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Research Output 2003 2019

  • 1365 Citations
  • 18 h-Index
  • 89 Article
  • 1 Comment/debate
  • 1 Review article
2019
Balloon Angioplasty
Pulmonary Hypertension
Lung
Therapeutics
ROC Curve

Corrigendum to “Effects of menstrual cycle on background parenchymal enhancement and detectability of breast cancer on dynamic contrast-enhanced breast MRI: A multicenter study of an Asian population” [Eur. J. Radiol. 110 (2019) 130–135] (European Journal of Radiology (2019) 110 (130–135), (S0720048X18304200), (10.1016/j.ejrad.2018.11.025))

Kamitani, T., Yabuuchi, H., Kanemaki, Y., Tozaki, M., Sonomura, T., Mizukoshi, W., Nakata, W., Shimono, T., Urano, M., Yamano, T., Kato, F., Kuchiki, M., Shiraga, N., Yanagita, H., Katsuda, E., Kataoka, M., Yamaguchi, K., Horikoshi, T., Gomi, T., Nozaki, M. & 9 others, Shiotani, M., Amano, M., Saigusa, H., Sadaoka, S., Kamiya, H., Kubo, M., Yamashita, N., Yamamoto, H. & Honda, H., May 1 2019, In : European Journal of Radiology. 114, 1 p.

Research output: Contribution to journalComment/debate

Menstrual Cycle
Radiology
Multicenter Studies
Names
Breast

Effects of menstrual cycle on background parenchymal enhancement and detectability of breast cancer on dynamic contrast-enhanced breast MRI: A multicenter study of an Asian population

Kamitani, T., Yabuuchi, H., Kanemaki, Y., Tozaki, M., Sonomura, T., Mizukoshi, W., Nakata, W., Shimono, T., Urano, M., Yamano, T., Kato, F., Kuchiki, M., Shiragami, N., Yanagita, H., Katsuda, E., Kataoka, M., Yamaguchi, K., Horikoshi, T., Gomi, T., Nozaki, M. & 9 others, Shiotani, M., Amano, M., Saigusa, H., Sadaoka, S., Kamiya, H., Kubo, M., Yamashita, N., Yamamoto, H. & Honda, H., Jan 1 2019, In : European Journal of Radiology. 110, p. 130-135 6 p.

Research output: Contribution to journalArticle

Menstrual Cycle
Multicenter Studies
Follicular Phase
Breast
Breast Neoplasms
Humeral Head
Cartilage
Articular Cartilage
Magnetic Resonance Imaging
Control Groups

Feasible scan timing for 320-row coronary CT angiography generated by the time to peak in the ascending aorta

Shirasaka, T., Nagao, M., Yamasaki, Y., Kojima, T., Kondo, M., Shimomiya, Y., Kamitani, T. & Honda, H., Mar 1 2019, In : Clinical Imaging. 54, p. 153-158 6 p.

Research output: Contribution to journalArticle

Coronary Angiography
Aorta
Arteries
Heart Atria
Thoracic Aorta

Image Quality and ADC Assessment in Turbo Spin-Echo and Echo-Planar Diffusion-Weighted MR Imaging of Tumors of the Head and Neck

Panyarak, W., Chikui, T., Yamashita, Y., Kamitani, T. & Yoshiura, K., Oct 1 2019, In : Academic Radiology. 26, 10, p. e305-e316

Research output: Contribution to journalArticle

Neck
Head
Neoplasms
Echo-Planar Imaging
Signal-To-Noise Ratio
1 Citation (Scopus)

Localized malignant pleural mesothelioma mimicking an anterior mediastinal tumor

Hino, T., Kamitani, T., Sagiyama, K., Yamasaki, Y., Okamoto, I., Tagawa, T., Ijichi, K., Yamamoto, H., Yabuuchi, H. & Honda, H., Jan 1 2019, In : European Journal of Radiology Open. 6, p. 72-77 6 p.

Research output: Contribution to journalArticle

Neoplasms
Pleura
Mediastinum
Differential Diagnosis
Malignant Mesothelioma

Pulmonary metastasis presenting as a ground glass opacity-like lesion with a thin-walled cavity: A case report

Haro, A., Wakasu, S., Takada, K., Osoegawa, A., Kamitani, T., Tagawa, T. & Mori, M., Jan 1 2019, In : International Journal of Surgery Case Reports. 60, p. 287-290 4 p.

Research output: Contribution to journalArticle

Open Access
Glass
Tongue Neoplasms
Neoplasm Metastasis
Lung
Lymph Nodes

The reproducibility of measurements using a standardization phantom for the evaluation of fractional anisotropy (FA) derived from diffusion tensor imaging (DTI)

Kimura, M., Yabuuchi, H., Matsumoto, R., Kobayashi, K., Yamashita, Y., Nagatomo, K., Mikayama, R., Kamitani, T., Sagiyama, K. & Yamasaki, Y., Jan 1 2019, (Accepted/In press) In : Magnetic Resonance Materials in Physics, Biology and Medicine.

Research output: Contribution to journalArticle

2018
3 Citations (Scopus)

Clinical application of radiation dose reduction for head and neck CT

Yabuuchi, H., Kamitani, T., Sagiyama, K., Yamasaki, Y., Matsuura, Y., Hino, T., Tsutsui, S., Kondo, M., Shirasaka, T. & Honda, H., Oct 1 2018, In : European Journal of Radiology. 107, p. 209-215 7 p.

Research output: Contribution to journalReview article

Neck
Head
Radiation
Hypopharynx
Computer-Assisted Image Processing
6 Citations (Scopus)

Comparison of intravoxel incoherent motion diffusion-weighted imaging between turbo spin-echo and echo-planar imaging of the head and neck

Mikayama, R., Yabuuchi, H., Sonoda, S., Kobayashi, K., Nagatomo, K., Kimura, M., Kawanami, S., Kamitani, T., Kumazawa, S. & Honda, H., Jan 1 2018, In : European Radiology. 28, 1, p. 316-324 9 p.

Research output: Contribution to journalArticle

Echo-Planar Imaging
Neck
Head
9 Citations (Scopus)

Computed tomography features of resected lung adenocarcinomas with spread through air spaces

Toyokawa, G., Yamada, Y., Tagawa, T., Kamitani, T., Yamasaki, Y., Shimokawa, M., Oda, Y. & Maehara, Y., Oct 1 2018, In : Journal of Thoracic and Cardiovascular Surgery. 156, 4, p. 1670-1676.e4

Research output: Contribution to journalArticle

Air
Tomography
Glass
Adenocarcinoma
Adenocarcinoma of lung

Free-breathing 320-row computed tomographic angiography with low-tube voltage and hybrid iterative reconstruction in infants with complex congenital heart disease

Yamasaki, Y., Kawanami, S., Kamitani, T., Sagiyama, K., Shin, S., Hino, T., Yamamura, K., Yabuuchi, H., Nagao, M. & Honda, H., Jul 1 2018, In : Clinical Imaging. 50, p. 147-156 10 p.

Research output: Contribution to journalArticle

Heart Diseases
Angiography
Electrocardiography
Respiration
Computed Tomography Angiography
3 Citations (Scopus)
Breath Holding
Oximetry
Atrial Heart Septal Defects
Respiration
Magnetic Resonance Imaging
1 Citation (Scopus)
Heart Diseases
Coronary Vessels
Angiography
Aorta
Electrocardiography
1 Citation (Scopus)
Therapeutic Uses
Platinum
Non-Small Cell Lung Carcinoma
Perfusion
Tomography
2017
19 Citations (Scopus)
Balloon Angioplasty
Pulmonary Hypertension
Stroke Volume
Lung
Magnetic Resonance Imaging
1 Citation (Scopus)

Detectability of BI-RADS category 3 or higher breast lesions and reading time on mammography: Comparison between 5-MP and 8-MP LCD monitors

Yabuuchi, H., Kawanami, S., Kamitani, T., Matsumura, T., Yamasaki, Y., Morishita, J. & Honda, H., Apr 1 2017, In : Acta Radiologica. 58, 4, p. 403-407 5 p.

Research output: Contribution to journalArticle

Liquid Crystals
Mammography
Information Systems
Reading
Breast
3 Citations (Scopus)
Balloon Angioplasty
Pulmonary Hypertension
Pulmonary Artery
Lung
Magnetic Resonance Imaging
2 Citations (Scopus)

Geometrical characteristics of aortic root and left ventricular dysfunction in aortic stenosis: quantification of 256-slice coronary CT angiography

Nagao, M., Yamasaki, Y., Kamitani, T., Kawanami, S., Kondo, M., Sonoda, H., Fujioka, T. & Honda, H., May 1 2017, In : Heart and Vessels. 32, 5, p. 558-565 8 p.

Research output: Contribution to journalArticle

Aortic Valve Stenosis
Left Ventricular Dysfunction
Coronary Angiography
ROC Curve
Left Ventricular Function
4 Citations (Scopus)

One-stop shop assessment for atrial septal defect closure using 256-slice coronary CT angiography

Yamasaki, Y., Nagao, M., Kawanami, S., Kamitani, T., Sagiyama, K., Yamanouchi, T., Sakamoto, I., Yamamura, K., Yabuuchi, H. & Honda, H., Feb 1 2017, In : European Radiology. 27, 2, p. 697-704 8 p.

Research output: Contribution to journalArticle

Atrial Heart Septal Defects
Transesophageal Echocardiography
Coronary Angiography
Cardiac Catheterization
Computer-Assisted Image Processing
3 Citations (Scopus)

Quantification of myocardial oxygenation in heart failure using blood-oxygen-level-dependent T2* magnetic resonance imaging: Comparison with cardiopulmonary exercise test

Nagao, M., Yamasaki, Y., Kawanami, S., Kamitani, T., Sagiyama, K., Higo, T., Ide, T., Takemura, A., Ishizaki, U., Fukushima, K., Watanabe, Y. & Honda, H., Jun 1 2017, In : Magnetic Resonance Imaging. 39, p. 138-143 6 p.

Research output: Contribution to journalArticle

Oxygenation
Magnetic resonance
Exercise Test
Blood
Heart Failure
12 Citations (Scopus)

Relevance Between Programmed Death Ligand 1 and Radiologic Invasiveness in Pathologic Stage I Lung Adenocarcinoma

Toyokawa, G., Takada, K., Okamoto, T., Kawanami, S., Kozuma, Y., Matsubara, T., Haratake, N., Takamori, S., Akamine, T., Katsura, M., Yamada, Y., Shoji, F., Baba, S., Kamitani, T., Oda, Y., Honda, H. & Maehara, Y., Jun 1 2017, In : Annals of Thoracic Surgery. 103, 6, p. 1750-1757 8 p.

Research output: Contribution to journalArticle

Ligands
Adenocarcinoma
Adenocarcinoma of lung
Neoplasms
Immunotherapy
2016
6 Citations (Scopus)

Clinical impact of left ventricular eccentricity index using cardiac MRI in assessment of right ventricular hemodynamics and myocardial fibrosis in congenital heart disease

Yamasaki, Y., Nagao, M., Kamitani, T., Yamanouchi, T., Kawanami, S., Yamamura, K., Sakamoto, I., Yabuuchi, H. & Honda, H., Oct 1 2016, In : European Radiology. 26, 10, p. 3617-3625 9 p.

Research output: Contribution to journalArticle

Heart Diseases
Fibrosis
Hemodynamics
Gadolinium
Cine Magnetic Resonance Imaging

Feeding Arteries of Primary Tongue Cancers on Intra-arterial Infusion Chemotherapy

Kamitani, T., Kawanami, S., Asayama, Y., Matsuo, Y., Yonezawa, M., Yamasaki, Y., Nagao, M., Yamanouchi, T., Yabuuchi, H., Nakamura, K., Nakashima, T. & Honda, H., Feb 1 2016, In : CardioVascular and Interventional Radiology. 39, 2, p. 227-232 6 p.

Research output: Contribution to journalArticle

Tongue Neoplasms
Intra Arterial Infusions
Arteries
Drug Therapy
Tongue
1 Citation (Scopus)

Lymphomatoid granulomatosis

Yamanouchi, T., Kawanami, S., Kamitani, T., Sagiyama, K., Yamasaki, Y., Tanaka, Y., Nagao, M., Yabuuchi, H., Hamada, N., Okamoto, T., Yamamoto, H. & Honda, H., Nov 1 2016, In : Journal of Thoracic Imaging. 31, 6, p. W80-W82

Research output: Contribution to journalArticle

4 Citations (Scopus)

Prediction of post-operative pulmonary function after lobectomy for primary lung cancer: A comparison among counting method, effective lobar volume, and lobar collapsibility using inspiratory/expiratory CT

Yabuuchi, H., Kawanami, S., Kamitani, T., Yonezawa, M., Yamasaki, Y., Yamanouchi, T., Nagao, M., Okamoto, T. & Honda, H., Nov 1 2016, In : European Journal of Radiology. 85, 11, p. 1956-1962 7 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Respiratory Function Tests
Lung
2 Citations (Scopus)

Quantification of coronary flow using dynamic angiography with 320-detector row CT and motion coherence image processing: Detection of ischemia for intermediate coronary stenosis

Nagao, M., Yamasaki, Y., Kamitani, T., Kawanami, S., Sagiyama, K., Yamanouchi, T., Shimomiya, Y., Matoba, T., Mukai, Y., Odashiro, K., Baba, S., Maruoka, Y., Kitamura, Y., Nishie, A. & Honda, H., May 1 2016, In : European Journal of Radiology. 85, 5, p. 996-1003 8 p.

Research output: Contribution to journalArticle

Coronary Stenosis
Angiography
Ischemia
Coronary Vessels
Myocardial Perfusion Imaging
2015
12 Citations (Scopus)

Anterior mediastinal solid tumours in adults: Characterisation using dynamic contrast-enhanced MRI, diffusion-weighted MRI, and FDG-PET/CT

Yabuuchi, H., Matsuo, Y., Abe, K., Baba, S., Sunami, S., Kamitani, T., Yonezawa, M., Yamasaki, Y., Kawanami, S., Nagao, M., Okamoto, T., Nakamura, K., Yamamoto, H., Sasaki, M. & Honda, H., Nov 1 2015, In : Clinical Radiology. 70, 11, p. 1289-1298 10 p.

Research output: Contribution to journalArticle

Diffusion Magnetic Resonance Imaging
Glucose
Thymoma
Validation Studies
Germ Cell and Embryonal Neoplasms

Atypical CT findings of metastatic lung tumor

Kamitani, T., Yonezawa, M., Yamasaki, Y., Fujita, Y., Honda, H., Matsuo, Y., kubo, Y., Kawanami, S., Nagao, M. & Yabuuchi, H., Jan 1 2015, In : Japanese Journal of Clinical Radiology. 60, 1, p. 81-88 8 p.

Research output: Contribution to journalArticle

Lung
Neoplasms
3 Citations (Scopus)
Liquid Crystals
Lung Neoplasms
Thorax
Area Under Curve
X Ray Computed Tomography
7 Citations (Scopus)
Extracellular Space
Squamous Cell Carcinoma
Plasma Volume
Neoplasm Metastasis
Neoplasms
20 Citations (Scopus)

Impact of interstitial changes on radiation pneumonitis after stereotactic body radiation therapy for lung cancer

Yoshitake, T., Shioyama, Y., Asai, K., Nakamura, K., Sasaki, T., Saiji, O., Kamitani, T., Yamaguchi, T., Ohshima, K., Matsumoto, K., Kawanami, S. & Honda, H., Jan 1 2015, In : Anticancer Research. 35, 9, p. 4909-4914 6 p.

Research output: Contribution to journalArticle

Radiation Pneumonitis
Lung Neoplasms
Radiotherapy
Multivariate Analysis
Tomography
10 Citations (Scopus)

Interventricular Dyssynchrony Using Tagging Magnetic Resonance Imaging Predicts Right Ventricular Dysfunction in Adult Congenital Heart Disease

Nagao, M., Yamasaki, Y., Yonezawa, M., Matsuo, Y., Kamitani, T., Yamamura, K., Sakamoto, I., Abe, K., Kawanami, S. & Honda, H., May 1 2015, In : Congenital Heart Disease. 10, 3, p. 271-280 10 p.

Research output: Contribution to journalArticle

Right Ventricular Dysfunction
Patient Rights
Heart Diseases
Magnetic Resonance Imaging
Ventricular Pressure
2 Citations (Scopus)

Low-dose CT screening using hybrid iterative reconstruction: Confidence ratings of diagnoses of simulated lesions other than lung cancer

Sakai, N., Yabuuchi, H., Kondo, M., Matsuo, Y., Kamitani, T., Nagao, M., Jinnouchi, M., Yonezawa, M., Kojima, T., Yano, Y. & Honda, H., Sep 1 2015, In : British Journal of Radiology. 88, 1053, 20150159.

Research output: Contribution to journalArticle

Lung Neoplasms
Noise
Thorax
Mediastinal Emphysema
Cone-Beam Computed Tomography
6 Citations (Scopus)

Mediastinal paraganglioma

Takashima, Y., Kamitani, T., Kawanami, S., Nagao, M., Yonezawa, M., Yamasaki, Y., Baba, S., Yabuuchi, H., Hida, T., Kouhashi, K., Nakamura, K., Sonoda, H., Oda, Y. & Honda, H., Jul 25 2015, In : Japanese Journal of Radiology. 33, 7, p. 433-436 4 p.

Research output: Contribution to journalArticle

Paraganglioma
3-Iodobenzylguanidine
Neoplasms
Fluorodeoxyglucose F18
Radionuclide Imaging

Myocardial strain analysis by cardiac MRI and CT: Clinical implication

Nagao, M., Kawanami, S., Yonezawa, M., Yamasaki, Y., Kamitani, T., Fujita, Y., Yamanouchi, T., Honda, H. & Nagao, M., Jan 1 2015, In : Japanese Journal of Clinical Radiology. 60, 2, p. 230-237 8 p.

Research output: Contribution to journalArticle

Heart Ventricles
Cine Magnetic Resonance Imaging
Right Ventricular Dysfunction
Myocardial Contraction
Aortic Diseases
7 Citations (Scopus)

Prediction of adverse cardiac events in dilated cardiomyopathy using cardiac T2* MRI and MIBG scintigraphy

Nagao, M., Baba, S., Yonezawa, M., Yamasaki, Y., Kamitani, T., Isoda, T., Kawanami, S., Maruoka, Y., Kitamura, Y., Abe, K., Higo, T., Sunagawa, K. & Honda, H., Feb 27 2015, In : International Journal of Cardiovascular Imaging. 31, 2, p. 399-407 9 p.

Research output: Contribution to journalArticle

Dilated Cardiomyopathy
Radionuclide Imaging
Iron
Ventricular Septum
ROC Curve
7 Citations (Scopus)

Volumetric measurement of artificial pure ground-glass nodules at low-dose CT: Comparisons between hybrid iterative reconstruction and filtered back projection

Sakai, N., Yabuuchi, H., Kondo, M., Kojima, T., Nagatomo, K., Kawanami, S., Kamitani, T., Yonezawa, M., Nagao, M. & Honda, H., Jan 1 2015, In : European Journal of Radiology. 84, 12, p. 2654-2662 9 p.

Research output: Contribution to journalArticle

Glass
Tomography
Observer Variation
Lung
Thorax
2014
19 Citations (Scopus)

Apparent diffusion coefficient is a prognostic factor of head and neck squamous cell carcinoma treated with radiotherapy

Hatakenaka, M., Nakamura, K., Yabuuchi, H., Shioyama, Y., Matsuo, Y., Kamitani, T., Yonezawa, M., Yoshiura, T., Nakashima, T., Mori, M. & Honda, H., Feb 1 2014, In : Japanese Journal of Radiology. 32, 2, p. 80-89 10 p.

Research output: Contribution to journalArticle

Radiotherapy
Disease-Free Survival
Survival
Hypopharynx
Oropharynx
1 Citation (Scopus)
Interstitial Lung Diseases
Radiography
Thorax
Lung
Area Under Curve

Diagnosis of minor, accessory and heterotopic salivary gland tumors

Sunami, S., Matsuo, Y., Kamitani, T., Honda, H. & Torii, Y., Jan 1 2014, In : Japanese Journal of Clinical Radiology. 59, 5, p. 642-656 15 p.

Research output: Contribution to journalArticle

Glandular and Epithelial Neoplasms
Salivary Glands
Neck
Head
Neoplasms
13 Citations (Scopus)

Differentiation between benign phyllodes tumors and fibroadenomas of the breast on MR imaging

Kamitani, T., Matsuo, Y., Yabuuchi, H., fujita, N., Nagao, M., Kawanami, S., Yonezawa, M., Yamasaki, Y., Tokunaga, E., Kubo, M., Yamamoto, H. & Honda, H., Jan 1 2014, In : European Journal of Radiology. 83, 8, p. 1344-1349 6 p.

Research output: Contribution to journalArticle

Phyllodes Tumor
Fibroadenoma
Breast
Internal Capsule
Retrospective Studies
13 Citations (Scopus)
Systemic Scleroderma
Interstitial Lung Diseases
Glass
Peripheral Blood Stem Cell Transplantation
Vital Capacity

Fusion of cardiac nuclear medicine and MRI: New insight in cardiomyopathy

Nagao, M., Kawanami, S., Baba, S., Yonezawa, M., Yamasaki, Y., Kamitani, T., Isoda, T., Maruoka, Y., Kitamura, N. & Honda, H., 2014, In : Japanese Journal of Clinical Radiology. 59, 13, p. 1812-1820 9 p.

Research output: Contribution to journalArticle

Nuclear Medicine
Dilated Cardiomyopathy
Cardiomyopathies
Sarcoidosis
3-Iodobenzylguanidine
7 Citations (Scopus)

Geometrical characteristics of left ventricular dyssynchrony in advanced heart failure: Myocardial strain analysis by tagged MRI

Nagao, M., Yamasaki, Y., Yonezawa, M., Kamitani, T., Kawanami, S., Mukai, Y., Higo, T., Yabuuchi, H., Sunagawa, K. & Honda, H., Jan 1 2014, In : International heart journal. 55, 6, p. 512-518 7 p.

Research output: Contribution to journalArticle

Heart Failure
Cine Magnetic Resonance Imaging
Logistic Models
Regression Analysis
Blood Pressure
14 Citations (Scopus)

Quantification of myocardial iron deficiency in nonischemic heart failure by cardiac T2* magnetic resonance imaging

Nagao, M., Matsuo, Y., Kamitani, T., Yonezawa, M., Yamasaki, Y., Kawanami, S., Abe, K., Mukai, Y., Higo, T., Yabuuchi, H., Takemura, A., Yoshiura, T., Sunagawa, K. & Honda, H., Mar 15 2014, In : American Journal of Cardiology. 113, 6, p. 1024-1030 7 p.

Research output: Contribution to journalArticle

Iron
Heart Failure
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Biomarkers
20 Citations (Scopus)

Quantitative assessment of right ventricular function and pulmonary regurgitation in surgically repaired tetralogy of Fallot using 256-slice CT: comparison with 3-Tesla MRI

Yamasaki, Y., Nagao, M., Yamamura, K., Yonezawa, M., Matsuo, Y., Kawanami, S., Kamitani, T., Higuchi, K., Sakamoto, I., Shiokawa, Y., Yabuuchi, H. & Honda, H., Nov 14 2014, In : European Radiology. 24, 12, p. 3289-3299 11 p.

Research output: Contribution to journalArticle

Pulmonary Valve Insufficiency
Right Ventricular Function
Tetralogy of Fallot
Tomography
Magnetic Resonance Spectroscopy
2013
40 Citations (Scopus)

Correlations between apparent diffusion coefficient values and prognostic factors of breast cancer

Kamitani, T., Matsuo, Y., Yabuuchi, H., fujita, N., Nagao, M., Jinnouchi, M., Yonezawa, M., Yamasaki, Y., Tokunaga, E., Kubo, M., Yamamoto, H., Yoshiura, T. & Honda, H., Oct 7 2013, In : Magnetic Resonance in Medical Sciences. 12, 3, p. 193-199 7 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Estrogen Receptors
Neoplasms
Progesterone Receptors
Ductal Carcinoma
3 Citations (Scopus)

Detectability of simulated pulmonary nodules on chest radiographs: Comparison between irradiation side sampling indirect flat-panel detector and computed radiography

Yano, Y., Yabuuchi, H., Tanaka, N., Morishita, J., Tsutomu, A., Matsuo, Y., Sunami, S., Kamitani, T., Jinnouchi, M., Yamasaki, Y., Nagao, M. & Sasaki, M., Nov 1 2013, In : European Journal of Radiology. 82, 11, p. 2050-2054 5 p.

Research output: Contribution to journalArticle

Radiography
Thorax
Lung
ROC Curve
Liquid Crystals