Research Output per year
Research Output 1997 2019
- 1 - 50 out of 52 results
- Publication Year, Title (descending)
2019
Are the 2016 EULAR/ACR/PRINTO classification criteria for macrophage activation syndrome applicable to patients with adult-onset Still’s disease?
Tada, Y., Inokuchi, S., Maruyama, A., Suematsu, R., Sakai, M., Sadanaga, Y., Ono, N., Arinobu, Y. & Koarada, S., Jan 18 2019, In : Rheumatology International. 39, 1, p. 97-104 8 p.Research output: Contribution to journal › Article
Macrophage Activation Syndrome
Adult-Onset Still's Disease
Juvenile Arthritis
Sensitivity and Specificity
Triglycerides
CD34-selected versus unmanipulated autologous haematopoietic stem cell transplantation in the treatment of severe systemic sclerosis: A post hoc analysis of a phase I/II clinical trial conducted in Japan
Ayano, M., Tsukamoto, H., Mitoma, H., kimoto, Y., Akahoshi, M., Arinobu, Y., Miyamoto, T., Horiuchi, T., Niiro, H., Nagafuji, K., Harada, M. & Akashi, K., Jan 22 2019, In : Arthritis Research and Therapy. 21, 1, 30.Research output: Contribution to journal › Article
Phase II Clinical Trials
Clinical Trials, Phase I
Systemic Scleroderma
Hematopoietic Stem Cell Transplantation
Japan
Serum levels of fibroblast growth factor-2 distinguish Takayasu arteritis from giant cell arteritis independent of age at diagnosis
Fukui, S., Kuwahara-Takaki, A., Ono, N., Sato, S., Koga, T., Kawashiri, S. Y., Iwanaga, N., Iwamoto, N., Ichinose, K., Tamai, M., Nakamura, H., Origuchi, T., Migita, K., Arinobu, Y., Niiro, H., Tada, Y., Akashi, K., Maeda, T. & Kawakami, A., Dec 1 2019, In : Scientific reports. 9, 1, 688.Research output: Contribution to journal › Article
Takayasu Arteritis
Giant Cell Arteritis
Fibroblast Growth Factor 2
Granulocyte-Macrophage Colony-Stimulating Factor
Serum
2018
1
Citation
(Scopus)
Effects of tumor necrosis factor inhibitors and tocilizumab on the glycosylated hemoglobin levels in patients with rheumatoid arthritis; an observational study
Otsuka, Y., Kiyohara, C., Kashiwado, Y., Sawabe, T., Nagano, S., kimoto, Y., Ayano, M., Mitoma, H., Akahoshi, M., Arinobu, Y., Niiro, H., Akashi, K. & Horiuchi, T., Apr 1 2018, In : PloS one. 13, 4, e0196368.Research output: Contribution to journal › Article
glycohemoglobin
rheumatoid arthritis
tumor necrosis factors
Glycosylated Hemoglobin A
observational studies
Notch1 expression is regulated at the post-transcriptional level by the 3′ untranslated region in hematopoietic stem cell development
Mizuno, S., Iino, T., Ozawa, H., Arinobu, Y., Jeong, Y. & Akashi, K., Mar 1 2018, In : International Journal of Hematology. 107, 3, p. 311-319 9 p.Research output: Contribution to journal › Article
3' Untranslated Regions
Hematopoietic Stem Cells
Hematopoiesis
Messenger RNA
Essential Genes
2
Citations
(Scopus)
Ultrasonographic Efficacy of Biologic and Targeted Synthetic Disease-Modifying Antirheumatic Drug Therapy in Rheumatoid Arthritis From a Multicenter Rheumatoid Arthritis Ultrasound Prospective Cohort in Japan
Nishino, A., Kawashiri, S. Y., Koga, T., Iwamoto, N., Ichinose, K., Tamai, M., Nakamura, H., Origuchi, T., Ueki, Y., Yoshitama, T., Eiraku, N., Matsuoka, N., Okada, A., Fujikawa, K., Hamada, H., Tsuru, T., Nagano, S., Arinobu, Y., Hidaka, T. & Kawakami, A., Dec 1 2018, In : Arthritis Care and Research. 70, 12, p. 1719-1726 8 p.Research output: Contribution to journal › Article
Antirheumatic Agents
Rheumatoid Arthritis
Japan
Drug Therapy
Logistic Models
2017
9
Citations
(Scopus)
Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytes
Tsuzuki, H., Arinobu, Y., Miyawaki, K., Takaki, A., Ota, S. I., Ota, Y., Mitoma, H., Akahoshi, M., Mori, Y., Iwasaki, H., Niiro, H., Tsukamoto, H. & Akashi, K., Jan 1 2017, In : Immunology. 150, 1, p. 64-73 10 p.Research output: Contribution to journal › Article
Granulocytes
Hypersensitivity
Eosinophils
Basophils
Mast Cells
3
Citations
(Scopus)
Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head
Sakamoto, Y., Yamamoto, T., Sugano, N., Takahashi, D., Watanabe, T., Atsumi, T., Nakamura, J., Hasegawa, Y., Akashi, K., Narita, I., Miyamoto, T., Takeuchi, T., Ikari, K., Amano, K., Fujie, A., Kubo, T., Tada, Y., Kaneuji, A., Nakamura, H., Miyamura, T. & 70 others, Dec 1 2017, In : Scientific reports. 7, 1, 15035.Research output: Contribution to journal › Article
Osteonecrosis
Genome-Wide Association Study
Thigh
Hip Joint
Drinking
9
Citations
(Scopus)
Identification of unipotent megakaryocyte progenitors in human hematopoiesis
Miyawaki, K., Iwasaki, H., Jiromaru, T., Kusumoto, H., Yurino, A., Sugio, T., Uehara, Y., Odawara, J., Daitoku, S., Kunisaki, Y., Mori, Y., Arinobu, Y., Tsuzuki, H., Kikushige, Y., Iino, T., Kato, K., Takenaka, K., Miyamoto, T., Maeda, T. & Akashi, K., Jun 22 2017, In : Blood. 129, 25, p. 3332-3343 12 p.Research output: Contribution to journal › Article
Megakaryocyte Progenitor Cells
Megakaryocytes
Hematopoiesis
Cells
Janus Kinase 2
2016
9
Citations
(Scopus)
Generation mechanism of RANKL + effector memory B cells: Relevance to the pathogenesis of rheumatoid arthritis
Ota, Y., Niiro, H., Ota, S. I., Ueki, N., Tsuzuki, H., Nakayama, T., Mishima, K., Higashioka, K., Jabbarzadeh-Tabrizi, S., Mitoma, H., Akahoshi, M., Arinobu, Y., Kukita, A., Yamada, H., Tsukamoto, H. & Akashi, K., Mar 16 2016, In : Arthritis Research and Therapy. 18, 1, 67.Research output: Contribution to journal › Article
B-Lymphocyte Subsets
Rheumatoid Arthritis
B-Lymphocytes
Interferons
Osteoprotegerin
2015
11
Citations
(Scopus)
A case of marginal zone B cell lymphoma mimicking IgG4-related dacryoadenitis and sialoadenitis
Ohta, M., Moriyama, M., Goto, Y., Kawano, S., Tanaka, A., maehara, T., Furukawa, S., Jun-Nosuke, H., Kiyoshima, T., Shimizu, M., Arinobu, Y. & Nakamura, S., Feb 21 2015, In : World Journal of Surgical Oncology. 13, 1, 67.Research output: Contribution to journal › Article
Dacryocystitis
Sialadenitis
Marginal Zone B-Cell Lymphoma
Immunoglobulin G
Lymphoma
23
Citations
(Scopus)
CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: Redefinition of murine common myeloid progenitor
Miyawaki, K., Arinobu, Y., Iwasaki, H., Kohno, K., Tsuzuki, H., Iino, T., Shima, T., Kikushige, Y., Takenaka, K., Miyamoto, T. & Akashi, K., Mar 1 2015, In : STEM CELLS. 33, 3, p. 976-987 12 p.Research output: Contribution to journal › Article
Myeloid Progenitor Cells
Hematopoiesis
Myelopoiesis
Cytidine Monophosphate
Population
10
Citations
(Scopus)
Increased CD226 expression on CD8+ T cells is associated with upregulated cytokine production and endothelial cell injury in patients with systemic sclerosis
Ayano, M., Tsukamoto, H., Kohno, K., Ueda, N., Tanaka, A., Mitoma, H., Akahoshi, M., Arinobu, Y., Niiro, H., Horiuchi, T. & Akashi, K., Jan 1 2015, In : Journal of Immunology. 195, 3, p. 892-900 9 p.Research output: Contribution to journal › Article
Systemic Scleroderma
Endothelial Cells
Cytokines
T-Lymphocytes
Wounds and Injuries
6
Citations
(Scopus)
Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis
Tanaka, A., Tsukamoto, H., Mitoma, H., Kiyohara, C., Ueda, N., Ayano, M., Ohta, S. I., kimoto, Y., Akahoshi, M., Arinobu, Y., Niiro, H., Tada, Y., Horiuchi, T. & Akashi, K., Dec 14 2015, In : Arthritis Research and Therapy. 17, 1, 27.Research output: Contribution to journal › Article
Dermatomyositis
Interstitial Lung Diseases
Serum
Polymyositis
Protein S
2013
32
Citations
(Scopus)
The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factorα
Ueda, N., Tsukamoto, H., Mitoma, H., Ayano, M., Tanaka, A., Ohta, S. I., Inoue, Y., Arinobu, Y., Niiro, H., Akashi, K. & Horiuchi, T., May 1 2013, In : Inflammatory Bowel Diseases. 19, 6, p. 1224-1231 8 p.Research output: Contribution to journal › Article
Antibody-Dependent Cell Cytotoxicity
Tumor Necrosis Factor-alpha
Crohn Disease
Jurkat Cells
Tumor Necrosis Factor Receptors
2012
11
Citations
(Scopus)
CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells
Niiro, H., Jabbarzadeh-Tabrizi, S., Kikushige, Y., Shima, T., Noda, K., Ota, S. I., Tsuzuki, H., Inoue, Y., Arinobu, Y., Iwasaki, H., Shimoda, S., Baba, E., Tsukamoto, H., Horiuchi, T., Taniyama, T. & Akashi, K., Mar 8 2012, In : Blood. 119, 10, p. 2263-2273 11 p.Research output: Contribution to journal › Article
Antigen Receptors
Lymphoma
B-Lymphocytes
Cells
Phosphorylation
21
Citations
(Scopus)
Hereditary angioedema in Japan: Genetic analysis of 13 unrelated cases
Yamamoto, T., Horiuchi, T., Miyahara, H., Yoshizawa, S., Maehara, J., Shono, E., Takamura, K., MacHida, H., Tsujioka, K., Kaneko, T., Uemura, N., Suzawa, K., Inagaki, N., Umegaki, N., Kasamatsu, Y., Hara, A., Arinobu, Y., Inoue, Y., Niiro, H., Kashiwagai, Y. & 4 others, Jan 1 2012, In : American Journal of the Medical Sciences. 343, 3, p. 210-214 5 p.Research output: Contribution to journal › Article
Hereditary Angioedemas
Japan
Mutation
Frameshift Mutation
Missense Mutation
38
Citations
(Scopus)
Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity
Tanaka, A., Tsukamoto, H., Mitoma, H., Kiyohara, C., Ueda, N., Ayano, M., Ohta, S. I., Inoue, Y., Arinobu, Y., Niiro, H., Horiuchi, T. & Akashi, K., Nov 11 2012, In : Arthritis Research and Therapy. 14, 6, R244.Research output: Contribution to journal › Article
Systemic Lupus Erythematosus
Serum
Toll-Like Receptor 9
Interleukin-6
Blood Cells
2011
[Myeloid lineage commitment from the hematopoietic stem cell].
Arinobu, Y. & Akashi, K., Jul 2011, In : Japanese Journal of Allergology. 60, 7, p. 817-822 6 p.Research output: Contribution to journal › Review article
Myeloid Cells
Hematopoietic Stem Cells
Cell Differentiation
31
Citations
(Scopus)
Analysis of immune reconstitution after autologous CD34 + stem/progenitor cell transplantation for systemic sclerosis: Predominant reconstitution of Th1 CD4 + t cells
Tsukamoto, H., Nagafuji, K., Horiuchi, T., Mitoma, H., Niiro, H., Arinobu, Y., Inoue, Y., To, K., Miyamoto, T., Iwasaki, H., Teshima, T., Harada, M. & Akashi, K., May 1 2011, In : Rheumatology. 50, 5, p. 944-952 9 p., keq414.Research output: Contribution to journal › Article
Systemic Scleroderma
Hematopoietic Stem Cell Transplantation
Stem Cell Transplantation
Stem Cells
Sclerosis
1
Citation
(Scopus)
Myeloid lineage commitment from the hematopoietic stem cell
Arinobu, Y. & Akashi, K., Dec 1 2011, In : Japanese Journal of Allergology. 60, 7, p. 817-822 6 p.Research output: Contribution to journal › Article
Hematopoietic Stem Cells
Transcription Factors
2010
37
Citations
(Scopus)
Single pancreatic beta cells co-express multiple islet hormone genes in mice
Katsuta, H., Akashi, T., Katsuta, R., Nagaya, M., Kim, D., Arinobu, Y., Hara, M., Bonner-Weir, S., Sharma, A. J., Akashi, K. & Weir, G. C., Jan 1 2010, In : Diabetologia. 53, 1, p. 128-138 11 p.Research output: Contribution to journal › Article
Insulin-Secreting Cells
Hormones
Green Fluorescent Proteins
Genes
Insulin
10
Citations
(Scopus)
Wegener's granulomatosis detected initially by integrated 18F-fluorodeoxyglucose positron emission tomography/computed tomography
Ueda, N., Inoue, Y., Himeji, D., Shimao, Y., Oryoji, K., Mitoma, H., Arinobu, Y., Niiro, H., Tsukamoto, H., Horiuchi, T., Ueda, A. & Akashi, K., Apr 1 2010, In : Modern Rheumatology. 20, 2, p. 205-209 5 p.Research output: Contribution to journal › Article
Granulomatosis with Polyangiitis
Fluorodeoxyglucose F18
Early Diagnosis
Mucous Membrane
Biopsy
2009
46
Citations
(Scopus)
Origin of basophils and mast cells
Arinobu, Y., Iwasaki, H. & Akashi, K., Jan 1 2009, In : Allergology International. 58, 1, p. 21-28 8 p.Research output: Contribution to journal › Review article
Basophils
Mast Cells
Cell Lineage
Hematology
Hematopoietic Stem Cells
2008
13
Citations
(Scopus)
Acquired hemophilia in a patient with systemic lupus erythematosus: A case report and literature review
Akahoshi, M., Aizawa, K., Nagano, S., Inoue, H., Sadanaga, A., Arinobu, Y., Niiro, H. & Nakashima, H., Jun 13 2008, In : Modern Rheumatology. 18, 5, p. 511-515 5 p.Research output: Contribution to journal › Article
Factor VIII
Hemophilia A
Systemic Lupus Erythematosus
Ecchymosis
Partial Thromboplastin Time
59
Citations
(Scopus)
Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage
Cantor, A. B., Iwasaki, H., Arinobu, Y., Moran, T. B., Shigematsu, H., Sullivan, M. R., Akashi, K. & Orkin, S. H., Mar 17 2008, In : Journal of Experimental Medicine. 205, 3, p. 611-624 14 p.Research output: Contribution to journal › Article
GATA Transcription Factors
Cell Lineage
Mast Cells
Down-Regulation
Gene Regulatory Networks
50
Citations
(Scopus)
CD4 T-cell autoreactivity to the mitochondrial autoantigen PDC-E2 in AMA-negative primary biliary cirrhosis
Shimoda, S., Miyakawa, H., Nakamura, M., Ishibashi, H., Kikuchi, K., Kita, H., Niiro, H., Arinobu, Y., Ono, N., Mackay, I. R., Gershwin, M. E. & Akashi, K., Sep 1 2008, In : Journal of Autoimmunity. 31, 2, p. 110-115 6 p.Research output: Contribution to journal › Article
Biliary Liver Cirrhosis
Anti-Idiotypic Antibodies
T-Lymphocytes
Interleukin-10
T-Lymphocyte Epitopes
2007
31
Citations
(Scopus)
Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue
Alcaide, P., Jones, T. G., Lord, G. M., Glimcher, L. H., Hallgren, J., Arinobu, Y., Akashi, K., Paterson, A. M., Gurish, M. A. & Luscinskas, F. W., Feb 1 2007, In : Journal of Experimental Medicine. 204, 2, p. 431-439 9 p.Research output: Contribution to journal › Article
Mast Cells
Dendritic Cells
Mucous Membrane
Vascular Cell Adhesion Molecule-1
Bone Marrow
193
Citations
(Scopus)
Reciprocal Activation of GATA-1 and PU.1 Marks Initial Specification of Hematopoietic Stem Cells into Myeloerythroid and Myelolymphoid Lineages
Arinobu, Y., Mizuno, S. I., Jeong, Y., Shigematsu, H., Iino, T., Iwasaki, H., Graf, T., Mayfield, R., Chan, S., Kastner, P. & Akashi, K., Oct 11 2007, In : Cell stem cell. 1, 4, p. 416-427 12 p.Research output: Contribution to journal › Article
Hematopoietic Stem Cells
Cytidine Monophosphate
Lymphoid Progenitor Cells
Lymphocytes
Population
2006
191
Citations
(Scopus)
The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages
Iwasaki, H., Mizuno, S. I., Arinobu, Y., Ozawa, H., Mori, Y., Shigematsu, H., Takatsu, K., Tenen, D. G. & Akashi, K., Nov 1 2006, In : Genes and Development. 20, 21, p. 3010-3021 12 p.Research output: Contribution to journal › Article
CCAAT-Enhancer-Binding Proteins
Granulocyte Precursor Cells
Transcription Factors
Monocytes
Basophils
2005
209
Citations
(Scopus)
Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis
Arinobu, Y., Iwasaki, H., Gurish, M. F., Mizuno, S. I., Shigematsu, H., Ozawa, H., Tenen, D. G., Austen, K. F. & Akashi, K., Dec 13 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 50, p. 18105-18110 6 p.Research output: Contribution to journal › Article
Basophils
Hematopoiesis
Cell Lineage
Mast Cells
CCAAT-Enhancer-Binding Proteins
247
Citations
(Scopus)
Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation
Iwasaki, H., Somoza, C., Shigematsu, H., Duprez, E. A., Iwasaki-Arai, J., Mizuno, S., Arinobu, Y., Geary, K., Zhang, P., Dayaram, T., Fenyus, M. L., Elf, S., Chan, S., Kastner, P., Huettner, C. S., Murray, R., Tenen, D. G. & Akashi, K., Sep 1 2005, In : Blood. 106, 5, p. 1590-1600 11 p.Research output: Contribution to journal › Article
Hematopoietic Stem Cells
Stem cells
Cell Differentiation
Maintenance
B-Lymphocytes
124
Citations
(Scopus)
Identification of eosinophil lineage-committed progenitors in the murine bone marrow
Iwasaki, H., Mizuno, S. I., Mayfield, R., Shigematsu, H., Arinobu, Y., Seed, B., Gurish, M. F., Takatsu, K. & Akashi, K., Jun 20 2005, In : Journal of Experimental Medicine. 201, 12, p. 1891-1897 7 p.Research output: Contribution to journal › Article
Eosinophils
Bone Marrow
Monocytes
Granulocyte Precursor Cells
Mast Cells
17
Citations
(Scopus)
TEF, an antiapoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by down-regulating expression of the common β chain of cytokine receptors
Inukai, T., Inaba, T., Dang, J., Kuribara, R., Ozawa, K., Miyajima, A., Wu, W., Look, A. T., Arinobu, Y., Iwasaki, H., Akashi, K., Kagami, K., Goi, K., Sugita, K. & Nakazawa, S., Jun 1 2005, In : Blood. 105, 11, p. 4437-4444 8 p.Research output: Contribution to journal › Article
Basic-Leucine Zipper Transcription Factors
Thyrotrophs
Cytokine Receptors
Cell growth
Leukemia
2004
4
Citations
(Scopus)
A case of Legionella pneumonia complicated with acute respiratory distress syndrome treated with methylprednisolone and sivelestat sodium in combination with intravenous erythromycin and ciprofloxacin
Oguma, A., Kojima, T., Himeji, D., Arinobu, Y., Kikuchi, I. & Ueda, A., Jan 1 2004, In : Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society. 42, 11, p. 956-960 5 p.Research output: Contribution to journal › Article
Legionella
Adult Respiratory Distress Syndrome
Methylprednisolone
Erythromycin
Ciprofloxacin
28
Citations
(Scopus)
Novel Regulatory Mechanisms of CD40-Induced Prostanoid Synthesis by IL-4 and IL-10 in Human Monocytes
Inoue, Y., Otsuka, T., Niiro, H., Nagano, S., Arinobu, Y., Ogami, E., Akahoshi, M., Miyake, K., Ninomiya, I., Shimizu, S., Nakashima, H. & Harada, M., Feb 15 2004, In : Journal of Immunology. 172, 4, p. 2147-2154 8 p.Research output: Contribution to journal › Article
Interleukin-4
Interleukin-10
Prostaglandins
Monocytes
Phosphotransferases
2002
44
Citations
(Scopus)
Molecular mechanisms of lipopolysaccharide-induced cyclooxygenase-2 expression in human neutrophils: Involvement of the mitogen-activated protein kinase pathway and regulation by anti-inflammatory cytokines
Nagano, S., Otsuka, T., Niiro, H., Yamaoka, K., Arinobu, Y., Ogami, E., Akahoshi, M., Inoue, Y., Miyake, K., Nakashima, H., Niho, Y. & Harada, M., Aug 7 2002, In : International Immunology. 14, 7, p. 733-740 8 p.Research output: Contribution to journal › Article
Cyclooxygenase 2
Mitogen-Activated Protein Kinases
Lipopolysaccharides
Neutrophils
Anti-Inflammatory Agents
2001
105
Citations
(Scopus)
Association of tumor necrosis factor receptor type II polymorphism 196R with systemic lupus erythematosus in the Japanese molecular and functional analysis
Morita, C., Horiuchi, T., Tsukamoto, H., Hatta, N., Kikuchi, Y., Arinobu, Y., Otsuka, T., Sawabe, T., Harashima, S. I., Nagasawa, K. & Niho, Y., Dec 1 2001, In : Arthritis and Rheumatism. 44, 12, p. 2819-2827 9 p.Research output: Contribution to journal › Article
Receptors, Tumor Necrosis Factor, Type II
Tumor Necrosis Factor Receptors
Systemic Lupus Erythematosus
Exons
HeLa Cells
2000
9
Citations
(Scopus)
Augmentation of signal transducer and activation of transcription (STAT)6 and STAT3 expression in stimulated B and T cells
Arinobu, Y., Sugimoto, R., Akaiwa, M., Arima, K., Otsuka, T., Hamasaki, N. & Izuhara, K., Oct 22 2000, In : Biochemical and Biophysical Research Communications. 277, 2, p. 317-324 8 p.Research output: Contribution to journal › Article
T-cells
Interleukin-13
Transcription
Transducers
Interleukin-4
368
Citations
(Scopus)
Genetic variants of IL-13 signalling and human asthma and atopy
Heinzmann, A., Mao, X. Q., Akaiwa, M., Kreomer, R. T., Gao, P. S., Ohshima, K., Umeshita, R., Abe, Y., Braun, S., Yamashita, T., Roberts, M. H., Sugimoto, R., Arima, K., Arinobu, Y., Yu, B., Kruse, S., Enomoto, T., Dake, Y., Kawai, M., Shimazu, S. & 12 others, Mar 1 2000, In : Human Molecular Genetics. 9, 4, p. 549-559 11 p.Research output: Contribution to journal › Article
Interleukin-13
Asthma
Immunoglobulin E
Smooth Muscle
Chromosomes
72
Citations
(Scopus)
Variants of STAT6 (signal transducer and activator of transcription 6) in atopic asthma
Gao, P. S., Mao, X. Q., Roberts, M. H., Arinobu, Y., Akaiwa, M., Enomoto, T., Dake, Y., Kawai, M., Sasaki, S., Hamasaki, N., Izuhara, K., Shirakawa, T. & Hopkin, J. M., May 25 2000, In : Journal of medical genetics. 37, 5, p. 380-382 3 p.Research output: Contribution to journal › Letter
1999
65
Citations
(Scopus)
Antagonistic effects of an alternative splice variant of human IL-4, IL- 4δ2, on IL-4 activities in human monocytes and B cells
Arinobu, Y., Atamas, S. P., Otsuka, T., Niiro, H., Yamaoka, K., Mitsuyasu, H., Niho, Y., Hamasaki, N., White, B. & Izuhara, K., Feb 1 1999, In : Cellular Immunology. 191, 2, p. 161-167 7 p.Research output: Contribution to journal › Article
Human Activities
Interleukin-4
Monocytes
B-Lymphocytes
Cytokines
6
Citations
(Scopus)
Association of the interleukin-4 receptor α chain with p47(phox), an activator of the phagocyte NADPH oxidase in B cells
Izuhara, K., Arinobu, Y., Sumimoto, H., Nunoi, H., Takeya, R., Higuchi, K., Takeshige, K., Hamasaki, N. & Harada, N., Jan 1 1999, In : Molecular Immunology. 36, 1, p. 45-52 8 p.Research output: Contribution to journal › Article
Interleukin-4 Receptors
NADPH Oxidase
Interleukins
Phagocytes
B-Lymphocytes
159
Citations
(Scopus)
Cutting edge: Dominant effect of Ile50Val variant of the human IL-4 receptor α-chain in IgE synthesis
Mitsuyasu, H., Yanagihara, Y., Mao, X. Q., Gao, P. S., Arinobu, Y., Ihara, K., Takabayashi, A., Hara, T., Enomoto, T., Sasaki, S., Kawai, M., Hamasaki, N., Shirakawa, T., Hopkin, J. M. & Izuhara, K., Feb 1 1999, In : Journal of Immunology. 162, 3, p. 1227-1231 5 p.Research output: Contribution to journal › Article
Interleukin-4 Receptors
Interleukin-4
Immunoglobulin E
Transcriptional Activation
Asthma
16
Citations
(Scopus)
Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus
Nakashima, H., Akahoshi, M., Tanaka, Y., Yamaoka, K., Ogami, E., Nagano, S., Arinobu, Y., Niiro, H., Otsuka, T. & Niho, Y., Jan 1 1999, In : Rheumatology. 38, 11, p. 1142-1144 3 p.Research output: Contribution to journal › Article
Interleukin-10 Receptors
Systemic Lupus Erythematosus
Complementary DNA
Genotype
Genes
223
Citations
(Scopus)
Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus
Akahoshi, M., Nakashima, H., Tanaka, Y., Kohsaka, T., Nagano, S., Ohgami, E., Arinobu, Y., Yamaoka, K., Niiro, H., Shinozaki, M., Hirakata, H., Horiuchi, T., Otsuka, T. & Niho, Y., Aug 1 1999, In : Arthritis and Rheumatism. 42, 8, p. 1644-1648 5 p.Research output: Contribution to journal › Article
Th1-Th2 Balance
Helper-Inducer T-Lymphocytes
Systemic Lupus Erythematosus
Th2 Cells
Lupus Nephritis
53
Citations
(Scopus)
The combination of polymorphisms within interferon-γ receptor I and receptor 2 associated with the risk of systemic lupus erythematosus
Nakashima, H., Inoue, H., Akahoshi, M., Tanaka, Y., Yamaoka, K., Ogami, E., Nagano, S., Arinobu, Y., Niiro, H., Otsuka, T. & Niho, Y., Jun 18 1999, In : FEBS Letters. 453, 1-2, p. 187-190 4 p.Research output: Contribution to journal › Article
Interferon Receptors
Polymorphism
Systemic Lupus Erythematosus
Amino Acids
Genotype
2
Citations
(Scopus)
Two polymorphisms within interleukin-3 (hlL3) gene detected by mismatch PCR/RFLP
Nakashima, H., Otsuka, T., Ohba, Y., Akahoshi, M., Nagano, S., Ogami, E., Arinobu, Y., Miyake, K., Inoue, Y., Niiro, H., Kaji, Y. & Niho, Y., Jan 1 1999, In : Genes and Immunity. 1, 2, p. 156-158 3 p.Research output: Contribution to journal › Article
Interleukin-3
Nucleic Acid Databases
Restriction Fragment Length Polymorphisms
Thymine
Cytosine
1998
46
Citations
(Scopus)
Activation of STAT5 by lipopolysaccharide through granulocyte-macrophage colony-stimulating factor production in human monocytes
Yamaoka, K., Otsuka, T., Niiro, H., Arinobu, Y., Niho, Y., Hamasaki, N. & Izuhara, K., Jan 15 1998, In : Journal of Immunology. 160, 2, p. 838-845 8 p.Research output: Contribution to journal › Article
Granulocyte-Macrophage Colony-Stimulating Factor
Lipopolysaccharides
Monocytes
Prostaglandin-Endoperoxide Synthases
Granulocytes
314
Citations
(Scopus)
Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma.
Mitsuyasu, H., Izuhara, K., Mao, X. Q., Gao, P. S., Arinobu, Y., Enomoto, T., Kawai, M., Sasaki, S., Dake, Y., Hamasaki, N., Shirakawa, T. & Hopkin, J. M., Jan 1 1998, In : Nature genetics. 19, 2, p. 119-120 2 p.Research output: Contribution to journal › Letter