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Research Output 1979 2019

  • 5484 Citations
  • 36 h-Index
  • 89 Article
  • 10 Review article
  • 1 Chapter
  • 1 Comment/debate
2019

Differential genomic destabilisation in human cells with pathogenic MSH2 mutations introduced by genome editing

Hayashida, G., Shioi, S., Hidaka, K., Fujikane, R., Hidaka, M., Tsurimoto, T., Tsuzuki, T., Oda, S. & Nakatsu, Y., Apr 15 2019, In : Experimental Cell Research. 377, 1-2, p. 24-35 12 p.

Research output: Contribution to journalArticle

Open Access
Microsatellite Instability
DNA Mismatch Repair
Mutation
Microsatellite Repeats
Hereditary Nonpolyposis Colorectal Neoplasms

Specific basic patch-dependent multimerization of Saccharomyces cerevisiae ORC on single-stranded DNA promotes ATP hydrolysis

Kawakami, H., Muraoka, R., Ohashi, E., Kawabata, K., Kanamoto, S., Chichibu, T., Tsurimoto, T. & Katayama, T., Jan 1 2019, In : Genes to Cells.

Research output: Contribution to journalArticle

Origin Recognition Complex
Single-Stranded DNA
Saccharomyces cerevisiae
Hydrolysis
Adenosine Triphosphate
2018
4 Citations (Scopus)

Inhibition of DNA replication by an anti-PCNA aptamer/PCNA complex

Kowalska, E., Bartnicki, F., Fujisawa, R., Bonarek, P., Hermanowicz, P., Tsurimoto, T., Muszynska, K. & Strzalka, W., Jan 1 2018, In : Nucleic acids research. 46, 1, p. 25-41 17 p.

Research output: Contribution to journalArticle

Proliferating Cell Nuclear Antigen
DNA Replication
DNA-Directed DNA Polymerase
SELEX Aptamer Technique
Nucleotide Aptamers
2017
2 Citations (Scopus)

Functions of multiple clamp and clamp-loader complexes in eukaryotic DNA replication

Ohashi, E. & Tsurimoto, T., Jan 1 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 135-162 28 p. (Advances in Experimental Medicine and Biology; vol. 1042).

Research output: Chapter in Book/Report/Conference proceedingChapter

Replication Protein C
Loaders
Clamping devices
Proliferating Cell Nuclear Antigen
DNA Replication
6 Citations (Scopus)

Human CTF18-RFC clamp-loader complexed with non-synthesising DNA polymerase ϵ efficiently loads the PCNA sliding clamp

Fujisawa, R., Ohashi, E., Hirota, K. & Tsurimoto, T., Jan 1 2017, In : Nucleic acids research. 45, 8, p. 4550-4563 14 p.

Research output: Contribution to journalArticle

Proliferating Cell Nuclear Antigen
DNA-Directed DNA Polymerase
DNA
Proteins
6 Citations (Scopus)

The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C)

Tsuda, M., Terada, K., Ooka, M., Kobayashi, K., Sasanuma, H., Fujisawa, R., Tsurimoto, T., Yamamoto, J., Iwai, S., Kadoda, K., Akagawa, R., Huang, S. Y. N., Pommier, Y., Sale, J. E., Takeda, S. & Hirota, K., Jan 1 2017, In : Oncotarget. 8, 20, p. 33457-33474 18 p.

Research output: Contribution to journalArticle

Exonucleases
Cytarabine
Trifluridine
Fluorouracil
DNA-Directed DNA Polymerase
2016
10 Citations (Scopus)

Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells

Yang, C. C., Suzuki, M., Yamakawa, S., Uno, S., Ishii, A., Yamazaki, S., Fukatsu, R., Fujisawa, R., Sakimura, K., Tsurimoto, T. & Masai, H., Jul 12 2016, In : Nature communications. 7, 12135.

Research output: Contribution to journalArticle

phosphorylation
Phosphorylation
knockout mice
DNA Replication
Phosphotransferases
8 Citations (Scopus)

Conserved interaction of Ctf18-RFC with DNA polymerase ε is critical for maintenance of genome stability in Saccharomyces cerevisiae

Okimoto, H., Tanaka, S., Araki, H., Ohashi, E. & Tsurimoto, T., May 1 2016, In : Genes to Cells. 21, 5, p. 482-491 10 p.

Research output: Contribution to journalArticle

Saccharomycetales
Genomic Instability
Proliferating Cell Nuclear Antigen
DNA-Directed DNA Polymerase
Saccharomyces cerevisiae
19 Citations (Scopus)

In vivo evidence for translesion synthesis by the replicative DNA polymerase δ

Hirota, K., Tsuda, M., Mohiuddin, Tsurimoto, T., Cohen, I. S., Livneh, Z., Kobayashi, K., Narita, T., Nishihara, K., Murai, J., Iwai, S., Guilbaud, G., Sale, J. E. & Takeda, S., Sep 6 2016, In : Nucleic acids research. 44, 15, p. 7242-7250 9 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Holoenzymes
Mutagenesis
Base Pairing
Molecular Biology
13 Citations (Scopus)

MutSα maintains the mismatch repair capability by inhibiting PCNA unloading

Kawasoe, Y., Tsurimoto, T., Nakagawa, T., Masukata, H. & Takahashi, T., Jul 12 2016, In : eLife. 5, 2016JULY, e15155.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Proliferating Cell Nuclear Antigen
Unloading
Repair
DNA
1 Citation (Scopus)
Origin Recognition Complex
Saccharomyces cerevisiae
Yeasts
Genetic Phenomena
Saccharomycetales
2015
4 Citations (Scopus)

Intramolecular binding of the Rad9 C terminus in the checkpoint clamp Rad9-Hus1-Rad1 is closely linked with its DNA binding

Takeishi, Y., Iwaya-Omi, R., Ohashi, E. & Tsurimoto, T., Aug 7 2015, In : Journal of Biological Chemistry. 290, 32, p. 19923-19932 10 p.

Research output: Contribution to journalArticle

Clamping devices
Tail
DNA
Amino Acids
DNA Damage
2 Citations (Scopus)

Short CCG repeat in huntingtin gene is an obstacle for replicative DNA polymerases, potentially hampering progression of replication fork

Le, H. P., Masuda, Y., Tsurimoto, T., Maki, S., Katayama, T., Furukohri, A. & Maki, H., Oct 1 2015, In : Genes to Cells. 20, 10, p. 817-833 17 p.

Research output: Contribution to journalArticle

Trinucleotide Repeats
DNA-Directed DNA Polymerase
DNA Polymerase III
DNA Replication
Trinucleotide Repeat Expansion
6 Citations (Scopus)

Specific binding of eukaryotic ORC to DNA replication origins depends on highly conserved basic residues

Kawakami, H., Ohashi, E., Kanamoto, S., Tsurimoto, T. & Katayama, T., Oct 12 2015, In : Scientific reports. 5, 14929.

Research output: Contribution to journalArticle

Origin Recognition Complex
Replication Origin
DNA Replication
DNA
Eukaryota
22 Citations (Scopus)

The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ

Hirota, K., Yoshikiyo, K., Guilbaud, G., Tsurimoto, T., Murai, J., Tsuda, M., Phillips, L. G., Narita, T., Nishihara, K., Kobayashi, K., Yamada, K., Nakamura, J., Pommier, Y., Lehmann, A., Sale, J. E. & Takeda, S., Jan 1 2015, In : Nucleic acids research. 43, 3, p. 1671-1683 13 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Mutagenesis
Holoenzymes
DNA
Saccharomyces cerevisiae
16 Citations (Scopus)

Interaction between Rad9-Hus1-Rad1 and TopBP1 activates ATR-ATRIP and promotes TopBP1 recruitment to sites of UV-damage

Ohashi, E., Takeishi, Y., Ueda, S. & Tsurimoto, T., Sep 1 2014, In : DNA Repair. 21, p. 1-11 11 p.

Research output: Contribution to journalArticle

DNA Damage
DNA
Chemical activation
Casein Kinase II
Cells
29 Citations (Scopus)

Kaposi's sarcoma-associated herpesvirus LANA recruits the DNA polymerase clamp loader to mediate efficient replication and virus persistence

Sun, Q., Tsurimoto, T., Juillard, F., Li, L., Li, S., De León Vázquez, E., Chen, S. & Kaye, K., Aug 12 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 32, p. 11816-11821 6 p.

Research output: Contribution to journalArticle

Human Herpesvirus 8
DNA-Directed DNA Polymerase
Virus Replication
Replication Protein C
Proliferating Cell Nuclear Antigen
2013

Efficient long DNA gap-filling in a mammalian cell-free system: A potential new in vitro DNA replication assay

Nakao, S., Zhang, S., Vaara, M., Syväoja, J. E., Lee, M. Y., Tsurimoto, T., Karran, P. & Oda, S., Feb 1 2013, In : Biochimie. 95, 2, p. 320-328 9 p.

Research output: Contribution to journalArticle

Cell-Free System
DNA Replication
Assays
Cells
DNA
11 Citations (Scopus)

RAD5a ubiquitin ligase is involved in ubiquitination of Arabidopsis thaliana proliferating cell nuclear antigen

Strzalka, W., Bartnicki, F., Pels, K., Jakubowska, A., Tsurimoto, T. & Tanaka, K., Mar 1 2013, In : Journal of Experimental Botany. 64, 4, p. 859-869 11 p.

Research output: Contribution to journalArticle

proliferating cell nuclear antigen
Ubiquitination
Proliferating Cell Nuclear Antigen
Ligases
ubiquitin
2012
16 Citations (Scopus)
Origin Recognition Complex
Nuclear Antigens
Human Herpesvirus 4
Viruses
Proteins
11 Citations (Scopus)

Interaction of heliquinomycin with single-stranded DNA inhibits MCM4/6/7 helicase

Sugiyama, T., Chino, M., Tsurimoto, T., Nozaki, N. & Ishimi, Y., Feb 1 2012, In : Journal of Biochemistry. 151, 2, p. 129-137 9 p.

Research output: Contribution to journalArticle

Single-Stranded DNA
DNA Helicases
DNA Replication
DNA
Inhibitory Concentration 50
7 Citations (Scopus)
HeLa Cells
Serine
DNA Damage
Phosphorylation
Small Interfering RNA
2011
118 Citations (Scopus)

Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

Hayashi-Takanaka, Y., Yamagata, K., Wakayama, T., Stasevich, T. J., Kainuma, T., Tsurimoto, T., Tachibana, M., Shinkai, Y., Kurumizaka, H., Nozaki, N. & Kimura, H., Aug 1 2011, In : Nucleic acids research. 39, 15, p. 6475-6488 14 p.

Research output: Contribution to journalArticle

Histone Code
Epigenomics
Acetylation
Embryonic Development
X Chromosome
2 Citations (Scopus)

Werner interacting protein 1 promotes binding of werner protein to template-primer DNA

Kanamori, M., Seki, M., Yoshimura, A., Tsurimoto, T., Tada, S. & Enomoto, T., Aug 1 2011, In : Biological and Pharmaceutical Bulletin. 34, 8, p. 1314-1318 5 p.

Research output: Contribution to journalArticle

DNA Primers
Carrier Proteins
Proteins
DNA
Werner Syndrome
2010
29 Citations (Scopus)

Casein kinase 2-dependent phosphorylation of human Rad9 mediates the interaction between human Rad9-Hus1-Rad1 complex and TopBP1

Takeishi, Y., Ohashi, E., Ogawa, K., Masai, H., Obuse, C. & Tsurimoto, T., Jun 1 2010, In : Genes to Cells. 15, 7, p. 761-771 11 p.

Research output: Contribution to journalArticle

Casein Kinase II
Phosphorylation
Serine
Methane
HeLa Cells
15 Citations (Scopus)

Human replicative DNA polymerase δ can bypass T-T (6-4) ultraviolet photoproducts on template strands

Narita, T., Tsurimoto, T., Yamamoto, J., Nishihara, K., Ogawa, K., Ohashi, E., Evans, T., Iwai, S., Takeda, S. & Hirota, K., Dec 1 2010, In : Genes to Cells. 15, 12, p. 1228-1239 12 p.

Research output: Contribution to journalArticle

Pyrimidinones
DNA-Directed DNA Polymerase
Pyrimidine Dimers
Exonucleases
Nucleotides
26 Citations (Scopus)
Replication Protein C
Loaders
Proliferating Cell Nuclear Antigen
DNA-Directed DNA Polymerase
DNA
2009
Multiprotein Complexes
Replication Origin
Proliferating Cell Nuclear Antigen
DNA-Directed DNA Polymerase
DNA Replication

[Regulation of the replication fork activity by clamp and clamp loader complexes].

Tsurimoto, T., Mar 2009, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 54, 4 Suppl, p. 374-379 6 p.

Research output: Contribution to journalReview article

Replication Protein C
Genetic Epigenesis
Saccharomyces cerevisiae Proteins
Ubiquitination
Proliferating Cell Nuclear Antigen

Function of multiple clamp and loader systems in eukaryotic chromosome replication

Shiomi, Y. & Tsurimoto, T., Sep 9 2009, In : Seikagaku. 81, 5, p. 386-389 4 p.

Research output: Contribution to journalReview article

Replication Protein C
Saccharomyces cerevisiae Proteins
Cell Cycle Proteins
Loaders
Clamping devices
16 Citations (Scopus)
Proteins
DNA Primers
DNA
Werner Syndrome
Saccharomycetales
16 Citations (Scopus)

Physical and functional interaction between WRNIP1 and RAD18

Yoshimura, A., Seki, M., Kanamori, M., Tateishi, S., Tsurimoto, T., Tada, S. & Enomoto, T., Jul 14 2009, In : Genes and Genetic Systems. 84, 2, p. 171-178 8 p.

Research output: Contribution to journalArticle

Proteins
DNA Primers
DNA
Werner Syndrome
Saccharomycetales
2008
179 Citations (Scopus)

CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during s phase and after UV irradiation

Nishitani, H., Shiomi, Y., Iida, H., Michishita, M., Takami, T. & Tsurimoto, T., Oct 24 2008, In : Journal of Biological Chemistry. 283, 43, p. 29045-29052 8 p.

Research output: Contribution to journalArticle

Proliferating Cell Nuclear Antigen
Irradiation
S Phase
Proteolysis
G2 Phase
20 Citations (Scopus)

DNA damage-induced ubiquitylation of RFC2 subunit of replication factor C complex

Tomida, J., Masuda, Y., Hiroaki, H., Ishikawa, T., Song, I., Tsurimoto, T., Tateishi, S., Shiomi, T., Kamei, Y., Kim, J., Kamiya, K., Vaziri, C., Ohmori, H. & Todo, T., Apr 4 2008, In : Journal of Biological Chemistry. 283, 14, p. 9071-9079 9 p.

Research output: Contribution to journalArticle

Replication Protein C
Replication Protein A
Ubiquitination
Proliferating Cell Nuclear Antigen
DNA Damage
41 Citations (Scopus)

Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks

Tsuji, Y., Watanabe, K., Araki, K., Shinohara, M., Yamagata, Y., Tsurimoto, T., Hanaoka, F., Yamamura, K. I., Yamaizumi, M. & Tateishi, S., Apr 1 2008, In : Genes to Cells. 13, 4, p. 343-354 12 p.

Research output: Contribution to journalArticle

Single-Stranded DNA
DNA Damage
DNA
Proteins
Ubiquitination
2007
20 Citations (Scopus)

A second proliferating cell nuclear antigen loader complex, Ctf18-replication factor C, stimulates DNA polymerase η activity

Shiomi, Y., Masutani, C., Hanaoka, F., Kimura, H. & Tsurimoto, T., Jul 20 2007, In : Journal of Biological Chemistry. 282, 29, p. 20906-20914 9 p.

Research output: Contribution to journalArticle

Replication Protein C
Loaders
Proliferating Cell Nuclear Antigen
DNA-Directed DNA Polymerase
Chromosomes
2006
274 Citations (Scopus)

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis

Nishitani, H., Sugimoto, N., Roukos, V., Nakanishi, Y., Saijo, M., Obuse, C., Tsurimoto, T., Nakayama, K., Nakayama, K., Fujita, M., Lygerou, Z. & Nishimoto, T., Mar 8 2006, In : EMBO Journal. 25, 5, p. 1126-1136 11 p.

Research output: Contribution to journalArticle

Proteolysis
Ubiquitin-Protein Ligases
G2 Phase
S Phase
Amino Acids
2005
41 Citations (Scopus)

Human Werner helicase interacting protein 1 (WRNIP1) functions as novel modulator for DNA polymerase δ

Tsurimoto, T., Shinozaki, A., Yano, M., Seki, M. & Enomoto, T., Jan 2005, In : Genes to Cells. 10, 1, p. 13-22 10 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Adenosine Triphosphatases
Proteins
DNA
Adenosine Triphosphate
2004
396 Citations (Scopus)

Rad18 guides polη to replication stalling sites through physical interaction and PCNA monoubiquitination

Watanabe, K., Tateishi, S., Kawasuji, M., Tsurimoto, T., Inoue, H. & Yamaizumi, M., Oct 1 2004, In : EMBO Journal. 23, 19, p. 3886-3896 11 p.

Research output: Contribution to journalArticle

Proliferating Cell Nuclear Antigen
Irradiation
DNA-Directed DNA Polymerase
DNA
DNA Replication
33 Citations (Scopus)

The reconstituted human Chl12-RFC complex functions as a second PCNA loader

Shiomi, Y., Shinozaki, A., Sugimoto, K., Usukura, J., Obuse, C. & Tsurimoto, T., Apr 1 2004, In : Genes to Cells. 9, 4, p. 279-290 12 p.

Research output: Contribution to journalArticle

Replication Protein C
Proliferating Cell Nuclear Antigen
DNA
Circular DNA
Chromatids
2003
58 Citations (Scopus)

The ORC1 cycle in human cells: II. Dynamic changes in the human ORC complex during the cell cycle

Ohta, S., Tatsumi, Y., Fujita, M., Tsurimoto, T. & Obuse, C., Oct 17 2003, In : Journal of Biological Chemistry. 278, 42, p. 41535-41540 6 p.

Research output: Contribution to journalArticle

Origin Recognition Complex
Cell Cycle
Cells
Chromatin
Multicarrier modulation
73 Citations (Scopus)

The ORC1 cycle in human cells: I. Cell cycle-regulated oscillation of human ORC1

Tatsumi, Y., Ohta, S., Kimura, H., Tsurimoto, T. & Obuse, C., Oct 17 2003, In : Journal of Biological Chemistry. 278, 42, p. 41528-41534 7 p.

Research output: Contribution to journalArticle

Origin Recognition Complex
S Phase
Cell Cycle
Cells
Aphidicolin
2002
69 Citations (Scopus)
Forensic Anthropology
Proliferating Cell Nuclear Antigen
Proteomics
Carrier Proteins
Cells
18 Citations (Scopus)

Binding kinetics of the toroid-shaped PCNA to DNA strands on a 27 MHz quartz crystal microbalance

Furusawa, H., Kitamura, Y., Hagiwara, N., Tsurimoto, T. & Okahata, Y., May 17 2002, In : ChemPhysChem. 3, 5, p. 446-448 3 p.

Research output: Contribution to journalArticle

Pregnenolone Carbonitrile
toroids
Quartz crystal microbalances
antigens
quartz crystals
77 Citations (Scopus)

Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9-1-1 and Rad17-RFC

Shiomi, Y., Shinozaki, A., Nakada, D., Sugimoto, K., Usukura, J., Obuse, C. & Tsurimoto, T., Aug 1 2002, In : Genes to Cells. 7, 8, p. 861-868 8 p.

Research output: Contribution to journalArticle

Replication Protein C
Proliferating Cell Nuclear Antigen
Proteins
rad9 protein
Insect Proteins

DNA polymerase delta

Tsurimoto, T., Jan 1 2002, In : Seikagaku. The Journal of Japanese Biochemical Society. 74, 3, p. 192-196 5 p.

Research output: Contribution to journalReview article

Replication Protein C
RecQ Helicases
DNA Polymerase III
DNA Helicases
Signal transduction
86 Citations (Scopus)

PCNA clamp facilitates action of DNA cytosine methyltransferase 1 on hemimethylated DNA

Iida, T., Suetake, I., Tajima, S., Morioka, H., Ohta, S., Obuse, C. & Tsurimoto, T., Oct 1 2002, In : Genes to Cells. 7, 10, p. 997-1007 11 p.

Research output: Contribution to journalArticle

Cytosine
Proliferating Cell Nuclear Antigen
Methyltransferases
DNA
DNA Methylation
5 Citations (Scopus)

Scheduled conversion of replication complex architecture at replication origins of Saccharomyces cerevisiae during the cell cycle

Tadokoro, R., Fujita, M., Miura, H., Shirahige, K., Yoshikawa, H., Tsurimoto, T. & Obuse, C., May 3 2002, In : Journal of Biological Chemistry. 277, 18, p. 15881-15889 9 p.

Research output: Contribution to journalArticle

Replication Origin
Yeast
Saccharomyces cerevisiae
Cell Cycle
Cells
2001
22 Citations (Scopus)

Funcitonal interactions of an archael sliding clamp with mammalian clamp loader and DNA polymerase δ

Ishino, Y., Tsurimoto, T., Ishino, S. & Cann, I. K. O., Sep 8 2001, In : Genes to Cells. 6, 8, p. 699-706 8 p.

Research output: Contribution to journalArticle

Proliferating Cell Nuclear Antigen
DNA-Directed DNA Polymerase
Pyrococcus furiosus
DNA Replication
Replication Protein C