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Research Output

  • 5604 Citations
  • 37 h-Index
  • 89 Article
  • 10 Review article
  • 2 Comment/debate
  • 1 Chapter
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Article
2019

Differential genomic destabilisation in human cells with pathogenic MSH2 mutations introduced by genome editing

Hayashida, G., Shioi, S., Hidaka, K., Fujikane, R., Hidaka, M., Tsurimoto, T., Tsuzuki, T., Oda, S. & Nakatsu, Y., Apr 15 2019, In : Experimental Cell Research. 377, 1-2, p. 24-35 12 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Specific basic patch-dependent multimerization of Saccharomyces cerevisiae ORC on single-stranded DNA promotes ATP hydrolysis

Kawakami, H., Muraoka, R., Ohashi, E., Kawabata, K., Kanamoto, S., Chichibu, T., Tsurimoto, T. & Katayama, T., Sep 1 2019, In : Genes to Cells. 24, 9, p. 608-618 11 p.

Research output: Contribution to journalArticle

2018

Inhibition of DNA replication by an anti-PCNA aptamer/PCNA complex

Kowalska, E., Bartnicki, F., Fujisawa, R., Bonarek, P., Hermanowicz, P., Tsurimoto, T., Muszynska, K. & Strzalka, W., Jan 1 2018, In : Nucleic acids research. 46, 1, p. 25-41 17 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

Human CTF18-RFC clamp-loader complexed with non-synthesising DNA polymerase ϵ efficiently loads the PCNA sliding clamp

Fujisawa, R., Ohashi, E., Hirota, K. & Tsurimoto, T., Jan 1 2017, In : Nucleic acids research. 45, 8, p. 4550-4563 14 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C)

Tsuda, M., Terada, K., Ooka, M., Kobayashi, K., Sasanuma, H., Fujisawa, R., Tsurimoto, T., Yamamoto, J., Iwai, S., Kadoda, K., Akagawa, R., Huang, S. Y. N., Pommier, Y., Sale, J. E., Takeda, S. & Hirota, K., Jan 1 2017, In : Oncotarget. 8, 20, p. 33457-33474 18 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2016

Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells

Yang, C. C., Suzuki, M., Yamakawa, S., Uno, S., Ishii, A., Yamazaki, S., Fukatsu, R., Fujisawa, R., Sakimura, K., Tsurimoto, T. & Masai, H., Jul 12 2016, In : Nature communications. 7, 12135.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Conserved interaction of Ctf18-RFC with DNA polymerase ε is critical for maintenance of genome stability in Saccharomyces cerevisiae

Okimoto, H., Tanaka, S., Araki, H., Ohashi, E. & Tsurimoto, T., May 1 2016, In : Genes to Cells. 21, 5, p. 482-491 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

In vivo evidence for translesion synthesis by the replicative DNA polymerase δ

Hirota, K., Tsuda, M., Mohiuddin, Tsurimoto, T., Cohen, I. S., Livneh, Z., Kobayashi, K., Narita, T., Nishihara, K., Murai, J., Iwai, S., Guilbaud, G., Sale, J. E. & Takeda, S., Sep 6 2016, In : Nucleic acids research. 44, 15, p. 7242-7250 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

MutSα maintains the mismatch repair capability by inhibiting PCNA unloading

Kawasoe, Y., Tsurimoto, T., Nakagawa, T., Masukata, H. & Takahashi, T. S., Jul 12 2016, In : eLife. 5, 2016JULY, e15155.

Research output: Contribution to journalArticle

14 Citations (Scopus)
1 Citation (Scopus)
2015

Intramolecular binding of the Rad9 C terminus in the checkpoint clamp Rad9-Hus1-Rad1 is closely linked with its DNA binding

Takeishi, Y., Iwaya-Omi, R., Ohashi, E. & Tsurimoto, T., Aug 7 2015, In : Journal of Biological Chemistry. 290, 32, p. 19923-19932 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Short CCG repeat in huntingtin gene is an obstacle for replicative DNA polymerases, potentially hampering progression of replication fork

Le, H. P., Masuda, Y., Tsurimoto, T., Maki, S., Katayama, T., Furukohri, A. & Maki, H., Oct 2015, In : Genes to Cells. 20, 10, p. 817-833 17 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Specific binding of eukaryotic ORC to DNA replication origins depends on highly conserved basic residues

Kawakami, H., Ohashi, E., Kanamoto, S., Tsurimoto, T. & Katayama, T., Oct 12 2015, In : Scientific reports. 5, 14929.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ

Hirota, K., Yoshikiyo, K., Guilbaud, G., Tsurimoto, T., Murai, J., Tsuda, M., Phillips, L. G., Narita, T., Nishihara, K., Kobayashi, K., Yamada, K., Nakamura, J., Pommier, Y., Lehmann, A., Sale, J. E. & Takeda, S., Jan 1 2015, In : Nucleic acids research. 43, 3, p. 1671-1683 13 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2014

Interaction between Rad9-Hus1-Rad1 and TopBP1 activates ATR-ATRIP and promotes TopBP1 recruitment to sites of UV-damage

Ohashi, E., Takeishi, Y., Ueda, S. & Tsurimoto, T., Sep 1 2014, In : DNA Repair. 21, p. 1-11 11 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Kaposi's sarcoma-associated herpesvirus LANA recruits the DNA polymerase clamp loader to mediate efficient replication and virus persistence

Sun, Q., Tsurimoto, T., Juillard, F., Li, L., Li, S., De León Vázquez, E., Chen, S. & Kaye, K., Aug 12 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 32, p. 11816-11821 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2013

Efficient long DNA gap-filling in a mammalian cell-free system: A potential new in vitro DNA replication assay

Nakao, S., Zhang, S., Vaara, M., Syväoja, J. E., Lee, M. Y., Tsurimoto, T., Karran, P. & Oda, S., Feb 1 2013, In : Biochimie. 95, 2, p. 320-328 9 p.

Research output: Contribution to journalArticle

RAD5a ubiquitin ligase is involved in ubiquitination of Arabidopsis thaliana proliferating cell nuclear antigen

Strzalka, W., Bartnicki, F., Pels, K., Jakubowska, A., Tsurimoto, T. & Tanaka, K., Mar 1 2013, In : Journal of Experimental Botany. 64, 4, p. 859-869 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2012
16 Citations (Scopus)

Interaction of heliquinomycin with single-stranded DNA inhibits MCM4/6/7 helicase

Sugiyama, T., Chino, M., Tsurimoto, T., Nozaki, N. & Ishimi, Y., Feb 1 2012, In : Journal of Biochemistry. 151, 2, p. 129-137 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
7 Citations (Scopus)
2011

Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

Hayashi-Takanaka, Y., Yamagata, K., Wakayama, T., Stasevich, T. J., Kainuma, T., Tsurimoto, T., Tachibana, M., Shinkai, Y., Kurumizaka, H., Nozaki, N. & Kimura, H., Aug 1 2011, In : Nucleic acids research. 39, 15, p. 6475-6488 14 p.

Research output: Contribution to journalArticle

125 Citations (Scopus)

Werner interacting protein 1 promotes binding of werner protein to template-primer DNA

Kanamori, M., Seki, M., Yoshimura, A., Tsurimoto, T., Tada, S. & Enomoto, T., Aug 1 2011, In : Biological and Pharmaceutical Bulletin. 34, 8, p. 1314-1318 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2010

Casein kinase 2-dependent phosphorylation of human Rad9 mediates the interaction between human Rad9-Hus1-Rad1 complex and TopBP1

Takeishi, Y., Ohashi, E., Ogawa, K., Masai, H., Obuse, C. & Tsurimoto, T., Jun 1 2010, In : Genes to Cells. 15, 7, p. 761-771 11 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Human replicative DNA polymerase δ can bypass T-T (6-4) ultraviolet photoproducts on template strands

Narita, T., Tsurimoto, T., Yamamoto, J., Nishihara, K., Ogawa, K., Ohashi, E., Evans, T., Iwai, S., Takeda, S. & Hirota, K., Dec 1 2010, In : Genes to Cells. 15, 12, p. 1228-1239 12 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
29 Citations (Scopus)
2009

Physical and functional interaction between WRNIP1 and RAD18

Yoshimura, A., Seki, M., Kanamori, M., Tateishi, S., Tsurimoto, T., Tada, S. & Enomoto, T., Jul 14 2009, In : Genes and Genetic Systems. 84, 2, p. 171-178 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2008

CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during s phase and after UV irradiation

Nishitani, H., Shiomi, Y., Iida, H., Michishita, M., Takami, T. & Tsurimoto, T., Oct 24 2008, In : Journal of Biological Chemistry. 283, 43, p. 29045-29052 8 p.

Research output: Contribution to journalArticle

185 Citations (Scopus)

DNA damage-induced ubiquitylation of RFC2 subunit of replication factor C complex

Tomida, J., Masuda, Y., Hiroaki, H., Ishikawa, T., Song, I., Tsurimoto, T., Tateishi, S., Shiomi, T., Kamei, Y., Kim, J., Kamiya, K., Vaziri, C., Ohmori, H. & Todo, T., Apr 4 2008, In : Journal of Biological Chemistry. 283, 14, p. 9071-9079 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks

Tsuji, Y., Watanabe, K., Araki, K., Shinohara, M., Yamagata, Y., Tsurimoto, T., Hanaoka, F., Yamamura, K. I., Yamaizumi, M. & Tateishi, S., Apr 1 2008, In : Genes to Cells. 13, 4, p. 343-354 12 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2007

A second proliferating cell nuclear antigen loader complex, Ctf18-replication factor C, stimulates DNA polymerase η activity

Shiomi, Y., Masutani, C., Hanaoka, F., Kimura, H. & Tsurimoto, T., Jul 20 2007, In : Journal of Biological Chemistry. 282, 29, p. 20906-20914 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Dynamics of human replication factors in the elongation phase of DNA replication

Masuda, Y., Suzuki, M., Piao, J., Gu, Y., Tsurimoto, T. & Kamiya, K., Nov 1 2007, In : Nucleic acids research. 35, 20, p. 6904-6916 13 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)
2006

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis

Nishitani, H., Sugimoto, N., Roukos, V., Nakanishi, Y., Saijo, M., Obuse, C., Tsurimoto, T., Nakayama, K. I., Nakayama, K., Fujita, M., Lygerou, Z. & Nishimoto, T., Mar 8 2006, In : EMBO Journal. 25, 5, p. 1126-1136 11 p.

Research output: Contribution to journalArticle

279 Citations (Scopus)
2005

Human Werner helicase interacting protein 1 (WRNIP1) functions as novel modulator for DNA polymerase δ

Tsurimoto, T., Shinozaki, A., Yano, M., Seki, M. & Enomoto, T., Jan 1 2005, In : Genes to Cells. 10, 1, p. 13-22 10 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2004

Rad18 guides polη to replication stalling sites through physical interaction and PCNA monoubiquitination

Watanabe, K., Tateishi, S., Kawasuji, M., Tsurimoto, T., Inoue, H. & Yamaizumi, M., Oct 1 2004, In : EMBO Journal. 23, 19, p. 3886-3896 11 p.

Research output: Contribution to journalArticle

404 Citations (Scopus)

The reconstituted human Chl12-RFC complex functions as a second PCNA loader

Shiomi, Y., Shinozaki, A., Sugimoto, K., Usukura, J., Obuse, C. & Tsurimoto, T., Apr 1 2004, In : Genes to Cells. 9, 4, p. 279-290 12 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2003

The ORC1 cycle in human cells: I. Cell cycle-regulated oscillation of human ORC1

Tatsumi, Y., Ohta, S., Kimura, H., Tsurimoto, T. & Obuse, C., Oct 17 2003, In : Journal of Biological Chemistry. 278, 42, p. 41528-41534 7 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

The ORC1 cycle in human cells: II. Dynamic changes in the human ORC complex during the cell cycle

Ohta, S., Tatsumi, Y., Fujita, M., Tsurimoto, T. & Obuse, C., Oct 17 2003, In : Journal of Biological Chemistry. 278, 42, p. 41535-41540 6 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)
2002
71 Citations (Scopus)

Binding kinetics of the toroid-shaped PCNA to DNA strands on a 27 MHz quartz crystal microbalance

Furusawa, H., Kitamura, Y., Hagiwara, N., Tsurimoto, T. & Okahata, Y., May 17 2002, In : ChemPhysChem. 3, 5, p. 446-448 3 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9-1-1 and Rad17-RFC

Shiomi, Y., Shinozaki, A., Nakada, D., Sugimoto, K., Usukura, J., Obuse, C. & Tsurimoto, T., Aug 1 2002, In : Genes to Cells. 7, 8, p. 861-868 8 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)

PCNA clamp facilitates action of DNA cytosine methyltransferase 1 on hemimethylated DNA

Iida, T., Suetake, I., Tajima, S., Morioka, H., Ohta, S., Obuse, C. & Tsurimoto, T., Oct 1 2002, In : Genes to Cells. 7, 10, p. 997-1007 11 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

Scheduled conversion of replication complex architecture at replication origins of Saccharomyces cerevisiae during the cell cycle

Tadokoro, R., Fujita, M., Miura, H., Shirahige, K., Yoshikawa, H., Tsurimoto, T. & Obuse, C., May 3 2002, In : Journal of Biological Chemistry. 277, 18, p. 15881-15889 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2001

Funcitonal interactions of an archael sliding clamp with mammalian clamp loader and DNA polymerase δ

Ishino, Y., Tsurimoto, T., Ishino, S. & Cann, I. K. O., Sep 8 2001, In : Genes to Cells. 6, 8, p. 699-706 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

In vitro reconstitution of the end replication problem

Ohki, R., Tsurimoto, T. & Ishikawa, F., Aug 22 2001, In : Molecular and cellular biology. 21, 17, p. 5753-5766 14 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

The human homologue of fission yeast cdc27, p66, is a component of active human DNA polymerase δ

Shikata, K., Ohta, S., Yamada, K., Obuse, C., Yoshikawa, H. & Tsurimoto, T., May 2001, In : Journal of biochemistry. 129, 5, p. 699-708 10 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
2000

Association of human origin recognition complex 1 with chromatin DNA and nuclease-resistant nuclear structures

Tatsumi, Y., Tsurimoto, T., Shirahige, K., Yoshikawa, H. & Obuse, C., Feb 25 2000, In : Journal of Biological Chemistry. 275, 8, p. 5904-5910 7 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Atomic force microscopy with carbon nanotube probe resolves the subunit organization of protein complexes

Hohmura, K. I., Itokazu, Y., Yoshimura, S. H., Mizuguchi, G., Masamura, Y. S., Takeyasu, K., Shiomi, Y., Tsurimoto, T., Nishijima, H., Akita, S. & Nakayama, Y., Jan 1 2000, In : Journal of Electron Microscopy. 49, 3, p. 415-421 7 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

ATP-dependent structural change of the eukaryotic clamp-loader protein, replication factor C

Shiomi, Y., Usukura, J., Masamura, Y., Takeyasu, K., Nakayama, Y., Obuse, C., Yoshikawa, H. & Tsurimoto, T., Dec 19 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 26, p. 14127-14132 6 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription

Kitaura, H., Shinshi, M., Uchikoshi, Y., Ono, T., Tsurimoto, T., Yoshikawa, H., Iguchi-Ariga, S. M. M. & Ariga, H., Apr 7 2000, In : Journal of Biological Chemistry. 275, 14, p. 10477-10483 7 p.

Research output: Contribution to journalArticle

112 Citations (Scopus)