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Research Output 2012 2019

  • 818 Citations
  • 14 h-Index
  • 30 Article
  • 4 Review article
2019

B lymphocytes directly contribute to tissue fibrosis in patients with IgG4-related disease

Della-Torre, E., Rigamonti, E., Perugino, C., Baghai-Sain, S., Sun, N., Kaneko, N., maehara, T., Rovati, L., Ponzoni, M., Milani, R., Lanzillotta, M., Mahajan, V., Mattoo, H., Molineris, I., Deshpande, V., Stone, J. H., Falconi, M., Manfredi, A. A. & Pillai, S., Jan 1 2019, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Fibrosis
B-Lymphocytes
Immunoglobulin G
Fibroblasts
Wound Healing

CD206+ tumor-associated macrophages promote proliferation and invasion in oral squamous cell carcinoma via EGF production

Haque, A. S. M. R., Moriyama, M., Kubota, K., Ishiguro, N., Sakamoto, M., Chinju, A., Mochizuki, K., Sakamoto, T., Kaneko, N., Munemura, R., Maehara, T., Tanaka, A., Hayashida, J. N., Kawano, S., Kiyoshima, T. & Nakamura, S., Dec 1 2019, In : Scientific reports. 9, 1, 14611.

Research output: Contribution to journalArticle

Open Access
Epidermal Growth Factor
Squamous Cell Carcinoma
Macrophages
Neoplasms
Conditioned Culture Medium

Clinical features and mechanistic insights regarding IgG4-related dacryoadenitis and sialoadenitis: a review

maehara, T., Pillai, S., Stone, J. H. & Nakamura, S., Jul 1 2019, In : International Journal of Oral and Maxillofacial Surgery. 48, 7, p. 908-916 9 p.

Research output: Contribution to journalReview article

Dacryocystitis
Sialadenitis
Immunoglobulin G
Immunoglobulins
T-Lymphocytes

Osteoid osteoma of mandibular bone: Case report and review of the literature

maehara, T., Murakami, Y., Kawano, S., Mikami, Y., Kiyoshima, T., Chikui, T., Kakizoe, N., Munemura, R. & Nakamura, S., Sep 1 2019, In : Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 31, 5, p. 322-326 5 p.

Research output: Contribution to journalArticle

Osteoid Osteoma
Bone and Bones
Non-Steroidal Anti-Inflammatory Agents
Osteoblasts
Pain
2 Citations (Scopus)

Pathogenesis of IgG4-related disease: a critical review

maehara, T., Moriyama, M. & Nakamura, S., Apr 15 2019, In : Odontology. 107, 2, p. 127-132 6 p.

Research output: Contribution to journalReview article

Immunoglobulins
T-Lymphocytes
Fibrosis
B-Lymphocytes
Phlebitis

The diagnostic utility of submandibular gland sonography and labial salivary gland biopsy in IgG4-related dacryoadenitis and sialadenitis: Its potential application to the diagnostic criteria

Sakamoto, M., Moriyama, M., Shimizu, M., Chinju, A., Mochizuki, K., Munemura, R., Ohyama, K., maehara, T., Ogata, K., Ohta, M., Yamauchi, M., Ishiguro, N., Matsumura, M., Ohyama, Y., Kiyoshima, T. & Nakamura, S., Jan 1 2019, In : Modern Rheumatology.

Research output: Contribution to journalArticle

Dacryocystitis
Sialadenitis
Submandibular Gland
Lip
Salivary Glands
2018
7 Citations (Scopus)

High-frequency, functional HIV-specific T-follicular helper and regulatory cells are present within germinal centers in children but not adults

Roider, J., maehara, T., Ngoepe, A., Ramsuran, D., Muenchhoff, M., Adland, E., Aicher, T., Kazer, S. W., Jooste, P., Karim, F., Kuhn, W., Shalek, A. K., Ndung'u, T., Morris, L., Moore, P. L., Pillai, S., Kløverpris, H., Goulder, P. & Leslie, A., Sep 12 2018, In : Frontiers in Immunology. 9, SEP, 1975.

Research output: Contribution to journalArticle

Germinal Center
Regulatory T-Lymphocytes
Helper-Inducer T-Lymphocytes
Lymphoid Tissue
Neutralizing Antibodies
7 Citations (Scopus)

The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo

Maehara, T., Mattoo, H., Mahajan, V. S., Murphy, S. J. H., Yuen, G. J., Ishiguro, N., Ohta, M., Moriyama, M., Saeki, T., Yamamoto, H., Yamauchi, M., Daccache, J., Kiyoshima, T., Nakamura, S., Stone, J. H. & Pillai, S., Jan 1 2018, In : Life Science Alliance. 1, 1, e201800050.

Research output: Contribution to journalArticle

Immunoglobulin Class Switching
interleukin-4
Helper-Inducer T-Lymphocytes
Interleukin-4
Immunoglobulin G
2017
29 Citations (Scopus)

CD163 + CD204 + tumor-associated macrophages contribute to T cell regulation via interleukin-10 and PD-L1 production in oral squamous cell carcinoma

Kubota, K., Moriyama, M., Furukawa, S., Rafiul, H. A. S. M., Maruse, Y., Jinno, T., Tanaka, A., Ohta, M., Ishiguro, N., Yamauchi, M., Sakamoto, M., maehara, T., Jun-Nosuke, H., Kawano, S., Kiyoshima, T. & Nakamura, S., Dec 1 2017, In : Scientific reports. 7, 1, 1755.

Research output: Contribution to journalArticle

Interleukin-10
Squamous Cell Carcinoma
Macrophages
T-Lymphocytes
Neoplasms
12 Citations (Scopus)

Emerging Treatment Models in Rheumatology: IgG4-Related Disease: Insights Into Human Immunology and Targeted Therapies

Perugino, C. A., Mattoo, H., Mahajan, V. S., maehara, T., Wallace, Z. S., Pillai, S. & Stone, J. H., Sep 1 2017, In : Arthritis and Rheumatology. 69, 9, p. 1722-1732 11 p.

Research output: Contribution to journalReview article

Rheumatology
Allergy and Immunology
Immunoglobulin G
Therapeutics
3 Citations (Scopus)
Immunoglobulin G
B-Lymphocytes
Immunoglobulin Class Switching
Antigens
Phlebitis
24 Citations (Scopus)

Interleukin-33 produced by M2 macrophages and other immune cells contributes to Th2 immune reaction of IgG4-related disease

Furukawa, S., Moriyama, M., Miyake, K., Nakashima, H., Tanaka, A., Maehara, T., Iizuka-Koga, M., Tsuboi, H., Hayashida, J. N., Ishiguro, N., Yamauchi, M., Sumida, T. & Nakamura, S., Feb 13 2017, In : Scientific reports. 7, 42413.

Research output: Contribution to journalArticle

Immunoglobulin G
Macrophages
Germinal Center
Salivary Glands
Epithelial Cells
51 Citations (Scopus)

Lesional CD4+ IFN-γ+ cytotoxic T lymphocytes in IgG4-related dacryoadenitis and sialoadenitis

maehara, T., Mattoo, H., Ohta, M., Mahajan, V. S., Moriyama, M., Yamauchi, M., Drijvers, J., Nakamura, S., Stone, J. H. & Pillai, S. S., Feb 1 2017, In : Annals of the Rheumatic Diseases. 76, 2, p. 377-385 9 p.

Research output: Contribution to journalArticle

Dacryocystitis
Sialadenitis
T-cells
Cytotoxic T-Lymphocytes
Interferon-gamma
4 Citations (Scopus)

Myeloid dendritic cells stimulated by thymic stromal lymphopoietin promote Th2 immune responses and the pathogenesis of oral lichen planus

Yamauchi, M., Moriyama, M., Jun-Nosuke, H., maehara, T., Ishiguro, N., Kubota, K., Furukawa, S., Ohta, M., Sakamoto, M., Tanaka, A. & Nakamura, S., Mar 1 2017, In : PloS one. 12, 3, e0173017.

Research output: Contribution to journalArticle

Oral Lichen Planus
Myeloid Cells
dendritic cells
Dendritic Cells
lichens
2016
92 Citations (Scopus)

Clonal expansion of CD4+ cytotoxic T lymphocytes in patients with IgG4-related disease

Mattoo, H., Mahajan, V. S., maehara, T., Deshpande, V., Della-Torre, E., Wallace, Z. S., Kulikova, M., Drijvers, J. M., Daccache, J., Carruthers, M. N., Castelino, F. V., Stone, J. R., Stone, J. H. & Pillai, S., Sep 1 2016, In : Journal of Allergy and Clinical Immunology. 138, 3, p. 825-838 14 p.

Research output: Contribution to journalArticle

Cytotoxic T-Lymphocytes
Immunoglobulin G
Interleukin-1
Flow Cytometry
T-Cell Receptor Genes
8 Citations (Scopus)

DNA microarray analysis of submandibular glands in IgG4-related disease indicates a role for MARCO and other innate immune-related proteins

Ohta, M., Moriyama, M., Maehara, T., Gion, Y., Furukawa, S., Tanaka, A., Hayashida, J. N., Yamauchi, M., Ishiguro, N., Mikami, Y., Tsuboi, H., Iizuka-Koga, M., Kawano, S., Sato, Y., Kiyoshima, T., Sumida, T. & Nakamura, S., Jan 1 2016, In : Medicine (United States). 95, 7, p. e2853

Research output: Contribution to journalArticle

Submandibular Gland
Microarray Analysis
Oligonucleotide Array Sequence Analysis
Immunoglobulin G
Macrophages
8 Citations (Scopus)

Molecular analysis of fungal populations in patients with oral candidiasis using next-generation sequencing

Imabayashi, Y., Moriyama, M., Takeshita, T., Ieda, S., Hayashida, J. N., Tanaka, A., Maehara, T., Furukawa, S., Ohta, M., Kubota, K., Yamauchi, M., Ishiguro, N., Yamashita, Y. & Nakamura, S., Jun 16 2016, In : Scientific reports. 6, 28110.

Research output: Contribution to journalArticle

Oral Candidiasis
Biodiversity
Population
Candida
Culture Techniques
9 Citations (Scopus)

The diagnostic utility of labial salivary gland biopsy in IgG4-related disease

Moriyama, M., Ohta, M., Furukawa, S., Mikami, Y., Tanaka, A., maehara, T., Yamauchi, M., Ishiguro, N., Hayashida, J. N., Kawano, S., Ohyama, Y., Kiyoshima, T. & Nakamura, S., Sep 2 2016, In : Modern Rheumatology. 26, 5, p. 725-729 5 p.

Research output: Contribution to journalArticle

Lip
Salivary Glands
Immunoglobulin G
Biopsy
Lymphoma
2015
6 Citations (Scopus)

A case of mantle cell lymphoma presenting as IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease

Hayashi, Y., Moriyama, M., maehara, T., Goto, Y., Kawano, S., Ohta, M., Tanaka, A., Furukawa, S., Jun-Nosuke, H., Kiyoshima, T., Shimizu, M., Chikui, T. & Nakamura, S., Jul 25 2015, In : World Journal of Surgical Oncology. 13, 1, 225.

Research output: Contribution to journalArticle

Mikulicz' Disease
Dacryocystitis
Sialadenitis
Mantle-Cell Lymphoma
Immunoglobulin G
11 Citations (Scopus)

A case of marginal zone B cell lymphoma mimicking IgG4-related dacryoadenitis and sialoadenitis

Ohta, M., Moriyama, M., Goto, Y., Kawano, S., Tanaka, A., maehara, T., Furukawa, S., Jun-Nosuke, H., Kiyoshima, T., Shimizu, M., Arinobu, Y. & Nakamura, S., Feb 21 2015, In : World Journal of Surgical Oncology. 13, 1, 67.

Research output: Contribution to journalArticle

Dacryocystitis
Sialadenitis
Marginal Zone B-Cell Lymphoma
Immunoglobulin G
Lymphoma
7 Citations (Scopus)

Clinical relevance of Küttner tumour and IgG4-related dacryoadenitis and sialoadenitis

Furukawa, S., Moriyama, M., Kawano, S., Tanaka, A., maehara, T., Jun-Nosuke, H., Goto, Y., Kiyoshima, T., Shiratsuchi, H., Ohyama, Y., Ohta, M., Imabayashi, Y. & Nakamura, S., Mar 1 2015, In : Oral Diseases. 21, 2, p. 257-262 6 p.

Research output: Contribution to journalArticle

Dacryocystitis
Sialadenitis
Immunoglobulin G
Neoplasms
Plasma Cells
3 Citations (Scopus)

Cytokine profiles contribute to understanding the pathogenic difference between good syndrome and oral lichen planus

maehara, T., Moriyama, M., Kawano, S., Jun-Nosuke, H., Furukawa, S., Ohta, M., Tanaka, A., Yamauchi, M., Ohyama, Y., Kiyoshima, T. & Nakamura, S., Apr 6 2015, In : Medicine (United States). 94, 14

Research output: Contribution to journalArticle

Oral Lichen Planus
Cytokines
Mouth Mucosa
T-Lymphocytes
B-Lymphocytes
2 Citations (Scopus)

Differences of stimulated and unstimulated salivary flow rates in patients with dry mouth

Jun-Nosuke, H., Minami, S., Moriyama, M., Toyoshima, T., Shinozaki, S., Tanaka, A., maehara, T. & Nakamura, S., Jan 1 2015, In : Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 27, 1, p. 96-101 6 p.

Research output: Contribution to journalArticle

Mouth
Visual Analog Scale
Gingiva
Deglutition
Drinking Water
51 Citations (Scopus)

Preferential M2 macrophages contribute to fibrosis in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease

Furukawa, S., Moriyama, M., Tanaka, A., maehara, T., Tsuboi, H., Iizuka, M., Jun-Nosuke, H., Ohta, M., Saeki, T., Notohara, K., Sumida, T. & Nakamura, S., Jan 1 2015, In : Clinical Immunology. 156, 1, p. 9-18 10 p.

Research output: Contribution to journalArticle

Mikulicz' Disease
Dacryocystitis
Sialadenitis
Fibrosis
Immunoglobulin G
18 Citations (Scopus)

Saliva as a potential tool for diagnosis of dry mouth including Sjögren's syndrome

Oyama, K., Moriyama, M., Jun-Nosuke, H., Tanaka, A., maehara, T., Ieda, S., Furukawa, S., Ohta, M., Imabayashi, Y. & Nakamura, S., Jan 1 2015, In : Oral Diseases. 21, 2, p. 224-231 8 p.

Research output: Contribution to journalArticle

Saliva
Mouth
Xerostomia
Chromogranin A
Secretory Immunoglobulin A
2014
9 Citations (Scopus)

Molecular analysis of fungal populations in patients with oral candidiasis using internal transcribed spacer region

Ieda, S., Moriyama, M., Takashita, T., maehara, T., Imabayashi, Y., Shinozaki, S., Tanaka, A., Jun-Nosuke, H., Furukawa, S., Ohta, M., Yamashita, Y. & Nakamura, S., Jun 30 2014, In : PloS one. 9, 6, e101156.

Research output: Contribution to journalArticle

Oral Candidiasis
candidiasis
Fungi
internal transcribed spacers
mouth
30 Citations (Scopus)
Mikulicz' Disease
Dacryocystitis
Sialadenitis
Lip
Salivary Glands
41 Citations (Scopus)

T helper subsets in Sjögren's syndrome and IgG4-related dacryoadenitis and sialoadenitis: A critical review

Moriyama, M., Tanaka, A., maehara, T., Furukawa, S., Nakashima, H. & Nakamura, S., Jan 1 2014, In : Journal of Autoimmunity. 51, p. 81-88 8 p.

Research output: Contribution to journalReview article

Dacryocystitis
Sialadenitis
Immunoglobulin G
Mikulicz' Disease
T-Lymphocyte Subsets
2013
20 Citations (Scopus)

Clinical characteristics of Mikulicz's disease as an IgG4-related disease

Moriyama, M., Tanaka, A., maehara, T., Ohyama, Y., Shimizu, M., Nakashima, H., Jun-Nosuke, H., Shinozaki, S., Kubo, Y., Furukawa, S., Kikuta, T. & Nakamura, S., Dec 1 2013, In : Clinical Oral Investigations. 17, 9, p. 1995-2002 8 p.

Research output: Contribution to journalArticle

Mikulicz' Disease
Immunoglobulin G
Sialography
Germinal Center
2012
28 Citations (Scopus)

Close association between oral Candida species and oral mucosal disorders in patients with xerostomia

Shinozaki, S., Moriyama, M., Hayashida, J. N., Tanaka, A., maehara, T., Ieda, S. & Nakamura, S., Oct 2012, In : Oral Diseases. 18, 7, p. 667-672 6 p.

Research output: Contribution to journalArticle

Xerostomia
Candida
Oral Candidiasis
Oral Health
Tongue
48 Citations (Scopus)

Cytokine/chemokine profiles contribute to understanding the pathogenesis and diagnosis of primary Sjögren's syndrome

Moriyama, M., Jun-Nosuke, H., Toyoshima, T., Ohyama, Y., Shinozaki, S., Tanaka, A., maehara, T. & Nakamura, S., Jul 1 2012, In : Clinical and Experimental Immunology. 169, 1, p. 17-26 10 p.

Research output: Contribution to journalArticle

Chemokines
Cytokines
Lip
Salivary Glands
Chemokine Receptors
80 Citations (Scopus)

Interleukin-21 contributes to germinal centre formation and immunoglobulin G4 production in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease

maehara, T., Moriyama, M., Nakashima, H., Miyake, K., Jun-Nosuke, H., Tanaka, A., Shinozaki, S., Kubo, Y. & Nakamura, S., Dec 1 2012, In : Annals of the Rheumatic Diseases. 71, 12, p. 2011-2019 9 p.

Research output: Contribution to journalArticle

Mikulicz' Disease
Dacryocystitis
Sialadenitis
Germinal Center
Immunoglobulins
50 Citations (Scopus)

Selective localization of T helper subsets in labial salivary glands from primary Sjögren's syndrome patients

Maehara, T., Moriyama, M., Hayashida, J. N., Tanaka, A., Shinozaki, S., Kubo, Y., Matsumura, K. & Nakamura, S., Aug 1 2012, In : Clinical and Experimental Immunology. 169, 2, p. 89-99 11 p.

Research output: Contribution to journalArticle

Lip
Salivary Glands
Germinal Center
Real-Time Polymerase Chain Reaction
Transcription Factors
158 Citations (Scopus)

Th2 and regulatory immune reactions contribute to IgG4 production and the initiation of Mikulicz disease

Tanaka, A., Moriyama, M., Nakashima, H., Miyake, K., Jun-Nosuke, H., maehara, T., Shinozaki, S., Kubo, Y. & Nakamura, S., Jan 1 2012, In : Arthritis and rheumatism. 64, 1, p. 254-263 10 p.

Research output: Contribution to journalArticle

Mikulicz' Disease
Immunoglobulin G
Interleukin-4
Interleukin-10
Regulatory T-Lymphocytes