati, N., Ito, T., Sakaki, Y. & Shiokawa, K., Sep 29 1997, In : Biochemical and Biophysical Research Communications. 238, 3, p. 899-904 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Lessons from comparative analysis of species-specific imprinted genes

Okamura, K. & Ito, T., Mar 1 2006, In : Cytogenetic and Genome Research. 113, 1-4, p. 159-164 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

MafB protein stability is regulated by the JNK and ubiquitin-proteasome pathways

Tanahashi, H., Kito, K., Ito, T. & Yoshioka, K., Feb 1 2010, In : Archives of Biochemistry and Biophysics. 494, 1, p. 94-100 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Mapping of histone-binding sites in histone replacement-completed spermatozoa

Yoshida, K., Muratani, M., Araki, H., Miura, F., Suzuki, T., Dohmae, N., Katou, Y., Shirahige, K., Ito, T. & Ishii, S., Dec 1 2018, In : Nature communications. 9, 1, 3885.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Mapping of regions of physical deletion on chromosome 16q in prostate cancer cells by fluorescence in situ hybridization (FISH).

Cher, M. L., Ito, T., Weidner, N., Carroll, P. R. & Jensen, R. H., Jan 1995, In : Journal of Urology. 153, 1, p. 249-254

Research output: Contribution to journalArticle

64 Citations (Scopus)

Mass spectrometry-based approaches toward absolute quantitative proteomics

Kito, K. & Ito, T., Jun 1 2008, In : Current Genomics. 9, 4, p. 263-274 12 p.

Research output: Contribution to journalReview article

69 Citations (Scopus)

Mass spectrometry-based proteomics for quantitative description of cellular events

Kito, K. & Ito, T., Dec 1 2004, In : Current Genomics. 5, 8, p. 629-635 7 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Maternal protein restriction alters the renal ptger1 DNA methylation state in SHRSP offspring

Miyoshi, M., Sato, M., Saito, K., Otani, L., Shirahige, K., Miura, F., Ito, T., Jia, H. & Kato, H., Oct 5 2018, In : Nutrients. 10, 10, 1436.

Research output: Contribution to journalArticle

Mediator cyclin-dependent kinases upregulate transcription of inflammatory genes in cooperation with NF-κB and C/EBPβ on stimulation of Toll-like receptor 9

Yamamoto, S., Hagihara, T., Horiuchi, Y., Okui, A., Wani, S., Yoshida, T., Inoue, T., Tanaka, A., Ito, T., Hirose, Y. & Ohkuma, Y., Mar 1 2017, In : Genes to Cells. 22, 3, p. 265-276 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Methods for protein-protein interaction analysis

Kito, K. & Ito, T., Dec 1 2007, Introduction to Systems Biology. Humana Press, p. 160-182 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Methods for systematic scanning of gene expression

Ito, T., Jan 1 1997, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 42, 17 Suppl, p. 2981-2986 6 p.

Research output: Contribution to journalReview article

Molecular Recognition in Dimerization between PB1 Domains

Noda, Y., Kohjima, M., Izaki, T., Ota, K., Yoshinaga, S., Inagaki, F., Ito, T. & Sumimoto, H., Oct 31 2003, In : Journal of Biological Chemistry. 278, 44, p. 43516-43524 9 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Mouse Oocyte Methylomes at Base Resolution Reveal Genome-Wide Accumulation of Non-CpG Methylation and Role of DNA Methyltransferases

Shirane, K., Toh, H., Kobayashi, H., Miura, F., Chiba, H., Ito, T., Kono, T. & Sasaki, H., Apr 1 2013, In : PLoS genetics. 9, 4, e1003439.

Research output: Contribution to journalArticle

156 Citations (Scopus)

Multiplex polymerase chain reaction (PCR) with color-tagged module-shuffling primers for comparing gene expression levels in various cells

Uematsu, C., Nishida, J., Okano, K., Miura, F., Ito, T., Sakaki, Y. & Kambara, H., Aug 15 2001, In : Nucleic acids research. 29, 16, 1 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

NMR structure of the heterodimer of Bem1 and Cdc24 PB1 domains from Saccharomyces cerevisiae.

Ogura, K., Tandai, T., Yoshinaga, S., Kobashigawa, Y., Kumeta, H., Ito, T., Sumimoto, H. & Inagaki, F., Sep 2009, In : Journal of biochemistry. 146, 3, p. 317-325 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Novel modular domain PB1 recognizes pc motif to mediate functional protein-protein interactions

Ito, T., Matsui, Y., Ago, T., Ota, K. & Sumimoto, H., Aug 1 2001, In : EMBO Journal. 20, 15, p. 3938-3946 9 p.

Research output: Contribution to journalArticle

126 Citations (Scopus)

Nuclear factors interacting with an interleukin-6 responsive element of rat α2-macroglobulin gene

Ito, T., Tanahashi, H., Musumi, Y. & Sakaki, Y., Nov 25 1989, In : Nucleic acids research. 17, 22, p. 9425-9435 11 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Nuclear matrix association regions of rat α2-macroglobulin gene

Ito, T. & Sakaki, Y., Dec 16 1987, In : Biochemical and Biophysical Research Communications. 149, 2, p. 449-454 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

OPR, PC and AID: All in the PB1 family

Ponting, C. P., Ito, T., Moscat, J., Diaz-Meco, M. T., Inagaki, F. & Sumimoto, H., Jan 1 2002, In : Trends in Biochemical Sciences. 27, 1, 1 p.

Research output: Contribution to journalLetter

52 Citations (Scopus)
168 Citations (Scopus)

Photoprotein aequorin: use as a reporter enzyme in studying gene expression in mammalian cells

Tanahashi, H., Ito, T., Inouye, S., Tsuji, F. I. & Sakaki, Y., Dec 15 1990, In : Gene. 96, 2, p. 249-255 7 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion

Matsuda, T., Irie, T., Katsurabayashi, S., Hayashi, Y., Nagai, T., Hamazaki, N., Adefuin, A. M. D., Miura, F., Ito, T., Kimura, H., Shirahige, K., Takeda, T., Iwasaki, K., Imamura, T. & Nakashima, K., Feb 6 2019, In : Neuron. 101, 3, p. 472-485.e7

Research output: Contribution to journalArticle

14 Citations (Scopus)

Post-bisulfite adaptor tagging for PCR-free whole-genome bisulfite sequencing

Miura, F. & Ito, T., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 123-136 14 p. (Methods in Molecular Biology; vol. 1708).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Proteomic analysis of in vivo 14-3-3 interactions in the yeast Saccharomyces cerevisiae

Kakiuchi, K., Yamauchi, Y., Taoka, M., Iwago, M., Fujita, T., Ito, T., Song, S. Y., Sakai, A., Isobe, T. & Ichimura, T., Jul 3 2007, In : Biochemistry. 46, 26, p. 7781-7792 12 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Pulsed‐field polyacrylamide gel electrophoresis: Basic phenomena and applications

Ito, T., Hohjoh, H. & Sakaki, Y., Jan 1 1993, In : ELECTROPHORESIS. 14, 1, p. 278-282 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2α kinase GCN2

Kubota, H., Obata, T., Ota, K., Sasaki, T. & Ito, T., Jun 6 2003, In : Journal of Biological Chemistry. 278, 23, p. 20457-20460 4 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)