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Research Output 2010 2019

2019

Association between Axial Length and Myopic Maculopathy: The Hisayama Study

Hashimoto, S., Yasuda, M., Fujiwara, K., Ueda, E., Hata, J., Hirakawa, Y., Ninomiya, T. & Sonoda, K. H., Oct 2019, In : Ophthalmology Retina. 3, 10, p. 867-873 7 p.

Research output: Contribution to journalArticle

Open Access
Odds Ratio
Confidence Intervals
Atrophy
Macular Degeneration
ROC Curve
2 Citations (Scopus)

Association between Genetic Risk and Development of Type 2 Diabetes in a General Japanese Population: The Hisayama Study

Inaishi, J., Hirakawa, Y., Horikoshi, M., Akiyama, M., Higashioka, M., Yoshinari, M., Hata, J., Mukai, N., Kamatani, Y., Momozawa, Y., Kubo, M. & Ninomiya, T., Jun 19 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 8, p. 3213-3222 10 p.

Research output: Contribution to journalArticle

Medical problems
Type 2 Diabetes Mellitus
Population
Hazards
Precision Medicine

Association between Serum β-Alanine and Risk of Dementia

Hata, J., Ohara, T., Katakura, Y., Shimizu, K., Yamashita, S., Yoshida, D., Honda, T., Hirakawa, Y., Shibata, M., Sakata, S., Kitazono, T., Kuhara, S. & Ninomiya, T., Sep 1 2019, In : American journal of epidemiology. 188, 9, p. 1637-1645 9 p.

Research output: Contribution to journalArticle

Alanine
Dementia
Anserine
Carnosine
Confidence Intervals
13 Citations (Scopus)

Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality: An Individual-Level Pooled Analysis of 30 Cohort Studies

Marklund, M., Wu, J. H. Y., Imamura, F., Del Gobbo, L. C., Fretts, A., De Goede, J., Shi, P., Tintle, N., Wennberg, M., Aslibekyan, S., Chen, T. A., De Oliveira Otto, M. C., Hirakawa, Y., Eriksen, H. H., Kröger, J., Laguzzi, F., Lankinen, M., Murphy, R. A., Prem, K., Samieri, C. & 67 others, Virtanen, J., Wood, A. C., Wong, K., Yang, W. S., Zhou, X., Baylin, A., Boer, J. M. A., Brouwer, I. A., Campos, H., Chaves, P. H. M., Chien, K. L., De Faire, U., Djoussé, L., Eiriksdottir, G., El-Abbadi, N., Forouhi, N. G., Michael Gaziano, J., Geleijnse, J. M., Gigante, B., Giles, G., Guallar, E., Gudnason, V., Harris, T., Harris, W. S., Helmer, C., Hellenius, M. L., Hodge, A., Hu, F. B., Jacques, P. F., Jansson, J. H., Kalsbeek, A., Khaw, K. T., Koh, W. P., Laakso, M., Leander, K., Lin, H. J., Lind, L., Luben, R., Luo, J., Mcknight, B., Mursu, J., Ninomiya, T., Overvad, K., Psaty, B. M., Rimm, E., Schulze, M. B., Siscovick, D., Skjelbo Nielsen, M., Smith, A. V., Steffen, B. T., Steffen, L., Sun, Q., Sundström, J., Tsai, M. Y., Tunstall-Pedoe, H., Uusitupa, M. I. J., Van Dam, R. M., Veenstra, J., Monique Verschuren, W. M., Wareham, N., Willett, W., Woodward, M., Yuan, J. M., Micha, R., Lemaitre, R. N., Mozaffarian, D. & Risérus, U., May 21 2019, In : Circulation. 139, 21, p. 2422-2436 15 p.

Research output: Contribution to journalArticle

Omega-6 Fatty Acids
Linoleic Acid
Cohort Studies
Cardiovascular Diseases
Biomarkers

Coffee drinking and risk of all-cause mortality and cardiovascular diseases

Hirakawa, Y., Apr 1 2019, In : Circulation Journal. 83, 4, p. 711-712 2 p.

Research output: Contribution to journalEditorial

Open Access
Coffee
Drinking
Cardiovascular Diseases
Mortality
1 Citation (Scopus)

Dairy consumption and risk of functional disability in an elderly Japanese population: The Hisayama Study

Yoshida, D., Ohara, T., Hata, J., Shibata, M., Hirakawa, Y., Honda, T., Uchida, K., Takasugi, S., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Jun 1 2019, In : American Journal of Clinical Nutrition. 109, 6, p. 1664-1671 8 p.

Research output: Contribution to journalArticle

Activities of Daily Living
Population
Independent Living
Geriatrics
Mental Competency
8 Citations (Scopus)

Effects of blood pressure lowering on cardiovascular events, in the context of regression to the mean: a systematic review of randomized trials

Blood Pressure Lowering Treatment Trialists’ Collaboration, Jan 1 2019, In : Journal of hypertension. 37, 1, p. 16-23 8 p.

Research output: Contribution to journalArticle

Blood Pressure
Coronary Disease
Stroke
Therapeutics
MEDLINE

Glucose Tolerance Levels and Circumpapillary Retinal Nerve Fiber Layer Thickness in a General Japanese Population: The Hisayama Study

Fujiwara, K., Yasuda, M., Hata, J., Hirakawa, Y., Hashimoto, S., Ueda, E., Iwase, A., Araie, M., Yoshitomi, T., Ninomiya, T. & Sonoda, K., Sep 1 2019, In : American journal of ophthalmology. 205, p. 140-146 7 p.

Research output: Contribution to journalArticle

Nerve Fibers
Glucose
Population
Prediabetic State
Glucose Intolerance
13 Citations (Scopus)

Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial

ENCHANTED Investigators and Coordinators, Mar 2 2019, In : The Lancet. 393, 10174, p. 877-888 12 p.

Research output: Contribution to journalArticle

Stroke
Blood Pressure
Tissue Plasminogen Activator
Guidelines
Therapeutics
Exercise
Population
Independent Living
Japan
Light

Measurement of prostaglandin metabolites is useful in diagnosis of small bowel ulcerations

Matsuno, Y., Umeno, J., Esaki, M., Hirakawa, Y., Fuyuno, Y., Okamoto, Y., Hirano, A., Yasukawa, S., Hirai, F., Matsui, T., Hosomi, S., Watanabe, K., Hosoe, N., Ogata, H., Hisamatsu, T., Yanai, S., Kochi, S., Kurahara, K., Yao, T., Torisu, T. & 2 others, Kitazono, T. & Matsumoto, T., Jan 1 2019, In : World Journal of Gastroenterology. 25, 14, p. 1753-1763 11 p.

Research output: Contribution to journalArticle

Open Access
Prostaglandins
Crohn Disease
Prostaglandins E
Genes
ROC Curve
Open Access
Brain Natriuretic Peptide
Dementia
Population
Serum
Alzheimer Disease
Open Access
Diabetes Mellitus
Insulin Resistance
Population
Homeostasis
Energy Intake
1 Citation (Scopus)

Physical component quality of life reflects the impact of time and moderate chronic kidney disease, unlike SF-6D utility and mental component SF-36 quality of life: An AusDiab analysis

Wong, M. G., Ninomiya, T., Liyanage, T., Sukkar, L., Hirakawa, Y., Wang, Y., Wyld, M. L. R., Morton, R. L., Chadban, S., Howard, K. & Jardine, M. J., Jun 2019, In : Nephrology. 24, 6, p. 605-614 10 p.

Research output: Contribution to journalArticle

Glomerular Filtration Rate
Chronic Renal Insufficiency
Albuminuria
Quality of Life
Social Adjustment

Prevalence of adult epilepsy in a general Japanese population: The Hisayama study

Tanaka, A., Hata, J., Akamatsu, N., Mukai, N., Hirakawa, Y., Yoshida, D., Kishimoto, H., Ohara, T., Mizuno, T., Tsuji, S., Kitazono, T. & Ninomiya, T., Mar 2019, In : Epilepsia Open. 4, 1, p. 182-186 5 p.

Research output: Contribution to journalArticle

Open Access
Epilepsy
Population
Cerebrovascular Disorders
Confidence Intervals
Tonic-Clonic Epilepsy
Open Access
Resistin
Eicosapentaenoic Acid
Docosahexaenoic Acids
Arachidonic Acid
Serum

Serum ethylamine levels as an indicator of l-theanine consumption and the risk of type 2 diabetes in a general Japanese population: The hisayama study

Ninomiya, T., Kanzaki, N., Hirakawa, Y., Yoshinari, M., Higashioka, M., Honda, T., Shibata, M., Sakata, S., Yoshida, D., Teramoto, T., Takemoto, S., Nishimoto, S., Hata, J. & Kitazono, T., Jan 1 2019, In : Diabetes care. 42, 7, p. 1234-1240 7 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Serum
Population
Eating
Independent Living
1 Citation (Scopus)

Serum Soluble Triggering Receptor Expressed on Myeloid Cells 2 as a Biomarker for Incident Dementia: The Hisayama Study

Ohara, T., Hata, J., Tanaka, M., Honda, T., Yamakage, H., Yoshida, D., Inoue, T., Hirakawa, Y., Kusakabe, T., Shibata, M., Teraoka, T., Kitazono, T., Kanba, S., Satoh-Asahara, N. & Ninomiya, T., Jan 1 2019, In : Annals of Neurology. 85, 1, p. 47-58 12 p.

Research output: Contribution to journalArticle

Myeloid Cells
Dementia
Biomarkers
Alzheimer Disease
Vascular Dementia
Open Access
Cross-Sectional Studies
Smoking
Population
Japan
Environmental Pollution
2 Citations (Scopus)
Prediabetic State
Type 2 Diabetes Mellitus
Body Mass Index
Glucose Tolerance Test
Obesity
2018
3 Citations (Scopus)
Independent Living
Vascular Dementia
Albuminuria
Alzheimer Disease
Glomerular Filtration Rate
1 Citation (Scopus)
Myeloid Cells
Insulin Resistance
Serum
Population
Fats
5 Citations (Scopus)
Dementia
Sleep
Mortality
Hypnotics and Sedatives
Confidence Intervals
4 Citations (Scopus)

Development and validation of a risk assessment tool for gastric cancer in a general Japanese population

Iida, M., Ikeda, F., Hata, J., Hirakawa, Y., Ohara, T., Mukai, N., Yoshida, D., Yonemoto, K., Esaki, M., Kitazono, T., Kiyohara, Y. & Ninomiya, T., May 1 2018, In : Gastric Cancer. 21, 3, p. 383-390 8 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Population
Pepsinogen A
Proportional Hazards Models
Helicobacter pylori
1 Citation (Scopus)
Cardiovascular Diseases
Decision Support Techniques
Coronary Disease
Stroke
Blood Pressure
2 Citations (Scopus)

Insulin and glucose-lowering agents for treating people with diabetes and chronic kidney disease

Lo, C., Toyama, T., Wang, Y., Lin, J., Hirakawa, Y., Jun, M., Cass, A., Hawley, C. M., Pilmore, H., Badve, S. V., Perkovic, V. & Zoungas, S., Sep 24 2018, In : Cochrane Database of Systematic Reviews. 2018, 9, CD011798.

Research output: Contribution to journalReview article

Sodium-Glucose Transporter 2
Chronic Renal Insufficiency
Symporters
Dipeptidyl-Peptidase IV Inhibitors
Placebos
7 Citations (Scopus)

Prevalence of and risk factors for cerebral microbleeds in a general Japanese elderly community

Yubi, T., Hata, J., Ohara, T., Mukai, N., Hirakawa, Y., Yoshida, D., Gotoh, S., Hirabayashi, N., Furuta, Y., Ago, T., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Jun 1 2018, In : Neurology: Clinical Practice. 8, 3, p. 223-231 9 p.

Research output: Contribution to journalReview article

Cross-Sectional Studies
Logistic Models
Cholesterol
Regression Analysis
Hypertension
1 Citation (Scopus)

Secular trends in the incidence, risk factors, and prognosis of transient ischemic attack in Japan: The Hisayama Study

Furuta, Y., Hata, J., Mukai, N., Hirakawa, Y., Ago, T., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Jun 2018, In : Atherosclerosis. 273, p. 84-90 7 p.

Research output: Contribution to journalArticle

Transient Ischemic Attack
Japan
Incidence
Stroke
Blood Pressure
2017
10 Citations (Scopus)

Age-specific impact of diabetes mellitus on the risk of cardiovascular mortality: An overview from the evidence for Cardiovascular Prevention from Observational Cohorts in the Japan Research Group (EPOCH-JAPAN)

the Evidence for Cardiovascular Prevention From Observational Cohorts in Japan Research Group (EPOCH-JAPAN), Jan 1 2017, In : Journal of epidemiology. 27, 3, p. 123-129 7 p.

Research output: Contribution to journalArticle

Diabetes Mellitus
Japan
Cardiovascular Diseases
Mortality
Research
4 Citations (Scopus)
Hyperglycemia
Alzheimer Disease
Hemoglobins
Glycosylated Hemoglobin A
Hazards
6 Citations (Scopus)
Vitamin D
Cause of Death
Respiratory Tract Infections
Cardiovascular Infections
Serum
5 Citations (Scopus)

Cumulative in-trial and post-trial effects of blood pressure and lipid lowering: Systematic review and meta-analysis

Hirakawa, Y., Arima, H., Rodgers, A., Woodward, M. & Chalmers, J., Jan 1 2017, In : Journal of Hypertension. 35, 5, p. 905-913 9 p.

Research output: Contribution to journalReview article

Meta-Analysis
Blood Pressure
Lipids
Mortality
Hydroxymethylglutaryl-CoA Reductase Inhibitors
7 Citations (Scopus)

Development of an Australian cardiovascular disease mortality risk score using multiple imputation and recalibration from national statistics

Backholer, K., Hirakawa, Y., Tonkin, A., Giles, G., Magliano, D. J., Colagiuri, S., Harris, M., Mitchell, P., Nelson, M., Shaw, J. E., Simmons, D., Simons, L., Taylor, A., Harding, J., Gopinath, B. & Woodward, M., Jan 6 2017, In : BMC Cardiovascular Disorders. 17, 1, 17.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Mortality
Blood Pressure
HDL Cholesterol
Smoking
7 Citations (Scopus)

Muscle strength, mobility, quality of life and falls in patients on maintenance haemodialysis: A prospective study

Wang, A. Y., Sherrington, C., Toyama, T., Gallagher, M. P., Cass, A., Hirakawa, Y., Li, Q., Sukkar, L., Snelling, P. & Jardine, M. J., Mar 1 2017, In : Nephrology. 22, 3, p. 220-227 8 p.

Research output: Contribution to journalArticle

Muscle Strength
Renal Dialysis
Maintenance
Quality of Life
Prospective Studies
5 Citations (Scopus)
Chronic Renal Insufficiency
Cardiovascular Diseases
Coronary Disease
Serum
Confidence Intervals
2 Citations (Scopus)

Side effects and tolerability of combination blood pressure lowering according to blood pressure levels: An analysis of the PROGRESS and ADVANCEtrials

Atkins, E. R., Hirakawa, Y., Salam, A., Woodward, M., Cooper, M., Hamet, P., Harrap, S., Lees, K., Liu, L., Mancia, G., Marre, M., Perkovic, V., Poulter, N., Williams, B., Chalmers, J. & Rodgers, A., Jan 1 2017, In : Journal of hypertension. 35, 6, p. 1318-1325 8 p.

Research output: Contribution to journalArticle

Blood Pressure
Hypotension
Therapeutics
Kidney
perindopril drug combination indapamide
3 Citations (Scopus)

The gene-treatment interaction of paraoxonase-1 gene polymorphism and statin therapy on insulin secretion in Japanese patients with type 2 diabetes: Fukuoka diabetes registry

Sumi, A., Nakamura, U., Iwase, M., Fujii, H., Ohkuma, T., Ide, H., Jodai-Kitamura, T., Komorita, Y., Yoshinari, M., Hirakawa, Y., Hirano, A., Kubo, M. & Kitazono, T., Dec 12 2017, In : BMC Medical Genetics. 18, 1, 146.

Research output: Contribution to journalArticle

Aryldialkylphosphatase
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Type 2 Diabetes Mellitus
Registries
Insulin
1 Citation (Scopus)

The ratio of serum eicosapentaenoic acid to arachidonic acid and risk of cancer death in a Japanese community: The Hisayama Study

Nagata, M., Hata, J., Hirakawa, Y., Mukai, N., Yoshida, D., Ohara, T., Kishimoto, H., Kawano, H., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Jan 1 2017, In : Journal of epidemiology. 27, 12, p. 578-583 6 p.

Research output: Contribution to journalArticle

Eicosapentaenoic Acid
Arachidonic Acid
Serum
Neoplasms
Independent Living
6 Citations (Scopus)

White-coat and masked hypertension are associated with albuminuria in a general population: The Hisayama Study

Hata, J., Fukuhara, M., Sakata, S., Arima, H., Hirakawa, Y., Yonemoto, K., Mukai, N., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Nov 1 2017, In : Hypertension Research. 40, 11, p. 937-943 7 p.

Research output: Contribution to journalArticle

Masked Hypertension
White Coat Hypertension
Albuminuria
Hypertension
Population
2016
10 Citations (Scopus)

Admission Heart Rate Predicts Poor Outcomes in Acute Intracerebral Hemorrhage: The Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial Studies

Qiu, M., Sato, S., Zheng, D., Wang, X., Carcel, C., Hirakawa, Y., Sandset, E. C., Delcourt, C., Arima, H., Wang, J., Chalmers, J. & Anderson, C. S., Jun 1 2016, In : Stroke. 47, 6, p. 1479-1485 7 p.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Heart Rate
Blood Pressure
Hematoma
Mortality
16 Citations (Scopus)

Combination of helicobacter pylori antibody and serum pepsinogen as a good predictive tool of gastric cancer incidence: 20-year prospective data from the hisayama study

Ikeda, F., Shikata, K., Hata, J., Fukuhara, M., Hirakawa, Y., Ohara, T., Mukai, N., Nagata, M., Yoshida, D., Yonemoto, K., Esaki, M., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Jan 1 2016, In : Journal of epidemiology. 26, 12, p. 629-636 8 p.

Research output: Contribution to journalArticle

Pepsinogen A
Helicobacter pylori
Stomach Neoplasms
Antibodies
Incidence
7 Citations (Scopus)

Depression but not anxiety predicts recurrent cerebrovascular events

Yu, S., Arima, H., Bertmar, C., Hirakawa, Y., Priglinger, M., Evans, K. & Krause, M., Jul 1 2016, In : Acta Neurologica Scandinavica. 134, 1, p. 29-34 6 p.

Research output: Contribution to journalArticle

Anxiety
Stroke
Depression
Transient Ischemic Attack
Logistic Models
11 Citations (Scopus)

Effects of smoking and its cessation on creatinine- and cystatin C-based estimated glomerular filtration rates and albuminuria in male patients with type 2 diabetes mellitus: The Fukuoka Diabetes Registry

Ohkuma, T., Nakamura, U., Iwase, M., Ide, H., Fujii, H., Jodai, T., Kaizu, S., Kikuchi, Y., Idewaki, Y., Sumi, A., Hirakawa, Y. & Kitazono, T., Oct 1 2016, In : Hypertension Research. 39, 10, p. 744-751 8 p.

Research output: Contribution to journalArticle

Cystatin C
Albuminuria
Smoking Cessation
Glomerular Filtration Rate
Type 2 Diabetes Mellitus
3 Citations (Scopus)

Foveal and Macular Thickness in a Japanese Population: The Hisayama Study

Hashimoto, S., Yasuda, M., Ninomiya, T., Hata, J., Yoshida, D., Tahara-Asakuma, T., Hirakawa, Y., Arakawa, S., Fujiwara, K., Kiyohara, Y. & Ishibashi, T., May 3 2016, In : Ophthalmic Epidemiology. 23, 3, p. 202-208 7 p.

Research output: Contribution to journalArticle

Refractive Errors
Body Height
Smoking
Population
Regression Analysis
24 Citations (Scopus)

Microvascular and macrovascular disease and risk for major peripheral arterial disease in patients with type 2 diabetes

Mohammedi, K., Woodward, M., Hirakawa, Y., Zoungas, S., Williams, B., Lisheng, L., Rodgers, A., Mancia, G., Neal, B., Harrap, S., Marre, M. & Chalmers, J., Oct 1 2016, In : Diabetes care. 39, 10, p. 1796-1803 8 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Type 2 Diabetes Mellitus
perindopril drug combination indapamide
Light Coagulation
Vascular Diseases
11 Citations (Scopus)

Prediction of 10-year vascular risk in patients with diabetes: The AD-ON risk score

on behalf of the ADVANCE Collaborative Group, Mar 1 2016, In : Diabetes, Obesity and Metabolism. 18, 3, p. 289-294 6 p.

Research output: Contribution to journalArticle

Blood Vessels
perindopril drug combination indapamide
Kidney
Gliclazide
Random Allocation
26 Citations (Scopus)

Presentations of major peripheral arterial disease and risk of major outcomes in patients with type 2 diabetes: Results from the ADVANCE-ON study

Mohammedi, K., Woodward, M., Hirakawa, Y., Zoungas, S., Colagiuri, S., Hamet, P., Harrap, S., Poulter, N., Matthews, D. R., Marre, M. & Chalmers, J., Sep 2 2016, In : Cardiovascular Diabetology. 15, 1, 129.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Type 2 Diabetes Mellitus
Amputation
Lower Extremity
perindopril drug combination indapamide
21 Citations (Scopus)

Risks associated with permanent discontinuation of blood pressure-lowering medications in patients with type 2 diabetes

Hirakawa, Y., Arima, H., Webster, R., Zoungas, S., Li, Q., Harrap, S., Lisheng, L., Hamet, P., Mancia, G., Poulter, N., Neal, B., Williams, B., Rogers, A., Woodward, M. & Chalmers, J., Apr 1 2016, In : Journal of hypertension. 34, 4, p. 781-787 7 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Blood Pressure
perindopril drug combination indapamide
Placebos
Indapamide
10 Citations (Scopus)

Serum Angiopoietin-Like Protein 2 Is a Novel Risk Factor for Cardiovascular Disease in the Community

Hata, J., Mukai, N., Nagata, M., Ohara, T., Yoshida, D., Kishimoto, H., Shibata, M., Hirakawa, Y., Endo, M., Ago, T., Kitazono, T., Oike, Y., Kiyohara, Y. & Ninomiya, T., Aug 1 2016, In : Arteriosclerosis, thrombosis, and vascular biology. 36, 8, p. 1686-1691 6 p.

Research output: Contribution to journalArticle

Angiopoietins
Cardiovascular Diseases
Serum
Proteins
Confidence Intervals
22 Citations (Scopus)

Serum uric acid as a risk factor for chronic kidney disease in a Japanese community-the hisayama study

Takae, K., Nagata, M., Hata, J., Mukai, N., Hirakawa, Y., Yoshida, D., Kishimoto, H., Tsuruya, K., Kitazono, T., Kiyohara, Y. & Ninomiya, T., Jan 1 2016, In : Circulation Journal. 80, 8, p. 1857-1862 6 p.

Research output: Contribution to journalArticle

Uric Acid
Chronic Renal Insufficiency
Albuminuria
Serum
Kidney