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Research Output 1987 2019

5 Citations (Scopus)

Unexpected complexity of the budding yeast transcriptome

Ito, T., Miura, F. & Onda, M., Dec 1 2008, In : IUBMB Life. 60, 12, p. 775-781 7 p.

Research output: Contribution to journalReview article

Saccharomycetales
Transcriptome
Yeast
Genes
Genome
14 Citations (Scopus)

Triplex affinity capture of a single copy clone from a yeast genomic library.

Ito, T., Smith, C. L. & Cantor, C. R., Jul 1992, In : Nucleic Acids Research. 20, 13, p. 3524

Research output: Contribution to journalArticle

2 Citations (Scopus)

Triazole linking for preparation of a next-generation sequencing library from single-stranded DNA

Miura, F., Fujino, T., Kogashi, K., Shibata, Y., Miura, M., Isobe, H. & Ito, T., Sep 19 2018, In : Nucleic acids research. 46, 16, p. e95

Research output: Contribution to journalArticle

Open Access
Triazoles
Azides
Single-Stranded DNA
Ligation
Alkynes
22 Citations (Scopus)

Translation initiation: A regulatory role for poly(A) tracts in front of the AUG codon in saccharomyces cerevisiae

Xia, X., Mackay, V., Yao, X., Wu, J., Miura, F., Ito, T. & Morris, D. R., Oct 1 2011, In : Genetics. 189, 2, p. 469-478 10 p.

Research output: Contribution to journalArticle

Poly A
Codon
Saccharomyces cerevisiae
Untranslated Regions
Yeasts
32 Citations (Scopus)

Transcriptomic and proteomic analysis of a 14-3-3 gene-deficient yeast

Ichimura, T., Kubota, H., Goma, T., Mizushima, N., Ohsumi, Y., Iwago, M., Kakiuchi, K., Shekhar, H. U., Shinkawa, T., Taoka, M., Ito, T. & Isobe, T., May 25 2004, In : Biochemistry. 43, 20, p. 6149-6158 10 p.

Research output: Contribution to journalArticle

Proteomics
Yeast
Genes
Yeasts
Saccharomyces cerevisiae
69 Citations (Scopus)

Transcriptional activators in yeast

Titz, B., Thomas, S., Rajagopala, S. V., Chiba, T., Ito, T. & Uetz, P., Mar 20 2006, In : Nucleic acids research. 34, 3, p. 955-967 13 p.

Research output: Contribution to journalArticle

Transcriptional Activation
Helix-Loop-Helix Motifs
Yeasts
Fungal Proteins
Asparagine
6 Citations (Scopus)

Toward genome-wide scanning of gene expression: A functional aspect of the Genome Project

Ito, T. & Sakaki, Y., 1996, In : Essays in Biochemistry. 31, p. 11-21 11 p.

Research output: Contribution to journalArticle

Gene expression
Genes
Genome
Scanning
Gene Expression
639 Citations (Scopus)
Protein Interaction Maps
Saccharomycetales
Fungal Proteins
Clone Cells
Saccharomyces cerevisiae Proteins
17 Citations (Scopus)

The yeast eIF4E-associated protein Eap1p attenuates GCN4 translation upon TOR-inactivation

Matsuo, R., Kubota, H., Obata, T., Kito, K., Ota, K., Kitazono, T., Ibayashi, S., Sasaki, T., Iida, M. & Ito, T., Apr 25 2005, In : FEBS Letters. 579, 11, p. 2433-2438 6 p.

Research output: Contribution to journalArticle

Sirolimus
Yeast
Yeasts
Proteins
Amino Acids
22 Citations (Scopus)

The WD40 protein Morg1 facilitates Par6-aPKC binding to Crb3 for apical identity in epithelial cells

Hayase, J., Kamakura, S., Iwakiri, Y., Yamaguchi, Y., Izaki, T., Ito, T. & Sumimoto, H., Mar 1 2013, In : Journal of Cell Biology. 200, 5, p. 635-650 16 p.

Research output: Contribution to journalArticle

Epithelial Cells
Proteins
Tight Junctions
Cysts
Madin Darby Canine Kidney Cells
85 Citations (Scopus)

The PX domain as a novel phosphoinositide-binding module

Ago, T., Takeya, R., Hiroaki, H., Kuribayashi, F., Ito, T., Kohda, D. & Sumimoto, H., Sep 28 2001, In : Biochemical and Biophysical Research Communications. 287, 3, p. 733-738 6 p.

Research output: Contribution to journalArticle

Phosphatidylinositols
Endosomes
Phagocytes
Oxidoreductases
Proteins
69 Citations (Scopus)

The PC motif: A novel and evolutionarily conserved sequence involved in interaction between p40(phox) and p67(phox), SH3 domain-containing cytosolic factors of the phagocyte NADPH oxidase

Nakamura, R., Sumimoto, H., Mizuki, K., Hata, K., Ago, T., Kitajima, S., Takeshige, K., Sakaki, Y. & Ito, T., Feb 1 1998, In : European Journal of Biochemistry. 251, 3, p. 583-589 7 p.

Research output: Contribution to journalArticle

Conserved Sequence
NADPH Oxidase
Phagocytes
Mutagenesis
Amphiphiles
30 Citations (Scopus)

The PB1 domain and the PC motif-containing region are structurally similar protein binding modules

Yoshinaga, S., Kohjima, M., Ogura, K., Yokochi, M., Takeya, R., Ito, T., Sumimoto, H. & Inagaki, F., Oct 1 2003, In : EMBO Journal. 22, 19, p. 4888-4897 10 p.

Research output: Contribution to journalArticle

Ubiquitin
Protein Binding
Amino Acid Motifs
Saccharomycetales
Static Electricity
11 Citations (Scopus)

The AP-1 transcription factor JunB is required for Th17 cell differentiation

Yamazaki, S., Tanaka, Y., Araki, H., Kohda, A., Sanematsu, F., Arasaki, T., Duan, X., Miura, F., Katagiri, T., Shindo, R., Nakano, H., Ito, T., Fukui, Y., Endo, S. & Sumimoto, H., Dec 1 2017, In : Scientific reports. 7, 1, 17402.

Research output: Contribution to journalArticle

Th17 Cells
Transcription Factor AP-1
Cell Differentiation
Helper-Inducer T-Lymphocytes
Autoimmune Experimental Encephalomyelitis
118 Citations (Scopus)

The adaptor protein p40 phox as a positive regulator of the superoxide-producing phagocyte oxidase

Kuribayashi, F., Nunoi, H., Wakamatsu, K., Tsunawaki, S., Sato, K., Ito, T. & Sumimoto, H., Dec 2 2002, In : EMBO Journal. 21, 23, p. 6312-6320 9 p.

Research output: Contribution to journalArticle

Phagocytes
Superoxides
Oxidoreductases
Proteins
Membranes
19 Citations (Scopus)
Synthetic Genes
S-Adenosylmethionine
Gene Regulatory Networks
Metabolites
Yeast
9 Citations (Scopus)

Structure of the rat α2-macroglobulin-coding gene

Hattori, M., Kusakabe, S., Ohgusu, H., Tsuchiya, Y., Ito, T. & Sakaki, Y., Apr 30 1989, In : Gene. 77, 2, p. 333-340 8 p.

Research output: Contribution to journalArticle

Macroglobulins
Exons
Genes
Complementary DNA
Clone Cells
57 Citations (Scopus)

Structure and ligand recognition of the PB1 domain: A novel protein module binding to the PC motif

Terasawa, H., Noda, Y., Ito, T., Hatanaka, H., Ichikawa, S., Ogura, K., Sumimoto, H. & Inagaki, F., Aug 1 2001, In : EMBO Journal. 20, 15, p. 3947-3956 10 p.

Research output: Contribution to journalArticle

Protein Binding
Cell Polarity
Ligands
Proteins
Nuclear magnetic resonance
97 Citations (Scopus)
Protein Interaction Domains and Motifs
Amoeba
Fungi
Animals
NADPH Oxidase
13 Citations (Scopus)

Spatiotemporal, allelic, and enforced expression of Ximpact, the Xenopus homolog of mouse imprinted gene Impact

Yamada, Y., Hagiwara, Y., Shiokawa, K., Sakaki, Y. & Ito, T., Mar 5 1999, In : Biochemical and Biophysical Research Communications. 256, 1, p. 162-169 8 p.

Research output: Contribution to journalArticle

Xenopus
Yeast
Genes
Gene encoding
Polymorphism
139 Citations (Scopus)

Solution structure of the PX domain, a target of the SH3 domain

Hiroaki, H., Ago, T., Ito, T., Sumimoto, H. & Kohda, D., 2001, In : Nature Structural Biology. 8, 6, p. 526-530 5 p.

Research output: Contribution to journalArticle

src Homology Domains
Proline
Proteins
NADPH Oxidase
Phagocytes
8 Citations (Scopus)

Software updates in the illumina hiseq platform affect whole-genome bisulfite sequencing

Toh, H., Shirane, K., Miura, F., Kubo, N., Ichiyanagi, K., Hayashi, K., Saitou, M., Suyama, M., Ito, T. & Sasaki, H., Jan 5 2017, In : BMC Genomics. 18, 1, 31.

Research output: Contribution to journalArticle

Software
Genome
Methylation
Libraries
DNA
12 Citations (Scopus)

SKIP modifies gene expression by affecting both transcription and splicing

Nagai, K., Yamaguchi, T., Takami, T., Kawasumi, A., Aizawa, M., Masuda, N., Shimizu, M., Tominaga, S., Ito, T., Tsukamoto, T. & Osumi, T., Apr 2 2004, In : Biochemical and Biophysical Research Communications. 316, 2, p. 512-517 6 p.

Research output: Contribution to journalArticle

RNA Splice Sites
Transcription
Reporter Genes
Gene expression
Introns
8 Citations (Scopus)

Sixty new STSs (sequence-tagged sites) of human chromosome 21

Tanahashi, H., Ito, T., Hattori, M., Ohira, M., Ohki, M., Tashiro, K. & Sakaki, Y., Jan 1 1994, In : DNA Research. 1, 2, p. 85-89 5 p.

Research output: Contribution to journalArticle

Sequence Tagged Sites
Chromosomes, Human, Pair 21
Human Chromosomes
Clone Cells
Libraries
10 Citations (Scopus)

Sequence-tagged NotI sites of human chromosome 21: Sequence analysis and mapping

Hattori, M., Toyoda, A., Ichikawa, H., Ito, T., Ohgusu, H., Oishi, N., Kano, T., Kuhara, S., Ohki, M. & Sakaki, Y., Jul 1993, In : Genomics. 17, 1, p. 39-44 6 p.

Research output: Contribution to journalArticle

Sequence Tagged Sites
Chromosomes, Human, Pair 21
Human Chromosomes
Sequence Analysis
Clone Cells
110 Citations (Scopus)

Sequence-specific DNA purification by triplex affinity capture.

Ito, T., Smith, C. L. & Cantor, C. R., Jan 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 2, p. 495-498

Research output: Contribution to journalArticle

78 Citations (Scopus)

Screening for imprinted genes by allelic message display: Identification of a paternally expressed gene Impact on mouse chromosome 18

Hagiwara, Y., Hirai, M., Nishiyama, K., Kanazawa, I., Ueda, T., Sakaki, Y. & Ito, T., Aug 19 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 17, p. 9249-9254 6 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 18
Genes
Fungal Proteins
Bacterial Proteins
Organism Cloning

Screening for imprinted genes by allelic message display

Hagiwara, Y. & Ito, T., Jan 1 1997, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 42, 17 Suppl, p. 2864-2868 5 p.

Research output: Contribution to journalReview article

Genetic Transcription
Genomic Imprinting
Gene Expression Regulation
Genetic Testing
Alleles
24 Citations (Scopus)

Scaffold protein JSAP1 is transported to growth cones of neurites independent of JNK signaling pathways in PC12h cells

Sato, S., Ito, M., Ito, T. & Yoshioka, K., Mar 31 2004, In : Gene. 329, 1-2, p. 51-60 10 p.

Research output: Contribution to journalArticle

Growth Cones
JNK Mitogen-Activated Protein Kinases
Neurites
Kinesin
Proteins
96 Citations (Scopus)

Roles for the two-hybrid system in exploration of the yeast protein interactome.

Ito, T., Ota, K., Kubota, H., Yamaguchi, Y., Chiba, T., Sakuraba, K. & Yoshida, M., Aug 2002, In : Molecular & cellular proteomics : MCP. 1, 8, p. 561-566 6 p.

Research output: Contribution to journalReview article

Fungal Proteins
Hybrid systems
Two-Hybrid System Techniques
Proteins
Yeast
6 Citations (Scopus)

Remodeling of the SCF complex-mediated ubiquitination system by compositional alteration of incorporated F-box proteins

Kato, M., Kito, K., Ota, K. & Ito, T., Jan 1 2010, In : Proteomics. 10, 1, p. 115-123 9 p.

Research output: Contribution to journalArticle

SKP Cullin F-Box Protein Ligases
F-Box Proteins
Ubiquitination
Substrates
Isotope Labeling
9 Citations (Scopus)

Regulation of N-cadherin-based cell-cell interaction by JSAP1 scaffold in PC12h cells

Bayarsaikhan, M., Takino, T., Gantulga, D., Sato, H., Ito, T. & Yoshioka, K., Feb 9 2007, In : Biochemical and Biophysical Research Communications. 353, 2, p. 357-362 6 p.

Research output: Contribution to journalArticle

Cadherins
Scaffolds
Cell Communication
Nerve Growth Factor
Cells
14 Citations (Scopus)

Regional DNA methylation differences between humans and chimpanzees are associated with genetic changes, transcriptional divergence and disease genes

Fukuda, K., Ichiyanagi, K., Yamada, Y., Go, Y., Udono, T., Wada, S., Maeda, T., Soejima, H., Saitou, N., Ito, T. & Sasaki, H., Jul 1 2013, In : Journal of Human Genetics. 58, 7, p. 446-454 9 p.

Research output: Contribution to journalArticle

Pan troglodytes
Hominidae
DNA Methylation
Methylation
Gene Expression
18 Citations (Scopus)

Rare occurrence of ras and p53 gene mutations in mouse stomach tumors induced by N-methyl-N-nitrosourea

Furihata, C., Tatematsu, M., Saito, M., Ishida, S., Nakanishi, H., Inada, K. I., Tei, H., Hattori, M., Ito, T. & Sakaki, Y., Jan 1 1997, In : Japanese Journal of Cancer Research. 88, 4, p. 363-368 6 p.

Research output: Contribution to journalArticle

Methylnitrosourea
ras Genes
p53 Genes
Stomach
Adenocarcinoma
80 Citations (Scopus)

Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2α kinase GCN2

Kubota, H., Obata, T., Ota, K., Sasaki, T. & Ito, T., Jun 6 2003, In : Journal of Biological Chemistry. 278, 23, p. 20457-20460 4 p.

Research output: Contribution to journalArticle

Sirolimus
Transfer RNA
Phosphotransferases
Chemical activation
Messenger RNA
10 Citations (Scopus)

Pulsed‐field polyacrylamide gel electrophoresis: Basic phenomena and applications

Ito, T., Hohjoh, H. & Sakaki, Y., Jan 1 1993, In : ELECTROPHORESIS. 14, 1, p. 278-282 5 p.

Research output: Contribution to journalArticle

Electrophoresis
Polyacrylamide Gel Electrophoresis
Buffers
Gels
Circular DNA
56 Citations (Scopus)

Proteomic analysis of in vivo 14-3-3 interactions in the yeast Saccharomyces cerevisiae

Kakiuchi, K., Yamauchi, Y., Taoka, M., Iwago, M., Fujita, T., Ito, T., Song, S. Y., Sakai, A., Isobe, T. & Ichimura, T., Jul 3 2007, In : Biochemistry. 46, 26, p. 7781-7792 12 p.

Research output: Contribution to journalArticle

Cell signaling
Proteomics
Yeast
Saccharomyces cerevisiae
Chitin
2 Citations (Scopus)

Post-bisulfite adaptor tagging for PCR-free whole-genome bisulfite sequencing

Miura, F. & Ito, T., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 123-136 14 p. (Methods in Molecular Biology; vol. 1708).

Research output: Chapter in Book/Report/Conference proceedingChapter

Genome
Polymerase Chain Reaction
Genomic Library
DNA
hydrogen sulfite
12 Citations (Scopus)

Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion

Matsuda, T., Irie, T., Katsurabayashi, S., Hayashi, Y., Nagai, T., Hamazaki, N., Adefuin, A. M. D., Miura, F., Ito, T., Kimura, H., Shirahige, K., Takeda, T., Iwasaki, K., Imamura, T. & Nakashima, K., Feb 6 2019, In : Neuron. 101, 3, p. 472-485.e7

Research output: Contribution to journalArticle

Microglia
Epigenomics
Neurons
Transcription Factors
Genes
40 Citations (Scopus)

Photoprotein aequorin: use as a reporter enzyme in studying gene expression in mammalian cells

Tanahashi, H., Ito, T., Inouye, S., Tsuji, F. I. & Sakaki, Y., Dec 15 1990, In : Gene. 96, 2, p. 249-255 7 p.

Research output: Contribution to journalArticle

Luminescent Proteins
Aequorin
Gene Expression
Enzymes
Human Herpesvirus 1
166 Citations (Scopus)
src Homology Domains
NADPH Oxidase
Phagocytes
Phosphatidylinositols
Oxidoreductases
52 Citations (Scopus)

OPR, PC and AID: All in the PB1 family

Ponting, C. P., Ito, T., Moscat, J., Diaz-Meco, M. T., Inagaki, F. & Sumimoto, H., Jan 1 2002, In : Trends in Biochemical Sciences. 27, 1, 1 p.

Research output: Contribution to journalLetter

Proto-Oncogene Proteins
Saccharomyces cerevisiae Proteins
Guanine Nucleotide Exchange Factors
Cell Cycle Proteins
Viral Proteins
13 Citations (Scopus)

Nuclear matrix association regions of rat α2-macroglobulin gene

Ito, T. & Sakaki, Y., Dec 16 1987, In : Biochemical and Biophysical Research Communications. 149, 2, p. 449-454 6 p.

Research output: Contribution to journalArticle

Nuclear Matrix
Macroglobulins
Introns
Rats
Genes
43 Citations (Scopus)

Nuclear factors interacting with an interleukin-6 responsive element of rat α2-macroglobulin gene

Ito, T., Tanahashi, H., Musumi, Y. & Sakaki, Y., Nov 25 1989, In : Nucleic acids research. 17, 22, p. 9425-9435 11 p.

Research output: Contribution to journalArticle

Macroglobulins
Interleukin-6
Acute-Phase Proteins
Genes
Conserved Sequence
124 Citations (Scopus)

Novel modular domain PB1 recognizes pc motif to mediate functional protein-protein interactions

Ito, T., Matsui, Y., Ago, T., Ota, K. & Sumimoto, H., Aug 1 2001, In : EMBO Journal. 20, 15, p. 3938-3946 9 p.

Research output: Contribution to journalArticle

Proteins
Saccharomycetales
Fungal Proteins
NADPH Oxidase
Phagocytes
11 Citations (Scopus)

NMR structure of the heterodimer of Bem1 and Cdc24 PB1 domains from Saccharomyces cerevisiae.

Ogura, K., Tandai, T., Yoshinaga, S., Kobashigawa, Y., Kumeta, H., Ito, T., Sumimoto, H. & Inagaki, F., Jan 1 2009, In : Journal of biochemistry. 146, 3, p. 317-325 9 p.

Research output: Contribution to journalArticle

Cell Polarity
Saccharomycetales
Static Electricity
Hydrophobic and Hydrophilic Interactions
Isotopes
5 Citations (Scopus)

Multiplex polymerase chain reaction (PCR) with color-tagged module-shuffling primers for comparing gene expression levels in various cells

Uematsu, C., Nishida, J., Okano, K., Miura, F., Ito, T., Sakaki, Y. & Kambara, H., Aug 15 2001, In : Nucleic acids research. 29, 16, 1 p.

Research output: Contribution to journalArticle

Multiplex Polymerase Chain Reaction
Color
Gene Expression
Electrophoresis
Gels
152 Citations (Scopus)

Mouse Oocyte Methylomes at Base Resolution Reveal Genome-Wide Accumulation of Non-CpG Methylation and Role of DNA Methyltransferases

Shirane, K., Toh, H., Kobayashi, H., Miura, F., Chiba, H., Ito, T., Kono, T. & Sasaki, H., Apr 1 2013, In : PLoS genetics. 9, 4, e1003439.

Research output: Contribution to journalArticle

methyltransferases
Methyltransferases
methylation
DNA Methylation
Methylation
67 Citations (Scopus)

Molecular Recognition in Dimerization between PB1 Domains

Noda, Y., Kohjima, M., Izaki, T., Ota, K., Yoshinaga, S., Inagaki, F., Ito, T. & Sumimoto, H., Oct 31 2003, In : Journal of Biological Chemistry. 278, 44, p. 43516-43524 9 p.

Research output: Contribution to journalArticle

Molecular recognition
Dimerization
Lysine
Proteins
Coulomb interactions

Methods for systematic scanning of gene expression

Ito, T., Jan 1 1997, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 42, 17 Suppl, p. 2981-2986 6 p.

Research output: Contribution to journalReview article

Nucleic Acid Hybridization
Genetic Techniques
DNA Sequence Analysis
Genome
Gene Expression