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Research Output 1987 2019

2014
25 Citations (Scopus)

Distinct composition of the oral indigenous microbiota in South Korean and Japanese adults

Takeshita, T., Matsuo, K., Furuta, M., Shibata, Y., Fukami, K., Shimazaki, Y., Akifusa, S., Han, D. H., Kim, H. D., Yokoyama, T., Ninomiya, T., Kiyohara, Y. & Yamashita, Y., Nov 11 2014, In : Scientific reports. 4, 6990.

Research output: Contribution to journalArticle

Microbiota
Veillonella
Prevotella
Haemophilus
Neisseria
11 Citations (Scopus)

Factors associated with dry mouth in dependent Japanese elderly

Kakudate, N., Muramatsu, T., Endoh, M., Satomura, K., Koseki, T., Sato, Y., Ito, K., Ogasawara, T., Nakamura, S., Kishimoto, E., Kashiwazaki, H., Yamashita, Y., Uchiyama, K., Nishihara, T., Kiyohara, Y. & Kakinoki, Y., Mar 1 2014, In : Gerodontology. 31, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

Mouth
Diuretics
Antidepressive Agents
Mouth Breathing
Oral Health
31 Citations (Scopus)

Identification of the microbiota in carious dentin lesions using 16S rRNA gene sequencing

Obata, J., Takeshita, T., Shibata, Y., Yamanaka, W., Unemori, M., Akamine, A. & Yamashita, Y., Aug 1 2014, In : PloS one. 9, 8, e103712.

Research output: Contribution to journalArticle

Atopobium
Microbiota
Dental Caries
Propionibacterium
rRNA Genes
9 Citations (Scopus)

Molecular analysis of fungal populations in patients with oral candidiasis using internal transcribed spacer region

Ieda, S., Moriyama, M., Takashita, T., maehara, T., Imabayashi, Y., Shinozaki, S., Tanaka, A., Jun-Nosuke, H., Furukawa, S., Ohta, M., Yamashita, Y. & Nakamura, S., Jun 30 2014, In : PloS one. 9, 6, e101156.

Research output: Contribution to journalArticle

Oral Candidiasis
candidiasis
Fungi
internal transcribed spacers
mouth
37 Citations (Scopus)

Nutritional status and dysphagia risk among community-dwelling frail older adults

Takeuchi, K., Aida, J., Ito, K., Furuta, M., Yamashita, Y. & Osaka, K., Jan 1 2014, In : Journal of Nutrition, Health and Aging. 18, 4, p. 352-357 6 p.

Research output: Contribution to journalArticle

Independent Living
Frail Elderly
Deglutition Disorders
Nutritional Status
Malnutrition
4 Citations (Scopus)

Supervised machine learning-based classification of oral malodor based on the microbiota in saliva samples

Nakano, Y., Takeshita, T., Kamio, N., Shiota, S., Shibata, Y., Suzuki, N., Yoneda, M., Hirofuji, T. & Yamashita, Y., Feb 1 2014, In : Artificial Intelligence in Medicine. 60, 2, p. 97-101 5 p.

Research output: Contribution to journalArticle

Microbiota
Saliva
Learning systems
Decision Trees
Support vector machines
2013

Adiponectin and Macrophage

Akifusa, S. & Yamashita, Y., 2013, Nova Science Publishers, Inc. 21 p.

Research output: Book/ReportBook

Adiponectin
Macrophages
Adipokines
Adipose Tissue
Adipocytes
27 Citations (Scopus)

Bacterial adhesion affinities of various implant abutment materials

Yamane, K., Ayukawa, Y., Takeshita, T., Furuhashi, A., Yamashita, Y. & Koyano, K., Dec 2013, In : Clinical Oral Implants Research. 24, 12, p. 1310-1315 6 p.

Research output: Contribution to journalArticle

Bacterial Adhesion
Platinum
Gold Alloys
Bacterial Structures
Splints
3 Citations (Scopus)

Continual gram-negative bacterial challenge accelerates stroke onset in stroke-prone spontaneously hypertensive rats

Kawato, T., Tanaka, H., Tabuchi, M., Ooshima, K., Nakai, K., Yamashita, Y. & Maeno, M., Jan 7 2013, In : Clinical and Experimental Hypertension. 35, 1, p. 28-34 7 p.

Research output: Contribution to journalArticle

Inbred SHR Rats
Stroke
Lipopolysaccharides
Piloerection
Hyperkinesis
23 Citations (Scopus)

Gender differences in the association between metabolic syndrome and periodontal disease: The Hisayama Study

Furuta, M., Shimazaki, Y., Takeshita, T., Shibata, Y., Akifusa, S., Eshima, N., Kiyohara, Y., Ninomiya, T., Hirakawa, Y., Mukai, N., Nagata, M. & Yamashita, Y., Aug 1 2013, In : Journal of Clinical Periodontology. 40, 8, p. 743-752 10 p.

Research output: Contribution to journalArticle

Metabolic Diseases
Periodontal Diseases
Structural Models
Logistic Models
Regression Analysis
73 Citations (Scopus)
Aptitude
Oral Health
Deglutition
Home Care Services
Activities of Daily Living
11 Citations (Scopus)

Involvement of the novel two-component nsrrs and lcrrs systems in distinct resistance pathways against nisin a and nukacin isk-1 in streptococcus mutans

Kawada-Matsuo, M., Oogai, Y., Zendo, T., Nagao, J., Shibata, Y., Yamashita, Y., Ogura, Y., Hayashi, T., Sonomoto, K. & Komatsuzawa, H., Aug 1 2013, In : Applied and environmental microbiology. 79, 15, p. 4751-4755 5 p.

Research output: Contribution to journalArticle

Nisin
Streptococcus mutans
nisin
Bacteriocins
bacteriocins

Oral Health and Swallowing Problems

Furuta, M. & Yamashita, Y., Sep 15 2013, In : Current Physical Medicine and Rehabilitation Reports. 1, p. 216-222

Research output: Contribution to journalReview article

Oral Health
Deglutition
Eating
Oral Hygiene
Mastication
3 Citations (Scopus)

Relationship between normal serum creatinine concentration and periodontal disease in japanese middle-aged males

Shimazaki, Y., Kushiyama, M., Murakami, M. & Yamashita, Y., Jan 1 2013, In : Journal of Periodontology. 84, 1, p. 94-99 6 p.

Research output: Contribution to journalArticle

Periodontal Diseases
Creatinine
Serum
Reference Values
Periodontitis
43 Citations (Scopus)

Relationship between nutrition status and dental occlusion in community-dwelling frail elderly people

Kikutani, T., Yoshida, M., Enoki, H., Yamashita, Y., Akifusa, S., Shimazaki, Y., Hirano, H. & Tamura, F., Jan 1 2013, In : Geriatrics and Gerontology International. 13, 1, p. 50-54 5 p.

Research output: Contribution to journalArticle

Dental Occlusion
Independent Living
Frail Elderly
Nutritional Status
Malnutrition
14 Citations (Scopus)

Relationship of periodontal clinical parameters with bacterial composition in human dental plaque

Fujinaka, H., Takeshita, T., Sato, H., Yamamoto, T., Nakamura, J., Hase, T. & Yamashita, Y., Jun 1 2013, In : Archives of Microbiology. 195, 6, p. 371-383 13 p.

Research output: Contribution to journalArticle

Dental Plaque
Bacteria
Chemical analysis
Association reactions
Pathogens
2012

Adiponectin and macrophage

Akifusa, S. & Yamashita, Y., 2012, Adiponectin: Production, Regulation and Roles in Disease. Nova Science Publishers, Inc., p. 38-47 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Adiponectin
Macrophages
Adipokines
Adipose Tissue
Adipocytes
16 Citations (Scopus)

Association of CiaRH with resistance of Streptococcus mutans to antimicrobial peptides in biofilms

Mazda, Y., Kawada-Matsuo, M., Kanbara, K., Oogai, Y., Shibata, Y., Yamashita, Y., Miyawaki, S. & Komatsuzawa, H., Apr 1 2012, In : Molecular Oral Microbiology. 27, 2, p. 124-135 12 p.

Research output: Contribution to journalArticle

Streptococcus mutans
Biofilms
Peptides
Antimicrobial Cationic Peptides
Teichoic Acids
30 Citations (Scopus)

Compositional stability of a salivary bacterial population against supragingival microbiota shift following periodontal therapy

Yamanaka, W., Takeshita, T., Shibata, Y., Matsuo, K., Eshima, N., Yokoyama, T. & Yamashita, Y., Aug 16 2012, In : PloS one. 7, 8, e42806.

Research output: Contribution to journalArticle

Microbiota
therapeutics
Chemical analysis
Population
Biodiversity
31 Citations (Scopus)

Discrimination of the oral microbiota associated with high hydrogen sulfide and methyl mercaptan production

Takeshita, T., Suzuki, N., Nakano, Y., Yasui, M., Yoneda, M., Shimazaki, Y., Hirofuji, T. & Yamashita, Y., Apr 19 2012, In : Scientific reports. 2, 215.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Microbiota
Sulfhydryl Compounds
Mouth
Megasphaera
13 Citations (Scopus)

Effects of oil drops containing Lactobacillus salivarius WB21 on periodontal health and oral microbiota producing volatile sulfur compounds

Suzuki, N., Tanabe, K., Takeshita, T., Yoneda, M., Iwamoto, T., Oshiro, S., Yamashita, Y. & Hirofuji, T., Mar 1 2012, In : Journal of Breath Research. 6, 1, 017106.

Research output: Contribution to journalArticle

Sulfur Compounds
Microbiota
Oral Health
Oils
Placebos

Evaluation of salivary microbiota from an ecological perspective

Takeshita, T. & Yamashita, Y., Jan 1 2012, In : Journal of Oral Biosciences. 54, 3, p. 128-131 4 p.

Research output: Contribution to journalReview article

Microbiota
Mouth Diseases
Health
Oral Health
Prevotella
6 Citations (Scopus)

Molecular characterization of fungal populations on the tongue dorsum of institutionalized elderly adults

Li, H., Takeshita, T., Furuta, M., Tomioka, M., Shibata, Y., Shimazaki, Y., Makimura, K. & Yamashita, Y., Nov 1 2012, In : Oral Diseases. 18, 8, p. 771-777 7 p.

Research output: Contribution to journalArticle

Tongue
Fungi
Fever
Candida albicans
Candida
2011
9 Citations (Scopus)

Antimicrobial and antifungal effects of tissue conditioners containing a photocatalyst

Uchimaru, M., Sakai, T., Moroi, R., Shiota, S., Shibata, Y., Deguchi, M., Sakai, H., Yamashita, Y. & Terada, Y., Oct 12 2011, In : dental materials journal. 30, 5, p. 691-699 9 p.

Research output: Contribution to journalArticle

Photocatalysts
Tissue
Microorganisms
Powders
Irradiation
6 Citations (Scopus)

Characterization of MbrC involved in bacitracin resistance in Streptococcus mutans

Kitagawa, N., Shiota, S., Shibata, Y., Takeshita, T. & Yamashita, Y., May 1 2011, In : FEMS microbiology letters. 318, 1, p. 61-67 7 p.

Research output: Contribution to journalLetter

Bacitracin
Streptococcus mutans
Aspartic Acid
Phosphorylation
ATP-Binding Cassette Transporters
5 Citations (Scopus)

Diacylglycerol kinase alpha regulates globular adiponectin-induced reactive oxygen species

Kamio, N., Akifusa, S. & Yamashita, Y., Mar 1 2011, In : Free Radical Research. 45, 3, p. 336-341 6 p.

Research output: Contribution to journalArticle

Diacylglycerol Kinase
Adiponectin
Reactive Oxygen Species
Nitric Oxide
Messenger RNA
10 Citations (Scopus)

Effectiveness of the salivary occult blood test as a screening method for periodontal status

Shimazaki, Y., Akifusa, S., Takeshita, T., Shibata, Y., Doi, Y., Hata, J., Ninomiya, T., Hirakawa, Y., Kiyohara, Y. & Yamashita, Y., Apr 2011, In : Journal of Periodontology. 82, 4, p. 581-587 7 p.

Research output: Contribution to journalArticle

Occult Blood
Hematologic Tests
Tooth
Hemorrhage
Periodontal Diseases
16 Citations (Scopus)

Effect of xylitol gum on the level of oral mutans streptococci of preschoolers: Block-randomised trial

Seki, M., Karakama, F., Kawato, T., Tanaka, H., Saeki, Y. & Yamashita, Y., Oct 1 2011, In : International Dental Journal. 61, 5, p. 274-280 7 p.

Research output: Contribution to journalArticle

Xylitol
Streptococcus mutans
Gingiva
Chewing Gum
Diarrhea
13 Citations (Scopus)

Enteral tube feeding alters the oral indigenous microbiota in elderly adults

Takeshita, T., Yasui, M., Tomioka, M., Nakano, Y., Shimazaki, Y. & Yamashita, Y., Oct 1 2011, In : Applied and environmental microbiology. 77, 19, p. 6739-6745 7 p.

Research output: Contribution to journalArticle

tube feeding
Microbiota
Enteral Nutrition
mouth
polymorphism
2 Citations (Scopus)

Involvement of suppressor of cytokine signaling-1 in globular adiponectin-induced granulocyte colony-stimulating factor in RAW 264 cell

Fujimoto, A., Akifusa, S., Hirofuji, T. & Yamashita, Y., Sep 1 2011, In : Molecular Immunology. 48, 15-16, p. 2052-2058 7 p.

Research output: Contribution to journalArticle

Adiponectin
Granulocyte Colony-Stimulating Factor
Cytokines
MAP Kinase Signaling System
p38 Mitogen-Activated Protein Kinases
2 Citations (Scopus)

Oral flora composition and its connection to oral health

Yamashita, Y. & Takeshita, T., Jan 1 2011, In : journal of oral biosciences. 53, 3, p. 206-212 7 p.

Research output: Contribution to journalReview article

Mouth Diseases
Oral Health
Virulence
Health
Bacteria
6 Citations (Scopus)

Relationship between receiving a workplace oral health examination including oral health instruction and oral health status in the Japanese adult population

Oshikohji, T., Shimazaki, Y., Shinagawa, T., Fukui, N., Akifusa, S., Hirata, Y. & Yamashita, Y., Dec 6 2011, In : Journal of Occupational Health. 53, 3, p. 222-229 8 p.

Research output: Contribution to journalArticle

Oral Diagnosis
Oral Health
Workplace
Health Status
Population
5 Citations (Scopus)

Streptococcus mutans diacylglycerol kinase homologue: A potential target for anti-caries chemotherapy

Shibata, Y., Kawada-Matsuo, M., Shirai, Y., Saito, N., Li, D. & Yamashita, Y., May 1 2011, In : Journal of Medical Microbiology. 60, 5, p. 625-630 6 p.

Research output: Contribution to journalArticle

R 59949
Diacylglycerol Kinase
Streptococcus mutans
Drug Therapy
R 59022
2010

A comprehensive evaluation of the virulence of oral flora

Yamashita, Y. & Takeshita, T., Dec 1 2010, Informatics in Oral Medicine: Advanced Techniques in Clinical and Diagnostic Technologies. IGI Global, p. 251-267 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Mouth Diseases
Virulence
Bacteria
Stomatognathic Diseases
Oral Health
15 Citations (Scopus)

Expression levels of adiponectin receptors and periodontitis

Yamaguchi, N., Hamachi, T., Kamio, N., Akifusa, S., Masuda, K., Nakamura, Y., Nonaka, K., Maeda, K., Hanazawa, S. & Yamashita, Y., Apr 1 2010, In : Journal of Periodontal Research. 45, 2, p. 296-300 5 p.

Research output: Contribution to journalArticle

Adiponectin Receptors
Periodontitis
Periodontal Diseases
Adiponectin
Tumor Necrosis Factor-alpha
26 Citations (Scopus)
Osteogenesis
Transplants
Bone Substitutes
Bone and Bones
Alveolar Process
11 Citations (Scopus)

Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species

Fujimoto, A., Akifusa, S., Kamio, N., Hirofuji, T., Nonaka, K. & Yamashita, Y., Jan 25 2010, In : Free Radical Research. 44, 2, p. 128-134 7 p.

Research output: Contribution to journalArticle

Adiponectin
Sirolimus
Reactive Oxygen Species
Phosphorylation
AMP-Activated Protein Kinases
13 Citations (Scopus)

Involvement of the JAK-STAT Pathway and SOCS3 in the regulation of adiponectin-generated reactive oxygen species in murine macrophage raw 264 cells

Akifusa, S., Kamio, N., Shimazaki, Y., Yamaguchi, N., Nonaka, K. & Yamashita, Y., Oct 15 2010, In : Journal of Cellular Biochemistry. 111, 3, p. 597-606 10 p.

Research output: Contribution to journalArticle

Janus Kinases
Macrophages
Adiponectin
Transcription
Transducers
18 Citations (Scopus)

Microfloral characterization of the tongue coating and associated risk for pneumonia-related health problems in institutionalized older adults

Takeshita, T., Tomioka, M., Shimazaki, Y., Matsuyama, M., Koyano, K., Matsuda, K. & Yamashita, Y., Jan 1 2010, In : Journal of the American Geriatrics Society. 58, 6, p. 1050-1057 8 p.

Research output: Contribution to journalArticle

Tongue
Pneumonia
Restriction Fragment Length Polymorphisms
Health
Regression Analysis
5 Citations (Scopus)
saliva
Monte Carlo method
restriction fragment length polymorphism
polymorphism
prediction
21 Citations (Scopus)

Relationship between obesity and physical fitness and periodontitis

Shimazaki, Y., Egami, Y., Matsubara, T., Koike, G., Akifusa, S., Jingu, S. & Yamashita, Y., Aug 1 2010, In : Journal of periodontology. 81, 8, p. 1124-1131 8 p.

Research output: Contribution to journalArticle

Physical Fitness
Periodontitis
Obesity
Body Mass Index
Periodontal Index
36 Citations (Scopus)

Relationship between oral malodor and the global composition of indigenous bacterial populations in saliva

Takeshita, T., Suzuki, N., Nakano, Y., Shimazaki, Y., Yoneda, M., Hirofuji, T. & Yamashita, Y., May 1 2010, In : Applied and environmental microbiology. 76, 9, p. 2806-2814 9 p.

Research output: Contribution to journalArticle

halitosis
saliva
Saliva
Population Groups
Restriction Fragment Length Polymorphisms
14 Citations (Scopus)

The inhibitory effects of mushroom extracts on sucrose-dependent oral biofilm formation

Yano, A., Kikuchi, S., Yamashita, Y., Sakamoto, Y., Nakagawa, Y. & Yoshida, Y., Mar 1 2010, In : Applied Microbiology and Biotechnology. 86, 2, p. 615-623 9 p.

Research output: Contribution to journalArticle

Agaricales
Biofilms
Streptococcus mutans
Glucans
Streptococcus sobrinus
2009
2 Citations (Scopus)

A novel modification of a bone repositioning device and a new technique for reestablishing facial contours after mandibular resection surgery

Tominaga, K., Yoshioka, I., Yamashita, Y., Habu, M., Iwanaga, K., Khanal, A. & Nishikawa, T., Apr 1 2009, In : International Journal of Oral and Maxillofacial Surgery. 38, 4, p. 377-381 5 p.

Research output: Contribution to journalArticle

Bone and Bones
Equipment and Supplies
Sagittal Split Ramus Osteotomy
Light
Mandible
17 Citations (Scopus)

Anti-inflammatory activity of a globular adiponectin function on RAW 264 cells stimulated by lipopolysaccharide from Aggregatibacter actinomycetemcomitans

Kamio, N., Akifusa, S., Yamaguchi, N., Nonaka, K. & Yamashita, Y., Aug 1 2009, In : FEMS Immunology and Medical Microbiology. 56, 3, p. 241-247 7 p.

Research output: Contribution to journalArticle

Aggregatibacter actinomycetemcomitans
Adiponectin
Lipopolysaccharides
Anti-Inflammatory Agents
Interleukin-10

Evaluating occlusal caries using a non-destructive Micro-CT examination

Kawato, T., Furuta, M., Ogiso, B., Yamashita, Y., Kitami, S., Iida, T., Kuwabara, A. & Maeno, M., Oct 20 2009, In : Journal of Hard Tissue Biology. 18, 1, p. 35-39 5 p.

Research output: Contribution to journalArticle

Tomography
Tooth
Sensitivity and Specificity
Canes
Three-Dimensional Imaging
26 Citations (Scopus)

Globular adiponectin-induced RAW 264 apoptosis is regulated by a reactive oxygen species-dependent pathway involving Bcl-2

Akifusa, S., Kamio, N., Shimazaki, Y., Yamaguchi, N., Nishihara, T. & Yamashita, Y., May 1 2009, In : Free Radical Biology and Medicine. 46, 9, p. 1308-1316 9 p.

Research output: Contribution to journalArticle

Adiponectin
Reactive Oxygen Species
Apoptosis
DNA Damage
DNA
3 Citations (Scopus)

Influence of oral health on febrile status in long-term hospitalized elderly patients

Shimazaki, Y., Tomioka, M., Saito, T., Nabeshima, F., Ikematsu, H., Koyano, K. & Yamashita, Y., May 1 2009, In : Archives of Gerontology and Geriatrics. 48, 3, p. 411-414 4 p.

Research output: Contribution to journalArticle

Oral Health
Fever
confidence
health
Tongue
3 Citations (Scopus)

Involvement of Ca2+ in globular adiponectin-induced reactive oxygen species

Akifusa, S., Kamio, N., Shimazaki, Y., Yamaguchi, N. & Yamashita, Y., Apr 17 2009, In : Biochemical and Biophysical Research Communications. 381, 4, p. 649-653 5 p.

Research output: Contribution to journalArticle

Adiponectin
Reactive Oxygen Species
Nitric Oxide
calmidazolium
Macrophages
14 Citations (Scopus)

Kinase activity of the dgk gene product is involved in the virulence of Streptococcus mutans

Shibata, Y., van der Ploeg, J. R., Kozuki, T., Shirai, Y., Saito, N., Kawada-Matsuo, M., Takeshita, T. & Yamashita, Y., Apr 27 2009, In : Microbiology. 155, 2, p. 557-565 9 p.

Research output: Contribution to journalArticle

Diacylglycerol Kinase
Streptococcus mutans
Virulence
Phosphotransferases
Genes