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Research Output 1989 2019

  • 3433 Citations
  • 34 h-Index
  • 123 Article
  • 2 Review article
  • 1 Book
  • 1 Letter
2019
1 Citation (Scopus)
Glycosylation
Stereoselectivity
Oligosaccharides
linkages
reactivity
1 Citation (Scopus)

Design and synthesis of artificial ladder-shaped polyethers for exploring biological functions

Oishi, T., Jan 1 2019, In : Heterocycles. 99, 1, p. 21-53 33 p.

Research output: Contribution to journalArticle

Dinoflagellida
Polyethers
Ladders
Molecular Structure
Biological Products

Simple Apparatus for Adding Small Amounts of Powder Materials under an Inert Atmosphere

Karak, M., Joh, Y., Khodjaniyazov, K. U., Sagdullaev, S. S., Oishi, T. & Torikai, K., Jan 1 2019, In : Synlett. 30, 18, p. 2058-2061 4 p.

Research output: Contribution to journalArticle

Powders
Glycosylation
Syringes
Contamination
Moisture

Unified synthesis of the DEF and GhI ring systems of maitotoxin

Yasudomi, T., Yakushiji, H., Torikai, K., Ebine, M. & Oishi, T., Jan 1 2019, In : Chemistry Letters. 48, 9, p. 1156-1159 4 p.

Research output: Contribution to journalArticle

Acetals
Methylation
Ethers
Alkenes
Derivatives
2018
Amphotericin B
Nuclear magnetic resonance
Anti-Bacterial Agents
Membranes
Ergosterol
4 Citations (Scopus)

Convergent syntheses of the WXYZ ring of maitotoxin and the HIJK ring of brevisulcenal-F

Osato, N., Onoue, H., Toma, Y., Torikai, K., Ebine, M., Satake, M. & Oishi, T., Jan 1 2018, In : Chemistry Letters. 47, 3, p. 265-268 4 p.

Research output: Contribution to journalArticle

Ketones
Stereochemistry
Methylation
Lithium
Aldehydes
1 Citation (Scopus)

Flow synthesis of (3R)- and (3S)-(E)-1-iodohexa-1,5-dien-3-ol: Chiral building blocks for natural product synthesis

Katayama, S., Koge, T., Katsuragi, S., Akai, S. & Oishi, T., Jan 1 2018, In : Chemistry Letters. 47, 9, p. 1116-1118 3 p.

Research output: Contribution to journalArticle

Ion Exchange Resins
Biological Products
Lipase
Evaporation
Acetates
1 Citation (Scopus)

Synthesis and complete structure determination of a sperm-activating and -attracting factor isolated from the ascidian ascidia sydneiensis

Watanabe, T., Shibata, H., Ebine, M., Tsuchikawa, H., Matsumori, N., Murata, M., Yoshida, M., Morisawa, M., Lin, S., Yamauchi, K., Sakai, K. & Oishi, T., Apr 27 2018, In : Journal of Natural Products. 81, 4, p. 985-997 13 p.

Research output: Contribution to journalArticle

Ergosterol
Urochordata
Biological Products
Ketones
Eggs
3 Citations (Scopus)

Synthesis and Stereochemical Revision of the C31–C67 Fragment of Amphidinol 3

Wakamiya, Y., Ebine, M., Murayama, M., Omizu, H., Matsumori, N., Murata, M. & Oishi, T., May 22 2018, In : Angewandte Chemie - International Edition. 57, 21, p. 6060-6064 5 p.

Research output: Contribution to journalArticle

Degradation
Biological Products
Carbon
Nuclear magnetic resonance
Availability
1 Citation (Scopus)

Synthesis of 6/6/6-tricyclic ether system via Achmatowicz and intramolecular oxa-michael reactions

Yamamoto, H., Torikai, K., Ebine, M. & Oishi, T., Jan 1 2018, In : Heterocycles. 97, 1, p. 158-162 5 p.

Research output: Contribution to journalArticle

Ethers
Aldehydes
Isomers
Ether
Alcohols

Synthesis of an analog of amphidinol 3 corresponding to the c31-c67 section

Koge, T., Wakamiya, Y., Ebine, M. & Oishi, T., Jan 1 2018, In : Heterocycles. 96, 7, p. 1197-1202 6 p.

Research output: Contribution to journalArticle

Structure-Activity Relationship
Derivatives
amphidinol 3
polyol
2 Citations (Scopus)

Synthesis of anti-tubercular marine alkaloids denigrins A and B

Karak, M., Oishi, T. & Torikai, K., Jul 18 2018, In : Tetrahedron Letters. 59, 29, p. 2800-2803 4 p.

Research output: Contribution to journalArticle

Maleic Anhydrides
Alkaloids
Cross Reactions
Palladium
Salts
2017
1 Citation (Scopus)

1-Naphthylmethyl and 1-naphthylmethoxymethyl protecting groups: New members of the benzyl- and benzyloxymethyl-type family

Sato, T., Joh, Y., Oishi, T. & Torikai, K., Jan 1 2017, In : Tetrahedron Letters. 58, 23, p. 2178-2181 4 p.

Research output: Contribution to journalArticle

Oxidation
Hydrogenolysis
Nucleophiles
Temperature
Acids
5 Citations (Scopus)

Design and synthesis of benzoacridines as estrogenic and anti-estrogenic agents

Torikai, K., Koga, R., Liu, X., Umehara, K., Kitano, T., Watanabe, K., Oishi, T., Noguchi, H. & Shimohigashi, Y., Jan 1 2017, In : Bioorganic and Medicinal Chemistry. 25, 20, p. 5216-5237 22 p.

Research output: Contribution to journalArticle

Estrogens
Estrogen Receptors
Orphan Nuclear Receptors
Selective Estrogen Receptor Modulators
Inhibitory Concentration 50
3 Citations (Scopus)

Syntheses and Biological Activities of the LMNO, ent-LMNO, and NOPQR(S) Ring Systems of Maitotoxin

Onoue, H., Marubayashi, R., Ishikawa, E., Konoki, K., Torikai, K., Ebine, M., Murata, M. & Oishi, T., Jan 1 2017, In : Journal of Organic Chemistry. 82, 18, p. 9595-9618 24 p.

Research output: Contribution to journalArticle

Bioactivity
Enantiomers
Aldehydes
Alkynes
Biological Products
3 Citations (Scopus)

Synthesis of a truncated analog of amphidinol 3 corresponding to the C21C39/C52C67 section

Ebine, M., Takada, Y., Yanai, N. & Oishi, T., Jan 1 2017, In : Chemistry Letters. 46, 5, p. 662-664 3 p.

Research output: Contribution to journalArticle

Polyenes
amphidinol 3
2016
12 Citations (Scopus)

The Structure of the Bimolecular Complex between Amphotericin B and Ergosterol in Membranes Is Stabilized by Face-to-Face van der Waals Interaction with Their Rigid Cyclic Cores

Nakagawa, Y., Umegawa, Y., Matsushita, N., Yamamoto, T., Tsuchikawa, H., Hanashima, S., Oishi, T., Matsumori, N. & Murata, M., Jun 21 2016, In : Biochemistry. 55, 24, p. 3392-3402 11 p.

Research output: Contribution to journalArticle

Ergosterol
Amphotericin B
Membranes
Macrolides
Polyenes
2015
2 Citations (Scopus)

2-Naphthylmethoxymethyl as a Mildly Introducible and Oxidatively Removable Benzyloxymethyl-Type Protecting Group

Sato, T., Oishi, T. & Torikai, K., Jun 19 2015, In : Organic Letters. 17, 12, p. 3110-3113 4 p.

Research output: Contribution to journalArticle

Chlorides
Temperature
compatibility
chlorides
2,6-lutidine
10 Citations (Scopus)

Axial hydrogen at C7 position and bumpy tetracyclic core markedly reduce sterol's affinity to amphotericin B in membrane

Nakagawa, Y., Umegawa, Y., Nonomura, K., Matsushita, N., Takano, T., Tsuchikawa, H., Hanashima, S., Oishi, T., Matsumori, N. & Murata, M., Jan 20 2015, In : Biochemistry. 54, 2, p. 303-312 10 p.

Research output: Contribution to journalArticle

Amphotericin B
Sterols
Hydrogen
Membranes
Macrolides
15 Citations (Scopus)

Stereoselective synthesis of the C1-C29 part of amphidinol 3

Tsuruda, T., Ebine, M., Umeda, A. & Oishi, T., Jan 16 2015, In : Journal of Organic Chemistry. 80, 2, p. 859-871 13 p.

Research output: Contribution to journalArticle

Lithium
Amides
amphidinol 3
1 Citation (Scopus)

Tuned Classical Thermal Aromatization Furnishing an Estrogenic Benzoacridine

Koga, R., Oishi, T. & Torikai, K., Dec 17 2015, In : Synlett. 26, 20, p. 2801-2805 5 p., st-2015-s0585-c.

Research output: Contribution to journalArticle

Aromatization
Estrogens
Derivatives
Pharmaceutical Preparations
Hot Temperature
2014
11 Citations (Scopus)

Synthesis and biological activity of the C'D'E'F' ring system of maitotoxin

Kunitake, M., Oshima, T., Konoki, K., Ebine, M., Torikai, K., Murata, M. & Oishi, T., Jun 6 2014, In : Journal of Organic Chemistry. 79, 11, p. 4948-4962 15 p.

Research output: Contribution to journalArticle

Cyclization
Bioactivity
Rats
maitotoxin
allyl alcohol
8 Citations (Scopus)

Synthesis and biological activity of the QRS ring system of maitotoxin

Onoue, H., Baba, T., Konoki, K., Torikai, K., Ebine, M. & Oishi, T., Jan 1 2014, In : Chemistry Letters. 43, 12, p. 1904-1906 3 p.

Research output: Contribution to journalArticle

Bioactivity
Acetals
Methylation
Polyethers
Ladders
2013
8 Citations (Scopus)

A novel sperm-activating and attracting factor from the ascidian Ascidia sydneiensis

Matsumori, N., Hiradate, Y., Shibata, H., Oishi, T., Shimma, S., Toyoda, M., Hayashi, F., Yoshida, M., Murata, M. & Morisawa, M., Jan 18 2013, In : Organic Letters. 15, 2, p. 294-297 4 p.

Research output: Contribution to journalArticle

tactics
Urochordata
Chemotaxis
Biological Products
Spermatozoa
3 Citations (Scopus)

Guest responsivity of a two-dimensional coordination polymer incorporating a cholesterol-based co-ligand

Kajitani, K., Koshiyama, T., Hori, A., Ohtani, R., Mishima, A., Torikai, K., Ebine, M., Oishi, T., Takata, M., Kitagawa, S. & Ohba, M., Dec 7 2013, In : Dalton Transactions. 42, 45, p. 15893-15897 5 p.

Research output: Contribution to journalArticle

Polymers
Cholesterol
Ligands
17 Citations (Scopus)

Synthesis and structure revision of the C43-C67 part of amphidinol 3

Ebine, M., Kanemoto, M., Manabe, Y., Konno, Y., Sakai, K., Matsumori, N., Murata, M. & Oishi, T., Jun 26 2013, In : Organic Letters. 15, 11, p. 2846-2849 4 p.

Research output: Contribution to journalArticle

nuclear magnetic resonance
oxidation
synthesis
configurations
Nuclear magnetic resonance
2012
7 Citations (Scopus)

Artificial ladder-shaped polyethers that inhibit maitotoxin-induced Ca 2+ influx in rat glioma C6 cells

Oishi, T., Konoki, K., Tamate, R., Torikai, K., Hasegawa, F., Matsumori, N. & Murata, M., Jun 1 2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 11, p. 3619-3622 4 p.

Research output: Contribution to journalArticle

Dinoflagellida
Polyethers
Ladders
Glioma
Rats
38 Citations (Scopus)

Comprehensive molecular motion capture for sphingomyelin by site-specific deuterium labeling

Matsumori, N., Yasuda, T., Okazaki, H., Suzuki, T., Yamaguchi, T., Tsuchikawa, H., Doi, M., Oishi, T. & Murata, M., Oct 23 2012, In : Biochemistry. 51, 42, p. 8363-8370 8 p.

Research output: Contribution to journalArticle

Sphingomyelins
Deuterium
Labeling
Cholesterol
Sphingosine
14 Citations (Scopus)

Confirmation of the absolute configuration at C45 of amphidinol 3

Manabe, Y., Ebine, M., Matsumori, N., Murata, M. & Oishi, T., Dec 3 2012, In : Journal of Natural Products. 75, 11, p. 2003-2006 4 p.

Research output: Contribution to journalArticle

Dinoflagellida
Biological Products
Degradation
Esters
Carbon
3 Citations (Scopus)
Ethers
Polyethers
Ladders
Ether
Cyclic Ethers
25 Citations (Scopus)

Head-to-tail interaction between amphotericin b and ergosterol occurs in hydrated phospholipid membrane

Umegawa, Y., Nakagawa, Y., Tahara, K., Tsuchikawa, H., Matsumori, N., Oishi, T. & Murata, M., Jan 10 2012, In : Biochemistry. 51, 1, p. 83-89 7 p.

Research output: Contribution to journalArticle

Ergosterol
Amphotericin B
Phospholipids
Head
Membranes
29 Citations (Scopus)

NMR-based conformational analysis of sphingomyelin in bicelles

Yamaguchi, T., Suzuki, T., Yasuda, T., Oishi, T., Matsumori, N. & Murata, M., Jan 1 2012, In : Bioorganic and Medicinal Chemistry. 20, 1, p. 270-278 9 p.

Research output: Contribution to journalArticle

Sphingomyelins
Nuclear magnetic resonance
Conformations
Lipid bilayers
Membranes
2011
4 Citations (Scopus)

Conformations of spermine in adenosine triphosphate complex: The structural basis for weak bimolecular interactions of major cellular electrolytes

Maruyoshi, K., Yamaguchi, T., Demura, T., Matsumori, N., Oishi, T. & Murata, M., Apr 18 2011, In : Chemistry - A European Journal. 17, 17, p. 4788-4795 8 p.

Research output: Contribution to journalArticle

Spermine
Electrolytes
Nuclear magnetic resonance spectroscopy
Conformations
Phosphates
6 Citations (Scopus)

Design and synthesis of sphingomyelin-cholesterol conjugates and their formation of ordered membranes

Matsumori, N., Tanada, N., Nozu, K., Okazaki, H., Oishi, T. & Murata, M., Jul 25 2011, In : Chemistry - A European Journal. 17, 31, p. 8568-8575 8 p.

Research output: Contribution to journalArticle

Sphingomyelins
Cholesterol
Membranes
Lipids
Molecular recognition
5 Citations (Scopus)

Synthesis of 6-F-ergosterol and its influence on membrane-permeabilization of amphotericin B and amphidinol 3

Kasai, Y., Matsumori, N., Ueno, H., Nonomura, K., Yano, S., Michio, M. & Oishi, T., Mar 1 2011, In : Organic and Biomolecular Chemistry. 9, 5, p. 1437-1442 6 p.

Research output: Contribution to journalArticle

Amphotericin B
Ergosterol
membranes
Membranes
Sterols
2010
10 Citations (Scopus)

Detection of Rap1A as a yessotoxin binding protein from blood cell membranes

Ujihara, S., Oishi, T., Mouri, R., Tamate, R., Konoki, K., Matsumori, N., Murata, M., Oshima, Y., Sugiyama, N., Tomita, M. & Ishihama, Y., Nov 15 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 22, p. 6443-6446 4 p.

Research output: Contribution to journalArticle

Cell membranes
Blood Cells
Carrier Proteins
Blood
Polyethers
16 Citations (Scopus)

Reductive etherification under microfluidic conditions: Application to practical synthesis of the FGHIJ-ring system of yessotoxin

Oishi, T., Imaizumi, T. & Murata, M., 2010, In : Chemistry Letters. 39, 2, p. 108-109 2 p.

Research output: Contribution to journalArticle

Microfluidics
yessotoxin
2 Citations (Scopus)

Second-generation synthesis of endogenous sperm-activating and attracting factor (SAAF) isolated from the ascidian Ciona intestinalis

Oishi, T., Ootou, K., Shibata, H. & Murata, M., May 12 2010, In : Tetrahedron Letters. 51, 19, p. 2600-2602 3 p.

Research output: Contribution to journalArticle

Ciona intestinalis
Urochordata
Spermatozoa
Molecular Probes
Epoxy Compounds
17 Citations (Scopus)

Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance

Swasono, R. T., Mouri, R., Morsy, N., Matsumori, N., Oishi, T. & Murata, M., Apr 1 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 7, p. 2215-2218 4 p.

Research output: Contribution to journalArticle

Surface Plasmon Resonance
Surface plasmon resonance
Sterols
Membranes
Ergosterol
10 Citations (Scopus)

Structural reevaluations of amphidinol 3, a potent antifungal compound from dinoflagellate

Swasono, R. T., Kanemoto, M., Matsumori, N., Oishi, T. & Murata, M., Feb 28 2010, In : Heterocycles. 82, 2, p. 1359-1369 11 p.

Research output: Contribution to journalArticle

Dinoflagellida
Organic solvents
Nuclear magnetic resonance
Membranes
amphidinol 3
2009
7 Citations (Scopus)

Conformational change of spermidine upon interaction with adenosine triphosphate in aqueous solution

Maruyoshi, K., Nonaka, K., Sagane, T., Demura, T., Yamaguchi, T., Matsumori, N., Oishi, T. & Murata, M., Feb 2 2009, In : Chemistry - A European Journal. 15, 7, p. 1618-1626 9 p.

Research output: Contribution to journalArticle

Spermidine
Conformations
Adenosine Triphosphate
Polyamines
Phospholipids
26 Citations (Scopus)

Design, synthesis, and biological evaluation of fluorinated analogues of salicylihalamide

Sugimoto, Y., Konoki, K., Murata, M., Matsushita, M., Kanazawa, H. & Oishi, T., Feb 12 2009, In : Journal of Medicinal Chemistry. 52, 3, p. 798-806 9 p.

Research output: Contribution to journalArticle

Vacuolar Proton-Translocating ATPases
Fluorine
Molecular Probes
Tumor Cell Line
Biological Products
3 Citations (Scopus)
Polyethers
Ladders
Ethers
Proteins
Molecular Probes
50 Citations (Scopus)

Direct interaction between amphotericin B and ergosterol in lipid bilayers as revealed by 2H NMR spectroscopy

Matsumori, N., Tahara, K., Yamamoto, H., Morooka, A., Doi, M., Oishi, T. & Murata, M., Aug 26 2009, In : Journal of the American Chemical Society. 131, 33, p. 11855-11860 6 p.

Research output: Contribution to journalArticle

Ergosterol
Lipid bilayers
Cholesterol
Lipid Bilayers
Amphotericin B
13 Citations (Scopus)

Ion channel complex of antibiotics as viewed by NMR

Murata, M., Kasai, Y., Umegawa, Y., Matsushita, N., Tsuchikawa, H., Matsumori, N. & Oishi, T., Jul 24 2009, In : Pure and Applied Chemistry. 81, 6, p. 1123-1129 7 p.

Research output: Contribution to journalArticle

Amphotericin B
Antibiotics
Ion Channels
Nuclear magnetic resonance
Ergosterol
8 Citations (Scopus)

Maitotoxin-photoactive probe binds to membrane proteins in blood cells

Konoki, K., Hashimoto, M., Honda, K., Tachibana, K., Tamate, R., Hasegawa, F., Oishi, T. & Murata, M., Jul 29 2009, In : Heterocycles. 79, C, p. 1007-1017 11 p.

Research output: Contribution to journalArticle

Blood Cells
Membrane Proteins
Blood
Cells
Ligands
22 Citations (Scopus)

Stereoselective synthesis of the C31-C40/C43-C52 unit of amphidinol 3

Kanemoto, M., Murata, M. & Oishi, T., Nov 20 2009, In : Journal of Organic Chemistry. 74, 22, p. 8810-8813 4 p.

Research output: Contribution to journalArticle

Alkenes
Epoxidation
Cyclization
amphidinol 3
10 Citations (Scopus)

Surface plasmon resonance-based detection of ladder-shaped polyethers by inhibition detection method

Mouri, R., Oishi, T., Torikai, K., Ujihara, S., Matsumori, N., Murata, M. & Oshima, Y., May 15 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 10, p. 2824-2828 5 p.

Research output: Contribution to journalArticle

Surface Plasmon Resonance
Polyethers
Ladders
Surface plasmon resonance
Ciguatoxins
7 Citations (Scopus)

Synthesis of 25- 13c-amphotericin B methyl ester: A molecular probe for solid-state NMR measurements

Matsushita, N., Matsuo, Y., Tsuchikawa, H., Matsumori, N., Murata, M. & Oishi, T., Jul 20 2009, In : Chemistry Letters. 38, 2, p. 114-115 2 p.

Research output: Contribution to journalArticle

Molecular Probes
Amphotericin B
Nuclear magnetic resonance
Polyenes
Biological Products